>SEQF1516_EDU83242.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNNKRVICELNELTQSAISYNNAVSEIINVWFESLTNCERDESTTRLTFAISELLNISTSKIESISEKINGLSGHAIGE
>SEQF1516_EDU83243.1 hypothetical protein ECH7EC4501_4071 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAETVQAAISTVINKSAKAGLSGVIIHTVTCIQDEE
>SEQF1516_EDU83244.1 ribosomal protein L14 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFD
GNACVLLNNNSEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
>SEQF1516_EDU83245.1 ribosomal protein S17 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKLHVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVE
KAVL
>SEQF1516_EDU83246.1 hypothetical protein ECH7EC4501_0001, partial [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
EDVYGGFIALASVNAMAADCAKGKIEFSKYNEDDTFTVKVDGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTCESGSGFA
EVQFNND
>SEQF1516_EDU83247.1 3-oxoacyl-[acyl-carrier-protein] reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDPASIESVLEKIRAEFGEV
DILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIG
FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILVQVPAGRLGGAQEIANAVAFLASDEAAYITGETLHVNGG
MYMV
>SEQF1516_EDU83248.1 sulfur relay protein TusC/DsrF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRIAFVFSTVPHGTAAGREGLDALLATSALTDELAVFFIADGVFQLLPGQKPDAVLARDYIATFKLLDLYDIEQCWVCA
ASLRERGLDPQTPFVVEATPLEADALRRELANYDVILRF
>SEQF1516_EDU83249.1 sulfurtransferase TusD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFAIVVTGPAYGTQQASSAFQFAQALIAEGHKLSSVFFYREGVYNANHLTSPASDEFDLVRGWQQLNAQHGVALNICVA
AALRRGVVDEMEAGRLGLASSNLQQGFTLSGLGALAEASLTCDRVVQF
>SEQF1516_EDU83250.1 shiga toxin 2 B subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKMFMAVLFALASVNAMAADCAKGKIEFSKYNEDDTFTVKVDGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTCESGSG
FAEVQFNND
>SEQF1516_EDU83251.1 major tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSALYERSQLTQVMISSAPATAETMEKAEYLRLDCTIKEVQFTAGQKQDIDVTTLCSTEQENINGLGASSEISMSGNFYL
NQAQNALRDAYDNDALYAFKVLFPSGKGFKFLAEVRQHTWSSGTNGVVAATFSLRLKGKPVSFVVPLAFVKNPDKTLTVN
TGALLTMSVSVNGGTPPYKHAWKKDGQPVEGQTTDTFSKANTQSGDKGAYTCEVTDSAEQPQSITSDACTVTVNGAGG
>SEQF1516_EDU83252.1 hydrolase, TatD family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTLPGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDL
RRLAAEEGVVALGETGLDYYYTPETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTED
RETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKENQPAMVRDVAEYMAVLKGVAVE
ELAQVTTDNFARLFHIDASRLQSIR
>SEQF1516_EDU83253.1 ribosomal protein S10 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPTRKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPT
EKTVDALMRLDLAAGVDVQISLG
>SEQF1516_EDU83254.1 hypothetical protein ECH7EC4501_2280 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKSTVLCANAAKRVKKQQTEKKIKKVLVQKIGIPIMRLR
>SEQF1516_EDU83255.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLTCAISGDSLAYRFTGDTPEQWLASFRQHRWDLEEEAENLIQEQSEDDQGWVWLP
>SEQF1516_EDU83256.1 ribosomal RNA large subunit methyltransferase J [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQSDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRII
ACDLLPMDPIVGVDFLQGDFRDELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGS
FVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP
>SEQF1516_EDU83257.1 putative RNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLSTKQKQHLKGLAHPLKPVVLLGSNGLTEGVLAEIEQALEHHELIKVKIATEDRETKTLIVEAIVRETGACNVQVIGK
TLVLYRPTKERKISLPR
>SEQF1516_EDU83258.1 twin arginine-targeting protein translocase, TatA/E family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMNDDDAAAKKGADVDLQAEKLSHKE
>SEQF1516_EDU83259.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDDVTVNQTDNVTGREFTSATLSSTNWQYACSCSAGKAVKLVYMVSPVLTTTGHQTGYYKLNDSLDIKTMNRPGNPGD
>SEQF1516_EDU83260.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU83261.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKITTGVSYTTSAVGTGYWLLQLLDKVSPSQWVAIGVLGSLLFGLLTYLTNLYFKIKEDRRKAARGE
>SEQF1516_EDU83262.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGIPPPDTTFEGNPGTATDTTLFPPQDIYPPGVQSFDSAR
>SEQF1516_EDU83263.1 putative terminase subunit encoded by cryptic prophage CP-933P [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTTQKRKFALALMSGKNKTASALAAGYSAKTARVKGSQLAKDPEVLAFIARKQCETVEVDEVPVYRQKKSEPEDKPRRR
EAAAIPQPDETNPEMPPPVVISPGIEYMEDGLPDPVKAMGRLLVENINTDPRLALDAAYKLAQFTHHKKGDAGKKSAKGD
AAKKAANRFAVPPPPRLVVNNDNEGNG
>SEQF1516_EDU83264.1 pemK protein 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKS
IAWRARGATKKGTVAPEELQLIKAKINVLIG
>SEQF1516_EDU83265.1 pemI protein 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLIIEPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKE
VW
>SEQF1516_EDU83266.1 fatty acid metabolism transcriptional regulator FadR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVTRTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGL
NILETLARLDHESVPQLIDNLLSVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPI
YGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHESGEIWHRMQKNLPGDLAIQGR
>SEQF1516_EDU83267.1 HNH endonuclease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDLCDSELDHRIALQFGGGNEETNLWTLCTECHRQKSASEAASGMPDPTLPELPDGTLRADGITGL
>SEQF1516_EDU83268.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISDKLITLVKSLCVLVGISFLVMLVAIFFSTAWRVLTLSGLVG
>SEQF1516_EDU83269.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRVLCVVIIVLAVGCGALWLATNHYRDNALTYKAQRDKKARELEQANATITDMQVRQRDVAALDAKYSRELADARAENE
TLRADVAAGRKRLRINATCSGTVREATGTSGVDNATGPRLADTAERDYFILRERLMTMQKQLEGAQDYIRTQCLN
>SEQF1516_EDU83270.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGIPPPDTTFEGNPGTATDTTLFPPQDIYPPGVQSFDSAR
>SEQF1516_EDU83271.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSKNRPRRTTTRNIRFPNQMIEQINIALDQKGSENFSAWVIESCRRELAADIKYARQLTIKKNDTQYALRWLFI
>SEQF1516_EDU83272.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEHLMSDVPFWQSKTLDEMSDAEWESLCDGCGQCCLHKLMDEDTDEIYFTNVACRQLNIKTCQCRNYERRFEFEPDCIK
LTRENLPTFEWLPMTCAYRLLAEGKDLPAWHPLLTGSKAAMHGERISVRHIAVKESEVIDWQDHILNKPDWAQ
>SEQF1516_EDU83273.1 hypothetical protein ECH7EC4501_4375 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRHYVKTHLITSLAQRCKFCRRFQAAKSITKRELSKNAHRK
>SEQF1516_EDU83274.1 fumarylacetoacetate hydrolase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSAVPEEPVLFIKPETALCDLRQPLAIPSDFGSVHHEVELAVLIGAT
LRQATEEHVRKAIAGYGVALDLTLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPAAEFTGDPQNTTLGLSVNGEQRQQG
TTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGVGPLQSGDELTVTFDGHSLTTRVL
>SEQF1516_EDU83275.1 protein UmuC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFALCDVNAFYASCETVFRPELWGKPVVVLSNNDGCVIARNAEAKALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADM
SNRVMSTLEELSPRVEIYSIDEAFCDLTGVRNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
GGVVDLSNLERQRKLMSALPVDDVWGIGRRISKKLDAMGIKTVLDLADTDIRFIRKHFNVVLERTVRELRGEPCLQLEEF
APTKQEIICSRSFGERITDYTSMRQAICSYAARAAEKLRSEHQYCRFISTFIKTSPFALNEPYYGNSASVKLLTPTQDSR
DIINAATRSLDAIWQAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMAVMDTLNAKEGRGTLYFAGQGIQQQW
QMKRAMLSPRYTTRSSDLLRVK
>SEQF1516_EDU83276.1 cyd operon protein YbgT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI
>SEQF1516_EDU83277.1 tol-pal system-associated acyl-CoA thioesterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTTLFRWPVRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHHFSQQALMAERVAFVVRKMTVEYYAPARLDDMLEIQT
EITSMRGTSLVFTQRIVNAENTLLNEAEVLVVCVDPLKMKPRALPKSIVAEFKQ
>SEQF1516_EDU83278.1 cyd operon protein YbgE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFWDPSRFAAKTSELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGIFCPLLADIVLIVGLIFFFF
>SEQF1516_EDU83279.1 protein TolQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNAAAREAEAFEDKFWSGIELSRLYQESQGKRDNLTGSE
QIFYSGFKEFVRLHRANSHAPEAVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILHRQAFTVSESNKG
>SEQF1516_EDU83280.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRVLCVVIIVLAVGYGALWLATNHYRDNALTYKAQRDKKARELEQANATITDMQVRQRDVAALDAKYSRELADARAENE
TLRADVAAGRKRLRINATCSGTVREATGTSGVDNATRPRLADTAERDYFILRERLMTMQKQLEGAQEYIRTQCLN
>SEQF1516_EDU83281.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISDKLITLVKSLCVLVGISFLVMLVAIFFSTAWRVLTLSGLVG
>SEQF1516_EDU83282.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPPGDVNQLTINAGYRESPHNTVFGFNCSACAQPHSPHHKIHFKKGGRAVTE
>SEQF1516_EDU83283.1 division inhibition protein DicB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METLLPNVNTSEGCFEIGVTISNPVFTEDAINKRKHERELLNKICILSMLARLRPIQKGCWQ
>SEQF1516_EDU83284.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTAFALVLTVFLVSGEPVDIAVSVHRTMQECVTAATEQKIPGNCYPVDKVIHQDNNEIPAGL
>SEQF1516_EDU83285.1 hypothetical protein ECH7EC4501_2313 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCSRDKGCAKSRGERQALHDTSGKNGIHGLNYDIRDGIKKSALL
>SEQF1516_EDU83286.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPYYSKCTTGRHLTFRVTLLTSFTEIDTSDACFTLLRGGNK
>SEQF1516_EDU83287.1 rare lipoprotein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEISGADPRFEPLNATANQDYQRDGKSYKIVQDPSRFIQA
GLAAIYDAEPGSNLTASGEAFDPTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSN
NTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGTSSVSGPQGDILPVSNSTLKSEDPTGAPVTSSGFL
GAPTTLAPGVLEGSEPTPAPQPVVTAPSTTPATSPAMVTPQAASQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGR
VTQNGAVWRIQLGPFANKAEASTLQQRLQTEAQLQSFITTAQ
>SEQF1516_EDU83288.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDTRFVQAHKEARWALGLTLLYLAVWLVAAYLPGVAPGFTGFPRWFEMACILTPLLFIGLCWAMVKFIYRDIPLEDDDAA
>SEQF1516_EDU83289.1 putative tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNDFKAFATDRNANVMSQEEWEALPALISGFTAGKASSAQVNKVIRQASFIAAALAQFVSDKTQRDVLDNGDLPGFVE
LLGSGFAVEYLSRKNPFGDIKSDGTVKTALQNLGLGEGAPAIGVPFFWPSAAMPNTVIDSWSCMVFLKFNGAKFSATDYP
VLAKVFPSLVLPEARGDFIRIWDDGRGADGGRELLSWQAATNFSQFAGNIGEGAGHAINFHDGIAGNQPGFSRFNFTSNS
VGDGVNFVAVRPRNIAFNFLVRAK
>SEQF1516_EDU83290.1 tail fiber assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDEYVYSARHNAFFPVDMIDKYKSEGWDLSDAKEVNQNIISEFMAEPPQGKIRIAGDDGLPAWADIPPPTHEELIEITES
ERQLLINQANEYMNSKQWPGKAAIGRLKGDELTQYNLWLDYLDALELVDTSGAPDIEWPTPPAVQAR
>SEQF1516_EDU83291.1 replication protein P for prophage CP-933H [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIAAQMVNFDREQMRRIANIDNQDMTISVWVFPDTDISDVSRELIAAIKQGYLTVKAAGVWAGGIETPSVETPSEGSK
FFGFDMDNEFISGFDVGAWGVLL
>SEQF1516_EDU83292.1 caudovirales tail fibre assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPVFDENGLATVPGDMRCFYYDAETSEYTGWSDEYINTGVSMPACSTGIDPGENIPGRVAVFTGKGWSHEEDHRNETVY
SIENGAAVTVDYIGAIKDGYVTISPLTPYDKWDGEKWVTDTEAQHSAAVDAAEAQRQSLIDAAMASISLIQLKLQAGRKL
TQAETTRLNAVLDYIDAVTATDTSTAPDVIWPELPEA
>SEQF1516_EDU83293.1 trigger factor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGFRKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAII
KEKINPAGAPTYVPGEYKLGEDFTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFPEEYHAENLKGKAAKFAINLKKV
EERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMERELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQ
RFGGNEKQALELPRELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNKELMDNMRN
VALEEQAVEAVLAKAKVTEKETTFNELMNQQA
>SEQF1516_EDU83294.1 hypothetical protein ECH7EC4501_4380 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLSALFQYVAKDFMKNGLRAVLFCLDFALFAQHSDENCPGIVKKYATARNNRSRLIKVMPL
>SEQF1516_EDU83295.1 drug resistance transporter, Bcr/CflA subfamily [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVSASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTI
FALGSLGMLWVENAAMLLVLRFVQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQ
AIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSEMGYSPAVI
GLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLVLFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQ
ALRPFPHATGRAAALQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNHGNAEVAHS
ESH
>SEQF1516_EDU83296.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSIFLTENELQTLTGCKYASHQRNWLIKNGLPFYTNRSGKPIVSRELFTCIKTLPPREAEPDFGAI
>SEQF1516_EDU83297.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAERFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELG
LEWLDGFHEVLIYPAPFVVDDEWEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGD
RASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSEYFFSAPELFAPRFPSLWQRFCQ
FYQQDPLQRLHHANDTDSFSATNVH
>SEQF1516_EDU83298.1 site-specific recombinase, phage integrase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGRRRKNPEHEKLPPKVYPNKYSVWKPTSRESVTLTAIEDGLAALWKKYEETVNHRDRAMTFGRLWEKFLASAYYSELSP
RTQKDYLQHQKKLLAVFGKVLADSVKPEHIRRYMDKRGEQSKTQANHEKSSMSRVYSWGYERGYVKANPCAGVSKFKAKN
RERYVTDKEYQAVLSVAPLPVFIAMEIAYLCAARVSDVLSLKWEQIGNDGIFIQQGKTGKKQIKAWSPRLQAAIEKAKQL
PTSAYVISNQYGNRYMYKGFNEMWVEARNHAGKISGILTDFTFHDLKAKGISDYEGSSRDKQLFSGHKTEGQVLIYDRKV
KVSPTLDVPLPENIPRKYSK
>SEQF1516_EDU83299.1 sugar fermentation stimulation protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESNFIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALSRPWPKGEMIIAKALGTDPWVIWPSRYHDPQTHEFIDR
TQLMRSYTKPKK
>SEQF1516_EDU83300.1 ribosomal protein L27 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTKFHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFI
SIEAE
>SEQF1516_EDU83301.1 octaprenyl-diphosphate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGGKRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTAT
LLHDDVVDESDMRRGKATANAAFGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITE
ENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNADGEQLGKNVGDDLNEGKPTLPL
LHAMHHGTPEQAQMIRTAIEQGNGRHLLKPVLEAMNACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQ
RDR
>SEQF1516_EDU83302.1 ribosomal protein L21 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANGEEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRR
KHYRKQQGHRQWFTDVKITGISA
>SEQF1516_EDU83303.1 nucleoid-associated protein NdpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELHRVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAF
SRAATGRLRDELAKYPFADGGFVLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETN
PESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAERQNVRQQVYSYCNEQLQAGEEI
ELESLSKELAGVSEVSFTEFAAEKGYELEESFPADRSTLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTP
PNLRDQLQRRTSGGN
>SEQF1516_EDU83304.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPQISRYSDEQVEQLLAELLNVLEKHKAPTDLSLMVLGNMVTNLINTSIAPAQRQAIANSFARALQSSINEDKAH
>SEQF1516_EDU83305.1 ribosomal L25p family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDHDKVMNIQAKAEFYSEVLTIVVDGKEIKVKAQDVQRH
PYKPKLQHIDFVRA
>SEQF1516_EDU83306.1 hypothetical protein ECH7EC4501_4603 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKGQHITVATVFFLLFYALNHSRYAAFCKMTAIFYCVA
>SEQF1516_EDU83307.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGMLISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIF
TLGNVLSAIAPDYMTLMLSRILTSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
SFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMFTLYTYISPVLQSITHATPVFVT
AMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLLMVIMLAIPFLARNKFGAAISMAVWGAATFAVVPPLQMRVMRVAS
EAPGLSSSVNIGAFNLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS
>SEQF1516_EDU83308.1 hypothetical protein ECH7EC4501_2263 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCGNKKGENLMSTDLKFSLVTTIIVLGLIVAVGLTAALH
>SEQF1516_EDU83309.1 transcriptional repressor PurR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELHYSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEA
VEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVID
NAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQGDFEPESGYRAMQQILSQPHRP
TAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIE
VHPRLIERRSVADGPFRDYRR
>SEQF1516_EDU83310.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLILIAMMASGLVACAQSTAPQEDSRLKEAYSACINTAQGSPEKIEACQSVLNVLKKEKQHQQFADQESVRVLDYQQC
LRATQTGNDQAVKADCDKVWQEIRSNNK
>SEQF1516_EDU83311.1 ferric uptake regulation protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVF
ELTQQHHHDHLICLDCGKVIEFSDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK
>SEQF1516_EDU83312.1 hypothetical protein ECH7EC4501_5856, partial [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVMQQAYAAPMMQQPAQSNAAA
>SEQF1516_EDU83313.1 quinone oxidoreductase, YhdH family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHAG
QEVLLTGWGVGENHWGGLAEQARVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVG
STAVALLHKLGYQVVAVSGRESTHEYLKSLGASRILPRDEFAESRPLEKQVWAGAIDTVGDKVLAKVLAQMNYGGCVAAC
GLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPERRAQAWQRLVADLPESFYTQAAKEISLSEAPNFAEAIINNQIQGRTL
VKVN
>SEQF1516_EDU83314.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSLFNRLTGKAVSRTAFVEHLGHEVVQHHPNWKVMISTDHKLMRIDTPLNSYY
>SEQF1516_EDU83315.1 ATP-dependent Clp protease ATP-binding subunit ClpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQP
TLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVM
ADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIG
STTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAID
VIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAG
LGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAV
LLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEF
RNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANEL
LFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
>SEQF1516_EDU83316.1 hypothetical protein ECH7EC4501_6017 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSVISKEVTDFLFMGWNGENPIFGGEGNLLIISAAGKGKDKKG
>SEQF1516_EDU83317.1 translation initiation factor IF-1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>SEQF1516_EDU83318.1 hypothetical protein ECH7EC4501_2677 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEEIKQSATVMIDHEILNELKKLQFDVIRRMNEAGIYGRAATPTIGHLARVLLRERLGIATGEA
>SEQF1516_EDU83319.1 putative transcription antitermination protein NusG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAITEREASIIKAIGEETRDTIAPLMEKIAELETRINKLSNEVEGLISLLGEQ
>SEQF1516_EDU83320.1 gp80 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEYITDPIDVLTEIMNDKQQSTEIRLQAAAVLMPYFHETLNPCFQEDEEDDL
>SEQF1516_EDU83321.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHTSGKLNNQKKPHNRAIDLTEHWLRVAIKIIDRHTREGYAKENPELISAFMTTAAANFATLTEREIAEAEQVTTINVKS
AGE
>SEQF1516_EDU83322.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALTTKKKRFADALSRGANPTEAAIHAGYSEKTARVKGWQLSNDPEVKKYLKAVTSDVTFQVTKPKKVTKKVTEKVTPER
ASINTIEMMDNGLPDPIKAMGRILIDNMDTDPKLALDAAFKLAQFTHRKIGSIGKKEVKKLNAASVYSNRFPIPKPPTDL
KH
>SEQF1516_EDU83323.1 ribonuclease T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITLKMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGI
DPNDPDRGAVSEYEALHEIFKVVRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALG
QTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLPAAEEV
>SEQF1516_EDU83324.1 N-ethylmaleimide reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSEKLYSPLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAEYYRQRASAGLIISEATQISAQAKGYAGAPGIHSPEQ
IAAWKKITAGVHAENGHMAVQLWHTGRISHASLQPGGQAPVAPSALSAGTRTSLRDENGQAIRVETSMPRALELEEIPSI
VNDFRQAIANAREAGFDLVELHSAHGYLLHQFLSPSSNHRTDQYGGSVENRARLVLEVVDAGIEEWGADRIGIRVSPIGT
FQNTDNGPNEEADALYLIEQLGKRGIAYLHMSEPDWAGGEPYTDAFREKVRARFHGPIIGAGAYTVEKAETLIGKGLIDA
VAFGRDWIANPDLVARLQRKAELNPQRAESFYGGGAEGYTDYPTL
>SEQF1516_EDU83325.1 lactoylglutathione lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFVGYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVD
NAAEACEKIRQNGGNVTREAGPVKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN
>SEQF1516_EDU83326.1 putative monothiol glutaredoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTTIEKIQRQIAENPILLYMKGSPKLPSCGFSAQAVQALAACGERFAYVDILQNPDIRAELPKYANWPTFPQLWVDGEL
VGGCDIVIEMYQRGELQQLIKETAAKYKSEEPDAE
>SEQF1516_EDU83327.1 RIP metalloprotease RseP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGFGKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPV
VPELRHHAFNNKSVGQRAAIIAAGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPRGPQIEPVLENVQPNSAASKAGL
QAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEIERQGSPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQ
YGPFNAIVEATDKTWQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGIINLFPLPV
LDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
>SEQF1516_EDU83328.1 phosphatidate cytidylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWGQLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNI
HQPLVEISLWASLGWWIVALLLVLFYPGSAAIWRNSKTLRLIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLDVAPVTLLICSIVAALASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLLLLVFRTL
>SEQF1516_EDU83329.1 di-trans,poly-cis-decaprenylcistransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPWFYTAFFCIGFSIPEYRKPCQGIKKRVMLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKAGAKSVRR
AVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRHNVRLRIIGDTSRFNSRLQERIRKSEALTA
GNTGLTLNIAANYGGRWDIVQGVRQLAEKVQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYA
ELYFTDVLWPDFDEQDFEGALNAFANRERRFGGTEPGDETA
>SEQF1516_EDU83330.1 nagD protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIKNVICDIDGVLMHDNVAVPGAAEFLHGIMDKGLPLVLLTNYPSQTGQDLANRFATAGVDVPDSVFYTSAMATADFLR
RQEGKKAYVVGEGALIHELYKAGFTITDVNPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDTHGRGFYPACGALC
AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETILVLSGVSSLDDIDSMPFRPSWI
YPSVAEIDVI
>SEQF1516_EDU83331.1 asparagine synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCSIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDKAILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYN
HQALRAEYGDRYQFQTGSDCEVILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVAS
EMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDFDAVKDNVTDKNELRQALEDSVKSHLMSDVPYGVLLSGGLDS
SIISAITKKYAARRVEDQERSEAWWPQLHSFAVGLPGSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYD
VTTIRASTPMYLMSRKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKAMSAWGVEA
RVPFLDKKFLDVAMRINPQDKMCGNGKMEKHILRECFESYLPASVAWRQKEQFSDGVGYSWIDTLKEVAAQQVSDQQLET
ARFRFPYNTPTSKEAYLYREIFEELFPLPSAAECVPGGPSVACSSAKAIEWDEAFKKMDDPSGRAVGVHQSAYK
>SEQF1516_EDU83332.1 N-acetylglucosamine repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPGGQAQIGNVDLVKQLNSAAVYRLIDQYGPISRIQIAEQSQLAPASVTKITRQLIERGLIKEVDQQASTGGRRAISIV
TETRNFHAIGVRLGRHDATITLFDLSSKVLAEEHYPLPERTQQTLEHALLNAIAQFIDSYQRKLRELIAISVILPGLVDP
DSGKIHYMPHIQVENWGLVEALEERFKVTCFVGHDIRSLALAEHYFGASQDCEDSILVRVHRGTGAGIISNGRIFIGRNG
NVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQRVLNLLKQGYQSRVPLDDCTIKTICKAANKGDSLASEVIEYVGR
HLGKTIAIAINLFNPQKIVIAGEITEADKVLLPAIESCINTQALKAFRTNLPVVRSELDHRSAIGAFALVKRAMLNGILL
QHLLEN
>SEQF1516_EDU83333.1 hypothetical protein ECH7EC4501_2351 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISNTPKIEHITFSVNLVFVACCVCLFKKMPQSSTVRKRFGGEKIKNVMVIADL
>SEQF1516_EDU83334.1 ribokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIPNMQNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKGANQAVAAGRSGANIAFIACTGDDSIGESVRQ
QLATDNIDITPVSVIKGESTGVALIFVNGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAAKI
AHQNKTIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIRTVLITLGSRGVWASVNG
EGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKPLPEAIRFAHAAAAIAVTRKGAQPSVPWREEIDAFLDRQR
>SEQF1516_EDU83335.1 ribose operon repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELNYAPSALARSLKLNQTHTIGMLITASTNPFYSELVRG
VERSCFERGYSLVLCNTEGDEQRMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTGDFEFNGGFDAMRQLLSHPLRPQ
AVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDIELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQL
TPILMERGSA
>SEQF1516_EDU83336.1 ribose ABC transporter, periplasmic ribose-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSLKDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTV
RGTKILLINPTDSDAVGNAVKMANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGT
SAARERGEGFQQAVAAHKFNVLASQPADFDRTKGLNVMQNLLTAHPDVQAVFAQNDEMALGALRALQTAGKSDVMVVGFD
GTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKVLKGEKVQAKYPVDLKLVVKQ
>SEQF1516_EDU83337.1 drug resistance MFS transporter, drug:H+ antiporter-1 (DHA2) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDKKKRSMAGLPWIAAMAFFMQALDATILNTALPAIAHSLNRSPLAMQSAIISYTLTVAMLIPVSGWLADRFGTRRIFT
LAVSLFTLGSLACALSNSLPQLVVFRVIQGIGGAMMMPVARLALLRAYPRNELLPVLNFVAMPGLVGPILGPILGGVLVT
WATWHWIFLINIPIGIAGLLYARKHMPNFTTARRRFDITGFLLFGLSLVLFSSGIELFGEKIVASWIALTVIVTSIGLLL
LYILHARRTPNPLISLDLFKTRTFSIGIVGNIATRLGTGCVPFLMPLMLQVGFGYQAFIAGCMMAPTALGSIIAKSMVTQ
VLRRLGYRHTLVGITVIIGLMIAQFSLQSPAMAIWMLILPLFILGMAMSTQFTAMNTITLADLTDDNASSGNSVLAVTQQ
LSISLGVAVSAAVLRVYEGMEGTTTVEQFHYTFITMGIITVASAAMFMLLKTTDGNNLIKRQRKSKPNHVPSESE
>SEQF1516_EDU83338.1 exopolysaccharide synthesis regulator RcsF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSRSPVEPVQSTAPQPKAEPAKPKAPRATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINAS
KMKANAVLLHSCEVTSGTPGCYRQALCIGSALNITAK
>SEQF1516_EDU83339.1 D-methionine ABC transporter, periplasmic D-methionine-binding lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQVAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGD
IDANAFQHKPYLDQQLKDRGYKLVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKNGIFVEDKDSPYVNLIVTREDNKDA
ENVKKFVQAYQSDEVYEAANKVFNGGAVKGW
>SEQF1516_EDU83340.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRL
GGNARMGVFATRSTFRPNPIGMSLVELKEVVCHKDCVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
MAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNVRWRVTDAGFEVFALEPR
>SEQF1516_EDU83341.1 prolyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLPTGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLW
QESGRWEQYGPELLRFVDRGERPFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGEDDVVFSDTSDYAANIELAEAIA
PKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIKKTVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLT
FATEEEIRAVVKAGPGSLGPVNMPIPVVIDRTVAAMSDFTAGANIDGKHYFGINWDRDVATPEVADIRNVVAGDPSPDGQ
GTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTRVVAAAIEQNYDERGIVWPDAIAPFQVAILP
MNMHKSFRVQELAEKLYSELRAQGIEVLLDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTG
DIVEYLVKQIKG
>SEQF1516_EDU83342.1 repressor protein CI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMKKKPLTPEQLEDAKRLKSIFNAKKKELGLSQESLAYELGVTQSAVNQLMAGINAINASHAAQLAKILNVKVGDFSPS
LAKSIAEMALAIEEPLTRVPAYEYPLLSCVQAGAFSMDDISYTAKDAIKWISTTTKASDRSFWLEVKGHSMTAPQGGKPS
FPEGMLILVDPEREIEDGDFCVARMNGDEFTFKRFIRESGKAYLEPLNPRFDMIECNENCQFVGKVIKSQWNDETFD
>SEQF1516_EDU83343.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLRELARRGTEGFVLLRMPKKLTSYSDAGIDIIPANGKGASC
>SEQF1516_EDU83344.1 helicase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKITPNFAQERGLNQLRHQWKQHRTYLMYAPTGSGKTGLAAFVTAGMVERGMRVMFVCPYTILLNQTAERFTEYGLPWE
EISFVWRDHPNYDPSRLIQIASADTLIRREFPDNIDLLIIDEAHMKRRALLEVIRDRDIRVLGLSGTPFAAWMGKYYECL
IKPTTIRELIQRGDLSDYEFFAPSMPDLAGVKTSNTVFGRDYNEEQLASIMGSSDLVGDIVRNWLENGEDLPTICFCVNV
AHANFVTREFLQSGIGAEVMTADTPHDERQDIIRRFEEGATKIIVNVGVLVAGFDSDVRCLIYARPTKSEIRWLQCIGRA
LRTASGKKRALIFDHSGTVHRLGFPEDIEYDELPGKNDGMQASAGGSEVKAEKLPRKCPKCHFMKPAGVHMCPKCGFRPL
GGDDVATDRDRKLSRVNKGKREYSREEKQRWWSEIKGYQNYRNATGKPLSDGWCAHTYKEKFGVWPKGFSNAPLQTSVEV
YNFIKSKTIAYAKGRKKAMTGGQHAD
>SEQF1516_EDU83345.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEIEMIKAANGVFELAYERDLPRLAKFKNGEQYTLEAKLTRNPSFHRKMFAFLNFCFQYWCAEHAGYEFSDEATQFDEFR
KNLTILAGFYDVVTTIRGEVRYRAKSLSYANMDQDEFERCYNSMINAALKHVFGRSNSPELNNRLLSFF
>SEQF1516_EDU83346.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMKKETLADYVYRFGQKKAAKDFGVAQSAISKALLVGREIYVKTFDDGRVEAEEVRPFPAFVRGDD
>SEQF1516_EDU83347.1 hypothetical protein ECH7EC4501_1152 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGQGACIVQEGQQGKTERQHPVTGVCPEVRESQPWLDAFASSGTEVSPDTMMAVSCARNNFTCN
>SEQF1516_EDU83348.1 putative phage DNA primase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTKKAAVGHWGRIFEYYGMPPVTGVKHYNGPCPICGARGKFRCDDKDGSGSWICVCGHGDGMELLQLATGKPWVTLCDE
IDRLIGNTWKREKVSQPVTEISRKRKLVMDKFSRLSCLRGTTGEAYLQGRGILQLPTESVRFCDRQIASGREYQAIYAIA
TDDKGSLCYLHRTLLDGDRKANVEAAKKMTALQELPGLQYAKSVAIRLYPVSSTLGIAEGIETALSCRQIFRCNVWSTMN
SGFMEKFIAPPGVNHLIIFADNDEHGAGLAAAFKCGHKNLMSRNDVEKVSIRWPDLPDFNDMLIQGGEAREHVLTRKFKA
EAA
>SEQF1516_EDU83349.1 UDP-N-acetylenolpyruvoylglucosamine reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQHATAEGQPVLILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWY
LHVGAGENWHRLVKYTLQEGMPGLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDCVELATGKQVRLTAKECRFGYRD
SIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFDAVCHMRTTKLPDPKVNGNAGSFFKNPVVSAET
AKALLSQFPTAPNYPQADGSVKLAAGWLIDQCQLKGMQMGGVAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNV
WLEPEVRFIGASGEVSAVETIS
>SEQF1516_EDU83350.1 bifunctional protein BirA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLRDWGVDVFTVPGKGYSLPEPIQLLNAEQILGQLDGGS
VTVLPVIDSTNQYLLDRIGELKSGDACVAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEV
LRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESVVNQGWITLQEAGINLDRNTLAA
MLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPVKLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAE
K
>SEQF1516_EDU83351.1 hypothetical protein ECH7EC4501_6215 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLFYTHKHVSGGHSSIGKAIFAMARHSSVEWVNGQEGNTRWGGIIRKNLSQEAIVEKQCDRYSI
>SEQF1516_EDU83352.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELKSVEDTSWLQLFIKNTALCKHESGRIRCDACPVPEG
>SEQF1516_EDU83353.1 pantothenate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINEDLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFL
GTNGQRIPYIISIAGSVAVGKSTTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFV
SDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVFVSDFVDFSIYVDAPEDLLQTWY
INRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMTLWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK
>SEQF1516_EDU83354.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPDELARLTGYSRQTINKWVRKEGWTTSPKPGVQGGKARLVHVNEQVREYIRNAERPEGQGEAPALSGDAPLEVLLVTL
AKEMTPVDKNSLHPCFCGKGLSDCYNA
>SEQF1516_EDU83355.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRLRNKMTTEELAECLGVAKQTVNRWIREKGWKTEKFPGVKGGRARLILVDTQVCEFIQNTPAFHNTPMLLEAEEPLAE
YAPGIRTPAYRQIISAIDNMTHSEQEKVAQFLSREGIRNFLARLDIDESA
>SEQF1516_EDU83356.1 transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKETDIRRGRHCVFLMHVHLFFVTRYRRQIFDYDATEKLRTYFSNVCADFEAELVEMDGEPDHVHLLTNYPPKLAISSL
VNSLKGVSGRLLRRDRPDIAVRYYYKGVLWSPGYFASSCGGAPISVIRQYIEQQQTPGQVENRALYPRPEGRGFTAHRIN
KKRQGYLSCRLSFMR
>SEQF1516_EDU83357.1 IS605 family transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRLQAFKFQLRPGGQQEREMRRFAGACRFVFNRALALQNENHEAGNKYIPYGKMASWLVEWKNATETQWLKDAPSQPLQ
QSLKELERAYKNFFRKRAAFPRFKKRGQNDAFRYPQGVKLDQENSRIFLPKLGWMRYLNSRQVTGVVKNVTVSQSCGKWY
ISIQTESEVSTPVHPSASMVGLDAGVAKLATLSDGTVFEPVNSFQKNQKKLARLQRQLSRKVKFSNNWQKQKRKIQRLHS
CTANIRRDYLHKVTTTVSKNHAMIVIEDLKVSNMSKSAAGTVSQPGRNVRAKSGLNRSILDQGWYEMRRQLEYKQLWRGG
QVLAVPPAYTSQRCACCGHTAKENRLSQSKFRCQVCGYTANADVNGARNILAAGHAVLACGEMVQSGRSLKQEPTEMIQA
TA
>SEQF1516_EDU83358.1 carboxylate/amino acid/amine transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRFLAAGILLLAFLLLRGHKLPPLRPLLNAALIGLLLLA
VGNGMVTVAEHQNVPSGIAAVVVATVPLFTLCFSRLFGIKTRKLEWVGIAIGLAGIIMLNSGGNLSGNPWGAILILIGSI
SWAFGSVYGSRITLPVGMMAGAIEMLAAGVVLMIASMIAGEKLTALPSLSGFLAVGYLALFGSIIAINAYMYLIRNVSPA
LATSYAYVNPVVAVLLGTGLGGETLSKIEWLALGVIVFAVVLVTLGKYLFPAKPVVAPVIQDASSE
>SEQF1516_EDU83359.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGSSLLTLLDDIATLLDDISVMGKLAAKKTAGVLGDDLSLNAQQVSGVRANRELPVVWGVAKGSLINKVILVPLALIIS
AFIPWAITPLLMIGGAFLCFEGVEKVLHMLEARKHKEDPAQSQQRLEKLAAQDPLKFEKDKIKGAIRTDFILSAEIVAIT
LGIVAEAPLLNQVLVLSGIALVVTVGVYGLVGVIVKIDDLGYWLAEKSSALMQALGKGLLIIAPWLMKALSIVGTLAMFL
VGGGIVVHGIAPLHHAIEHFAGQQSAVVAMILPTVLNLILGFIIGGIVVLGVKAVAKMRGQVH
>SEQF1516_EDU83360.1 diguanylate cyclase (GGDEF) domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENQSWLKKLARRLGPGHIVNLCFIVVLLFSTLLTWREVVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMR
EALVAPLDFTSLRDAVTEFEQHRDEHAWQIELNRRRTLSVNGVSDALVSEGNLLSRENESLDNEITAALEVGYLLRLAHN
SSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRHRAVRWFTSQPEHASNTEPQVTVSVPVDS
NNYWYGVLGMSIPVRTMQQFLRNAIDKNLDGEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDS
RYVSWERLDHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQSSLQWQAWHDTLTRL
YNRGALFEKARPLAKLCQTHQHPFSVIQVDLDHFKAINDRFGHQAGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILP
GASLTEAAEVAERIRLKLNEKEMLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVFASDNA
>SEQF1516_EDU83361.1 very short patch repair protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADVHDKATRSKNMRAIATRDTAIEKRLASLLTGQGLAFRVQDASLPGRPDFVVDEYRCVIFTHGCFWHHHHCYLFKVPA
TRTEFWLEKIGKNVERDRRDISRLQELGWRVLIVWECALRGREKLKDEALTERLEEWICGEGASAQIDTQGIHLLA
>SEQF1516_EDU83362.1 phage tail assembly chaperone [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKDLKTLALARLSGFRHKTVKVPEWGNVSVVLREPSAEAWYLWQEVLNGDGEDDDTLSVVAKTRRNLEADVTLFCDVLC
DTDLQRVFTPDDREQVLAVYGPVHARLLRQALELIADAESARKK
>SEQF1516_EDU83363.1 phage protein, HK97 gp10 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIETLLDFSGLEDISRDLQLLSGAENNRVLREATRAGANVLKEEVVSRAPVRRGKLRRNVVVLSRRSRDGGMESGVHIRG
VNPDTGNSDNTMKADNPRNAFYWRFVEMGTVNMPPHPFVRPAFDVRSEQAAQVAIARMNRAIDEVLRR
>SEQF1516_EDU83364.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTALLTLEEIKAHLRVDHDADDDMLMDKVRQATAVLLAYIQGSRDKVIREDGELIPGEALTRMKGAAMRLTGMLYRNPDL
AEREELIQGELPFSVSVLIYDLRCPTVL
>SEQF1516_EDU83365.1 Gp11 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEADLYPHLAHLAGGQVYPYVVPLLDGRPSVALPWVVFSLISSVSADVMGGQAESSVSVQIDVYAGTVTQARQIRQDAR
EAIMLLAPGSVSEMQDYIPENRCYRATLEFQVTV
>SEQF1516_EDU83366.1 Gp14 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFDRISPLGDERGDIRNAQIVKAVFGAQGMNVALKDAMLCWGEDEDKPEVDPFAALEDALSLAAQS
>SEQF1516_EDU83367.1 putative phage head-tail adaptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAISAGRLTQMISVLNPVLTRNAAGEMTEEWVSCGKIHADIRGRSSRERMQSGAEMAQAEIRIWVRGQSGREITAASRLH
VLSGPWRDRILNVVGLPVPDATGGRLEILCRLGGEK
>SEQF1516_EDU83368.1 helicase IV [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELKATTLGKRLAQHPYDRAVILNAGIKVSGDRHEYLIPFNQLLAIHCKRGLVWGELEFVLPDEKVVRLHGTEWGETQRF
YHHLDAHWRRWSGEMSEIASGVLRQQLDLIATRTGENKWLTREQTSGVQQQIRQALSALPLPVNRLEEFDNCREAWRKCQ
AWLKDIESARLQHNQAYTEAMLTEYADFFRQVESSPLNPAQARAVVNGEHSLLVLAGAGSGKTSVLVARAGWLLARGEAS
PEQILLLAFGRKAAEEMDERIRERLHTEDITARTFHALALHIIQQGSKKVPIVSKLENDTAARHELFIAEWRKQCSEKKA
QAKGWRQWLTEEMQWSVPEGNFWDDEKLQRRLASRLDRWVSLMRMHGGAQAEMIASAPEEIRDLFSKRIKLMAPLLKAWK
GALKAENAVDFSGLIHQAIVILEKGRFISPWKHILVDEFQDISPQRAALLAALRKQNSQTTLFAVGDDWQAIYRFSGAQM
SLTTAFHENFGEGERCDLDTTYRFNSRIGEVANRFIQQNPGQLKKPLNSLTNGDKKAVTLLDESQLDALLDKLSGYAKPE
ERILILARYHHMRPASLEKAATRWPKLQIDFMTIHASKGQQADYVLIVGLQEGSDGFPAAARESIMEEALLPPVEDFPDA
EERRLMYVALTRARHRVWALFNKENPSPFVEILKNLDVPVARKP
>SEQF1516_EDU83369.1 methylglyoxal synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYATGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISE
GKIDVLIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK
>SEQF1516_EDU83370.1 cell division inhibitor SulA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPMMTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQA
SGLPLTKVMQISQLSPCHTVESMVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
LKIHSNLYH
>SEQF1516_EDU83371.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFMLSPLLKRYTWNSAWLYYARIFIALCGTTAFPWWLGDVKLTIPLTLGMVAAALTDLDDRLAGRLRNLIITLFCFFIA
SASVELLFPWPWLFAIGLTLSTSGFILLGGLGQRYATIAFGALLIAIYTMLGTSLYEHWYQQPMYLLAGAVWYNVLTLIG
HLLFPVRPLQDNLARCYEQLARYLELKSRMFDPDIEDESQAPLYDLALANGLLMATLNQTKLSLLTRLRGDRGQRGTRRT
LHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFRFQRLMSMQGQACQQLSRCILLRQPYQHDPHFERAFTHIDAALER
MRDNGAPADLLKTLGFLLNNLRAIDAQLATIESEQAQALPHNNDENELADDSPHGLSDIWLRLSRHFTPESALFRHAVRM
SLVLCFGYAIIQITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLVGIAIGIPVLWFVPSLEGQLVLLVITGVLFF
AFRNVQYAHATMFITLLVLLCFNLLGEGFEVALPRVIDTLIGCAIAWAAVSYIWPDWQFRNLPRMLERATEANCRYLDAI
LEQYHQGRDNRLAYRIARRDAHNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYISALGAHREQLTNPEILA
FLDDAVCYVDDALHHQPADEERVNEALASLKQRMQQLEPRADSKEPLVVQQVGLLIALLPEIGRLQRQITQVPQETPVSA
>SEQF1516_EDU83372.1 TfoX family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVSDGELYLRACEQSAQYCVKYPPVWLTYKKCGRSVTLN
YYRVDESLWRNQLKLVRLSKYSLDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE
>SEQF1516_EDU83373.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTVLNILNFVLGGFATTLGWLLATLVSIALIFTLPLTRSCWEITKLSLVPYGNEAIHVDELNPAGKNVLLNTGGTVLNI
FWLIFFGWWLCLMHIATGIAQCISIIGIPVGIANFKIAAIALWPVGRRVVSVETAQAAREANARRRFE
>SEQF1516_EDU83374.1 sulfate/thiosulfate ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVF
QHYALFRHMTVFDNIAFGLTVLPRRERPNAAAIKAKVTKLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL
DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQADAPDQVWREPATRFVLEFMGEV
NRLQGTIRGGQFHVGAHRWPLGYTPAYQGPVDLFLRPWEVDISRRTSLDSPLPVQVLEASPKGHYTQLVVQPLGWYNEPL
TVVMHGDDAPQRGERLFVGLQHARLYNGDERIEPRDEELALAQSA
>SEQF1516_EDU83375.1 PTS system, glucose-specific IIA component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGLFDKLKSLVSDDKKDTGTIEIIAPLSGEIVNIEDVPDVVFAEKIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSI
ESDSGVELFVHFGIDTVELKGEGFKRIAEEGQRVKVGDTVIEFDLPQLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVG
ETPVIRIKK
>SEQF1516_EDU83376.1 sulfate ABC transporter, permease protein CysW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEVTQLKRYDARPINWGKWFLIGIGMLVSAFILLVPMIYIFVQAFSKGLMPVLQNLADPDMLHAIWLTVMIALIAVPVN
LVFGILLAWLVTRFNFPGRQLLLTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQIMFSWPGMVLVTIFVTCPF
VVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEFGAVSVVSGSIRGETLSLPLQIE
LLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRLENQEKRAQQEENHEH
>SEQF1516_EDU83377.1 phosphoenolpyruvate-protein phosphotransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFLSGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLL
EDEELEQEIIALIKDKHMTADAAAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA
ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYLILDAVNNQVYVNPTNEVIDKMR
AVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAV
AEACGSQAVIVRTMDIGGDKELPYMNFPKEENPFLGWRAIRIAMDRKEILRDQLRAILRASAFGKLRIMFPMIISVEEVR
ALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFSIGTNDLTQYTLAVDRGNDMISHLYQPMSPS
VLNLIKQVIDASHAEGKWTGMCGELAGDERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDE
LMTLVNKFIEEKTIC
>SEQF1516_EDU83378.1 phosphocarrier protein PtsH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASAKSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKL
MAELE
>SEQF1516_EDU83379.1 cysteine synthase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTLEQTIGNTPLVKLQRMGPNNGSEVWLKLEGNNPAGSVKDRAALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIA
ALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQGMEGARDLALEMADRGEGKLLDQFNNPDNPYAHYTTTGPEIWQ
QTGGRITYFVSSMGTTGTITGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPAEYLPGIFNASLVDEVLDIHQRDAENT
MRELAVREGIFCGVSSGGAVAGALRVAKANPGAVVVAIICDRGDRYLSTGVFGEEHFSQGAGI
>SEQF1516_EDU83380.1 pyridoxal kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGLNVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRAL
QERDALRQLRAVTTGYMGTASQIKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNI
FELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMLVVVVTADSVNVISHSRVKTDLKGTGDLFCAQLI
SGLLKGKALNDAVHRAGLRVLEVMRYTQQHESDELILPPLAEA
>SEQF1516_EDU83381.1 transcriptional regulator KdgR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMSKSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELG
ARALQNVDLIRSADIQMREISRLTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEV
KQILEGVEYKRSTERTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFGVVIAGLSISFPTLRFSEERLQE
YVAMLHTAARKISAQMGYHDYPF
>SEQF1516_EDU83382.1 hypothetical protein ECH7EC4501_2300 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHINRYACMNAKTHRGLLFMYACLLGAMMCFMDTPVRTLS
>SEQF1516_EDU83383.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIATDLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGY
RRIYKCGLVVFLLSSLFCALSDSLQILTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIA
AAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLLITALSGFAQGQSLTLIAAELVV
MVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICTSVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVM
APLAGYLIERVHAGLLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRERSGGASGM
LGTARLLGQSSGAALVALMLNQFGDNGTHVSLMAAAILAVIAACISGLRITQPRSRA
>SEQF1516_EDU83384.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEVVNSGVMNIASLVVSVVVLLIGLILWFFINRASSRTNEQIELLEALLDQQKRQNALLRRLCEANEPEKADKKTIESQ
KSVEDEDIIRLVAER
>SEQF1516_EDU83385.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGRIDSVIFVGLIVILIYNNVTNHGALITTWLLSALALM
GFYIFWIRVPKIIFKQKGFFFANVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLERIYKLLVSTQ
>SEQF1516_EDU83386.1 cold shock protein CspC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKIKGQVKWFNESKGFGFITPADGSKDVFVHFSAIQGNGFKTLAEGQNVEFEIQDGQKGPAAVNVTAI
>SEQF1516_EDU83387.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFIIRTVMLIALVWIGLLLSGYGVLIGSKENAAELGLQCTYLTARGTSTVQYLHTKSGFLGITDCPLLRKSNIVVDNG
>SEQF1516_EDU83388.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCGIFSKEVLSKHVDVEYRFSAEPYIGASCSNVSVLSMLCLRAKKTI
>SEQF1516_EDU83389.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW
>SEQF1516_EDU83390.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFGAVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFL
GGRMIIEGFRGADDEDEEPRRRHGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGS
IIGKKAEILGGLVLIGIGVQILWTHFHG
>SEQF1516_EDU83391.1 ribosomal RNA large subunit methyltransferase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFSCPLCHQPLTREKNSYICPQRHQFDMAKEGYVNLLPVQHKRSRDPGDSAEMMQARRAFLDAGHYQPLRDAIVAQLRE
RLNEKATAVLDIGCGEGYYTHAFADALPEITTFGLDVSKVAIKAAAKRYPQVTLCVASSHRLPFSDTSMDAIIRIYAPCK
AEELARVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPHAEQLEGFTLQKSDELCYPMRLRGDEAVALLQMTPFAWRA
KPEVWQILAAKEVFDCQTDFNIHLWQRSY
>SEQF1516_EDU83392.1 hypothetical protein ECH7EC4501_1571 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNTILSKRVIAASILVIMNLFKRLAIDSALKKRKAQILAENDPNNG
>SEQF1516_EDU83393.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRKSATGVIVALAVIWGGGTWYTGTQIQPGVEKFIKDFNDAKKKGEHAYDMTLSYQNFDKGFFNSRFQMQMTFDNGAPD
LNIKPGQKVVFDVDVEHGPLPITMLMHGNVIPALAAAKVNLVNNELTQPLFIAAKNKSPVEATLRFAFGGSFSTTLDVAP
AEYGKFSFGEGQFTFNGDSSSLSNLDIEGKVEDIVLQLSPMNKVTAKSFTIDSLARLEEKKFPVGESESKFNQINIINHG
EDVAQIDAFVAKTRLDRVKDKDYINVNLTYELDKLTKGNQQLGSGEWSLIAESIDPSAVRQFIIQYNIAMQKQLAAHPEL
ANDEVALQEVNAALFKEYLPLLQQSEPTIKQPVRWKNALGELNANLDISIADPAKSSSSTNKDIKSLNFDVKLPLNVVTE
TAKQLNLSEGMDAEKAQKQADKQISGMMTLGQMFQLITIDNNTASLQLRYTPGKVVFNGQEMSEEEFMSRAGRFVH
>SEQF1516_EDU83394.1 acyltransferase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFFSALSMANLLNKFIMTRILAAITLLLSIVLTILVTIFCSVPIIIAGIVKLLLPVPVIWRKVSRFCDFMMYCWCEGLA
VLLHLNPHLQWEVHGLEGLSKKNWYLLICNHRSWADIVVLCVLFRKHIPMNKYFLKQQLAWVPFLGLACWALDMPFMKRY
SRAYLLRHPERRGKDVETTRRSCEKFRLHPTTIVNFVEGSRFTQEKHQQTHSTFQNLLPPKAAGIAMALNVLGKQFDKLL
NVTLCYPDNNRQPFFDMLSGKLTRIVVHVDLQPIADELHGDYINDKSFKRHFQQWLNSLWQEKDRLLTSLMSSQRQDK
>SEQF1516_EDU83395.1 thiol:disulfide interchange protein DsbA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEFFSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHV
NFMGGDLGKDLTQAWAVAMALGVEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKA
AADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK
>SEQF1516_EDU83396.1 protein serine/threonine kinase RdoA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNSAFTFQTLHPDTIMDALFEQGIRVDSGLTPLNSYENRVYQFQDEDRRRFVVKFYRPERWTADQILEEHQFALQLVND
EVPVAAPVAFNGQTLLNHQGFYFAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLF
EDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDLDDARNGPAIQDLWMLLNGDKAE
QRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVYYLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEP
PLQLTPMY
>SEQF1516_EDU83397.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELADLTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTAL
LRARGVIKE
>SEQF1516_EDU83398.1 hypothetical protein ECH7EC4501_1570 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNFVHKLFTSLLIYYHAFYSMMFVFVFHAVKNKSIPNN
>SEQF1516_EDU83399.1 molybdopterin-guanine dinucleotide biosynthesis protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGKTMIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHTHHDMDVDKPGKDSYELRKAGAAQTIVASQQRWALMT
ETPDEEELDLQFLASRMDTSKLDLILVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLDINDVE
GLADFVVEWMQNQDG
>SEQF1516_EDU83400.1 molybdopterin-guanine dinucleotide biosynthesis protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLMTTITGVVLAGGKARRMGGVDKGLLDLNGKPLWQHVADALMTQLSHVVVNANRHQEIYQAGGLKVIEDSLADYPGPL
AGMLSVMQQEAGEWFLFCPCDTPYIPHDLAARLNHQRKDAPVVWVHDGERDHPTIAMVNRAIEPLLLEYLQAGERRVMAF
MRLAGGHAVDFSDHKDAFVNVNTPEELARWQEKR
>SEQF1516_EDU83401.1 hypothetical protein ECH7EC4501_1574 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIHGLFLLFNKYKYILIMHPAAGHYFSISGYSKFCCFIREYLYDT
>SEQF1516_EDU83402.1 phage O protein family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFGGFMSSKLHGLVWEGCAFTGMILSRVAVMARLADYSNDEGVSWPAIETIRRQIGARSESTVKSAIAELAKEGWLTKEE
RKVGGRNVSNIYRLNVEKLEAAAAAARESYKPKRKISPAKNDPLTVDPSNIAPSTVDPSNFDGSTVDNKLPIRGAMIDPD
PSVLKPDPSDKRSSCPDASQPDPQTAEQNFLTRHPDAVVFSAKKRQWGSQEDLVCAQWIWGRIVSLYEQAASDDGEITRP
KEPNWTAWANDVRTMRMLDGRTHRQICEMFGRLQRDSFWVKNIMSPAKLREKWDELVIRLGRSPAQRCVNHISEPDTEIP
PGFRG
>SEQF1516_EDU83403.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTFTKEQLISHVSENVKAMKFAVKQTAFKNSLEAIELDLALALVAQASLEAEPVLYMNRFTGKTFSLEEQPGADKEPEI
YVPLYAAPPDSAAMLQAGNFREKKGSSTNNFREISETSTNYPVTLDDWISCSERMPDDGQHVIILCDGAFVLYAQYRDGE
FFDVVRNGDEFFETQSRNVTDWMPLPEPPQEVRQ
>SEQF1516_EDU83404.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPPRLSYKTGGNMNRALSPMVSEFETIEQENSYNEWLRAKVATSLADPRPAIPHDEVERRMAERFAKMRKERSKQ
>SEQF1516_EDU83405.1 putative repressor protein encoded by cryptic prophage CP-933P [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPEGYLDAEYAEQPGGSPPHAGLTSNQLELLQIFSAFPEDEQRQIISELKQKKESMEDLIARWIAAQKCRRA
>SEQF1516_EDU83406.1 crossover junction endodeoxyribonuclease RusA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIEFVLLYPPTVNTYWRRRGSTYFVSKAGERYRRAVALIVRQQRLKLSLSGRLAIKIIAEPPDKRRRDLDNILKAPLDA
LTHAGLLMDDEQFDEINIVRAQPVSGGRLGVKIYPIMLEGQVKK
>SEQF1516_EDU83407.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGVKTFAGIHTKGGNMSDDISLAMEGALAVIAVVGVYCLVVFLMDRLGN
>SEQF1516_EDU83408.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKHEHIRMAMNVWAHPDGEKVPAAKITKAYFELGMTFPELYDDSHPEALARNTQKIFRWLDKDTPDAVEKMQALLPAI
EKAMPPLLVARMRSHSSEYYREIVERRDRLVKDVDDFVASAVVLYDQMNRGGPAGNAVVMH
>SEQF1516_EDU83409.1 DNA replication protein dnaC homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIAAVGVLERIRRLAPQGAVPPYRTVEEWREWQLAEGRKRSEEINRLNHQVRVEKILNRAGIQPLHRKCSFGNYRVQN
DGQRHALSQAKSIADELMTGCTNFVFSGKPGTGKNHLAAAIGNRLMAKGRSVIIVTVSDVMSVLHDGYDNGQSGEKFLQE
LCGVDLLVLDEIGMQRDTRNEQVTLNQIVDRRTASMRSVGMLTNLNHAAMSTLLGDRVMDRMTMNGGRWVNFNWESWRSN
VGRQGM
>SEQF1516_EDU83410.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVLLRPVLVPELGLVIVKPGRESMSAFHNGRILVEPEPKSMRALPSGVVPAVHQPLAEDKSLLPFFSDERVIRAAGGAG
ALSDWLLRHVKSCQWLHGDYHHSETVIHRYGTGAMVLCWHCDNQLREQTSDSLDQLAQQNLAAWMIDIIRHAMNGAQERE
LSLAELSWWAVRNQVADALPEAVLRRSLGLRAEKIRSVYRESDIIPGEQTATSILKQRTKNIALPPHTHQQQNPPQEKTV
VSIAVDPESPESFMKRPKRRRWVNEKYTRWVKTQPCACCGKPADDPHHLIGHGQGGMGTKSHDIFTLPLCREHHNELHAD
PLAFEEKHGSQVDLIFRFLDHAFATGVLG
>SEQF1516_EDU83411.1 putative exclusion protein ren of cryptic prophage CP-933P [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKPFTHEQREELKARIIGLVRKNERMTISQLERATGAGWHSVRRCLVDVLACGDLYMPGKYGVFTSEQVYRVWRKAAEK
ATDQTLIRKLPDGEIRRYDRQQNIICGECRKSEVMLRVLAFYQGNFQEAVL
>SEQF1516_EDU83412.1 anhydro-N-acetylmuramic acid kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSLKQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVKAL
LKEQNLQARDIVAIGCHGQTVWHEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPT
ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGKVILPLLQNMLSDPYFSQPAPKS
TGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAVTISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTD
AVGISGDDMEALAFAWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANS
>SEQF1516_EDU83413.1 hypothetical protein ECH7EC4501_3903 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYSLVLLILALYSMSLSHLAKSRVPAKVQSLYTWRF
>SEQF1516_EDU83414.1 transcriptional regulator SlyA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQT
CASDRRAKRIKLTEKAEPLISEMEAVINKTRAEILHGISAEELEQLITLIAKLEHNIIELQAKG
>SEQF1516_EDU83415.1 pyridoxamine 5'-phosphate oxidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACEAKLADPTAMVVATVDEHGQPYQRIVLLKHYDEKGMV
FYTNLGSRKAHQIENNPRVSLLFPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGSWVSKQSSRISARGILESKF
LELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
>SEQF1516_EDU83416.1 auxiliary transport protein, membrane fusion protein (MFP) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQVSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPF
QIAELNAQAQLAKAQSDLAKANNEANRRRHLSQNFISAEELDTANLNVKAMQASVDAAQATLKQTQWQLAQTEIRAPVSG
WVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKTLQGHVSSIGRAIYDQSVESDSS
LIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSGTTCSIAVGQ
>SEQF1516_EDU83417.1 superoxide dismutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRFSLAILALVVATGAQAASEKVEMNLVTSQGVGQSIGSVTITETDKGLEFSPDLKALPPGEHGFHIHAKGSCQPATKD
GKASAAESAGGHLDPQNTGKHEGPEGAGHLGDLPALVVNNDGKATDAVIAPRLKSLDEIKDKALMVHVGGDNMSDQPKPL
GGGGERYACGVIK
>SEQF1516_EDU83418.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTMKKLLIIILPVLLSGCSAFNQLVERMQTDTLEYQCDEKPLTVKLNNPRQEVSFVYDNQLLHLKQGLSASGARYSDGIY
VFWSKGEEATVYKRDRIVLNNCQLQNPQR
>SEQF1516_EDU83419.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFMLNATGLPLQDLVFGASVYFPPFFKAFAFGFVIWLVVHRLLRGWIYAGDIWHPLLMDLSLFAICVCLALAILIAW
>SEQF1516_EDU83420.1 fusaric acid resistance domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNASSWSLRNLPWFRATLAQWRYALRNTIAMCLALTVAYYLNLDEPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGAI
AALLLAGHTLNEPWFFLLSMSAWLGFCTWACAHFTNNVAYAFQLAGYTAAIIAFPMVNITEASQLWDIAQARVCEVIVGI
LCGGMMMMILPSSSDATALLTALKNMHARLLEHASLLWQPETTDAIRAAHEGVIGQILTMNLLRIQAFWSHYRFRQQNAR
LNALLHQQLRMTSVISSLRRMLLNWPSPPGATREILEQLLTALASSQTDVYTVARIIAPLRPTNVADYRHVAFWQRLRYF
CRLYLQSSQELHRLQSDVDDHARLPRTSGLARHTDNAEAMWSGLRTFCTLMMIGAWSIASQWDAGANALTLAAISCVLYS
AVAAPFKSLSLLMRTLVLLSLFSFVVKFGLMVQISDLWQFLLFLFPLLATMQLLKLQMPKFAALWGQLIVFMGSFIAVTN
PPVYNFADFLNDNLAKIVGVALAWLAFAILRPGSDARKSRRHIRALRRDFVDQLSRHPTLSESEFESLTYHHVSQLSNSQ
DALARRWLLRWGIVLLNCSHVVWQLRDWESRSDPLSRVRDNCISLLRGVMSERGVQQKSLAATLEELQRICDSLARHHQP
AARELAAIVWRLYCSLSQLEQAPPQGTLAS
>SEQF1516_EDU83421.1 outer membrane lipoprotein SlyB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKRVLVVSMVGLSLVGCVNNDTLSGDVYTASEAKQVQNVSYGTIVNVRPVQIQGGDDSNVIGAIGGAVLGGFLGNTVGG
GTGRSLATAAGAVAGGVAGQGVQSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSPGQRVVLASNGSQVTVSPR
>SEQF1516_EDU83422.1 aldehyde ferredoxin oxidoreductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDEVPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITS
LSTFTKGNLVVDAHMGGFFAAQMKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCV
AAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKRLNDYMMTELIGANNNHVVPSTP
QSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPPGNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNI
PRVKEFGVPSTGGNTCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYSKGVFKRVL
PAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAECWNLGEEYWGYAKNKLWSPFGYPVHHANEASAQ
VGSIVNCMFNRDCMTHTHINFIGSGLPLKLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNW
VWPMTVSPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRNEHDLICSWVFDKDPQI
PVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQRLGLEDIAADLAAHNLLPA
>SEQF1516_EDU83423.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPYSDEENSKMMLANIASIEIPPIYCTYLEWLQKQEASH
LQRYGVKKETLHDRQFLPRILLGEYFRDQFLRLVDQARKQKFAVAVYESCQVTDLQITNAGVMLATNHDLPSETFDLAVI
ATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFIEDDKQHVVFHRDNASEKLNITL
MSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKGEYGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAE
RKQRDQFDWAEKNLQEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPSESIRRLLA
LREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKVKDIPFPGLREQLQKTGDEIPDVGEDYTLQQ
PEDIRGRVAFGALPWLMHDQPFVQGLTACAEIGEAMARAVVKPASRARRRLSFD
>SEQF1516_EDU83424.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNHQDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAEFIRQHSVAGQLVARAVFLSPPYSVAEEELSVLLENI
KQNGDYADIACMTGSQDDYYYSTQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEA
AIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP
>SEQF1516_EDU83425.1 nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVLGLHALLRARGVKKSATDHGERIYLYSKAVRLWHWSN
ALLFVLLLASGLINHFALVGATAVKSLVAVHEVCGFLLLACWLGFVLINGVGGNGHHYRIRRQGWLERAAKQTRFYLFGI
MQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYWLLQAHFALAFISLFFIFGHLYL
CTTGRTPHETFKSMVDGYHRH
>SEQF1516_EDU83426.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYTDWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPG
ERAFCSQFARSDDHARIGCCEDNARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRI
ANTGMRVRVCTLGKRCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTGVVDSIILGPGGSAALAYHDGER
VRFAVAIEGENNIRAGVRYRLNEQHQFVEC
>SEQF1516_EDU83427.1 iron-sulfur cluster-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIHDESRCNGCNICARACRKTNHAPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCIDVCPTGASWRDEQGIVR
VEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLAKGFPPICVSACPEHALIFGREDSPEIQAWLQDNKYYQY
QLPGAGKPHLYRRFGQHLIKKENV
>SEQF1516_EDU83428.1 hypothetical protein ECH7EC4501_4346 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTIQQPDIKHSTNTLLTLSPTPDIFPNPIVYEKIFNADKLILYG
>SEQF1516_EDU83429.1 iron-sulfur cluster-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQEDIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTN
FNDGSVGTFFSRIKIHRNYFFGDNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCS
ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV
>SEQF1516_EDU83430.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCRVVGKVVLEMRDLGQEPKHIVIAGVLRTALANKRIQRSELEKQAMETVINALVK
>SEQF1516_EDU83431.1 putative repressor protein encoded within prophage CP-933O [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHALNLKGKDLVNATGASKGSVSQWMNGGGAPSSRYISSLAKILKVNENWLLNGGELNTGDSLDLSLPPIKTVPLLSLQQ
AASWSDYMKNSSITSCVQLVGEIPANTFAVVLESDSMSTSGGGVSIPNGSTVFVDPDRIVQPGNIVLALPKGTTTPVIRK
LEIEGPDILLVPTNPRYPSIMLDDLSCILGVCFKIQQDI
>SEQF1516_EDU83432.1 IS629 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU83433.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKHEHIRMAMNAWARPDGEKVPAAGITQAYFELGMTFPELYDDSHPEALARNTQKIFRWIEKDTPDAVEKMQALLPAI
EKAMPPLLVARMRSHSSEYYREIVERRDRLVKDVDDFVAAAIAWGTLTNSGGQPGNAVVVH
>SEQF1516_EDU83434.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHYLEKNYPRKSRTTEFLFFILFIVLMIPISPLLLVWIIGRTFEPVIELYTDVTWESFSALHNKINPYKEN
>SEQF1516_EDU83435.1 hypothetical protein ECH7EC4501_2884 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFKDLPPSIQEIAAHTLRHRLNELELESVTKKDTDNMARNVRDAFTGLYFCASINKHDSESVANKIAETTAQNINTKPT
EEEIDQFAHDAGLKNKKEKSPYAGNMFVYDNLIRIRGEIPAEYLARVHQALLKNLETELFDGNTNGFFMVSGLEKDWDAE
KRWNVATWLFSNRAAALEASACICGLFLTDHKYNLDVYSYIYAEHGPLWIDW
>SEQF1516_EDU83436.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEQQIRLVCRQCMDRCRAGETWPPDLAEFVALISESGANPFGLTVDAVMEEYRRWRNESWRYDGSDKYPWPQPVLYHIC
LEMRTRGIERQMTQGELKRLAERQLTKWAKHVGNGMSVPPVRRQLEGAKHPQGPTPIERLKQEYERRKAAGFI
>SEQF1516_EDU83437.1 hypothetical protein ECH7EC4501_2883 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEDKMPNKKRNPLIEKQIECLVNQLRQSGLLKTHSELRLTESAFDDKLNNVLYNGIIDFNRSVGRRGPAGVSL
>SEQF1516_EDU83438.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU83439.1 hypothetical protein ECH7EC4501_2882 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVLTVPRALSRIHRITKFTLKRAAEQPRSKTDTAKRHQKIDNRGRCSGVVT
>SEQF1516_EDU83440.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METVFDALKALKKASSQVVASRLGISREDAVNELWKLKRRGEADNKGSMWWLTQTGESEPVSPVPKVTAQMLTEAIEHHG
PQTADELALMFGITSRRANSSLAMAISKGRLIRVNQGGKFRYCIPGADLPAEPKAASITETDGKAFPQPAGVALPVGEAE
TQEEIKTESVAVTVQSQPSFTRKHPDGLILPSLHVANRELRRAKGQVQKWERVCAALRELNKCRDILRDITATREQQR
>SEQF1516_EDU83441.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTITRERAEIKSYITGFLSDSAHDNKSSDSLLANVFRIALASLEAEPIAMVVPDEMDLLTCHLDGVTKTYADGWNACRV
AMLQAGNFRENKNSSTNNFREISETSTRSPITLDGWISCTERMPEKSQNVLISMNIDSEAGPLIYSARYLGGTFRRGGIA
VSPGNDLRQATHWMSLPEPPQEVNQ
>SEQF1516_EDU83442.1 protein YgiW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKVLIAALISGVSFGAFAQQGGFQGPEAERSTVAQAKELKDDAWVILEGSIVKKVGDERYEFRDNSGTIVTDIDDSVWA
GQNVSPKDKVRIEGEIDKDLSSVEVDVKALKLLK
>SEQF1516_EDU83443.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKILYQDYGPVGQVVISSTVMEFRKHNRVVDAVLLTCPGISASRAGVFIMKTKLYGSKAWIKKAYRVALQEVNSE
>SEQF1516_EDU83444.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEIKEMPVVRDGYGYWTHPEYEKFCDGREYISTEEFNAWMEENNLQYVLCFRDEGCADLDACDADISAWEPERPEGDGW
FIGSIHDTEDGPVCVWLRNKAEA
>SEQF1516_EDU83445.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAGFNFNNYAAGFCSATPALRGNEVNMDTLNLGNNESLVCGVFPNQDGTFTAMTYTKSKTFKTEAGARRWLARNTD
>SEQF1516_EDU83446.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVKSVGALIGRTEAAVRTKARELGISMMLRGDFHPSAKYSQRDIELARQLHQRGMQRREIARKLGMPLRIVNNYVYFDR
RVSA
>SEQF1516_EDU83447.1 primosomal protein 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYAVTPARLAELLALEEKLARPGSDVDLDDQLYQEPQAA
PVAVPMGKFAMYPDWQPDADFIRLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPK
RDVNTVSEPDSQIPPGFRG
>SEQF1516_EDU83448.1 transcriptional regulator, LuxR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPGCCKNGIVISKIPVMQAGLKEVMRTHFPEYEIISSASAEDLTLLQLRRSGLVIADLAGESEDPRSVCEHYYSLISQY
REIHWVFMVSRSWYSQAVELLMCPTATLLSDVEPIENLVKTVRSGNTHAERISAMLTSPAMTETHDFSYRSVILTLSERK
VLRLLGKGWGINQIASLLKKSNKTISAQKNSAMRRLAIHSNAEMYAWINSAQGARELNLPSVYGDAAEWNTAELRREMSH
S
>SEQF1516_EDU83449.1 transcriptional regulator, LuxR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGNPYKLHTYTSQESFQDAMSRISFAAVIFSFSAMRSERREGLSCLTEL
AIKFPRTRRLVIADDDIEARLIGSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREI
LRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCETSNVLHPY
>SEQF1516_EDU83450.1 DNA replication protein DnaC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAALERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEG
QMNALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSGTSEEQLLNDL
SNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVMDRMRLGNSLWVIFNWDSYRSRV
TGKEY
>SEQF1516_EDU83451.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILVIIINERDKTMLQRTLGSGWGVLLPGFLIAGLMYADLSPDQWRIVILMGLVLTPVMLYHKQLRHYILLPSCLALIAG
IMLMIMNLNQG
>SEQF1516_EDU83452.1 hypothetical protein ECH7EC4501_5609 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKSELSLAANKLSHEYYHYNEFYCFSLYGSEIIDSWGAFFSVNKLKSSDFIE
>SEQF1516_EDU83453.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEFLLALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGSIGHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYL
AHPKVFTVAAVIPMFPGISAYTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV
>SEQF1516_EDU83454.1 ferric iron reductase protein FhuF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYRSAPLYEDIIWRTHLQPQDARLAQAVRATIAEHREHLLEFIRLDEPAPLNAMTLAQWSSPNALSSLLAVYSDHIYRN
QPTMIREYKPLISLWAQWYIGLMVPPLMLALLTQEKALDVSPEHFHAEFHETGRVACFWVDVCEDKNATPHSPQQRMETL
ISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEKTLTTGEDNPLWRTVVLRDGLLV
RRTCCQRYRLPDVQQCGDCTLK
>SEQF1516_EDU83455.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTVKHLLCCAIAASALISTGVHAASWKDALSSAASELGNQNSTTQEGGWSLASLTNLLSSGNQALSADNMNNAAGILQY
CAKQKLASVTDVENIKNQVLEKLGLNSEEQKEDTNYLDGIQGLLKTKDGQQLNLDNIGTTPLAEKVKTKACDLVLKQGLN
FIS
>SEQF1516_EDU83456.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDSHYLNNTQHVYDKGRVMQTEQQRAVTRLCIQCGLFLLQHGAESALVDELSSRLGRALGMDSVESSISSNAIVLTTIKD
GQCLTSTRKNHDRGINMHVVTEVQHIVILAEHHLLDYKGVEKRFSQIQPLRYPRWLVALMVGLSCACFCKLNNGGWDGAV
ITFFASTTAMYIRQLLAQRHLHPQINFCLTAFAATTISGLLLQHPTFSNTPTIAMAASVLLLVPGFPLINAVADMFKGHI
NTGLARWAIASLLTLATCVGVVMALTIWGLRGWV
>SEQF1516_EDU83457.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKSTSCTTIDFMNMSQLTERTFTSSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWP
NLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMI
SMDKEGDSTILFRNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRL
QVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAI
QPQMATMFRG
>SEQF1516_EDU83458.1 hypothetical protein ECH7EC4501_0175 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLPKRLYYPLPEAAEKLGCAIKDLYHYAYIGALNISVYIPKIDAKKFNFSLCHFINGCNEEELIKYPFNDESAVFGSNF
TVGLTGDTEFLDSAIIGPVGNSIKCYYVSSLSGFYYTPAYVFADVEFSMRQYIKCSHLTNKYGDDNLMYVFCKGGYEFDV
NYLCVMASDLDNIKNTGDFPKITEDSPKASSKRNEVIYSLIKLIPEMGDVDLDTESLPKIADLIDSIAASRGIEFPKTHW
QTWQKYLGRESQQKRKK
>SEQF1516_EDU83459.1 site-specific recombinase, phage integrase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRAIHRLSDTLLRKLSGSPTTKNTFFNDGGNLSVRHSTNGLLTWYFTYRAGTGRQISPERLRLGNYPDLSLKAAREKAA
QCRAWLAEGKNPRYELNHAVQDALAPVTVKEALTYWLESYAKEKRTDYESLKSRINKHIISQIGAMPLEKCELRHWLACF
DQLAKRNPVSAGFLLQVCKQALKYCRKRRYAISNVLDDMVVGDVGKKAEISERVLTNKELGELLRALDEKIYPPYYSALI
RLLIVFGCRTTELRRSEVQEWDFKEMLWTVPKEHSKTKVAIFRPIPEAILPFVMKLVEQNRHTGLLLGELKGQSSVSEYG
RTAHRRINQAPWTLHDIRHTFTTMLNDLGVEPHVVEQLTAHQLPGMQRVYNHSRYLDAKRDALNLWVERLDVLAGNHENI
VMLKVAK
>SEQF1516_EDU83460.1 macrolide-specific ABC-type efflux carrier protein MacB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPLLELKDIRRSYPAGDEQVEVLKGITLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADAL
AQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALM
NGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNVAGGTEPV
VNTASGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDF
GDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQ
VVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGF
DSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFMTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMA
VGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLD
PVDALARE
>SEQF1516_EDU83461.1 cold shock domain protein CspD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>SEQF1516_EDU83462.1 macrolide-specific efflux protein MacA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKRKTVKKRYVITLVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIG
DKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSLQDLDTAATEMAVKQAQI
GTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPG
QKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGD
NRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>SEQF1516_EDU83463.1 aquaporin Z [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKE
VVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG
FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRN
>SEQF1516_EDU83464.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTF
RESLPGRHRVRRYRPLEACWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQAHHLVRLMPVLRLR
DARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNE
QRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIA
TTNSGELLSLTPVEHVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQC
GHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQ
GFSDVFHRVAQIPENVPMNLRKIISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>SEQF1516_EDU83465.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQNTQFQSLSDRVIREDECRKLTGVCRTTRYELEKKGRFPSRLNLGGRSVGWLLSEVMEWVKSRDRINSGKAV
>SEQF1516_EDU83466.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU83467.1 DNA methylase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRFIQGDCVRVMATIPGNGVDFILTDPPYLVGFRDRQGRTIAGDKTDEWLQPACNEMYRVLKKDALMVSFYGWNRVDRF
MAAWKNAGFSVVGHLVFTKTYTSKAAYVGYRHECAYILAKGRPALPQKPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESF
THPNAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAANDDWFMPEAA
>SEQF1516_EDU83468.1 hypothetical protein ECH7EC4501_6204 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCGCMPAVDCCCVLLIHNILRTVMWTKYLVTQAVPAR
>SEQF1516_EDU83469.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPAGSGKSARPVPGRTRDTDHRQRSCRAASAGAVKRGARRHPLPEKKRAVARPSPSYFIHRNAPPCRLSTPAR
>SEQF1516_EDU83470.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNENTTLNALICRHARNLLLAQGWPEETDVDQRNPKYPGWISIYVLLDAPRLATLLVNRHGGVLPPHLASAIQKLTGTGA
ELVLSGSQWQSLPVLPADGTQVSFPYAGEWLTEDEIRAVLAAVRDAVRSVSCRVAEDTRRIRAALTTTGQTLLTRQTRRF
RLVVKESDHPCWLDEDDENLPVVLDAILNRGARFSAVEMYLVSDCIEHILSSGLACDVLRIPDEPPRRWFDRGVLREVVR
EARNEIRSMADALAKIRK
>SEQF1516_EDU83471.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNYAGHEKLRADVAEVANTMCDLRARLNDMEHRCRFDSDVLVERLARQTLYRANRLFMEAYTEILELDACFKD
>SEQF1516_EDU83472.1 replication initiation protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDFRRRFLQVCVNEINSRTPMRLSYIEKKKGRQTTHIVFSFRDITSMTTG
>SEQF1516_EDU83473.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYGTCETLCRELAAKYPGYTPLMLVIWSPEEIQALADGMDISLSDPEIRTVLARLEDIPEDQRIESGISSAAAMEIISNV
SENRQVTVPAELLASLIQTAEQALWKREWAARDYGLAVPECVTRRQAVVNQARILLKNNTHENG
>SEQF1516_EDU83474.1 RNA-directed DNA polymerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEQATTCKGASLLNGDSWHSINWRQCYREVRRLQARIVKATREGKHGKVKSLQWILTHSFSGRAVAVRRVTENSGKRTP
GVDGQTWSSPEVKFLAINLLKRRGYKPQPLKRVYIPKSNGKSRPLGIPTMKDRAMQALYLLALEPVAEVTADQRSFGFRT
GRSTADAIAQCFCVLAQKTSAEWVLEGDIRGCFDNISHQWLIDNTSTDRQILTKWLKAGYREKGQLFPVNSGTPQGGIIS
PVLANIALDGLEALLASEFKKRTVKGRLVNPKVNYVRYADDFIITGESKELLESQVLPVVRRFMAERGLMLSPEKTKITH
IEEGFDFLGQNIRKYGGKMLIKPSKANVSSFLKKIRAVIKGNKAMDQLTLIRMLNPMIKGWAAYHQHIVAKVAFNKVDNE
IWLALWRWAVRRHPNKGKKWIRKRYFHQQGARNWSFSTATGELLANGKPQYANLRKAIDTPINRFKPIKIAANPFDPQWE
MYFEERCADKMRHKLQGRKKLIQIWFEQRGRCPICDERITSDSQWQVHHIIRRVDGGSNCLSNLIMLHPMCHTLVHAKGI
HVVKPAHESGLRKA
>SEQF1516_EDU83475.1 hypothetical protein ECH7EC4501_6201 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSVYALVKCFHEFHSEHPLIIALHFFIKSCNLLQSNNKIAKSSKNRKVV
>SEQF1516_EDU83476.1 w0052 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYFSGEPAQIAEIKRLASGAVTPLYRRATNEGIQLFLAGSAGLLQTTEDVRFEPCPGLTAAGRGVVSPENIAFTRWLTHL
QDGVLLDEQNCLMLHELWLQSGTGRRRWEELPDDARESITALFTPKRGDWCDIWSNEDVSVWWNRLCDNVLPEKTMPFDL
LTVLSTRLDVEVNGFNGGVLNGVPSAYHWYTEQYGVKWPCGYEVNISSQGDNFIQVDFDTPWCQPESDVIAVLSRRFSCM
LEHWYAGQGCNFCGWQRYERGELVDVLWGELEWSSPTDDDELPEVTAPEWIVDKVAHYGG
>SEQF1516_EDU83477.1 plasmid partition protein SopB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRAPVIPKHTLNTQPVEDTSLSTPAAPMVDSLIARVGVMARGNAITLPVCGRDVKFTLEVLRGDSVEKTSRVWSGNERD
QELLTEDALDDLIPSFLLTGQQTPAFGRRVSGVIEIADGSRRRKAAALTESDYRVLVGELDDEQMAALSRLGNDYRPTSA
YERGQRYASRLQNEFAGNISALADAENISRKIITRCINTAKLPKSVVALFSHPGELSARSGDALQKAFTDKEELLKQQAS
NLHEQKKAGVIFEAEEVITLLTSVLKTSSASRTSLSSRHQFAPGATVLYKGDKMVLNLDRSRVPTECIEKIEAILKELEK
PAP
>SEQF1516_EDU83478.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEYRSRRLFDGENMPRKRLEGRSSEKGDGLAYTVTDASRER
>SEQF1516_EDU83479.1 plasmid partition protein SopA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLMETLNQCINAGHEMTKAIAIAQFNDDSPEARKITRRWRIGEAADLVGVSSQAIRDAEKAGRLPHPDMEIRGRVEQRV
GYTIEQINHMRDVFGTRLRRAEDVFPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDL
HIHAEDTLLPFYLGEKDDVTYAIKPTCWPGLDIIPSCLALHRIETELMGKFDEGKLPTDPHLMLRLAIETVAHDYDVIVI
DSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQFFDMLRDLLKNVDLKGFEPDVRILLTKYSNSNGSQSPWMEEQIR
DAWGSMVLKNVVRETDEVGKGQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR
>SEQF1516_EDU83480.1 endonuclease/exonuclease/phosphatase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERIRILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQT
TPELVQFATANYLAADQVPAFVLPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTDDQRRRAFGRPLDFVFYRGLNVS
EASVLVTRASDHNPLLVEFSPGKPDK
>SEQF1516_EDU83481.1 membrane-bound lytic murein transglycosylase D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYMYWIAGQVKKRNMPMELVLLPIVES
AFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNYDARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAI
KTNKARGKSTDFWSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVADMAGISVSKLK
TFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVADNTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQ
QWNKLRGSKLKPGQSLTIGAGSSAQRLANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKN
NSMPDS
>SEQF1516_EDU83482.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMKLGVSLLNRTTRQLSLTEEGERYFRRVQSILQEMAAA
ESEIMETRNTPRGLLRIDAATPVVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
NSYRKIIASPDYISRYGKPETIDDLKQHVCLGFTEPASLNTWPVACSDGQLHEVKYGLSSNSGETLKQLCLSGNGIACLS
DYMIDREIARGELVELMADKVLPVEMPFSAVYYSDRAVSTRIRAFIDFLSEHVKTAPGGAVREA
>SEQF1516_EDU83483.1 2,5-didehydrogluconate reductase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIPAFGLGTFRLKDDVVISSVKTALELGYRAIDTAQIYDNEAAVGLAIAESGVPRHELYITTKIWIENLSKDKLIPSLK
ESLQKLRTDYVDLTLIHWPSPNDEVSVEEFMQALLEAKKEGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
NRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSVIPSSTKRENLESNLKAQNLQLD
AEDKKAIAALDCNDRLVSPEGLAPEWD
>SEQF1516_EDU83484.1 methyltransferase, UbiE/COQ5 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTQSHHDHVEKQFSSQASEYLTSTVHASGRDLQLLAVCLADYPDASVLDMGCGAGHASFVAAQNVSTVVAYDLSAQMLD
VVAQAAEVRQLKNITTRQGYAESLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDIWL
QTVEALCDTSHVRNYASGEWLRLINEANLIVDNLITDKLPLEFSSWVARMRTPEALVDAIRIYQQSASTEVRTYFALQND
GSFTSDIIMVDAHKAA
>SEQF1516_EDU83485.1 aspartate--ammonia ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGTQDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQT
LGQHDFSAGEGLYTHMKALRPDEDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPF
LPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDYDDWSTPSELGHAGLNGDILVWN
PVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLQLEWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPA
AVRESVPSLL
>SEQF1516_EDU83486.1 potassium uptake protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGVERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGE
GGILTLMSLAGRNTSARTTSMLVIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKH
GTAMVGKLFAPIMLTWFLILAGLGLRSIIANQEVLYALNPMWAVHFFLEYKTVSFIALGAVVLSITGVEALYADMGHFGK
FPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNPFFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGY
LSPMRIIHTSEMESGQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHWNKYFVALI
LIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRRMHEHGNSLEAMIASLEKSPPVRVPGTAVYM
SRAINVIPFALMHNLKHNKVLHERVILLTLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGL
SCRMMETSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI
>SEQF1516_EDU83487.1 ATPase family associated with various cellular activities [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAHPHLLAERISRLSSSLEKGLYERSHAIRLCLLAALSGESVFLLGPPGIAKSLIARRLKFAFQNARAFEYLMTRFSTPE
EVFGPLSIQALKDEGRYERLTSGYLPEAEIVFLDEIWKAGPAILNTLLTAINERQFRNGAHVEKIPMRLLVAASNELPEA
DSSLEALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPASLQVTDEEYERWQKEIGEITLPDHVFELIFMLRQQLD
KLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVDLILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIV
QRHLQLQQQQSDKTALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHNMEVVHISFERSALEQWLSKGGEIRGK
LNGIGFAQKLNLEVDSAQHLVVRDVSLQGSTLALPGSSAEGLPGEIKQQLEELESDWRKQHALFSEQQRCLFIPGDWLGR
IEASLQDVGAQIRQAQQC
>SEQF1516_EDU83488.1 cytoplasmic D-ribose-binding protein RbsD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKKMKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMALTQGVPSFMQVLGVVTNEMQVEAAIIAEEIKHH
NPQLHETLLTHLEQLQKHQGNTIEIRYTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF
>SEQF1516_EDU83489.1 ribose ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAG
IGIIHQELNLIPQLTIAENIFLGREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFES
KVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFESCDDVTVFRDGQFIAEREVASLTEDSLIEMMVGR
KLEDQYPHLDKAPGDIRLKVDNLCGPGVNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRS
PQDGLANGIVYISEDRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQAIGLLSGGN
QQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIILVSSEMPEVLGMSDRIIVMHEGHLSGEFTRE
QATQEVLMAAAVGKLNRVNQE
>SEQF1516_EDU83490.1 MioC protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDLSASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDL
SAVRFGAIGIGSREYDTFCGAIDKLEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWINLLK
>SEQF1516_EDU83491.1 ViaA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKAAITDDVPRWREALRSRLKDARVPPELTEEVMCYQQS
QLLSTPQFIVQLPQILDLLHRLNSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQ
ERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQLGRSREAKSIPRNDAQMETFRT
MVREPATVPEQVDGLQQSDDILRLLPPELATLGITELEYEFYRRLVEKQLLTYRLHGESWREKVIERPVVHKDYDEQPRG
PFIVCVDTSGSMGGFNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGGTDLASCFR
AIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVAMSAHGKPGIMRIFDHIWRFDTGMRSRLLRR
WRR
>SEQF1516_EDU83492.1 regulatory protein AsnC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVEKMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAK
DYPSALAKLESLDEVTEAYYTTGHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP
>SEQF1516_EDU83493.1 outer membrane receptor-mediated transport energizer protein TonB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIMTSMTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEP
EPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQQKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRA
LSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGT
TEIQ
>SEQF1516_EDU83494.1 oligopeptide ABC transporter, ATP-binding protein OppD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVIETATVPLAQQQADALLNVKDLRVTFSTPDGDVTAVNDLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIG
GSATFNGREILNLPERELNKLRAEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKNMSKAEAFEESVRMLDAVKMPEARK
RMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVL
VMYAGRTMEYGNARDVFYQPVHPYSIGLLNAVPRLDAEGETMLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAPPLEE
FTPGRLRACFKPVEELL
>SEQF1516_EDU83495.1 cardiolipin synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLIIYILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAK
WLNDLKACKHIFAEENSSVAAPLFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQ
VAESLMAAARRGIHCRLMLDSAGSVAFFHSPWPELMRNAGIEVVEALKVNLMRVFLRRMDLRQHRKMIMIDNYIAYTGSM
NMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIYSCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPED
LIHQALLTAAYSAREYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAGVKVYQFEG
GLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQDDYISRSRLLDARLWLKRPLWQRVAERLFY
FFSPLL
>SEQF1516_EDU83496.1 potassium channel protein kch [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLRHDILALAVFLNGLLIFKTIYGMSVNLLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIIL
LLIALIYTLHFYPWLKFSIGFCIFTLVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALYLSEGFNPRIESLMTA
FYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMTSIFGPLIRGGFNKLVKGNNHTMHRKDHFIVCGHSILA
INTILQLNQRGQNVTVISNLPEDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKDM
SSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLLNSGHGIFSDNDEQETKADSKESA
QK
>SEQF1516_EDU83497.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEERGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADS
EDGEINDVFARILLCREKDHKLCHIIWRE
>SEQF1516_EDU83498.1 oligopeptide ABC transporter, permease protein OppC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMES
GHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF
GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTSGIVIRHIVPNVLGVVVVYASLLVPSMILFESFL
SFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKDR
>SEQF1516_EDU83499.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGRWRMQRQASRRKSRWLEGQSRRNMRIHSIRKCILNKQRNSLLFAIYNI
>SEQF1516_EDU83500.1 hypothetical protein ECH7EC4501_5703, partial [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
NNNQLLNYCAFHYWNCNQKRSTCLTNLYLIEFKDVC
>SEQF1516_EDU83501.1 oligopeptide ABC transporter, permease protein OppB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPEVMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFK
YKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGLAMTGVVIPSFVVAPLLVMIFAIILHW
LPGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRIILRHALKPALLPVLSYMGPAF
VGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVIDPKIRY
>SEQF1516_EDU83502.1 YciL domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYVIYAQDKADSLEKRLSVRPAHLARLQLLHDEGRLLTAGPMPAVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPY
VAAGVYEHVSVKPFKKVF
>SEQF1516_EDU83503.1 oligopeptide ABC transporter, ATP-binding protein OppF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAVTEGRKVLLEIADLKVHFEIKDGKQWFWQPPKTLKAVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGH
VAWLGKELLGMKPDEWRAVRSDIQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKMSRQEVRERVKAMMLKVGLLPNLINR
YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYL
GHAVELGTYDEVYHNPLHPYTRALMSAVPIPDPDLEKNKTIQLLEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVLEG
SFRHAVSCLKVDPL
>SEQF1516_EDU83504.1 oligopeptide ABC transporter, periplasmic oligopeptide-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLVNTSNYNEGVQKTMTNITKRSLVAAGVLAALMAGNVALAADVPAGVTLAEKQTLVRNNGSEVQSLDPHKIEGVPESNI
SRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHLRKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIA
GIDEILEGKKPITDLGVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYTLKDWVVN
ERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTYNNMPIELFQKLKKEIPDEVHVDPYLCTYYYEINN
QKPPFNDVRVRTALKLGMDRDIIVNKVKAQGDMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPL
TINLLYNTSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPTSFLNTMLSNSSMNTA
HYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPVYYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH
>SEQF1516_EDU83505.1 RNA methyltransferase, TrmH family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPGKSRADGGRRPARDDKQSQPRDRKWEDSPWRTVSRAPGDET
PEKADHGGISGKSFIDPEVLRRQRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEA
ELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSCAHFGVKGVVVQDAALLESGAAI
RTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTSSEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGT
GNVAGLNISVATGVLLGEWWRQNKA
>SEQF1516_EDU83506.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLHSKFDIFDRFGVMDLRRFITLKTVVEEGSFLRASQKLCCTQSTVTFHIQQLEQEFSVQLFEKIGRRMCLTREGKKLL
PHIYELTRVMDTLREAAKKESDPDGELRVVSGETLLSYRMPQVLQRFRQRAPKVRLSLQSLNCYVIRDALLNDEADVGVF
YRVGNDDALNRRELGEQSLVLVASPQIADVDFTEPGRHNACSFIINEPQCVFRQIFESTLRQRRITVENTIELLSIESIK
RCVAANIGVSYLPRFAVEKELESGELIELPFGEHSQTITAMCAHHAGKAVSPAMHTFIQCVEDCFLPG
>SEQF1516_EDU83507.1 putative methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAGVKRCLDIGAGSGLLALMLAQRTSDSVIIDAVELESE
AATQAQENVAQSPWLERINVHTADIQQWVTQQTARFDLIISNPPYYEQGVECATPQREQARYTTSLDHQTLLTCAAECIT
EEGFFCVVLPEQIGNSFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFSDRLVIRGPDQNYSEAYTALTQA
FYLFM
>SEQF1516_EDU83508.1 uracil-DNA glycosylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDVFNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVR
PGIATPPSLLNMYKELENTIPGFTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
FLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQHGETPIDWMPVLPAESE
>SEQF1516_EDU83509.1 autonomous glycyl radical cofactor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVVAVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRR
ETLEDAVKHPEKYPQLTIRVSGYAVRFNSLTPEQQRDVIARTFTESL
>SEQF1516_EDU83510.1 L-aspartate oxidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTLLEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEGSTFYAQGGIAAVFDETDSIDSHVEDTLIAGAGICDR
HAVEFVASNARSCVQWLIDQGVLFDTHIQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVSKALNHPNIRVLERS
NAVDLIISDKIGLPGTRRVVGAWVWNRNKEKVETCHAKAVVLATGGASKVYQYTTNPDISSGDGIAMAWRAGCRVANLEF
NQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTRFMPDFDVRGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADF
IRQHFPMIYEKLLGLGIDLTQEPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSLLECLVYGW
SAAEDITRRMPYAHDISTLPPWDESRVENPDERVIIQHNWHELRLFMWDYVGIVRTTKRLERALRRITMLQQEIDEYYAH
FRVSNNLLELRNLVQVAELIVRCAMMRKESRGLHFTLDYPELLTHSGPSILSPGNHYINR
>SEQF1516_EDU83511.1 translocator protein, LysE family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPTLLSAFWTYTLITAMTPGPNNILALSSATTHGFHQSTRVLAGMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGA
AYIVWLAWKIATSPTKEDGLQTKPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWIVGVSVLLAMIGTFGNVCW
ALAGHLFQRLFRQYGRQLNIVLALLLIYCAVRIFY
>SEQF1516_EDU83512.1 ATP-dependent RNA helicase SrmB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVTTFSELELDESLLEALQDKGFTRPTAIQAAAIPPALDGRDVLGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRIL
ILTPTRELAMQVADHARELAKHTHLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEAD
RMLDMGFAQDIEHIAGETRWRKQTLLFSATLEGDAIQDFAERLLEDPVEVSANPSTRERKKIHQWYYRADDLEHKTALLV
HLLKQPEATRSIVFVRKRERVHELANWLREAGINNCYLEGEMVQGKRNEAIKRLTEGRVNVLVATDVAARGIDIPDVSHV
FNFDMPRSGDTYLHRIGRTARAGRKGTAISLVEAHDHLLLGKVGRYIEEPIKARVIDELRPKTRAPSEKQTGKPSKKVLA
KRAEKKKAKEKEKPRVKKRHRDTKNIGKRRKPSGTGVPPQTTEE
>SEQF1516_EDU83513.1 DTW domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTENAVLQLRAERIARATRPFLARGNRVRRCQRCLLPEKLCLCSTITPAQAKSRFCLLMFDTEPMKPSNTGRLIADILPD
TVAFQWSRTEPSQDLLDLVQNPDYQPMVVFPASYADEQREVIFTPPAGKPPLFIMLDGTWPEARKMFRKSPYLDNLPVIS
VDLSRLSAYRLREAQAEGQYCTAEVAIALLDMAGDTGAAAGLGEHFTRFKTRYLAGKTQHLGSITAEQLESV
>SEQF1516_EDU83514.1 putative thioredoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTVCTHCQAINRIPDDRIEDAAKCGRCGHDLFDGEVINATGETLDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAQE
RSGKVRFVKVNTEAERELSSRFGIRSIPTIMIFKNGQVVDMLNGAVPKAPFDSWLNESL
>SEQF1516_EDU83515.1 CI protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDGSSTERNNKDMKMKWYELARSRMKELGITQEKLAEELGMTQGGIGHWLRGSRHPSLSDIGVVFKYLGIDNISFNHDGT
FSPVGEYSSAPVKKQYEYPVFSHVQAGMFSPELRTFTKGDAERLVSTTKKASDSAFWLEVEGNSMTAPTGSKPSFPDGML
ILVDPEQAVEPGDFCIARLGGDEFTFKKLIRDSGQVFLQPLNPQYPMIPCNESCSVVGKVIASQWPEETFG
>SEQF1516_EDU83516.1 NinB family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCGAMQNVTSVKPGGHGHHQLLRRLKNGTGEQEMKQTFLLRNEAIRNNAIDAILSLPIDDKSPHEVHVKEPKRSKAQNDR
MWPMLNDVSRQVLWHGQRLAPEDWKDLFTALWLKTKKLEQRSVPGIDGGVVMLGVRTSKMRKASMTELIEIMFWFGSERN
VRWSDDSRREYEWSQRKGRAA
>SEQF1516_EDU83517.1 DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNELINSNAIKMTSIEIAELVGSRHDKVKQSIERLAVRGVIRNPPMVVFEKINNLGLLRGVEAYVFEGEQGKRDSIIVVA
QLSPEFTARLVDRWRELEGATAKIPQTFSEALRLAADLEDQKAELEKQLALAAPKVEFADRVGEASGILIGNFAKVVGIG
PNKLFAWMRDHKILIASGSRRNVPMQEYMDRGYFTVKETAVNTNHGIQISFTTKITGRGQQWLTRKLLDNGMLKVTREAA
>SEQF1516_EDU83518.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKQLSPYQDKIHKHILRDRFLSSFKQPGRFRAELEKVKLMQKEKGHE
>SEQF1516_EDU83519.1 shiga toxin 2 B subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKMFMAVLFALASVNAMAADCAKGKIEFSKYNEDDTFTVKVDGKEYWTSRWNLQPLLQSAQLTGMTVTIKSSTCESGSG
FAEVQFNND
>SEQF1516_EDU83520.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGEREVNDSYRQFENWWSKDKSQFTGDDELKEFAWVIWQASRSAIELDIDWPESNDDFWKDGEEGAYAMGYEDGRDKTVI
AVMKAIRAAGIKEKNFD
>SEQF1516_EDU83521.1 replicative DNA helicase homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDNFYAPPHSIEAEQAVIGGLLLDDDSSERVQKVLAMLKPDSFYSRPHKIIFEEITRMHREQKPVDGLTLFDELERKSL
TASVGGFAYIAEIAKNTPSAANIVAYAMQVRETAMERYAINRMTEATELLYSRNGMTATQKYEAIQAIFTQLTDHAKTGS
RRGLRSFGEVMEDWVSDLEKRFDPSGEQRGMSTGIPSLDRMLSPKGLVKGSLFVIGARPKMGKTTLYSQMAINCAVHEKK
PALMFSLEMPGDQILEKLVGQKSGVNPNIFYLPATNDADDGYQGDYDGDFNRAIETANRLSEIDLLYIDDTPGLSLAQIV
SESRRIKREKGCVGMILVDYLTLMTAEKADRNDLAYGMITKGLKNLAKELDCVVVLLTQLNRALESRTNKRPLPSDSRDT
GQIEQDCDYWVGIHREGAFDDSVPPGETELILRLNRHGNTGTVYCIQANGAIYDTDQQSAEMRRREREEPQSKKKGGF
>SEQF1516_EDU83522.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKKQLAILEKAWDAQISYALKEQALPIIQTKSKIARQLCDGGFLNEIEITRQMVTFKGYEINHHGIAAYCSHLPDDVDI
DEMEREMKQ
>SEQF1516_EDU83523.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTIAELVRANFREELVRWYRYRSSSSLPLDELYEHSPAARRYPRDRVLRRLFKLNNEFQRNRIIRSLDLK
>SEQF1516_EDU83524.1 bacteriophage CII protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQTSYSKLSQREIDRAETDLLINLSTLTQRGLAKMIGCHESKISRTDWRFIASVLCAFGMASDISPISRAFKYALDEIT
KKKSPAATEDFKQIDMQF
>SEQF1516_EDU83525.1 putative replication protein O [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNISNLAEAREARRLQQPHQSSGKGYALLHRKIMDVPFYKDAEAAHLWVHLILKAKHTPEYVMTDAGEILVGRGKLLGG
RNSLAFETGLKPDRVQYLLRKFKKLGMIDWVSHGKFSVFSVEKYDDYQSNFVPADYQQITTSKPAIPMPASNTVPADYQQ
ITTDKEYNNIISNTDVLESATADKKSDKKKPSVSCQDVVDAYHEILPEAPKIRALNDKRKNQIRTFWRKAGVITRQLDGH
GFTMQDWRNYLSYVGENCRWMFEERPNHQRGTVWHKKGFDFLLNDNTYLKVREGEHDDR
>SEQF1516_EDU83526.1 hypothetical protein ECH7EC4501_2326 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSVLYGRVRQVKKRPAINKNQVHPLSGQMENLLDAKRYEITPV
>SEQF1516_EDU83527.1 shiga toxin subunit A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVINHTPPGSYFAVDIRGLDVYQARFDHLRLIIEQNNLYVAGFVNTATNTFYRFSDFTHISVPGVTTVSMTTDSSYTTL
QRVAALERSGMQISRHSLVSSYLALMEFSGNTMTRDASRAVLRFVTVTAEALRFRQIQREFRQALSETAPVYTMTPGDVD
LTLNWGRISNVLPEYRGEDGVRVGRISFNNISAILGTVAVILNCHHQGARSVRAVNEESQPECQITGDRPVIKINNTLWE
SNTAAAFLNRKSQFLYTTGK
>SEQF1516_EDU83528.1 phage N-6-adenine-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIKSNTPAHDKDCWQTPLWLFDALDIEFGFWLDSAASDKNALCAHWLTEADDALNSEWVSHGAIWNNPPYSNIRPWVEK
AAEQCIQQRQTVVMLVPEDMSVGWFSKALESVDEVRIITDGRINFIEPSTGLEKKGNSKGSMLLIWRPFISPRRMFTTVS
KAALMAIGQGVRRAA
>SEQF1516_EDU83529.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTQISVETLSPITHNQIPVITTELLAQLYGTEPVRIRQNHHENKVRFVEGKHFFKVVGNDLKELRVALNYSQNLRVTLS
NSQNLQPSLRGLQISPKARSLILWTERGAARHAKMLETDQAWDVFEKLEDCYFSQCEKNTGKQEKKLNGLSAKETDSLVW
LWDYANRSQALFRELYPALKLIQSGYSGICHDYGYEFSYIIGRARGVLINHTRDIDIYEPDGPTNLLAWERLKNKELPPS
LHRY
>SEQF1516_EDU83530.1 bacteriophage Lambda NinG protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKPARRKCKICKEWFHPAFSNQWWCCPEHGTQLALERRSKEREKAEKAAEKKRRREEQKQKDKLKIRKLALKPRSYWIK
QAQQAVNAFIRERDRDLPCISCGTLTSAQWDAGHYRTTAAAPQLRFDERNIHKQCVVCNQHKSGNLVPYRVELINRIGQE
AVDEIESNHNRHRWTVEECRAIKAKYQQKLKDLRNSRSEAA
>SEQF1516_EDU83531.1 Q protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRDIRQVLERWGAWAANNYEDVTWSPIAAGFKGLIPEKVKSRPQCCDDDAMVICGCIARLYRNNRDLHDLLVDYYVLGET
FMALARKHGCSDTCIGKRLHKAEGIVEGMLMMLGVRLEMDRYVERELPGGRTSVFYQRKNSLRS
>SEQF1516_EDU83532.1 protein Smg [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFDREDIYNALLWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECER
LDASCRGFLLFLEQIQVLNLETREMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH
>SEQF1516_EDU83533.1 large conductance mechanosensitive channel protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQ
NVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPTKEEVLLTEIRDLLKEQNNRS
>SEQF1516_EDU83534.1 ribosomal protein S13p [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARIAGINIPDHKHAVIALTSIYGVGKTRSKAILAAAGIAEDVKISELSEGQIDTLRDEVAKFVVEGDLRREISMSIKRL
MDLGCYRGLRHRRGLPVRGQRTKTNARTRKGPRKPIKK
>SEQF1516_EDU83535.1 ribosomal protein L17 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKELRRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLF
NELGPRFASRAGGYTRILKCGFRAGDNAPMAYIELVDRSEKAEAAAE
>SEQF1516_EDU83536.1 Zn(II)-responsive transcriptional regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESDLQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQ
ESKGIVQERLQEVEARIAELQSMQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC
>SEQF1516_EDU83537.1 ribosomal RNA small subunit methyltransferase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALLQELCFGVLRTLSQLDWLINKSMARPMTGKQRTVHYL
IMVGLYQLLYTRIPPHAALAETVEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNTSDARYLHPSWLLKRLQKAYPEQ
WQSIVEANNQRPPMWLRINRTHHSRDTWLALLDEAGMKGFPHADYPDAVRLETPAPVHALPGFEDGWVTVQDASAQGCMT
WLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAVDIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRIL
LDAPCSATGVIRRHPDIKWLRRDRDIPELAQLQSEILDAIWPHLKSGGTLVYATCSVLPEENSLQIKAFLQRTADAELCE
TGTPEQPGKQNLPGAEEGDGFFYAKLIKK
>SEQF1516_EDU83538.1 topoisomerase DNA-binding C4 zinc finger domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKSALFTVRNNESCPKCGAELVIRSGKHGPFLGCSQYPACDYVRPLKSSADGHIVKVLEGQVCPACGANLVLRQGRFGM
FIGCINYPECEHTELIDKPDETAITCPQCRTGHLVQRRSRYGKTFHSCDRYPECQFAINFKPIAGECPECHYPLLIEKKT
AQGVKHFCASKQCGKPVSAE
>SEQF1516_EDU83539.1 peptide deformylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQVDIHQRIIVIDVSENRDERLVLINPELLE
KSGETGIEEGCLSIPEQRALVPRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVE
KLDRLKARA
>SEQF1516_EDU83540.1 ribosomal protein L36 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG
>SEQF1516_EDU83541.1 ribosomal protein S11 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGWATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIK
NLEVMVKGPGPGRESTIRALNAAGFRITNITDVTPIPHNGCRPPKKRRV
>SEQF1516_EDU83542.1 DNA-directed RNA polymerase, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILE
ILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIH
SEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLRDVRQP
EVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIHYIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLEN
WPPASIADE
>SEQF1516_EDU83543.1 Trk system potassium uptake protein TrkA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFDLRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNM
VACQVAYSLFNTPNRIARIRSPDYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKA
YYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHIRAVMSELQRLEKPYKRIMLVGG
GNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQNTIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKR
MGAKKVMVLIQRRAYVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTSRVVGRVID
EIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERLFQPSPFFL
>SEQF1516_EDU83544.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWLLDQWAERHIAEAQAKGEFDNLAGSGEPLILDDDSHVPPELRAGYRLLKNAGCLPPELEQRREAIQLLDILKGIRHDD
PQYQEVSRRLSLLELKLRQAGLSTDFLRGDYADKLLNKINDN
>SEQF1516_EDU83545.1 ribosomal protein S4 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGARKPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAA
RLKGNTGENLLALLEGRLDNVVYRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALE
LAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK
>SEQF1516_EDU83546.1 methionyl-tRNA formyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRGKKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVAD
LQADVMVVVAYGLILPKAVLEMPRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPIT
AEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWSLSAAQLERCIRAFNPWPMSWVE
IEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVATGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV
>SEQF1516_EDU83547.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGRKWANIVAKKTAKDGATSKIYAKFGVEIYAAAKQGEPDPELNTSLKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFV
QGRYEGFGPNGSMIIAETLTSNVNRTIANVRTIFNKKGGNIGAAGSVSYMFDNTGVIVFKGSDPDHIFEILLEAEVDVRD
VTEEEGNIVIYTEPTDLHKGIAALKAAGISEFSTTELEMIAQSEVELSPEDLEIFEGLVDALEDDDDVQKVYHNVANL
>SEQF1516_EDU83548.1 shikimate transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDSTLISTRPDERTVSLSRARRAALGSFAGAVVDWYDFLLYGITAALVFNREFFPQVSPAMGTLAAFATFGVGFLFRPLG
GVIFGHFGDRLGRKRMLMLTVWMMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFAVGGEWGGAALLSVESAPKNKKA
FYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWGWRIPFLFSIVLVLGALWVRNGMEESAEFEQQQYNQAAAKKRIP
VIEALLRHPGAFLKIIALRLCELLTMYIVTAFALNYSTQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRRVYI
TGALIGTLSAFPFFMALEAQSIFWIVFFSIMLANIAHDMVVCVQQPMFTEMFGASYRYSGAGVGYQVASVVGGGFTPFIA
AALITYFAGNWHSVAIYLLAGCLISAMTALLMKDNQRA
>SEQF1516_EDU83549.1 AMP nucleosidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNKGSGLTPAQALDKLDALYEQSVVALRNAIGNYITSGELPDENARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHA
GSYTTTITRPTLFRSYLNEQLTLLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYFPTTELAQIGDETAD
GIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGCSQILDPDSPYIALSCAGGNWIT
AETEAPEEAISDLAWKKHQMPAWHLITADGQGITLVNIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVL
AHAYLRDDHVLDAVLPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDRNWELRYSASALRFNLSRAV
AIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAISEHLQIGIRAIDLLRAEGDRLHSRKLRTFNE
PPFR
>SEQF1516_EDU83550.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLVSLLRRIAFSYYDYKAYNFNIEKTDFVVIHIPDQIGDAMAIFPVIRALELHKIKHLLIVTSTINLEVFNALKLEQTK
LTLVTMTMQDHATLKEIKDLAKNITQQYGTPDLCIEAMRKKNLKTMLFISQLKAKTNFQVVGLTMKCYSPVCKNASRMDQ
KLRAPVPMTWAFMMREAGFPAVRPIYELPLSEDVLDEVREEMRSLGSYIALNLEGSSQDRTFSLSIAENLIEKIQSETDI
PIVIVHGPKGEDKARVLVDCYNNVYRLSLSPSIKRSAAIIKDAYIAITPDTSILHMASAYNTPVVAIYADYKTRWPAMAD
VSESVVVGQKIDNISLDEFAKALKSVLARI
>SEQF1516_EDU83551.1 hypothetical protein ECH7EC4501_5100 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLSRLYRETIRNCHFVFGNQKKKTWNFNKYYFSGNGDFL
>SEQF1516_EDU83552.1 acetyl-CoA carboxylase, carboxyl transferase, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLREKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVR
LAFDEFDELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
IDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKS
ADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAHRNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA
>SEQF1516_EDU83553.1 DNA polymerase III, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDFTNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDE
LTHLTVLAANNTGYQNLTLLISKAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
HFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVAIHDGFTLDDPKRPRNYSPQQYM
RSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEYFLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERVKRRPE
YDERLETELQVINQMGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFLNPERVSMP
DFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLGHPYGFVDRISKLIPPDPGMTLAKAFEAEPQ
LPEIYEADEEVKALIDMARKLEGVTRNAGKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLR
TLTIINWALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQPDCFEDMIALVALFRP
GPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYGIILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEM
AKQRSVFAEGAEKNGINAELAMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVVGL
VDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKGGYFRELFDLCARTDTKKLNRRVLE
KLIMSGAFDRLGPHRAALMNSLGDALKAADQHAKAEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLY
LTGHPINQYLKEIERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVMLFTDALDKYQH
LLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISLTDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQ
RADARARLRFGATWRVSPSDRLLNDLRGLIGSEQVELEFD
>SEQF1516_EDU83554.1 tRNA(Ile)-lysidine synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLTLNRQLLTSRQILVAFSGGLDSTVLLHQLVQWRTENPGGALRAIHVHHGLSANADAWVTHCENVCQQWQVPLVVERV
QLAQEGLGIEAQARQARYQAFARTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTR
GELAQWALAHGLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAETTARSAALCAEQESLLDELLADDLAHCQSPQGT
LQIVPMLAMSDARRAAIIRRWLAGQNAPMPSRDALVRIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVTGQSENI
VPWQTWLQPLELPAGQGSVQLNAGGDIRPPRADEAVSVRFKAPGLLHIVGRNGGRKLKKIWQELGVPPWLRDTTPLLFYG
ETLIAAAGGFVTQEGVAEGENGISFVWQRNA
>SEQF1516_EDU83555.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALSEAVREKAAYAAANLLVSDYVNE
>SEQF1516_EDU83556.1 lipid-A-disaccharide synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGPRMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRA
DLTKRFGELKPDVFVGIDAPDFNIILEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
CRFIGHTMADAMPLDPDKNSARDVLGIPYDAHCLALLPGSRGAEVEMLSADFLKTAQLLRQTYPDLEIVVPLVNAKRREQ
FERIKAAVAPDLSVHLLDGMGREAMVASDAALLASGTAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAG
RELVKELLQEECEPQKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ
>SEQF1516_EDU83557.1 ribonuclease HII [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLNDSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDE
LNILHATMLAMQRAVAGLHIAPEYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS
>SEQF1516_EDU83558.1 peptidyl-tRNA hydrolase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVISRHVAIPDGELEITAIRAQGAGGQHVNKTSTAIHLRFDIRASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQ
ELNREAALARLVAVIKDLTTEQKARRPTRPTRASKERRLASKAQKSSVKAMRSGRE
>SEQF1516_EDU83559.1 glyoxylase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLGLKQVHHIAIIATDYAVSKAFYCDILGFTLQSEVYREARDSWKGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLA
FSVDDIDAAVAHLESHNVKCEAIRVDPYTQKRFTFFNDPDGLPLELYEQ
>SEQF1516_EDU83560.1 acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVLKSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGE
PTRVEIGDRNRIRESVTIHRGTVQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMAAVH
QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNAYKLIYRSGKTLDEVKPEIAELA
ETYPEVKAFTDFFARSTRGLIR
>SEQF1516_EDU83561.1 lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLKFIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLY
AFINTHSTMDVSVQDMRMALCFFEYALGQAEDIAIRMRQYTDEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTNGTSTSNKIVGMYAAPSGSTLLI
DRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIPRREFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQ
TLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEAFMMHTTTS
PSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWFFDIWQPPQVDEAECWPVAPGEQWHGFNDAD
ADHMFLDPVKVTILTPGMDEQGNMSEEGIPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSY
DLNLRIKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAWQRQIKGEVETIALEQL
VGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSVGQHYPGFETDIHGAKQDEDGVYRVRVLKMAG
>SEQF1516_EDU83562.1 rof protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSMNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASDLVSRKNVEYLVVEAAGETRELRLDKITSFSHPEIGT
VVVSES
>SEQF1516_EDU83563.1 hypothetical protein ECH7EC4501_4184 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIYYLGYDRFLLIFFTDYSHFMDRITLPSTDTARGKGKWKIITA
>SEQF1516_EDU83564.1 K+-transporting ATPase, A subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAQGFLLIATFLLVLMVLARPLGSGLAWLINDIPLPGTTGVERVLFSALGVSNHEMNWKQYLCAILGLNMLGLAVLFFM
LLGQHYLPLNPQQLPGLSWDLALNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
STLGNAWVDLLRITLWVLVPVALVIALFFIQQGALQNFLPYQAVNTVEGAQQLLPMGPVASQEAIKMLGTNGGGFFNANS
SHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGDRRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINM
EGKESRFGVLVSSLFAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVFIAGLMIGR
TPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGPHGFSEVLYAVSSAANNNGSAFAGLSANSPF
WNCLLAFCMFVGRFGVIIPVMAIAGSLVSKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS
>SEQF1516_EDU83565.1 ornithine decarboxylase, inducible [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKMSELKIAVSRSCPDCFSTHRACVNIDESNYIDVAAIILSVSDVERGKLDEIDATGYDIPVFIATENEERIPAEYLSR
ISGVFEHGEARKEFYGRQLETAASHYETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEALFRA
DLCNADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGA
TPVYLETARNPYGFIGGIDAHCFEESYLRELITEVAPQRAKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFD
SAWVGYEQFIPMMADCSPLLLDLNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSP
FYPLFAALDINAKMHEGVSGRNMWMDCVVNGINARKLILDNCQHIRPFIPELVDGKPWQSYETAQIAVDLRFFQFVPGEH
WHSFEGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVA
LLVRFEKLLESDAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLR
GEVELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVI
KPRDAQSTLLKGEKL
>SEQF1516_EDU83566.1 K+-transporting ATPase, C subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRGLRPALSTFIFLLLITGGVYPLLTTALGQWWFPWQANGSLIREGDTVRGSALIGQNFTDNGYFHGRPSATAEMPYNPQ
ASGGSNLAVSNPELDKLIAARVAALRAANPNASTSVPVELVTASASGLDNNITPQAAAWQIPRVAKARNLSVEQLTQLIA
KYSQQPLVKYIGQPVVNIVELNLALDKLDE
>SEQF1516_EDU83567.1 KDP operon transcriptional regulatory protein KdpE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATAAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPSHFITETGIGYRFML
>SEQF1516_EDU83568.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELYREYPAWLIFLRRTYAVAAGVLALPFMLFWKDRARFYSYLHRVWSKTSDKPVWMDQAEKATGDFY
>SEQF1516_EDU83569.1 sensor protein KdpD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNEPLRPDPDRLLEQTAAPHRGKLKVFFGACAGVGKTWAMLAEAQRLRAQGLDIVVGVVETHGRKDTAAMLEGLAVLPP
KRLAYRGRHISEFDLDAALARRPALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGI
QVRETVPDPFFDAADDVVLVDLPPDDLRQRLKEGKVYIAGQAERAIEHFFRKGNLIALRKLALRRTADRVDEQMRAWRGH
PGEEKVWHTRDAILLCIGHNTGSEKLVRAAARLASRLGSVWHAVYVETPALHRLPEKKRRAILSALRLAQELGAETATLS
DPAEEKAVVRYAREHNLGKIILGRPASRRWWRRETFADRLARIAPDLDQVLVALDEPPARTINNAPDSRSFKDKWRVQIQ
GCVVAAALCAVITLIAMQWLMAFDAANLVMLYLLGVVVVALFYGRWPSVVATVINVVSFDLFFIAPRGTLAVSDVQYLLT
FAVMLTVGLVIGNLTAGVRYQARVARYREQRTRHLYEMSKALAVGRSPQDIAATSEQFIASTFHARSQVLLPDDNGKLQP
LTHPQGMTPWDDAIAQWSFDKGLPAGAGTDTLPGVPYQILPLKSGEKTYGLVVVEPGNLRQLMIPEQQRLLETFTLLVAN
ALERLTLTASEEQARMASEREQIRNALLAALSHDLRTPLTVLFGQAEILTLDLASEGSPHARQASEIRQHVLNTTRLVNN
LLDMARIQSGGFNLKKEWLTLEEVVGSALQMLEPGLSSPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAEIG
IDAHVEGENLQLDVWDNGPGLPPGQEQTIFDKFARGNKESAVPGVGLGLAICRAIVDVHGGTITAFNRPEGGACFRVTLP
QQTAPELEEFHEDM
>SEQF1516_EDU83570.1 K+-transporting ATPase, B subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSLLTTCISIAMASGAMPGNALFSVAISGWLWVTVLFAN
FAEALAEGRSKAQANSLKGVKKTAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITG
ESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNEIALTILLIALTIVFLLATATLW
PFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGVAGMSRMLGANVVATSGRAVEAAGDVDVLLLDKTGTITLGNRQAS
EFIPAQGVDEKTLADAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRMIRKGSVDA
IRRHVEANGGHFPADVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVKGGIKERFAQLRKMGIKTVMITGDNRLTAAA
IAAEAGVDDFLAEATPEAKLALIRQYQAEGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIE
VVHIGKQMLMTRGSLTTFSIANDVAKYFAIIPAAFAVTYPQLNALNIMRLHSPDSAILSAVIFNALIIVFLIPLALKGVS
YKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
>SEQF1516_EDU83571.1 putrescine-ornithine antiporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQAKSNKMGVVQLTILTMVNMMGSGIIMLPTKLAEVGTISIISWLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAF
GKSGNFMANYTYGVSLLIANVAIAISAVGYGTELLGASLSPVQIGLATIGVLWICTVANFGGARITGQISSITVWGVIIP
VVGLCIIGWFWFSPTLYVDSWNPHHAPFFSAVGSSIAMTLWAFLGLESACANTDVVENPERNVPIAVLGGTLGAAVIYIV
STNVIAGIVPNMELANSTAPFGLAFAQMFTPEVGKVIMALMVMSCCGSLLGWQFTIAQVFKSSSDEGYFPKIFSHVTKVD
APVQGMLTIVIIQSGLALMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQKVANVPPSKAKVANFVAFVGAMYSF
YALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG
>SEQF1516_EDU83572.1 hypothetical protein ECH7EC4501_4191 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSFEYIENRQRKRWRFFVSGRCSEEYLDTVIPIETYIHEIYINIFLIVSI
>SEQF1516_EDU83573.1 phosphoglucomutase, alpha-D-glucose phosphate-specific [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGTSGHRGSAARHSFNEPHILAIAQAIAEERAKNGITGP
CYVGKDTHALSEPAFISVLEVLAANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
NGGPADTNVTKVVEDRANALMADGLKGVKRISLDEAMASGHVKEQDLVQPFVEGLADIVDMAAIQKAGLTLGVDPLGGSG
IEYWKRIGEYYNLNLTIVNDQVDQTFRFMHLDKDGAIRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMN
PNHYLAVAINYLFQHRPQWGKAVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEESAGASFLRF
DGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAKRFGAPSYNRLQAAATSAQKAALSKLSPEMVSASTLAGDPITA
RLTAAPGNGASIGGLKVMTDNGWFAARPSGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA
>SEQF1516_EDU83574.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPIFLNFTAGSILPENELASLRYIVQQNQNDTVIIKERYKMDIRYIESVNGFTVNPVCSNHFSIFMARQNTIARNLEQQI
NNGRSFAQISQDFMLQLSSNIGWKKGAENALKNKIHSHSFVVNPDEFSCDTQFLKCPITLCVPEKGVFVKNALNSNICTL
YDKSAFMNLTREHLPHPLSREKIVKEMIIERNMCYFDTISQHFIIMDADQQKQHCK
>SEQF1516_EDU83575.1 IS66 family element, transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQLDKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTL
TGRVYDPAVQRPLRQTRTRKPFPESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
DAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELRRSLLSGWVDACCRLLSPLEEALHGYVMT
DGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNAGSALAPAVWFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELY
RNGGITEAACWAHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWLREKMKT
LSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKNFLFFGSDHGGERGALLYSLIGTCKLNDVDP
ESYLRHVLGVIADWPVNRVSELLPWRIALPAE
>SEQF1516_EDU83576.1 enterobacterial Ail/Lom family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKLYAAILSAAICLAVSGAPAWASEQQATLSAGYLHARTSAPGSDNLNGINVKYRYEFTDTLGLVTSFSYAGDKNRQLT
RYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
GAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF
>SEQF1516_EDU83577.1 tail assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQTESAILAHARRCAPAESCGFVISTPEGEWYIPCVNISAEPEAYFRIAPEDWLRAEMQGEIVALVHSHPGGLPWLSEA
DRRLQIKSALPWWLVCRGDIHKFRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGTDMPDFEREDDWWRNGQNLYLDNMEAT
GFYRISLPSAQPGDILLCCFGASVANHAAIYCGNGELLHHLPEQLSKRERYSEKWQRRTHSAWRHRHWHVSAFTGIYNDL
AAASACM
>SEQF1516_EDU83578.1 phage minor tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEIKTLHLVPREGMQVSEKPSVVRVRFGDGYEQRRPTGLNPQLKTFQAVFRVTDESTRRWLDEFLSWHGGYRAFLWRPP
KHNRTVRVVCREWSVTDNARYSDFSCTIEQVVN
>SEQF1516_EDU83579.1 IS66 family element, orf2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPS
ARDGKVFLTQAQLAMLLEGIDWRQPKRLLTSLTML
>SEQF1516_EDU83580.1 phage minor tail protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNIHEESLNESVKSEQSPRVVLWEIDLTVQGGERYFFCNELNEKGEAVTWQGRQYQVYPIDGSGFEMNGKGSSARPSLT
VSNLFGLVTGMAEDLQSLVGATVVRRRVYARFLDAVNFVAGNPEADPEQELRDRWVVEQMSELTAMTASFVLATPTETDG
ALFPGRIMLANTCMWTYRSDECGYTGGAVADEFDNPTTDIRKDRCSKCMRGCEMRSMVANFGGFLSINKLSQ
>SEQF1516_EDU83581.1 DNA-damage-inducible protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKGSVPALQQEMLRRVSKRYDDVEVIIKSTSNDGLSVTRTADKDSAKTFVQETLKDTWESADEWFVR
>SEQF1516_EDU83582.1 TnpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDEKQLQALANELAKNLKTPEDLSQFDRLLKKISVEAALNAEMSHHLGYDKNQPKPGANSRNGYSTKTVITGDGHLELRT
PRDRDGSFEPQLVKKNQTRITGMDNQILSLYAKGLTTREIAAAFKELYDADVVSVQRGPY
>SEQF1516_EDU83583.1 exodeoxyribonuclease 8 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTDKEEFALYCEAKNDKVRKRLGIKGGFYWTTAKKLSVAISRCITAMDDNDYDEDDFKKPVRVHLPVVNDLPPEGVFDT
EFCNRYEKGGEDGITMVFIAPSPSVQEKPASTDNTNVNGEDMTEIEENMLLPVSGQELPIRWLAQHGSEKPVTHVAREEL
QALHIARAEELPAVTALAISHKTKLLDPLEIRDLHKLVRDTDKVFPNPGNSDLGLITAFFEAYLDADYTDRGLLTKEWMK
GNRVSRITRTASGANAGGGNKTDRNPNLVHTFDTLDVEIAAATLPMDFNIYEIPGSVYRRAKEIVLKRESPFKEWSAALR
ATPGILDYSRAAIFALIRSAHPEFYHYPGRLQGYINAYLTETDHENPSKETLTAARHTPEKDILEEVNRELSAKQETEEE
NDEEKPQPSCAMAE
>SEQF1516_EDU83584.1 transposase, Mutator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNSSDSDQTVQAVRLPDVSPALVSKVTDAVMEQVVEWQNRPLDAVYPIVYLDCIVLKVRQDSRVINKSVFLALGINIEG
QKELLGMWLAENEGAKFWLNVLTELKNRGLNDILIACVDGLKGFPDAINTVYPEARIQLCIVHMVRNSLRFVSWKDYKAV
TRDLKAIYQAPTEEAGQQALEAFASAWDSRYPQISRSWQANWTNLAMFFAYPADIRKVIYTTNAIESLNSVIRHAIKKRK
VFPTDDSVKKVVWLAIQAASQKWTMPLRDWRMAMSRFIIEFGDRLDGHF
>SEQF1516_EDU83585.1 bacteriophage lambda tail assembly protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTAAEAIRALSLQVPGFRRQMNEGWYQIRIAGYDTAPEAVYARLHEQLGEGTVIHIVPRLAGAGKGGLQIVLGAAAIVG
SFFTAGASMALWGSALAAGGFSATTMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGRQNTYFSSLDNMIAQGNPMPVP
YGEMLVGSRRISQDISTRDEGGGGTVVVVGRQG
>SEQF1516_EDU83586.1 site-specific recombinase, phage integrase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNGRMIIRRNLAKDRFTVPKTQAGTNRVIHLIKPAIDALRSQMALTRLSKEHIIDVHLREFGRTEKQKCTFVFQPEVSA
KVKNYGDHFTVDSIRQMWDAAVKRAGIRHRKSYQSRHTYACWSLTAGANPAFIANQMGHADAQMVFQVYGKWMSENNNAQ
VTLLNTQLSEFAPTMPHNEAMKS
>SEQF1516_EDU83587.1 putative prophage tail fibre C-terminus family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNILKKIMQRLCGCGKHDDRENGELLTAQLRLGPADILESDENGIIPEQDRVITQVVILDADKKQIQCVVRPLQILRADG
TWENIGGMK
>SEQF1516_EDU83588.1 IS66 family element, orf1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLDAAAEQPESLAEDPETLSISCEVTFRHGTLRFNGNVSEKLLTLLIQELKR
>SEQF1516_EDU83589.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPGLVSYISSTSFANEMAEMRQQVMEGQIGGFLLGGERVRVSYLFQLH
>SEQF1516_EDU83590.1 putative acyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQKELWINQIKGLCICLVVIYHSVITFYPHMTTFQHPLSEVLSKCWIYFNLYLAPFRMPVFFFISGYLIRRYIDSVPWG
NCLDKRIWNIFWVLALWGVVQWLALSALNQWLAPERDLSNASNAAYADSTGEFLHGMITASTSLWYLYALIVYFVVCKIF
SRLALPLFALFVLLSVAVNFVPTPWWGMNSVIRNLPYYSLGAWFGATIMTCVKEVPLRRHLLMASLLAALAVGAWLFTIS
LLLSLVSIVVIMKLFYQYEQRFGMRSTSLLNVIGSNTIAIYTTHRILVEIFSLTLLAQMNAARWSPQVELTLLLVYPFVS
LFICTVAGLLVRKLSQRAFSDLLFSPPSLPVAVSYSR
>SEQF1516_EDU83591.1 lipoprotein releasing system, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAA
KAELRNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLKAVGLEHRANHRPSELSGGERQRVAIARAL
VNNPWLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEMRDGRLTAELSLMGAE
>SEQF1516_EDU83592.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNVKTLIAAAILSSMSFASFAAVEVQSTPEGQQKVGTISANAGTNLGSLEEQLAQKADEMGAKSFRITSVTGPNTLHGT
AVIYK
>SEQF1516_EDU83593.1 purine nucleoside phosphoramidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIPNILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAE
DGYRLIMNTNRHGGQEVYHIHMHLLGGRPLGPMLAHKGL
>SEQF1516_EDU83594.1 surface antigen domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKSMLAGIGIGVAAALGVAAVASLNVFERGPQYAQVVSATPIKETVKTPRQECRNVTVTHRRPVQDEHRITGSVLGAVA
GGVIGHQFGGGRGKDVATVVGALGGGYAGNQIQGSLQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDRD
PGTQIPLDSNGQLILNNKV
>SEQF1516_EDU83595.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLALLLLVGCRSHPEIPVNDEQSLVMESSLLAAGISAEKPVLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEM
HPLERPRSVTIPAHSAVTLYGSANFLGAHKVRLYLYL
>SEQF1516_EDU83596.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKMSRYALITALAMFLAGCVGQREPAPVEEVKPAPEQPAEPQQPVPTVPSVPTIPQQPGPIEHEDQTAPPAPHIRHYDW
NGAMQPMVSKMLGADGVTAGSVLLVDSVNNRTNGSLNAAEATETLRNALANNGKFTLVSAQQLSMAKQQLGLSPQDSLGT
RSKAIGIARNVGAHYVLYSSASGNVNAPTLQMQLMLVQTGEIIWSGKGAVSQQ
>SEQF1516_EDU83597.1 NADH dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHSHLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQ
LGSVIDIDRDAKTITIAELRDEKGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLK
YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGERILPALPPRISAAAHNELTKLG
VRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGIKAPDFLKDIGGLETNRINQLVVELTLQTTRDPDIYAIGDCASCP
RPEGGFVPPRAQAAHQMATCAMNNILAQMNGKLLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRIARFVYISL
YRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH
>SEQF1516_EDU83598.1 thiamine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPFRSNNPITRDELLSRFFPQFHPVTTFNSGLSGGSFLIEHQGQRFVVRQPHDPDAPQSAFLRQYRALSQLPACIAPKPH
LYLRDWMVVDYLPGEVKTYLPDTNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRP
LRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTEQHRQLVNDYATRAKIYPAQLWRQVRRWFPWLL
MLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ
>SEQF1516_EDU83599.1 transcription-repair coupling factor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPEQYRYTLPVKAGEQRLLGELTGAACATLVAEIAERHAGPVVLIAPDMQNALRLHDEISQFTDQMVMNLADWETLPYDS
FSPHQDIISSRLSTLYQLPTMQRGVLIVPVNTLMQRVCPHSFLHGHALVMEKGQRLSRDALRTQLDSAGYRHVDQVMEHG
EYATRGALLDLFPMGSELPYRLDFFDDEIDSLRVFDVDSQRTLEEVEAINLLPAHEFPTDKAAIELFRSQWRDTFEVKRD
PEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYFPANTLLVNTGDLENSAERFQADTLARFENRGVDPMRPLLPPQSL
WLRVDELFSELKNWPRVQLKTEHLPTKAANANLGFQKLPDLAVQAQQKAPLDALRKFLESFDGPVVFSVESEGRREALGE
LLARIKIAPQRIMRLDEASDRGRYLMIGAAEHGFVDTVRNLALICESDLLGERVARRRQDSRRTINPDTLIRNLAELHIG
QPVVHLEHGVGRYAGMTTLEAGGITGEYLMLTYANDAKLYVPVSSLHLISRYAGGAEENAPLHKLGGDAWSRARQKAAEK
VRDVAAELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDRLVCGDVGFGKTEVAMR
AAFLAVDNHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEMLSRFRSAKEQTQILAEVAEGKIDILIGTHKLLQSDVKF
KDLGLLIVDEEHRFGVRHKERIKAMRANVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSLVVRE
AILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMNDFHHQRFNVLVCTTIIETGIDIPTA
NTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWLLTPHPKAMTTDAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLG
EEQSGSMETIGFSLYMELLENAVDALKAGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRIASAKTENELE
EIKVELIDRFGLLPDPARTLLDIARLRQQAQKLGIRKLEGNEKGGVIEFAEKNHVNPAWLIGLLQKQPQHYRLDGPTRLK
FIQDLSERKTRIEWVRQFMRELEENAIA
>SEQF1516_EDU83600.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQHLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFL
CDIRQVIFNPNLFPYENMEGKIDRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQT
HKFKNISPHLQRIKAFKTLG
>SEQF1516_EDU83601.1 transcriptional regulator, TetR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLADLVEATGAKAPTLYAEFTNKEGLFRAVLDRYIDRFAA
KHEAQLFCEEKSVESALADYFAAIANCFTGKDTPAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGE
IPTHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIAGTTLRLWPELVK
>SEQF1516_EDU83602.1 TonB-dependent siderophore receptor FhuE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSTQFNRDNQYQAITKPSLLAGCIALALLPSAAFAAPATEETVIVEGSATAPDDGENDYSVTSTSAGTKMQMTQRDIPQ
SVTIVSQQRMEDQQLQTLGEVMENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDGKIRARIVGGYQNNDSWLDRYNS
EKTFFSGIVDADLGDLTTLSAGYEYQRIDVNSPTWGGLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQRFAD
TWQATLNATHSEVEFDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYELFGRQHNLM
FGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDWSPQSLAQDDTTHMKSLYAATRVTLADPLHLILGARYTNWRV
DTLTYSMEKNHTTPYAGLVFDINDNWSTYASYTSIFQPQNDRDSSGKYLAPITGNNYELGLKSDWMNSRLTTTLAIFRIE
QDNVAQSTGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVNPNLPRTTVKMFTSYRL
PVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLFTRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGAPRN
FSITGTYQF
>SEQF1516_EDU83603.1 lipoprotein-releasing system transmembrane protein LolC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTVLSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQL
PETAVKLDGVNRVAPITTGDVVLQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGD
QIRVMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGYEMLVNIEDASRLMRYPAGNITGWRLWLDEPLKVDSLSQQKL
PEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVAVAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGAS
AGIIGAILGAALGALLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQPAEALRYE
>SEQF1516_EDU83604.1 LysM domain/ErfK/YbiS/YcfS/YnhG family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKTRFSRWLTFFTFAAAVALALPAKANTWPLPPAGSRLVGENKFHVVENDGGSLEAIAKKYNVGFLALLQANPGVDPYV
PRAGSVLTIPLQTLLPDAPREGIVINIAELRLYYYPPGKNSVTVYPIGIGQLGGDTLTPTMVTTVSDKRANPTWTPTANI
RARYKAQGIELPAVVPAGPDNPMGHHAIRLAAYGGVYLLHGTNADFGIGMRVSSGCIRLRDDDIKTLFSQVTPGTKVNII
NTPIKVSAEPNGARLVEVHQPLSEKIDDDPQLLPITLNSAMQSFKDAAQTDAEVMQHVMDVRSGMPVDVRRHQVSPQTL
>SEQF1516_EDU83605.1 beta-N-acetylhexosaminidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRELVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPA
AQSFAALLGMEEGGKLAQEAGWLMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPEKALAIASRFIDGMHEAGMKT
TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSTLIRENKLDAIMPAHVIYSDVDPRPASGSSYWLKTVLRQELG
FDGVIFSDDLSMEGAAIMGSYAERGQVSLDAGCDMILVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARW
KAISARLNQLHERWQEEKAGH
>SEQF1516_EDU83606.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPYISPLFPFLPANALKRHSLFGLHDKYECVYFSFAFAFAFAFASKIIRTLNITAHHPPPA
>SEQF1516_EDU83607.1 putative transcriptional regulator EnvR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVTRGAIYWHFENKTQLFNEMWLQQPSLRELIQEHLTAG
LEHDPFQQLREKLIVGLQYIAKIPRQQALLKILYHKCEFNDEMLAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLD
VVMIIIDGAFSGIVQNWLMNMAGYDLYKQAPALVDNVLRMFMPDENITKLIHQTNELSVM
>SEQF1516_EDU83608.1 DNA methylase, N4/N6-methyltransferase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTGCEPTRFGNEAKTIIHGDALAELKKLPTESVDLIFADPPYNIGKNFDGLIEAWKEDLFIDWLLEVIAECHRVLKKQG
SMYIMNSTENMPFIDLQCRKLFTIKSRIVWSYDSSGVQAKKHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALI
DYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIVLDPFAGSFTTGAVAIASGRKFI
GIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTGNLSKRSRLSEVDPDLITK
>SEQF1516_EDU83609.1 amino acid ABC transporter, periplasmic amino acid-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKMMIATLAAASVLLAVANQAHAGATLDAVQKKGFVQCGISDGLPGFSYADADGKFSGIDVDVCRGVAAAVFGDDTKVK
YTPLTAKERFTALQSGEVDLLSRNTTWTSSRDAGMGMAFTGVTYYDGIGFLTHDKAGLKSAKELDGATVCIQAGTDTELN
VADYFKANNMKYTPVTFDRSDESAKALESGRCDTLASDQSQLYALRIKLSNPAEWIVLPEVISKEPLGPVVRRGDDEWFS
IVRWTLFAMLNAEEMGINSQNVDEKAANPATPDMAHLLGKEGDYGKDLKLDNKWAYNIIKQVGNYSEIFERNVGSESPLK
IKRGQNNLWNNGGIQYAPPVR
>SEQF1516_EDU83610.1 acriflavine resistance protein E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIVKTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLNRNF
TEGSDVQAGQSLYQIDPATYQANYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAK
ATVESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQSSNDFMRLKQSVEQGNLHKENAT
SNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLRAVFPNPQHTLLPGMFVRARIDEGVQPDAILIPQQGVSRTPRGDA
TVLIVNDKSQVEVRPVVASQAIGDKWLISEGLKSGDQVIVSGLQKARPGEQVKATTDTPADTASK
>SEQF1516_EDU83611.1 hypothetical protein ECH7EC4501_5661 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVSVSIFLVGSAKVKLMRYFESSEITRYNMLNQQRISQQNIAIFYLM
>SEQF1516_EDU83612.1 DNA-binding protein Fis [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALM
MGINRGTLRKKLKKYGMN
>SEQF1516_EDU83613.1 amino acid ABC transporter, permease protein, His/Glu/Gln/Arg/opine family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKVLLSHPSRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWLMWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFI
HERFGQFMYGLYPHDQRWRINLALLIGLVSIAPMFWKILPHRGRYIAVWVVIYPLIVWWLMYGGFFALERVETRQWGGLT
LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVMLPLFMAEGTSIDKLIRALVGVIL
FQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQGLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQ
ATVDPAWLGMSTEGYVFAALIYWIFCFSMSRYSQHLEKRFNTGRTPH
>SEQF1516_EDU83614.1 ribosomal protein L11 methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPLPGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLG
AGFAHKIEQLEDKDWEREWMDNFHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGK
TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQPEEMKADVVVANILAGPLRELA
PLISVLPVSGGLLGLSGILASQAESVCEAYADSFALDPVVEKEEWCRITGRKN
>SEQF1516_EDU83615.1 amino acid ABC transporter, permease protein, His/Glu/Gln/Arg/opine family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTVTNLNNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTY
GRVFIVGLLNTLLVSALCIVFASVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWPIAAVLIIGLPLLAQWLFGAALH
WDVPALQGFNFRGGMVLIPELAALTLALSVYTSAFIAEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIP
PLTSQYLNIVKNSSLAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVER
>SEQF1516_EDU83616.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQWIELLATETDKCRNMNSVNPLKLVNCDELNFQDRM
>SEQF1516_EDU83617.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRLIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTTQDNWETAGAIAGGAAAVAGLTMGIIALSK
>SEQF1516_EDU83618.1 tRNA-dihydrouridine synthase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSSNPQVWESDKSRLRMVHIDEPGIRTVQIAGSDPKEMA
DAARINVESGAQIIDINMGCPAKKVNRKLAGSALLQYPDVVKSILTEVVNAVDVPVTLKIRTGWAPEHRNCEEIAQLAED
CGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPVIANGDITDPLKARAVLDYTGADALMIGRAAQGRPWIFREIQHY
LDTGELLPPLPLAEVKRLLCAHVRELHDFYGPAKGYRIARKHVSWYLQEHAPNDQFRRTFNAIEDASEQLEALEAYFENF
A
>SEQF1516_EDU83619.1 amino acid ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQILLQPANAMITLENVNKWYGQFHVLKNINLTVQPGERIVLCGPSGSGKSTTIRCINHLEEHQQGRIVVDGIELNEDI
RNIERVRQEVGMVFQHFNLFPHLTVLQNCTLAPIWVRKMPKKEAEALAMHYLERVRIAEHAHKFPGQISGGQQQRVAIAR
SLCMKPKIMLFDEPTSALDPEMVKEVLDTMIGLAQSGMTMLCVTHEMGFARTVADRVIFMDRGEIVEQAAPDEFFAHPKS
ERTRAFLSQVIH
>SEQF1516_EDU83620.1 N-acetylmuramoyl-L-alanine amidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLEQGWLVGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFGGPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRR
DGEIVQYVPFDKRAWHAGVSQYQGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDCYPDIANNMTGHCDIAPD
RKTDPGPAFDWARFRALVSKETT
>SEQF1516_EDU83621.1 dihydrolipoamide dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNGRHKKNVRPAGDKYIEVMMSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHV
AKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFD
NAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIV
KVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGFIRVDK
QLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEVIAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATF
PWAASGRAIASDCADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHESVGLAAEVF
EGSITDLPNPKAKKK
>SEQF1516_EDU83622.1 type 4 pilus subunit PilA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQTFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTR
YVSAMSVAKGVVSLTGQESLNGLSVVMTPGWDNANGVTGWARNCNIQSDSALQQACEDVFRFDDAN
>SEQF1516_EDU83623.1 pyruvate dehydrogenase (acetyl-transferring), homodimeric type [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEARKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELER
RIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDEPESK
GAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVD
GDYQTFKSKDGAYVREHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTIKGYGMGDA
AEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHTYLHAQRQKLHGYLPSRQPNFTEKLELPSLQ
DFGALLEEQSKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKED
EKGQILQEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQ
HEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETI
EGSKGKVQLLGSGSILRHVREAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPAVA
STDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGELAKRGEIDKKVVADAIAKFNIDAD
KVNPRLA
>SEQF1516_EDU83624.1 type IV pilus assembly protein PilC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASKQLWRWHGITGDGNAQDGMLWAESRTLLLMALQQQMVTPLSLKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEG
LALLAEQHPSKQWQALLQSLAHDLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQRAQRQLTDKVK
SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLADFSGEWGWLLVLFGIMLTIANKLLMRRPTW
LIARQKLLLRIPIMGSLMRGQKLTQIFTILALTQSAGITFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNA
GEFSPLCLQLVRTGEASGSLDLMLDNIAHHHRDNTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHLGDAMSGMG
>SEQF1516_EDU83625.1 dihydrolipoyllysine-residue acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGA
ADAAPAQAEEKKEAAPAAVPEAAAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
KVNTGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAAPAPAAGVKEVNVPDIGGDEVEVTEVMVKVGDKVAAEQSLIT
VEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMIFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEF
AENDAYVHATPLIRRLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKVDFSKFGEI
EEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAKRKLDVKITPVVFIMKAVAAALEQMPRFNSS
LSEDGQRLTLKKYINIGVAVDTPNGLVVPVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTH
FAPIVNAPEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSDIRRLVM
>SEQF1516_EDU83626.1 hypothetical protein ECH7EC4501_4761 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGNVLTWVIPYLSNNVEFSGTCPIELSPESSIRQVLRLVAALLYALDLQHLLDNFYQKNH
>SEQF1516_EDU83627.1 dephospho-CoA kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGAPALHAIADHFGANMIAADGTLQRRALRERIFANPEE
KNWLNALLHPLIQQETQHQIQQATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP
>SEQF1516_EDU83628.1 aromatic amino acid transport protein AroP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSAGPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSH
FAYKYWGSFAGFASGWNYWVLYVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVTVFGEMEFWFAIIKV
IAVVAMIIFGGWLLFSGNGGPQASVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLELVGITAAEADNPEQSIPKATNQV
IYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIFHELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAP
KALASVDKRGVPVNTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQGVVTRFPALL
YPLGNWICLLFMAVVLVIMLMTPGMAISVYLIPVWLVVLGIGYLFKEKTAKAVKAH
>SEQF1516_EDU83629.1 guanosine monophosphate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSWSGVPIIAANMDTVGTFSMASALASFDILTAVHKHYS
VEEWQAFINNSSADVLKHVMVSTGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIISDGGCTTPGDVAKAFGGGADFVM
LGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMKRHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVG
ASRLKELTKRTTFIRVQEQENRIFNNL
>SEQF1516_EDU83630.1 GspE family protein HofB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIPQLTALCLRYQGVLLDASEEVVHVAVVDAPSHELLDALHFATTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQP
KAELLTRTLQSALEQRASDIHIEPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVEL
AGNAVSFRIATLPCRGGEKVVLRLLQQVSQALDVNTLGMQPLQLAGFAHALQQPQGLVLVTGPTGSGKTVTLYSALQKLN
TADINICSVEDPVEIPIAGLNQTQIHPRAGLTFQGVLRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNS
TCETLVRLQQMGVARWMLSSALTLVIAQRLVRKLCPHCRRQQGEPIHIPVNVWPSPLPHWQAPGCVHCYHGFYGRTALFE
VLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEELIRVLGMPHGE
>SEQF1516_EDU83631.1 protein AmpE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTLGMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLL
CIGAGKVRLHYHAYLTAASRNDSHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKALPAWFASLGDFRTSQYQVLTRLA
QFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIALLTIYGALV
>SEQF1516_EDU83632.1 transcriptional regulator, GntR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQFDVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQ
SFSDPLVELLSDHPESQYDLLETRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAREASHRHLAFIEEILLDRSREES
RRERSLRRLEQRKN
>SEQF1516_EDU83633.1 nicotinate-nucleotide diphosphorylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANNDITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQ
LAGDDVTIIWHVDDGDVINANQPLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVENLEELDEALKAGADIIMLDNFET
EQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVDFISVGALTKHVQALDLSMRFR
>SEQF1516_EDU83634.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLIKAFQKIHVEPPLVLSIGNHRLYPEEGSAPDEVAMRDYAKVSPRFWLGETGRELRKAGAEAQVVAFYLMTSPHANML
GLYYLPVLYLAHETGLGLEGASKGLKRAVEAGFCSYDHDAEMVWVHEMAAWQVGETLKPGDNRCAGVRNEYASLPENAFL
SVFYDRYKTDFHLDVRRNNSRNSVRGFEGAFKGLRSQEQEQEQEKEQEQDKNTMVHGKKNTTNQAGDVQTVNPGQPAGTT
PEADSGAVQQVMTAGSEQSHQLQQPEADSAIQREADRVVPESTGQSVGRVDYPDVFEQVWREYPLRAGANPKKSAFSAWK
ARLREGVPPETMLDGVRRYARYLAATGKAGTEFVQRATTFFGPDRNFENPWLLPVSGTNNQRCVNHISEPDTEIPPGFRG
>SEQF1516_EDU83635.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARQETLWLCINWVINMSNDKKLTLSVYENSPHIWRGGLSDVELAEWLIHKANALLWRLSAREQRKETRIKLADAEACAG
LIEDYTNLGISSAESDPIQPLSRESIQHAGCMAHLVTARQHEVGIGSLPAGYSLIPELVEARKSVQKKRDDALQLLREHY
GAIPECEQRRYPEGYEWMQSLFEVR
>SEQF1516_EDU83636.1 acylphosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKVCIIAWVYGRVQGVGFRYTTQYEAKRLGLTGYAKNLDDGSVEVVACGEEGQVEKLMQWLKSGGPRSARVERVLSEPH
HPSGELTDFRIR
>SEQF1516_EDU83637.1 sulfurtransferase tusE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGISLSPEHWEVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGN
SRYLYRLFPKGPAKQATKIAGLPKPVKCI
>SEQF1516_EDU83638.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGTALSPIVSEFETTEQENSYNEWLRTKVTSSLADTRPAIPHDEVMAEMENLIAQIAVTNKSE
>SEQF1516_EDU83639.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METVSDALKALKKASSHVVAARLGISREEAVNELWELKINGVVDKTGHTWFLAGEGESRVTEERPVKSEAQDMLTGEVEQ
KVTADMMIEFIGQDGAKTCEELAGKFGVSTRKVASTLAVVTATGRLARVNQNGKFRYCMPGDNLPAEPKAALVTESDGKA
FPQPAGAALPVREAATQEEIKTETVADIVQPLPSFTETQADELIFPSLRRANLALRRAKSDVQKWERVCAALRELNKHRD
IVRQITDSSRRVVSEK
>SEQF1516_EDU83640.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDSTREKIRQKYTQAEIGRYMGVAQQTVWQWFSFGVPPKQVIPLCQLMKWEVTPHEIRPDIYPNPTDGLPVGCKVNTSN
APELIHENQA
>SEQF1516_EDU83641.1 hypothetical protein ECH7EC4501_5735 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHLVARTTEPGLSDNVSFSRKILIGEQTMITEQTTTIIILLSLAIG
>SEQF1516_EDU83642.1 hemimethylated DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVNDELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDE
HPEQPSMDELAQTIRKQLQAPRLRN
>SEQF1516_EDU83643.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFDTIMEKAYEEYFEGLAEGEEALSFSEFKQALSSSAKSND
>SEQF1516_EDU83644.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFKDLLKEIQEIAAHALHQRLNEVELESATKKYIDNMARNVRDAFTGLYSVSVTNNQNTEETAKRIASVMGFHVEEKYS
KKEFWKTTKKLQSENCHLLRQSLLSMRKVIQMTQDYRNCSHYLKNSELS
>SEQF1516_EDU83645.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKLVEVSGHPLHWFLLPPEECEQIFTPDTMKIGPRQRELLQAFSAFPEEDQEKMLQEIKDKKKSMEETIARWLAAQKSR
RA
>SEQF1516_EDU83646.1 exonuclease family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKIFICAAIPDEQAIKEDSAVAVATAIEAGDERRARAKFHWQFLEQFPAAQDCAYKFIVCEDKPGIPRPALDSWDTEYM
QENRWDEESASFVPVEPESDPMNVNFDKLSPEVQNAVLVKFDTCENITVDMVISAQELLQEDMATFGGHIVEALMKMPEV
NAMYPELKLHAIGWVKHKCEPGAKWPEIQAEMRIWKKRREGERKETGKYTSVVDLTRARVNQQNTENAAEKTGAVTVAIR
REYKQTWKTLDNELACALWPGDVDAGNIDGTIHRWATNEVIDKDREDWKRISASMRKQPEALGYDRQTIFGLVRERPIDI
HKDPVALNKYISEYLTTKGVFEHEETDQSSTDALQPSAAQTAPVETAESDTQKNEILVEAEPSVEREGPFYFVFTDKGGE
KYGRANKLSGLDKALAAGGTEISKEEYFARKNGTYTGLPQNVDTAEDSEQSEPVKVTADEVNKIMQAANISQPDADKLLA
ASRGEFVEGISDPNDPKWVKGIQSRDAEDQNQPNVKQNEPEAEQNSPDTQQNGPEEQQPEPAVQQELEKVCTACGQTGGG
NCPDCGAVMGNATYLETFDEENQAEAQKNDPEEMEGTEHLHKENTGSDQYHASDNKTGETANPLIKVNGHHEISSTSRLW
HHLMIDLETMGKNPDAPINSIAGKFFDPATGEMGPEFSKTIDLETAGGVIDRDTIKWWLKQSREAQSSILTDEITLDDAL
LQFREFIDENSGEFFVQVWGNGATFDNVILRRSYERQGIPCPWRYTNDRDVRTMVALGLVMDFDARTTIPFEGERHNALH
DARYQAKYVSAIWQKLLPSQADF
>SEQF1516_EDU83647.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKVFTQEEREKIKGQVVELVRRSGRETLRQLEAKTGATRYLMSVLARELVASGDVYNSGYGLFPSEQARKDWQNARKKL
SRAKLKKPVVVDPDLIWSLPDGEIRRYDRQLNIICSECRNSEVMQRVLIFYTGVMME
>SEQF1516_EDU83648.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTTFALVLTVYLVSGESLELVTGLYGSMKECMAAAAEQKIPGNCYPVDKTTHTNNNEIPAGL
>SEQF1516_EDU83649.1 phage antitermination Q type 1 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARDIQMVLERWGAWAANNHEDVTWPSIAAGFKGLIPTKVKSRPKCSDDDAMIICGCMARLNKNNQYLHDLLVDYYVGGM
TFMALARKHRCSDGLIGKRLYKAEGIIEGMLMALNVRLDMDMR
>SEQF1516_EDU83650.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKHEHIRMAMNAWAHPDGEKVPAAKITKAYFELGMTFPELYDDSHPEAMARNTQKIFRWVEKDTPDAVKKIQALLPAI
EKAMPPPLVARMRSHSSAYFRELVETKERLVKDIDDFVASAIVLFDQMNRGGPAGNTLAVH
>SEQF1516_EDU83651.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVLLRPVLVPELGLVIVKPGRESMSAFHNGRILVEPEPKSMRALPSGVVPAVHQPLAEDKSLLPFFSDERVIRAAGGAG
ALSDWLLRHVKSCQWPHGDYHHSETVIHRYGTGAMVLCWHCDNQLRDQTSESLEQLAQQNLAAWMIDVIRHAMNGIQERE
LSLAELSWWAVCNQVVDALPEAVSRRSLGLPAEKIRSVYRESDIIPGEQTATSILKQRTKNIALPPHTHQQQNPPQEKTV
VSIAVDPESPKSFMKRPKRRRWVNEKYTRWVKTQPCACCGKPADDPHHLIGHGQGGMGTKSHDIFTLPLCREHHNELHAD
PLAFEEKHGSQVDLIFRFLDHAFATGVLG
>SEQF1516_EDU83652.1 DNA replication protein dnaC homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIAAAGVLERIRRLAPQASVPPYRTVEEWREWQLAEGRKRSEEINRQNHQLRVEKILNRSGIQPLHSKCSFANYQVQN
DGQKYALSQAKSIADELMTGCTNFVFSGKTGTGKNHLAAAMGNRLMAKGRSVIIVTVSDVMSVLHDSYDNGKSGEKFLQE
LCSVDLLVLDEIGVQRETKNEQVVLHQIIDRRTASLCSVGMLTNLNHAAMSTLLGERIMDRMTMNGGRWVTFNWDSWRPN
VSNMRVVK
>SEQF1516_EDU83653.1 DicB protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKLSCNASTSELRFEIGVITGDKTFIEDAIKQRKLEQDLLNEVCIPSMLARLDLLQKGYKQ
>SEQF1516_EDU83654.1 crossover junction endodeoxyribonuclease RusA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIEFVLPYPPTVNTYWRRRGSTYFVSKAGERYRRAVALIVRQQRLKLSLSGRLAIKIIAEPPDKRRRDLDNILKAPLDA
LTHAEVLIDDEQFDEINIVRGQPVPGGRLGVKIYEIRGGNDGA
>SEQF1516_EDU83655.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDRIVSSSHDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTVLMLPSPGLILTLVGMYGLMFLTYKMANKPTGIISAF
AFTGFLGYILGPILNTYLSAGMGDVIAMALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPAL
HLAISAVFILISSGAILFETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASRD
>SEQF1516_EDU83656.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKHMDIHCQTRIFNSINHDTKYKICIFTPKNIKKNNATLYILDGNSANNYISDILPVIDALPNPPVLVTLGYESWNNLS
IHRRAYDYTPDGENAIVDNSKPAWIYFTGGGSQSFRELLLTQIMPWVSTIAPNSSRIGIWGHSLGAIFVLDCLKNNSCFN
YYYISAPSLLWQNERIIKIIKDDISESKHTKSICLLNGNLSLDYSASLYPEAIKAESVLRNILTEKYSNFSIVQFPELNH
QETFSAALWNSIIHFSI
>SEQF1516_EDU83657.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKASLGETIDIVDHQGKWLARGAYSPASQIRARVWTFDPSESIDIAFFS
RRLQQAQKWRDWLAQKDGLDSYRLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECAIYDRSDVA
VRKKEGMELTQGLVTGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRYVENKRVLNCFSYTGGFAVSALM
GGCSQVVSVDTSQEALDIARQNVELNKLDLSKAEFVRDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKD
INMLAIQLLNEGGILLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFACRVM
>SEQF1516_EDU83658.1 site-specific recombinase, phage integrase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGRPRKNKKDNVLPPRVRSNGYSYVWKPEGSTRSIGLGRVRKTSVAKVWQNYELEKAKLHNIMTVAKLWHMFMDSPAFTE
LAPRTQKDYRQHQKALLMVFGKVLADNVKTEQVRIFMDKRGLESKTQANHELASLSRVYGWGYERGYVKNNPCKGVRKFS
LKARTVYITDEQYAAIYAEAIPQLRIAMEISYLCAARLGDVLELKWQDIMDKGIYIEQNKTGTKQIKEWSPRLRTAIQLA
RNVSSCTCEYVINTTKGGKVIAKTLNNWWNQAKRAAEQKVGVPFGCNFHDIKAKGISDYEGSSRDKQIFSGHKTENQVLI
YDRKTKITPTLDLPLVVSK
>SEQF1516_EDU83659.1 CAAX amino terminal protease family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWIVLVLSLSTLSWHKVVAFSLLTVSVVLAVLNDIIDWSVLFFVATIVFFIILKFNWKYNAWAKSIYEVGIVLSAIALFF
HLWPGFHNPVVLNSVTVGPQSTPYTMYFNFDKALVPFLLVLCTSSLFKKEVKSEVSLWKWGALSLSVPLILFLAVFFGGL
KPEIHFPEWLPEFILANLFFVSLAEESLFRGYIQSRLSEVTSPLVALIVAALLFGFYHYSGGALLVLFATLSGVVYGLSW
MWSGRLWVATLFHFGLNLCHLLFFTYPFLKHN
>SEQF1516_EDU83660.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPNKPCPACNALSGFLEKGGYYIFNCPEHVEFHISKLDSIITKPNQYQSDLLNKELNAARD
>SEQF1516_EDU83661.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRGANIWFASRRIVGVSALLTSASHPVGGLLLNNQPLREFRICHTP
>SEQF1516_EDU83662.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTVTSAQANKLYQVALFTAANRNRSMVNILTEQQEAPKAVSPDKKSTKQTSAGAPVVRITDLNKQAGDEVTFSIMHKLS
KRPTMGDERVEGRGEDLSHADFSLKINQGRHLVDAGGRMSQQRTKFNLASSARTLLGTYFNDLQDQCAIVHLAGARGDFV
ADDTILPTAEHPEFKKIMINDVLPPTHDRHFFGGDATSFEQIEAADIFSIGLVDNLSLFIDEMAHPLQPVRLSGDELHGE
DPYYVLYVTPRQWNDWYTSTSGKDWNQMMVRAVNRAKGFNHPLFKGECAMWRNILVRKYAGMPIRFYQGSKVLVSENNLT
ATTKEVAAATNIDRAMLLGAQALANAYGQKAGGHFNMVEKKTDMDNRTEIAISWINGLKKIRFPEKSGKMQDHGVIAVDT
AVKL
>SEQF1516_EDU83663.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISDKLITLVKSLCVLVGISFLVMLVAIFFSTAWRVLTLSGLVG
>SEQF1516_EDU83664.1 hypothetical protein ECH7EC4501_5535 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRSDASRCYSGNDNAVKKGEQYAPPNRKKIAIINEVI
>SEQF1516_EDU83665.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFEFTGEETPEQLEKMLEGLGDVDIDSHAQDVVTEDTTEKHADEEAQTQTGDNNVAPTPDASVEQTQDVKEPEAKGVLT
RDGKHVIPYEVLEAERSGKQRAEQEAALLRGQIAEEKRRVELLTSQIHQAGMKPTPLPENEKISDEQIARIREMYPEIGD
AVASLIRKNNYLQSRVQQSAQQAEGNGGEDLSPVLDAMNAVPVLKTWQESDPDRFSVAVSIDGKLQNDPAWKDKTLTERF
AEVARRTQVAFGEVSESSADNKADKTDIRKTAEEKVKTAEQEQAVPASPSDLGTTASVGTGDNFERLLGASHSEAEAIMR
GMTNAEIDALLEKLG
>SEQF1516_EDU83666.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEITSLVTAEAVKDVLRSEEVRSALKQKLRHNLEARLDAEVDAILDELLGVQAEPPTEAGDTTAESGEVQPESPVADAT
EPQPESVMML
>SEQF1516_EDU83667.1 putative outer membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEYGFAIYNRNNVNVTGVLTPVFFLDRFTAESGSKTYTNKPDGKSLQAVCCLFPWNNVFADRKVPKITINDNTVTWSNLE
QGMGSYIYTFWG
>SEQF1516_EDU83668.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYGLSIMKPDGSVWISPGFTPQCLINKGTIPATEKSFFKTSIPSGKSCFFFIRTEKKADVMYTHEQIDGYHALRLHVIVR
GTNPGVTTVYAFANMVTPPSEYGIAMYNPDGEMIYHGEMMLLDAKLIPVDIKFEKDLGYPCAIMPALVGYYNWKRTPYDR
PIYTTSTGATGNKIYSCEHYSGGATWDIRKPYIDKVLVINTSVYD
>SEQF1516_EDU83669.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKIAVVYIGPKPVKKDTITGSRTLFPRLEPVHVDSAMAWQLLGFPDVWVRHEELDDVLKKQQQNEQLRQAQQAQERVL
AALAEAENSFVVSVNGQEVDLSKLTSARLATLCEAEELDIHKDPKETAEAFRIRVREAFRRRVAETEQHGGTE
>SEQF1516_EDU83670.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRKPWRAGKDLSTVVENMEIGTGQRGDGRHAFVTREELVGLKLARRRTSGGASYALNPGIEIDSTLMTVDFPTKPLNFK
ATGGFGSVLLEWDMPNYRGHSLTEIWRGTEDDLADAVLVATTPGQVYGDPVDPGWSGFYWIRFVNAAGVKGPWNAEKGTQ
AQTQIGVKAIIDQIRDEAAKSPVVSELRKEIKNAQGQAVKDAAIKTTEVVGTLREETTRTIGGIETRISTLDSSTSESLN
EVDKRITKLDKEGGEAFLAMWSKKAGVDGITAGIGIVAGKDSEGRPVSQVAISASQLFVFDPNNPDNTAYPFAVSGGKVV
IPKAMIYDAVIETLVSRKVVADEVKAGVSITSPVIRSAVIQNGNFQVDSQGNLNIGGLFSVTSQGQLTIRYSNQNVGLVI
RNDKIEVYDQNGRLAVRIGRLR
>SEQF1516_EDU83671.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPYIDITTMRGMMPRVVTSMLPEHSAVLAEDCHFRFGVITPERQISGVEKTFTIKPKTIFHYRDDFWFAWPDVVDVIRSP
IAQDPHGRIYYTDGRFPKVTDATIATKGDGNHPTSSYRLGIPAPTTAPVCTVQQGGDVSDDNPNDDETRFYTETFVSDYG
EEGPPGPASLEVTLRTPGTAVQLTLAPVPLQNASIKRRRIYRSASGGGEADFLLVAELDASVLSYTDKIPAKNLGPSLAT
WDYLPPPENMTGLCLMANGIAAGFAGNEVMFSEAYLPYAWPEVNRHTTAEDIVAICPLGTSLVVATKGEPYLFSGVSPST
ISGSKIPSMQACLSRRSMVAMEGFVLYAGTNGLVSVDANGNVALATEQIVSPEQWQSQFNPASIVAYPWRGEYIACYTKP
DGKQDVFVFSPVNMDIRYLSTPFDCAWVDLAKDMMRVVTGDKMSVLAGGALPSTIRWHSKIFSLPERTSFSCIRVKSPAP
ERVGITIMADDVPVIHFAPGTFKGSVVRLPAATGQNWQVMVSGFGQVERITLSTSMSEMPV
>SEQF1516_EDU83672.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKLDWKKLEQAFRREHAETGITLLDWCRKKKINYNTARTRIKMGKIDHEIDHKTDHEIDHDISDEEPCNDAGSGDEKCA
KNSEKNCANSAETKRIRGSRLLPPSNAFSQRNTHAVRHRGYAKYLEADNLMDDASDMVLFDELVFTRARALSVTKALKGM
FADLEEATDVETRVALYDKILKAEQALDRNIARIESIERSLLTLDVLAETAPKLRADRERINAARDKLRAETDILTNQRR
GVVTPVSDIVSSLHEMSNSGRLDDIPEE
>SEQF1516_EDU83673.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQKSLITVTICMTVIFTIWMLHGSLCEFRLNLWGAEFAAFLQCKQ
>SEQF1516_EDU83674.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGAISREAACPVRWWKKPDKTTALCKYRSNMVLLCEI
>SEQF1516_EDU83675.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQDNQMARYGVNRPDNPDSNTLGLRNALAIAGAKNGIREAEQDRQMNILTGASAPARQKLSVGGQLVAA
>SEQF1516_EDU83676.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAELSDFLPYVRRHISGPLNIMMTDALSMAAVAFSRQSLVCRREVTVVPVAGKEIVLPYDKDDEECVHIIRISDDNHELF
VGRDVDISSGRSLRFACSPGEVSVLYAVAPKAGRSQIPDELLTWPEEVAAGALERLFMQTGVSWSDPLRAQYFSVQFSEG
IRRAYRHTLATSPYSSYRNPVRRQRFF
>SEQF1516_EDU83677.1 IS1203 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU83678.1 outer membrane protein Lom [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSIATLVVCAISGIACVNLSAHAAEGEHTISLGYAHFQFPGLKDFVKDATAHNRETFSHFVNRNYFSSLGEYTDGRVSG
YEGKDKNPQGINIRYRYEITDDFGVITSFTWTRSLTNSQTFIDVQSADHTRKIKNPAASARTDIRANYWSLLAGPSWRVN
QYMSLYAMAGMGVAKVSADLKIKDNINSSGGFSESNSTKKTSLAWAAGAQFNLNESVTLDVAYEGSGSGDWRTSGVTAGI
GLKF
>SEQF1516_EDU83679.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDKILWYMQRVVRNSRNPEFMNEVKDACLKKQAFCFEAPDGFLVLRSVLSADGIPYVLVLLGVCTGSNSVERYLPEVKT
LTHLAGGRWAEFHTARRGFIRLGKRLGFERMPDDEDGFMVFRIAV
>SEQF1516_EDU83680.1 Bor protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKMLLATALALLITGCAQQTFTVQNKQTAVAPKETITHHFFVSGIGQKKTVDAAKICGGTENVVKTETQQTFVNGLLGF
ITLGIYTPLEARVYCSQ
>SEQF1516_EDU83681.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGGSKGGGDTKVKPTAAQIAQEEVAWKGWQDYKNILRPAEDNFMEKVDDLNSEQQYDNIAGTTNLGYQKQFGEARKELAG
NLAQSGVDPSSGRFNAVMNANQSDQVTGQIDTTTRGQVSQADKYVAGLQDVAALGSGQKADALQSFNSLADSSLAKAKSD
AQAAFTKQQGRASLVGAGLGAAGAYAMHKAGGSGGSGGAKTPGTGANAIQHQAQNWRL
>SEQF1516_EDU83682.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQMEKITTGVSYTTSAVGTGYWFLQLLDRVSPSQWAAIGVLGSLLFGLLTYLTNLYFKIKEDRRKAARGE
>SEQF1516_EDU83683.1 large subunit terminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEAEQRLFIMTKLSNPWWRLNHLYKIQNEKGELVTFRMRPAQRQLFRSMHNKNIILKARQLGFSTAIDIYLLDQALFIP
HLKCGIVAQDKQAASEIFRTKIAVPFDHLPDWLRASFTIVERRSGASGGYILFGHGSSIQVATSFRSGTVQRLHISEHGK
ICAKYPAKAKELRTGTLNAVSDECIIFDESTAEGVGGDFYEMSNRAQEITASGLLLTAQDYKFHFYAWWQDPKYSARVPE
SGLKLSREKMTYFSAVEKAMNITLTDEQKQWYINKETEQREEMKQEFPSTPQEAFLTSGRRVFSAESTLQAESFCSPPMI
VYDIEPVTGAKTKAQSLREGNKNELQRTLMNYLLVWELPDPDEEYVCGADTAEGLEHGDRSSLDVVKRSNGEQVAHWFGH
LDAELFAHLISQVCRMYNNAFVGPERNNHGHAVILKLRELYPTRYIYNEQHLDQAYDDDTPRLGWLTTRQSKPVLTEGMK
TLLNNGISGIRWSGTLSEMNTYVYDAKGSMNAQEGCFDDQLMSYMIAQEMRARMPVRVKQKTDKRRTTHWMAH
>SEQF1516_EDU83684.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGYGLLDIANQSRREALQGISDADRRREEIEAANKQMAAQQKAQNKQNIGTGIGTGAAIGASVGGPVGAVAGAVIGGIAG
SLF
>SEQF1516_EDU83685.1 putative phage portal protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNETNTMATKNDNGATPRFSQRQLQALCSDIDSQPKWRDAANKACAYYDGDQLPPEVLQVLKDRGQPMTIHNLIAPTVD
GVLGMEAKTRTDLVVMSDEPDDETEKLAEAINAEFADACRLGNMNKARSDAYAEQIKAGLSWVEVRRNSDPFGPEFKVST
VSRNEVFWDWLSREADLSDCRWLMRRRWMDTDEAKATFPGMAQVIDYAIDDWRGFVDTTVTEGQPSPLMSAWEEYQSWDR
QQNEWLQRERRRVLLQVVYYRTFERLPVIELSNGRVVAFDKNNLMQAVAVASGRVQVKVGRVSRIREAWFVGPHFIVDRP
CSAPQGMFPLVPFWGYRKDKTGEPYGLISRAIPAQDEVNFRRIKLTWLLQAKRVIMDEDATQLSDNDLMEQIERPDGIIK
LNPVRKNQKSVADVFRVEQDFQVASQQFQVMQESEKLIQDTMGVYSAFLGQDSGATSGVAISNLVEQGATTLAEINDNYQ
FACQQVGRLLLAYLLDDLKKRRNHAVVINRDDRQRRQTIVLNAEGDNGELTNDISRLNTHIALAPVQQTPAFKAQLAQRM
SEVIQGLPPQVQAVVLDLWVNLLDVPQKQEFVERIRAALGTPKSPDEMTPEEQEVAAQQQALQQQQAELQMREMAGRVAK
LEADAARAHAAAQRDNASAQREVALTQGQRYVDALNQAHTAEIITGVQNMEQEQDVLQQQMLYTLQQRMNEMSL
>SEQF1516_EDU83686.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTITEIIGRVNTQLVDPMMVRWPLQELCDYYNDAVRAVILARPDAGASLETISCVPGARQVLPDGVIQLLDVICLSDGS
AVRPLSREVLDAQYPEWPTMKGIPECFISNDLSPRVFWLFPAPDKEISIDAVVSRIPEAVYVLTQDDDTPVPLEEAYVNP
LVEWMLFRAFSKDAAGGAESGLAAQHYQSFVEQLGIKQGADSALYARKKVFNGGGV
>SEQF1516_EDU83687.1 YjhS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATNNLKLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTLTQSPVSAFAADKLHVTDITRGATYPVLIDSIAV
EVNSTDTAA
>SEQF1516_EDU83688.1 Ant protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMMAVPFHGNSLYVVNHNGEPYVPMKPVVAGMGLAWQSQLAKLRQRFASTITEIVMVAEDGKQRNMVSMPLRKLAGWLQ
TINPNKVKPEIRDKVIRYQEECDDVLYEYWTKGFVVNPRKMSVMEELNQACADMKRDKNIASVFATGLNEWKQVKAAHVS
KIRTLVNEANMLIDFVLADTGKGKITKAD
>SEQF1516_EDU83689.1 putative tail fiber protein of bacteriophage BP-933W [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNILRKLMQSLCGCGKHDDCENGQSLTAQLRLGPADILESDENGIIPEQDRVITQVVILDADKKQIQCVVRPLQILRADG
TWENIGGMK
>SEQF1516_EDU83690.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRVLCVVIIVLAVGYGALWLATNHYRDNALTYKAQRDKKARELEQANATITDMQVRQRDVAALDAKYSRELADARAENE
TLRADVAAGRKRLRINATCSGTVREATGTSGVDNATGPRLADTAERDYFILRERLITMQKQLEGTQKYINEQCR
>SEQF1516_EDU83691.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKKPPATGMDAGGGDTYGEKIKERYFRTLVFNENSSYCQQ
>SEQF1516_EDU83692.1 lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRKLRYGLSAAVLALIAAGASAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGATRVDGKPVIPGMKLSKEKCDRVNAI
ERDKALAWVEKNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYRRINAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
VSRRDQESALACWGIDR
>SEQF1516_EDU83693.1 tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVVVSGTLKSPDGEAISGANITLTALTVSPDALSGTSASAVTREGGYYGMTMDPGEYAVSVTVKGKTAVYGRVRIEGTE
STVTLNMLLRRSLVEVSIPGELLTDFRQIQNNVADDLATIRRLNEDTATKNTQATQSKESAAASAKSASDSAKTATSRAA
EAGQKATDATEAATRAVTAAGNAEESSTRAGESEKAAGADAEKARQHAEKARLAQESAGEILKRAEAATVSAEEARRMAE
NARGPRGPQGETGPKGDVGPKGETGPVGPQGPAGPKGERGDVGAQGAVGPAGPRGEKGEQGERGPQGIPGLKGDTGERGP
KGDQGDMGPKGEKGDPGGPAGPQGPKGERGEAGPQGPMGARGERGETGPRGEPGPAGPRGERGETGPQGPRGEPGPAGSA
ANVADATTAQKGIVQLSSATDSDDETKAATPKAVKAAMDVANEAKTKAEEAAAGGGVPGPKGDKGDTGPAGPAGPKGDKG
ERGDTGPVGATGERGPAGDAGPAGPQGPKGDRGERGETGLTGNAGPQGPKGDTGAAGPAGPQGPKGETGAAGPVGATGPQ
GPKGDPGETQIRFRLGPGNIIETNSHGWFPDTDGALITGLTFLDPKDATRVQGFFQHLQVRFGDGPWQDVKGLDEVGSDT
GRTGE
>SEQF1516_EDU83694.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKTILAPSLSERVYTGTHGNESVAEGVFTVNAAEADSVIHLLSLPVGIRINSLQLVSTGGLGTATVSIKSGEHALIDNS
EAVSAKFARYVPVEPYTTQRDGELVTVTIKTAAATGTLNVLLRYTVVGY
>SEQF1516_EDU83695.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFLNQLMLYFCTVVCVLYLLSGGYRAMRDFWRRQIDKRAAEKISASQSAGSKPEEPLI
>SEQF1516_EDU83696.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSPSPPTENESKGKQKSRQCHPLTANAGSRDYGIQALLKMPDNIPASPDSGYK
>SEQF1516_EDU83697.1 tail assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVSFPSINFRSKSCFMTQTESAILVHARRCAPAESCGFVIGTPEGERYQPCVNISAEPEAYFRIAPEDWLQAEMQGEIV
ALVHSHPGGLPWLSEADRRLQIKSALPWWLVCRGEIHKFRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGITLPDFEREDD
WWRNGQNLYLDNMAATGFYRVPLSSAQAGDILLCCFGASVANHAAIYCGNGELLHHLPEQLSKRERYSEKWQRRTHSVWR
HRHWHASAFTGICNDLAAASACT
>SEQF1516_EDU83698.1 gpW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRQEELAAARAALHDLMTGKRVATVQKDGRRVEFTTTSVSDLKKYIAELEVQTGMTQRRRGPAGFYV
>SEQF1516_EDU83699.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVKLRLAVAALLLFLVVMVDFTSRIMSVLADGVLVCGIVVLLWPVIKRNSLHNA
>SEQF1516_EDU83700.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISDKLITLVKSLCVLVGISFSLMLVALFLSMAWMALTSAGLVG
>SEQF1516_EDU83701.1 minor tail protein H [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQPAGDLVIDLSLDAARFDEQMARVRRHFSSLEADARKTASTVEQGLSRQALAAQKAGISVGQYKAAMRTLPAQFTDIV
TQLAGGQNPFLIMLQQGGQISDSFGGPLSLLTLLKEELLGIRDASESSEESLSDTANALAENARNAGELGRFMSVARVAA
GGGVAVLAALAAAAWQAEQADRALLRSLILTGGAAATTTAELWKMAGVISDEAGGGIRQAAENLARLAESGKYTAGQLRI
MGETSQRWLQTVGDDAGKVEKAFEGIAADPVKALASLNQQYNFLSVSQLRHIDELERTKGKQVAVTEAMSLFADVMNARL
EQLDKAATPVEKIWDDVKTWTSDAWAWIGDHTLGALSLITDVVAGTVEQVKLLLVQGDLALAEFIQSAWETTKNVPGVGA
LFGELAEENRVFIEKTKRDELALRKSIAERDARIRQGEMGYINRSRATGVSKGPGQQEAVSRLAEELTGKKHTSPKTRSA
GEREEEQAREALLALEAELRTLEKHSGANEKISRQRRDLWKAESQYAVLKEAATKRQLSEQEKSLLAHKDETLEYKRQLA
ELGDKVEYQKRLNELAQQAVRFEEQQSAKQAAISAKARGLTDRQAQRESEAQRLRDVYGDNPAALAKATSALKNTRSAEE
QLRGSWMAGLKSGWGEWAESATDSFSQVKSAATQTFDGIAQNMAAMLTGAEADWRGFTRSVLSMMTEILLKQAMVGIVGR
IGSAIGGAFGGGASASSGTAIQAAAANFHFAIGGFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYAEGGY
VGGAGSPAQMRRAEGINFNQNNHVVIQNDGTNGQAGPQLMKAVYDMARKGAQDELRLQLRDGGMLSGSGR
>SEQF1516_EDU83702.1 phage Head-Tail Attachment [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADFDNLFDAAIARADETIRGYMGTSATMTSGERSGAVIRGVFDDPENISYAGQGVRVEGSSPSLFVRTDDVRQLRRGDT
LTINGEMFWVDRVSPDDGGSCYLWLNRGQPPAVNRRR
>SEQF1516_EDU83703.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKKYELVVKGINNYPDKITVTVAPEIGGYPSLLLPDVAISLDRTEGATLEFYEAEAKKQAKQFFMDVAAGLCEGDGPLP
EKRPVILEAQDVLITYRGKLPGIITGSLKTPPLA
>SEQF1516_EDU83704.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKITTGVSYTTSAVGTGYWLLQLLDKVSPSQWVAIGVLGSLLFGLLTYLTNLYFKIKEDRRKAARGE
>SEQF1516_EDU83705.1 prophage minor tail protein Z [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIKGLDQAIENLSRVRKNAIPAASAMAINRVATTAINQSSSQVARETKVRRKLVKERSRLKRATVRNPNARIIVKRGDL
PVIKLGIRMLGRRPDSILKAGQHRYQRAFIQRLKNGRWHVMQRVAGKNRYPIDVVKIPMAAPLKQAFDENIDRIRRERLP
GELAYALKQQLRIAIKR
>SEQF1516_EDU83706.1 TerB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFGIFKKKTRRAATEIKKFEKRDLAQVVINAAYLVACADGECEASEKAKIEQVLRNQPALSAFTSEINAISATIIGQLDT
NFKTGRRAALREIEDVKHDTREAEDVLDVAVAIAEADGEIEPEERKVLEEIAGVLGLRLENHL
>SEQF1516_EDU83707.1 putative transcriptional regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHYGKVKIVDISESVVSQYLESQHKLTRTRLTDIPLYLLLEPNNPALAAALITSQGFSGEVTDMFLMMACLSLFETDERM
SLFLSGCLSSISAKVRAIIQTDISASWTLGAIALQLHMSESLLKTKLKNEGGMFSRLLLEERMRVAVNMLCSRYGYGQAV
AEKCGYSSRSYFISVFHRYYGFPPDRYVSRQGLDY
>SEQF1516_EDU83708.1 Ant protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMMAVPFHGNSLYVVNHNGEPYVPMKPVVAGMGLAWQSQLAKLRQRFASTITEIVMVAEDGKQRNMVSMPLRKLAGWLQ
TINPNKVKPEIRDKVIRYQEECDDVLYEYWTKGFVVNPRKMSVMEELNQACADMKRDKNIASVFATGLNEWKQVKAAHVS
KIRTLVNEANMLIDFVLADTGKGKITKAD
>SEQF1516_EDU83709.1 DNA packaging protein FI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKDELIARLRSLGEQLNRDVSLTGTKEELALRVAELEEELDDTDETAGQDTPLSRENVLTGHENEVGSAQPDTVILDTS
ELVTVVALVKLHTDALHVTRDEPVAFVLPGTAFRVSAGVAAEMTERGLARMQ
>SEQF1516_EDU83710.1 phage portal protein, lambda family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKMSTIPTLLGPDGMTSLREYAGYHGGGSGFGGQLRAWNPPGESVDAALLPNFTRGNARADDLVRNNGYAANAIQLHQDH
IVGSFFRLSHRPSWRYLGIGEEEARAFSREVEAAWKEFAEDDCCCIDVERKRTFTMMIREGVAMHAFNGELFVQATWDTR
PSRLFRTQFRMVSPKRISNPNNTSDSRNCRAGVQINDSGAALGYYVSEDGYPGWMPQKWTWIPRELPGGRASFIHVFEPV
EDGQTRGANVFYSVMEQMKMLDTLQNTQLQSAIVKAMYAATIESELDTQSAMDFILGANSQEQRERLTGWIGEIAAYYAA
APVRLGGAKVPHLMPGDSLNLQTAQDTDNGYSVFEQSLLRYIAAGLGVSYEQLSRNYAQMSYSTARASANESWAYFMGRR
KFVASRQASQMFLCWLEEAIVRRVVTLPSKARFSFQEARSAWGNCDWIGSGRMAIDGLKEVQEAVMLIEAGLSTYEKECA
KRGDDYQEIFAQQVRETMERRAAGLKPPAWAAAAFESGLRQSTEEEKSDSRAA
>SEQF1516_EDU83711.1 phage minor tail protein U [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHTDIRAAVLDALELHEHGATLFDGRPVVFDEEDFPAVAVYLTDAEYTGEELDADTWRATLHIEVFLPAQVPDSELDQW
MESRIYPAVTAIPALADLITTMVTQGYEYRRDDDMALWSSADLTYSITYEM
>SEQF1516_EDU83712.1 bacteriophage lambda head decoration protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSKETFTHYQPLGNSDPAHTATAPGGLSAKAPAMTPLMLDTSSRKLVAWDGTTDGAAVGILAVAADQTSTTLTFYKSGT
FRYEDVLWPEAASDETKKRTAFAGTAISIV
>SEQF1516_EDU83713.1 phage major capsid protein E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLFLRDFFMSMYTTAQLLAANEQKFKFDPLFLRLFFRESYPFTTEKVYLSQIPGLVNMALYVSPIVSGEVIRSRGGSTS
EFTPGYVKPKHEVNPQMTLRRLPDEDPQNLADPAYRRRRIIMQNMRDEELAIAQVEEMQAVSAVLKGKYTMTGEAFDPVE
VDMGRSAANNITQSGGTEWSKRDKSTYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVREKLDTRRGSHSELETA
VKDLGKAVSYKGMYGDVAIVVYSGQYVENGVKKNFLPDNTMVLGNTQARGLRTYGCIQDADAQREGINASARYPKNWVTT
GDPAREFTMIQSAPLMLLADPDEFVSVQLA
>SEQF1516_EDU83714.1 phage lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAKIRYGLSAAVLALIGAGASAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGATRGDGKPVIPGMKLSKEKCDRVNAI
ERDKALAWVEKNIRVPLTEPQKAGIASFCPYNIGPGKCFPSTFYRRINAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
VSRRDQESALACWGIDR
>SEQF1516_EDU83715.1 terminase small subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVNKKKLAEIFNVDPRTIERWQSQGLPCVSGGGKGVESVFDTATAIQWYAQREADIENEKLRKEVEDYRAASEADLQPG
TIEYECHRLTRAQADAQELKNARDSAEVVETAFCTFVLSRIAGEIASILDGIPLSVQRRFPELENRHVDFLKRDIIKAMN
KAAALDELIPGLLSEYIEQSD
>SEQF1516_EDU83716.1 phage minor tail protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDIHEESLNESVKSEQSPRVVLWEIDLTAQGGERYFFCNELNEKGEAVTWQGRQYQAYPIDGSGFEMNGKGSSARPSLT
VSNLFGLVTGMAEDLQSLVGATVVRRRVYARFLDAVNFVAGNPEADPEQELTDRWVVEQMSSLTAMTASFVLATPTETDG
ALFPGRIMLANTCMWDYRGDECGYNGPAVADEFDNPTTDIRKDRCSKCMRGCEMRGMVANFGGFLSINKLSQ
>SEQF1516_EDU83717.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNDFCDKYFEYYLQVNGVGHMDRNITIEYEVYARIVWAEKAKTW
>SEQF1516_EDU83718.1 minor capsid protein C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAELRNLPHIASMAFNEPLMLEPAYARVFFCALAGQLGISRLTDAVSGDSLTAGEAPAALALSGDDDGPRQARSYQVMN
GIAVLPVSGTLVSRTRALQPYSGMTGYNGIIARLQQAASDPMVDGILLDMDTPGGMVAGAFDCADIIARVRDIKPVWALA
NDMNCSAGQLLASAASRRLVTQTARTGSIGVMMAHSNYGAALEKQGVEITLIYSGSHKVDGNPYSHLPGDVRETLQSRMD
ATRRMFAQKVSAYTGLSVQAVLDTEAAVYSGQEAIDAGLADELVNSTDAITVMRDALDARKSRLSGGRMTKETQSTTVSA
TASQADVTGVVPATEGENASAAQPDVNAQITAAVAAENSRIMGILNCEEAHGREEQARVLAETPGMTVETARRILAAAPQ
SAQARSDTALDRLMQGAPAPLAAGNPASDAVNDLLNTPV
>SEQF1516_EDU83719.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKQQDMTETARVVFNELSVTEPATVGEIAQNTYLSRERCQLILTQLVMAGLADYQCGCYRRIQS
>SEQF1516_EDU83720.1 hypothetical protein ECH7EC4501_1191 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAELLFGFEYIVSVFCSVIALSIKMPDMICFSLLFSFFVYYFYCFYIISFLLLSY
>SEQF1516_EDU83721.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEQINIALDLKGSGNFSAWVIEACRRRLINEKYSQFVPNKDKHDQRTCSDRFT
>SEQF1516_EDU83722.1 phage tail assembly protein T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAGMTSTEYADWRRFYCTHYFQDTQLDAHFSGLMYAVLSLFFGDPDMHPADFSLLAPACEEEQTEMPDEEEMLMQKATG
VAGGVRFGGDGGRDISPSADVVDVSEDDVALMMASAGISGGVRYVPASG
>SEQF1516_EDU83723.1 phage terminase large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNISNSQIDILRRDVRAGLRALFRPEPQTAVEWADASYYLPKESAYQEGRWETLPFQRAIMNAMGSDYIREVNVVKSARV
GYSKMLLGVYAYFIEHKQRNTLIWLPTDGDAENFMKTHVEPTIRDIPSLLSLAPWYGKKHRDNTLTMKRFTNGRGFWCLG
GKAAKNYREKSVDVAGYDELAAFDEDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVRGTCQIERAASESPHFMRFHVAC
PHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEHNACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPD
SVTFHIWTAYSPFTTWVQIVKDWMKTKGDTGKRKTFVNTTLGETWEAKIGERPDAEVMAERKEHYSASVPDRVAYLTAGI
DSQLDRYEMRVWGWGPGEESWLIDRQIIMGRHDDEQTLLRVDEAINKTYTRRNGAEMSVSRICWDTGGIDPTIVYERSKK
HGLFRVIPIKGASVYGKPVASMPRKRNKNGVYLTEIGTDTAKEQIYNRFTLTPEGDEPLPGAVHFPNNPDIFDLTEAQQL
TAEEQVEKWVDGRKKILWDSKKRRNEALDCFVYALAALRISISRWQLDLSALLASLQEEDGAATNKKTLAEYARALSGED
E
>SEQF1516_EDU83724.1 phage minor tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTFRWKVKPDMEVNSQPSVREVRFGDGYSQRMAAGLNADLKTYRVTLSVTREEARHLEAFLAEHGGWKAFLWKPPYAYR
QIKVTCAGWSARVGMLRVEFSAEFKQVVN
>SEQF1516_EDU83725.1 hypothetical protein ECH7EC4501_1174 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHLVARTTEPGLSDNVSFSRKILIGEQTMITEQTTAIIILLSLAIG
>SEQF1516_EDU83726.1 major tail protein V [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATPNPLEPVKGAGTTLWVYNGKGDAYANPLSDDDWQRLAKVKDLTPGEMTAEPYDDNYLDDEDADWTATGQGQKSAGDT
SFTLAWKPGEEGQKGLIGWFESGDVRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGKPSVAEERSEITP
ATAIKVTPTSGTVAKGKTTTLTVSFEPESATDKTFRAVSADPSKATISVKDMTITVNGVATGKVQIPVVSGNGQFAAVAE
VTVTEAGAAG
>SEQF1516_EDU83727.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSAFTVILLVVCGALSLGLNHYRDNAITYKEQRDKKVSELELANATITDMQQRQRDVAALDARYSRELADARAENETLR
ADVAAGRKRLRINANCPGSLRKAPITSGVDNATGPRLAEAAERDYFILRERLMAMQKQLEGAQEYIRTQCIP
>SEQF1516_EDU83728.1 PTS system IIA component domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLGWVITCHDDRAQEILDVLEKKHGALLQCRAVNFWRGLSSNMLSRMMCDALHEADSGEGVIFLTDIAGAPPYRVASLLS
HKHSRCEVISGVTLPLIEQMMACRETMTSSEFRERIVELGAPEVSSIWHQQQKNPPFVLKHNLYEY
>SEQF1516_EDU83729.1 hypothetical protein ECH7EC4501_5568 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFALQHRANHNFYLSTLSLTKQAVPALRKFSRSIARFLFSVYSSDGICISSLRTAPKRAMYRL
>SEQF1516_EDU83730.1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILTVSSFYRTPPLGPQDQPDYLNAAVALETTLAPEELLNHTQQIELQ
QGRVRKAERWGPRTLDLDIMLFGNETINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGETLREILTSLAVLQPAIWY
>SEQF1516_EDU83731.1 S-adenosylmethionine decarboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYNANRLTEILSETCSIIGANILNIARQDYEPQGASVTI
LVSEEPVDPKLIDKTEHPGPLPETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKMLLKEFDLKHYMFHTKPEDLTDSE
RQEITAALWKEMREIYYGRNMPAV
>SEQF1516_EDU83732.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDAPSTTPHDAVFKQFLMHAETARDFLEIHLPVELRELCDLNTLHLESGSFIEESLKGHSTDVLYSVQMQGNPGYLHVVI
EHQSKPDKKMAFRMMRYSIAAMHRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNSPFPLVDITI
TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSESQLVAMQNYMLQRGHTEQADLFYGVLRDRETGGKS
MMTLAQWFEEKGIEKGIQQGRQEERQEFAQRFLSKGMSREDVAEMTNLSLAEIDRLIN
>SEQF1516_EDU83733.1 putative fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLKVIATLIATVAVGVSFNSNFASASTTSASLTVNSNLTMGTCSAQIMDNSNKVINEVVFGNVYISELGAKSKVQQFKI
RFSNCSGLPQNSAQIVLAPNGISCAGSQSSSAGFSNKFTDASAATRTAVEVWTTDTPESNGSTQFHCAQKIPVPVTLPAD
TTTQPYDYPLSARMTVAEGRLVTDVRPGNFRSPTTFTITYQ
>SEQF1516_EDU83734.1 fimbrial usher protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQFTHQKSRIPKKTLLAACCALFYSSNGAAADTVEYDSSFLMGTGASTIDVKRYAQGNPTPPGLYNVRVFVNGQATSSL
EIPFVDIGENSAAACLTHKNLAQLHIKQPEQPVTLLAREGEEEDCLDLAKSYEKADVCFDGSDQFLDLTIPQAYVLKSYG
GYVDPSLWESGINAATLAYTLNAYHTSSDNDNSDSVYGAFNSGINLGAWHFRARGNYNWTTDNGSDFDFQDRYLQRDIPA
IRSQIIMGDAYTTGETFDSVNVRGVRLYSDSRMLPSALASYAPTIRGVANSNAKVTVTQSGYKIYETTVPPGEFVIDDIS
PSGFGSELVVTIEEADGSKRTFTQPFSSVVQMQRPGVGRWDFSAGKVIDDSLRSEPNMGQASYYYGLNNLFTGYTGIQFT
DNNYLAGLLGVGINTSIGAFAVDVTHSRAEIPDDKTYQGQSYRVTWNKLFQDTGTSFNLAAYRYSTQDYLGLHDALVLID
DAKHLSADEDKNTMQTYSRMKNQFTVSINQPLNIAYEDYGSLFISGSWTYYWAANNSRTEYNVGYSKSVSWGSFSVNLQR
SWNEDGEKDDAMYVSVSVPIENILGGKRKSSGFRNLNTQLNTDFDGSHQLNVNSSGNTENNLVNYSVNAGYSLDKNAGDL
ASVGGYLNYESGLGGISASASATSDNSQQYSISTDGGFVLHSGGLTFTNNSFSSNDTLVLINALGAKGARINNSNNEIDR
WGYAVTSSVSPYRENRVGLNIETLENDVELKSTSATTVPRSGSVVLTRFETDEGRSAVLNITAANGKSIPFAAEVYQGEV
MIGSMGQGGQAFVRGINDSGELIVRWYENNQTIDCKLHYQFPAQPQTQGSTNTLLLNNLTCQVANH
>SEQF1516_EDU83735.1 3-methyl-2-oxobutanoate hydroxymethyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPTTIASLQKCKQEKKRFATITAYDYSFAKLFAEEGLNVMLVGDSLGMTVQGHESTLPVTVEDIAYHTTAVRRGAPNCL
LLADLPFMAYATPEQAFENAATVMRAGANMVKIEGGEWLVETVKMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAS
DRLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDAFGITGGHIPKFAKNFLAETGDI
RAAVRQYMAEVESGVYPGEEHSFH
>SEQF1516_EDU83736.1 spermidine synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFGRVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKH
VLIIGGGDGAMLREVTRHKNVESITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCT
DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGFYQAAIPTYYGGIMTFAWATDND
ALRHLSTEIIQARFLASGLKCRYYNPAVHTAAFALPQYLQDALASQPS
>SEQF1516_EDU83737.1 enterobactin synthetase component D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVVHAGCGVNALSSLQNCAKSMDCTGNVGLISVAHQADLRLSSV
>SEQF1516_EDU83738.1 ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGNLIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVA
SSFFGAKFQRNIEELLVAPVPTHVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGFLGINDVPLVTTFGVLVVFIVAF
YLICWSLIQRGRGLRS
>SEQF1516_EDU83739.1 putative fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLCRHHKIVHFLGLATALITPFAYSGQDVDLTAKIVPSTCQVEVSNNGVVDLGTVTLDYFADNVTPTTDYAGGKTFNVNV
VSCDNIQTTQSQMKLDFQPQAGSLAQANNQIFSNEYEQQATGAKNVGIVIFSAQPNQQTFNVRGTDGSSTAIYSVAPGNA
VPSTWTFYSRMQRVNNALPPESGMVRSQVIVNVSYE
>SEQF1516_EDU83740.1 aspartate 1-decarboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAIDIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCAS
VGDIVIIASFVTMPDEEARTWRPNVAYFEGDNEMKRTAKAIPVQVA
>SEQF1516_EDU83741.1 carbonic anhydrase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSDSRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSV
VQYAVDVLEVEHIIICGHYGCGGVQAAVENPELGLINNWLLHIRDIWFKHSSLLDEMPQERRLDTLCELNVMEQVYNLGH
STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHANHK
>SEQF1516_EDU83742.1 copper oxidase CueO [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDARNRIQLTIGAGQSTFGEKTATTWGYNGNLLGPAVKL
QRGKAVTVDIYNQLTEETTLHWHGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLV
VIEDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNGAIYPQHAAPRGWLRLRLLNGCN
ARSLNFATSDNRPLYVIASDGGLLPEPVKVNELPVLMGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQ
PIAISASGALPDTLSSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMVGMDHSQMMGHMGHGNMNHMNHGG
KFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGTQFRILSENGKPPAAHRAGWKDTVKVEGNVS
EVLVKFNHDAPKERAYMAHCHLLEHEDTGMMLGFTV
>SEQF1516_EDU83743.1 poly(A) polymerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSREESEAEQAVARPQVTVIPREQHAISRKDISENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQ
VRKLFRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGSIEEDAQRRDFTINSLYYS
VADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLRAVRFAAKLGMRISPETAEPIPRLATLLNDIPPARLFEESL
KLLQAGYGYETYKLLCEYHLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLLETAQ
KIAQESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQGKRAWKLLEHPKFRAAYDLLALRAEVE
RNAELQRLVKWWGEFQVSAPPDQKGMLNELDEEPSPRRRTRRPRKRAPRREGTA
>SEQF1516_EDU83744.1 polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVTVGNIRAGQIIAVEPTAASYYAFNFGFDKGFIDKGHL
EPVQGRQKVEDGLGDLNKPLSNQNLVTWKDTPVYNAPSVGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
ALDAQPDNGLPVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMVQLEGYVKNKINLPARAVVITFDD
GLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKWEPKSLQFMSVSELNEIRDVFDFQSHTHFLHRVDGYRRPILLSRS
EHNILFDFARSRRALAQFNPHVWYLSYPFGGFNDKAVKAANDAGFHLAVTTMKGKVKPGDNPLLLKRLYILRTDSLETMS
RLVSNQPQG
>SEQF1516_EDU83745.1 putative fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTGSNDEYSLTIPDVGLDKVATAAPEAQANFKLKASDCSNGYSKIFTTLTGTTVSGKLIVNEATSGAAGVGMGIKRRDTA
DSTFFTPNNTDKFEWSADEKASGVPLTVALRETTAGAGRTGAFQAKATFNFTYE
>SEQF1516_EDU83746.1 gram-negative pili assembly chaperone [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFPLVKKTVSALFVSTLLASAPAFADIIISGTRIIYNADKKDVNVRLENKGNRPLLIQNWLDTGDDNADPSQIKVPFTAT
PPVSRVEPKRGQTVKVMYTGATALPKDRESVYWFNVLEVPPKPKDAEADKNLLQLAFRTRIKLFYRPSGLQGEPAEAPAK
ITWKLNNAQLQANNPTPYYVSFNEVKLESGGKTYNVNSSMVTPFSQASFGVTSLPGSVSSGKVVFKAINDFGGNIDGSAT
F
>SEQF1516_EDU83747.1 putative fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQRKGNKLLIQLCSVILLFFTTSWYALANECYIERNAEGDYHMKISSTQLSLASQMVEVPTEIAEATWDVNIQLRGDAIG
CKSLGDSKAVHFLNTADPSLISTYTTTNGAALLKTTVPGIVYSVELLCLSCGAADELDLWLPAQSGADNFIPSTQTKWAY
EYSDQSWYLRFRLFITPEFKPKNGVSSGTTIAGKIASWYIGTNDQPWINFYIDNDSLKFFVDEPTCATVALAQDQGNVSG
NQVTLGNSYVSEVKNGLTREIPFSIRAEYCYASKITVKLKAANKPSDATLVGKTTGSASGVAVKVNSTYDNSKVLLKADG
SNTVDYNFAAWSNNLLFLPFTAQLVPDGSGNAVGVGTFSGNATFSFTYE
>SEQF1516_EDU83748.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKNDCGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKA
LGEDSYRDLSGIGIPVAKKCKALARDSLSLLAYVK
>SEQF1516_EDU83749.1 quinoprotein glucose dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYPIAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGV
WEVGFDFWALTPRSDILVFFGIWLILPFVWRRLVIPASGAVAALVVALLISGSILTWAGFNDPQEINGTLSADATPAEAI
SPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEVTPIKVGDTLYLCTAHQRLFALD
AASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAETASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLN
LQSNMPDTKPGLYEPTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSDEHTFTFNS
PNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATTGKLAWSYQTVHHDLWDMDLPAQPTLADITV
NGQKVPVIYAPAKTGNIFVLDRRNGELVVPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCR
VMFHQMRYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGNPMEQPKDAKGTGTESG
IQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEVVWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAG
NVLFIAATADNYLRAYNMSNGEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK
>SEQF1516_EDU83750.1 putative fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKALLAAALVMASGSALAVDGGHIDFNGMVQSGTCKVGVVDTGMHSVTTDGVVTLDTANVTDTFAEVSATAVGLLPKEF
MISVECDPGAPKNAELTMGSASYANTSGTLNNNMNITVNGIAPAQNVNIAVHNMKNKAGAAEIKQVHMNNSSEVQELTLD
AEGKGQYVFNASYVKAPNSPAVTAGHVTTNALYTVAYK
>SEQF1516_EDU83751.1 pantoate--beta-alanine ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEAKARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCE
KLNKRKVDLVFAPSVKEIYPNGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
KMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAGERDLDEIIAIAGQELNEKGFRA
DDIQIRDADTLLEVSETSKRAVILVAAWLGDARLIDNKMVELA
>SEQF1516_EDU83752.1 hypoxanthine phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRGSFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDV
KILKDLDEDIRGKDVLIVEDIIDSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
AQRYRHLPYIGKVILLDE
>SEQF1516_EDU83753.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIALELQQLKKNYPGGVQALRGIDLQVEAGDFYALLGPNGAGKSTTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQL
GLVPQEFNFNPFETVQQIVVNQAGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENTSMKALLAKLKSETFILDLAPKS
PLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLSEQGIQVLSMRNKANRLEELFVSLVNEKQGDRA
>SEQF1516_EDU83754.1 cytochrome c-type protein napC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGNSDRKPGLIKRLWKWWRTPSRLALGTLLLIGFVGGIVFWGGFNTGMEKANTEEFCISCHEMRNTVYQEYMDSVHYNNR
SGVRATCPDCHVPHEFVPKMIRKLKASKELYGKIFGVIDTPQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFEYMDTTA
QKSVAAKMHDQAVKDGQTCIDCHKGIAHKLPDMREVEPGF
>SEQF1516_EDU83755.1 cytochrome c-type biogenesis family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFLLGVLMLMISGSALATIDVLQFKDEAQEQQFRQLTEELRCPKCQNNSIADSNSMIATDLRQKVYELMQEGKSKKEIV
DYMVARYGNFVTYDPPLTPLTVLLWVLPVVAIGIGGWVIYARSRRRVRVVPEAFPEQSVPEGKRAGYVVYLPGIVVALIV
AGVSYYQTGNYQQVKIWQQATAQAPALLDRALDPKADPLNEEEMSRLALGMRTQLQKNPGDIEGWIMLGRVGMALGNASI
ATDAYATAYRLDPKNSDATLGYAEALTRSSDPNDNRLGGELLRQLVRTDHSNIRVLSMYAFNAFEQQRFGEAVAAWEMML
KLLPANDTRRAVIERSIAQAMQHLSPQESK
>SEQF1516_EDU83756.1 heme exporter protein C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWKTLHQLAIPPRLYQICGWFIPWLAIASVVVLTVGWIWGFGFAPADYQQGNSYRIIYLHVPAAIWSMGIYASMAVAAFI
GLVWQMKMANLAVAAMAPIGAVFTFIALVTGSAWGKPMWGTWWVWDARLTSELVLLFLYVGVIALWHAFDDRRLAGRAAG
ILVLIGVVNLPIIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWSIFGFLLLSATLTLMRMRNLILLMEKRRPWVSELIL
KRGRK
>SEQF1516_EDU83757.1 ecotin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQVIQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLE
SKTLEGWGYDYYVFDKVSSPVSTMMACPDGKKEKKFVTAYLGDTGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAV
VR
>SEQF1516_EDU83758.1 alkylated DNA repair protein AlkB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDLFADAEPWQEPLAAGAVILRRFAFNAAEQLIRDINDVASQSPFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSP
IDPQTNKPWPAMPQSFHNLCQRAATAAGYPDFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLK
RNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTTDCRYNLTFRQAGKKE
>SEQF1516_EDU83759.1 periplasmic nitrate reductase, NapG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRSAKPQNGRRRFLRDVVRTAGGLAAVGVALGLQQQTARASGVRLRPPGAINENAFASACVRCGQCVQACPYDTLKLAT
LASGLSAGTPYFVARDIPCEMCEDIPCAKVCPSGALDREIESIDDARMGLVVLVDQENCLNFQGLRCDVCYRECPKIDEA
ITLELERNTRTGKHARFLPTVHSDACTGCGKCEKVCVLEQPAIKVLPLSLAKGELGHHYRFGWLEGNNGKS
>SEQF1516_EDU83760.1 periplasmic nitrate reductase, NapH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANRKRDAGREALEKKGWWRSHRWLVLRRLCQFFVLGMFLSGPWFGVWILHGNYSSSLLFDTVPLTDPLMTLQSLASGHL
PATVALTGAVIITVLYALAGKRLFCSWVCPLNPITDLANWLRRRFDLNQSATIPRHIRYVLLVVILVGSALTGTLIWEWI
NPVSLMGRSLVMGFGSGALLILALFLFDLLVVEHGWCGHICPVGALYGVLGSKGVITVAASDRQKCNRCMDCFHVCPEPH
VLRAPVLDEQSPVQVTSRDCMTCGRCVDVCSEDVFTITTRWSSGAKS
>SEQF1516_EDU83761.1 periplasmic nitrate reductase, diheme cytochrome c subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSHDLKKALCQWTAMLALVVSGAVWAANGVDFSQSPEVSGTQEGAIRMPKEQDRMPLNYVNQPPMIPHSVEGYQVTTNT
NRCLQCHGVESYRTTGAPRISPTHFMDSDGKVGAEVAPRRYFCLQCHVPQADTAPIVGNTFTPSKGYGK
>SEQF1516_EDU83762.1 thiamine biosynthesis lipoprotein ApbE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEISFTRVALLAAALFFVGCDQKPQPAKTHATEVTVLEGKTMGTFWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYK
KDSALMRFNDSQSLSPWPVSEAMADIVTTSLRIGAKTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQH
LTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLARLMEQEGISRYLVSVGGALNSRGMNGEGLPWRVAIQKPTDKENA
VQAVVDINGHGISTSGSYRNYYELDGKRLSHVIDPQTGRPIEHNLVSVTVIAPTALEADAWDTGLMVLGPEKAKEVVRRE
GLAVYMITKEGDSFKTWMSPQFKSFLVSEKN
>SEQF1516_EDU83763.1 putative autotransporter, IS5K-containing [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHQSGSVSLCRSAISVLVATALYSPIALASTVEYGETVDGVVLEKDIQLVYGTANNTKINPGGEQHIKEFGISSNTEING
GYQYIEMNGTAEYSVLNDGYQIVQMGGAANQTTLNNGVLQVYGAANDPTIKGGRLIVEKDGITVLAAIEKGGLLEVKEGG
LAIAVDQKAGGAIKASTRVMEVFGTNRLGQFEIKNGIANNMLLENGGSLRVEENDFAYNTTVDSGGLLEVMDGGTATGVD
KKAGGKLIVSTNALEVSGTNSKGQFSIKDGVSKNYELDDGSGLIVMEDTQAIDTILDEHATMQSLGKDTGTRVQANAVYD
LGRSDQNGSITYSSKAISENMVINNGRANVWAGTMVNVSVRGNDGILEVMKPQINYAPAMLVGKVVVSEGASLRTHGAVD
TSKADVSLENSAWTIIADITTTNQNTRLNLANLAMSGANVIMMDESVTRSSVTASAENFTTLTTNTLSGNGNFYMRTDMA
NHQSDQLNVTGQATGDFKIFVTDTGASPAAGDSLTLVTTGGGDAAFTLGNAGGVVDIGTYEYTLLDNGNHSWSLAENRAQ
ITPSTTDVLNMAAAQPLVFDAELDTVRERLGSVKGVSYDTAMWSSAINTRNNVTTDAGAGFEQTLTGLTLGIDSRFSREE
SSTIRGLFFGYSHSDIGFDRGGKGNVDSYTLGAYAGWEHQNGAYVDGVVKVDRFANTIHGKMSNGATAFGDYNSNGAGAH
VESGFRWVDGLWSVRPYLAFTGFTTDGQDYTLSNGMRADVGNTRILRAEAGTAVSYHMDLQNGTTLEPWLKAAVRQEYAD
SNQVKVNDDGKFNNDVAGTRGVYQAGIRSSFTPTLSGHLSVSYGNGAGVESPWNTQAGVVWTF
>SEQF1516_EDU83764.1 nitrate/nitrite response regulator NarP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVT
AQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLHEREMFGAEEDPFSVLTERELD
VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ
>SEQF1516_EDU83765.1 cytochrome c-type biogenesis protein CcmE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEILYGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKV
TFTIYDAEGSVDVSYEGILPDLFREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS
>SEQF1516_EDU83766.1 ABC transporter ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETADTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFV
YRLRSEFIKRILDTHVERIEQLGSASLLAGLTSDVRNITIAFVRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAVT
IWGGFVLVARVYKHMATLRETEDKLYTDFQTVLEGRKELTLNRERAEYVFNNLYIPDAQEYRHHIIRADTFHLSAVNWSN
IMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLRTPLLSAVGALPTLLTAQVAFNKLNKFALAPFKAEFPRPQAFPSW
QTLELRNVTFAYQDNAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVSGEQPEDYRKLFS
AVFTDVWLFDQLLGPEGKPANPQLVEKWLAQLKMAHKLELRNGRIVNLKLSKGQKKRVALLLALAEERDIILLDEWAADQ
DPHFRREFYQVLLSLMQEMGKTIFAISHDDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVARTA
>SEQF1516_EDU83767.1 hypothetical protein ECH7EC4501_4577 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHTPIEVKPVAGSKEWREAWQKRAFAHISNGYKYIYIAINSPEIFLLVCSLIRI
>SEQF1516_EDU83768.1 malate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSATLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAG
TGHSALMELNYTPQNADGSISIEKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIASLQKKSNFSLQLSSEVRALKRND
DNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLLQESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGA
PPMSVPHIDTRVLDGKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVMLSEEDRFEA
LKEYYPQAKKEDWRLWQAGQRVQIIKRDADKGGVLRLGTEVVSDQQGTIAALLGASPGASTAAPIMLNLLEKVFGDRVSS
PQWQATLKAIVPSYGRKLNGDVAATERELQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL
>SEQF1516_EDU83769.1 regulatory protein Ada [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNATCLTDDQRWQSVLARDPNADGEFVFAVRTTGIFCRPSCRARHALRENVSFYANASEALAAGFRPCKRCQPDKANAQ
QHRLDKITHACRLLEQETPVTLEALADQVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLRESLAKGESVTTSILNAGFP
DSSSYYHKADETLGMTAKQFRHGGENLAVRYALADCELGRCLVAESERGICAILLGDDDATLISELQQMFPAADNAPADL
TFQQHVREVIASLNQRDTPLTLPLDIRGTAFQQQVWQALRTIPCGETVSYQQLANAIGKPKAVRAVASACAANKLAIVIP
CHRVVRGDGTLSGYRWGVSRKAQLLRREAENEER
>SEQF1516_EDU83770.1 heme exporter protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHRAILRGVAQQRAREARLRAAQQQEAA
>SEQF1516_EDU83771.1 periplasmic nitrate reductase, large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKAPCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLN
CIKGYFLPKIMYGKDRLTQPLLRMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAAS
KLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAEMHPILWSRITNRRLSNQDVTVA
VLSTYQHRSFELADNGIIFTPQSDLVILNYIANYIIQNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDA
SEPMSFEDYKAFVAEYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHLLTGKISQP
GCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPSGTIPAKIGLHAVAQDRALKDGKLNVYWTMC
TNNMQAGPNINEERMPGWRDPRNFIIVSDPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLW
QLVQFSRRFKTEEVWPEELLAKKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDESRELGFYLQKGLFEEYAWFGRGH
GHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGEGYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGR
VLEHWHTGSMTRRVPELHRAFPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAAQL
VNKLTLDATDPLSKETDFKKCAVKLEKV
>SEQF1516_EDU83772.1 NapD protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHTNWQVCSLVVQAKSERISDISTQLNAFPGCEVAVSDAPSGQLIVVVEAEDSETLIQTIESVRNVEGVLAVSLVYHQQE
EQGEETP
>SEQF1516_EDU83773.1 ferredoxin-type protein NapF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACINACENNILQRGAGGYPSVNFKNNECSFCYACAQACP
ESLFSPRHTRAWDLQFTIGDACLAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEY
LHAH
>SEQF1516_EDU83774.1 heme ABC exporter, ATP-binding protein CcmA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLEVRELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTTLLRLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIG
HQPGIKTRLTALENLHFYHRDGDTAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAIDVN
GVDRLTQRMAQHTEQGGIVILTTHQPLNVAESKIRRISLTQTRAV
>SEQF1516_EDU83775.1 thiol:disulfide interchange protein DsbE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRKVLLIPLIIFLAIAAALLWQLARNAEGDDPTNLESALIGKPVPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWC
PTCRAEHQYLNQLSAQGIRVVGMNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHA
GDLNPRVWEEEIKPLWEKYSKEAAQ
>SEQF1516_EDU83776.1 heme exporter protein CcmB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQLLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLE
QLMLLPLPLPAVVLAKVMAHWMVTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRISIQ
>SEQF1516_EDU83777.1 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNQPTEIAIVGGGMVGGALALGLAQHGFTVTVIEHAEPAPFVADSQPDVRISAISAASVSLLKGLGVWDAVQAMRCHPY
RRLETWEWETAHVVFDAAELKLPLLGYMVENTVLQQALWQALEAHPKVTLRVPTSLIALHRDNDLQELELKGGEVIRAKL
VIGADGANSQVRQMAGIGVHAWQYAQSCMLISVQCENDPGDSTWQQFTPDGPRAFLPLFDNWASLVWYDSPARIRQLQNM
NMAQLQVEIAKHFPSRLGYVTPLAAGAFPLTRRHALQYVQPGLALVGDAAHTIHPLAGQGVNLGYRDVDALIDVLVNARS
YGEAWASYPVLKRYQMRRMADNFIMQSGMDLFYAGFSNNLPPLRFVRNLGLMAAERAGVLKRQALKYALGL
>SEQF1516_EDU83778.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKKLMYIFTIFIVAAITCISQPKKTTLRDKAMVNYAFDYLSSPGSLPFTTAATELSAIHGHSTSQYRLGEFYLHGSDGK
PLDYTQARYWYEQSAEQENPRAQSKLGWIYLKGLGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGINVNHYESQ
KWLKLAAKQHYKNAERLLAGLPAH
>SEQF1516_EDU83779.1 glutamate/aspartate ABC transporter, permease protein GltK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVMRLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVP
GFLQNVLGLSPKNDIRLISAMVAFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT
QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSYLKRRTA
>SEQF1516_EDU83780.1 tRNA-i(6)A37 thiotransferase enzyme MiaB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVLLLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGV
GGCVASQEGEHIRQRAHYVDIIFGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKY
CTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSFADLLRLVAAIDGIDRIRFTTSH
PIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNLMGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEK
TMKLIADVNFDMSYSFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGTSRKSIMEL
SGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRVAETPESVIARTRKENDLGVGYYQP
>SEQF1516_EDU83781.1 nicotinate (nicotinamide) nucleotide adenylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPPHRPQPEANSVQRKHMLELAIADKPLFTLDERELKRN
APSYTAQTLKEWRQEQGPDVPLAFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPED
LHLQPAGKIYLAETPWFNISATIIRERLQNGESCDDLLPEPVLTYINQQGLYR
>SEQF1516_EDU83782.1 DNA polymerase III, delta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAVRQVAAAQGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASRQTL
LLLLPENGPNAAINEQLLTLTGLLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTCQTPEQAQLPRWVAARAKQLNL
ELDDAANQVLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWVDALLMGKSKRALHILQQLRLEG
SEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKHRVWQNRRGMMGEALNRLSQPQLRQAVQLLTRTELTLKQDYSQSV
WAELEGLSLLLCHKPLADVFIDG
>SEQF1516_EDU83783.1 glutamate/aspartate ABC transporter, permease protein GltJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIDWNWGIFLQQAPFGNTTYLGWIWSGFQVTIALSICAWIIAFLVGSFFGILRTVPNRFLSGLGTLYVELFRNVPLIVQ
FFTWYLVIPELLPEKIGMWFKAELDPNIQFFLSSMLCLGLFTAARVCEQVRAAIQSLPRGQKNAALAMGLTLPQAYRYVL
LPNAYRVIVPPMTSEMMNLVKNSAIASTIGLVDMAAQASKLLDYSAHAWESFTAITLAYVFINAFIMLVMTLVERKVRLP
GNMGGK
>SEQF1516_EDU83784.1 hypothetical protein ECH7EC4501_6115 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAWVIISRNSQARRSGGPCFFSLYPHLYRNACAFFLWRE
>SEQF1516_EDU83785.1 hypothetical protein ECH7EC4501_6127 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSAKSRCCLVDDVFFAPMPDAAFTPHPAAVIMGSQWLNKRSPAA
>SEQF1516_EDU83786.1 magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDSGQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMI
TLKRNQTLDECLDVIIESAHSRFPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS
QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALASIEDFNEAFGTHFSDEEVDTIG
GLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQVHVKIPDDSPQPKLDE
>SEQF1516_EDU83787.1 glutamate/aspartate ABC transporter, periplasmic glutamate/aspartate-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLRKPATAILALALSAGLAQADDAAPAAGSTLDKIAKNGVIVVGHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKK
LNKPDLQVKLIPITSQNRIPLLQNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGDDIKDFADLKGKAVVVTS
GTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKKPDNWDIVGKPQSQEAYGCMLRK
DDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPPKNLNMNFELSDEMKALFKEPNDKALN
>SEQF1516_EDU83788.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDMESQKILFALSTPMEIRNECCLPSHSSPKMYLGTRFFDLSSSWGIDDRDDLLRTIHRMIDNGHAARLAGFYHRWFRYS
PCEWRDYLAELNEQGQAYAQFVASTAECCGEGGIKAWDYVRMGFLSRMGVLNNWLSEEESLWIQSRIHLRALRYYSNWRQ
YFAGYTFGRQYWQSPEDDNLPLLREFLARKEYDDSGNDMFYQLFASDDAYYATLPWQPLADYPTCPETLKDMSDL
>SEQF1516_EDU83789.1 glutamate/aspartate ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLIKTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVG
MVFQHFELFPHLSIIENLTLAQVKVLKRDKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF
DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIVEDSPKDAFFDDPKSDRAKDFLAKIL
H
>SEQF1516_EDU83790.1 DnaJ domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNCWKILNIEETTDVDIIRRAYLALLPSFHPETDPQGFKQLRQAYEEALRIAQSPAKSVWQPEEYEVAEHEILLAFRAL
LASDSERFLPSAWQRFIQQLNYCSMNEIDELRWSLCTIAMNTAHLSFECVVLLAERLRWLQEENVGEIDEEELESFLYAI
AKGNVFNFQIILHLPVAVQNDTIDFYQMFARIWSSHPEWLTLYLAQHRAVIIPDDAKLHRNLLRWYSAGRLGIPELLDYA
RSWREAEPDNEDARYYEYAQRVYCGEGESLLAELCDYWHEYPSTQADALMLQWCRQHRVDYYPLVVMMIEARELVNDQGK
PLLYVPGDSARTRFHLYEILSDEKLSALGRSLVEMVLHKGCKPRISLTRDTEHTLWPLYLVAKQLVQASQPTEESLMPIV
SRLDAENRCPLEALIIRRLLIQAANFTEKQTVEPEPQPQPMPVDDGGPGCLGIIKIIFYIFIFAGLIGKILHLFG
>SEQF1516_EDU83791.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIRVVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEM
SLLGDLVICRQMVEKEAQEQGKPLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE
>SEQF1516_EDU83792.1 leucyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWD
AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYD
NTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVNTGFKAVHPLTGEEIPV
WAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIA
DKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPQWAKTTVNG
MPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPA
KQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGAD
TVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQ
TFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDST
LVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG
>SEQF1516_EDU83793.1 inosine-uridine preferring nucleoside hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEKTLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADN
VHGESGLDGPALPEPTFAPQNCTAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWT
PAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAELLDFFLEYHKDEKWGFVGAPLH
DPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVVDYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA
>SEQF1516_EDU83794.1 hypothetical protein ECH7EC4501_6119 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCQSWIGEYCYPDNALMPHPVSVPKYGMYSGTIRRDYLRR
>SEQF1516_EDU83795.1 apolipoprotein N-acyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGLQALTFNRRPLQSAAIGFCWGFGLFGSGINWVYVSIA
TFGGMPGPVNIFLVVLLAAYLSLYTGLFAGVLSRLWPKTTWLRVAIAAPALWQVTEFLRGWVLTGFPWLQFGYSQIDGPL
KGLAPLMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYIRWFTPQPEKTIQVSMVQGDIPQSLKWDEG
QLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEINQQPFLKALDGELRDKGSSLVTGIVDARLNKQNRYDTYNTIITLG
KGAPYSYESADRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPPLSANGIELTAAICYEIILGEQVRDNF
RPDTDYLLTISNDAWFGKSIGPWQHFQMARMRALELARPLLRSTNNGITAVIGPQGEIQAMIPQFTREVLTTNVTPTTGL
TPYARTGNWPLWVLTALFGFAAVLMSLRQRRK
>SEQF1516_EDU83796.1 DnaK family protein HscC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNAELAIGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIISMDENNHILVGKPAVSRRTSHPDKTAALFKRAMGSNT
NWRLGSDTFNAPELSSLVLRSLKEDAEEFLQRPIKDVVISVPAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGL
HTQQNTRSLVFDLGGGTFDVTVLEYATPVIEVHASAGDNFLGGEDFTHMLVDEVLKRADVARTTLNESELAALYACVEAA
KCSNQSPIHIRWQYQDETRECEFYENELEDLWLPLLNRLRVPIEQALRDARLKPSQIDSLVLVGGASQMPLVQRIAVRLF
GKLPYQSYDPSTIVALGAAIQAACRLRSEDIEEVILTDICPYSLGVEVNRQGVSGIFSPIIERNTTVPVSRVETYSTMHP
EQDSITVNVYQGENHKVKNNILVESFDVPLKRTGAYQSIDIRFSYDINGLLEVDVLLEDGSVKSRVINHSPVTLSAQQIE
ESRTRLSALKIYPRDMLINRTFKAKLEELWARALGDEREEIGRVITDFDAALQSNDMARVDEVRRQASVYLAIEIP
>SEQF1516_EDU83797.1 rare lipoprotein B family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPNGPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGAV
SISQDTASVFRNGQTAEYQMVMTVSASVLIPGRDIYPISTKVFRSFFDNPQMALAKDNEQEMIIKEMYDRAAEQLIRKLP
SIRAADIRSDEEQTSTTTDTPATPARVSTTLGN
>SEQF1516_EDU83798.1 PhoH family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIDTREITLEPADNARLLSLCGPFDDNIKQLERRLGIEINRRDNHFKLTGRPICVTAAADILRSLYVDTAPMRGQIQDI
EPEQIHLAIKEARVLEQSAESVPEYGKAVNIKTKRGVIKPRTPNQAQYIANILDHDITFGVGPAGTGKTYLAVAAAVDAL
ERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMLGFEKVEKLIERNVIEVAPLAYMRGRTLNDAFII
LDESQNTTIEQMKMFLTRIGFNSKAVITGDVTQIDLPRNTKSGLRHAIEVLADVEEISFNFFHSEDVVRHPVVARIVNAY
EAWEEAEQKRKAALAAERKREEQEQK
>SEQF1516_EDU83799.1 alpha-ribazole phosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLDDVSFDLVLCSELERAQHTARLVLSDRQLPVHIIPELN
EMFFGDWEMRHHRDLMQEDAENYSAWCNDWQHAIPTNGEGFQAFSQRVERFIARLSEYQHYQNILIVSHQGVLSLLIARL
IGMPAESMWHFRVDQGCWSAIDINQKFATLRVLNSRAIGVENA
>SEQF1516_EDU83800.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKEEQYLLFALSAPMEILNQGCKPAHDSPKMYTGIKEFDLSSSWGINNRDDLIQTIYQMTDDGHANDLAGLYLTWHRSS
PEEWKALIAGGSERGLIYTQFVAQTAMCCGEGGIKAWDYVRMGFLSRVGVLNKWLTEDESLWLQSRVYERAHHYYHSWMH
YFSAYSLGRLYWQSSQCEDNASLREALTLYKYDSAGSRMFEELAAGSDRFYATLPWQPLTVQPECPVTLKDVSDL
>SEQF1516_EDU83801.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKVAQYYRELVASLSERLRNGERDIDALVEQARERVIKTGELTRTEVDELTRAVRRDLEEFAMSYEESLKEESDSVFMR
VIKESLWQELADITDKTQLEWREVFQDLNHHGVYHSGEVVGLGNLVCEKCHFHLPIYTPEVLTLCPKCGHDQFQRRPFEP
>SEQF1516_EDU83802.1 prolipoprotein diacylglyceryl transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRRANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFY
NFPQFMADPLYLFRVWDGGMSFHGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNF
PFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYIRKPRPMGAVSGLFLIGYGAFRI
IVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVIMMVWAYRRSPQQHVS
>SEQF1516_EDU83803.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNREKGVSSLALVLMLLVLGSLLLQGMSQQDRSFASRVSMESQSLRRQAIVQSALAWGKMHSWQTQPAVQCLLYAATGAR
VCLRLLEDNEALLIAGYEGVSLWRTGEVIDGKIVFSPRGWSDFCPLKEGALCQLP
>SEQF1516_EDU83804.1 exodeoxyribonuclease V, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRMSDVAETLDPLRLPFQGERLIEASAGTGKTFTIAALYLRLLLGLGGSAAFPRPLTVEELLVVTFTEAATAELRGRIR
SNIHELRIACLRETTDNPLYERLLEEIDDKAQAAKWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDES
LLRYQACADFWRRHCYPLPREIAQVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETLASRHAQIVARIDTVKQQWR
DAVGELDALIESSGIDRRKFNRSNQAKWIDKISAWAEEERNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLL
AEPLSIRDLVITRALAEIRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQQYRIF
RRIWHHQPETALLLIGDPKQAIYAFRGADIFTYMKARSEVHAHYTLDTNWRSAPGMVNSVNKLFSQTDDAFMFREIPFIP
VKSAGKNQALRFVFKGETQPAMKMWLMEGESCGVGDYQSTMAQVSAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVL
VRSRQEAAQVRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLNALDIETLNNDEHA
WDAVVEEFDGYRQIWRKRGVMPMMRALMSARNIAENLLATAGGERRLTDILHISELLQEAGTQLESEHALVRWLSQHILE
PDSNASSQQMRLESDKHLVQIVTIHKSKGLEYPLVWLPFITNFRVQDQAFYHDRHSFEAVLDLNAAPESVDLAEVERLAE
DLRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQSALGRLLQKGEPQDAAGLRTCIEALCDDDIAWQTAQTGDNQP
WQVNDALTAELNARTLQRLPGDNWRVTSYSGLQQRGHGIAQDLMPRLDVDAAGVVSVVEEPTLTPHQFPRGASPGTFLHS
LFEDLNFTQPVDPNWVQEKLELGGFESQWEPVLTEWITAVLQAPLNETGVSLSQLSDRDKQVEMEFYLPISEPLIASQLD
ALIRQFDPLSAGCPPLEFMQARGMLKGFIDLVFRHEGRYYLLDYKSNWLGEDSSAYTQQAMAAAMQAHRYDLQYQLYTLA
LHRYLRHRIADYDYERHFGGVIYLFLRGVDKEHPQQGIYTTRPNAGLIDLMDEMFAGMTLEEA
>SEQF1516_EDU83805.1 cysteine desulfurase, sulfur acceptor subunit CsdE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNPQFAGHPFGTTVTAETLRNTFAPLTQWEDKYRQLIMLGKQLPALPDELKAQAKEIAGCENRVWLGYTVAENGKMHFF
GDSEGRIVRGLLAVLLTAVEGKTAAELQAQSPLALFDELGLRAQLSASRSQGLNALSEAIIAATKQV
>SEQF1516_EDU83806.1 (Di)nucleoside polyphosphate hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGESAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLP
KRLVRWDTKPVCIGQKQKWFLLQLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQE
NTPKPQNASAYRRKRG
>SEQF1516_EDU83807.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKTAAIISACMLTFALSACSGSNYVMHTNDGRTIVSDGKPQTDNDTGMISYKDANGNKQQINRTDVKEMVELDQ
>SEQF1516_EDU83808.1 cysteine desulfurase, catalytic subunit CsdA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVFNPAQFRAQFPALQDAGVYLDSAATALKPEAVVEATRQFYSLSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPD
DKTIVWTRGTTESINMVAQCYARPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAKVVKLPLNAQRLPDVDLLPELITPR
SRILALGQMSNVTGGCPDLARAITFAHSAGIVVIVDGAQGAVHFPADVQQLDIDFYAFSGHKLYGPTGIGVLYGKSELLE
AMSPWLGGGKMVHEVSFDGFTTQSAPWKLEAGTPNVAGVIGLSAALEWLADYDINQAENWSRSLATLAEDALAKRPGFRS
FRCQDSSLLAFDFAGVHHSDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASFAPYNTKSDVDALVNAVDRALELLV
D
>SEQF1516_EDU83809.1 exodeoxyribonuclease V, gamma subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQWLQMTLSQKFGIAANIDFPLPASFIWDMFVRVLPEI
PKESAFNKQSMSWKLMTLLPQLLEREDFTLLRHYLTDDSDKRKLFQLSSKAADLFDQYLVYRPDWLAQWETGHLVEGLGE
AQAWQAPLWKALVEYTHELGQPRWHRANLYQRFIETLESATTCPPGLPSRVFICGISALPPVYLQALQALGKHIEIHLLF
TNPCRYYWGDIKDPAYLAKLLTRQRRHSFEDHELPLFRDSENAGQLFNSDGEQDVGNPLLASWGKLGRDYIYLLSDLESS
QELDAFVDVTPDNLLHNIQSDILELENRAVAGVNIEEFSRSDNKRPLDPLDSSITFHVCHSPQREVEVLHDRLLAMLEED
PTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAISDRRARQSHPVLEAFISLLSLPDSRFVSEDVLALLDVPVLA
ARFDITEEGLRYLRQWVNESGIRWGIDDDNVRELELPATGQHTWRFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAEL
VGHLASLLMQLNIWRRGLAQERPLEEWLPVCRDMLNALFLPDAETEAAMTLIEQQWQAIIAEGLGAQYGDAVPLSLLRDE
LAQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGMNDGVYPRQLAPLGFDLMSQKPKRGDRSRRDDDRYLFLEAL
ISAQQKLYISYIGRSIQDNSERFPSVLVQELIDYIGQSHYLPGDEALNCDESEARVKAHLTCLHTRMPFDPQNYQPGERQ
SYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRFWAHPVRAFFQMRLQVNFRTEDSEIPDTEPFILEGLSRYQI
NQQLLNALVEQDDAERLFRRFRAAGDLPYGAFGEIFWETQCQEMQQLADRVIACRQPGQSMEIDLACNGVQITGWLPQVQ
PDGLLRWRPSLLSVAQGMQLWLEHLVYCASGGNGESRLFLRKDGEWRFPPLAAEQALHYLSQLIEGYREGMSAPLLVLPE
SGGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMMVSGEGDDIWYQRLWRQLTPETMEAIVEQSQRFLLPLFRFN
QS
>SEQF1516_EDU83810.1 membrane-bound lytic murein transglycosylase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGTVVAMLAACSSKPTDRGQQYKDGKFTQPFSLVNQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRA
GGDTRNMRQFGIDAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGALSDKYILAYS
NSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDRGEVKKEDMSMQAIRHWGETHSEAEVRELLEQN
PSFVFFKPQSFAPVKGASAVPLVGRASVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIY
QGIGPEAGHRAGWYNHYGRVWVLKTAPGAGNVFSG
>SEQF1516_EDU83811.1 exodeoxyribonuclease V, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSHDAGEGHVCLPLSRLENNEESHPLLATCVSEIGELQN
WEECLLASQAVSRGDEPTPMILCGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPTGDEINWQKVAAAV
ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKKRIPEDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAG
FTAERAGQLSRLTGTHVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTDIEKRLLQS
GEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFGVAGLNERIEQFMQQKRKIHRNPHSRWYEGR
PVMIARNDSALGLFNGDIGIALDRGQGTRVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPV
VTRELVYTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE
>SEQF1516_EDU83812.1 prepilin peptidase-dependent protein C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSASLKNQQGFSLPEVMLAMVLMVMIVTALSGFQRTLMNSLTSRNQYQQLWRHGWQQTQLRAISPPANWQVNRMQTSQAG
CVSISVTLVSPGGRAGEMTRLHCPNRQ
>SEQF1516_EDU83813.1 N-acetylmuramoyl-L-alanine amidase AmiC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGSNTAISRRRLLQGAGAMWLLSVSQVSLAAVSQVVAVRVWPASSYTRVTVESNRQLKYKQFALSNPERVVVDIEDVNL
NSVLKGMAAQIRADDPFIKSARVGQFDPQTVRMVFELKQNVKPQLFALAPVAGFKERLVMDLYPANAQDMQDPLLALLED
YNKGDLEKQVPPAQSGPQPGKAGRDRPIVIMLDPGHGGEDSGAVGKYKTREKDVVLQIARRLRSLIEKEGNMKVYMTRNE
DIFIPLQVRVAKAQKQRADLFVSIHADAFTSRQPSGSSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTM
FDMVQSLTIADSLKFGKAVLNKLGKINKLHKNQVEQAGFAVLKAPDIPSILVETAFISNVEEERKLKTATFQQEVAESIL
AGIKAYFADGATLARRG
>SEQF1516_EDU83814.1 thymidylate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIW
DEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIF
DYRFEDFEIEGYDPHPGIKAPVAI
>SEQF1516_EDU83815.1 protease III [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRSTWFKALLLLVALWAPLSQAETGWQPIQETIRKSDKDNRQYQAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDP
EAYQGLAHYLEHMSLMGSKKYPQADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAE
RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQALKDFHEKYYSANLMKAVIYSNKP
LPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKGIIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSP
GTLSDWLQKQGLVEGISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDELANVLDIDF
RYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMTPQNARIWYISPKEPHNKTAYFVDAPYQVDK
ISEQTFADWQQKAANIALSLPELNPYIPDDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFSSEPKADVSLILRNPKAM
DSARNQVMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEGYFSYTATEDQLEQAKSW
YNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSITLKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDV
QKQLGADGSEWCRNKDVVVDKKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLGYA
VFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQAVITQMLQAPQTLGEEALKLSKDF
DRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVVEPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEK
NE
>SEQF1516_EDU83816.1 amino-acid N-acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSSIVNDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEP
LYHKNIRVTDAKTLELVKQAAGTLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEDA
IHRQLDSGAIVLMGPVAVSVTGESFNLTSEEIATQLAIKLKAEKMIGFCSSQGVTNDDGDIVSELFPNEAQARVEAQEEK
GDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGALLQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQG
ILVRRSREQLEMEIDKFTIIQRDNTTIACAALYPFPEEKIGEMACVAVHPDYRSSSRGEVLLERIAAQAKQSGLSKLFVL
TTRSIHWFQERGFTPVDIDLLPESKKQLYNYQRKSKVLMADLG
>SEQF1516_EDU83817.1 phosphoenolpyruvate-protein phosphotransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLADHDRRCYYLMATRGLKKPRGRTVTLAFDEGIVGLVGR
LAEPINLADAQKHPSFKYIPSVKEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQLT
ALFGQYRQTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEEAANEFRRYSKRFAAGAQKETAA
IFDLYSHLLSDTRLRRELFAEVDKGSVAEWAVKTVIEKFAEQFAALSDNYLKERAGDLRALGQRLLFHLDDANQGPNAWP
ERFILVADELSATTLAELPQDRLVGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSVLHRRTLIVDGYRGELLVDPEPV
LLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEKLGSRIDGIGLYRTEIPFMLQSGFPSEEEQV
AQYQGMLQMFNDKPVTLRTLDVGADKQLPYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLNILLPMVT
SLDEVDEARRLIERAGREVEEMIGYEIPKPRIGIMLEVPSMVFMLPHLAKRVDFISVGTNDLTQYILAVDRNNTRVANIY
DSLHPAMLRALAMIAREAEIHGIDLRLCGEMAGDPMCVAILIGLGYRHLSMNGRSVARVKYLLRRIDYAEAENLAQRSLE
AQLATEVRHQVAAFMERRGMGGLIRGGL
>SEQF1516_EDU83818.1 prepilin peptidase dependent protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVKEQGFSLLEVLIAMAISSVLLLGAARFLPALQRESLTSTRKLALEDEIWLRVFTVAKHLQRAGYCHGICTGEGLEIV
GQGDCIIVQWDANSNGIWDREPVKESDQIGFRLKEQVLETLRGATSCEGKGWDKVTNPDAIIIDTFQVVRQDVSGFSPVL
TVNMRAASKSEPQTVVDASYSVTGFNL
>SEQF1516_EDU83819.1 ThiF family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVG
LAKAEVMAERIRQINSECCVTVVDDFVTPDNVAQHMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQIDPT
QIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGTVCAMKATAEGPKRMDCASGFGAAT
MVTATFGFVAVSHALKKMMAKAARQG
>SEQF1516_EDU83820.1 prepilin peptidase-dependent protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTQRGYTLIETLVAMLILVMLSASGLYGWQYWQQSQRLWQTASQARDYLLYLREDANWHNRDHSISFIREGTLWCLVSS
VAGANTCHGSSPLVFVPRWPEVEMSDLTPSLAFFGLRNTAWAGHIGFKNSTGEWWLVVSPWGRLRLCQQGETEGCL
>SEQF1516_EDU83821.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISDKLITLVKSLCVLVGISFLVMLVAIFFSTAWRVLTLSGLVG
>SEQF1516_EDU83822.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKKYELVVKGINNYPDKITVTVALEIGGYPSLLLPDVAISLDRTEGATLEFYEAEAKKQAKQFFMDVAAGLCEGDGPLP
EKRPVILEAQDVLITYRGKLPGIITGSLKTPPLA
>SEQF1516_EDU83823.1 crossover junction endodeoxyribonuclease RusA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIEFVLLYPPTVNTYWRRRGSTYFVSKAGERYRRAVALIVRQQRLKLSLSGRLAIKIIAEPPDKRRRDLDNILKAPLDA
LTHAGLLMDDEQFDEINIVRAQPVSGGRLGVKIYPIMLEGQVKK
>SEQF1516_EDU83824.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVLLRPVLVPELGLVIVKPGRESMSAFHNGRILVEPEPKSMRALPSGVVPAVHQPLAEDKSLLPFFSDERVIRAAGGAG
ALSDWLLRHVKSCQWLHGDYHHSETVIHRYGTGAMVLCWHCDNQLREQTSDSLDQLAQQNLAAWMIDIIRHAMNGAQERE
LSLAELSWWAVRNQVADALPEAVLRRSLGLRAEKIRSVYRESDIIPGEQTATSILKQRTKNIALPSHTHQQQNPPQEKTV
VSIAVDPESPESFRKRPKRRRWVNEKYTRWVKTQPCACCGKPADDPHHLIGHGQGGMGTKSHDIFTLPLCREHHNELHAD
PLAFEEKHGSQVDLIFRFLDHAFATGVLG
>SEQF1516_EDU83825.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIAELTAAMTAIRETAQIAKLMNEAKTQAEVNAAIGELNSKLASIQRECVSLVELVGTYQEINASLKAKIAEFENFEAQT
EGYILSQLESGTFVYSKEVTVNGGSIIMHLCPKCFGQKIVSILQPFPVREYEFFHKSRCLYCENQFLMNKNPDYVSPPSI
EELARKLNGNL
>SEQF1516_EDU83826.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGIPPPDTTFEGNPGTATDTTLFPPQDIYPPGVQSFDSAR
>SEQF1516_EDU83827.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEDPDGDYVLFDDVVKLFEFDTTTQKLEIPAKEAASGQD
>SEQF1516_EDU83828.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDRCRAGETWPPDLAEFVALISESGANPFGLTVDAVMEEYRRWRNESWRYDGSDKYPWPQPVLYHICLEMRDRGIERQMT
EGELKRLAERQLTKWAKQVGNGMSIPPIRRQLASPKCPQGPTPIELLKQEYERRKAAGFV
>SEQF1516_EDU83829.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNGQISIVRPGACDDREIRMIIRLAMGKTITALITPENLALALTGKSDMPVELKLRNVEIKVK
>SEQF1516_EDU83830.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFVQLILLYFCTVVCTLYLVSGGYKVIRNYIRKKIDAAAAEKISASQSAGTKPEEPLIS
>SEQF1516_EDU83831.1 spermidine/putrescine ABC transporter, periplasmic spermidine/putrescine-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKWSRHLLAAGALALGMSAAHADDNNTLYFYNWTEYVPPGLLEQFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLV
VPSTYYVDKMRKEGMIQKIDKSKLTNFSNLDPDMLNKPFDPNNDYSIPYIWGATAIGVNGDAVDPKSVTSWADLWKPEYK
GSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYNELKKLMPNVAAFNSDNPANPYMEGEVNLGMIWNGSAFVARQAG
TPIDVVWPKEGGIFWMDSLAIPANAKNKEGALKLINFLLRPDVAKQVAETIGYPTPNLAARKLLSPEVANDKTLSPDAET
IKNGEWQNDVGAASSIYEEYYQKLKAGR
>SEQF1516_EDU83832.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANAWLRLWHDMPNDPKWRTIARVSGQPIATVMAVYIHLLVSASRNVTKCHGESLRGHIDVTTEDLASALDVTEDVIDSI
LHAMQGRVLDGDLISGWEKRQVMKEDNGNVSQTAKSPAERKRAQRERERLREQNTDCHDESRRVTHMSRQVTTDTDTDKE
LNPTHNARMRESAPASESNGAPLQTAEPEYPDGLSEPIGKFPMTGVWRPSLDFRQRAALWGMALPEPEFTPAELAAFRDY
WMAEGKVFTQVQWEQKFARHVQHVRAQVKPVSKGVSHAAPGGTASRAVQEIRAAREQWERENGFISNGNGLEAVGTYGGG
VFEPLDPEERGCAVEALDCSDWRDD
>SEQF1516_EDU83833.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METVSDALKALKRASSHVVAARLGISREEAVNELWKLKRRGEADNKGAIWWLTQAGESEPVSPVPKVTAQMLTEAIEQHG
PQTADELALMFGITSRRANSSLAMAISKGCLIRVNQDGKFRYCIPGVDLPAEPKAASVAETEGKALPQPAGVALPVQETA
AQEEIKTEAVEDIVKLQQSFTEAKADDLILPSLHVANRELRRAKSNVQKWERVCAALRELNKHRDILRDITATREQQR
>SEQF1516_EDU83834.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGVKTFAGIHTKGGNMSDDISLAMEGALAVIAVVGVYCLVVFLMDRLGN
>SEQF1516_EDU83835.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKHEHIRMAMNAWAYPDGEKVPAAEIARTYFELGMTFPELYDDSHPEALARNTQKIFRWLDKDTPDAVEKMQALLPAI
EKAMPPLLVARMRSHSSEYYREIVERRDRLVKDVDDFVAAAIAWGTLTNSGGQPGNAVVVH
>SEQF1516_EDU83836.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKIDYQALREAAQNYQSTLAWYQATPDSPNAERDCDAALAAFKRHIRHREADIIADLLDGLEEAKSQLNEQREYYEGVI
SDGSKRIAELEAREVQLPTRYDLRYGHPINADERHVMIPKENGSWLYLIDLEHALRVAGIRIKGE
>SEQF1516_EDU83837.1 N-acetylglucosamine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVCELVAEADQRFGCKGSVGIGIPGMPETEDGTLYAANV
PAASGKPLRADLSARLDRDVRLDNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRL
PVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLPAPEIIALYDQGDEQARAHVERYLDLLAVCLGNI
LTIVDPDLVVIGGGLSNFPAITTQLADRLPRHLLPVARVPRIERARHGDAGGMRGAAFLHLTD
>SEQF1516_EDU83838.1 exodeoxyribonuclease VIII [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDEIPLDDALLQLREFIDENSGEFFVQVWGNGANFDNTILRRSYERQGIPCPWRYYNDRDVRTIVELGKAIDFDARTAI
PFEGERHNALDDARYQAKYVSVIWQKLIPSQADF
>SEQF1516_EDU83839.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIDPAITIDMALNAGLALLGYFYIMFCSGRWLSLLFMKKWNKRRKQEQRQKAMDAFFEAFGIDGMEPGDPARAISRGGV
VILVYRSEEKNDDHKTTCRRNHIPH
>SEQF1516_EDU83840.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVESIGYLIGRSESAVRTKARELGISMMLRGDYHQSAKCSQRDIELAWQLHQRGVPRREIAEKFGMKLGAVNNYVYFDR
RVQE
>SEQF1516_EDU83841.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLLVTVKPFQGTIPFRILQRGRVLVEGSFSGKCTQLHSRTFQVNATNEELTVECTMNAAKCRMVSAALQPVC
>SEQF1516_EDU83842.1 spermidine/putrescine ABC transporter, permease protein PotC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTTKWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSL
TAVALYRYRFRGKPFVSGMLFVVMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
AAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPSYEILPLKIYSMVKVGVSPEVNALATILLVL
SLVMVIASQLIARDKTKGNTGDVK
>SEQF1516_EDU83843.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRVLCVVIIVMAVGCGALWLATNHYRDNALTYKAQRDKKARELEQANATITDMQVRQRDVAALDAKYSRELADARAENE
TLRADVAAGRKRLRINATCPGTVREATGTSGVGNDAAVELSPVAGRNVLGIRDGIISDQAALRMLQEYIRTQCIN
>SEQF1516_EDU83844.1 phage integrase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSPRPRKNSTDVAGLYEKFDRRTGRVYYQYKNPVTGKFHGLGTDKGKAEKIASTANQRIAAAEAEYFMRKIDESPSATKR
RGIRLKAWVDRYLKIQDTRLKNGDIAATTHKEKTRMAAYLVSRLGNHPLKELEVRDFALILDEWLDKDMVSTARVNRGLW
VDIYKEAQHAGEVPPGWNPPEATRKPIPKVTRARLTMEDWQKIYNATPEKHFIRNAMLLAIVTGQRRDDICHMRFSDVWN
EHLHITQGKTGMRLALPLTLRCDAIGITLKEVIDGCRDRILSPYLIHSRHQKQPKPMSKDNLSDYFAKARDLAGVIPPAG
KTPPTFHEQRSLSERLYRAQGIDTKTLLGHKVQATTDRYNDTRGQEWVKLVI
>SEQF1516_EDU83845.1 NAD-dependent deacetylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVLVLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEG
FDRDPELVQAFYNARRRQLQQPEIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQ
VLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGHVYPAAGFVHEAKLHGAHTVELN
LEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGL
>SEQF1516_EDU83846.1 putative phage terminase, large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWSTACPDWAERLKKGLSIIPAPIYPEQAAHALAIFKQLRIVDAPGSPTFGESCAQWVFDLVAALFGSYDAQTGVRHIKE
VFILIPKKNSKSTLAAGIMMTALLLNWRQAAGYTILAPTVEVAANAFNPARDMVRRDDDLDDLCQVQTHIRTITHRVTDT
TLKVVAADPNTVSGIKSVGTLIDELWLFGKQYKAEDMLREAIGGLASRPEGFVVYTTTQSNEPPAGVFRQKLQYARDVRD
GKIHDPHFLPVIFEHPPEMVESGAHLLMENLAMVNPNLGYSVDEAFLYREYRKAREAGEEAFRGFMSKHANVEIGLALRS
DRWAGADFWEQQGRRVSLDDILQRADVVTVGIDGGGLDDLLGMYVIGRDRETREWLGWGHAWAHETAVVRRKSEASRFQD
LVACGDMTIVRRVGDDTAEVAEYVRRIHEAELLDHIGIDPSGVGQILDSLAEAGIPDGIVVGISQGWKLGGAIKTTERKL
AEGVLVHGDQPLMAWCVGNARVEPKGNAILITKQASGRGKIDPLMALFNAVSLMSLNPEPKKKEYAVFFI
>SEQF1516_EDU83847.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFMLTVSGVVILSIAYTADKYGCHLLSRIGAYCSLMLIFSSLFFE
>SEQF1516_EDU83848.1 phage lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAKIRYGLSAAVLALIGAGASAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGATRVDGKPVIPGMKLSKEKCDRVNAI
ERDKALAWVEKNIRVPLTEPQKAGIASFCPYNIGPGKCFPSTFYRRINAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
VSRRDQESALACWGIDR
>SEQF1516_EDU83849.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEIKSLVTAEAVKDVLRSEEVRSALKQQLRQNLEARLDAEVDAILDELLGGPAAPEPEDGAGDSAVSDGVVSQPDGSSE
PQPGGEMMM
>SEQF1516_EDU83850.1 HNH endonuclease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDLCDSELDHRIALQFGGGNEETNLWTLCTECHRQKSASEAASGMPDPTLPELPDGTLRADGITGL
>SEQF1516_EDU83851.1 Ant protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMMAVPFHGNSLYVVNHNGEPYVPMKPVVAGMGLAWQSQLAKLRQRFASTITEIVMVAEDGKQRNMVSMPLRKLAGWLQ
TINPNKVKPEIRDKVIRYQEECDDVLYEYWTKGFVVNPRKMSVMEELNQACADMKRDKNIASVFATGLNEWKQVKAAHVS
KIRTLVNEANMLIDFVLADTGKGKITKAD
>SEQF1516_EDU83852.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQMEKITTGVSYTTSAVGTGYWLLQLLDKVSPSQWVAIGVLGSLLFGLLTYLTNLYFKIREDRRKAARGE
>SEQF1516_EDU83853.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAGFNFNYAAGFCSATPALRGYEVSMDTLDLGNNESLVCGVFPNQDGTFTAMTYTKSKTFKTESGARRWLARNSD
>SEQF1516_EDU83854.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSKNRPRRTTIRNIRFPNHMIEQINIALEHKGSGNFSAWVIEACRRRLSTERSGMNYIIK
>SEQF1516_EDU83855.1 YjhS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIKHYDVVRAASPSDLAEKLTHKLKEGWQPFGSPVAITPYTLMQAIAAEGDVTTPVVVPGTGDGGYPGVVTTEPDYYYV
IPLAGQSNGMAYGEGLPLPQTYDRPDPRIKQLARRSTVTPDGAPCKYNDIIPADHCLHDVQDMSRLNHPKADLSKGQYGT
VGQGLHIAKKLLPFIPANAGILLVPCCRGGSAFTTGADGTYSDVTGASESSTRWGVGRPLYKDLIGRTKAALAKNPKNVL
LAVVWMQGEFDFDGTPANHTARFTEVVEQYRTDLADMVGQCAGGSADGVPWICGDTTYFWKQKSESTYQTVYGSYKNKTE
KNIHFVPFMTDENGANVPTNKPEEDPDIPASGYYGAASRTSANWTSADRASHFSSWARRGIISDRLASAILLHAGRTAEL
VGGEQVVMPPDEKPSPDTPSTPSTDGKSVTTLLYYRATESGGLLNPQGWGAEGGRALVVDDAGAAGGKALRWTKQTGSSS
WFMQHDAGNGADLLEKGGLISCRFKVDGTLTANQYALALYWPVSSLPQGVTLEGNAGHNLLASFYVQSDATDLNVMYHKG
NAGQNTKLGSFGAFDNEWHTLGFRFAGNNSIEVTPVIDGKDGTPFMLSQSPVGTFTADKLRVTDITSGATYPVLIESITV
EVNNP
>SEQF1516_EDU83856.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTITKDRLLTIQHWRETYGPGSNVVLPAEEAEELARIALASLAAVSDERAAYELFMEKRFGESVDRRRAKNGDRDYMVW
DMALGWIIWCHRAAMLQAGNFRENKGSSTNNFREISETSTNYPVTPDGWISCSERMPDDGQHVIILCDGAFVLYAQYRDG
EFFDVVRNGDEFFETQSRNVTDWMPLPEPPQEVRQ
>SEQF1516_EDU83857.1 antitermination protein Q [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLEDLPKYYSPKSPGLTDASASTSKDTLSITDVMAAQGMTQNWAEMGFSAFLGKMGISMNDRERATELLTEYALSRCDR
VAALRKLPAEIKPAVMRIMASYAFEDYARSAASKKQCPCCHGKKFIESEVFTNKIQYPDGKPPVWAKCTKGVYPSYWEEW
KKVREVVKVACPECGGKGEVSTACKDFRGRGVAIHREESVKRGMPVIRDCQRCGGRGYERLPSTEAFNAICNVTDAISLD
TWKKTVKRFYDTLVVQFDIEEAWAEQQLKKVTR
>SEQF1516_EDU83858.1 hypothetical protein ECH7EC4501_2253 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSPHGRWSGAMVEEAGCLSLLIDNTEMDSLIFSTFLYSYY
>SEQF1516_EDU83859.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVKLRLAVAALLLFLVVMVDFTSRIMSVLADGGLVCGIVVLLWPVIKRNSLHNA
>SEQF1516_EDU83860.1 Rac prophage repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSGKDLGRAIEQAINKKIASGAVKSKAEIARHFKVQPPSIHDWIKKGSISKDKLPELWRFFSDVVGPEHWGLNEYPIPT
PSTSDTKSELLDINSLYQAASDEKRAIVAFLLSGNATEPSWVDHDVRAYIAAMEMKVANYLKNQESKRKSQNITKTGT
>SEQF1516_EDU83861.1 putative excisionase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEQYLITLDEWKPKRFSLPITNTTLVKYGKLGYIVPRPQKIRGRWLIDRRAVFVGPGETGIAPEIHTGDDDALKEILTH
VTEATKKQH
>SEQF1516_EDU83862.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVYIAGPMTGYENFNREAFHKTEEVLKREGHTVLNPAVLPDGLTQPHYMDICMAMLRCVDAVYMLKGWQQSAGAGAELA
LEEKPGHAVIFQEVGSEY
>SEQF1516_EDU83863.1 regulator of sigma D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKESYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKL
EGNGQLARAAKIWPQLEANTQQIMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKHPA
>SEQF1516_EDU83864.1 thiamine biosynthesis protein ThiS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQILFNDQPMQCAAGQTVHELLEQLVQRQAGAALAINQQIVPREQWTQHIVQDGDQILLFQVIAGG
>SEQF1516_EDU83865.1 thiazole biosynthesis protein ThiG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKRVDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIF
AAHLAREALGTNWLKLEIHPDARWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQG
LETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAKAFRLAVEAGLLAPQSGPGSRSY
FAHATSPLTGFLEASV
>SEQF1516_EDU83866.1 ribosomal protein L7/L12 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAGPVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLG
LKEAKDLVESAPAALKEGVSKDDAEALKKALEEAGAEVEVK
>SEQF1516_EDU83867.1 uroporphyrinogen decarboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAGDFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILT
VPDAMGLGLYFEAGEGPRFTSPVTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGS
SKAFTVIKKMMYADPQALHALLDKLAKSVALYLNAQIKAGAQAVMIFDTWGGVLTGRDYQQFSLYYMHKIVDGLLRENDG
RRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIADARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEG
HVFNLGHGIHQDVPPEHAGVFVEAVHRLSEQYHR
>SEQF1516_EDU83868.1 DNA-directed RNA polymerase, beta' subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETINYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQIL
TEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLTKRIKLLEAFVQSGNKPEWMILT
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLATTIKAAKKM
VEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPIIVPSQDVVLGLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDAN
GELVAKTSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQIMYTGFAYAARSGASVG
IDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKVIDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFN
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADILVPRNTLLHEQWCDLLEENSVDAV
KVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEAIGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKL
SNVKSVVNSSGKLVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITEVSGFVRFTDM
IDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDVLIPGTDMPAQYFLPGKAIVQLEDGVQISSGDT
LARIPQESGGTKDITGGLPRVADLFEARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFE
GERVERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLRKATIVNAGSSDFLEGEQV
EYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFISAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAG
TGYAYHQDRMRRRAAGEAPAAPQVTAEDASASLAELLNAGLGGSDNE
>SEQF1516_EDU83869.1 zinc resistance-associated protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRNTKIALVMMALSAMAMGSTSAFAHGGHGMWQQNAAPLTSEQQTAWQKIHNDFYAQSSALQQQLVTKRYEYNALLAAN
PPDSSKINAVAKEMENLRQSLDELRVKRDIAMAEAGIPRGAGMGMGYGGCGGGGHMGMGHW
>SEQF1516_EDU83870.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQNPIHLRLERLESWQHVTFMACLCERMYPNYAMFCQQTGFGDGQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIP
SADDFDLYGVYPAIDACVALSELVHSRLSGETLEHAVEVSKTSITTVAMLEMTQAGREMSDEELKENPAVEQEWDIQWEI
FRLLAECEERDIELIKGLRADLREADESNIGIIFQQ
>SEQF1516_EDU83871.1 DNA-binding protein HU-alpha [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQLVGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFV
SGKALKDAVK
>SEQF1516_EDU83872.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAGALFLTACSHNSSLPPFTASGFAEDQGAVRIWRKDSGDNVHFLAVFSPWRSGDTTTREYRWQGDNLTLININVYSKP
PVNIRARFDDRGDLSFMQRESDGEKQQLSNDQIDLYRYRADQIRQISDALRQGRVVLRQGRWHAMEQTVTTCEGQTIKPD
LDSQAIAHIERRQSRSSVDVSVAWLEAPEGSQLLLVANSDFCRWQPNEKTF
>SEQF1516_EDU83873.1 hypothetical protein ECH7EC4501_5641 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRYPQQASHFYSFIMPDYPSYQRFIVGTEDAIPEVRQPLED
>SEQF1516_EDU83874.1 thiazole biosynthesis adenylyltransferase ThiF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDID
RPKSQVSHQRLTQLNPDIQLTALQQRLTGEALKDAVAQADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMV
LTPPWGQGCYRCLWPENQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGELRLFDGKSSQWRSLALRRASGC
PVCGGSNADPV
>SEQF1516_EDU83875.1 thiazole biosynthesis protein ThiH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTFSDRWRQLDWDDIRLRINGKTAADVERALNASQLTRDDMMALLSPAASGYLEQLAQRAQRLTRQRFGNTVSFYVPLY
LSNLCANDCTYCGFSMSNRIKRKTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQ
PLAETEYAELKQLGLDGVMVYQETYHEATYARHHLKGKKQDFFWRLETPDRLGRAGIDKIGLGALIGLSDSWRVDCYMVA
EHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMDERQLVQTICAFRLLAPEIELSLSTRESPWFRDRVIPLAINNVSA
FSKTQPGGYADNHPELEQFSPHDERRPEAVAAALTAQGLQPVWKDWDSYLGRASQRL
>SEQF1516_EDU83876.1 endonuclease V [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEVTRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSF
REYPALLAAWEMLSQKPDLVFVDGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLA
WVWRSKARCNPLFIATGHRVSVDSALAWVQRCMKGYRLPEPTRWADAVASERPAFVRYTANQP
>SEQF1516_EDU83877.1 phosphoribosylamine--glycine ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPTLQNVAIGVTDIPALLDFAQNEKVDLTIVGPEAPLVKGV
VDTFRAAGMKIFGPTAGAAQLEGSKAFTKDFLARHNIPTAEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMT
LEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRVGDKDTGPNTGGMGAYSPAPVVT
DDVHQRTMERIIWPTVKGMASEGNTYTGFLYAGLMIDKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVELCLAACEGKLD
EKTSEWDERASLGVVMAAGGYPGDYRTGDVIHGLPLEEVEDGKVFHAGTKLADDEQVVTSGGRVLCVTALGHTVAEAQKR
AYALMTDIHWDDCFCRKDIGWRAIEREQN
>SEQF1516_EDU83878.1 thiamine-phosphate pyrophosphorylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQPDFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDRRDEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQA
YGVHLGQEDLQATDLNAIRAAGLRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLSDYP
TVAIGGISLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE
>SEQF1516_EDU83879.1 thiamine biosynthesis protein ThiC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSATKLTRREQRAQAQHFIDTLEGTAFPNSKRIYITGTQPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPY
GDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITP
EMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGIADMSENFRARGGEIYLRKEEA
>SEQF1516_EDU83880.1 response regulator ZraR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQVRERVFDLVLCDVRMAEMDGIATLKEIKALNPAIPV
LIMTAYSSVETAVEALKTGALDYLIKPLDFDNLQATLEKALAHTHIIDAETPAVTASQFGMVGKSPAMQHLLSEIALVAP
SEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHEKGAFTGADKRREGRFVEADGGTLFLD
EIGDISPMMLVRLLRAIQEREVQRVGSNQTISVDVRLIAATHRDLAAEVNAGRFRQDLYYRLNVVAIEVPSLRQRREDIP
LLAGHFLQRFAERNRKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISERELPLAIASTPIPLAQSLDIQ
PLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR
>SEQF1516_EDU83881.1 ribosomal protein L10 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKAGREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPT
LIAYSMEHPGAAARLFKEFAKANAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRD
AKEAA
>SEQF1516_EDU83882.1 sensor histidine kinase ZraS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRETAAARQTLLEKGSVLIRALESGSRVGMGMRMHHAQQQAL
LEEMAGQPGVRWFAVTDEQGTIVMHSNSGMVGKQLYSPQEMQQLHPGDEEVWRRIDSADGEPVLEIYRQFQPMFAAGMHR
MRHMQQYAATPQAIFIAFDASNIVSAEDREQRNTLIILFALATVLLASVLSFFWYRRYLRSRQLLQDEMKRKEKLVALGH
LAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQL
VSQDANCREIQLRFTANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEA
IFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASLEGKGARFTLWLPVNITRKDPQG
>SEQF1516_EDU83883.1 DNA-directed RNA polymerase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPEGQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVF
DVQECQIRGVTYSAPLRVKLRLVIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTEQILDLFFEKVIFEIRDNKLQME
LVPERLRGETASFDIEANGKVYVEKGRRITARHIRQLEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLD
LLAKLSQSGHKRIETLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSEDRYDLSAV
GRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVKERLS
LGDLDTLMPQDMINAKPISAAVKEFFGSSQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCP
IETPEGPNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLDEEGHFVEDLVTCRSKG
ESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMGANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKR
GGVVQYVDASRIVIKVNEDEMYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQNM
RVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPNVGEAALSKLDESGIVYIGAEVTGG
DILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDL
SEELQILEAGLFSRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLEAKRRKITQGD
DLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYDENGTPVDIVLNPLGVPSRMNIGQILETHLGMA
AKGIGDKINAMLKQQQEVAKLREFIQRAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLK
LGDLPTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEA
YGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMPESFNVLLKEIRSLGINIELEDE
>SEQF1516_EDU83884.1 NADH pyrophosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRALQIGEWQGEPVWLIQQQRRYDMGSVRQVIDLDVGLFQ
LAGRGVQLAEFYRSHKYCGYCGHEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGF
VEVGETLEQAVAREVMEESGIKVKHLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPKELLEANWYRYDDLPLLPPPGTV
ARRLIEDTVAMCRAEYE
>SEQF1516_EDU83885.1 outer membrane protein W [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWYMDIDTTAKYKSGVTTVKDSVRLDPWVFMFSAGYRF
>SEQF1516_EDU83886.1 hypothetical protein ECH7EC4501_3829 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALIRLAGYPAGISLFRYSDTLFNGRHSPEIFCSSLA
>SEQF1516_EDU83887.1 enterobacterial Ail/Lom family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKLCAVILSAVVWQVAAATPASAAEHQSTLSAGYLHASTNVPGSDDLNGINVKYRYEFMDALGLITSFSYANAEDEQKT
RYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRVSTFYGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
GAGVQFNPTESVTIDLAYEGSGSGDWRSDAFIVGIGYRF
>SEQF1516_EDU83888.1 phage minor tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEIKTLHLVPREGMQVSEKPSVVRVRFGDGYEQRRPTGLNPQLKTFQAVFRVTDESTRRWLDEFLSWHGGYRAFLWRPP
KHNRTVRVVCREWSVTDNARYSDFSCTIEQVVN
>SEQF1516_EDU83889.1 IS66 family element, orf1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLDAAAEQPESLAEDPETLSISCEVTFRHGTLRFNGNVSEKLLTLLIQELKR
>SEQF1516_EDU83890.1 tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVKISGVLKDGTGKPVQNCTIVLKARRTSSTVVVNTVASENPDEAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYED
SQPGTLNDFLGAMSEDDVRPEALRRFELMVEEAARHAEEAKKNAGEAETSARNAGISASQAEENAANADTSAGDASESAR
QAAESAAAAKQSEEASSSSASAAAQKASESLQSATDAELSKKTAESAAGNAARDATTAAEKARESAESAQSAEQSRIAAE
EAVNRIPTVVGPPGPKGEPGPAGPQGPKGDKGERGDTGPAGATGERGPAGDAGPAGPQGPKGDRGERGETGLTGNAGPQG
PKGDTGAAGPAGPQGPKGETGAAGPVGATGPQGPKGDPGETQIRFRLGPASIIETNSHGWFPGTDGALITGLTFLAPKDT
TRVQGFFQHLQVRFGDGPWQDVKGLDEVGSDTGRTGE
>SEQF1516_EDU83891.1 IpgB2, probably secreted by the Mxi-Spa secretion machinery [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVNATGVSFSSFGISYHKDNSFRGTIRGKNDEVVKCSMGERSIRFNVNKFSGCILETVSRQSTKDIHGWVSDERTVYPS
RVINQEIDNCCLQKNAKISSEERKMVFSLVSKEFELTLDVKAAQSSINHIIIGNASFGKKMDALCDGMSRAVKNSTTDYI
ANVLADKFYQKHIAPGVDIVKLRNEIPGYMSRVIQG
>SEQF1516_EDU83892.1 NleA11 protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIQPTIQSGITSQNNQHHQTEQIPSTQIPQSELPLGCQAGFVVNIPDDIQQHAPECGETTALLSLIKDKGLLSGLDEYI
APHLEEGSIGKKTLDMFGLFNVTQMALEIPSSVSGISGKYGVQLNIVKPDIHPTSGNYFLQIFPLHDEIGFNFKDLPGPL
KNALSNSNISTTAVSTIASTGTSATTSTVTTEPKDPIPWFGLTAQVVRNHGVELPIVKTENGWKLVGETPLTPDGPKANY
TEEWVIRPGEADFKYGASPLQATLGLEFGAHFKWDLDNPNTKYAVLTNAAANALGALGGFAVSRFASTDPMLSPHIGAMV
GQAAGHAIQYNTPGLKPDTILWWAGATLGAADLNKAEFEVARFTDYPRIWWHAREGAIFPNKADIEHATGADIRAMEEGI
PVGQRHPNPEDVVIDIESNGLPHHNPSNHVDIFDIIQETRV
>SEQF1516_EDU83893.1 IS66 family element, transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQLDKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTL
TGRVYDPAVQRPLRQTRTRKPFPESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
DAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELRRSLLSGWVDACCRLLSPLEEALHGYVMT
DGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNAGSALAPAVWFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELY
RNGGITEAACWAHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWLREKMKT
LSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKNFLFFGSDHGGERGALLYSLIGTCKLNDVDP
ESYLRHVLGVIADWPVNRVSELLPWRIALPAE
>SEQF1516_EDU83894.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADSVENQLNGGNSFLDVFSTYMGQVISEFMHSNDNRIELLQRRLHSCSFLVNIEEMSYIDEALQCPITLAIPQRGVFLR
NAEGSRVCSLYDEMALSRIINDGMHHPLSREPITLSMLVAREQCEFDCSIGHFTVRSDCYSV
>SEQF1516_EDU83895.1 hypothetical protein ECH7EC4501_3847 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHLHKDAFKSSETCQPQTPSYILDVCGVFLQITDSQYSLREKYFNYLL
>SEQF1516_EDU83896.1 non-LEE-encoded type III effector H [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSPSSINLGCSWNSLTRNLTSPDNRVLSSVRDAAVHSDSGTQVTVGNRTYRVVVTDNKFCVTRESHSGCFTNLLHRLGW
PKGEISRKIEAMLNTSPVSTTIERGSVHSNRPDLPPVDYAQPELPPADYTQSELPRVSNNKSPVPGNVIGKGGNAVVYED
MEDTTKVLKMFTISQSHEEVTSEVRCFNQYYGSGSAEKIYNDNGNVIGIRMNKINGESLLDIPSLPAQAEQAIYDMFDRL
EKKGILFVDTTETNVLYDRMRNEFNPIDISSYNVSDISWSEHQVMQSYHGGKLDLISVVLSKI
>SEQF1516_EDU83897.1 phage minor tail protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDIHEESLNESVKSEQSPRVVLWEIDLTVQGGERYFFCNELNEKGEAVTWQGREYQAYPIDGSGFEMNGKGSSARPSLT
VSNLFGLVTGMAEDLQSLVGATVVRRRVYARFLDAVNFVAGGRGYRAAEVKRIKKSRRVAGTDKD
>SEQF1516_EDU83898.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLHHISFMDSFSVEPVSGGLLDRLSARGHRLLAENLEIQLNRGHTFLQAFRLYMEQSRATPCTRQNVSSAIQNKINSHA
FTVSHQDFSCHEQHLNCPITLCIPETGVFVRNAKNSEICSLYDHNALTELIRRNAPHPLSREPFVPEMIVSKDECHFNLI
EQYFCILATQNICTRI
>SEQF1516_EDU83899.1 IS66 family element, orf2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPS
ARDGKVFLTQAQLAMLLEGIDWRQPKRLLTSLTML
>SEQF1516_EDU83900.1 putative prophage tail fibre C-terminus family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNILKKLMQRLCGHGKHDDREDGELLTAQLRLGPADILESDENGIIPEQDRVITQVVILDADKKQIQCVVRPLQILRADG
TWENIGGMK
>SEQF1516_EDU83901.1 site-specific recombinase, phage integrase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARPRKYKTDVPGLSPYFDKRNNKVYWRYRHPITGKNHGLGSIDQKLAETIAAEANSRLARQQMEQMLSLQEKIISDTGG
SSTVTIFLNNYRKIQQERYENGEIKLNTLKQKAAPLRVFDERFGTRPLDAITVKDVVSVLEEYKARGHNRMGQIFRKVLI
DVFREAQQTGDVPPGFNPAESAKKPQVRISRQRLTFDEWMMIYNAAEKDGYFLQRGMLLALMTGQRLSDICKMQFSDIRD
GYLHVEQQKTGTRIAIPLALRCDKLNLTLDDVVSSCRDCVLSPWLLHHHHAKGTAKRGGMVKPATLTVAFKKARDSVDYN
WRANGTPPSFHEQRSLSERLFREQGVDTKILLGHSNQKMIDIYNDARGKEWKKLVI
>SEQF1516_EDU83902.1 glucarate dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIKDNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEY
KNVLTLVRNTFADRDAGGRGLQTFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKAT
PLPYQSQPDDSCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAESIVALAQRFPQARITLDPNGAW
SLNEAIKIGKYLKGSLAYAEDPCGAEQGFSGREVMAEFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQ
GSVRVAQMCHEFGLTWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGLVQVPEKPGLGV
EIDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR
>SEQF1516_EDU83903.1 L-fuculose phosphate aldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MERNKLARQIIDTCLEMTRLGLNQGTAGNVSVRYQDGMLITPTGIPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAA
YQSRPDANAVVHNHAVHCTAVSILNRPIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIAC
EVNLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTYGLRIEE
>SEQF1516_EDU83904.1 23S rRNA (uracil-5-)-methyltransferase RumA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGLLPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPR
CPHFGVCGGCQQQHASVDLQQRSKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVK
QCPILVPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREKLERFSHSEGLDLYLAPDSEILE
TVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVARALEWLEVEPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPAL
VEKGQQNARLNCLQNVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPATLARDSEA
LLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK
>SEQF1516_EDU83905.1 L-fucose:H+ symporter permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNLNDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIP
AGILMKKLSYKAGIITGLFLYALGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQT
FNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAIVLLVALLIMLTKFPALQSDNHS
DAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTACWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLIS
RFAPHKVLAAYALIAMALCLISAFAGSHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTIIGGGIVTPV
MGFVSDAAGNIPTAELIPALCFAVIFIFARFRSQTATN
>SEQF1516_EDU83906.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTHDRVRLQLQALEALLREHQHWRNDEPQPHQFNSTQPFFMDTMEPLEWLQWVLIPRMHDLLNNNQPLPGAFAVAPYYE
MALATDHPQRALILAELEKLDALFADDAS
>SEQF1516_EDU83907.1 hypothetical protein ECH7EC4501_4615 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALALDGGIHFTEMKTRTRKEGLKRRNKEEYEMDRLTPGKRQ
>SEQF1516_EDU83908.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNSGSLTDNSKELLSRFENFDINVLRRERGVKLELINPP
EEAFVDGRIIRALQANLFAVLRDILFVYGQIHNTVRFPNLNLDNSVHITNLVFSILRNARALHVGEAPNMVVCWGGHSIN
ENEYLYARRVGNQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPSIIAAEPPNPLVNELIIMPDIEK
RLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPANKDQVLPLILTGPKESADYFRVLDEFVVHTLGENARRHYRIIID
DAAEVARQMKKSMPLVKENRRDTGDAYSFNWSMRIAPDLQMPFEPSHENMANLKLYPDQPVEVLAADLRRAFSGIVAGNV
KEVGIRAIEEFGPYKINGDKEIMRRMDDLLQGFVAQHRMKLPGSAYIPCYEICT
>SEQF1516_EDU83909.1 serine transporter family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METTQTSTIASKDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPINAGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKN
PGEDITEVVEEHFGIGAGKLITLLYFFAIYPILLVYSVAITNTVESFMSHQLGMTPPPRAILSLILIVGMMTIVRFGEQM
IVKAMSILVFPFVGVLMLLALYLIPQWNGAALETLSLDTASATGNGLWMTLWLAIPVMVFSFNHSPIISSFAVAKREEYG
DMAEQKCSKILAFAHIMMVLTVMFFVFSCVLSLTPADLAAAKEQNISILSYLANHFNAPVIAWMAPIIAIIAITKSFLGH
YLGAREGFNGMVIKSLRGKGKSIEINKLNRITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMYAIQKVPAM
RKYSGHISNVFVVVMGLIAISAIFYSLFS
>SEQF1516_EDU83910.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLTTLTRQISSQLICHTIYIATQTFPYFHKPYFIAMKKKLSP
>SEQF1516_EDU83911.1 L-fucose isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEKLRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNV
GLTITVTPCWCYGSETIDMDPTRPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLL
RFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRIDQKIYDEAELEMALAWADKNFRY
GEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQGNSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILN
SSFDWNGVREPFVVATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLINSGSAALDG
SCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRFLTEGGVPFTMTRVNIIKGLGPVLQIAEGWS
VELPKDVHDILNKRTNSTWPTTWFAPRLTGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVKETK
VYRPSAWAAHGMDIEGQDYRACQNYGPLYKR
>SEQF1516_EDU83912.1 fucose operon protein FucU [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIRADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDT
LDPEVERRYRNALSLQAPCPDIIRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP
>SEQF1516_EDU83913.1 lactaldehyde reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQCGVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEG
LGVFQNSGADYLIAIGGGSPQDTCKAIGIISNNPEFADVRSLEGLSPTNKPSVPILAIPTTAGTAAEVTINYVITDEEKR
RKFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHAIEGYITRGAWALTDALHIKAIEIIAGALRGSVAGDKDAG
EEMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPHGVANAILLPHVMRYNADFTGEKYRDIARVMGVKVEGMSLEEAR
NAAVEAVFALNRDVGIPPHLRDVGVRKEDIPALAQAALDDVCTGGNPREATLEDIVELYHTAW
>SEQF1516_EDU83914.1 L-fuculokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSGYIAGAIMKQEVILVLDCGATNVRAIAVNRQGKIVARTSTPNASDIAMENNTWHQWSLDAILQRFADCCRQINSELT
ECHIRGIAVTTFGVDGALVDKQGNLLYPIISWKCPRTAAVMDNIERLISAQRLQAISGVGAFSFNTLYKLVWLKENHPQL
LERAHAWLFISSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIGTLQNSAAAMLGL
PVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDTSLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEW
VRKLFWTAETPWQMLIEEARLIAPGADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHF
KASELLLVGGGSRNTLWNQIKANMLDIPLKVLDDAETTVAGAALFGWYGVGEFNSPEEARAQIHYQFRYFYPQTEPEFIE
EV
>SEQF1516_EDU83915.1 syd protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIISTTEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTF
YTTQFAGDMHAQFGDIKLTLLQTWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGT
RKRTHLAPNLAEFLNQLKPLL
>SEQF1516_EDU83916.1 hypothetical protein ECH7EC4501_4614 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKSGLIERINVVLLHGEPLWRAFYTAIARYKHAPYSANDL
>SEQF1516_EDU83917.1 sensor histidine kinase/response regulator BarA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDAGASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHS
DIVRAISVYDENNRLFVTSNFHLDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYI
ALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGFMLGELDMLKNGI
NSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQNVELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLK
TELTPTQRDHLNTIERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTLNIKSDVPD
NVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIRDTGIGIPERDQSRLFQAFRQADASISRRHG
GTGLGLVITQKLVNEMGGDISFHSQPNRGSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETP
LEVVYSPTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKLKQDGIGACLLKPLTPT
RLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKLIGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQ
MPDMDGIRACELIHQLPHQQQTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPEVN
EIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGLVDLIHKLHGSCGYSGVPRMKNLCQ
LIEQQLRSGTKEEDLEPELLELLDEMDNVAREASKILG
>SEQF1516_EDU83918.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIYECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHL
PPEDRITPIVGMLQGVVEKGGELRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYT
GYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDLGACPGGWTYQLVKRNMWVYSVD
NGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVCDMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNL
AYIQAQLDEHGINAQIQARQLYHDREEVTVHVRRIWAAVGGRRDER
>SEQF1516_EDU83919.1 L-fucose operon activator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQTQGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHK
ADIAREALAWIEEGMVIALDASSTCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEARIGHLDEVTHIISDERQVATSL
VTG
>SEQF1516_EDU83920.1 exodeoxyribonuclease-9 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTHAVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDE
MPALRAAFEQRGVPCWSTSGNEADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGV
QPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKLETHKEMAFLCRDIARLQTDLHI
DGNLQQLRLVR
>SEQF1516_EDU83921.1 tRNA pseudouridine synthase C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIGQHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQH
QIQKRYHAIVRGWLMEEAVLDYPLVEELDKIADKFAREDKGPQPAVTHYRGLATVEMPVATGRYPTTRYGLVELEPKTGR
KHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLTIHAGLDDTWMQALSQFGWRGLL
PENERVEFSAPSGQDGERSS
>SEQF1516_EDU83922.1 L-serine ammonia-lyase 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTRVVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDI
DSIPGFIQDVNTHGRLMLANGQHEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQ
DSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMCGGIERGISTEGVLPGKLRVPRRA
AALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENAAGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVAS
AIGSLYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPCIERNAIAA
VKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMKIVACD
>SEQF1516_EDU83923.1 glucarate permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGSEMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLD
RFGSKRVYFWSIFIWSMFTLLQGFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQY
FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIAISFIWLKVIHEPNQHPGVNQKELEYIAAGGALINMDQQNTKVKVPFSV
KWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTG
SLNIARKTPIVMGMLLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMFGNISGIVT
PIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVVGQ
>SEQF1516_EDU83924.1 flavodoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEIGIFVGTMYGNSLLVAEEAEAILTAQGHKATVFEDPELSDWLPYQDKYVLVVTSTTGQGDLPDSIVPLFQGIKDSLG
FQPNLRYGVIALGDSSYVNFCNGGKQFDALLQEQSAQRVGEMLLIDASENPEPETESNPWVEQWGTLLS
>SEQF1516_EDU83925.1 negative regulator of flagellin synthesis FlgM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIDRTSPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLSDAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTG
KIADALINEAQQDLQSN
>SEQF1516_EDU83926.1 YceI protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLGYSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSV
DTNHAERDKHLRSADFLNTAKYPQATFTSTSVKKDGDELDITGDLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGK
IKLKDFNIKTDLGPASQEVDLIISVEGVQQK
>SEQF1516_EDU83927.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRLLHYLINNIREHLMLYLFLWGLLAIMDLIYVFYF
>SEQF1516_EDU83928.1 flagellar basal-body rod protein FlgC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALLNIFDIAGSALTAQSQRLNVAASNLANADSVTGPDGQPYRAKQVVFQVNAAPGAATGGVKVADVIESQAPDKLVYEP
GNPLADAKGYVKMPNVDVVGEMVNTMSASRSYQANVEVLNTVKSMMLKTLTLGQ
>SEQF1516_EDU83929.1 N-methyl-L-tryptophan oxidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHHGDTRLIRHAYGEGEKYVPLVLRAQTLWDDLSRHNED
DPIFVRSGVINLGPADSAFLANVAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAK
EAGCAQLFNCPVTAIRHDDDGVTIETADGEYQAKKAIVCAGTWVKDLLPELPVQPVRKVFAWYQADGRYSVKNKFPAFTG
ELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERVPFAEVVSDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFII
DTLPGHDNTLLITGLSGHGFKFASVLGEIAADFAQDKKSDFDLTPFSLSRFQ
>SEQF1516_EDU83930.1 glutaredoxin, GrxB family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLYIYDHCPYCLKARMIFGLKNIPVELHVLLNDDAETPTRMVGQKQVPILQKDDSRYMPESMDIVHYVDKLDGKPLLTG
KRSPAIEEWLRKVNGYANKLLLPRFAKSAFDEFSTPAARKYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVK
PNAVNGELSEDDIQLFPLLRNLTLVAGINWPSRVADYRDNMAKQTQINLLSSMAI
>SEQF1516_EDU83931.1 ribosomal-protein-alanine acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFGYRSNVPKVRLTTDRLVVRLVHDRDAWRLADYYAENRHFLKPWEPVRDESHCYPSGWQARLGMINEFHKQGSAFYFGL
FDPDEKEIIGVANFSNVVRGSFHACYLGYSIGQKWQGKGLMFEALTAAIRYMQRTQHIHRIMANYMPHNKRSGDLLARLG
FEKEGYAKDYLLIDGQWRDHVLTALTTPDWTPGR
>SEQF1516_EDU83932.1 oxidoreductase family, NAD-binding [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLRIGVVGLGGIAQKAWLPVLAAASDWTLQGAWSPTRAKALPICESWRIPYADSLSSLAASCDAVFVHSSTASHFDVV
STLLNAGVHVCVDKPLAENLRDAERLVELAARKKLTLMVGFNRRFAPLYCELKTQLATAASLRMDKHRSNSVGPHDLYFT
LLDDYLHVVDTALWLSGGKASLDGGTLLTNDAGEMLFAEHHFSAGPLQITTCMHRRAGSQRETVQAVTDGALIDITEMRE
WREERGQGVVNKPIPGWQSTLEQRGFVGCARHFIECVQNQTVPQTAGEQAVLAQRIVDKIWRDAMSE
>SEQF1516_EDU83933.1 flagellar rod assembly protein/muramidase FlgJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISDSKLLASAAWDAQSLNELKAKASEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDGLFSSEHTRLYTSMYDQQIAQ
QMTTGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPA
QLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL
EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDKVSKTYSMNIDNLF
>SEQF1516_EDU83934.1 lipid A biosynthesis lauroyl acyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNLPKFSTALLHPRYWLTWLGIGVLWLVVQLPYPVIYRLGCGLGKLALRFMKRRAKIVHRNLELCFPEMSEQERRKMVV
KNFESVGMGLMETGMAWFWPDRRIARWTEVIGMEHIRDVQAQKRGILLVGIHFLTLELGARQFGMQEPGIGVYRPNDNPL
IDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGEVVWYAPDHDYGPRSSVFVPLFAVEQAATTTGTWMLARMSGACLVPFV
PRRKPDGKGYQLIMLPPECSPPLDDAETTAAWMNKVVEKCIMMAPEQYMWLHRRFKTRPEGVPSRY
>SEQF1516_EDU83935.1 dihydroorotase, homodimeric type [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMPNLAPPVTTVEAAVAYRQRILHAVPAGHDFTPLMTCY
LTDSLDPNELERGFNEGVFTAAKLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIES
VMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRPHLYCLPILKRNIHQQALRELVA
SGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTALGSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEH
QVAESIALTDDTLVPFLAGETVRWSVKQ
>SEQF1516_EDU83936.1 flagellar hook protein FlgE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFAGSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQN
GFFRLVDSNGSVFYSRNGQFKLDENRNQVNMQGLQLTGYPATGTPPTIQQGANPTNISIPNTLMAAKTTTTASMQINLNS
SDPLPSVNAFDASNADSYNKKGSVTVFDSQGNAHDMSVYFVKTGDNNWQVYTQDSSDPTGTAEPAMKLVFNANGVLTSNP
TENITTGAINGAEPATFSLSFLNSMQQNTGANNIVATTQNGYKPGDLVSYQINDDGTVVGNYSNEQTQLLGQIVLANFAN
NEGLASEGDNVWSATQSSGVALLGTAGTGNFGTLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQILNTLVNL
R
>SEQF1516_EDU83937.1 flagellar P-ring protein FlgI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQ
LKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQL
NGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDARTIQVRVPSGNSSQVRFLADIQ
NMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAIAQGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQ
SVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLRAKLEII
>SEQF1516_EDU83938.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKFLFAAALIVSGLLVGCNQLTQYTITEQEINQSLAKHNNFSKDIGLPGVADAHIVLTNLTSQIGREEPNKVALTGDAN
LDMNSLFGSQKATMKLKLKALPVFDKEKGAIFLKEMEVVDATVQPEKMQTVMQTLLPYLNQALRNYFNQQPAYVLREDGS
QGEAMAKKLAKGIEVKPGEIVIPFTD
>SEQF1516_EDU83939.1 flagellar basal-body rod protein FlgG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERL
HSQGNLSQTNNSKDVAIKGQGFFQVMLPDGSSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVT
QQGQAAPVQVGQLNLTTFMNDTGLESIGENLYTETQSSGAPNESTPGLNGAGLLYQGYVETSNVNVAEELVNMIQVQRAY
EINSKAVSTTDQMLQKLTQL
>SEQF1516_EDU83940.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNREPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTK
YEQRFCNSEFGDLKLSAAEVALITTLLLRGAQTPGELRSRAARMYEFSDMAEVELTLEQLANREDGPFVVRLAREPGKRE
SRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD
>SEQF1516_EDU83941.1 DNA-damage-inducible protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRYAAANNLSVIGATKEDKQRISEILQETWESADDWFVS
E
>SEQF1516_EDU83942.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNKSEQEGTEVGQTLWLTTDVARQFISILEAGIAKIESGDFPVN
EYRRH
>SEQF1516_EDU83943.1 flagellar hook-associated protein FlgK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAAQT
QSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNI
AIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGST
ARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNSQHKAGFDAN
GDEGEDFFAIGKPAVLQNTKNNGNVAIGATVTDASAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELT
FTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIG
NKTATLKTSSTTQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR
>SEQF1516_EDU83944.1 flagella synthesis protein FlgN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRLAEILDQMSAVLNDLKTVMDQEQQHLSMGQINGSQLQWITEQKSSLLATLDYLEQLRRKEPNTANSVDISQRWQEIA
VKTQQLRQMNQHNGWLLEGQIERNQQALEMLKPHQEPTLYGANGQTSTTHRGSKKISI
>SEQF1516_EDU83945.1 flagellar hook capping protein FlgD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIAVTTTDPTNTGVSTTSSSSLTGSNAADLQSSFLTLLVAQLKNQDPTNPMENNELTSQLAQISTVSGIEKLNTTLGSI
SGQIDNSQSLQASNLIGHGVMIPGTTVLAGTGSEEGAVTTTTPFGVELQQAADKVTATITDKNGAVVRTIDIGELTAGVH
SFTWDGTLTDGSTAPNGSYNVAISASNGGTQLVAQPLQFALVQGVIRGNNGNTLDLGTYGTTTLDEVRQII
>SEQF1516_EDU83946.1 flagellar L-ring protein FlgH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTI
VLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGN
LHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM
>SEQF1516_EDU83947.1 integral membrane protein MviN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEDAT
RVFVSYVSGLLTLALAVVTVAGMLAAPWVIMVTAPGFADTADKFALTSQLLKITFPYILLISLASLVGAILNTWNRFSIP
AFAPTLLNISMIGFALFAAPYFNPPVLALAWAVTVGGVLQLVYQLPHLKKIGMLVLPRINFHDAGAMRVVKQMGPAILGV
SVSQISLIINTIFASFLASGSVSWMYYADRLMEFPSGVLGVALGTILLPSLSKSFASGNHDEYNRLMDWGLRLCFLLALP
SAVALGILSGPLTVSLFQYGKFTAFDALMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLILTQLMNLA
FIGPLKHAGLSLSIGLAACLNASLLYWQLRKQKIFTPQPGWMAFLLRLVVAVLVMSGVLLGMLHIMPEWSLGTMPWRLLR
LMAVVLAGIAAYFAALAVLGFKVKEFARRTV
>SEQF1516_EDU83948.1 multidrug resistance protein MdtH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWAAVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIV
TGMLMRAAGFATMGIAHEPWLLWFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQ
YDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLAGYYMLAVQVMLMLPIMVNDVAG
APSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHRLMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARET
LSASLADARARGSYMGFSRLGLAIGGAIGYIGGGWLFDLGKSVHQPELPWMMLGIIGIFTFLALGWQFSQKRAARRLLER
DA
>SEQF1516_EDU83949.1 flagellar basal-body rod protein FlgF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDHAIYTAMGAASQTLNQQAVTASNLANASTPGFRAQLNALRAVPVEGLSLPTRTLVTASTPGADITPGKMDYTSRPLDV
ALQQDGWLAVQTADGSEGYTRNGSIQVDPTGQLTIQGHPVIGEAGPIAVPEGAEITIAADGTISALNPGDPANTVAPVGR
LKLVKATGSEVQRGDDGIFRLSAETQATRGPVLQADPTLRVMSGVLEGSNVNAVAAMSDMIASARRFEMQMKVISSVDDN
AGRANQLLSMS
>SEQF1516_EDU83950.1 flagellar hook-associated protein 3 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFSTQMMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPIAASQAVVLSQAQAQNSQYTLARTFATQKVSLEESVL
SQVTTAIQNAQEKIVYASNGTLSDNDRASLATDIQGLRDQLLNLANTTDGNGRYIFAGYKTETAPFSEVNGDYVGGTESI
KQQVDASRSMVIGHTGDKIFDSITSNAVAEPDGSASETNLFAMLDSAIAALKTPVADSEADKETAAAALDKTNRGLKNSL
NNVLTVRAELGTQLNELESLDSLGSDRALGQTQQMSDLVDVDWNATISSYIMQQTALQASYKAFTDMQGLSLFQLNK
>SEQF1516_EDU83951.1 flagellar basal-body rod protein FlgB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDKLDAALRFQQEALNLRAQRQEVLAANIANADTPGYQARDIDFASELKKVMQRGRNATSVVALTMTSTQHIPAQALTP
PTAELQYRIPDQPSLDGNTVDMDRERTQFADNSLQYQMSLSALSGQIKGMMNVLQSGN
>SEQF1516_EDU83952.1 rhodanese domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKATRDALYQLFTALNVFGRVYLAHEGINAQISVPASNVKTFR
AQLYAFDSALDGLRLNIALDDDGKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYE
YEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGFNKVWHIEGGIIEYARKAREQGL
PVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDSHTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRR
RRAGRENGNKIFNKSRGRLNTTLGIPDPTE
>SEQF1516_EDU83953.1 nickel-dependent hydrogenase b-type cytochrome subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFTNTPERYGVISAAFHWLSAIIVYGMFALGLWMVTLSYYDGWYHKAPELHKSIGILLMMGLVIRVLWRVISPPPGPLP
SYSPMTRLAAKAGHLALYLLLFAIGISGYLISTADGKPISVFGWFDVPATLADAGAQADFAGALHFWLAWSVVVLSVMHG
FMALKHHFIDKDDTLKRMLGKSSSDYGV
>SEQF1516_EDU83954.1 hypothetical protein ECH7EC4501_6028 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGSASEMSGECCRSRNNLIQFFTLNEREIKYLSVYVSAEN
>SEQF1516_EDU83955.1 flagella basal body P-ring formation protein FlgA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAIKRSVAIIAILFSPLSAASNLTSQLQTFFSSQLAGISDEVRVSIRTAPNLLPPCEQPLLSMSNNSRLWGNVNVLARC
GNDKRYLQVNVQATGNYVVAAMPIVRGGKLGAGNVKLKRGRLDTLPPRTVLDINQLVDAVSLRDLSPDQPIQLTQFRQAW
RVKAGQRVNVIASGDGFSANAEGQALNNAAVAQNARVRMVSGQVVSGVVDADGNILINL
>SEQF1516_EDU83956.1 flagellar basal body-associated protein FliL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDYAISKKSKRSLWIPILVFITLAACASAGYSYWHSHQVAADDKAQQRVVPSPVFYALDTFTVNLGDADRVLYIGITLR
LKDEATRSRLSEYLPEVRSRLLLLFSRQDAAVLATEEGKKNLIAEIKTTLSTPLVAGQPKQDVTDVLYTAFILR
>SEQF1516_EDU83957.1 hypothetical protein ECH7EC4501_3876 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFPLNDLSLKTQSVQLNKITSNTESTIKQHELVSDDAIINELSSELVSCLGNDKFTPVSEDSNLLNMLSEFKLLREQCFR
WGNYTLLFENYGAYDKTGSITIEKSQGEGTLPIRHKLEFISTNIAELLDKLTKITDARLCKGFSDWASSVKEGASNDLKE
NVDRALVRMFKCVKLHSNELNLSSLSLGSVPPLPEWIEMLSLVYNELDSIQVPESCKELELDFNNLTEFPQVPDGITLIS
VNNNLISYIDSFPPKAKKIFICHNKLSEIPALPDTAKVFDCSENNIKEIRWFPKNLKEAYIEYNKIEVIPAIPGNLKLLC
MKCNPIKEAFLMPWTLTGIRYEISQRKYIVMNPADYDKYSDMVKKHVIDGEEFIIKYYM
>SEQF1516_EDU83958.1 hypothetical protein ECH7EC4501_3873 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFPLNDLSLKTQSVQLNKITSNTESTIKQHELVSDDAIINELSSELVSCLGNDKFTPVSEDCNLLNMLSEFKLLREQCFR
WGNYTLLFENYESYDKTGSITIEKNQGEGTLPIRHKLEFISTNIAELLDKLTKITDARLCKGFSDWASSVKEGGSNDLKE
NVDRALVRMFKCVKLHSNELDLSYLFLGSVPPLPDWIEMLSLVYNELDSIQVPESCKELELDFNNLTEFPQVPDGITLIS
VNNNLISHIDSFPPKAKKIFISHNKLSETPAIPDTAKVFDCGYNKIQEIRYFPKNLKEARIGYNNIEVVPAIPGNLKILF
MECNPIKEAFLMPWTLTGICYEISQRKYIVTNPADYDKYSDMVKKHVIDGEELIIKYFM
>SEQF1516_EDU83959.1 flagellar protein export ATPase FliI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGLQLPLGATCVIERQNGSETHEVESEVVGFNGQRLFLM
PLEEVEGVLPGARVYAKNISAEGLQSGKQLPLGPALLGRVLDGSGKPLDGLPSPDTTETGALITPPFNPLQRTPIEHVLD
TGVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKDFIENILGAEGRARSVVIAAPAD
VSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTRYAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGG
SITAFYTVLTEGDDQQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFKQLLSSFQR
NRDLVSVGAYAKGSDPMLDKAIALWPQLEGYLQQGIFERADWEASLQGLERIFPTVS
>SEQF1516_EDU83960.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLAIAGALMLLAGCAEVENYNNVVKTPAPDWLAGYWQTKGPQRALVSPEAIGSLIVTKEGDTLDCRQWQRVIAVPGKL
TLMSDDLTNVTVKRELYEVERDGNTIEYDGMTMERVDRPTAECAAALDKAPLPTPLP
>SEQF1516_EDU83961.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIVPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK
>SEQF1516_EDU83962.1 flagellar protein FliO [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGALIAIIALILAAAWLVKRLGFAPKRTGVNGLKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHKLPPSAPTE
EIPQTDFQSVMKNLLKRSGRS
>SEQF1516_EDU83963.1 flagellar protein FliJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAGMTSNRWINYQQFIQTLEKAI
TQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE
>SEQF1516_EDU83964.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDGVIGKVEQDSLPGQQTRKIDAPIICAFVFFYPPINPFFCCYLAPLSY
>SEQF1516_EDU83965.1 FliZ protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMVQHLKRRPLSRYLKDFKHSQTHCAHCRKLLDRITLVRDGKIVNKIEISRLDTLLDENGWQTEQKSWAALCRFCGDLHC
KTQSDFFDIIGFKQFLFEQTEMSPGTVREYVVRLRRLGNHLHEQNISLDQLQDGFLDEILAPWLPTTSTNNYRIALRKYQ
HYQRQTCTGLVQKSSSLPASDIY
>SEQF1516_EDU83966.1 flagellar M-ring protein FliF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAKAPDYRTLFSNLSDQDGGAIVSQLTQMNIPYRFSEAS
GAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPS
LFVREQKSPSASVTVNLLPGRALDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLTQSNTSWRDLNDAQLKYASDVEG
RIQRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTEEQYRPNGDESQAALRSRQLNESEQSGSGYPGGVPGALSNQPAPA
NNAPISTPPANQNNRQQQASTTSNSGPRSTQRNETSNYEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGKPLPLSNEQ
MKQIEDLTREAMGFSEKRGDSLNVVNSPFNSSDESGGELPFWQQQAFIDQLLAAGRWLLVLLVAWLLWRKAVRPQLTRRA
EAMKAVQQQAQAREEVEDAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWINNDHE
>SEQF1516_EDU83967.1 flagellar protein FliT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAVQEIAHLTEEVDPSTTMQEQLRPMLRLILDNESKVKQ
LLQIRMDELAKLVGQSSVQKSVLSAYGDQGGFVLAPQDNLF
>SEQF1516_EDU83968.1 L-cystine ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMRLSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQ
FGIELDPIPSAMIGLSLNTAAYTAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQEREPK
>SEQF1516_EDU83969.1 flagellar motor switch protein FliG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSV
LVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLR
IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENLV
DVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGE
MVIGSGEDTYV
>SEQF1516_EDU83970.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGEFTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRID
GMMILGMFGGCFAAALWANNVKLRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSW
FGARFTLLPIFRIPVKMQKVAAASPLTQKPDQARRRFRLGMLVFFGMLGWALLTAMNQPKLGLAMLFGVGFGLLIERAQI
CFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYVQLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQ
VHYWWVGLGNVIGSTILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFAALMLIIGWEKRFFRRAAPQTAKEI
A
>SEQF1516_EDU83971.1 cystine-binding periplasmic protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTNNGSTLQTDITTFGVNMKLAHLGRQALMGVMAVALIAGMSVKSFADEGLLNKVKERGTLLVGLEGTYPPFSFQGDDG
KLTGFEVEFAQQLAKHLGVEASLKPTKWDGMLASLDSKRIDVVINQVTISDERKKKYDFSTPYTISGIQALVKKGNEGTI
KTADDLKGKKVGVGLGTNYEEWLRQNVQGVDVRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTNDTLAVTGEAFSR
QESGVALRKGNEDLLKAVNDAIAEMQKDGTLQALSEKWFGADVTK
>SEQF1516_EDU83972.1 hypothetical protein ECH7EC4501_3862 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMSAPLTCSSGAAETGAEDCTVAWLFITNGSGGAFAQTE
>SEQF1516_EDU83973.1 acetyltransferase, gnat family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGALKLLDDKHGELKSMRTAPNYLRRGVASLILRHILQVAHDRCLHRLSLETGTQAGFTACHQLYLKHGFVDCEPFADYQ
FDPHSRFLSLTLCEDNELP
>SEQF1516_EDU83974.1 flagellar assembly protein FliH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDNLPWKTWTPDDLAPPQAEFVPMVESEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEGLAQGL
EQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGK
PQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV
>SEQF1516_EDU83975.1 flagellar motor switch protein FliM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGDSILSQAEIDALLNGDSEVKDEPTASVSGESDIRPYDPNTQRRVVRERLQALEIINERFARHFRMGLFNLLRRSPDIT
VGAIRIQPYHEFARNLPVPTNLNLIHLKPLRGTGLVVFSPSLVFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKL
ALEGYSDAWKAINPLEVEYVRSEMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNICLPFSMIEPLRELLVNPPLENSR
NEDQNWRDNLVRQVQHSQLELVANFADISLRLSQILKLKPGDVLPIEKPDRIIAHVDGVPVLTSQYGTLNGQYALRIEHL
INPILNSLNEEQPK
>SEQF1516_EDU83976.1 hypothetical protein ECH7EC4501_3875 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWKERLWTRRFLLVINKGAARRMQECAASGSWQFIIFA
>SEQF1516_EDU83977.1 flagellar protein FliS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYAAKGTQAYAQIGVESAVMSASQQQLVTMLFDGVLSALVRARLFMQDNNQQGKGVSLSKAINIIENGLRVSLDEESKDE
LTQNLIALYSYMVRRLLQANLRNDVSAVEEVETLMRNIADAWKESLLSPSLIQDPV
>SEQF1516_EDU83978.1 flagellar biosynthetic protein FliP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGT
PSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQ
GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA
QSFYS
>SEQF1516_EDU83979.1 hypothetical protein ECH7EC4501_3887 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGEMRGYLGVTGKFQAEKTPPVAGKHVANKLRFMLPDAA
>SEQF1516_EDU83980.1 RNA polymerase sigma factor for flagellar operon [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDLLQAGGIGLLNAVERYDALQGTAFTTYAVQRIRGAML
DELRSRDWVPRSVRRNAREVAQAIGQLEQELGRNATETEVAERLGIDIADYRQMLLDTNNSQLFSYDEWREEHGDSIELV
TDDHQRENPLQQLLDSNLRQRVMEAIETLPEREKLVLTLYYQEELNLKEIGAVLEVGESRVSQLHSQAIKRLRTKLGKL
>SEQF1516_EDU83981.1 flagellin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEG
ALSEINNNLQRIRELTVQATTGTNSDSDLDSIQDEIKSRLDEIDRVSGQTQFNGVNVLAKDGSMKIQVGANDGETITIDL
KKIDSDTLGLNGFNVNGKGTITNKAATVSDLTSAGAKLNTTTGLYDLKTENTLLTTDAAFDKLGNGDKVTVGGVDYTYNA
KSGDFTTTKSTAGTGVDAAAQAADSASKRDALAATLHADVGKSVNGSYTTKDGTVSFETDSAGNITIGGSQAYVDDAGNL
TTNNAGSAAKADMKALLKAASEGSDGASLTFNGTEYTIAKATPATTTPVAPLIPGGITYQATVSKDVVLSETKAAAATSS
ITFNSGVLSKTIGFTAGESSDAAKSYVDDKGGITNVADYTVSYSVNKDNGSVTVAGYASATDTNKDYAPAIGTAVNVNSA
GKITTETTSAGSATTNPLAALDDAISSIDKFRSSLGAIQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQI
IQQAGNSVLAKANQVPQQVLSLLQG
>SEQF1516_EDU83982.1 alpha-amylase, cytoplasmic [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNPTLLQCFHWYYPEGGKLWPELAERADGFNDIGINMVWLPPAYKGASGGYSVGYDSYDLFDLGEFDQKGSIPTKYGDK
VQLLAAIDALKRNDIAVLLDVVVNHKMGADEKEAIRVQRVNADDRTQIDEEIIECEGWTRYTFPARAGQYSQFIWDFKCF
SGIDHIENPNEDGIFKIVNDYTGEGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKYWARWVMEQTQCDGFRLDAVKHI
PAWFYKEWIEHVQEVAPKPLFIVAEYWSHEVDKLQTYIDQVEGKTMLFDAPLQMKFHEASRMGRNYDMTQIFTGTLVEAD
PFHAVTLVANHDTQPLQALEAPVEPWFKPLAYALILLRENGVPSVFYPDLYGAHYEDVGGDGQTYPIDMPIIEQLDELIL
ARQRFAHGVQTLFFDHPNCIAFSRSGTDEYPGCVVVMSNGDDGEKTIHLGENYGNKTWRDFLGNRQESVVTDENGEATFF
CNGGSVSVWVIEEVL
>SEQF1516_EDU83983.1 flagellar hook-associated protein 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASISSLGVGSGLDLSSILDSLTAAQKATLTPISNQQSSFTAKLSAYGTLKSALTTFQTANTALSKADLFSATSSTTAFS
ATTAGNAIAGKYTISVTHLAQAQTLTTRTTRDDTKTAIATSDSKLTIQQGGDKDPITIDISAANSSLSGIRDAINNAKAG
VSASIINVGNGDYRLSVTSNDTGLDNAMTLSVSGDDALQSFMGYDASASSNGMEVSVAAQNAQLTVNNVAIENSSNTISD
ALENITLNLNDVTTGNQTLTITQDTSKAQTAIKDWVNAYNSLIDTFSSLTKYTAVDAGADSQSSSNGALLGDSTLRTIQT
QLKSMLSNTVSSSSYKTLAQIGITTDPSDGKLELDADKLTAALKKDASGVGALIVGDGKKTGITTTIGSNLTSWLSTTGI
IKAATDGVSKTLNKLTKDYNAASDRIDAQVARYKEQFTQLDVLMTSLNSTSSYLTQQFENNSNSK
>SEQF1516_EDU83984.1 flagellar biosynthetic protein FliR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQVTSEQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVPVFSFFALWLAVQQILI
GIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIG
GEPLNSNAFLALTKAGSLIFLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC
EHLFSEIFNLLADIISELPLI
>SEQF1516_EDU83985.1 D-cysteine desulfhydrase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTPMAMGGNKLRKLEFLAADALREGADTLITAGAIQSNH
VRQTAAVAAKLGLHCVALLENPIGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGG
SNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGVTVSRSVADQLPKVVNLQQAIAK
ELELTASVEILLWDDYFAPGYGVPNDEGMEAVKLLARLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPA
LFAYHPHV
>SEQF1516_EDU83986.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTIKTDDLTHPAVQALVAYHISGMLQQSPPESSHALDVQKLRNPTVTFWSVWEGEQLAGIGALKLLDDKHGELKSMRTA
PNYLRRGVASLILRHILQVAHDRCLHRLSLETGTQAGFTACHQLYLKHGFVDCEPFADYQLDPHSRFLSLTLCEDNELL
>SEQF1516_EDU83987.1 flagellar hook-basal body complex protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASV
SMQMGIQVRNKLVAAYQEVMSMQV
>SEQF1516_EDU83988.1 flagellar motor switch protein FliN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDMNNPADDNNGAMDDLWAEALSEQKSTSSKSAADAVFQQFGGGDVSGTLQDIDLIMDIPVKLTVELGRTRMTIKELLR
LTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGVRITDIITPSERMRRLSR
>SEQF1516_EDU83989.1 flagellar hook-length control protein Flik [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTKGEPLISDIVSDAQQANLLIP
VDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKADDLNEDVTASLSALFAMLPGFDNTPKVTDVPSTVLPAEKP
TLFTKLTSAQLTTAQPDDAPGTPAQPLTPQVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW
QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSSHQHVRAALEAALPVLRTQLAESGIQLGQSNI
SGESFSGQQQAASQQQQSQRTVNHEPLAGEDDDTLPVPVSLQGRVTGNSGVDIFA
>SEQF1516_EDU83990.1 flagellar biosynthetic protein FliQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQINEMTLSFIPKIIAVFIAIIIAGPWMLNLLLDYVRTL
FTNLPYIIG
>SEQF1516_EDU83991.1 amino acid ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRSINLLEQPEAGTITVGDITIDTARSLSQQKSLI
RQLRQHVGFVFQNFNLFPHRTVLENIIEGPVIVKGEPKEEATARARKLLAKVGLAGKETSYPRRLSGGQQQRVAIARALA
MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGAAKALFADPEQPRT
RQFLEKFLLQ
>SEQF1516_EDU83992.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKVLLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVET
AATSRMFKPLWQHGRAICFADGWFEWKKEGDKKQPYFIYRADGQPVFMAAIGSTPFERGDEAEGFLIVTAAADQGLVDIH
DRRPLVLSPEAAREWMRQEISGKEASEIAASGCVPANQFSWHPVSRAVGNVKNQGAELIQPV
>SEQF1516_EDU83993.1 YcgR family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHYHEQFLKQNPLAVLGVLRDLHKAAIPLRLSWIGGQLISKILVITPDKLVLDFGSQAEDNIAVLKAQHITITAETQGA
KVEFTVEQLQQSEYLQLPAFITVPPPTLWFVQRRRYFRISAPLHPPYFCQTKLADNSTLRFRLYDLSLGGMGALLETAKP
AGLHEGMRFAQIEVNMGQWGVFHFDAQLISISERKVID
>SEQF1516_EDU83994.1 PTS-dependent dihydroxyacetone kinase, DhaL subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLSRTQIVNWLTRCGDIFNTESEYLTGLDREIGDADHGLNMNRGFSKVVEKLPAIADKDIGFILKNTGMTLLSCVGGAS
GPLFGTFFIRAAQATQARQSLTLEELYQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPAALEAASS
IAEFAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE
>SEQF1516_EDU83995.1 PTS-dependent dihydroxyacetone kinase, DhaM subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNLVIVSHSSRLGEGVGELARQMLMSDNCKIAIAAGIDDPQNPIGTDAVKVMEAIESVADADHVLVMMDMGSALLSAET
ALELLAPEIAAKVRLCAAPLVEGTLAATVSAASGAEIDKVIFDAMHALEAKREQLGLPSSDTEISDSCPAYDEEARSLAV
VIKNRNGLHVRPASRLVYTLSTFNADMLLEKNGKCVTPESINQIALLQVRYNDTLRLIAKGPEAEEALIAFRQLAEDNFG
ETEEVAPPTLRPVPPVSGKAFYYQPVLCTVQAKSPLTVEEEQERLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSGHHT
LLDDPELLAAASELLQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTKEELPQFNSPTILL
AENIYPSPVLQLDPAVVKGICLSAGSPVSHSALIARELGIGWICQQGEKLYAIQPEEKLTLDVKTQRFNRQG
>SEQF1516_EDU83996.1 iron(III) ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLLAVRHASLGYSRHPVLRDVSFTLSQGTICCLLGANGCGKTTLMRSILGVIPLLKGEVLLDSLPVQTLSHRQRAQAIA
WVPQAHDGIFAFSVLDMVLMGLAPTIGAFSVPGKQERLKATEQLEKLGILHLAARRWNTLSGGERQLALIARALVQQPRL
LLLDEPASSLDFGHQIQLLDTLAQLKNNGMTMLMSTHHPLHANAIADSIIQVEPDGRVTQGLPTEQLTTNKLAALYRVSA
DQIHHHLSAISH
>SEQF1516_EDU83997.1 peptidyl-tRNA hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAKFFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMAS
FFRINPDEILVAHDELDLPPGVAKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQK
LIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ
>SEQF1516_EDU83998.1 glutamyl-tRNA reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGGVVLSTCNRTELW
>SEQF1516_EDU83999.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLFSYIREDFNFILFYFINLLISTPLFIFFATPPFSLTIFLWNKVLFKQQANHSVSLDKF
>SEQF1516_EDU84000.1 hypothetical protein ECH7EC4501_5879 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDTISPEPELTAQAFYIKRLRFIVDSNSTSDKSRFTLDADSGSCSEC
>SEQF1516_EDU84001.1 sulfate permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAIPLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRF
SVSGPTAAFVVILYPVSQQFGLAGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCAVMGIVNLLGGHVATIGSQFHYV
LADGSQGNGIPQLLPQLVLPWDLPNSEFTLTWDSIRTLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLG
NIIAPFFGGITATAAIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSEAHKVVDLL
RHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAPVVVDVPDDVLVLRVIGPLFFAAAEGLFTDL
ESRLEGKRIVILKWDAVPVLDAGGLDAFQRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL
>SEQF1516_EDU84002.1 transglycosylase-associated protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGIIAWIIFGLIAGIIAKLIMPGRDGGGFFLTCILGIVGAVVGGWLATMFGIGGSISGFNLHSFLVAVVGAILVLGVFRL
LRRE
>SEQF1516_EDU84003.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRKNASLLGNVLMGLGLVVMVVGVGYSILNQLPQFNMPQYFAHGAVLSIFVGAILWLAGARVGGHEQVCDRYWWVRHYD
KRCRRSDNRRHS
>SEQF1516_EDU84004.1 muramoyltetrapeptide carboxypeptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLFHLIAPSGYCIKQHAALRGIQRLTDAGHQVNNVEVIARRCERFAGTETERLEDLNSLARLTTPNTIVLAVRGGYGAS
RLLADIDWQALVARQQYDPLLICGHSDFTAIQCGLLAQGNVITFSGPMLVANFGADELNTFTEHHFWLALRNETFTIEWQ
GEGPTCRAEGTLWGGNLAMLISLIGTPWMPKIENGILVLEDINEHPFRVERMLLQLYHAGILPRQKAIILGSFSGSTPND
YDAGYNLESVYAFLRSRLSIPLITGLDFGHEQRTVTLPLGAHAILTNTREGTQLTISGHPVLKM
>SEQF1516_EDU84005.1 modD protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIFLSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFLRQGGCVSGVSVACKMLTTLGLTIDDAVSDGSQANAGQRLI
RAQGNAAALHQGWKAIQNVLEWSCGVSDYLDQMLALLRERYPDGNIACTRKAIPGTRLLASQAILAAGGLIHRAGCAETI
LLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKFSPQQATEIAQIAPSLAPHCTLA
LTGGINLTTLKNYLDCGIRLFITSAPYYAAPADIKVSLQPAASI
>SEQF1516_EDU84006.1 membrane-bound lytic murein transglycosylase E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQKAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGL
MQLKASTSGRDVYRRMGWSGEPTTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
RKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM
>SEQF1516_EDU84007.1 ribose-phosphate pyrophosphokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQINENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRA
SAGRITAVIPYFGYARQDRRVRSARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN
LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVLVDDMIDTGGTLCKAAEALKERG
AKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIPLSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH
>SEQF1516_EDU84008.1 iron(III) ABC transporter, periplasmic iron(III)-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLTRRRFTQILASTLFLHHLPSFAQSVKFWASLTLPEAQNITRIVSAGAPADLLLLAVAPEKMVGFSSFDFARQALIPL
SEHIRQLPRLGRLAGRASTLSLEGLMALHPDLVVDCGNTDETWISQARQVSEQTQIPWLLLNGKLAQSAEQLTTLGKTLG
EEHRAAEQANLASRFVGEAQAFAASPAANLRFYAARGPRGLETGLKGSLHTEAAELLGLHNVAQIADRQGLTQVSMENLL
RWQPDIILVQEAVTADFIRRDPLWHGVKAVAEQRILFLSGLPFGWLDAPPGINRLLGLRRLHAWLDPAINRQFKSDMQHY
AQLFWHCSLSDADYQKLVAT
>SEQF1516_EDU84009.1 4-diphosphocytidyl-2C-methyl-D-erythritol kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIELRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAAD
SGRLPTGSGANISIDKRLPMGGGLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEIL
TPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKRFREVDAVLSWLLEYAPSRLTGT
GACVFAEFDTESEARQVLEQAPEWLNGFVAKGANLSPLHRAML
>SEQF1516_EDU84010.1 alanine racemase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRPIQASLDLQALKQNLSIVRQAAPHARVWSVVKANAYGHGIERIWSALGATDGFALLNLEEAITLRERGWKGPILMLE
GFFHAQDLEMYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHF
AEAEHPDGISGAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSEII
GVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPV
ELWGKEIKIDDVAAAAGTVGYELMCALALRVPVVTV
>SEQF1516_EDU84011.1 cell volume regulation protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRT
QASSFRVALGPALSLATLGVLITSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIGLGGGYLLLQMINRIALPAGLYPLLALSGGILIFALTTA
LEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFA
GLLPFRGFNLRERVFISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKVVVPPVGRP
VSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDNQLLHPTGSTRLREGDVLCVIGRERDLPALG
KLFSQSPPVALDQRFFGDFILEASAKYADVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKE
DNEVLKIGVRVAEEEAES
>SEQF1516_EDU84012.1 hypothetical protein ECH7EC4501_5901 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYLHNKNNMRHFCITNKKKQKTSIFIFGQWVFWSIVVIVLLVIIFILPGSHVITLFGDFICGILPFR
>SEQF1516_EDU84013.1 iron(III) ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIVNGCILLLAAISITFAAVSGAYHLDMQQLLALILRQENVPVQEQIVFWQIRVPRILAALLLGAALAGAGTTYQGMLR
NPLVSPDILGVSAGAGLGACTAILWGLSIVYIQLYAFCGGLMVVAGVWLITRRVTRHDPILTLVLVGIALGTLCGAGISL
IKTLADPYTQLPSITFWLLGGLSTVTLRDLCYAAPIILIGSLPLFFLRWRMNLLTLSDDEARSLGLNVTRLRFVLIVCAT
LITASTVAIAGIIGWVGLVVPHIARLLTGHNHQQLLPMAMCTGAILLLLTDTLARSIGTTEIPLGILTAFVGAPFFLLLL
LRGGRQ
>SEQF1516_EDU84014.1 TonB-dependent receptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLKKHYLCTALSLAFTQQAVAAQESDSLTVWSSPVSSTTTTVLDQPTMKALDKQNVAQALSVVPGVVLQKSGSRNEEQV
KVRGFDSRQVPVYFDGVPIYVPYDGNLDLARILTNNLGAVEVSKGYSSLLQGPNQMGGAINITTQKPTKPLEASLGYRQG
WSRSQDNAYDMHASFAASSELGYLQVSGSQLKQDFLGLPHGVNNDIAGKHGKMINSSADDKRGIVKLGFTPRENDEYTLT
YIKQDGEKDNPPYSGNSGQKSRYWQWPEYDKESFYYQGTTQLNDRFTLKSRLYRDTFENTLMMYNSLADLKNKKGSYSHY
SDYSDGAGLQLAADVRENDLLTFAVNWKDDVHREKGAPHAAYDRYEDRTWSLASEYQWAAADNVDVVAGISYDWRDSVEA
KKHEKDGSITHYDDNNQSAFNWQVMGKYHFVNEDTLALSYYDRKRFPTLKERYTTSKPAYNQIAIVNPQLKPERARGVDL
TWNGAFTHDWGFEVSVYYNRVSDAILSHNIDADTIQNQNSGTVDYSGLDAGIKGKISNILDVGLSYALIHADAKRKDIGK
ITDLPTQTMTAWMTLKPWEPLSVTLSEEARSSSYSNSDGSQKAAGFAVTHIRADYTLGHGFSVNASVNNLFDTQYAYSEG
FVEEGRNFWAGVEYTF
>SEQF1516_EDU84015.1 GTP-binding protein EngD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVVPMPDPRLDQLAEIVKPQRTLPTTMEFVDIAGLVKGA
SKGEGLGNQFLTNIRETEAIGHVVRCFENDNIIHVSGKVNPADDIEVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
ELAVLEKCLPQLENAGMLRALDLSAEEKAAIRYLSFLTLKPTMYIANVNEDGFENNPYLDQVREIAAKEGSVVVPVCAAV
EADIAELDDEERDEFMQELGLEEPGLNRVIRAGYKLLNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQ
TISFEDFITYKGEQGAKEAGKMRAEGKDYIVKDGDVMNFLFNV
>SEQF1516_EDU84016.1 PTS-dependent dihydroxyacetone kinase, DhaK subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLINDVQDVLDEQLAGLAKAHPSLTLHQDPVYVTRADAPVAGKVALLSGGGSGHEPMHCGYIGQGMLSGACPGEIFTS
PTPDKIFECAMQVDGGEGVLLIIKNYTGDILNFETATELLHDSGVKVTTVVIDDDVAVKDSLYTAGRRGVANTVLIEKLV
GAAAERGDSLDACAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIHGEPGIDRRPFSSLDQTVDEMFD
TLLENGSYHRTLRFWDYQQGSWQEEPQTKQPLQSGDGVIALVNNLGATPLSELYGVYNRLTTRCQQAGLTIERNLIGAYC
TSLDMTGFSITLLKVDDETLALWDAPVHTPALNWGK
>SEQF1516_EDU84017.1 gifsy-1 prophage VmtT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSFSDVWMDAQFASLKALIVRMVSGSSDAAVADFSLLPEENGIPERTDEELMHLGEGISGGVRYGPDSQPGH
>SEQF1516_EDU84018.1 outer membrane lipoprotein LolB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQDVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDR
YRLLLTNPLGSTELELNAQPGNVQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILCLPGDATDYKLDDQYRLSEI
TYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK
>SEQF1516_EDU84019.1 IS1203 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKKEIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVAACDRVNRQFVAERPDQLWVADFTWVSTWQGFVYVAFIIDVFAGYI
VGWQVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRTEVELATLTWVDWYNNRRLLERLGHIPPAEAEKAYYASIGNNDLAA
>SEQF1516_EDU84020.1 IS1203 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAVRMVLESQGEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGSGDGGLTTAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU84021.1 sirB1 protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRSLADFEFNKAPLCEGMILACEAIRRDFPSQDVYDELERLVSLAKEEISQLLPLEEQLEKLIALFYGDWGFKASRGVYR
LSDALWLDQVLKNRQGSAVSLGAVLLWVANRLDLPLLPVIFPTQLILRIECPDGEIWLINPFNGESLSEHMLDVWLKGNI
SPSAELFYEDLDEADNIEVIRKLLDTLKASLMEENQMELALRTSEALLQFNPEDPYEIRDRGLIYAQLDCEHVALNDLSY
FVEQCPEDPISEMIRAQINNIAHKHIVLH
>SEQF1516_EDU84022.1 nitrate reductase molybdenum cofactor assembly chaperone 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIELVIVSRLLEYPDAALWQHQQEMFEAIAASKNLPKEDAHALGIFLRDLTTMDPLDAQAQYSELFDRGRATSLLLFEHV
HGESRDRGQAMVDLLAQYEQHGLQLNSRELPDHLPLYLEYLAQLPQSEAVEGLKDIAPILALLSARLQQRESRYAVLFDL
LLKLANTAIDSDKVAEKIADEARDDTPQALDAVWEEEQVKFFADKGCGDSAITAHQRRFAGAVAPQYLNITTGGQH
>SEQF1516_EDU84023.1 nitrate reductase 1, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDKIVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPR
TRPDLPNHEPRGCPRGASYSWYLYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVR
SSWQEVNELIAASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFYDWYCDLPPASPQTWGEQTDVPE
SADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHL
DNPSQYFTDYVRRYTDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIGFRWGEKGK
WNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELENVLLHKLPVKRLQLADGSTALVTTVYDLTLA
NYGLERGLNDVNCATSYDDVKAYTPAWAEQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLIN
MLIFCGCVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETVTAEELLSPMADKSRYT
GHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVDYTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGS
SGKGHEFMLKYLLGTEHGIQGKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDMNT
SDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHDSAAELAQPLDVKDWKKGECDLIPG
KTAPHIMVVERDYPATYERFTSIGPLMEKIGNGGKGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLA
PETNGQVAVKAWAALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNVHELIPWRTLS
GRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKEVIGQKSNGNPEKALNFLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWL
SEADAKDLGIADNDWIEVFNSNGALTARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIG
GYAHLAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQESVK
>SEQF1516_EDU84024.1 calcium/proton antiporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNAQEAVKTRHKETSLIFPVLALVVLFLWGSSQTLPVVIAINLLALIGILSSAFSVVRHADVLAHRLGEPYGSLILSLS
VVILEVSLISALMATGDAAPTLMRDTLYSIIMIVTGGLVGFSLLLGGRKFATQYMNLFGIKQYLIALFPLAIIVLVFPMA
LPAANFSTGQALLVALISAAMYGVFLLIQTKTHQSLFVYEHEDDSDDDDPHHGKPSAHSSLWHAIWLIIHLIAVIAVTKM
NASPLETLLDSMNAPVAFTGFLVALLILSPEGLGALKAVLNNQVQRAMNLFFGSVLATISLTVPVVTLIAFMTGNELQFA
LGAPEMVVMVASLVLCHISFSTGRTNVLNGAAHLALFAAYLMTIFA
>SEQF1516_EDU84025.1 nitrate reductase 1, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGVEYAWFNNVETKPGQGFPTDWENQEKYKGGWIRKINGKLQPRMGN
RAMLLGKIFANPHLPGIDDYYEPFDFDYQNLHTAPEGSKSQPIARPRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKN
FDNIQKAMYSQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCRGWRMCITGCPYKKIYFNWKSGK
SEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYDADAIERAASTENEKDLYQRQLEVFLDPNDPKVIEQAIKDGIPLS
VIEAAQQSPVYKMAMEWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLANLLTAGDTK
PVLRALKRMLAMRHYKRAETVDGKVDTRALEEVGLTEAQAQEMYRYLAIANYEDRFVVPSSHRELAREAFPEKNGCGFTF
GDGCHGSDTKFNLFNSRRIDAIDVTSKTEPHP
>SEQF1516_EDU84026.1 putative Invasion gene expression up-regulator SirB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIVPPVVDTVLLLSGIALMAKAHILPFSGQAQWLTEKLF
GVIIYIVLGFIALDYRRMHSQQARIIAFPLTLVVLYIIIKLATTKVPLLG
>SEQF1516_EDU84027.1 respiratory nitrate reductase 1, gamma subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQFLNMFFFDIYPYIAGAVFLIGSWLRYDYGQYTWRAASSQMLDRKGMNLASNLFHIGILGIFVGHFFGMLTPHWMYEAW
LPIEVKQKMAMFAGGASGVLCLIGGVLLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLV
GWAQSVVTFHGGASQHLDGVAFIFRLHLVLGMTLFLLFPFSRLVHIWSVPVEYLTRKYQLVRARH
>SEQF1516_EDU84028.1 phospholipase, patatin family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATIAFQGNLAGIMRKIKIGLALGSGAARGWSHIGVINALKKVGIEIDIVAGCSIGSLVGAAYACDRLSALEDWVTSFSY
WDVLRLMDLSWQRGGLLRGERVFNQYREIMPETEIENCSRRFAAVATNLSTGRELWFTEGDLHLAIRASCSIPGLMAPVA
HNGYWLVDGAVVNPIPISLTRALGADIVIAVDLQHDAHLMQQDLLSFNVSEENSENGDSLPWHARLKERLGSITTRRAVT
APTATEIMTTSIQVLENRLKRNRMAGDPPDILIQPVCPQISTLDFHRAHAAIAAGQLAVEKKMDELLPLVRTNI
>SEQF1516_EDU84029.1 peptide chain release factor 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQLSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQD
ELREAKEKSEQLEQQLQVLLLPKDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYK
EIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDINPADLRIDTFRSSGAGGQHVNTT
DSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGARIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDH
RINLTLYRLDEVMEGKLDMLIEPIIQEHQADQLAALSEQE
>SEQF1516_EDU84030.1 hypothetical protein ECH7EC4501_1124 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNNLNECDDTFWNGSILGYWLKYTHTRKELLLICRVVSSFTSVRVGILQHREKSHNFYEITVLTMGNDKYQ
>SEQF1516_EDU84031.1 hypothetical protein ECH7EC4501_1110 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQEVLTSRAAKSSVQIGLYAASFLANFMKRYLLAAQNKEQF
>SEQF1516_EDU84032.1 response regulator receiver domain [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQT
PVLVISATENMADIAKALRLGVEDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQEL
QPPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALLLRALFNGLLQEQLAHQNQRLPE
LGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLILVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQ
CQIWGTGGRLRLMLSAE
>SEQF1516_EDU84033.1 H-NS histone family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEESAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLA
AVKSGTKAKRAQRPAKYSYVDENGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ
>SEQF1516_EDU84034.1 nitrate/nitrite sensor protein NarX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSAHAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQT
AFSAELTRAAERDGQLAQLQGLQDYWRNELIPALMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMA
VFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNNMSAELAESYAVLEQRVQEKTAG
LEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQNLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGV
LPVGDRGTTLKWRLADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERATIARELHD
SIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPV
KLDYQLPPRLVPSHQAIHLLQIAREALSNALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRA
QSLRGDCRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE
>SEQF1516_EDU84035.1 UTP-glucose-1-phosphate uridylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAINTKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQYVVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEA
MLEKRVKRQLLDEVQSICPPHVTIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFD
ETGHSQIMVEPVADVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRYVLSADIWPLLAKTPPGAGDEIQ
LTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAFVEYGIRHNTLGTEFKAWLEEEMGIKK
>SEQF1516_EDU84036.1 dsrE family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKIVIVANGAPYGSESLFNSLRLAIALREQESNLDLRLFLMSDAVTAGLRGQKPGEGYNIQQMLEILTAQNVPVKLCKT
CTDGRGISTLPLIDGVEIGTLVELAQWTLSADKVLTF
>SEQF1516_EDU84037.1 3-deoxy-8-phosphooctulonate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTVTQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKI
FQELKQTFGVKIITDVHEPSQAQPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGN
EKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRRAQVAELARAGMAVGLAGLFIEA
HPDPEHAKCDGPSALPLAKLEPFLRQMKAIDDLVKGFEELDTSK
>SEQF1516_EDU84038.1 putative invasin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFFHFLPEVTDVLSRFVPRIIPFYLLLLAAGGTANAQSTFEQKAANPFDNNNDGLPDLGMAPENHDGEKHFAEIVKDFGE
TSMNDNGLDTGEQAKAFALGKVRDALSQQVNQHVESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDNDRYLTWSQLG
LTQQDDGLVSNVGVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANFYQPFAAWHEQTATQEQRMARG
YDLTARMRMPFYQHLNTSVSVEQYFGDRVDLFNSGTGYHNPVALSLGLNYTPVPLVTVTAQHKQGESGENQNNLGLNLNY
RFGVPLKKQLSAGEVAESQSLRGSRYDNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQIRSRYGIRQLIWQ
GDTQILSLTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVVEDNQGQRVSSNEITLTLVEPFDALSNDELRWEP
>SEQF1516_EDU84039.1 aldehyde-alcohol dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAADARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAY
KDEKTCGVLSEDDTFGTITIAEPIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAA
GAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTPVVIDETADIKRAVASVLMSKTF
DNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQGKELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILI
GEVTVVDESEPFAHEKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTARILINTPA
SQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAENMLWHKLPKSIYFRRGSLPIALDEVITDGHK
RALIVTDRFLFNNGYADQITSVLKAAGVETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYE
HPETHFEELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLADYALTPDMAIVDANLVM
DMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLLKEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLG
VCHSMAHKLGSQFHIPHGLANALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKLLA
WLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQILLDTYYGRDYVEGETAAKKEAAP
AKAEKKAKKSA
>SEQF1516_EDU84040.1 nitrate/nitrite response regulator protein NarL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNQEPATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMNGLETLDKLREKSLS
GRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRE
RDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF
>SEQF1516_EDU84041.1 chaB protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPYKTKSDLPESVKHVLPSHAQDIYKEAFNSAWDQYKDKEDRRDDASREETAHKVAWAAVKHEYAKGDDDKWHKKS
>SEQF1516_EDU84042.1 SEC-C motif domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFPGRLFVSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQDADYLIKTWHPSCGAAALRAELIAGFAHT
EWLGLTVFEHCWQDADNIGFVSFVARFTEGGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ
>SEQF1516_EDU84043.1 formyltetrahydrofolate deformylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHRTGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELN
PAGRRRIVILVTKEAHCLGDLLMKANYGGLDVEIAAVIGNHDTLRSLVERFDIPFELVSHEGLSRNEHDQKMADAIDAYQ
PDYVVLAKYMRVLTPEFVSRFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAHYVNDNLDEGPIIMQDVIHVDHT
YTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNRTIIL
>SEQF1516_EDU84044.1 nitrite extrusion protein 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHSSAPERATGAVITDWRPEDPAFWQQRGQRIASRNLWISVPCLLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTAL
PSVSGALLRVPYSFMVPIFGGRRWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPK
QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWIWGPFLAIFTIAAWFGMNDLATS
KASIKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRV
TLVNFILMAIFSGLLFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSDERAMREAA
TDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACVVITWAVYGRHSKK
>SEQF1516_EDU84045.1 protein-(glutamine-N5) methyltransferase, release factor-specific [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEYQHWLREAISQLQASESPRRDAEILLEHVTGRGRTFILAFGETQLTDEQCQQLDALLTRRRDGEPIAHLTGVREFWSL
PLFVSPATLIPRPDTECLVEQALARLPEQPCRILDLGTGTGAIALALARERPDCEITAVDRMPDAVALAQRNAQHLAIKN
IHILQSDWFSALAGQQFAMIVSNPPYIDEQDPHLQQGDVRFEPLTALVAADSGMADIVHIIEQSRNALVSGGFLLLEHGW
QQGEAVRQAFILAGYHDVETCRDYGDNERVTLGRYYQ
>SEQF1516_EDU84046.1 thymidine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRFGAGKVSSRIGLSSPAKLFNQNSSLFDEIRAEHEQQA
IHCVLVDECQFLTRQQVYELSEVVDQLDIPVLCYGLRTDFRGELFIGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQA
GRPYNEGEQVVIGGNERYVSVCRKHYKEALQVGSLTAIQERHRHD
>SEQF1516_EDU84047.1 ferrichrome-iron receptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVELKEDTITVTAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVP
QSISVVTAEEMALHQPKSVKEALSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDALDDDGVYSYRLTGLARSANAQQKG
SEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGYYGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFD
HEFNDTFTVRQNLRFAENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDTQLQSKFAT
GDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLDLYNPVNTDFDFNAKDPANSGPYRILNKQKQTGVYVQDQAQWDKVLV
TLGGRYDWADQESLNRVAGTTDKRDDKQFTWRGGVNYLFDNGVTPYFSYSESFEPSSQVGKDGNIFAPSKGKQYEVGVKY
VPEDRPIVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYTDAEYTTDTTYKGNTPA
QVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANSFKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDRE
YVASCFNTYGCFWGAERQVVATATFRF
>SEQF1516_EDU84048.1 H(+)/Cl(-) exchange transporter ClcA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLT
VAFLCSAVLAMFGYFLVRKYAPEAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
MVLDVFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAVFIGVIMSTIMYRIFNHEVALID
VGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGMQDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLI
PIATAGNFSMGMLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIAGMGALLAA
SIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILARTLAKQEAEQLARSKAASASENT
>SEQF1516_EDU84049.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALRVAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAES
RYFDKVPMKFADYDEARFQKEGFRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRETGDIHYGRVPAGSVVVSGNLPS
KDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID
>SEQF1516_EDU84050.1 methionine aminopeptidase, type I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHG
IPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVV
TDNGCEILTLRKDDTIPAIISHDE
>SEQF1516_EDU84051.1 carbohydrate diacid regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERIGELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINL
PLRLEGEIVGVIGLTGEPENLRKYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNSFGRWDVEDHRKRVEQLITRMKE
YGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQRMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKAMDNN
GLLRRTLAAWFRHNVQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER
>SEQF1516_EDU84052.1 ferrichrome transport ATP-binding protein FhuC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSS
KAFARKVAYLPQQLPPAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAEIMRGET
LEMIYGIPMGILPHPAGAAPVSFVY
>SEQF1516_EDU84053.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKGAICRPPNQTCTTWSIRALPLHISRRRCVIFARSSRSLTDVSSREFSSLPPFCNSNYFGGVIKPYYSASTKLSSAWE
ARS
>SEQF1516_EDU84054.1 ATP-dependent helicase HrpB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQCGAKNVNPLERFVSSLPVAAVLPELLTALDYAPQVLLSAPTGAGKSTWLPLQLLAHPGINGKIILLEPRRLAARNVA
QRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEGVLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQG
LRDDLKLLIMSATLDNDRLQQMLPEAPVVISEGRSFPVERRYLPLPTHQRFDDAVAVATAEMLRQESGSLLLFLPGVGEI
QRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAETSLTIEGIRLVVDCAQERVARFDPRTGLT
RLITQRISQASMTQRAGRAGRLEPGICLHLIAKEQAERATAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPTVN
LLAAKRLLQMLGALDGERLSAQGQKMAALGNDPRLAAMLVSAKSDDEAATAAKIAAILEEPPRMGNSDLGVAFSRNQPAW
QQRSQQLLKRLNVRGGEADSSLIAPLLAGAFADRIARRRGQDGRYQLANGMGAMLDADDALSRHEWLIAPLLLQGSASPD
ARILLALPVDIDELVQRCPQLVQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIRDKGLSVLN
WTAEAEQLRLRLLCAGKWLPEYDWPAVDDESLLATLETWLLPHMAGVHSLRGLKSLDIYQALRGLLDWGMQQRLDSELPA
HYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEATNPTIAQGRVPLVLELLSPAQRPLQITRDLGAFWKGAYREVQKEMKG
RYPKHVWPDDPANTAPTRRTKKYS
>SEQF1516_EDU84055.1 2'-5' RNA ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDPQRLFFAIDLPAEIREQIIHWRATHFPLEAGRPVAADNLHLTLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAG
QWLRSRVVWLGMRQPPRGLIQLANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYAVTEFTLYASSFA
RGRTRYTPLKRWVLTQ
>SEQF1516_EDU84056.1 ribosome releasing factor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEYYGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEK
AIMASDLGLNPNSAGSDIRVPLPPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
QKLTDAAIKKIEAALADKEAELMQF
>SEQF1516_EDU84057.1 translation elongation factor Ts [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQT
DFVAKDAGFQAFADKVLDAAVAGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSK
TVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEVAAMSKQS
>SEQF1516_EDU84058.1 ferrichrome-binding periplasmic protein FhuD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPESVID
VGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYED
FIRSMNPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH
DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA
>SEQF1516_EDU84059.1 iron-sulfur cluster assembly accessory protein YadR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSGFQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLV
GGSVDYTEGLEGSRFIVTNPNAKSTCGCGSSFSI
>SEQF1516_EDU84060.1 UMP kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKELVELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMG
MLATVMNGLAMRDALHRAYVNARLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVFNMNKPGALRRVVMGEKEGTLIT
E
>SEQF1516_EDU84061.1 glutamyl-Q tRNA(Asp) synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPPYFLFKEMTDTQYIGRFAPSPSGELHFGSLIAALGSYLQARARHGRWLVRIEDIDPPREVPGAAETILRQLEHYGLH
WDGDVLWQSQRHHAYREALAWLHEQGLSYYCTCTRARIQSIGGIYDGHCRVLHHGPDNAAVRIRQQHPVTQFTDQLRGII
HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVSEIVRGADLIEPTVRQISLYQLFGWKVPDYIHLPLALNPQGAKLS
KQNHAPALPKGDPRPVLIAALQFLGQQAEAHWQDFSVEQILQSAVKNWRLTAVPESAIVNSTFSNASC
>SEQF1516_EDU84062.1 protease Do [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPMLEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDS
PFCQEGSPFQSSPFCQGGQGGNGGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNAENYENFIQTDAAINRGNSGGAL
VNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNLTSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVL
PNSSAAKAGIKAGDVITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSSSIFNGIEGA
EMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKVLDSKPSVLALNIQRGDSTIYLLMQ
>SEQF1516_EDU84063.1 protein-P-II uridylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQRWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAG
FSQIADLALVAVGGYGRGELHPLSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPDIKSSPGGLRDIHTLQWVARRHF
GATSLDEMVGFGFLTSAERAELNECLHILWRIRFALHLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVT
RRVSELNQMLLQLFDEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGIYSTTLRQL
RHARRHLQQPLCNIPQARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQWSHIVGQMQFDLFHAYTVDEHTIRVMLKLE
SFASEETRQRHPLCVNVWPRLPSTELIFIAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMS
VTAQRRDIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQLRRGMQNTPDMRERVR
HHQLQALALLRMDNIDEEVLHQIWSRCRANYFVRHSPNQLAWHARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYL
FAAVCAELDRRNLSVHDAQIFTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHFTV
ETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVEDLFIIATADRRALNNELQQEVHQRL
TEALNPNDKG
>SEQF1516_EDU84064.1 glutamate-1-semialdehyde-2,1-aminomutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYLYDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAE
RGLSFGAPTEMEVKMAQLVTELVPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPDFLPGLRALCDEFGALLIIDEVM
TGFRVALAGAQDYYGVEPDLTCLGKIIGGGMPVGAFGGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGV
HETLDELTTRLAEGLLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVYLAPSAFEA
GFMSVAHSMEDINNTIDAARRVFAKL
>SEQF1516_EDU84065.1 MTA/SAH nucleosidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVALLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGL
APTLKVGDIVVSDEARYHDADVTAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQSSLMVESLVQKLAHG
>SEQF1516_EDU84066.1 cobalamin ABC transporter, periplasmic cobalamin-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITPVGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPD
LVIAWRGGNAERQVDQLASLGIKVMWVDATNIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGPDQIPKIKQYWGEQLKIPVIPLT
SDWFERASPRIILAAQQLCNALSQVD
>SEQF1516_EDU84067.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAKSVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYII
DELDQICQRDRSEVDLKRKILDDLRHLESVVTNKISEIEADLEKLTRK
>SEQF1516_EDU84068.1 deoxyguanosinetriphosphate triphosphohydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPAIRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYI
AKEILSRLKELKLLEAYGLDELTGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAVL
RLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWWRGETPETHHYLMKKPGYYLSEE
AYIARLRKELNLALYSRFPLTWIMEAADDISYCVADLEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSR
SNSLSRSTEDQFFMYLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFSHPDVEQLE
LQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRSPIESRLFHKLSTRHRLAYVEAVSKLPSDSPEFPLWEYYYRCRL
LQDYISGMTDLYAWDEYRRLMAVEQ
>SEQF1516_EDU84069.1 ribosomal protein S2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLEKTVPMFNEALAELNKIASRKGKILFVGTKRAASEAV
KDAALSCDQFFVNHRWLGGMLTNWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVAATVREGRSQDLASQAEESFVEA
E
>SEQF1516_EDU84070.1 ferrichrome ABC transporter, permease protein FhuB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKRIALFPALLLALLVIAATALTWMNFSQALPRSQWAQAAWSPDIDVIEQMIFHYSLLPRLAISLLVGAGLGLVGVLFQ
QVLRNPLAEPTTLGVATGAQLGITVTTLWAIPGAMASQFAALAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLDDGVARNLGLALSLARLAALSLA
IVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPRLMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLL
WLLPRLRSISAPDMKVNDRVAAERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWPRIMAALFA
GVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWLLPAGSIGAAVTLLIIMIAAGRGGFSPHRML
LAGMALSTAFTMLLMMLQASGDPRMAQVLTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGV
ALTPTRIALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFADWCGRMVLFPFQIPAG
LLSTFIGAPYFIYLLRKQSR
>SEQF1516_EDU84071.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGGTIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVR
QPRHLPKWMLPVLDAVGLAVFVGIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR
>SEQF1516_EDU84072.1 sugar fermentation stimulation protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGCATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAFICV
NTLWANRLTKEAILNESISELSGYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAEISAEGMALKKSLPVTL
>SEQF1516_EDU84073.1 penicillin-binding protein 1B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEEPMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLI
AIYGVYLDQKIRSRIDGKVWQLPAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
FPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPRSGFPDLLVDTLLATEDRHFYEH
DGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNLFLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSG
DNEIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYDMLSARPLG
VQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAAEKAAVEGIPALKKQRKLSDLETAIVVVDRF
SGEVRAMVGGSEPQFAGYNRAMQARRSIGSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSES
GRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQAFQTIASGGNRAPLSAL
RSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGTGRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTI
TWVGRDNNQPTKLYGASGAMSIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRVLPVWTSDPQSLCQQSEMQ
QQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDMFGSN
>SEQF1516_EDU84074.1 transporter auxiliary protein, membrane fusion protein (MFP) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTVNLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYE
IALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQAT
LKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRAVEPGTVLNEGGTVFTVSLTRPV
WVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPV
TVQFGDEAGHE
>SEQF1516_EDU84075.1 hypothetical protein ECH7EC4501_1405 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQFELLLITLVDIHKQILGKSGINMLLHKEFVHHLVNYYEICDSVLA
>SEQF1516_EDU84076.1 molybdenum cofactor biosynthesis protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQVSTEFIPTRIAILTVSNRRGEEDDTSGHYLRDSAQEAGHHVVDKAIVKENRYAIRAQVSAWIASDDVQVVLITGGTG
LTEGDQAPEALLPLFDREVEGFGEVFRMLSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENIIAPQLDARTR
PCNFHPHLKK
>SEQF1516_EDU84077.1 molybdenum cofactor biosynthesis protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNKGFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDF
TDIIAAVRENDAIRQIAVTTNGYRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVK
VNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELLRRGWIHQLRQRSDGPAQVFCHP
DYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLFGEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGI
TQNLSYIGG
>SEQF1516_EDU84078.1 ABC-2 type transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLEVTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLL
KSPQEIRPTIDTQKALLLVRFPADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAI
GIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINP
IRHFTDITKQIYLKDASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM
>SEQF1516_EDU84079.1 glutamine ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEFKNVSKHFGPTQVLHNIDLNIAQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAG
MVFQQFYLFPHLTALENVMFGPLRVRGANKEEAEKLARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLF
DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQEFLQHVS
>SEQF1516_EDU84080.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDAVITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGAGKTTLMRMLAGLLKPDSGNATVIGFDPIKNDGALHA
VLGYMPQKFGLYEDLTVMENLNLYADLRSVTGEARKQTFARLLEFTSLGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVL
LLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLMNEGELLYQGEPKALTQTMAGRSFLMTSPHE
GNRKLLQRALKLPQVSDGMIQGKSVRLILKKEATPDDIRHADGMPEININETTPRFEDAFIDLLGGAGTSESPLGAILHT
VEGTPGETVIEAKELTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMDLKESSGKA
RQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSEAFGLKSIASHATDELPLGFKQRLALACSLMHEPD
ILFLDEPTSGVDPLTRREFWLHINSMVEKGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQSANDEQPDPTM
EQAFIQLIHDWDKEHSNE
>SEQF1516_EDU84081.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKSHPRWRLAKKILTWLFFIAVIVLLVVYAKKVDWEEVWKVIRDYNRVALLSAVGLVVVSYLIYGCYDLLARFYCGHKL
AKRQVMLVSFICYAFNLTLSTWVGGIGMRYRLYSRLGLPGSTITRIFSLSITTNWLGYILLAGIIFTAGVVELPDHWYVD
QTTLRILGIGLLMIIAVYLWFCAFAKHRHMTIKGQKLVLPSWKFALAQMLISSVNWMVMGAIIWLLLGQSVNYFFVLGVL
LVSSIAGVIVHVPAGIGVLEAVFIALLAGEHTSKGTIIAALLAYRVLYYFIPLLLALICYLLLESQAKKLRAKNEAAM
>SEQF1516_EDU84082.1 putative ATP-dependent helicase DinG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPSNFQSNILREGVFASRFPETEKPLPLKTEKCHNIGCLYSISGFLMALTAALKAQIAAWYKALQEQIPDFIPRAPQRQM
IADVAKTLAGEEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKKIIPDLKFTAAFG
RGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLKGDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASC
LNRNCYYYRECPFFVARREIQEAEVVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRL
QLDLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEHRFAMGELPDEVLEICQRLAK
LTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRALGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFH
CVGIRVSDQLERLLWRSIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVEPSIDNE
EQHIAEMAAFFREQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGDQPRYRLVELHRKRVANGERSVLVGLQSF
AEGLDLKGDMLSQVHIHKIAFPPIDSPVVITEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRL
LTKNYGKRLLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR
>SEQF1516_EDU84083.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKCLTLLIATVLSGISLTAYAAQPMSNLDSGQLRPAGTVSATGASNLSDLEDKLAEKAREQGAKGYVINSAGGNDQMFG
TATIYK
>SEQF1516_EDU84084.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTINTVVAAMALSALSFGVFAAEPVTASQAQNMNKIGVVSADGASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSG
TAVIYK
>SEQF1516_EDU84085.1 molybdopterin converting factor, subunit 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKVLFFAQVRELVGTDATEVAADFPTVEALRQHLAAQSDRWALALEDGKLLAAVNQTLVSFDHPLTDGDEVAFFPPVTG
G
>SEQF1516_EDU84086.1 putative cardiolipin synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFEDDVGKQLHAALLAAAQRGVKAEVLLDGYGSPDLSDE
FVNELTAAGVVFRYYDPRPRLFGMRTNVFRRMHRKIVVIDARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDIL
QFELENLPGQSAARRWWRRHHKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQARREVIIANAYFFPGYRFLHAL
RKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVKGGVQVFEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEAN
VIIHDRHFNQTLRDNLNGIIAADCQQVDETMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPRLAQVDPPAQPTMET
QDRVETENTGVKP
>SEQF1516_EDU84087.1 glutamine ABC transporter, glutamine-binding periplasmic protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGDKYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQ
TKNVDLALAGITITDERKKAIDFSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPN
IDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDELRDKVNGALKTLRENGTYNEIYK
KWFGTEPK
>SEQF1516_EDU84088.1 C4-type zinc finger protein, DksA/TraR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASGWANDDAVNEQINSTIEDAIARARGEIPRGESLYECEECGAPIPQARREAIPGVRLCIHCQQEKDLQKPAYTGYNRR
GSKESQLR
>SEQF1516_EDU84089.1 malate/L-lactate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAGHDSHGIGMIPSYVRSWSQGHLQINHHAKIVKEAGAA
VTLDGDRAFGQVAAHEAMALGIEKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRF
GTNPFCVVFPRKDDFPLLLDYATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPAVMQESPLGSLLTFAEHKGYALA
AMCEILGGALSGGKTTHQETLQTSPDAILNCMTTIIINPELFGAPDCSAQTEAFAEWVKASPHDDDKPILLPGEWEVNTR
RERQEQGIPLDAGSWQAICDAARQIGMPEETLQAFCQQLAS
>SEQF1516_EDU84090.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKWQQRVRVATGLSCWQIMLHLLVVALLVVGWMSKTLVHVGVGLCALYCVTVVMMLVFQRHPEQRWREVADVLEELTTTW
YFGAALIVLWLLSRVLENNFLLAIAGLAILAGPAVVSLLAKDKKLHHLTSKHRVRR
>SEQF1516_EDU84091.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDRFPRSDSIVQPRAGLQTYMAQVYGWMTVGLLLTAFVAWYAANSAAVMELLFTNRVFLIGLIIAQLALVIVLSAMIQKL
SAGVTTMLFMLYSALTGLTLSSIFIVYTAASIASTFVVTAGMFGAMSLYGYTTKRDLSGFGNMLFMALIGIVLASLVNFW
LKSEALMWAVTYIGVIVFVGLTAYDTQKLKNMGEQIDTRDASNLRKYSILCALTLYLDFINLFLMLLRIFGNRR
>SEQF1516_EDU84092.1 excinuclease ABC, B subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSGKTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEF
FPENAVEYFVSYYDYYQPEAYVPSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFDEEVERLSLFDPLTGQIVSTIPR
FTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLENNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGE
PPPTLFDYLPADGLLVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYVSATPGNYE
LEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVLVTTLTKRMAEDLTEYLEEHGERVRYLHSDI
DTVERMEIIRDLRLGEFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPS
MAKAIGETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVPMDMSPKALQQKIHELE
GLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS
>SEQF1516_EDU84093.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESYLQNSNKLDFQHETRILNGIWLITALGLVATAGLAWGAKYLEITATKYDSPPMYVAIGLLLLCMYGLIKDINKINAA
IAGVIYLFLLSLVAIVVASLVPVYAIIVVFSTAGAMFLISMLAGLLFNIDPGSHRFMIMMTLTGLALVIIVNAALMSERP
IWVISCLMIVLWSGIILHGRNKLLELAGKCHSEELWSPVRCAFTGALTLYYYFIGFFGILAAIAITLVWQRHTRFFH
>SEQF1516_EDU84094.1 endonuclease/exonuclease/phosphatase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDQTQQFSFKVLTINIHKGFTAFNRRFILPELRDAVRTVSADIVCLQEVMGAHEVHPLHVENWPDTSHYEFLADTMWSD
FAYGRNAVYPEGHHGNAVLSRYPIEHYENRDVSVDGAEKRGVLYCRIVPPMTGKAIHVMCVHLGLREAHRQAQLAMLAEW
VNELPDGEPVLVAGDFNDWRQKANHPLKVQAGLDEIFTRAHGRPARTFPVQFPLLRLDRIYVKNASASAPTALPLRTWRH
LSDHAPLSAEIHL
>SEQF1516_EDU84095.1 glycosyl transferase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDYRKIIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGGVLIALRIKGEGEAEMLGFYEAMQNHTIKLTPPAGKP
MPIVIPSYNGARKQANLTPLLAILLHKLGFPVVVHGVSEDPTRVLTETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGA
FCPPLEKQLAMRWRMGVRNSAHTLAKLATPFAEGEALRLSSVSHPEYIGRVAKFFSDIGGRALLMHGTEGEVYANPQRCP
QINLIDREEMRVLYEKQDPAGSELLPQAKDPETTAQWIQRCLAGREPIPESLKIQMACCLVATGEAATISDGLARVNQAF
>SEQF1516_EDU84096.1 catecholate siderophore receptor Fiu [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTLVVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISE
QVIKDQGATNLTDALKNVPGVGAFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGEKTHDAGRDKVKNERYGVAPSIA
FGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSAPSAGTATLNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDIND
NTTIRNTTRWSRVKQDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTASIGHDVSTGVEF
TRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYAFDTLQITRDFELNGGIRLDNYHTEYDSATA
CGGSGRGAITCPAGVAKGSPVTTVDTAKSGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTD
FKPQKANTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNITPAWQVIGGYTQQKAT
IKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGARYIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLD
FQLNVYNLFDTDYVASINKSGYRYHPGEPRTFLLTANMHF
>SEQF1516_EDU84097.1 molybdenum cofactor biosynthesis protein C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMIIDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLM
LSKVEVNLQAEPEHNRVRIETLCRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEAD
D
>SEQF1516_EDU84098.1 transcriptional regulator, TetR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQNIAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEE
AERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
NDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGLSQRSL
>SEQF1516_EDU84099.1 ABC-2 type transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFGYGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYI
DATISDNRQELIAKMQAGKIRGLVVIPVDFAEQMERANATAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQT
FEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLSTEITRTELLLCKLIPYYFLGML
AMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTLGMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAV
IRAVTYIIPARYFVSTLQSLFLAGNIPVVLVVNVLFLIASAVMFIGLTWLKTKRRLD
>SEQF1516_EDU84100.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDNGGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAM
FEYRFGGNGELSGHNLGNLMLKALDHLSVRPLEAINLIRNLLKVDAHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTP
IQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMVYIGNLGRELSLPAANLKLESKL
AIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVLEASDIPYRHDRQLLHSALEKALQALG
>SEQF1516_EDU84101.1 hypothetical protein ECH7EC4501_1403 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALMALAQARVGNTGSCEAMTAAIVTTKCGITCCFLP
>SEQF1516_EDU84102.1 molybdopterin converting factor, subunit 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLGDSVKALTLEHYPGMTEKALAEIVDEARNRWPLGLVT
VIHRIGELWPGDEIVFIGVTSAHRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW
>SEQF1516_EDU84103.1 glutamine ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFARTFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPM
AFNDLRIDPFTAAVVTIMINSGAYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKIL
>SEQF1516_EDU84104.1 oxidoreductase, 2OG-Fe(II) oxygenase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMYHIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQQVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLS
TPLFNRYQNNETYGFHVDGAVRSHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCV
TPVTRGVRVASFIWIQSMIRDDKKRAMLFELDKNIQNIQSLKSRYGENEEILSLLNLYHNLLREWSEI
>SEQF1516_EDU84105.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDCSKCNGYATMLLNMVQGSDPVNLLELHGFLEHFAYYVSFGKFNAGHQRYNAFKKFVSEISEISANDINMTIKTGQSRH
ENVISINMNDAIPRDEKGITVRIDNINGKKNNSNSSDVFIPYVNTFPDLKNKILRMKIELTEGSGFSKSLSDSQIEMHIL
RTVNSLNVGEKLNDDNLADHSIFTNEFSVIIPPSYYDATSAVNANNIVREKLFESDSKVKDIVDDMSNHDVESEKDIFVI
GGMIEKLNSLADESFNDSTDNIQTVKDLLTQLTDGMELFALRDIVAFPSTIIAKLIKSPLNSDHELVMRALDTYLCYFRN
KNLNNNAEIINFFHALFLKRPELMVAENYRFIQFIDLLFENGNVEEKNLAFDLYHNYLSLSEIKQFVTEEIKLNFNEQQG
LLDKDNKCYILLSSDNSGRVMRLSHQALISMLEPEVKKKTIWNNYSIYPSLQDTHEVVRDDPETICMRAFPLFAKGWEYA
QKNKKHQLILNALGFKGYIRDIFMSAIMRKTDFVLECNNQPTELNSSFSSLMNDSDQWQQHTLKDKHYANLLTMLDLNDA
SESDKSKIFFCLSAVFANISHSNVFNGIPDASKTLKRYAFALLAKAHSLDESMISNQTFNTYKTVLLDFNNLSNEEANQL
RISSLYRDMVRYAQYRFSKVLSEWTPDAWL
>SEQF1516_EDU84106.1 transporter, small conductance mechanosensitive ion channel (MscS) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQKKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEP
VPKIVPPTLVEEQTVLQKVTEFSRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL
PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQILSDNLNAGSRTIAFQQSLFLNAFALIEFFKAVL
RLIFCPNVAELRPFTIQDESARYWSRRLSWLGSLIGYGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKE
ITQHLLNFAEHSLAFFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSGMFSRWLAK
TITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFDFWNWLQNGAGQKTVDILIRIALILFFSAVG
WTVLASLIENRLASDIHGRPLPSARTRTLLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVK
DIITGVFIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGIGSVVANYDVDRHEDAD
KANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLSNTAFTLRVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTY
QVLPAPGATPAEPLPPGEPTL
>SEQF1516_EDU84107.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAQKPGLHPRNRHHSRYDLATLCQVNPELKQFLTLTPAGEQSVDFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPV
PGRADYIHHLADLLAEASGTIPANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLR
RQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSECKRRNLGLNKDDALNFGGQQQELWCEGGEVTFIKKMIEES
KGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVVKKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR
>SEQF1516_EDU84108.1 putative ATP-dependent RNA helicase RhlE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFDSLGLSPDILRAVAEQGYREPTPIQQQAIPAVLEGRDLMASAQTGTGKTAGFTLPLLQHLITRQPHAKGRRPVRALI
LTPTRELAAQIGENVRDYSKYLNIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQVEILVLDEADR
MLDMGFIHDIRRVLTKLPAKRQNLLFSATFSDDIKALAEKLLHNPLEIEVARRNTASDQVTQHVHFVDKKRKRELLSHMI
GKGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIHGNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNY
ELPNVPEDYVHRIGRTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAIPGYEPDPSIKAEPIQNGRQQRGGGGRG
QGGGGRGQQQPRRGEGGAKSASAKPAEKPSRRLGDAKPAGEQQRRRRPRKPAAAQ
>SEQF1516_EDU84109.1 cyclic diguanylate phosphodiesterase (EAL) domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKAQRIIKTYRRNRMIVCTICALVTLASTLSVRFISQRNLNQQRVVQFANHAVEELDKVLLPLQAGSEVLLPLIGLPCS
VAHLPLRKQAAKLQTVRSIGLVQDGTLYCSSIFGYRNVPVVDILAELPAPQPLLRLTTDRVLIKGSPVLIQWTPAASSSN
AGVMEMINIDLLTAMLLEPQLPQISSASLTVDKRHLLYGNGLVDSLPQPEDNENYQVSSQRFSFTINVNGPGAPALAWHY
LPTQLPLAVLLSLLVGYIAWLATAYRMSFSREINLGLAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGWISPDVFI
PIAEEHHLIVPLTRYVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLNQYWFSAHPIQQLILEITERDALLDVD
YRIARELHRKNVKLAIDDFGTGNSSFSWLETLRPDVLKIDKSFTAAIGSDAVNSTVTDIIIALGQRLNIELVAEGVETQE
QAKYLRRHGVHILQGYLYAQPMPLRDFPKWLAGSQPPPARHNGHITPIMPLR
>SEQF1516_EDU84110.1 putative homoserine/threonine efflux protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGYLAACGVFIGDAVLMFLAWAGMATLIKTTPILFNIVR
YLGAFYLLYLGSKILYATLKGKNNEAKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTL
ELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS
>SEQF1516_EDU84111.1 L-serine ammonia-lyase 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDSVTRVAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDI
DSIPGFIRDVEERERLLLAQGRHEVDFPRDNGMRFHNGNLPLHENGMQIHAYNGDEVVYSKTYYSIGGGFIVDEEHFGQD
TANEVSVPYPFKSATELLAYCNETGYSLSGLAMQNELALHSKKEIDEYFAHVWQTMQACIDRGMNTEGVLPGPLRVPRRA
SALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENAAGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFMAAG
AIGALYKMNASISGAEVGCQGEVGVACSMAAAGLAELLGGSPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPCIERNAIAS
VKAINAARMALRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIKVQCD
>SEQF1516_EDU84112.1 membrane protein, TerC family/CBS/transporter associated domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMD
FSFSGRDLIMLFGGIFLLFKATTELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIIIEVFNQIARRNFIRHQS
TLPLRARTADAILRLMGGKRQANVQHDADNPMPMPIPEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVD
EIREQLLSSPHSLFPVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRARGSFVIVTN
EFGVVQGLVTPLDVLEAIAGEFPDADETPEIITDGDGWLVKGGTDLHALQQALDVEHLADDDDIATVAGLVISANGHIPR
VGDVIDVGPLHITIIEANDYRVDLVRIVKEQPAHDEDE
>SEQF1516_EDU84113.1 diguanylate cyclase (GGDEF) domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGTQKLKAQSFFIFSLLLTLILFCITTLYNENTNVKLIPQMNYLMVVVALFFLNAVIFLFMLMKYFTNKQILPTLILSLA
FLSGLIYLVETIVIIHKPINGSTLIQTKSNDVSIFYIFRQLSFICLTSLALFCYGKDNILDNNKKKTGILLLALIPFLVF
PLLAHNLSSYNADYSLYVVDYCPDNHTATWGINYTKILVCLWAFLLFFIIMRTRLASELWPLIALLCLASLCCNLLLLTL
DEYNYTIWYISRGIEVSSKLFVVSFLIYNIFQELQLSSKLAVHDVLTNIYNRRYFFNSVESLLSRPVVKDFCVMLVDINQ
FKRINAQWGHRVGDKVLVSIVDIIQQSIRPDDILARLEGEVFGLLFTELNSAQAKIIAERMRKNVELLTGFSNRYDVPEQ
MTISIGTVFSTGDTRNISLVMTEADKALREAKSEGGNKVIIHHI
>SEQF1516_EDU84114.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGILSWIIFGLIAGILAKWIMPGKDGGGFFMTILLGIVGAVVGGWISTLFGFGKVDGFNFGSFVVAVIGAIVVLFIYRKI
KS
>SEQF1516_EDU84115.1 oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIELGLTLIDTAEMYADGGAEKVVGEALTGLREKVFLVSK
VYPWNAGGQKAINACEASLRRLNTDYLDLYLLHWSGSFAFEETVAVMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHAHNISAAQVLLAWVISHQGVMAI
PKAATIAHVQQNAAVLEVELSSAELAMLDKAYPAPKGKTALDMV
>SEQF1516_EDU84116.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFPWIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSF
LNWKSLVAIAVGVIVSWLGGRGVTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIATGLVSLIVGKQ
>SEQF1516_EDU84117.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQIPQNYIHTRSTPFWNKQTAPAGIFERHLDKGTRPGVYPRLSVMHGAVKYLGYADEHSAEPDQVILIEAGQFAVFPPE
KWHNIEAMTDDTYFNIDFFVAPEVLMEGAQQRKVIHNGK
>SEQF1516_EDU84118.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVFYWRLCCPGSIKMKKTTIIMMGVAIIVVLGTELGWW
>SEQF1516_EDU84119.1 aminodeoxychorismate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYSRFDIVVADPICTLTTLGKETVVSESEKRTTTTDDPL
QVLQQVLDRADIRPTHNEDLPFQGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDV
NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRRVQEYLHSGDCYQVNLAQRFHATYSGDEWQAFLQLNQANRAP
FSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGTLPRLPAPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVA
GSVKVPELFVVEPFPAVHHLVSTITAQLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCGSIGYLSFC
GNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQLEK
>SEQF1516_EDU84120.1 MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKLKLLALGVLIATSAGVAHAEGKFSLGAGVGVVEHPYKDYDTDVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSI
TAYWSPLYFKAKDSGDHQMRHLDDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGI
GVQWNSENQNEYYYGVSRKESARSGLRGYNSNDSWSPYLELSASYNFLGDWSVYGTARYTRLSDEVTDSPIVDKSWTGLI
STGITYKF
>SEQF1516_EDU84121.1 inner membrane transport protein yeaN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAYSLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMER
SLFAALLLICAGIAIRSLPSPYLLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLA
LNGFGWQGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTLFLGINSLVYYVIIGWLPAILIS
HGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQRGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGL
TFIGLRASSAHQAAALSGMAQSVGYLLAACGPPLMGKIHDANGDWSVPLMGVAILSLLMAIFGLCAGRDKEIR
>SEQF1516_EDU84122.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHKTRIMNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLEQTLNVVLLHRTTRRVTITEEGERIYEWAQ
RILQDVGQMMDELSDVRQVPQGMLRIISSFGFGRQVVAPALSALAKAYPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIA
PNLIARKLATNYRILCASPEFIAQHGAPKHLTDLSALPCLVIKERDHPFGVWQLRNKEGHHAIKVTGPLSSNHGEIVHQW
CLDGQGIALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVSRLATSAKVRITVEFLRQYFAEHYPNFSLEHA
>SEQF1516_EDU84123.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIQCKRVYDPAEQSDGYRVLVDRLWPRGIKKTDLALDEWDKEITPSTELRKAFHGEVVDFATFREQYLAELAQHEQEGK
RLADIAKKQPLTLLYSAKNTTQNHALVLADWLRSL
>SEQF1516_EDU84124.1 aldose 1-epimerase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQGAHLLSWKPAGEEEVLWLSNNTPFKNGVAIRGGVPVC
WPWFGPAAQQGLPAHGFARNLPWTLKSHREDANGVALTFELTQSEETKKFWLHDFTLLAHFRVDKNCEIDLEAHGEFETT
SALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKEDVLTDGIQTFPDRTDRVYLNPQDCSVINDEALNRIIAVGHQHHLNVV
GWNPGPALSVSMGDMPDDGYKTFVCVETAYASEMQKVTKEKPAHLAQSIRVAKR
>SEQF1516_EDU84125.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIISFVLPCLLVLAGCSTPSQPEAPKPPQIGMANPASVYCQQKGGTLIPVQTAQGVSNNCKLPGGETIDEWALWRLDHP
AGEK
>SEQF1516_EDU84126.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFAGLPSLTHEQQQKAVERIQELMAQGMSSGQAIALVAEELRANHSGERIVARFEDEDE
>SEQF1516_EDU84127.1 endoribonuclease L-PSP family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIVRIDAEARWSDVVIHNNTLYYTGVPENLDADAFEQTANTLAQIDAVLEKQGSNKSSILDATIFLADKNDFAAMNKAW
DAWVVAGHAPVRCTVQAGLMNPKYKVEIKIVAAV
>SEQF1516_EDU84128.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPAVIDKALDFIGAMDVSAPTPSSMNESTAKGIFKYLKELGVPASAADITARADQEGWNPGFTEKMVGWAKKMETGERSV
IKNPEYFSTYMQEELKALV
>SEQF1516_EDU84129.1 glycoprotease family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQDILTTSGTSLTDINALAYGRGPGSFTGVRIGIGIAQG
LALGAELPMIGVSTLMTMAQGAWRKNGATRVLSAIDARMGEVYWAEYQRDENGIWHGEETEAVLKPELVHERMQQLSGEW
VTVGTGWQAWPDLGKESGLVLRDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYLRNNVAWKKLPGKE
>SEQF1516_EDU84130.1 transporter, betaine/carnitine/choline transporter (BCCT) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMSNVKKKDVPLISISLVAILFIAAALSLFPQQSADAANAIYTFVTRTLGSAVQVLVLLAMGLVIYLATSKYGNIRLGEG
KPEYSTLSWLFMFICAGLGSSTLYWGVAEWAYYYQTPGLNIAPRSQQALEFSVPYSFFHWGISAWATYTLASLIMAYHFH
VRKNKGLSLSGIIAAITGVRPQGPWGKLVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPDNFTVQAFVILLSGGIF
CLSSWIGINNGLQRLSKMVGWGAFLLPLLVLIVGPTEFITNSIINAIGLTTQNFLQMSLFTDPLGDGSFTRNWTVFYWLW
WISYTPGVAMFVTRVSRGRKIKEVIWGLILGSTVGCWFFFGVMESYAIHQFINGVINVPQVLETLGGETAVQQVLMSLPA
GKLFLAAYLGVMIIFLASHMDAVAYTMAATSTRNLQEGDDPDRGLRLFWCVVITLIPLSILFTGASLETMKTTVVLTALP
FLVILLVKVGGFIRWLKQDYADIPAHQVEHYLPQTPVEALEKTPVLPAGTVFKGDN
>SEQF1516_EDU84131.1 PTS system, mannose-specific IIAB component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAETLIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRI
VVDKEHYEVIAGVNIPMLVETLMARDDDPSFDELVALAVETGREGVKALKAKPVEKAAPAPAAAAPKAAPTPAKPMGPND
YMVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTAHVVDVAKMIRVYNNPKYAGERV
MLLFTNPTDVERLVEGGVKITSVNVGGMAFRQGKTQVNNAVSVDEKDIEAFKKLNARGIELEVRKVSTDPKLKMMDLISK
IDK
>SEQF1516_EDU84132.1 tartrate dehydrogenase/decarboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKTMRIAAIPGDGIGKEVLPEGIRVLQAAAERWGFALSFEQMEWASCEYYSHHGKMMPDDWHEQLSRFDAIYFGAVGWP
DTVPDHISLWGSLLKFRREFDQYVNLRPVRLFPGVPCPLAGKQPGDIDFYVVRENTEGEYSSLGGRVNEGTEHEVVIQES
VFTRRGVDRILRYAFELAQSRPRKTLTSATKSNGLAISMPYWDERVEAMAENYPEIRWDKQHIDILCARFVMQPERFDVV
VASNLFGDILSDLGPACTGTIGIAPSANLNPERTFPSLFEPVHGSAPDIYGKNIANPIATIWAGAMMLDFLGNGDERFQQ
AHNGILAAIEEVIAHGPKTPDMKGSATTPQVADAICKIILR
>SEQF1516_EDU84133.1 YbaK/prolyl-tRNA synthetase-associated domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEMAKGSVTHQRLIALLSQEGADFRVVTHEAVGKCEAVSEIRGTALGQGAKALVCKVKGNGVNQHVLAILAADQQADLS
QLASHIGGLRASLASPAEVDELTGCVFGAIPPFSFHPKLKLVADPLLFERFDEIAFNAGMLDKSVILKTADYLRIAQPEL
VNFRRTA
>SEQF1516_EDU84134.1 serine kinase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLMAIGEPVMVDTAQEPRLSRLFSNRVIARYPAFEEFYG
MEDAIEQIVSYLKHAAQGLEEKKQILYLLGPVGGGKSSLAERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQI
LEKEYGIPRRYLGTIMSPWAAKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDENNQDISALVGKVDIRKLEHYAQN
DPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLLTATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAF
LDRVYIVKVPYCLRISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFSILSRLKEPENSSIYSKMRVYDGESLKDTDPKA
KSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHVEVAANPVHLFYVLEQQIEREQFPQEQAERYLEFLKGYLIPKYA
EFIGKEIQTAYLESYSEYGQNIFDRYVTYADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFV
LRARANNSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKGYTRKQVRLLCEWYLRV
RKSS
>SEQF1516_EDU84135.1 Rieske 2Fe-2S domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNLSPDFVLPENFCANPQEAWTIPARFYTDQNAFEHEKENVFAKSWICVAHSSELANANDYVTREIIGESIVLVRGRDK
VLRAFYNVCPHRGHQLLSGEGKAKNVITCPYHAWAFKLDGNLAHARNCENVANFDSDKAQLVPVRLEEYAGFVFINMDPN
ATSVEDQLPGLGAKVLEACPEVHDLKLAARFTTRTPANWKNIVDNYLECYHCGPAHPGFSDSVQVDRYWHTMHGNWTLQY
GFAKPSEQSFKFEEGTDAAFHGFWLWPCTMLNVTPIKGMMTVIYEFPVDSETTLQNYDIYFTNEELTDEQKSLIEWYRDV
FRPEDLRLVESVQKGLKSRGYRGQGRIMADSSGSGISEHGIAHFHNLLAQVFKD
>SEQF1516_EDU84136.1 hypothetical protein ECH7EC4501_3020 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSSKMEKINGQSARYNQIVQLRKKTRVANQRANTTAWLCLFI
>SEQF1516_EDU84137.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVTDVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGND
HFVQNDRIERPQGGGGGSGSGQGQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGV
PANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAELRAKIERVPFIDTFDLRYKNYE
KRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILLYLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSA
LKLMDEVVKERYNPAQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHLQSTFDNFA
MQHIRDQDDIYPVFRELFHKQNATAKD
>SEQF1516_EDU84138.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDDFAPDGQLAKAIPGFKPREPQRQMAVAVTQAIEKGQPLVVEAGTGTGKTYAYLAPALRAKKKVIISTGSKALQDQLY
SRDLPTVSKALKYTGNVALLKGRSNYLCLERLEQQALAGGDLPVQILSDVILLRSWSNQTVDGDISTCVSVAEDSQAWPL
VTSTNDNCLGSDCPMYKDCFVVKARKKAMDADVVVVNHHLFLADMVVKESGFGELIPEADVMIFDEAHQLPDIASQYFGQ
SLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLAQSAQDFRLQLGEPGYRGNLRELLANPQIQRAFLLLDDTLELCYD
VAKLSLGRSALLDAAFERATLYRTRLKRLKEINQPGYSYWYECTSRHFTLALTPLSVADKFKELMAQKPGSWIFTSATLS
VNDDLHHFTSRLGIEQAESLLLPSPFDYSRQALLCVPRNLPQTNQPGSARQLAAMLRPIIEANNGRCFMLCTSHAMMRDL
AEQFRATMTLPVLLQGETSKGQLLQQFVSAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLR
GGDPFDEVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIARAVRFLAIPSSR
>SEQF1516_EDU84139.1 hypothetical protein ECH7EC4501_3021 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFIYIVSFIDKIEIIKINNELAEASTVISYSLVDLCITDQYYR
>SEQF1516_EDU84140.1 oxidoreductase, FAD/NAD-binding/iron-sulfur cluster binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDYQMFEVQVSQVEPLTEQVKRFTPVATDGKPLPAFTGGSHIIVQMSDGDNQYSNAYSLLSSPHNTSSYQIAVRLEENS
RGGSRFLHQQVKVGDRLTISTPNNLFALIPSARKHLFIAGGIGIPPFLSHMAELQHSDVDWQLHYCSRNPESCAFRDELV
QHPQAEKVHLHQSSTGTRLELARLLADIEPGTHVYTCGPEALIEAVRSEAARLDIAADTLHFEQFAIEDKTGDAFTLVLA
RSGKEFVVPEEMTILQVIENNKAAKVECLCREGVCGTCETAILEGEADHRDQYFSDEERASQQSMLICCSRAKGKRLVLD
L
>SEQF1516_EDU84141.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLNGYEPDRHHEAAVAFCIHAGTDELTSPVHQHRKGQLILALHGAITCTVENALWMVPPQYAVWIPGGVEHSNQVTANA
ELCFLFIEPSAVTMPTTCYTLKISPLCRELILTLANRTTTQRAEPMTRRLIQVLFDELPQQPQQQLHLPVSSHPKIRAMV
EMMAKEPVEWGALGQWAGFFAMSERNLARLIVKETGLSFRQWRQQLQLIMALQGLVKGDTVQKVAHTLGYDSTTAFITMF
KKGLGQTPGRYIAGLTTVSPQSAKPDPWQ
>SEQF1516_EDU84142.1 outer membrane protein Slp [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVQKNVIKGILAGTFALMLSGCVTVPDAIKGSSPTPQQDLVRVMSAPQLYVGQEARFGGKVVAVQNQQGKTRLEIATVP
LDSGARPTLGEPSRGRIYADVNGFLDPVDFRGQLVTVVGPITGAVDGKIGNTPYKFMVMQATGYKRWHLTQQVIMPPQPI
DPWFYGGRGWPYGHGGWGWYNPGPARVQTVVTE
>SEQF1516_EDU84143.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKATYTVTVTNNSNGVSVDYETETPMTLLVPEVAAEVIKDLVNTVRSYDTENEHDVCGW
>SEQF1516_EDU84144.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHANNNVKTAISRGYAMNDQMFVETLIITSSFFAIAVVLVLSVLLIERTG
>SEQF1516_EDU84145.1 ribonuclease D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNYQMITTDDALASLCEAVRAFPAIALDTEFVRTRTYYPQLGLIQLFDGEHLALIDPLGITDWSPLKAILRDPSITKFLH
AGSEDLEVFLNVFGELPQPLIDTQILAAFCGRPMSWGFASMVEEYSGVTLDKSESRTDWLARPLTERQCEYAAADVWYLL
PITAKLMVETEASGWLPAALDECRLMQMRRQEVVAPEDAWRDITNAWQLRTRQLACLQLLADWRLRKARERDLAVNFVVR
EEHLWSVARYMPGSLGELDSLGLSGSEIRFHGKTLLALVEKAQTLPEEALPQPMLNLMDMPGYRKAFKAIKSLITDVSET
HKISAELLASRRQINQLLNWHWKLKPQNNLPELISGWRGELMAEALHNLLQEYPQ
>SEQF1516_EDU84146.1 hypothetical protein ECH7EC4501_3035 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIILWDLQHPFPSFGECAENGLFQPFQGTPDNLLFKYHLLVTF
>SEQF1516_EDU84147.1 diguanylate cyclase (GGDEF) domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQKADSSFLYDKYQNQSIAAHVMRALAAEQSEVSPEQR
RAICEAFESANNTHGLNLTAHKYPGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDL
NDRYVYFYEPVNVEYFAMNNWSILQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQNVMSLLTPVYVAGQLKGIVLLDI
NKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIIINQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWI
LTALILLNMVRMHFRLYQNVSRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKLINDTLGHQEGDL
AITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRLQHIAPQKEIGFSSGIYAMKENDTLHDAYKA
SDERLYVNKQNKNSRS
>SEQF1516_EDU84148.1 long-chain-fatty-acid--CoA ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTACISFGVAMTTNTHFRGEELKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVNMGEVMTFRKLEERS
RAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVVNVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKV
VDKTAVQHVILTRMGDQLSTAKGTLVNFVVKYIKRLVPKYHLPDAISFRSALHNGYRMQYVKPELVPEDLAFLQYTGGTT
GVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELGGQNLLITNPRDIPGLVKELAKY
PFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGGMPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSG
SIGLPVPSTEAKLVDDDDNEVSPGQPGELCVRGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFLRIVDRKKDMI
LVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDPSLTEESLVTFCRRQLTGYKVPKLVEFRDELPK
SNVGKILRRELRDEARGKVDNKA
>SEQF1516_EDU84149.1 hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQPGLLLTQRSIHLRKHAGQVAFPGGAVDDTDASVIAAA
LREAEEEVAIPPSAVEVIGVLPPVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDS
HRVWLSWYEQYFVWGMTAGIIRELALQIGVKP
>SEQF1516_EDU84150.1 IS629 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU84151.1 ABC transporter, quaternary amine uptake (QAT) family, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTYLRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQLWPQTIWMLVGVGCAWLTACFIPAKKGSIFALILAQF
VFVLLVWGAGKAATQLAQNGSALARTSLGSGFWLASALALLACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDL
SLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNVIQTVPSVALFGLLIAPLAGLVT
AFPWLGKLGIAGTGMTPALIALVLYALLPLVRGVVVGLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVM
VQTVGMAVIAALIGAGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLIDALFDLLIALLKVKRND
>SEQF1516_EDU84152.1 phage N-6-adenine-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIKSNTPAHDKDCWQTPLWLFDALDIEFGFWLDSAASDKNALCAHWLTEADDALNSEWISHGAIWNNPPYSNIRPWVEK
AAEQCIQQRQTVVMLVPEDMSVGWFSKALESVDEVRIITDGRINFIEPSTGLEKKGNSKGSMLLIWRPFISPRRMFTTVS
KAALMAIGLGVRRAA
>SEQF1516_EDU84153.1 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYCHAKLKNISQHTVISAHLFLPDYSPMNRDSFYPAIACFPLLLMLAGCAPMHETRQALSQQTPAAQVDTALPTALKNGW
PDSQWWLEYHDNQLTSLINNALQNAPDMQVAEQRIQLAEAQAKAVATQDGPQIDFSADMERQKMSAEGLMGPFALNDPAA
GTTGPWYTNGTFGLTAGWHLDIWGKNRAEVTARLGTVKARAAEREQTRQLLAGSVARLYWEWQTQAALNTVLQQIEKEQN
TIIATDRQLYQNGITSSVEGVETDINASKTRQQLNDVAGKMKIIEARLIALTNHQTKSLTLKPVALPKVASQLPDELGYS
LLARRADLQAAHWYVESSLSTIDAAKAAFYPDINLMAFLQQDALHLSDLFRHSAQQMGVTAGLTLPIFDSGRLNANLDIA
KAESNLSIASYNKAVVEAVNDVARAASQVQTLAEKNQHQAQIERDALRVVGLAQARFNAGIIAGSRVSEARIPALRERAN
GLLLQGQWLDASIQLTGALGGGYKR
>SEQF1516_EDU84154.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTSETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU84155.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLFFCKEMPPYKDVEQKTTTIIIFLILTALKTTSYHHDDDDDKITKMRLFPRPPAPCSGPPHQEDPQNDNGYHLQQNPV
SSTIAPDWRL
>SEQF1516_EDU84156.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISDKLITLVKSLCVLVGISFLVMLVAIFFSTAWRVLTLSGLVG
>SEQF1516_EDU84157.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLNTLISQYGYAALVIGSLAEGETVTLLGGLAAHQGLLKFPLVVLSVALGGMIGDQVLYLCGRRFGGKLLRRFSKHQDK
IERAQKLIQRHPYLFVIGTRFMYGFRVIGPTLIGASQLPPKIFLPLNILGAFAWALIFTTIGYAGGQVIAPWLHNLDQHL
KHWVWLILVVVLVVGVRWWLKRRGKKKPDNQA
>SEQF1516_EDU84158.1 exonuclease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEIHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAW
GKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQY
SMWVTRKDAWYFANYDPRMKREGLHYVVIERNEKYMASFDEMVPEFIEKMDEALAEIGFVYGEQW
>SEQF1516_EDU84159.1 replication protein P [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIAAQMVNFDREQMRRIANNMPEQYDEKPQVQQVAQIINGVFSQLLATFPASLANRDQNEVNEIRRQWVLAFRENGIT
SMEQVNAGMRVARRQNRPFLPSPGQFVAWCREEASVIAGLPNVSELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNL
YQNMRANALTDAELRRKAADELTCMTARINRGEAIPEPVKQLPVMGGRPLNRVQALAKIAEIKAKFGLKGASV
>SEQF1516_EDU84160.1 penicillin-binding protein 7 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIMPKFRVSLFSLALMLAVPLAPQAVAKTAAATTASQPEIASGSAMIVDLNTNKVIYSNHPDLVRPIASISKLMTAMVV
LDARLPLDEKLKVDISQTPEMKGVYSRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMN
NTRFVEPTGLSVHNVSTARDLTKLLIASKQYPLIGQLSTTREDMATFSNPTYTLPFRNTNHLVYRDNWNIQLTKTGFTNA
AGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTWIETGKVMPVPAAALSYKKQKAAQMAAAGQTAQND
>SEQF1516_EDU84161.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKPQRTDGGHRLFNDADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRTWIKERG
QDYPAQTLTTHLFIPLRRRLQYQQPTLQALLAILDGVLINYIAICLASARKKQGKDALVVGWNIQDTTRLWLEGWIASQQ
GWRIDVLAHSLNQLRPELFEGRTLLVWCGENRTSAQQQQLTSWQEQGHDIFPLGI
>SEQF1516_EDU84162.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDGELKNMKLNINQLAALSGLHRQTVAARMADVPLAPGSNEKKKLYLLTDLITSLLEKPPSSEDEDMDPHARKAWYQSER
ERLKFQHETVQLVPVSDVRRSFSVVVKAIVQVLETWPDRLERDRGWTASQLNEVQIVVDEIRDTLEKAVIDCCDEADM
>SEQF1516_EDU84163.1 hypothetical protein ECH7EC4501_1692 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNIKKYIIDYDWKASIEIEIDHDVMTEEKLHQINNFWSDSEYRLNKHGSVLNAVLIMLAQHALLIAISSDLNAYGVVCE
FDWNDGNGQEGWPSMDGSEGIRITDIDTSGIFDSDDMTIKAA
>SEQF1516_EDU84164.1 Int protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNASYPTGVENHGGSLRIWFHYNGKRVRENLGVPDTAKNRKIAGELRTSVCFAIRMGSFDYAAQFPNSPNLKHFGLGKR
EITVKALSEKWLDLKKIEICANALNRYQSVIKNMLPMLGEKKLVSSITKEDLLFVRRDLLTGYQKLSNGKTSSIKGRSVV
TVNYYMTTIAGMFQFATDNGYTSGNPFNGLAPLKKSKVKPDPLTRDEFIRFIEACRHQQTKNLWILAVYTGIRHGELVSL
AWEDIDLKARTITIRRNYTKLGEFTPPKTDAGTGRTIHLVQPAIDALKSQAEMTMLGKQHSVEVKQREYGRTAVHKCTFV
FSPQVTKQQQLSGPHYKVDSIRESWTSILKRAGLRHRKSYQSRHTYACWSLAAGANPSFIASQMGHTNAQMVFNVYGAWM
KDNNHEQIELLNKRLSESVPCMPHKKAG
>SEQF1516_EDU84165.1 ABC transporter, quaternary amine uptake (QAT) family, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKMLRDPLFWLIALFVALIFWLPYSQPLFAALFPQLPRPVYQQESFAALALAHFWLVGISSLFAVIIGTGAGIAVTRPWG
AEFRPLVETIAAVGQTFPPVAVLAIAVPVIGFGLQPAIIALILYGVLPVLQATLAGLGAIDASVTEVAKGMGMSRGQRLR
KVELPLAAPVILAGVRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGALLVALAAIIADRLFERLVQALSQ
HAK
>SEQF1516_EDU84166.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQMEKITTGVSYTTSAVGTGYWFLQLLDRVSPSQWAAIGVLGSLLFGLLTYLTNLYFKIKEDRRKAARGE
>SEQF1516_EDU84167.1 antitermination protein N [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTIVWKESKGTAKSRYKARRAELIAERRSNEALARKIALKLSGCVRADKAASLGSLRCKKADECSGSICLPNVAIYAAG
YRKSKQLTAR
>SEQF1516_EDU84168.1 D-lactate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSMTTTDNKAFLNELARLVGHSHLLTDPAKTARYRKGFRSGHGDALAVVFPGSLLELWRVLKACVTADKIILMQAANTG
LTEGSTPNGNDYDRDIVIISTLRLDKLHVLGKGEQVLAYPGTTLYSLEKALKPLGREPHSVIGSSCIGASVIGGICNNSG
GSLVQRGPAYTEMSLFARINEDGKLTLVNHLGIDLGETPEQILSKLDDDRIKDDDVRHDGRHAHDYDYVHRVRDIEADTP
ARYNADPDRLFESSGCAGKLAVFAVRLDTFEAEKNQQVFYIGTNQPEVLTEIRRHILANFENLPVAGEYMHRDIYDIAEK
YGKDTFLMIDKLGTDKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHLLLKMAGDG
VGEAKSWLVDYFKQAEGDFFVCTPEEGSKAFLHRFAAAGAAIRYQAVHSDEVEDILALDIALRRNDTEWYEHLPPEIDSQ
LVHKLYYGHFMCYVFHQDYIVKKGVDVHALKEQMLELLQQRGAQYPAEHNVGHLYKAPETLQKFYRENDPTNSMNPGIGK
TSKRKNWQEVE
>SEQF1516_EDU84169.1 hypothetical protein ECH7EC4501_1712 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFSSFVARRGSENGAKTVVCHKHDGERKRMLSLLSEFSKYSLAELSYKALF
>SEQF1516_EDU84170.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDKQEVSLAHINDVLESKNYIETNADGVVTIGTDNNGYEVFNFVFLNSTPVIGHMNGEIAVAGMQRTKVASVTLSKQKA
FDFYQSLKSMFEE
>SEQF1516_EDU84171.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPQQENALRSIARQANSEIKKARQQFPDKNVDDICRSVLKKHRETVTLMGFTPTHLSLAIGMLNGVFKER
>SEQF1516_EDU84172.1 YjhS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFKHYDVVRAASPSDLADALAQKIREGWQPYGGPFSSYTDDGAALIQAIVAEGDVSTPVVVKLTGGEGAVISATSDPGY
YFVVVLAGQSNGMSYGEGLPLPETYDRPDPRIKQLARRSTVTPGGVACKYNDIIPADHCLHDVQDMSRLNHPKADLSKGQ
YGTVGQGLHIAKKLLPFIPANAGILLVPCCRGGSAFTTGADGTYSDASGASENSTRWGVDKPLYKDLIGRTKAALKKNPK
NVLFAVVWMQGEFDFGGTPANHAAQFGALVDKFRADLADMAGQCVGGSADGVPWICGDTTYFWKQKNESSYQTVYGSYKN
KTEKNIHFVPFMTDENGVNVPTNKPEEDPDIPGIGYYGSKWRDSSATWTSQDRASHFSAWARRGIISDRLATAILRHAGR
VALNAGVSSTVSEVRPSSPSGAEVTGVTTLLSYLASESEGSLKAQGWSASGGRAEVVSDAEGTGGKAVKLTKEAGKSSWV
LEYAAGNGAALLQKGGQIRCRFKVSGALAANQYVMAFYWPVSSLPQGVALTGDGGNNLLAAFYIQTDAKDLNVMYHNAKV
ATNNLKLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTLTQSPVSAFAADKLHVTDITRNATYPVLIDSIAVE
VNSTDTAA
>SEQF1516_EDU84173.1 lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRKLRYGLSAAVLALIAAGASAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGATRVDGKPVIPGMKLSKEKCDRVNAI
ERDKALAWVEKNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYRRINAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
VSRRDQESALACWGIDR
>SEQF1516_EDU84174.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEINYQALREKAEKATKGSYIVGHTSVNQHGNLTGVFVCQKWKGEPGGVIAECHVNCLVETDVQAYANAEFIAAFNPNV
ALALLDERERNQQYIKRRDQENEEIALTVGKLRVELEAAKSKLNEQREYYEGVIADGSKRIAELEKQCAEWERKALSNFE
ECAAMAERIEEMQTKSAPDSFGIIGENIRTQDNRITSDPMFCVYQKREIAVDADYDHDRIVWVDEDGNEANKRHSRRLEL
LHENFREPPEKWRRVAVKDIDEFVTCCFTEQGCKDYLAVNGHNLRLPFIYVKSGFRNAEYIGIRNWLAGIRIKGE
>SEQF1516_EDU84175.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHVWGLFSHPDREMQVINRENETISHHYTHHVLLMAAIPVICAFIGTTQIGWNFGDGTILKLSWFTGLALAVLFYGVML
AGVAVMGRVIWWMARNYPQRPSLAHCMVFAGYVATPLFLSGLVALYPLVWLCALVGTVALFYTGYLLYLGIPSFLNINKE
EGLSFSSSTLAIGVLVLEVLLALTVILWGYGYRLF
>SEQF1516_EDU84176.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFLNQLMLYFCTVVCVLYLLSGGYRAMRDFWRRQIDKRAAEKISASQSAGSKPEEPLI
>SEQF1516_EDU84177.1 putative excisionase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQGKEYRHYAVEGDPGHYSECLYNIEEIMRWIENQKQPGAKNASSG
>SEQF1516_EDU84178.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKILVGMIRRTSAASGMVNRMSDAARTPYPGQWFYA
>SEQF1516_EDU84179.1 replication protein O [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNTAKILNFGRGNFAEQERNVADLDDGYARLSNMLIEAYSGADLTKRQFKVLLAILRKTYGWNKPMDRITDSQLSEITK
LPVKRCNEAKLELVRMNIIKQQGGMFGPNKNISEWCIPQNEGGSPKMRDIPQNEGKSPKTRDKTSLKLGDCYPSKQGDTK
DTITKEKRKDYSSENSGESSDQPENDLSVVKPDAAIQSGSKWGTAEDLTAAEWMFDMVKTIAPSARKPNFAGWANDIRLM
RERDGRNHRDMCVLFRWACQDNFWSGNVLSPAKLRDKWTQLEINRNKQQAGVTASKPKLDLTNTDWIYGVDL
>SEQF1516_EDU84180.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRVLCVVIIVLAVGYGALWLATNHYRDNALTYKAQRDKKARELEQANATITDMQVRQRDVAALDAKYSRELADARAENE
TLRADVAAGRKRLRINATCSGTVREATGTSGVDNATGPRLADTAERDYFILRERLMTMQKQLEGAQDYIRTQCLN
>SEQF1516_EDU84181.1 putative 3-oxoacyl-[acyl-carrier-protein] reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSHGVRAEIVQLDLGNLPEGAQALEKLIQRLGR
IDVLVNNAGAMTKVPFLDMAFDEWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHAL
GGLTKAMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIASLVAWLCSEGANYTTGQSLIVD
GGFMLANPQFNPE
>SEQF1516_EDU84182.1 Ant protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMMAVPFHGNSLYVVNHNGEPYVPMKPVVAGMGLAWQSQLAKLRQRFASTITEIVMVAEDGKQRNMVSMPLRKLAGWLQ
TINPNKVKPEIRDKVIRYQEECDDVLYEYWTKGFVVNPRKMSVMEELNQACADMKRDKNIASVFATGLNEWKQVKAAHVS
KIRTLVNEANMLIDFVLADTGKGKITKAD
>SEQF1516_EDU84183.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIHLPHDAIRVTVFFDGCSNSTMSFSATELSGVWILSEGVSMSDLSLTQPKLKECPFCGGNARLWVEAGINIDVWGYAE
CDLCEARGAWAPSVAAAAEKWNRRAGDEANLSASQRSNQK
>SEQF1516_EDU84184.1 Kil protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDQTLMAIQTKFTIATFIGDEKMFREAVDAYKKWILMLKRRSSKSIH
>SEQF1516_EDU84185.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPIPVETDEEFHTLATSLSQKLEMMAAKAEANERDPA
>SEQF1516_EDU84186.1 repressor protein CI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHEIIGERIKSLREAKGLSQAQLAKLCGWAAPSRLGNYELGTRKVSADDALVLGAALGVSPAKIMFGEDSDAVFRQYEYP
LFSSVQAGPFSEVGSYTASDAKAWVPTTTKASEKAFWLEVKGHSMTAPQGVRPSFPEGMLILVDPAEPVESGDFCVASAN
GDSEATFKKYEKDAGVSYLVPLNPAYRTLDCDHSCRIIGKVVKAQWPEETFG
>SEQF1516_EDU84187.1 shiga toxin subunit B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKTLLIAASLSFFSASALATPDCVTGKVEYTKYNDDDTFTVKVGDKELFTNRWNLQSLLLSAQITGMTVTIKTNACHNG
GGFSEVIFR
>SEQF1516_EDU84188.1 Q protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTVFLWFIADGVKILMRDIRQVLECWGAWAANNHEDVTWSPIAAGFKGLIPEKVKSRPQCCDDDAMVICGCIARLYRNN
RDLHDLLVDYYVLGGTFMALARKHGCSDTCIGKRLHKAEGIVEGMLMMLGVRLEMDRYVERELPGGRTSVFYQRKNSLRS
>SEQF1516_EDU84189.1 phage recombination protein Bet [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQFIALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVD
GWSRIINENQQFDGMDFEQDNESCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCA
RLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDDDLLPLCSQIFRRDIRASSELTQ
AEAVKALGFLKQKATEQKVAA
>SEQF1516_EDU84190.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKACSVAASDKEKRIVTSVVMDDTEIIQTTSDDGGDDMDKRLAVLEAEVAHIKSSMAGIKEDTRKISSDSTDAKRDTAVL
LQKSLDFDASLSKKPSVDYFEAKFSALETKIADVKVWMLGVLLASLAMPTIFFLINLYLKKGQ
>SEQF1516_EDU84191.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGEREVNDSYRQFENWWSKDKSQFTGDDELKEFAWVIWQASRSAIELDIDWPESNDDLWKDGEEGAYAMGYEDGRDKTVI
AVMKAIRAAGIKEKNFD
>SEQF1516_EDU84192.1 ABC transporter, quaternary amine uptake (QAT) family, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEFSHVSKLFGAQKAVNDLNLNFQEGSFSVLIGTSGSGKSTTLKMINRLVEHDSGELRFAGEEIRSLPVLELRRRMGYA
IQSIGLFPHWSVAQNIATVPQLQKWSRARIDDRIDELMALLGLESNLRERYPHQLSGGQQQRVGVARALAADPQVLLMDE
PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDHGEVVQQGNPLTMLTRPANDFVRQFFGRSEL
GVRLLSLRSVADYVRREERAEGEALAEEMTLRDALSLFVARGCEVLPVVNTQGQPSGTLHFQDLLVEA
>SEQF1516_EDU84193.1 bacteriophage Lambda NinG protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKPARRKCKICKEWFHPAFSNQWWCCPEHGTQLALKLQSKQRKKAEKAAEKKRRREEQKQKDKLKIRKLALKPRSYWIK
QAQQAVNAFIRERDRDLPCISCGTLMSAQWDAGHYRTTAAAPQLRFDERNIHKQCVVCNQHKSGNLVPYRVELINRIGQE
AVDEIESNHNRHRWTIEECRAIKAKYQQKLKDLRNSRSEAA
>SEQF1516_EDU84194.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDGRSGRVRIGEFNNLFEHIDQQEYRKILAGTEQEMRLKKLRAMQRR
>SEQF1516_EDU84195.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEITSLVTAEAVKEVLRSEEVRSALKQKLRHNLEARLDAEVDAILDELLGAPAAPEPEGIAGEGSASDSGDPTPDSDMM
M
>SEQF1516_EDU84196.1 Ren protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTGKEAIIHYLGTHNSFCAPDVAALTGATVTSINQAAAKMARAGLLVIEGKVWRTVYYRFATREEREGKVSTNLIFKECR
QSAAMKRVLAVYGVKR
>SEQF1516_EDU84197.1 beta-glucosidase, periplasmic [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLALQPALADDLFGNHPLTPEARDAFVTELLKKMTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIR
AMQDQVMELSRLKIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVDVSRDPRWGRA
SEGFGEDTYLTSIMGKTMVEAMQGKSPADRYSVMTSVKHFAAYGAVEGGKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGA
VMVALNSLNGTPATSDSWLLKDVLRDQWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPG
LIKSGKVTMAELDDAARHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVARESLVLLKNRLETLPLKKS
ATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNAVGENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQE
MIDEAVQTAKQSDVVVAVVGEAQGMAHEASSRTDITILQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADAILET
WFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKPNKYTSRYFDEANGALYPFGYGLSYTT
FTVSDVKLSAPTMKRDGKVTASVQVTNTGKREGATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEAL
KFWNQQMKYDAEPGKFNVFIGTDSARVKKGEFELL
>SEQF1516_EDU84198.1 host-nuclease inhibitor protein Gam [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAYYIQDCLEAQSWARYYQQIAREEKEAELADDMEKGLPQHLFESLCIDHLQRHGASKKAITRAFDDDVEFQERMAEHI
RYMVETIAHHQVDIDSEV
>SEQF1516_EDU84199.1 SieB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNSWWQELMHFFLQGMTLKQLIHMLIILIILIIVMPVSVKEWINLHNPEILPHYWMYYILLFCVSYVLNGVVNSAYHAV
TERIEIFAAQKRKSKEEKYVQDLFDSLTLGERAYLAFAVAANNQLKTEKGSPEAISLLEKGLLIRVPSATGYPEIDRFVI
PERYRNECYIRFAGKKDSLMDELIAQDKHGKNK
>SEQF1516_EDU84200.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLIQPGFGLSIKKGHMFGEKESQRKMVSIRLPFISIYWLNREATNYWYTCARAAFNDPDWFVKNHHAVRQAKRKANMTY
MKAYQKAWKEHRDRYQQDMEKLESENMELRRKLGEAKRDIDAYKRLFNGESHA
>SEQF1516_EDU84201.1 ABC transporter, quaternary amine uptake transporter (QAT) family, substrate-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLSKVWAGSLVLLAAVSLPLHAASPVKVGSKIDTEGALLGNIILQVLESHGVPTVNKVQLGTTPVVRGAITSGELDIYP
EYTGNGAFFFKDENDAAWKNAQQGYEKVKKLDAEQNKLIWLTPAPANNTWTIAVRQDVAEKNKLTSLADLRRYLKEGGTF
KLAASAEFIERADALPAFEKAYDFKLDQDQLLSLAGGDTAVTIKAAAQQTSGVNAAMAYGTDGPVAAQGLQTLSDPQGVQ
PIYAPAPVVRESVLKEYPQMAQWLQPVFASLDAKTLQQLNASIAVEGLDAKKVAADYLKQKGWTK
>SEQF1516_EDU84202.1 shiga toxin subunit A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIIIFRVLTFFFVIFSVNVVAKEFTLDFSTAKTYVDSLNVIRSAIGTPLQTISSGGTSLLMIDSGTGDNLFAVDVRGID
PEEGRFNNLRLIVERNNLYVTGFVNRTNNVFYRFADFSHVTFPGTTAVTLSGDSSYTTLQRVAGISRTGMQINRHSLTTS
YLDLMSHSGTSLTQSVARAMLRFVTVTAEALRFRQIQRGFRTTLDDLSGRSYVMTAEDVDLTLNWGRLSSVLPDYHGQDS
VRVGRISFGSINAILGSVALILNCHHHASRVARMASDEFPSMCPADGRVRGITHNKILWDSSTLGAILMRRTISS
>SEQF1516_EDU84203.1 NinB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMCGAMQNVTSVKPGGHGHHQLLRRLKNGTGEQEMKQTFLLRNEAIRNNAIDAILSLPIDDKSPHEVHVKEPRRSKAQND
RMWPMLNDVSRQVLWHGQRLAPEDWKDLFTALWLKTKKLEQRSVPGIDGGVVMLGVRTSKMRKASMTELIEIMFWFGSER
NVRWSDDSRREYEWSQRKGRAA
>SEQF1516_EDU84204.1 peptidyl-prolyl cis-trans isomerase C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSGKRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHT
QFGYHIIKVLYRN
>SEQF1516_EDU84205.1 ketol-acid reductoisomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWR
KATENGFKVGTYEELIPQADLVVNLTPDKQHSDVVHTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTE
VREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDLMGEQTILCGMLQAGSLLCFDKL
VEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDRLSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADW
ANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLHELPLIANT
IARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDNAQLRDLNEAIRSHAIEQVGKKLRGY
MTDMKRIAVAG
>SEQF1516_EDU84206.1 ATPase, AAA family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLSIVHTRAALGVNAPPITVEVHISKGLPGLTMVGLPETTVKEARDRVRSAIINSGYEYPAKKITINLAPADLPKEGGR
YDLPIAIALLAASEQLTANKLDEYELVGELALTGALRGVPGAISSATEAIKSGRKIIVAKDNEDEVGLINGEGCLVADHL
QAVCAFLEGKHALERPKPTDAVSRALQHDLSDVVGQEQGKRGLEITAAGGHNLLLIGPPGTGKTMLASRINGLLPDLSNE
EALESAAILSLVNAESVQKQWRQRPFRSPHHSASLTAMVGGGAIPGPGEISLAHNGVLFLDELPEFERRTLDALREPIES
GQIHLSRTRAKITYPARFQLVAAMNPSPTGHYQGNHNRCTPEQTLRYLNRLSGPFLDRFDLSLEIPLPPPGILSKTVVPG
ESSTTVKQRVMAARERQFKRQNKLNAWLDSPEIRKFCKLESEDAQWLEETLIHLGLSIRAWQRLLKVARTIADIDQSDII
TRQHLQEAVSYRAIDRLLIHLQKLLT
>SEQF1516_EDU84207.1 hypothetical protein ECH7EC4501_5051 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKFIQLITHILIAVKTKNSINNQRDIINLPYISTAPEVGLKTLS
>SEQF1516_EDU84208.1 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLLTVSTDLISIFLFTTLFLFFARKVAKKVGLVDKPNFRKRHQGLIPLVGGISVYAGICFTFGIVDYYIPHASLYLACA
GVLVFIGALDDRFDISVKIRATIQAAVGIVMMVFGNLYLSSLGYIFGSWEMVLGPFGYFLTLFAVWAAINAFNMVDGIDG
LLGGLSCVSFAAIGMILWFDGQTSLAIWCFAMIAAILPYIMLNLGILGRRYKVFMGDAGSTLIGFTVIWILLETTQGKTH
PISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPDRQHIHHLIMRAGFTSRQAFVLITLAAALLASIGVLAEYSHFVPE
WVMLVLFLLAFLLYGYCIKRAWKVARFIKRVKRRLRRNRGGSPNLTK
>SEQF1516_EDU84209.1 transcriptional regulator IlvY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEEDLGQPLFVRDNRTVTLTEAGEELRVFAQQTLLQYQQLRH
TIDQQGPSLSGELHIFCSVTAAYSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSM
LENLAVVLIAPALPCPVRNQVSVEKPDWSTVPFIMADQGPVRRRIELWFRRNKISNPMIYATVGGHEAMVSMVALGCGVA
LLPEVVLENSPEPVRNRVMILDRSDEKTPFELGVCAQKKRLHEPLIEAFWRILPNHK
>SEQF1516_EDU84210.1 acetolactate synthase, isozyme II, small subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQNINIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTT
TSQQIRA
>SEQF1516_EDU84211.1 arylsulfatase-activating protein AslB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTHMDDDTLEAYVRHYIAASEPQNEVAFTWQGGEPTLLG
LEFYRRAVALQAKYGAGRKISNSFQTNGVLLDDEWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETTAREGLKLHAPGDIQGELTEWSVRPDEFGEF
LVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVCHHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMID
SPQQQVFGEDKFKQLPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLLAHGRPASD
IMQAHLLVVSK
>SEQF1516_EDU84212.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAINFSPKVGEILECNFGNYPVSQNGPFSTTYYDGRIPPEMIKNRLVVVLNGKINGNAFIVVPLSTTRDHDKLKRGMHVE
IASNVINDLQFFDQQIRWAKTDLVQQVSRNRLNRARTYRGYLNQCLPHELVADIQRAVIKSINAISLIN
>SEQF1516_EDU84213.1 TDP-D-fucosamine acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVRASIEPLTWENAFFGVNSAIVRITSEAPFLTPDALAPWSRVQAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNA
SDSGAVVAQETDIPALRQLASAAFAQSRFRAPWYAPDASSRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNA
TDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVESTAYWLYR
>SEQF1516_EDU84214.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRGRAAATATTRSLGENENSMQNAPVSCQQNDDVIKH
>SEQF1516_EDU84215.1 UDP-N-acetylglucosamine 2-epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLDQVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKP
ILAEFKPDVVLVHGDTTTTLATSLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLREN
VADSRIFITGNTVIDALLWVRDQVMSSDTLRSELAANYPFIDPDKKMILVTGHRRESFGRGFEEICHALADIATTHQDIQ
IVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPFVWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAG
TVRLVGTDKQRIVEEVTRLLKDENEYQTMSRAHNPYGDGQACSRILEALKNNRISL
>SEQF1516_EDU84216.1 guanosine-5'-triphosphate,3'-diphosphate diphosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAAGLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIR
VVATATLRLAVNAGDFIAKAQEILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSL
SMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQALQEIMMAQGMDERITLEKLQQLK
QRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIFTELNIQCMTLAGGALREGLVYGMLHLAVEQDIRSRTLRNIQRRF
MIDIDQAQRVAKVAANFFDQVENEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPAQKKLLATL
LLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMTLQANHELLTLTLPQGWLTQHPLGKEIIAQE
SQWQSYVHWPLEVH
>SEQF1516_EDU84217.1 branched-chain-amino-acid transaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYDSHKGPVVFRHREHMQRLHDSAKIYRFPVSQSIDELM
EACRDVIRKNNLTSAYIRPLIFVGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAK
AGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSALPGITRDAIIKLAKELGIEVREQ
VLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEGRCGPVTKRIQQAFFGLFTGETEDKWGWLDQVNQ
>SEQF1516_EDU84218.1 dTDP-glucose 4,6-dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKVDICDRAELARVFTEHQPDCVMH
LAAESHVDRSIDGPAAFIETNIVGTYTLLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPY
SASKASSDHLVRAWLRTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKPLPVYGNGQQIRDWLYVEDHARALYCVA
TTGKVGETYNIGGHNERKNLDVVETICELLEELAPNKPQGVVHYRDLITFVADRPGHDLRYAIDASKIARELGWLPQETF
ESGMRKTVQWYLANESWRKQVQDGSYQGERLGLKG
>SEQF1516_EDU84219.1 ATP-dependent DNA helicase Rep [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLM
ISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPAQAAAEAKGER
DRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVV
GDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGTELKVLSANNE
EHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDS
AFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRFTHWLAEIQRLAEREPIAAVRDLIH
GMDYESWLYETSPSPKAAEMRMKNVNQLFSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHAS
KGLEFPYVYMVGMEEGFLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRPEPSRFLLELPQDDLIW
EQERKVVSAEERMQKGQSHLANLKAMMAAKRGK
>SEQF1516_EDU84220.1 HemY protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGLAIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRK
RRRARKQTEQALLKLAEGDYQQVEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNDTIPVEITRV
RLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTGAWSSLLDIIPSMAKAHVGDEEHRAMLEQQAWIGLMDQAR
ADNGSEGLRNWWKNQSRKTRHQVALQVAMAEHLIECDDHDTAQQIIIDGLKRQYDDRLLLPIPRLKTNNPEQLEKVLRQQ
IKNVGDRPLLWSTLGQSLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTLQNNPPQ
>SEQF1516_EDU84221.1 TDP-Fuc4NAc:lipid II Fuc4Nac transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDDGLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRF
FFHGQFNPTLWLALLSGGIKPSQFYWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGEL
LYFPTRMDASLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVPMGYPPHNEAYIEEVRQAGLELF
SEENLQVLSEKLEFDAYLTLLRQCALGYFIFARQQGIGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDI
VREAQRQLASVDKNTIAFFSPNYLQGWQRALAIAAGEVA
>SEQF1516_EDU84222.1 transcriptional regulator HdfR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLGVNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARK
EVAHTSRHNEFSIGASASLWECMLNQWLGRLYQNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQIAMLNGCTWLPVSWARKKGGLH
TVVDSTTLSRPLYAIWLQNSDKNTLIRDLLKINVLDEVY
>SEQF1516_EDU84223.1 amino acid permease family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA
HRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP
AAMAKVSRHGVPVAGVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAAIASHPFRS
ILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGLNRHGKAHKLEE
>SEQF1516_EDU84224.1 ECA biosynthesis protein WzyE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFLLTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGC
FYAVYYVTYKTRLRKRVADVPRRPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKR
FFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIGIIRGWISLWMLAAAGVLGIVGM
FWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLALLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYF
TWEVLNNHSGLAISPTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIFNMIVLARE
GLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQVEG
>SEQF1516_EDU84225.1 dihydroxy-acid dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVD
DGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQII
KLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHSDRKQLFLNAGKRIV
ELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQK
YHMEDVHRAGGVIGILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFSQDCRWDTL
DDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVAGDVVVIRY
EGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQV
SDAELAARREAQEARGDKAWTPKNRERQISFALRAYASLATSADKGAVRDKSKLGG
>SEQF1516_EDU84226.1 glucose-1-phosphate thymidylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLAGIREILIITTPEDKGYFQRLLGDGSEFGIQLEYAEQ
PSPDGLAQAFIIGETFLNGEPSCLVLGDNIFFGQGFSPKLRHVAARTEVATVFGYQVMDPERFGVVEFDDNFRAISLEEK
PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRGFAWLDTGTHDSLIEASTFVQTV
EKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKTGYGQYLLELLRARPRQY
>SEQF1516_EDU84227.1 UDP-N-acetyl-D-mannosamine dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFATISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIVEPDLASVVKTAVEGGFLRASTTPVEADAWL
IAVPTPFKGDHEPDMTYVESAARSIAPVLKKGALVILESTSPVGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPER
VLPGQVMVELIKNDRVIGGMTPVCSARASELYKIFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICADQGINV
WELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVAQNPQQARLIRTAREVNDHKPFWVIDQVKAAVADCLAATDKRASE
LKIACFGLAFKPNIDDLRESPAMEIAELIAQWHSGETLVVEPNIHQLPKKLTGLCTLAQLDEALATADVLVMLVDHSQFK
VINGDNVHQQYVVDAKGVWR
>SEQF1516_EDU84228.1 arylsulfatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASAADTPSTATARKGFAGYDHPNQYLVKPATTIADNMMPVMQHPAQDKEPQQKLAELEKKTGKKPNVVVFLLDDVGWMD
VGFNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMYGQPGGLQGLTTLPQLLHDQG
YVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYTEWRDVHVNPEVALSPDRSEYIKQLPFSKDDVHAVRGGEQQAI
ADITPKYMEDLDQRWMEYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDVFANLYKAL
EKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWKGMIQPRKSDGIVDLADLFPTALDLAGHP
GAKVANLVPKTTFIDGVDQTSFFLGTNGQSNRKAEHYFLNGKLAAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTA
GSSVFNLYTDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD
>SEQF1516_EDU84229.1 threonine ammonia-lyase, biosynthetic [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRLDNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAH
GVITASAGNHAQGVAFSSARLGVKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHP
MVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSACLKAALDAGHPVDLPRVGLFAE
GVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKDLFEDVRAVAEPSGALALAGMKKYIAQHNIRGERLAHILSGANVN
FHGLRYVSERCELGEQREALLAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEERKEILQMLN
DGGYSVVDLSDDEMAKLHVRYMVGGRPSHPLQERLYSFEFPESPGALLRFLNTLGTHWNISLFHYRSHGTDYGRVLAAFE
LGDHEPDFETRLNELGYDCHDETNNPAFRFFLAG
>SEQF1516_EDU84230.1 acetolactate synthase, large subunit, isozyme II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNGAQWVVHALRAQGVNTVFGYPGGAIMPVYDALYDGGVEHLLCRHEQGAAMAAIGYARATGKTGVCIATSGPGATNLIT
GLADALLDSIPVVAITGQVSAPFIGTDAFQEVDVLGLSLACTKHSFLVQSLEELPRIMAEAFDVASSGRPGPVLVDIPKD
IQLASGDLEPWFTTVENEVTFPHAEVEQARQMLAKAQKPMLYVGGGVGMAQAVPALREFLATTKMPATCTLKGLGAVEAD
YPYYLGMLGMHGTKAANFAVQECDLLIAVGARFDDRVTGKLNTFAPHASVIHMDIDPAEMNKLRQAHVALQGDLNALLPA
LQQPLNINDWQQYCAQLRDEHAWRYDHPGDAIYAPLLLKQLSDRKPADCVVTTDVGQHQMWAAQHIAHTRPENFITSSGL
GTMGFGLPAAVGAQVARPNDTVVCISGDGSFMMNVQELGTVKRKQLPLKIVLLDNQRLGMVRQWQQLFFQERYSETTLTD
NPDFLKLASAFGIPGQHITRKDQVEAALDTMLNSDGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS
>SEQF1516_EDU84231.1 lipopolysaccharide biosynthesis protein WzzE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIALAYTFFARQEWSSTAITDRPTVNMLGGYYSQQQFLR
NLDVRSNMASADQPSVMDEAYKEFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIQFIPGDFTRAVNDS
VKLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKAIYDRRMNSIEQALKIAEQHNIS
RSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGPAFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSP
RRAFLMIMWGIVGGLIGAGVALTRRCSK
>SEQF1516_EDU84232.1 TDP-4-keto-6-deoxy-D-glucose transaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRFGSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSYT
FVSTANAFVLRGAKIVFVDVRPDTMNIDETLIEAAITDKTRVIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMST
YKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFRGQVDKYTWRDIGSSYLMSDLQA
AYLWAQLEAADRINQQRLALWQNYYDALAPLAKAGRIELPSIPDGCLQNAHMFYIKLRDIGDRSALINFLKEAEIMAVFH
YIPLHGCPAGERFGEFHGEDRYTTKESERLLRLPLFYNLSPVNQRTVIATLLNYFS
>SEQF1516_EDU84233.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGYAFNELDLGKREPVTEEEKLFVAVCRGEREPVTEAERVWSK
YMTRIKRPKRFHTLSGGKPQVEGAEDYTDSDD
>SEQF1516_EDU84234.1 glycosyl transferase, WecB/TagA/CpsF family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAINAEKMLTIEENAEVRELINAAEFKYADGISVVRSVR
KKYPQAQVSRVAGADLWEELMARAGKEGTTVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASG
AQIVTVAMGSPKQEIFMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWLYRLLSQPSRIKRQLRLLRYLRW
HYTGNL
>SEQF1516_EDU84235.1 transcription termination factor Rho [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAKSGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIY
VSPSQIRRFNLRTGDTISGKIRPPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTEMQRLVKGEVVASTFDEPASRHV
QVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNTVVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATAL
IDTGSKMDEVIYEEFKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGEIDAMEFLI
NKLAMTKTNDDFFEMMKRS
>SEQF1516_EDU84236.1 hypothetical protein ECH7EC4501_5074 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKTPRVYVAFCFYICNLNAALAMLGKFLEFAGMLCNLHIKWLIFAQDWWVRNGLSLLNKGLRGYTSANNFL
>SEQF1516_EDU84237.1 thioredoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILDEIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLL
LFKNGEVAATKVGALSKGQLKEFLDANLA
>SEQF1516_EDU84238.1 ATP-dependent RNA helicase RhlB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTLAGRDVAGQAQTGTGKTMAFLTSTFHCLLSHPAIADR
KVNQPRALIMAPTRELAVQIHADAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQ
VVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEYIEVEPEQKTGHRIKEELFYPSN
EEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHLAADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGL
HIPAVTHVFNYDLPDDCEDYVHRIGRTGRAGANGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTDLPKPLRLT
RPRTGNGPRRTGAPRNRRRSG
>SEQF1516_EDU84239.1 polysaccharide biosynthesis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLAKASLWTAASTLVKIGAGLLVGKLLAVSFGPAGLGLAANFRQLITVLGVLAGAGIFNGVTKYVAQYHDNPQQLRRVV
GTSSAMVLGFSTLMALVFVLAAAPISLGLFGNHDYQGLVRLVALVQMGIAWGNLLLALMKGFRDAAGNALSLIVGSLIGV
LAYYVSYRLGGYEGALLGLALIPALVVIPAAVMLIKRGAIPLSYLKPSWDNGLAGQLSKFTLMTLITSVTLPVAYIMMRK
LLAAQYSWDEVGIWQGVSSISDAYLQFITASFSVYLLPTLSRLTEKRDITREVVKSLKFVLPAVAAASFTVWLLRDFAIW
LLLSNKFTAMRDLFAWQLVGDVLKVGAYVFGYLVIAKASLRFYILAEVSQFTLLMVFAHWLIPTHGALGAAQAYMATYIV
YFSLCCGVFLLWRRRA
>SEQF1516_EDU84240.1 membrane protein, YeeE/YedE family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSMILSGLICGALLGFVMQRGRFCLTGGFRDMYIAKNNRMFYALLIAISVQSVGVFALIQAGLLTYEAGAFPWLGTVIG
GYLFGLGIVLAGGCATGTWYRAGEGLIGSWIALFTYMVMSAVMRSPHASGLNQTLQHYTTEHNSIAETFNLSVWPLVAVL
LVITLWVVMKELKKPKLKVATLPPRRTGIAHILFEKRWHPFVTAVLIGLIALLAWPLSEATGRMFGLGITSPTANILQFL
VAGDVKYINWGVFLVLGIFVGAFIAAKASREFRVRAADAQTTVRSGLGGVLMGFGASIAGGCSIGNGLVMTAMMTWQGWV
GLVFMILGVWTASWLVYVRPQRKARLATAAAN
>SEQF1516_EDU84241.1 IS66 family element, orf2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPS
ARDGKVFLTQAQLAMLLEGIDWRQPKRLLTSLTML
>SEQF1516_EDU84242.1 histidinol dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFNTIIDWNSCTAKQQRQLLMRPAISASESITRTVNDILDSVKARGDDALREYSAKFDKTTVTALKVSAEEIAAASERL
SDELKQAMAVAVKNIETFHTAQKLPPVDVETQPGVRCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCKKVVLC
SPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAKRQVSQRLDGAAIDMPAGPSEVL
VIADSGATPDFVASDLLSQAEHGPDSQVILLTPDADMAHQVAEAVERQLAELPRAETARQALNASRLIVTKDLAQCVEIS
NQYGPEHLIIQTRNARELVDGITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTVQELSKVGF
SALASTIETLAAAERLTAHKNAVTLRVNALKEQA
>SEQF1516_EDU84243.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMTLEADSVNVQALDMGHIVVDIDGVNITELINKAAENGYSLRVVDDRDSTETPATYASPHQLL
>SEQF1516_EDU84244.1 putative TonB-dependent receptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYNIPCRIYILSTLSLCISGIVSTATATSSETKISNEETLVVTTNRSASNLWESPATIQVIDQQTLQNSTNASIADNLQ
DIPGVEITDNSLAGRKQIRIRGEASSRVLILIDGQEVTYQRAGDNYGVGLLIDESALERVEVVKGPYSVLYGSQAIGGIV
NFITKKGGDKLASGVVKAVYNSATAGWEESIAVQGSIGGFDYRINGSYSDQGNRDTPDGRLPNTNYRNNSQGVWLGYNSG
NHRFGLSLDRYRLATQTYYEDPDGSYEAFSVKIPKLEREKVGVFYDTDVDGDYLKKIHFDAYEQTIQRQFANEVKTTQPV
PSPMIQALTVHNKTDTHDKQYTQAVTLQSHFSLPANNELVTGAQYKQDRVSQRSGGMTSSKSLTGFINKETRTRSYYESE
QSTVSLFAQNDWQFADHWTWTMGVRQYWLSSKLTRGDGVSYTAGIISDTSLARESASDHEMVTSTSLRYSGFDNLELRAA
FAQGYVFPTLSQLFMQTSAGGSVTYGNPDLKAEHSNNFELGARYNGNQWLIDSAVYYSEAKDYIASLICDGSIVCNGNTN
SSRSSYYYYDNIDRAKTWGLEISAEYNGWVFSPYISGNLIRRQYETSTLKTTNTGEPAINGRIGLKHTLVMGQANIISDV
FIRAASSAKDDSNGTETNVPGWATLNFAVNTEFGNEDQYRINLALNNLTDKRYRTAHETIPAAGFNAAIGFVWNF
>SEQF1516_EDU84245.1 ATP phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEE
LLNRRAQGEDPRYFTLRRLDFGGCRLSLATPVDDAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPR
AGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQGVIQARESKYIMMHAPTQRLDE
VIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME
>SEQF1516_EDU84246.1 serine-type D-Ala-D-Ala carboxypeptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLKRRLIIAASLFIFNLSSGFAAENIPFSPQPPEIHAGSWVLMDYTTGQILTAGNEHQQRNPASLTKLMTGYVVDRAID
SHRITPDDIVTVGRDAWAKDNPVFVGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYAEK
LHLKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRNGLLWDKTMNVDGLKTGHTSG
AGFNLIASAVDGQRRLIAVVMGADSAKGREEEARKLLRWGQQNFTTVQILHRGKKVGTERIWYGDKENIALGTEQEFWMV
LPKAEIPHIKAKYTLDGKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEGSMFSRLSDYFHHKA
>SEQF1516_EDU84247.1 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTLANLLNTIPAIDPAAMSRAQRHIDGLLKPVGSLGRLEALGVQLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAIS
PKEVTAIQAENMTRGTTGVCVLAAQAGANVHVIDVGIDTAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYT
RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVVRRAITLNQPNPQDGVNVLAKVG
GFDLVGMAGVMLGAASCGLPVLLDGFLSYAAALAACQMSPAIKPYLIPSHLSAEKGARIALSHLGLEPFLNMDMRLGEGS
GAALAMPIIEAACAIYNNMGELAASKIVLPGNTTSDLNS
>SEQF1516_EDU84248.1 exodeoxyribonuclease I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMNDGKQQSTFLFHDYETFGTHPALDRPAQFAAIRTDDEFNVIGEPEVFYCKPADDYLPQPGAVLITGITPQEARAKGEN
EAAFAARIHSLFTVPKTCILGYNNVRFDDEVTRNVFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPENDDG
LPSFRLEHLTKANGIEHSNAHDAMADVYATIAMAKLVKTRQPRLFDYLFTHRNKHKLMALIDVPQMKPLVHVSGMFGAWR
GNTSWVAPLAWHPENRNAVIMVDLAGDISPLLELDSDTLRERLYTAKTDLGDNAAVPVKLVHINKCPVLAQANTLRPEDA
DRLGINRQHCLDNLKILRENPQVREKVVAIFAEAEPFTPSDNVDAQLYNGFFSDADRAAMKIVLETEPRNLPALDITFVD
KRIEKLLFNYRARNFPGTLDYAEQQRWLEHRRQVFTPEFLQGYAEEIQMLAQQYADDKEKVALLKALWQYAEEIV
>SEQF1516_EDU84249.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHYLADRAGIRGLFSDADAYHPDQAFPLLMKQLELMLTSGELNPRHQHTVTLYAKGLTCKADTLSSCGYVYLAVYPTPEM
KN
>SEQF1516_EDU84250.1 phospholipase, patatin family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTEMKTGLVLSGGGAVGAYQAGVVKALAECGTQISMVSGASIGAFNGAIIAASTDLSEAAVRLEALWDHLGNNQVLSVN
RLVYFSLLKKLFQAMNLCQIPGRAGALLTTLLRHISTINGFDNLMAQPLLSDEPLTALMDHYLDTDALADGLPLYVSLYP
TEGGMQDIIDCIRAELGVGTTKNAVFQHIQSLPRGQQKEALLASAALPLLFRPREVQGTMFGDGGMGGWRNMQGNTPVTP
LVDAGCNMVIVTHLSDGSLWDRQAFPDTTILEIRPRKRLKYAGDGGNSGGLLSFTSAHTDAWCQQGYEDTMLAMEHIRKP
LAARQALTRSEAVLQKSLDITEEADLALRNAMARIK
>SEQF1516_EDU84251.1 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAEVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGG
GVRSEEDVAALLEAGVARVVVGSTAVKSPEMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETY
LPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDINDVAALRGTGVRGVIVGRALLEGKFTVKEAIS
CWQNA
>SEQF1516_EDU84252.1 UDP-glucose 6-dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKITISGTGYVGLSNGLLIAQNHEVVALDILPSRVAMLNDRISPIVDKEIQQFLQSDKIHFNATLDKNEAYRDADYVIIA
TPTDYDPKTNYFNTSSVESVIKDVVEINPYAVMVIKSTVPVGFTEAMHKKYRTENIIFSPEFLREGKALYDNLHPSRIVI
GERSERAERFAALLQEGAIKQNIPTLFTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLNSRQIIEGVCLDPRIGN
HYNNPSFGYGGYCLPKDTKQLLANYQSVPNNLISAIVDANRTRKDFIADAILSRKPQVVGIYRLIMKSGSDNFRASSIQG
IMKRIKAKGVEVIIYEPVMKEDSFFNSRLERDLATFKQQADVIISNRMAEELRDVADKVYTRDLFGSD
>SEQF1516_EDU84253.1 imidazoleglycerol phosphate synthase, cyclase subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGADELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVA
GGIKSLEDAAKILSFGADKISINSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETL
DWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLEAFRDADVDGALAASVFHKQIIN
IGELKAYLATQGVEIRIC
>SEQF1516_EDU84254.1 hypothetical protein ECH7EC4501_0031 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKVYCLRGLSLASHALSGFPVTMAGAVFTFDINNVQRNAWFTP
>SEQF1516_EDU84255.1 cobinamide kinase/cobinamide phosphate guanyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARIEHHRQGRPEHWRTVERWQHLDELIHADINPNEVVLL
ECVTTMVTNLLFDYGGDKDPDEWDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
QLAAAANEVWLVVSGIGVKIK
>SEQF1516_EDU84256.1 antirestriction protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTVSQNTPTIYSATTPENNPPQLVASLVPDEQRISFWPQHFGLIPQWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGG
AFMAPEPDDDDDETWVLFNAMNGNRAEMSPEAAGIAACLMTYSHHACRTENYAMTVHYYRLRDYALQHPEGSAIMRIID
>SEQF1516_EDU84257.1 IS629 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSAHAQHDDWLKKEIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVSAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGCI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTQRLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRTEVELATLTWVDRYNNRRLLERLGHIPPAEAEKAYYASIGNNDLAA
>SEQF1516_EDU84258.1 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDKTIESGKVTFFSRTKQRLWTKGETSGNFLNVVNIAPD
CDNDTLLVLANPIGPTCHKGTSSCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
ATVHDRFELTNEASDLMYHLLVLLQDQDLDLTTVIENLRKRHQ
>SEQF1516_EDU84259.1 chain length determinant protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVENNNVSGQNHDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAIGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVI
YGQAAPKVSDLQETLIGRFSSAFSALAETLDNQEEPEKLTIEPSVKNQQLPLTVSYVGQTAEGAQMKLAQYIQQVDDKVN
QELEKDLKDNIALGRKNLQDSLRTQEVVAQEQKELRIRQIQEALQYANQAQVAKPQVQQTEDVTQDTLFLLGSEALESMI
KHEATRPLVFSPNYYQTRQNLLDIENLKVDDLDIHAYRYVMKPTLPIRRDSPKKAITLILAVLLGGMVGAGIVLGRNALR
NYNAK
>SEQF1516_EDU84260.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKCWLREAGAHNVLVTSAVNNNGVTELFALLHTEEGCR
>SEQF1516_EDU84261.1 DNA repair protein, RadC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQQISFLPGEMTPGERSLIQRALKTLDRHLHEPGVAFTSTRAAREWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGT
INRTEVHPREVIKRALYHNAAAVVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGNQVFSFAEHGLL
>SEQF1516_EDU84262.1 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVVILGTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFLPGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGM
QLLGRRSEESNGVDLLGIIDEDVPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYG
EPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM
>SEQF1516_EDU84263.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYI
IKNAELSKERRDISKKLKAMGEMKNGEAK
>SEQF1516_EDU84264.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAVRMVLESQGEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGSGDGGLTTAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU84265.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPLLDVLMILDALEKEGSFAAASAKLYKTPSALSYTVHKLESDLNIQLLDRSGHRAKFTRTGKMLLEKGREVLHTVREL
EKQAIKLHEGWENELVIGVDDTFPFSLLAPLIEAFYQHHNVTRLKFINGVLGGSWDALTQGRADIIVGAMHEPPSSSEFG
FSRLGDLEQVFAVAPHHPLAQEEEPLNRRIIKRYRAIVVGDTAQAGASTASQLLDEQEAITVFDFKTKLELQISGLGCGY
LPRYLAQRFLDSGALIEKKVVAQTLFEPVWIGWNEQTAGLASGWWRDEILANSAIAGVYAKSDDGKSAI
>SEQF1516_EDU84266.1 histidinol-phosphate aminotransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVEFQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLV
SRGADEGIELLIRAFCEPGKDAILYCPPTYGMYSVSAETIGVECRTVPTLENWQLDLQGISDKLDGVKVVYVCSPNNPTG
QLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFALAGLRCGFTLANEEVINLLMKVI
APYPLSTPVADIAAQALSPQGIIAMRERVAQIIAEREYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGII
LRDQNKQPSLSGCLRITVGTREESQRVIDALRAEQV
>SEQF1516_EDU84267.1 hypothetical protein ECH7EC4501_0046 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKEAAIIRRRFNSKPSGVSNSCSFYGNTYELAGIKCKKM
>SEQF1516_EDU84268.1 hypothetical protein ECH7EC4501_0065 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYSVNKALVKYCRTDAGYNFGYNIVNRDNKNLLSQLF
>SEQF1516_EDU84269.1 hypothetical protein ECH7EC4501_0022 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEWKGYKFDKVYYITFHPSLIQSTNDCCNDNYFHLCSHISIIIVIFINCKYQTFLTLIMFFDRYFTTEHIRRFL
>SEQF1516_EDU84270.1 DNA gyrase inhibitory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNYEIKQEDKRTVAGFHLVGPWEQTVKKGFEQLMMWVDSKNIVPKEWVAVYYDNPDETPAEKLRCDTVVTVPNNFTLPEN
SEGVILTEISGGQYAVAVARVVGDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH
>SEQF1516_EDU84271.1 IS66 family element, transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQLDKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTL
TGRVYDPAVQRPLRQTRTRKPFPESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
DAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELRRSLLSGWVDACCRLLSPLEEALHGYVMT
DGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNAGSALAPAVWFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELY
RNGGITEAACWAHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWLREKMKT
LSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKNFLFFGSDHGGERGALLYSLIGTCKLNDVDP
ESYLRHVLGVIADWPVNRVSELLPWRIALPAE
>SEQF1516_EDU84272.1 hypothetical protein ECH7EC4501_0024 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKTIVMEFFVLICPLCGQANERIVFVEGFSTLFSICG
>SEQF1516_EDU84273.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRANKSLSPFEIRVYRHYRIVHGTRVALAFLLTFLIIRLFTIPEGTWPLVTMVVIMGPISFWGNVVPRAFERIGGTVLGS
ILGLIALQLELISLPLMLVWCAAAMFLCGWLALGKKPYQGLLIGVTLAIVVGSPTGEIDTALWRSGDVILGSLLAMLFTG
IWPQRAFIHWRIQLAKSLTEYNRVYQSAFSPNLLERPRLESHLQKLLTDAVKMRGLIAPASKETRIPKSIYEGIQTINRN
LVCMLELQINAYWATRPSHFVLLNAQKLRDTQHMMQQILLSLVHALYEGNPQPVFANTEKLNDAVEELRQLLNNHHDLKV
VETPIYGYVWLNMETAHQLELLSSLICRALRK
>SEQF1516_EDU84274.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIKKLDVVTQVCPFPLIEAKAALAEMASGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQIGDAAWSITVQKA
>SEQF1516_EDU84275.1 histidinol-phosphatase/imidazoleglycerol-phosphate dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPQLLKLQKAGYKLVMITNQDGLGTQSFPQADFDGPHNLMMQIF
TSQGVQFDEVLICPHLPADECDCRKPKVKLVERYLAEQAMDRANSYVIGDRATDIQLAENMGINGLRYDRETLNWPMIGE
QLTRRDRYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEINVKGDLYIDDHHTVEDTGLALG
EALKIALGDKRGICRFGFVLPMDECLARCALDISGRPHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGK
NDHHRVESLFKAFGRTLRQAIRVEGDTLPSSKGVL
>SEQF1516_EDU84276.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLASRFGYAANQIRRDRPLTHEELIRHVPSIFGEDRHTSRSERYAYIPTITVLENLQREGFQPFFACQTRVRDPGRRGY
TKHMLRLRRAGEINGEHVPEIILLNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVEKVIEGAYEVVGVF
DRIEEKRDAMQSLVLPQPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWSAYQTIQENMLKGGISGRSAKG
KRIHTRAIHSIDTDIKLNRALWVMAETMLESLR
>SEQF1516_EDU84277.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIITRGEAMRIHQQHPTSRLFPFCTGKYRWHGSAEAYTGREVQDIPGVLAVFAERRKDSFGPYVRLMSVTLN
>SEQF1516_EDU84278.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQIESTVTSLHREAEAQFRPELEKIVSGIETGFRGTALYATENIAGRINARLEDEGFTVKISFPAVSQLQTRLAVKINL
SALMEERTETVTRRRRQSGVWGTVCRWFGTSDLGWENYDEDVSRSVININKVREEVMSLTRAYFGELQASIEQDINQPVR
QEIDAFFCAFREKVEQLRNTLIQSSEDHKRDQQAQERLTGRLQALNERVPELITDSKALREELETML
>SEQF1516_EDU84279.1 NAD dependent epimerase/dehydratase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKVAIVGLGWLGMPLAMSLSARGWQVTGSKTTQDGVEAARMSGIDSYLLRMEPELVCDSDDLDALMDADALVITLPARR
SGPGDEFYLQAVQELVDSALAHRIPRIIFTSSTSVYGDAQGTVKETTPRNPVTNSGRVLEELEDWLHNLPGTSVDILRLA
GLVGPGRHPGRFFAGKTAPDGEHGVNLVHLEDVIGAITLLLQAPKGGHIYNICAPAHPARNVFYPQMARLLGLEPPQFRN
SLDSGKGKIIDGSRICNELGFEYQYPDPLVMPLE
>SEQF1516_EDU84280.1 hypothetical protein ECH7EC4501_0030 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLPVKLLMSLISLVRVIARAGEYKNYSRDEIKYWRYTSYKGGKLPEGFTDEKFSSAIYNGRIFTMKRLHTLMLFLAVLF
TGFNFNAEAATVKQALSCNPEAWAEQPGACPSTYELYEGDATYKAAIDKALKPVGLSGMFGKGGYMDGPGGGITPVNING
TVWFQGDGCKANTCGWDFIVTLYNPKTHEVVGYRYFGLDDPAYLVWFGEIGVHEFAYLVKNYVAAVN
>SEQF1516_EDU84281.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSPFIQQIADNRVCQVLTCLPEKFVVDFANGIDVAQEHIRTAGERTFFRRLKEGLTGEGAARQNAINASLAQGVEASLR
WLTEMTTSLATTNYAITRVNDRVSSLVSDTARLAHYSADTREQLLTLADQVHHKLNHLEEKLHRVDQVQRAQLHLEQIFS
WWSAGRYASFSPAGRCYVALEELRWGAFGDVIRQSETGQVNQLLDILRHKALTQMAQESGGSATVRLNTLDWLGGQGREQ
ADNEWHDAINWLGDWCSEEQHPVIWSTTQAAEHLPVRMPRLCSAERLSESMVDEIFQKGAA
>SEQF1516_EDU84282.1 amino acid permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVSGLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAG
SAYTYAQKSISPTVGFMVGWSSLLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIV
VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFDGISNLSEETKDAERVIPRAIFL
TALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEIMLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGV
FPKSFFGYVHPKWRTPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLKDHFQYLFL
PMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYEDVA
>SEQF1516_EDU84283.1 cobalamin 5'-phosphate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLLGAISGLVFMVLQAWCGAPLAALFSVLVLVLMTGGFH
LDGLADTCDGVFSARSRDRMLEIMRDSRLGTHGGLALIFVVLAKILVLSELALRGEPILASLAAACAVSRGTAALLMYRH
RYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQLLKRTLGGQTGDTLGAAIELGEL
VFLLALL
>SEQF1516_EDU84284.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLITHLLNVEELSRLLKNVALSVINLFILDDVSEKMEYIPDWVVVTRLNIWWC
>SEQF1516_EDU84285.1 hypothetical protein ECH7EC4501_0032 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTFIKTLLVAVTILFSVFATAKQVKLPNNIKYVNTTEAFSCTEIDGMNCQTKNQFNYKDNSYVFVLERGGAWCYDYTVS
VVNLKTGKAQMIEYGDNQLCSGSNKPFFEIKNGVPTVGVIDTSGKPVGVAQDKLKI
>SEQF1516_EDU84286.1 6-phosphogluconate dehydrogenase, decarboxylating [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPGKKLVPYYTVKEFVESLETPRRILLMVKAGAGT
DAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIA
AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQIFTEWNNGELSSYLIDITKDIFT
KKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEK
VRRALYLGKIVSYAQGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAENPQIANLLLAPYFKQIADDY
QQALRDVVAYAVQNGIPVPTFAAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRIDKEGVFHTEWLD
>SEQF1516_EDU84287.1 IS66 family element, orf1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLDAAAEQPESLAEDPETLSISCEVTFRHGTLRFNGNVSEKLLTLLIQELKR
>SEQF1516_EDU84288.1 L-arabinose isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVKALNTEAKLPCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWL
HTFSPAKMWINGLTMLNKPLLQFHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVVNSISDGDVNALVDEYESCYTMT
PATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFTTTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKV
MSTGLQGGTSFMEDYTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAIVASLIDLG
DRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHHTVFSHALNLNDMRQFAEMHDIEITVIDNDT
RLPAFKDALRWNEVYYGFRR
>SEQF1516_EDU84289.1 cell division protein FtsL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFICIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIE
WRNLILEENALGDHSRVERIATEKLQMQHVDPSQENIVVQK
>SEQF1516_EDU84290.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKKTENMNIFEELWETLRNLFQSDKHSQTAARQILKDAFYFQNSDDYSKYFTGAVDGKARDKLTHWLIKFNELKEYAKD
PENMAAKASLSPEGTLCVSFFIGDEAIFTLELQLKKSTRTGGIDLSNAYFNGVVICGIDCLEVDLSNAETNNSRWYD
>SEQF1516_EDU84291.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHP
SLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELS
SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALTMPIRGADERCVSFGVNMGDYHL
NHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSK
ATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGVQLAALRPEVAEQTETMEQAMRLLAP
RVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG
>SEQF1516_EDU84292.1 L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPSGVDYSIMTADDMVVVSIETGEVVEGAKKPSSDTPTH
RLLYQAFPSIGGIVHTHSRHATIWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKHYLRKHGAKAYYGQ
>SEQF1516_EDU84293.1 arabinose operon regulatory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQYGQLVSSLNGGSMKSMAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKGYILNLTIRGQGVVKNQGRE
FVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQG
EGRYSELLAINLLEQLLLRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQLGISV
LSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEFRAGCEEKVNDVAVKLS
>SEQF1516_EDU84294.1 sugar transport-related sRNA regulator SgrR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLLNTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQR
AEDLLEQDRIDQLVQLVGDKATVRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIADIVSPTPWTLDIHLTQPDRWLP
LLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRNSTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGP
QGEEKEIESRLEEGCYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHARTITSEKPAG
LESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIESDIWLNSANFTLPLDFSLFAHLCEVPLLQHC
IPIDWQVDAARWRNGEMNLANWCQQLVASKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDPE
>SEQF1516_EDU84295.1 3-isopropylmalate dehydratase, large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGLRAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMAR
IQMQELIKNCKEFGVELYDLNHPYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMTLCNMAIEMGAKAGLVAPDETTF
NYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTVVTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAE
KALAYMGLKPGILLTEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLDKIFIEAGF
EWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMAAAAAVTGHFADIRNIK
>SEQF1516_EDU84296.1 L-ribulokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIAIGLDFGSDSVRALAVDCTTGEEIATSVEWYPRWQKGQFCDAPNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAV
VGIGVDSTGSTPAPIDADGNVLALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKI
LHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLPPASFFDELDPILNRHLPSPLFT
DTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCHMGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQV
DGSVVPGFIGLEAGQSAFGDIYAWFGRVLGWPLEQLAAQHPELKEQIDASQKQLLPALTEAWAKNPSLDHLPVVLDWFNG
RRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGIAVNNVMALGGIARKNQVIMQACCDVLNRPL
QIVASDQCCALGAAIFAAVAAKVHADIPSAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAA
QAVPTL
>SEQF1516_EDU84297.1 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGHQADGRRYIPQAIAQGVAAIIAEAKGEATDGEIREMH
GVPVIYLSQLNERLSALAGRFYHEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
SAVDVQHELAGLVDQDATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDMEHYEAAKWLLYSEHHCGQAIIN
ADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKATEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLL
ALGYPLADLLKTAARLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDKGKRPLMGA
IAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEDRAEAVTCAVMQAKENDVVLVAGKGHEDYQIVGNQRLD
YSDRVTVARLLGVIA
>SEQF1516_EDU84298.1 peptidoglycan synthetase FtsI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAWLQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGR
PLAVSVPVKAIWADPKEVHDAGGISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVIEDISSTDSQAAHNLALSIDERL
QALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMANSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQR
GVVRENSVLNTIPYRINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLGLVGERSGL
YPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVDPPVPGERVFPESIVRTVVHMMESVALPGGG
GVKAAIKGYRIAIKTGTAKKVGPDGRYINKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRT
MNIEPDALTTGDKNEFVINQGEGTGGRS
>SEQF1516_EDU84299.1 fructose repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVREHNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIA
NYLERQARQRGYQLLIACSEDQPDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYANSYEREAAAQLFEKWLETHPMPQ
ALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDNELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTR
IKRNLYRRGVLSRS
>SEQF1516_EDU84300.1 DNA polymerase II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAFIPADQVPRAQHILRGEQGFRLTPLALKDFHRQPVYG
LYCRAHRQLMNYEKRLREGGVTVYEADVRPPERYLMERFITSPVWVEGDMHNGAIVNARLKPHPDYRPPLKWVSIDIETT
RHGELYCIGLEGCGQRIVYMLGPENGDASALDFELEYVASRPQLLEKLNAWFANYDPDVIIGWNVVQFDLRMLQKHAERY
RIPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIIDGIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRR
FAEDKPALATYNLKDCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLGEVPPHASP
GGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHSTEGFLDAWFSREKHCLPEIVTNIWHGRDEA
KRQGNKPLSQALKIIMNAFYGVLGTTACRFFDPRLVSSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEE
EATKIGRALVQHVNVWWAETLQKQQLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEGDKQRMVFKGLETVRTD
WTPLAQQFQQELYLRIFRNEPYQEYFRETIDKLMAGELDARLVYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPL
QYQNRGTIKYVWTTNGPEPLDYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF
>SEQF1516_EDU84301.1 transcriptional regulator LeuO [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPEVQTDHPETAEFSKPQLRMVDLNLLTVFDAVMQEQNITRAAHVLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTA
RAFQLFGSVRQALQLVQNELPGSGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDRFASFSQPWYDTVDKQASIAYQG
MAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVLPLPLKLNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR
>SEQF1516_EDU84302.1 acetolactate synthase, small subunit, isozyme III [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLSRMTIQTVGDEKVLEQIEKQLYKLVDVLRVSELGQGA
HVEREIMLVKIQASGYGRDEVKRNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
IMR
>SEQF1516_EDU84303.1 2-isopropylmalate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKD
IDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAVHAGARQVEGAMNGIGERAGNCS
LEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQICNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIG
LNQIQLNLTSRSGRAAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFRLDYFSVQS
GSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYSLTAKGHGKDALGQVDIVANYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRATEVEKELQRKAQHNENNKETV
>SEQF1516_EDU84304.1 thiamine/thiamine pyrophosphate ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWSAVWQDSYLWHVVRFSFWQAFLSALLSVVPAIFLARA
LYRRRFPGRLALLRLCAMTLILPVLVAVFGILSVYGRQGWLASLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
ALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVTALIFMLCFASFATVLSLGGGPQATTIELAIYQALSYDYDP
ARAAMLALIQMVCCLGLVLLSQRLSKAIAPGTTLLQGWRDPDDRLHSRICDTMLIVLALLLLLPPLLAVIVDGVNRQLPE
VLAQPVLWQALWTSLRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFLLLNNTIGL
PQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRLKVVELRALKRPLAQALAFACVLSIGDFGVV
ALFGNDDFRTLPFYLYQQIGSYRSQDGAVTALILLLLCFLLFSVIEKIPGRNVKTD
>SEQF1516_EDU84305.1 pseudouridine synthase, RluA family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKDSVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAE
RELKRQFRERVPKKQYVTRVWGHPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPADF
>SEQF1516_EDU84306.1 cell division protein FtsQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWVVLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILA
LGEPGTFMTQDVNIIQTQIEQRLPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPDRTSKQVLPML
YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMKRLARFVELYPVLQQQAQTDGKR
ISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
>SEQF1516_EDU84307.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIV
KDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
ANHQGEIVWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPI
QLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTA
SGVGEHFAEKTALITRLKSLIAEQQVITILVKGSRSAAMEEVVRALQENGTC
>SEQF1516_EDU84308.1 UDP-N-acetylmuramate--alanine ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGYQISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDAS
VVVVSSAISADNPEIVAAHEARIPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFLHNLPFYGRAVMCVDDPVIRELL
PRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLRQDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALES
FQGTGRRFDFLGEFPLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYDDFANVLTQ
VDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEMLAPVLTGNDLILVQGAGNIGKIARSLAEIKL
KPQTPEEEQHD
>SEQF1516_EDU84309.1 cell division protein FtsA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSRGMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVY
LALSGKHISCQNEIGMVPISEEEVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDIAVYTGGALRHTKVIPYAGNVVT
SDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVEVPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLR
QQGVKHHLAAGIVLTGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLNGEAEVEKR
VTASVGSWIKRLNSWLRKEF
>SEQF1516_EDU84310.1 3-isopropylmalate dehydratase, small subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLFNDWRFLDEKGQQPNPDFVLNFSQYQGASILLARENF
GCGSSREHAPWALTDYGFKVVIAPSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
RFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMR
>SEQF1516_EDU84311.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDYYAVVNDAFHGNGFCFYKNPYLYVFLILLIFLFLILYA
>SEQF1516_EDU84312.1 thiamin/thiamin pyrophosphate ABC transporter, periplasmic thiamin/thiamin pyrophospate-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAFEADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVL
GLDNNLLDAASKTGLFAKSGVAADAVNVPGGWNNDIFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRT
STPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTSPAYHILEEKKDNYAAANFSEGH
YLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIPTGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISE
WQRAVSR
>SEQF1516_EDU84313.1 acetolactate synthase, large subunit, isozyme III [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGIGHVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGAT
NAITGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
LPKDILNPANKLPYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAITAGCHQQLKETVEALNLPVVSS
LMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVIFAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPI
VGDARQVLEQMLELLSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGGAYVTSDVGQHQM
FAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYELPVLVVNLNNRYLGM
VKQWQDMIYSGRHSQSYMQSLPDFVRLAEAYGHVGIQISHPQELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRG
GGMDEMWLSKTERT
>SEQF1516_EDU84314.1 S-adenosyl-methyltransferase MraW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQLGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFS
ALGEYVAERDLIGKIDGILLDLGVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIIS
FHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKLGGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA
>SEQF1516_EDU84315.1 MraZ protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPCLLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGH
ASECQMDGAGRLLIAPVLRQHAGLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL
>SEQF1516_EDU84316.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAGLGALIGSGELSFWHAWLAGIVGCLLGDWISFWLGWR
FKKPLHRWSFLKKNKALLDKTEHALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGI
LAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLLWLTPLISAIGVVALVVLVRHPL
MPVYIDILRKVVGV
>SEQF1516_EDU84317.1 phospho-N-acetylmuramoyl-pentapeptide-transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRMIAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMIL
TAIVISVLLWAYPSNPYVWCVLVVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPATQL
VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWATGNMNFASYLHIPYLRHAGELV
IVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGALGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFR
MAPIHHHYELKGWPEPRVIVRFWIISLMLVLIGLATLKVR
>SEQF1516_EDU84318.1 D-alanine--D-alanine ligase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKEVDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMG
LPYTGSGVMASALSMDKLRSKLLWQGAGLPVAPWVALTRVEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAE
NALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSVRIQPSGTFYDYEAKYLSDETQYFCPAGLEASQEANLQAL
VLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPGMTSHSLVPMAARQAGMSFSQLVVRILELAD
>SEQF1516_EDU84319.1 3-isopropylmalate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPK
WEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPDIELAHMYIDNATMQLIKDPSQF
DVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAAS
AIERAINRALEEGIRTGDLARGAAAVSTDEMGDIIARYVAEGV
>SEQF1516_EDU84320.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADRMEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRI
FNAWRQARAIMKAYKPDVVLGMGGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQSGKGSQQSVEQAYAEAGQPQHKV
TEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPALFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAG
WSRETLLTMAERARAASIPDATERVANEVSRAARA
>SEQF1516_EDU84321.1 thiamine ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNLIAGFLTPASGALTIDGVDHTTTPPSRRPVSMLFQEN
NLFSHLTVAQNIGLGLNPGLKLNAVQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
DPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGMTNELLSGKASASALLGITG
>SEQF1516_EDU84322.1 RNA polymerase associated protein RapA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYARSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGL
LTYIGTRLDTEESGVALREVFLDSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVEMLRRFNLRFALFDDERYAEAQH
DAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDLLVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLG
MESHFARLRLLDPNRFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSDSEDAQSAR
QELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKVSGIMGARKSAEDRARDMLYPERIYQEFEGD
NATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVL
LCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRWYHEGLDAFEHTCPTGR
TIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLEQGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAM
NLFDIIGINQDDRGDNMIVLTPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGSST
ISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQVEFETFNRQLNAVNRHTGSKLVNAV
QQDVHAILQLGEAQIEKSARALIDAARNEADEKLSAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDAL
RLIVVTHQ
>SEQF1516_EDU84323.1 hypothetical protein ECH7EC4501_6074 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIINRLNPTTYSNFSIFLINPKIESPHIQNKILHSIKNAE
>SEQF1516_EDU84324.1 cell division protein FtsW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMYDRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFF
FAKRDGVYLILAFILAIITLRLPMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGISAVVLLILAE
PYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGELWGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVF
FVAFRAMSIGRKALEIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIMMLLRIDYE
TRLEKAQAFVRGSR
>SEQF1516_EDU84325.1 oxoglutarate dehydrogenase (succinyl-transferring), E1 component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTI
SDPDTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEAL
KQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDALIPMLK
EMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNP
SHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPL
DARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQKIKKH
PTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKR
ISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYT
PLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPH
GYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFL
PAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQG
AWYCSQHHFREVIPFGASLRYAGRPASASPAVGYMSVHQKQQQDLVNDALNVE
>SEQF1516_EDU84326.1 succinate-CoA ligase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKR
LVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQG
RELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDP
REAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFG
GIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK
>SEQF1516_EDU84327.1 putative fimbriae structural protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKGQKTLAALAISLLFASPVFAADEGSGEIHFKGEVIEAPCEIHPDDLDMNIDLGEVTTSHINREHHSEKKPVNIRLIN
CDIAGWDDGKGGVVSKVGVTFDSTAKTTGATPLLSNISAGEATGVGVRLMNKDESFVTLGTEAPTIDLLASSTEQTLNFF
AWMEQMDNAVSVTAGAVTANATYVLDYQ
>SEQF1516_EDU84328.1 methylaspartate mutase, E subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELRNKKLTHDEFMTERQQVLKTWETGKDVENFEDGVKYQQTIPEHKRFSLALLKADKEGKTLSQPRAGVALMDEHIELL
KTLQEECDLLPSTIDAYTRLNRYEEAAVGIKKSIEAGTSKLNGLPVVNHGVAACRRLTETLQKPLQIRHGTPDARLLAEI
SMASGFTSYEGGGISYNIPYAKRVTLEKSIRDWQYCDRLMGMYEEHGIRINREPFGPLTGTLIPPFISHSIAIIEGLLAL
EQGVKSITVGYGQVGSLTQDVAAIQSLRELAHEYFQSYGYTDYELSTVFHQWMGGFPEDESKAFAIISWGAAVAGMSGAT
KVITKSPHEAWGIPTAAANIQGLKASRQMLNMVNEQKFPPCPAVELEIELIKSEVRAVLNKVFELGNGDIARGTVLAFEA
GVLDVPFAPAACNAGKILPVRDNTGAIRVLEAGAVPLPKDILDLHHDYVAERARCEGRQPTFQMVVDDINAVSHSKLIGR
P
>SEQF1516_EDU84329.1 succinate dehydrogenase, cytochrome b556 subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWALFMIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMW
GILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVVLSLLAGVLVW
>SEQF1516_EDU84330.1 methylaspartate mutase, S subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKATLVIGVIGADCHAVGNKVLDRVFSNHDFRVINLGVMVSQDEYIDAAIETGADAIVVSSIYGHGDIDCLGMRERCIE
RGLGDILLYVGGNLVVGKHDFADVETKFKEMGFDRVFAPSHDLEDVCQLMAHDINQRHDVDTRILEEAI
>SEQF1516_EDU84331.1 transporter, dicarboxylate/amino acid:cation family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKISLTTMILLALVLGMIIGVVLNNTASPETAKLYAQEISIFTTIFLRLIKMIIAPLVVSTLVVGIAKMGDAKALGRIF
SKTLFLFICASLLSIALGLITVNFFMPGTGINFVAHGAETTGVVAAEPFTLKVFISHAFPTSIVDAMAHNEILQIVVFSI
FLGCSLTAIGEKGSAIVHALDSLAHAMLKLTGYVMLFAPLTVFAAISALIAERGLAVMVSAGIFMGEFYFTMLLLWVLLI
GLAIVYVGPCIRRLTRALSEPALLAFTTSSSEAAFPGTLEKLEQFGVSPKIASFVLPIGYSFNLVGSMAYCSFATVFIAQ
ACNIHLSIGEQITMLLILMLTSKGMAGVPRASMVVIAATLNQFNIPEAGLILLMGVDPFLDMGRSATNVMSNAMGAAMVS
RWEGEHFGEGCRGKALKPNESNVALP
>SEQF1516_EDU84332.1 hypothetical protein ECH7EC4501_5045 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYLSRCLASIHPTLAKNIYETENLSDQKLLHIDCRSTNEIKINIFFGQQREGLIEINSDTVIFSILSSLIDSAISKFQH
QIPVNGSVNRELLYEDYTD
>SEQF1516_EDU84333.1 protein AbrB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVLQWGMLCVLSLLLSIGFLGLHLPAALLLGPMIAGIIFSMRGVTLQLPRSAFLAAQAILGCMIAQNLTGSILTTLEVN
WPIVLAILLVTLLSSAIVGWLLVRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRM
MLGDNAEAVNQHIVWFPPVSINLLLTILLAVVAGTVGCLLRLPSGTMLIPMLAGAVLQSGQLITIELPEWLLAMAYMAIG
WRIGLGFDKQILLRALRPLPQILLSIFALLAICAGMAWGLTRFMHIDFMTAYLATSPGGLDTVAVIAAGSNADMALIMAM
QPLRLFSILLTGPAIARFISTYAPKRTA
>SEQF1516_EDU84334.1 amino acid/peptide transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYNDTHAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVM
LGALLMAIGHVVLGASEIHPSFLYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGY
AQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLVLLVATPALITVLFWKEWSVYAL
IVATIIGLGVLAKIYRKAENQKQRKELRLIVTLTFFSMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFA
VMLCGVFLAWVVKESVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAELFIDPVAMS
QITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINYSINAYIEVFDQITWGALACVGVVLMIWLYQ
ALKFRNRALALES
>SEQF1516_EDU84335.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGAVFKDFLHFFVTPDALRLSGLRVMTCRPDKAFTPHPALVA
>SEQF1516_EDU84336.1 succinate dehydrogenase, hydrophobic membrane anchor protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELTYEVWIGFCASAFTKVFTLLALFSILIHAWIGMWQVL
TDYVKPLALRLMLQLVIVVALVVYVIYGFVVVWGV
>SEQF1516_EDU84337.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARSFKVLSPTAILGYGFPEESFRKAMAESPDLIAVDAGSSDPGPHYLGAGKPFTDRAGVKRDLRYMITAGVQNNIPVVI
GTAGGSGAAPHLEWCREIIHEIAREEHLSFSMALIPADVDKAIVHQALDNGKITALDFVPPLTHDAIDESTYIVAQMGIE
PFQRALKERAQVVLGGRAYDPACFAALPIMQGFDEGLALHCGKILECAAIAATPGSGSDCAMGIIDDNGFTLKTFNPKRK
FTETSAAAHTLYEKSDPYFLPGPGGVLNLKGCTFKAVNDGEVYVSGSKHEETPYALKLEGARRVGFRCLTIAGTRDPIMI
AGIDKIIDEVKTSVSRNLSLDDDSIRINFHLYGKNGVMGDHEPMQTAGHELGIVLDVVAPTQEIANSVCSLVRSTMLHYG
YENRIATAGNLAFPFSPSDIQGGPVYEFSIYHLIEANDALRFDFHIEQVTPEGVQA
>SEQF1516_EDU84338.1 deoxyribodipyrimidine photolyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTHLVWFRQDLRLHDNLALAAACRNSSARLLALYIATPRQWAAHNMSPRQAELINAQLNGLQIALAEKGIPLLFREVDD
FAASVEIVKQVCAENSVTHLFYNYQYEVNERARDVQVERTLRNVVCEGFDDSVILPPGAVMTGNHEMYKVFTPFKNAWLK
RLREGMPECVAAPKVRSSGSIKPAPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQNGAGEYEQQRDFPAVEGTSRLSA
SLATGGLSPRQCLHRLLAEQPQALDGGAGSVWLNELIWREFYRHLMTYYPSLCKHCPFIAWTDRVQWQSNPAHLQAWQEG
KTGYPIVDAAMRQLNSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTDAAPYFRIF
NPTTQGEKFDREGEFIRQWLPELRNVPGKSVHEPWKWAEKAGVKLDYPQPIVEHKEARVQTLAAYEAARKGK
>SEQF1516_EDU84339.1 succinate dehydrogenase, flavoprotein subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIG
DQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTI
FSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQ
FHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGK
EVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRL
GGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAM
AKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYL
PESESMTRRSVNMEPKLRPAFPPKIRTY
>SEQF1516_EDU84340.1 allophanate hydrolase, subunit 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQRARCYLIGETAVVLELEPPVTLASQKRIWRLAQRLVDMPNVVEAIPGMNNITVILRNPESLALDAIERLQRWWEESEA
LEPESRFIEIPVVYGGAGGPDLAVVAAHCGLSEKQVVELHSSVEYVVWFLGFQPGFPYLGSLPEQLHTPRRAEPRLLVPA
GSVGIGGPQTGVYPLATPGGWQLIGHTSLSLFDPARDEPILLRPGDSVRFVPQKEGVC
>SEQF1516_EDU84341.1 NIF3 family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNTELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTASQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKR
NRLKTLLANDINLYGWHLPLDAHPELGNNAQLAALLGITVMGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDT
GPEVVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHATERGGIRALSEWLNENTDLDVTF
IDIPNPA
>SEQF1516_EDU84342.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRGKIPKTELLVTFEVVARHESYTRAAEELALTQSAVFRQVSALEEFLRTPLFSHSKKRIFLNDTGKYYLGIVKETLNKL
ERDTNTIMTWQPTVQVIELAVNPTFSTHWLIPNLHEFTKLHPDIIVNIHSLANNGDFLNREYDAVIMRENFCAPWAEVEY
LFEEEILPVCSGSLLAMSDQKLSVAELLTELPLLHQSTRITGWEEWFALSGVSSPLVNNGPRFDLLSMLIAAVRSNLGVA
LLPRFAIQHDLDSGDMVIPCDVPIRTGNRFIMTWQEEKSDSPHLQQFREWLLAKSVVPQEM
>SEQF1516_EDU84343.1 putative glutamate mutase mutL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQIVSVDIGSTWTKAALFTREGDALTLVNHVLTPTTTHHLAKGFFSSLNQVLNVDNALPLLNSGEVALKYSSSAKGGLAV
AAMGLVPSITLETAKVTAHSAGAKIAQYYAYKLNRRDIQALEETQPDILLFTGGTDGGEESYGLNNARVLAESKLDCAII
YAGNRDIQDEVQEILGHKDLTIVDNVLPDLDHPNPVAARQAICDIFLKRIVKGKGLDVIVDKTGEEPMPTPWTVFELVKA
ISNVDHSWKEFMLIDMGGATTDVYSACANTLSPDTVLHGVPEPFVKRTVEGDLGMRVSAVVVGESAKELVNVNFAQQPAQ
LDAFYHYLRHLVAHPDYLPANAEEKYFDTVLAGLCVGYATERHAGTKKEVCTCVGNVDLQMGRDLTTVRKVVGSGGWLSR
ASQFDMHHWLKYRELNDDGKRILLPTEFEYYRDSRGLLPLLANVARVDPLAAARTSIQCLTL
>SEQF1516_EDU84344.1 endonuclease VIII [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKTYQSQLIGQHVTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDT
GEESQTTRVLRVKLQTADKTILLYSASDIEMLTPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLD
QAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLDIPRFSYATRGQVDENKHHGALFRFKVFHRDGELCER
CGGIIEKTTLSSRPFYWCPGCQH
>SEQF1516_EDU84345.1 citrate (Si)-synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFDPGFTSTASCESKITFIDGDEGILLHRGFPIDQLATD
SNYLEVCYILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREI
AAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQNASTSTVR
TAGSSGANPFACIAAGIASLWGPAHGGANEAALKMLEEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMR
ETCHEVLKELGTKDDLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGWIAHWSEMH
SDGMKIARPRQLYTGYEKRDFKSDVKH
>SEQF1516_EDU84346.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVALSKSTKAMFTAFRQVVPFVSQDRVFTPDIAASQKFLEGYAINQK
>SEQF1516_EDU84347.1 periplasmic pilus chaperone family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFVKGFPLILLVASMCSHGAVQPDRTRIIFNSKDKATSLRVENRSDKLPYLAYSWIENEKGEKSDEFLVALPPIQRLEP
KATSQVRIMKQAATAKLPTDRESLFYYNLREIPPVPEGSEGHAILQVAVQSRIKLFWRPAALRKKMGDHVEQQLQVSQQN
NQLTLKTPTGYYLTIAYLGRDEKGVLPGFKSTMVAPFSSVTTSTGSYSGKQFYLGYMDDYGALRMNTLSCQRQCRLQPVE
NKK
>SEQF1516_EDU84348.1 allophanate hydrolase, subunit 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKIIRAGMYTTVQDGGRHGFRQSGISHCGALDMPALRIANLLVGNDANAPALEITLGQLTVEFETDGWFALTGAGCEAR
LDDNAVWTGWRLPMKAGQRLTLKRPQHGMRSYLAVAGGIDVPPVMGSCSTDLKVGIGGLEGRLLKDGDRLPIGKAKRDFM
EAQGVKQLLWGNRIRALPGPEYHEFDRASQDAFWRSPWQLSSQSNRMGYRLQGQILKRTTDRELLSHGLLPGVVQVPHNG
QPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLGQPIHFVQCSLEEALKARQDQQRYFEQLAWRLHNEN
>SEQF1516_EDU84349.1 succinate-CoA ligase, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKD
SILEAIDAGIKLIITITEGIPTLDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYE
AVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEAAAYIKEHVTKPVVGYIAGVTAP
KGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRSLADIGEALKTVLK
>SEQF1516_EDU84350.1 methylaspartate ammonia-lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKQALFTAGYSSFYFDDQQAIKNGAGHDGFFYTGEPVTQGFNAVRQAGECVSVQLILENGAVAVGDCTAVQYSGAGGR
DPLFLAEHFIPFLNDHIKPLLVGRDVDAFLPNARFFDKLRIDGNLLHTAVRYGLSQALLDATALATGRLKTEVVCDEWQL
PRVAESIPLFGQSGDDRYIAVDKMILKGIDVLPHALINNVEEKLGFKGEKLREYVRWLSDRILSKRTSARYHPTLHIDVY
GTIGLIFDMDPLRCAQYIASLEKEAQGLPLYIEGPVDAGNKPDQIRLLTAITKELTRLGSGVKIVADEWCNTYQDIVDFT
DAASCHMVQIKTPDLGSIHNIVDAVLYCNSHSMEAYQGGTCNETDVSARTCVHVALAARPMRMLVKPGMGFDEGLDIVFN
EMNRTIALLQAKD
>SEQF1516_EDU84351.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLETFRGREAGTQKPQQDTHCNKGDHTGNAMENGRYRRDGEPDGL
>SEQF1516_EDU84352.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQQRFDDSTLIRIFALHELHRLKEHGLTRGALLDYHSRYKLVFLAHSQPEYRKLGPFVADIHQWQNLDDFYNQYRQRVI
VLLSHPANPRDHTNVLMHVQGYFRPHIESTERQQLAALIDSYRRGEQPLLAPLMRIKHYMALYPYAWLSGQRYFELWPRV
INLRHSGVL
>SEQF1516_EDU84353.1 dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDKVVLEVPASADGILDAVLEDEGTTVTSRQILGRLREG
NSAGKETSAKSEEKASTPAQRQQASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAP
AAAAPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVK
AVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGN
FTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTR
LLLDV
>SEQF1516_EDU84354.1 hydro-lyase, Fe-S type, tartrate/fumarate family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKPFIWQEPFLQNKDGTEYTLISDQHITVTELDGEEVIKIAPEALTLLARQAFYEASFFLRSAHLQQVASILNDQQASS
NDKYVALQLLRNAEVSAKGVLPNCQDTGTATIVASKGQQIWTGGNDAEALSKGIYSTFQENNLRFSQNAPLDMYTEVNTQ
TNLPAQIDISAVAGDEYHFLCVNKGGGSANKAALYQETKSLLQPEKLTAFLIEKMKSLGTAACPPYHIAFVVGGLSADQT
LKIAKLASTKYYDNLPTSGNEQGQAFRDIELEKVLLEASQQFGIGAQFGGKYFAHDIRVIRLPRHGGSCPIAMALSCSAD
RNIKAKINKHGIWLEKLEHNPGQYIPASLREENHAQHVQLDLNRPLRDVMQDLARLPVGTRVSLSGPIVVARDIAHAKIK
ARLDSGEPMPEYLKHHIVYYAGPAKTPENMACGSLGPTTGGRMDGYIDTFQAAGGSLVMLSKGNRSQQVTDACHKHGGFN
LGSIGGAAALLAQEYVKSLRCLEYPELGMEAVWMMEVENLPAFILVDDKGNNFFSQFEQQHRCASCPAGH
>SEQF1516_EDU84355.1 succinate dehydrogenase, iron-sulfur subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLEFSIYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALIQLKEKDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPIS
ALNQPGKKIVIRPLPGLPVIRDLVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCP
SFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPKGLNPTRAIGHIKSMLLQRNA
>SEQF1516_EDU84356.1 cob(I)yrinic acid a,c-diamide adenosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEARISTERHVQRQQKLKEQVDTRVAAAIEKKGILIVFTGNGKGKSTAAFGTVTRAVGHGKTVGVAQYIKGQWDNGEYNL
LQPLGVEFHIMGTGFTWETQNRQADIDAAKEVWSESKRMLADKRYDLVVLDELTYMLAYHYLDTEEVIASLQNRPAQQSV
IVTGRGCHSQILKMADTVSEIRPVKHAFDNGIQAQPGIDW
>SEQF1516_EDU84357.1 LamB/YcsF family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIDLNADLGEGCTSDAELLTLVSSANIACGFHAGDAQTMQACVREAIKNGVAIGAHPSFPDRKNFGRSAMQLPPETVYA
QTLYQIGALATITRAQGGVMRHVKPHGMLYNQAAKEAQLADAIARAVYACDPALVLVGLAGSELIRAGKQYGLTTREEVF
ADRGYQADGSLVPRSQSGALIEDEEQALAQTLEMVQHGRVKSITGEWATVTAQTVCLHGDGEHALAFARRLRSAFAEKGI
VVAA
>SEQF1516_EDU84358.1 hypothetical protein ECH7EC4501_5046 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIAAILDPHRIVVGIDTLYTTQRETFTSESQQLIESALQTLHVMNLNNLETNRDEESHYLAFEYNVDTSDRITVSAYNEK
KPGCYGQCLVIQDDETDLFNLIKIKIFEARHNYVAQLMSDPEFMFKFSYSAQQNRLEPHLLVPAYFPLKTNEPVTQEDVL
LLYRFFKMNDDFNKLTSDEYMSILTPLMKCERSVHDNNRYVTGKDTLLLDYPPSGNQIHFHVFPDESATLVLYFSNNDIE
CFVFERDIPSQYRFFKMFTNLALVIDQLTEANKIL
>SEQF1516_EDU84359.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFAKGVLLAICLIFLPLKAALALNCYFGTANGAVEKSEAIMPFAVPANSKPGDKIWESDDIKIPVYCDNNTNGNFESEH
VYAWVNPYPGIQDPYYQLGVTYEGVDYDASLGKSRIDTNQCIDSKNIDIYTPEQIIAMGWQNKLCSGDPTVMHKSRTFVA
RMRLYVKVRAMPPHDYQSKLSDYIVVQFDGAGSVNEDPTAKNLKYHITGLENIRVLDCSVNFAISPETQVVDFGRFNVLD
IRRHTMSQQFKITTTKSQNDQCTDGFKVSSSFYTDETLIDEDKSLLIGNGLKLRLLDENASPYTFNKYSEYADFTSDLLV
YEKTYTAELSSTPGTPIDVGPFDTVVLFKINYN
>SEQF1516_EDU84360.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQSIVSLAQVIRSKNAGPYELVLDILFKTKENYERVKSSGQLTPELIARLYHVEPDFIHRIVWFDPSNAVKIVMPRDII
SGNVGDNDVYGAQQHAPLLNMSFDL
>SEQF1516_EDU84361.1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLRAGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQE
DVSALREVGKLLAFLKEPEPPKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLIT
WGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPISVALGADPATILGAVTPVPDTLS
EYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGYIEQGEMAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHST
YTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIV
CDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSKMGLDATNKWPGETQREWGRPIKKDPDVVAH
IDAIWDELAIFNNGKSA
>SEQF1516_EDU84362.1 CyaX protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFTVVHCCILFLSDGGSIAAWGQGFKVCTSAAALRHDSSVTGIMMSLCSERFVSSLGRSYTTPFPVSGKHYDQVYRASI
LTLTELKKPTNKPHCDSA
>SEQF1516_EDU84363.1 RarD protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDAKQTRQGVLLALAAYFIWGIAPAYFKLIYYVPADEILTHRVIWSFFFMVVLMSICRQWSYLKTLIQTPQKIFMLAVSA
VLIGGNWLLFIWAVNNHHMLEASLGYFINPLVNIVLGMIFLGERFRRMQWLAVILAICGVLVQLWTFGSLPIIALGLAFS
FAFYGLVRKKIAVEAQTGMLIETMWLLPVAAIYLFAIADSSTSHMGQNPMSLNLLLIAAGIVTTVPLLCFTAAATRLRLS
TLGFFQYIGPTLMFLLAVTFYGEKPGADKMVTFTFIWVALAIFVMDAIYTQRRKS
>SEQF1516_EDU84364.1 NAD(P)H-flavin reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDERDKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDR
ILKDHQIVVDIPHGEAWLRDDEERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHP
GLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSERNAREDRLFGDAFAFI
>SEQF1516_EDU84365.1 hypothetical protein ECH7EC4501_3077 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIVNNKILNLPIRKLFPTPIASSYGMNFEFMPELKWSFGYPGAIIFMILAGLAPYLYFKRKNWL
>SEQF1516_EDU84366.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDSQVNQQPCRNVHIIHNAQRSGVYLGCAVVPHKVANPGSHHAKKHQNAPLQRGLRHFLRISQQEPCNYRHQERAKIEP
RKGVMLRHRASFHQAFVTHHADGKSDIGELHQQQASPEMVGDLIIANNPGTNHRQQGTKSISPAQTALTHDVINQRDVER
RQYGEQQQFGNRQVEISAETQHIHHAELHRAHQHIQADCFQAIATGTQKRQKNECRQANAHQHRKIAIDVPRKVLAIKAK
GEGPQNRGDDK
>SEQF1516_EDU84367.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAHRLLIGKGMITLNLKRIFLALTLLPLFAVAADDCALSDPTLTVQAYTVNPQTERVKMYWQKANGEAWGTLHALLADMN
SQGQVQMAMNGGIYDESYAPLGLYIENGQQKVALNLASGEGNFFIRPGGVFYVAGDKVGIVRLDAFKTSKEIQFAVQSGP
MLMENSVINPRIHPNVASRKIRNGVGINKHGNAVFLLSQQATNFYDFACYAKAKLNVEQLLYLDGTISHMYMKGGAIPWQ
RYPFVTMISVERKG
>SEQF1516_EDU84368.1 DNA recombination protein RmuC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFSIMVYAVIALVGVAIGWLFASYQHAQQKAEQLAEREEMVAELSAAKQQITQSEHWRAECELLNNEVRSLQSINTSLE
ADLREVTTRMEAAQQHADDKIRQMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLSPLREQLDGFRRQVQDSF
GKEAQERHTLTHEIRNLQQLNAQMAQEAINLTRALKGDNKTQGNWGEVVLTRVLEASGLREGYEYETQVSIENDARSRMQ
PDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYTRESALQEHIASVRNHIRLLGRKDYQQLPGLRTLDYVLMFIPVEPA
FLLALDRQPELITEALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQQIADRASKLYDKMRLFIDDMSAIGQSLDKAQ
DNYRQAMKKLSSGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVSQDEEYRLRSVPEQPNDEAYQRDDEYNQQSR
>SEQF1516_EDU84369.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNVFKALTVLLTLFSLTGCGLKGPLYFPPADKNAPPPTKPVETQTQSTVPDKNDRATGDGPSQVNY
>SEQF1516_EDU84370.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQPGEELQETLTELDDRVVVDYLIKNPEFFIRNARAVEAIRVPHPVRGTVSLVEWHMARARNHIHVLEENMALLMEQAI
ANEGLFYRLLYLQRSLTAASSLDDMLMRFHRWARDLGLAGASLRLFPDRWRLGAPSNHTHLALSRQSFEPLRIQRLGQEQ
HYLGPLNGPELLVVLPEAKAVGSVAMSMLGSDADLGVVLFTSRDASHYQQGQGTQLLHEIALMLPELLERWIERV
>SEQF1516_EDU84371.1 transcriptional regulator MetR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRLGFRLFVRKSQPLRFTPQGEILLQLANQVLPQISQAL
QACNEPQQTRLRIAIECHSCIQWLTPALENFHKNWPQVEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFD
YEVRLVLAPDHPLAAKTRITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSLKSVDNTLLLIQMVAARMGIAALPHW
VVESFERQGLVVTKTLGEGLWSRLYAAVRDGEQRQPVTEAFIRSARNHACDHLPFVKSAERPTYDAPTVRPGSPARL
>SEQF1516_EDU84372.1 acetyl-CoA C-acyltransferase FadA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPH
SVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGI
SREMQDAFAARSHARAWAATQSGAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEALATLRPAFDPVNGTVTAGTSSA
LSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCDPSIMGYGPVPASKLALKKAGLSVSDIGVFEMNEAFAAQILPCIK
DLGLIEQIDEKINLNGGAIALGHPLGCSGARISTTLLNLMEHKDVQFGLATMCIGLGQGIATVFERV
>SEQF1516_EDU84373.1 twin arginine-targeting protein translocase TatC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHLVSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSL
ILSAPVILYQVWAFIAPALYKHERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMA
LFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLLAIPMYCLFEIGVFFSRFYVGKG
RNREEENDAEAESEKTEE
>SEQF1516_EDU84374.1 uridine phosphorylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKLASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEE
LAQLGIRTFLRIGTTGAIQPHINVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSD
TFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAGVIVNRTQQEIPNAETMKQTESQ
AVKIVVEAARRLL
>SEQF1516_EDU84375.1 hypothetical protein ECH7EC4501_3078 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNIHATLSWTLNDSHLTPSIAAEIIEKSVKPNEINTK
>SEQF1516_EDU84376.1 deoxyribonuclease TatD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDIGVNLTSSQFAKDRDDVVARAFDAGVNGLLITGTNLRESQQAQKLARQYSSCWSTAGVHPHDSSQWQAATEEAIIEL
AAQPEVVAIGECGLDFNRNFSTPEEQERAFVAQLRIAADLNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREE
MQACVAHGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSSRRNEPAHLPHILQRIAHWRGED
AAWLAATTDANVKTLFGIAF
>SEQF1516_EDU84377.1 HAD-superfamily hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFYRPLGRISALTFDLDDTLYDNRPVILRTEQEALTFVQNYHPALRSFQNEDLQRLRQAVREAEPEIYHDVTRWRFRSI
EQAMLDAGLSAEEASAGAHAAMINFAKWRSRIDVPQQTHDTLKQLAKKWPLVAITNGNAQPELFGLGDYFEFVLRAGPHG
RSKPFSDMYFLAAEKLNVPIGEILHVGDDLTTDVGGAIRSGMQACWIRPENGDLMQTWDSRLLPHLEISRLASLTSLI
>SEQF1516_EDU84378.1 thioesterase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAVLTAEQALKLVGEMFVYHMPFNRALGMELERYEKEFAQLAFKNQPMMVGNWAQSILHGGVIASALDVAAGLVCVGST
LTRHETISEDELRQRLSRMGTIDLRVDYLRPGRGERFTATSSLLRAGNKVAVARVELHNEEQLYIASATATYMVG
>SEQF1516_EDU84379.1 ATP-dependent DNA helicase RecQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCLVVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLM
KDQVDQLQANGVAAACLNSTQTREQQLEVMTGCRTGQIRLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDF
RPEYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLMEKFKPLDQLMRYVQEQRGKS
GIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIE
SYYQETGRAGRDGLPAEAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEGRQEPCG
NCDICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDYGHDKLKVYGMGRDKSHEHWVSVIRQLIH
LGLVTQNIAQHSALQLTEAARPVLRGESSLQLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVF
NDATLIEMAEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE
>SEQF1516_EDU84380.1 diaminopimelate epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQLLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCF
ARFVRLKGLTNKRDIRVSTANGRMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHC
VIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACGSGACAAVAVGIQQGLLAEEVRV
ELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL
>SEQF1516_EDU84381.1 uroporphyrinogen-III synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGRQLPQLADQLAALGESDLLFALSQHAVAFAQSQLHQQDRKWPR
LPNYFAIGRTTALALHTVSGQKILYPQDREISEVLLQLPELQNIAGKRALILRGNGGRELIGDTLTARGAEVTFCECYQR
CAIHYDGAEEAMRWQSREVTTVVVTSGEMLQQLWSLIPQWYREHWLLHCRLLVVSERLAKLARELGWQDIKVADNADNDA
LLRALQ
>SEQF1516_EDU84382.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESWLIPAAPVTVVEEIKKSRFITLLAHTDGVEAAKAFVESVRAEHPDARHHCVAWVAGAPDDSQQLGFSDDGEPAGTAG
KPMLAQLMGSGVGEITAVVVRYYGGILLGTGGLVKAYGGGVNQALRQLTTQRKTPLTEYTLQCEYSQLTGIEALLGQCDG
KIINSDYQAFVLLRVALPAAKVAEFSAKLADFSRGSLQLLAIEE
>SEQF1516_EDU84383.1 DNA helicase II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIAWLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGT
SQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ
SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIRLLAGDT
GKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISL
YCAFNELDEARFVVNRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDALSYLRLIAN
RNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDALAQETADMLLHVQ
TDRVIKDSGLRTMYEQEKGEKGQTRIENLEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLH
SAKGLEFPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKEVYHRPSRFIGELPEEC
VEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFGEGTIVNMEGSGEHSRLQVAFQGQGIKWLVAAYARLETV
>SEQF1516_EDU84384.1 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELRARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNV
PARHQNKDGSVDIDTLFRIGRGRAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPV
LLGPITWLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELPQAWLDAYKPAYDALQGQVKLLL
TTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVVELHKRLPSDWLLSAGLINGRNVWRADLTEKYVQIKDIVGKRDLWVA
SSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCHELALLCDALNSGDTAALAEWSAPIQARRHSTRVHNPAVEKRLAAIT
AQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKGNLDANNYRTGIAEHIRQAIVEQERLGLDVL
VHGEAERNDMVEYFGEHLDGFVFTQNGWVQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSMTDKPVKGMLTGPVTILC
WSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEAFRINAAVAKDDTQIHT
HMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERL
WVNPDCGLKTRGWPETRAALANMVQAAQNLRRG
>SEQF1516_EDU84385.1 iron donor protein CyaY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFENGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWIC
DRSGETFRDLLEQAATQQAGETVSFR
>SEQF1516_EDU84386.1 transcriptional activator RfaH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSWYLLYCKRGQLQRAQEHLERQAVNCLAPMITLEKIVRGKRTAVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVR
FGASPAIVPSAVIHQLSVYKPKDIVDPATPYPGDKVIITEGAFEGFQAIFTEPDGEARSMLLLNLINKEIKHSVKNTEFR
KL
>SEQF1516_EDU84387.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNTLLPSINIPCTLFETISLFDNYSADDMQYGDMVEQDFLSLGLSDISAKVDPYRLIKYHFPGPGSINVAFSASSSGTK
ISQRECTDILFAEMKELAKMFSFFGQYKTLIEDLIEHFRYGNGSNFHSQQLNLSFHEKINKYGYNSPIRIIKECIENGIN
STPSTGYQPLILQSIKTKLLSSRLNKFNDFEDSFNGLGISVHDISAQKISLLSFQKYAIGWSATIHFVAQDHFGLDVTDI
KNKTYSKYRFFRIWFFLQRHKDFAFKPFFTNFNTIERIENYL
>SEQF1516_EDU84388.1 fatty oxidation complex, alpha subunit FadB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVP
EEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGA
DSALEIIAAGKDVGADQALKIGLVDGVVKAEKLIEGAMAILRQAINGDLDWKAKRQPKLEPLKLSKIEATMSFTIAKGMV
AQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLG
AGIMGGGIAYQSAWKGVPVIMKDINDKSLALGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFERVDVVVEAI
VENPKVKKAVLAETEQKVRPDTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAW
ASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGF
PQRMQKDYRDAIDALFDANRFGQKNGLGFWHYKEDSKGKPKKEEDAAVDDLLAEVSQPKRDFSEEEIIARMMIPMVNEVV
RCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPA
RPVGDLKTA
>SEQF1516_EDU84389.1 tyrosine recombinase XerC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENGLQNWQQCDAAMVRNFAVRSRRKGLGAASLALRLSAL
RSFFDWLVSQNELKANPAKGVSAPKTPRHLPKNIDVDDINRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHL
DLESGEVWVMGKGSKERRLPIGRNALSWIEHWLDLRDLFGSEDDALFLSKLGKRISARNVQKRFAEWGIKQGLNNHVHPH
KLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYTHLDFQHLASVYDAAHPRAKRGK
>SEQF1516_EDU84390.1 hydrolase, Cof family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQVVASDLDGTLLSPDHTLSPYAKEPLKLLTARGINFVFATGRHHVDVGQIRDNLEIKSYMITSNGARVHDLDGNLIFA
HNLDRDIASDLFGVVNDNPDIITNVYRDDEWFMNRHRPEEMRFFKEAVFKYALYEPGLLEPEGVSKVFFTCDSHEQLLPL
EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMNDAEMLSMAGKGCIMGSAHQRLKD
LHPELEVIGTNADDAVPHYLRKLYLS
>SEQF1516_EDU84391.1 Xaa-Pro dipeptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESLASLYKNHIATLQERTRDALTRFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKL
WFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRS
FKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQASEEM
RSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSE
EAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREG
QFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
>SEQF1516_EDU84392.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYTYSDAGNSVFLVVDHLPWTDSDKINWYLKHQNEIKNQHPLPEGSWHTWYVIDIGNGFTDYKKYIEGPYEDLYCFPTIK
SNDNCITKNYLMVINEYPYRNTHIGINDFTEYQLTQENKIEQVFNPHNFKKDNF
>SEQF1516_EDU84393.1 threonine efflux protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLGITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGL
YLCWMGYQMLRGALKKEAVSAPAPQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTARWGIFALIIVET
LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR
>SEQF1516_EDU84394.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPFKPLVTAGIESLLNTFLYRSPALKTARSRLLGKVLRVEVKGFSTSLILVFSERQVDVLGEWAGDADCTVIAYASVLPK
LRDRQQLAALIRSGELEVQGDIQVVQNFVALAGLAEFDPAELLAPYTGDIAAEGISKAMRGGAKFLHHGIKRQQRYVAEA
ITEEWRMAPGPLEVAWFAEETAAVERAVDALIKRLEKLEAK
>SEQF1516_EDU84395.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKTLATLFLLTCLGSSSAYADNALILQTDFSLKDGAVSAMKGVAFGVDHNLKIFDLTHEIPPYNIWEGAYRLYQTASYW
PQGSVFVSVVDPGVGTDRKSIVLKTKNGQYFVSPDNGTLTLVAESLGIESVREIDEKANRLKGSEKSYTFHGRDVYAYTG
ARLASGAITFEQVGPELPAKVVELSYQKAKATKGEVKGNIPILDIQYGNVWSNISDELLNQAGIKLNDTLCVTISEGSRQ
KYAGKMPYVASFGDVPEGQPMVYLNSLLNVSVALNMDNFAQKHQVASGADWNIDVKKCDK
>SEQF1516_EDU84396.1 2-polyprenylphenol 6-hydroxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWMPNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRD
LFPPHIADQLALLQDKVAPFDGKLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDIL
PVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRRNFEDSPMLYIPEVYPDYCSEGM
MVMERIYGIPVSDVAALEKNGTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKE
DKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQP
QLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAFKEKAPFWVEKMPELPELVYDSLRQGKYLQH
SVDKIARELQSNHVRQGQSRYFLGIGATLVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR
>SEQF1516_EDU84397.1 magnesium and cobalt transport protein CorA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQSELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFF
EDAEDHAGNSTVAFTIRDGRLFTLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQAREILRDIESLLPHNESLFQKVNFL
MQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSYGMNFEFMPELKWSFGYPGAIIFMILAGLAPYLYFKRKNWL
>SEQF1516_EDU84398.1 lysophospholipase L2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFQQQKDWETRENAFAAFTMGPLTDFWRQRDEAEFTGVDDIPVRFVRFRAQHHDRVVVICPGRIESYVKYAELAYDLFHL
GFDVLIIDHRGQGRSGRLLADPHLGHVNRFNDYVDDLAAFWQQEVQPGPWRKRYILAHSMGGAISTLFLQRHPGVCDAIA
LTAPMFGIVIRMPSFMARQILNWAEAHPRFRDGYAIGTGRWRALPFAINVLTHSRQRYRRNLRFYADDPTIRVGGPTYHW
VRESILAGEQVLAGAGDDATPTLLLQAEEERVVDNRIHDRFCELRTAAGHPVEGGRPLVIKGAYHEILFEKDAMRSVALH
AIVDFFNRHNSPSGNRSTEV
>SEQF1516_EDU84399.1 homoserine/homoserine lactone efflux protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIAGLQTGLAIHIVLVGVGLGTLFSRSVIAFEVLKWAGA
AYLIWLGIQQWRAAGAIDLKSLASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDII
VMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA
>SEQF1516_EDU84400.1 porphobilinogen deaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVTSMLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRA
DIAVHSMKDVPVEFPQGLGLVTICEREDPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTR
LSKLDNGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAALNHHETALRVTAERAMN
TRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGERRGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA
>SEQF1516_EDU84401.1 Trk system potassium uptake protein TrkH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVL
GSVGALPFIFSESPNLTITDAFFESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATIAIGGFSTHDASIGYFDSPTINT
IIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQFTLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAG
FTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGF
FSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSMNPVAKWILIANMLFGRLEVFTLLVLFTPTF
WRE
>SEQF1516_EDU84402.1 ubiquinone/menaquinone biosynthesis methyltransferase UbiE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAK
FSRLVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVL
KPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQDTLKAMMQDAGFESVDYYNLTA
GVVALHRGYKF
>SEQF1516_EDU84403.1 adenylate cyclase, class I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHYHHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELY
RGMSVQDPPKGELPITGVYTMGSTSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLESWAASLGVEVSFFLIDENR
FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTLYAQGVLTPNEWLDLGGLSSLSA
EEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYPNPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFT
RLDLVRRCFYLKVCEKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQSYRNLIRF
ARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLTFIYVPPGRANRSGWYLYNRAPNIESIISHQ
PLEYNRYLNKLVAWAWFNGLLTSRTRLYIKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEY
DPTAAFRNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTILGKMHQDAAPPDSVEVF
CYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVSGQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSV
QVETNHVKLPAVVDGFASEGIIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGSSF
INFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQDHDTPLLQQYFS
>SEQF1516_EDU84404.1 phospholipase A1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAE
NARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGY
NHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLKIGYHLGDAVLSAKGQYNWNTGY
GGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDLF
>SEQF1516_EDU84405.1 sec-independent protein translocase protein TatA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTED
AKRHDKEQV
>SEQF1516_EDU84406.1 hypothetical protein ECH7EC4501_3073 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWDFFILLATLTSTKKREVQLLFCGVLLRVDGKILLA
>SEQF1516_EDU84407.1 dienelactone hydrolase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATTQQSGFAPAASPLASTIVQTPDDAIVAGFTSIPSQGDNMPAYHARPKQSDGPLPVVIVVQEIFGVHEHIRDICRRLA
LEGYLAIAPELYFREGDPNDFADIPTLLSGLVAKVPDSQVLADLDHVASWASRNGGDVHRLMITGFCWGGRITWLYAAHN
PQLKAAVAWYGKLTGDKSLNSPKQPVDIATDLNAPVLGLYGGLDNSIPQESVETMRQALRAANAKAEIIVYPDAGHAFNA
DYRPSYHAASAEDGWQRMLEWFKQYGGKKSL
>SEQF1516_EDU84408.1 twin arginine-targeting protein translocase TatB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKA
SMDELRQAAESMKRSYVANDPEKASDEAHTIHNPVVKDNEAAHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKT
AAPSPSSSDKP
>SEQF1516_EDU84409.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGVKTFAGIHTKGGNMSDDISLVMEGALAVIAVVGVYCLVVFLMERLGN
>SEQF1516_EDU84410.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRVLCVVIIVLLVACGVLSLGLNHYRDNAITYKAQRDKKASELKLANVTITDMQVRQRDVAALDARYSRELADARAENE
TLRADVAAGRKRLRINANCPGSLRKAPITSGVDNATGPRLAEAAERDYFILRERLMAMQKQLEGAQEYIRTQCIP
>SEQF1516_EDU84411.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIIKNCLSLINNALNIQKTSYSLTKMEQAGKLLNRKITPENTPPMLLSYRNADLTQEKNITERVLSIFKIKRDFVAVRI
QNNQFTDLKNKKIQGHQNTVASVMDWYNPQKNALGITMGTPRKSADIAKEEHRNALNFMIMEKNTFHEKILNSNDNLQKS
YSKTEDSSWVAASVGSLLDKGAKVYPDTSCSLRLGEPFIFTLPESVRVDVDIYPLKK
>SEQF1516_EDU84412.1 major tail protein V [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDDDWQRLAKVKDLTPGEMTAESYDDNYLDDEDADWTATGQGQKSAGDTSFTLAWKPGEEGQKGLIGWFESGDVRAYKI
RFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGKPSVAEERSKITPVSAIKVTPTSGTVAKGKTTTLTVSFEPESA
TDKTFRAVSADPSKATISVKDMTITVNGVATGKVQIPVVSGNGQFAAVAEVTVTEAGAAG
>SEQF1516_EDU84413.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVKLRLTVAALLLFLVVMVDFTSRIMSVLADGVLVCGIMVLLWPVIKRNSLHNA
>SEQF1516_EDU84414.1 phage minor tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTFRWKVKPDMEVNSQPSVREVRFGDGYSQRMAAGLNADLKTYRVTLSVTREEARHLEAFLAEHGGWKAFLWKPPYAYR
QIKVTCAGWSARVGMLRVEFSAEFKQVVN
>SEQF1516_EDU84415.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNDFCDKYFEYYLQINEVVRMDGNITIEYEVYVRIVWAEKAKTR
>SEQF1516_EDU84416.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDRCRAGETWPPDLAEFVALISESGANPFGLTVDAVMEEYRRWRNESWRYDGSDKYPWPQPVLYHICLEMRSKGIERQMT
EGELKRLVERQLTKWAKHVGNGLSVPPVRRQLAAPKRPPGPTPIELLKQEYERRKAAGFV
>SEQF1516_EDU84417.1 head-tail preconnector protein GP5 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRNLSHIIAAAFNEPLLLEPAYARVFFCALGREMGAASLSVPQQQVQLDAPGMLAETDEYMAGGKRPARVYRVVNGIAV
LPVTGTLVHRLGGMRPFSGMTGYDGIVACLQQAMADSQVRGVLLDIDSPGGQAAGAFDCADMIYRLRQQKPVWALCNDTA
CSAAMLLASACSRRLVTQTSRIGSIGVMMSHVSYAGHLAQAGVDITLIYSGAHKVDGNQFEALPAEVRQNMQQRIDAARR
MFAEKVAMFTGLSVDAVTGTEAAVFEGQSGIDAGLADELVNASDAISVMATALNSNVRGGTMPQLTATEAAAQENQRVMG
ILTCQEAKGREQLATMLAGQQGMSVEQARAILAAAAPQQPVASTQSEADRIMACEEANGREQLAATLAAMPEMTVEKARP
ILAASPQADAGPSLRDQIMALDEAKGAEAQAEQLAACPGMTVESARAVLAAGSGKAEPVSASTTALFERIMANHSPAAVQ
GGVPQTSADGDADVKMLMAMP
>SEQF1516_EDU84418.1 oxidoreductase, molybdopterin binding [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHADLLSWFKGNDRPPAPAGKALEFSKPAAWQNNLPLTP
ADKVSGYNNFYEFGLDKADPAANAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFP
LHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLTLMTVGVYGKALPPQNGAPVRLI
VPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYGFYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQ
VASLYRGLDLRENF
>SEQF1516_EDU84419.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVLLRPVLVPELGLVIVKPGRESMPVFHNTRVLVEPEPKSMRNLPSGVVPAVRQPLAEDKSLLPFFSDERVIRAAGGAG
ALSDWLLRHVKSCQWPHGDYHHSETVIHRYGTGAMVLCWHCDNQLRDQTSESLEQLAHQNLSAWMIDVIRHAMNGTQERE
LSLAELSWWAACNQVVDALPEAVARRSLGLPAEKIRSVYRESDIVPGEQTAISILKQRTKNIALPLHVHQQQNPPQKKTV
VSIAVDPESPESFMRRPKRCRWVNEKYTRWVKTQPCACCGKPADDPHHLIGHGQGGMGTKAHDIFTLPLCREHHNELHAD
PLEFEKKYGSQIELIFRFLDHAFATGVLG
>SEQF1516_EDU84420.1 hypothetical protein ECH7EC4501_3369 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELLLGEKGELIFTGFNVIFCGDTEKLLFLYTAVILRLTVGKSEETLLIMQITL
>SEQF1516_EDU84421.1 phage portal protein, lambda family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRTPVLIDVNGVPLRESLSYNGGGAGFGGQMAEWLPPAQSADAALLPALRLGNARADDLVRNNGIAANAVALHKDHIVG
HMFLISYRPNWRWLGMRETAAKSFVDEVEAAWSEYAEGMSGEIDVEGKRTFTEFIREGVGVHAFNGEIFVQPVWDTETTQ
LFRTRFKAVSPKRVDTPGHGMGNRFLRAGVEVDRYGRAVAYHICEDDFPRSGSGRWERIPRELPTGRPAMLHIFEPVEDG
QTRGANQFYSVMERLKMLDSLQATQLQSAIVKAMYAATIESDLDTEKAFEYIAGAPQGQKDNPLINILEKFSSWYDTNNV
TLGGVKIPHLFPGDDLKLQTAQDSDNGFSALEQALLRYIAAGLGVSYEQLSRDYSKVSYSSARASANESWRYFMGRRKFI
AARLATQMFSYWLEEALLRGIIRPPRARFDFYQARSAWSRAEWIGAGRMAIDGLKEVQESVMRIEAGLSTYEKEPALMGE
DYQDIFRQQVRESAERQKAGLSRPVWIAQAYQQQIAESRRPEEETTPRET
>SEQF1516_EDU84422.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METVFDALKALKKASSHEIAARLEISRDDAVTELWKLKRRGEADNKGSMWWLTSEATEAAPKTTAEMLINAIEQHGPQSA
DELALMFGITSRRANSSLAMAVSKGRLIRVNQDGKYRYCIPGDNLPAEPKAASVTETDGKAFPQPAGVALPVREAETQEE
IKTESVAVTVQSQSSFIRKHPDGLILPSLHVANRELRRAKGQVQKWERLCAALREINKHRDVIQKITTGDNG
>SEQF1516_EDU84423.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNGLELKAPVTDDVSRALAFAIKWVAVGIAVSPMLYGLAKLVIALKS
>SEQF1516_EDU84424.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU84425.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANAWLRLWHDMPNDPKWRTIARVSGQPIATVMAVYIHLLVSASRNVTTCHGVSLRGHIDVTTEDLASALDVTEDVIDSI
LHAMQGRVLDGDLISGWEKRQVMKEDNGNVSQTAKSPAERKRAQRERERLRKQNTDCHDESRRVTHMSRQITTDTDTDKE
LNPTHNARMRESATTGELNDASLQTAEPEYLDGLSEPIGKFPMTGVWQPSPDFRQRAAVWGMALPEPEFTPAELAAFRDY
WMAEGKVFTQVQWEQKFARHVQHVRAQVKPVSKGVSHAAPGGTASRAVQEIRAAREQWERENGFISNGNGLEAVGTYGGG
VFEPLDPEERGCAVEALDCSDWRDD
>SEQF1516_EDU84426.1 heavy metal sensor histidine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTTLINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDIL
IIHGDGINKIVNRTNVSDDMLNNIPASETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
SIIICIVAIILCSVLSPLLIRTGLREIKKLSGVTEALNYNDSREPVEVSALPRELKPLGQALNKMHHALVKDFERLSQFA
DDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIAGNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLL
DYLEYLSDEKEICFKVECNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDTNSYLNIDIASPGAKINEPEKLF
RRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLNKHNVFRITLPQRN
>SEQF1516_EDU84427.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKHEHIRMAINAWAYPDGEKVPAAEIARTYFELGMTFPELYDDSHPEALARNTQKIFRWLDKDTPDAVEKIQALLPAI
EKAMPPLLVARMRSHSSEYYREIVERRDRLVKDVDDFVAAAIAWGTLTNSGGQPGNAVVVH
>SEQF1516_EDU84428.1 crossover junction endodeoxyribonuclease RusA homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIDLVLPYPPTVNTYWRRRGSTYFVSKAGERYRRAVALIVRQQRLKLSLSGRLAIKIIAEPPDKRRRDLDNILKAPLDA
LTHAGLLMDDEQFDEINIVRGQLVPGERLGIKITELECA
>SEQF1516_EDU84429.1 putative metal-dependent phosphohydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLQHWQAQFENWLKNHHQHQDAAHDVCHFRRVWATAQKLAADDDVDMLVILTACYFHDIVSLAKNHPQRQSSSILAAEE
TRRLLREEFVQFPAEKIEAVCHAIAAHSFSAQIAPLTTEAKIVQDADRLEALGAIGLARVFAVSGALGVALFDAEDPLAQ
HRPLDDKRYALDHFQTKLLKLPQIMQTVRGKQLAQHNAHFLVEFMAKLSAELAGENEGVDHKVIDAFSPAG
>SEQF1516_EDU84430.1 tir-cytoskeleton coupling protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLVQHLAEHGIQPARNMAEHIPPAPNWPAPPLPVQNEQSRPLPDVAQRL
VQHLAEHGIQPARSMAEHIPPAPNWPAPPPPVQNEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQ
NEQSRPLPDVAQRLMQHLAEHGIQPARNMAEHIPPAPNWPAPTPPVQNEQSRPLPDVAQRLMQHLAEHGINTSKRS
>SEQF1516_EDU84431.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDMLNLGNNESLVCGVFPNHDGTFTAMTYTRSKTFKTEAGAHRWLARNAN
>SEQF1516_EDU84432.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVIKEMPVERNEYGCWTHPEYEKFCDGREYISTEEFNAWMEKNNLQWAIRSMDEDDFNLDADGPDISAWEPERPEGEGW
FIGSIHDTEDGPVCVWLRNKAEA
>SEQF1516_EDU84433.1 chaperone protein HchA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKPYRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLL
PLYHLHAAGFEFEVATISGLMTKFEYWAMPQKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIG
LPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGM
NIINDDITGRVHKDRKLLTGDSPFAANALGKLAAQEMLAAYAG
>SEQF1516_EDU84434.1 phage tail assembly protein T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAGMTSTEYADWHRFYRTHYFQDTQLDMHFSGLTYAVLSLFFCDPDMHPSDFSLLVPRHEEEQVERPDEDKMLMQKAAG
LAGGVRFGGDGGRDILSSADVADVMVDDAALMMASAGIPGGVRYVPAGW
>SEQF1516_EDU84435.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTELTKEWLQNTITGIESSRDEIPFGLDEDQNNMLTALKIALASLASVSDERAAYELFMEKRFGESVDRRRAKNGDREYM
AWDMALGWIIWCHRAAMLQAGNFRENKGSSTNNFRIISETSTNSPAIPDEVLSAILKVARLRADFDASEVDRRGIGSCLD
EAEQELIVTINEYASQIAVEATQGENQ
>SEQF1516_EDU84436.1 YjhS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIKHYDVVRAASPSDLAEKLTHKLKEGWQPYGGPVAITPYTLMQAVAIEGEPQVGPSSEPDWYYVIVLAGQSNAMAYGE
GLPLPDSYDAPDPRIKQLARRSTVTPGGAACRYNDIIPADHCLHDVQDMSTLNHPRADLSKGQYGCVGQGLHIAKKLLPY
IPNNAGILLVPCCRGGSAFTQGAEGTFSESTGASQDSARWGVGKPLYQDLISRTKAALQKNPKNVLLAVCWMQGEFDMSA
ATHAQQPALFTAMLTQFRADLSVFNAQCHGGSAADVPWICGDTTYYWKNTYATQYDTVYGGYKNRESEGVYFVPFMTDGN
GVNTATNAPAEDPDIPASGYYGAASRTNGNQVSSNRPTHFSSWARRSIIPDRLATAILNAAGRTSAFISGKAPEIKPSPG
GNTPSGPSADTSVRTISLLPAAGEAAAQGWSIKDGGIQLSDGVFKITRQSNKTWSLTHPVDDAITLLTQGGRLTCKFRLS
GALTNNQFGLGIYLYTDAPVPDGVAMTGTGNPFLMSYFTQTTDGRVNLMHHRKAGNTKLGEFGDYGNDWQTLELVFTAGS
AMVTPKLNGVAGPAFQVIKDSLTLGLNALTLTDVTKNAAYGVEIESLMLEINAPAA
>SEQF1516_EDU84437.1 transthyretin family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKRYLVLSVVTAAFSLPSLVYAAQQNILSVHILNQQTGKPAADVTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTA
TTGDYRVVFKTGDYFKKQNLESFFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS
>SEQF1516_EDU84438.1 hypothetical bacteriophage protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRHLFSLLAQQVPVVQADGWIVNQNDQKKQNPPKRVKCGCVEDA
>SEQF1516_EDU84439.1 hypothetical protein ECH7EC4501_3362 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKINVMELFFRHQKSNAASLLRLQAIAGNVKSFRNFIPS
>SEQF1516_EDU84440.1 tail assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNISAEPEAYFRIAPEDWLQAEMQGEIVALVHSHPGGLPWLSEADRRLQIKSALPWWLVCRGEIHKFRCVPHLTGRRFEH
GVTDCYTLFRDAYHLAGITLPDFEREDDWWRNGQNLYLDNMAATGFYRVPLSSAQAGDILLCCFGASVANHAAIYCGNGE
LLHHLPEQLSKRERYSEKWQRRTHSVWRHRHWHASAFTGICNDLAAASACT
>SEQF1516_EDU84441.1 heavy metal response regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTYDLWHIIFMKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQILQTLRTAK
QTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQHHALNSTLEISGLRMDSVSQSVSRDNISITLTR
KEFQLLWLLASRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSFVAVKK
>SEQF1516_EDU84442.1 phage lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAKIRYGLSAAVLALIGAGASAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGAILVDGKPVVPGMKLSKEKCDQVNAI
ERDKALEWVERNIKVPLTEPQKAGIASFCPYNIGPGKCFPSTFYRRINAGDRRGACEAIRWWIKDGGRDCRIRSNNCYGQ
VSRRDQESALACWGIDR
>SEQF1516_EDU84443.1 IS629 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU84444.1 phage minor tail protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDIHEESLNESVKSEQSPRVVLWEIDLTAQGGERYFFCNELNEKGEAVTWQGRQYQAYPIDGSGFEMNGKGSSARPSLT
VSNLFGLVTGMAEDLQSLVGATVVRRRVYARFLDAVNFVAGNPEADPEQELTDRWVVEQMSSLTAMTASFVLATPTETDG
ALFPGRIMLANTCMWDYRGDECGYNGPAVADEFDNPTTDIRKDRCSKCMRGCEMRGMVANFGGFLSINKLSQ
>SEQF1516_EDU84445.1 gpW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTVAELQALRQARLDLLTGKRVVSVQKDGRRIEYTAASLDELNRAINDAESVLGTTRRRRRPLGVRL
>SEQF1516_EDU84446.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METLLPNVNTSEGCFDIGVLLSNKAFTEDAINMRKYEPYLLNDNSILSRIALIKLGIFGERQ
>SEQF1516_EDU84447.1 bacteriophage lambda tail assembly protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTAAEAIRALSLQMPGFRRQMNEGWYQIRIRGEDTAPEAVYARLHEPLGEGAVIHIVPRLAGAGKGGLQIVLGAAAIVG
SFFTAGASMALWGSALAAGGFSATTMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGKQNTYFSSLDNMIAQGNPMPVP
YGEMLVGSRRISQDISTRDEGGDGKVVVIGRG
>SEQF1516_EDU84448.1 phage terminase large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNISEQQLNNMMSAVTTALQPLIRALPVTPVEWADQNYYLPKESSYGEGEWKTLPFQIAIMNSMGNDQIRTVNLIKSARV
GYTKMLLGGGGYFIEHKSRNSLLFQPTDSAAEDFMKSHVEATIRNVPCLKDLSPWLGRKHRDNTLTLKRFSSGVGFWCLG
GAAAKNYREKSVDVVCYDELSSFEPDVEKEGSPTLLGDKRIEGSVWPKSIRGSTPKIKGTCQIEKAANESAHFMRFYVPC
PHCGEAQYLKFGDESTPFGLKWEKDSPESVFYLCEHHGCVIHQSELDQSNGRWICENTGMWTRDGLTFFSARGDEIPPPR
SIMFHIWTAYSPFTTWVQIVYDWLDALKDPNGLKTFVNTTLGETWEEAVGEKLDHQVLMDKVVRYTAAVPARVVYLTAGI
DSQRNRFEMYVWGWAPGEEAFLVDKIIIMGRPDEEETLLRVDAAINKKYRHADGTEMTISRVCWDTGGIDGEIVYQRSKK
HGVFRVLPVKGASVYGKPVITMPKTRNQRGVYLCEVGTDTAKEILYARMKADPSPADEATSYAIRFPDDPEIFSQTEAQQ
LVAEELVEKWEKGKMRLLWDNKKRRNEALDCLVYAYAALRVSVQRWQLDLAVLAKSREEETTRPTLKELAAKLSGGVNGY
SR
>SEQF1516_EDU84449.1 metal-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIRLHKLAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGVFDDANVQNRTLSDWDGVWQSVYPLLQSGKLAPVFQK
KADADKTKTFAEIKDYYHKGYATDIEMIGIEDGIVEFHRNNETTSCKYDYDGYKILTYKSGKKGVRYLFECKDPESKAPK
YIQFSDHIIAPRKSSHFHIFMGNDSQQSLLNEMENWPTYYPYQLSSEEVVEEMMSH
>SEQF1516_EDU84450.1 nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRFSKTQIYLHWITLLFVAITYAAMELRGWFPKGSSTYLLMRETHYNAGIFVWVLMFSRLIIKHRYSDPSIVPPPPAWQ
MKAASLMHIMLYITFLALPLLGIALMAYSGKSWSFLGFNVSPFVTPNSEIKALIKNIHETWANIGYFLIVAHAGAALFHH
YIQKDNTLLRMMPRRK
>SEQF1516_EDU84451.1 putative prophage tail fibre C-terminus family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNILKKLMQRLCGCGKHDDREHGELLTAQLRLGPADILESDENGIIPEQDRVITQVVILDADKKQIQCVVRPLQILRADG
TWENIGGMK
>SEQF1516_EDU84452.1 putative Prophage Qin DNA packaging protein NU1 homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATQTEVARHLSLTDRQLRRLQKLPGAPISNKRGQLDLDAWRDFYISYLRRSKNDVPDGDSEDDYEEKLLIARWELTAEQ
AVTQQLKNEVSKGKLIDTGFCIFALSKLAMALSSTLDSIPLSMQRQFPDLTPRHLDHLKTLIAKGANQCARAGDKLPDLL
DEYIRATTE
>SEQF1516_EDU84453.1 tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVKISGVLKDGTGKPVENCTIQLKARRNSATVVVNTVASENPDEAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYED
SQPGTLNDFLGAMSEDDVRPEALRRFELMVEEAARHAEEAKKNAGEAETSARNAGISASQAEESAANADTSAGDASESAR
QAAESAAAAKQSEEASSSSASAAAQKASESSQSAADAELSKKTAESAAGNAARDATTATEKARESAESAQSAEQSRIAAE
EAVNRIPTVVGPPGPKGEPGPAGPQGPKGDKGERGDTGPVGATGERGPAGDAGPAGPQGPKGDRGERGETGLTGNAGPQG
PKGDTGAAGPAGPQGPKGETGAAGPVGATGPQGPKGDPGETQIRFRLGPASIIETNSHGWFPGTDGALITGLTFLAPKDT
TRVQGFFQHLQVRFGDGPWQDVKGLDEVGSDTGRTGE
>SEQF1516_EDU84454.1 antitermination protein Q [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNHYLQFVRELLIIATADLSGATKGQLEAWQENAMFDTGRYRRKKIRYRDEVTGKMITRDNPPIPGKQSLAKVTSIPLV
SPVEFSTSSWRRAVLSLEEHHKAWLLWCYSGSICWEYQIAITQWAWNEFNTQSGTRKIAGKTQERLKKLIWLAAQAVKAE
LFGGEGYEYKELALLVGVTTKNWSKTFTRHWVAMKHIFHRLDSEALLFVMRTRSKQKAAFSKQSVAKVD
>SEQF1516_EDU84455.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKKYELGVKGINNYPDKITVTVAPEIGGYPSLLLPDVAISLDRTEGATLEFYEAEAKKQAKQFFMDVAAGLCEGDGPLP
EKRPVILEAQDVLITYRGKLPGIITGSLKTPPLA
>SEQF1516_EDU84456.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSDYLQTAILNLPSFNEITIKNKSQKNNKTTHKKTK
>SEQF1516_EDU84457.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSAFALVMTVFLITGESQNVITGIYASKESCLQARDEQKISGECLPVKKVSLYLNNETPAG
>SEQF1516_EDU84458.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEINYQELRVELGAAKKRIEELEANRVVLEVENERLKHAMAVALEHISVTDAGQAGVAAMIIYDAMYHSEKTDPYAFLA
ELRAQGVEMVREHPAIKLCSLTHICDELVAELRKGGNK
>SEQF1516_EDU84459.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKITTGVSYTTSAVGTGYWLLQLLDKVSPSQWVAIGVLGSLLFGLLTYLTNLYFKIREDRRKAARGE
>SEQF1516_EDU84460.1 hypothetical protein ECH7EC4501_3379 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNIQHQCSIIITYLHPPTTAFDILTQFSSLVKNSDQLSRKYSDYPN
>SEQF1516_EDU84461.1 phage minor tail protein G [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLKTEQFEYNGVSVTLSELSALQRIEHLALLKRRAEQAESSGNLQVSVEDLVRTGAFLVAMSLWHNHPQKTQSPSMNEA
VMKIEQEVLTTWPADAIARAEDVVLCLSGMSGAVRPDTDITEVAKNNTLTDDDFSAGKSSTAS
>SEQF1516_EDU84462.1 putative repressor protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQEKMMESLGFRLKRLRKDKGLTQVELGKLSGVTGVTIGYWEKDLNEPGSKALSKLAQALGTTESYLLYGVSSPELSFVQ
STSGTKIPYLSWGEAISFLILKGEKTMGNVDRITTFFDVEEGDFAVSMPDDTMHNPSGSPSIPVGATVILRPGESYKNGS
IVAVIVPDPLKNEPSMTIKKLVIDGKLVYLSPLNPRYQSSLLTPECKIVAVAKGVQFNL
>SEQF1516_EDU84463.1 major head protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGLFTTRQLLGYTEQKVKFRALFLELFFRRTVNFHTEEVMLDKITGKTPVAAYVSPVVEGKVLRHRGGETRVLRPGYVKP
KHEFPWSR
>SEQF1516_EDU84464.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEQINIALDQKGSGNFSAWVIEACRRRLINEKHAQFVPNKDKHDQSTCSDRFT
>SEQF1516_EDU84465.1 bacteriophage lambda head decoration protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTKNITEQRAEVRIFAGNDPAHTATGSSGISSATPALTPLMLDEASGKLVVWDGQKAGSAVGILVLPLEGTETVLTYYK
SGTFATEAIRWPESVDEHKKANAFAGSALSHAALP
>SEQF1516_EDU84466.1 enterobacterial Ail/Lom family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKLYAAILSAAICLAVSGAPAWASEQQATLSAGYLHARTSAPGSDNLNGINVKYRYEFTDTLGLVTSFSYAGDKNRQLT
RYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
GAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF
>SEQF1516_EDU84467.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLTAKQVTWLKVCLHLAGLLPFLWLVWAINHGGLGADPVKDIQHFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLL
GLWCFAWATLHLTSYALLELGVNNLALLGKELITRPYLTLGIISWIILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAIL
APIHYLWSVKIISPQPLIYAGLAVLLLALRYKKSRSLFNRLRKQVHNKLSV
>SEQF1516_EDU84468.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKISRQSTRDEPFGQVVFALLLVQKRWYCARSSIRWLTLREQRMECRPGCGACCTAPSISSPIPGMPDGKPANTPCIQL
DEQQRCKIFTSPLRPKVCAGLQASAEMCGNSRQQAMTWLIDLEMLTAP
>SEQF1516_EDU84469.1 Inosine-uridine preferring nucleoside hydrolase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKRKIILDCDPGHDDAIAIMMAAKHPAIDLLGITIVAGNQTLDKTLINGLNVCQKLEINVPVYAGMPQPIMRQQIVADN
IHGDTGLDGPVFEPLTRQAESTHAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFT
PSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSDIMNFTLKTQFENYGLAGGPVHD
ATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCDELGVLGKPANTKVGITIDSDWFWGLVEECVRGYIKTH
>SEQF1516_EDU84470.1 cytidine deaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSATGLDEDALAFALLPLAAACARTPLSNFNVGAIARGV
SGTWYFGANMEFIGATMQQTVHAEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDY
LADAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECKDGRIFSGSYAENAAFNPTLPPL
QGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDATSATLKALGCHNIDRVLLA
>SEQF1516_EDU84471.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNITLQKQHRTLWHFIPGLALSAVITGVALWGGSIPAVAGAGFSALTLAILLGMVLGNTIYPHIWKSCDGGVLFAKQYL
LRLGIILYGFRLTFSQIADVGISGIIIDVLTLSSTFLLACFLGQKVFGLDKHTSWLIGAGSSICGAAAVLATEPVVKAEA
SKVTVAVATVVIFGTVAIFLYPAIYPLMSQWFSPETFGIYIGSTVHEVAQVVAAGHAISPDAENAAVISKMLRVMMLAPF
LILLAARVKQLSGANSGEKSKITIPWFAILFIVVAIFNSFHLLPQSVVNMLVTLDTFLLAMAMAALGLTTHVSALKKAGA
KPLLMALVLFAWLIVGGGAINYVIQSVIA
>SEQF1516_EDU84472.1 fumarylacetoacetate hydrolase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQYVFEPQAPVTVPVVGSDEQFPVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADAVVPVAAGETLALPYPAQTDN
YHYEIELVVAIGKKGSDIPLEHAHEYVWGYATGLDMTRRDRQMEMRQMGRPWEIGKAFDLSAPIAPLHKARDIGGIDNAP
IWLQVNGEDHQRSDIRHLIWSVNETICYLSGFFELQPGDLIFTGTPEGVGPVVKGDVITGNVEGLTPIAVKIV
>SEQF1516_EDU84473.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQRRDLQALIDAAPVGKMQWRVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLTAGDLAPLFGAGLLGLTAGALLCGPL
SDRFGRKRVIELCVFLFGALSLASAFSPDLQTLVFLRFLTGLGLGGAMPNTITMTSEYLPARRRGALVTLMFCGFTLGSA
FGGIVSAQLVPVIGWHGILVLGGVLPLMLFVALLVVLPESPRWQVRRQLPQAVIAKTVSAITRERYVDTHFYLIESASVT
KGSIRQLFMGRQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTLGALALGVLMDKFNPFR
VLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGLNALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGG
VMMAMNFSFDTLFFIIAVPAAISAVMLTLLITVVRQSTSVPDSLPRAGVVNE
>SEQF1516_EDU84474.1 sugar efflux transporter B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHNSPAVSSAKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTDEVHARPAMVGFFFTGSAVIGVLVSQFLAGRSDKRGD
RKSLIVFCCLLGVLACTLFAWNRNYFVLLFVGVFLSSFGSTANPQMFALAREHADKTGREAVMFSSFLRAQVSLAWVIGP
PLAYALAMGFSFTVMYLSAAVAFIVCGVMVWLFLPSMQKELPLATGTVEAPRRNRRDTLLLFVICTLMWGSNSLYIINMP
LFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFAKRLGKRFLMRVAAVGGVCFYAGMLMAHSPVILLGLQLLNAIFIG
ILGGIGMLYFQDLMPGQAGSATTLYTNTSRVGWIIAGSVAGIVAEIWNYHAVFWFAMVMIIATLFCLLRIKDV
>SEQF1516_EDU84475.1 PTS system, fructose-specific, IIBC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTLLIIDANLGQARAYMAKTLLGAAARKAKLEIIDNPNDAEMAIVLGDSIPNDSALNGKNVWLGDISRAVAHPELFLSE
AKGHAKPYTALVAATAPVAASGPKRVVAVTACPTGVAHTFMAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAAAD
LVIVAADIEVDLAKFAGKPMYRTSTGLALKKTAQELDKAVAEATPYEPAGKAQTATSEGKNESAGAYRHLLTGVSYMLPM
VVAGGLCIALSFAFGIEAFKEPGTLAAALMQIGGGSAFALMVPVLAGYIAFSIADRPGLTPGLIGGMLAVSTGSGFIGGI
IAGFLAGYIAKLISTQLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGILEGLTHWLQTMGTANAVLLGAILGG
MMCTDMGGPVNKAAYAFGVGLLSTQTYGPMAAIMAAGMVPPLAMGLATMVARRKFDKAQQEGGKAALVLGLCFISEGAIP
FAARDPMRVLPCCIVGGALTGAISMAIGAKLMAPHGGLFVLLIPGAITPVLGYLVAIIAGTLVAGLAYAFLKRPEVDAVA
KAA
>SEQF1516_EDU84476.1 galactose ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYKKDSGTILFQGKEIDFH
SAKEALENGISMVHQELNLVLQRSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDEVTVLRDGQWIATEPLAGLTMDK
IIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQPSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTI
TLHGKKINNHNANEAINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDSMRVKTPGH
RTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIAELAKKGKGIIIISSEMPELLGITDRILVMS
NGLVSGIVDTKTTTQNEILRLASLHL
>SEQF1516_EDU84477.1 CobW/P47K family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRTNLITGFLGSGKTTSILHLLAHKDPNEKWAVLVNEFGEVGIDGALLADSGALLKEIPGGCMCCVNGLPMQVGLNTLL
RQGKPDRLLIEPTGLGHPKQILDLLTAPVYEPWIDLRATLCILDPRLLLDEKSASNENFRDQLAAADIIVANKSDRATPE
SEQALQRWWQQNGGDRQLIHSEHGKVAGHLLDLPRHNLAELPASAAHSHQHVVKKGLAALSLPEHQRWRRSLNSGQGHQA
CGWIFDADTVFDTIGILEWARLAPVERVKGVLRIPEGLVRINRQGDDLHIETQNVAPPDSRIELISSSEADWNALQSALL
KLRLATTA
>SEQF1516_EDU84478.1 nucleoside transporter, NupC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDVMRSVLGMVVLLTIAFLLSVNKKKISLRTVGAALVLQVVIGGIMLWLPPGRWVAEKVAFGVHKVMAYSDAGSAFIFGS
LVGPKMDTLFDGAGFIFGFRVLPAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAI
VKPFIDRLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFARLLSPATESSQVSFNNLSFTETP
PKSIIEAAATGAMTGLKIAAGVATVVMAFVAIIALINGIIGGVGGWFGFEHASLESIVGYLLAPLAWVMGVDWSDANLAG
SLIGQKLAINEFVAYLNFSPYLQTAGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGLRALAAATL
SNLMSATIAGFFIGLA
>SEQF1516_EDU84479.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQTLLAIEDLSVGFRHQQTVRTVVNDVSLQIEAGETLALVGESGSGKSVTALSILRLLPSPPVEYLSGDIRFHGESLLH
ASDQTLRGVRGNKIAMIFQEPMVSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGG
ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQGELNMGMLFITHNLSIVRKLAHRVAVMQNGRCVEQNY
AATLFASPTHPYTQKLLNSEPSGDPVPLPEPASTLLDVEQLQVAFPIRKGILKRIVDHNVVVKNISFTLRAGETLGLVGE
SGSGKSTTGLALLRLINSQGSIIFDGQPLQNLNRRQLLPIRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVHQPTLSAAQ
REQQVIDVMHEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTSSLDKTVQAQILTLLKSLQQKHQLAYL
FISHDLHVVRALCHQVIVLRQGEVVEQGPCARVFATPQQEYTRQLLALS
>SEQF1516_EDU84480.1 hypothetical protein ECH7EC4501_2498 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRLTHNNQAVNQLNNFAPTQGGGVTPAGEIINAITQ
>SEQF1516_EDU84481.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLHNFLSFFLIADGKIRYQQFHFSSVSSQSATVKWHFDYSWRF
>SEQF1516_EDU84482.1 GTP cyclohydrolase I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHMTEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLD
YANFPKITLIENKMKVDEMVTVRDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQIL
IALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAVRHHN
>SEQF1516_EDU84483.1 ABC transporter, periplasmic solute-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVRILLLFIALFTFGAQAQAIKESYAFAVLGEPRYAFNFNHFDYVNPAAPKGGQITLSALGTFDNFNRYALRGNPGART
EQLYDTLFTTSDDEPGSYYPLIAESARYADDYSWVEVAINPRARFHDGSPITARDVEFTFQKFMTEGVPQFRLVYKGTTV
KAIAPLTVRIELAKPGKEDMLSLFSLPVFPEKYWKDHKLSDPLATPPLASGPYRITSWKMGQNIVYSRVKDYWAANLPVN
RGRWNFDTIRYDYYLDDNVAFEAFKAGAFDLRMENDAKNWATRYSGKNFDKKYIIKDEQKNESAQDTRWLAFNIQRPVFS
DRRVREAITLAFDFEWMNKALFYNAWSRTNSYFQNTEYAARNYPDAAELVLLAPMKKDLPPEVFTQIYQPPVSKGDGYDR
DNLLKADKLLNEAGWVLKGQQRVNATTGQPLSFELLLPASSNSQWVLPFQHSLQRLGINMDIRKVDHSQITNRMRSRDYD
MMPRLWRAMPWPSSDLQISWSSEYINSTYNAPGVQSPVIDSLINQIIAAQGNKEKLLPLGRALDRVLTWNYYMLPMWYMA
EDRLAWWDKFSQPAVRPVYSLGIDTWWYDVNKAAKLPSARQQGE
>SEQF1516_EDU84484.1 colicin I receptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRLNPFVRVGLCLSAISCAWPVLAVDDDGETMVVTASSVEQNLKDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLT
NEGDNRKGVSIRGLDSSYTLILVDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVVNIITKKI
GQKWSGTVTVDTTIQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDDPQNSTTTDTGETPRIEGFSSRDGNVE
FAWTPNQNHDFTAGYGFDRQDRDSDSLDKNRLERQNYSVSHNGRWDYGTSELKYYGEKVENKNPGNSSPITSESNTVDGK
YTLPLTAINQFLTVGGEWRHDKLSDAVNLTGGTSSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHETYGEHWSPRAYL
VYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGACKIVGSPDLKPETSESWELGLYYMGEEGWLEGVESSVTVFRN
DVKDRISISRTSDVNAAPGYQNFVGFTANGVPVFSYYNVNKARIQGVETELKIPFNDEWKLSLNYTYNDGRDVSNGENKP
LSDLPFHTANGTLDWKPLALEDWSFYVSGHYTGQKRADSATAKTPGGYTIWNSGAAWQVTKDVKLRAGVLNLGDKDLSRD
DYSYNEDGRRYFMAVDYRF
>SEQF1516_EDU84485.1 PTS system fructose-specific phosphotransferase enzyme IIA component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFQLSVQDIHPGEKAGDKEEAIRQVAAALVQAGNVAEGYVNGMLAREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQ
FPEGVTWGDGQVAYVAIGIAASSDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNEMLTLDIV
ASDLLTLQALNAARLKEAGAVDATFVTKAINEQPLNLGQGIWLSDSAEGNLRSAIAVSRAANAFDVDGETAAMLVSVAMN
DDQPIAVLKRLADLLLDNKADRLLKADAATLLALLTSDDAPTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSDITVT
NLDGTGKPANGRSLMKVVALGVKKGHRLRFTAQGADAEQALKAIGDAIAAGLGEGA
>SEQF1516_EDU84486.1 kinase, pfkB family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MREKDYVVIIGSANIDVAGYSHESLNYADSNPGKIKFTPGGVGRNIAQNLALLGNKAWLLSAVGSDFYGQSLLTQTNQSG
VYVDKCLIVPGENTSSYLSLLDNTGEMLVAINDMNISNAITAEYLAQHREFIQRAKVIVADCNISEEALAWILDNAANVP
VFVDPVSAWKCVKVRERLSQIHTLKPNRLEAETLSGIALSGREDVAKVAAWFHQHGLNRLVLSMGGDGVYYSDISGESGW
SAPIKTNVINVTGAGDAMMAGLASCWVDGMPFAESVRFAQGCSSMALSCEYTNNPDLSIANVISLVENAECLN
>SEQF1516_EDU84487.1 transcriptional regulator GalS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITIRDVARQAGVSVATVSRVLNNSTLVSADTREAVMKAVSELDYRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKA
VDLVAQQHQKYVLIGNSYHEAEKERHAIEVLIRQRCNALIVHSKALSDDELAQFMDNIPGMVLINRVVPGYTHRCVCLDN
LSGARMATRMLLNNGHQRIGYLSSSHGIEDDAMRKAGWMSALKEQDIIPPESWIGTGTPDMPGGEAAMVELLGRNLQLTA
VFAYNDNMAAGALTALKDNGIAIPLHLSIIGFDDIPIARYTDPQLTTVRYPIASMAKLATELALQGAAGNIDPRASHCFM
PTLVRRHSVATRQNAAAITNSTNQAM
>SEQF1516_EDU84488.1 LrgA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGMLILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGV
GVMQYFDLLRAQFGPVVVSCAISTLVVFLVVSWSSQLVHGERKVVGQKGSEE
>SEQF1516_EDU84489.1 PAP2 family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKNLPQIVLLNIVGLALFLSWYIPVNHGFWLPIDADIFYFFNQKLVESKAFLWLVALTNNRAFDGCSLLAMGMLMLSFW
LKENAPGRRRIVIIGLVMLLTAVVLNQLGQALIPVKRASPTLTFTDINRVSELLSVPTKDASRDSFPGDHGMMLLIFSAF
MWRYFGKVAGLIALIIFVVFAFPRVMIGAHWFTDIIVGSMTVILIGLPWVLLTPLSDRLITFFDKSLPGKNKHFQNK
>SEQF1516_EDU84490.1 mannitol dehydrogenase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLTDRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYT
VLEKGADGNQAIIVGAVHECLNAKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
APGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHVSFPGTMVDRIVPAATDESLAEI
SQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVAGVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQD
RAFRHAARTLMLDEQAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGRETDWSLLAL
GVAGWMRYVSGVDDAGNAIDVRDPLSDKIRDLVAGSISEQRVTALLSLREVFGDDLPDNPHFVQAIEQARQQIAQFGAHQ
ALLNTLKI
>SEQF1516_EDU84491.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGPCGDNSLVALKLLSPDGDNAWSVMYKLSQALGDIEVPCSVLECEGE
PCLFVNRQDEFAATCRLKNFGVAIAEPFSNYNPF
>SEQF1516_EDU84492.1 NlpC/P60 family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRAVGSETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGV
RYRLGGSTKKGIDCSGFVQRTFREQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHAST
SSGVIISSMNEPYWKKRYNEARRVLSRS
>SEQF1516_EDU84493.1 nucleoside transporter, NupC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVAAALLLQIALGGIMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGS
LVGPKMDVLFDGAGFIFAFRVLPAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFARILSPATELSQVTFENLSFSETP
PKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALINGIIGGIGGWFGFANASLESIFGYVLAPLAWIMGVDWSDANLAG
SLIGQKLAINEFVAYLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGLRALAAATL
SNLMSATIAGFFIGLA
>SEQF1516_EDU84494.1 gentisate 1,2-dioxygenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDNNQNSREQFYQHISGQNLTPLWESLHHLVPKTPNANCAPAYWNYQEIRPLLLESGGLIGAKEAVRRVLVLENPALRG
QSSITATLYAGLQLIMPGEVAPSHRHNQSALRFIVEGKGAFTAVDGERTPMNEGDFILTPQWRWHDHGNPGDEPVIWLDG
LDLPLVNILGCGFAEDYPEEQQPVTRKEGDYLPRYAANMLPLRHQTGNSSPIFNYRYDRSREVLHDLTRLGDADEWDGYK
MRYVNPVTGGYPMPSMGAFLQLLPKGFASRVARTTDSTIYHVVEGSGQVIIGNETFSFSAKDIFVVPTWHGVSFQTTQDS
VLFSFSDRPVQEALGLFREARY
>SEQF1516_EDU84495.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQRLQHAFARKEIGCFTYNPWAIMKVSYNRVFLPEGLPIVCYNRASFFRWIAFLYGFRN
>SEQF1516_EDU84496.1 putative cyclic diguanylate phosphodiesterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIAILVSCLQFLVAWHKHEVKYDTLITDVQKYLDTYFADLKSTTDRLQPLTLDTCKQANPELTARAAFSMNVRTFVLVKD
KKTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSGVFAALNLNLTPSLFYSSRQED
YDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIAGIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVR
MRPGREIMTAIKREQFYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQKMIVPLTQHLFELIARDAAE
LEKVLPVGVKFGINIAPDHLHSESFKANIQKLLTSLPAHHFQIVLEITERDMLKEQEATQLFAWLHSVGVEIAIDDFGTG
HSALIYLERFTLDYLKIDRGFINAIGTETITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPL
PLDDFVRWLKKPYTPQW
>SEQF1516_EDU84497.1 indigoidine synthase A like protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSELKISPELLQISPEVQDALKNKKPVVALESTIISHGMPFPQNAQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEE
IELLGREGHNVTKVSRRDLPFVVAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTV
VCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSPFDVSIRLDSASEIARAMAVKWQSGLNGGLVVANPIPEQ
FAMPEHTINAVIDQAVAEAEAQGVIGKESTPFLLARVAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLAG
>SEQF1516_EDU84498.1 regulatory protein Nsr [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEIHNNDLKQQLMSESAFKDCFLTDVSADTRLFHFLARDYIVQEGQQPSWLFYLTRGRARLYATLANGRVSLIDFFAAP
CFIGEIELIDKDHEPRAVQAIEECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFIL
LSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQFIHDGLLIKSKKGYLIKNRKQLSGLALEMDPENKFSGMMQ
>SEQF1516_EDU84499.1 FAD dependent oxidoreductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKVTRAVIVGGGIGGAATALSLARLGIKVVLLEKAHEIGEIGAGIQLGPNAFSALDSLGVGEVARQRAVFTDHITMMDA
VNAEEVVCIETGQAFRDHFGGPYAVIHRVDIHASVWEAVLTHPDVEYHTSTNVVDIRETEDDVTVFDDRGNSWTGDILIG
CDGVKSVVRQSLLGDAPRVTGHVVYRAVIDRADMPEDLRINAPVLWAGPHCHLVHYPLRGGKQYNLVVTFHSRQQEEWGV
KDGSKEEVLSYFEGIHPRPRQMLDKPTSWRRWSTADREPVAKWGTKRITLVGDSAHPVAQYMAQGACMALEDAVTLGKAL
AQCEGDAAQAFALYESVRIPRTARIVWSTREMGRVYHAAGVERQVRNLLWKGKSQAEFYRGMEWLYGWKEDNCLQPR
>SEQF1516_EDU84500.1 dihydroorotate dehydrogenase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGVVFKTIGFFIANEVSPRFDHLVKEDTGFIGFKNMEQI
AEHPLEENLAALRRLKEDYPDKVLIASIMGENEQQWEELARLVQEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYC
RAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMPIVNGKSSISGYSGKAVKPIALR
FIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGAATLQVTTGIMQYGYRIVEDMASGLSHYLADQGFDSLQEMVGLAN
NNIVPAEDLDRSYIVYPRINLDKCVGCGRCYISCYDGGHQAMEWSEKTRTPHCNTEKCVGCLLCGHVCPVGCIELGEVKF
KKGEKEHPVTL
>SEQF1516_EDU84501.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANWAQKLKLHHLEMLVALGEQGNLTHVARMMNITQPALSKWLSQLEDEIGITLFERHSKGLRPTEGGKLLLQHAQRLIN
DMERSQHELARFKQGGLVGSLKIGCSPVATDCVSQAILHLLTKMPTLHLNIEEKVMTPLLQDLLAGSVDVVVGRIGGRAL
QLPLNYQVLYTEPVCFVARPEHPLAKYATLSWNDLANWRWIVWPTGTPIRISIDNALVDHGVMLPENTIESASMNVSTNL
LQSSDMISILSLRLAQRYASQGQLVILNLPKIEQKGSVGVFWRNNETPSYALSQFLHFLQQN
>SEQF1516_EDU84502.1 S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPPVLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPD
TSPRGEKVANDDGYDLGQGAGFYLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPG
KYTSVSAFAPIVNPCSVPWGIKAFSRYLGEDKNAWLEWDSCALMYASNAQDAIPTLIDQGDNDQFLADQLQPAVLAEAAR
QKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYLLK
>SEQF1516_EDU84503.1 1-phosphofructokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGINVAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIA
NRFQVVQGRTRINVKLTEKDGEVTDFNFSGFEVTPADWERFVTDSLSWLGQFDMVCVSGSLPSGVSPEAFTDWMTRLRSQ
CPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIEAAHALREQGIAHVVISLGAEGALWVNASGEWIA
KPPSVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLRLATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN
>SEQF1516_EDU84504.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDVQQFFVVAVFFLIPIFCFREAWKGWRAGAIDKRVKNAPEPVYVWRAKNPGLFFAYMVAYIGFGILSIGMIVYLIFYR
>SEQF1516_EDU84505.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITPQDAWTWAFLDLIGQVKFLTLFALLFGAGLQMLLPRG
RRWIQSRLTLLVLLGFIHGLLFWDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRA
WTPDASAILYEKYWKLHGGVEAISNRADGVGNSLLALGAQYGWQLAGMMLIGAALMRSGWLKGQFSLRHYRRTGFVLVAI
GVIINLPAIALQWQLDWAYRWCAFLLQMPRELSAPFQAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICT
TLFYHLGLFMQFDRLELLAFVIPVWLANILFSVIWLRYFRQGPVEWLWRQLTLRAAGPAISKTSR
>SEQF1516_EDU84506.1 elongation factor P family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFSDVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGN
EYVFMDKEDYTPYTFTKDQIEEELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLST
GLVIQVPEYLSPGEKIRIHIEERRYMGRAD
>SEQF1516_EDU84507.1 maleylacetoacetate isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLYSFFNSSASYRVRIALALKGINYQTEGVNIRIGQQNELAYRRMNPVGLVPTLLTDEGESLGQSLAIIDWLERHYPQV
PLVPQEEPARNKVLEIVYAIACDIHPLNNLRVLRYLTEELNVSEEEKKRWYAHWIQQGLSAVEQLLRQNQSGQFCVGETP
TLADCCLVPQWANALRMNCDLSGYPRCKAVYDACTQLPAFIAAAPENQQDKISA
>SEQF1516_EDU84508.1 ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRLNPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIANDKPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQD
PWLKQRLENNGWVLWAPIRFGATSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL
AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQA
LGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAIL
LSLLIFIGEAVRDAFDPNKAV
>SEQF1516_EDU84509.1 hypothetical protein ECH7EC4501_2494 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLNAEAHFLKFVLPCPVTLQKTALIVVMTHYLGESDYSLLHTGYNVKTVQS
>SEQF1516_EDU84510.1 protein SanA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPYRQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSG
KVNYLLLSGDNALQSYNEPMTMRKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPEDAQGYPAVTPEQLLELQKKQGK
>SEQF1516_EDU84511.1 ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEFGNAGVLPGAGGEGVRASHAQTGVGNISDSNYRGGRG
LDPEVIAEITHRYGFDKPIHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV
YNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYFDLFPLRGLVSANFDSLPWYQKITDYLWHITLPVLATVIGGF
AALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWKHVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYE
ATVSRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRIDFEGR
>SEQF1516_EDU84512.1 LrgB family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPFLMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQ
LHQIRARWKSIITICFIGSVVAMVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLIAPILFPIILAVMG
>SEQF1516_EDU84513.1 kinase, pfkB family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNREKEILAILRRNPLIQQNEIADMLQISRSRVAAHIMDLMRKGRIKGKGYILTEQEYCVVVGTINMDIRGMADIRYPQ
SASHPGTIHCSAGGVGRNIAHNLALLGRDVHLLSVIGDDFYGEMLLEETRRAGVNVSGCVRLHGQSTSTYLAIANRDDET
VLAINDTHLLEQLSPQLLNGSRDLLRHAGVVLADCNLTAEALEWVFTLAGEIPVFVDTVSEFKAGKIKHWLAHIHTLKPT
LPELEILWGQAITSDADRNAAVNALHQQGVQQLFVYLPDESVYCSEKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFL
EGNNFRDSARFAMACAAISRASGSLNNPTLSADNALSLVPMV
>SEQF1516_EDU84514.1 galactose ABC transporter, periplasmic galactose-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKKVLTLSAVMASMLFGATAHAADTRIGVTIYKYDDNFMSVVRKAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLA
KGVKALAINLVDPAAAGTVIEKARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGDLIAKHWAANQGWDLNK
DGQIQFVLLKGEPGHPDAEARTTYVIKELNDKGIKTEQLQLDTAMWDTAQAKDKMDAWLSGPNANKIEVVIANNDAMAMG
AVEALKAHNKSSIPVFGVDALPEALALVKSGALAGTVLNDANNQAKATFDLAKNLADGKGAADGTNWKIDNKVVRVPYVG
VDKDNLAEFSKK
>SEQF1516_EDU84515.1 endonuclease 4 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPLTTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPV
TEALEKSRDAFIDEMQRCEQLGLSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEH
LAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARTVGFKYLRGMHLNDAKSTFGSRVDRHHSLGEGNIG
HDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLKAQQTEKAVA
>SEQF1516_EDU84516.1 galactose ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQAPTFLSLLNLSNILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAA
VVAATLLQSMDNANKVFPEMATMPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
ISGFDSGFSTFAQGFVALGSFRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPEAAKVSGVNVGLNLLMIYALSGV
FYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGGVSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAI
IIFAVALDSLKYARKK
>SEQF1516_EDU84517.1 lysine-specific permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSETKTTEAPGLRRELKARHLTMIAIGGSIGTGLFVASGATISQAGPGGALLSYMLIGLMVYFLMTSLGELAAYMPVSG
SFATYGQNYVEEGFGFALGWNYWYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFS
LIKVTTVIVFIIVGVLMIIGIFKGAQPAGWSNWTIGEAPFAGGFAAMIGVAMIVGFSFQGTELIGIAAGESEDPGKNIPR
AVRQVFWRILLFYVFAILIISLIIPYTDPSLLRNDVKDISVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYAST
RMLYTLACDGKAPRIFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAISHYRFRRGY
VLQGHDINDLPYRSGFFPLGPIFAFILCLIITLGQNYEAFLKDTIDWGGVAATYIGIPLFLIIWFGYKLIKGTHFVRYSE
MKFPQNDKK
>SEQF1516_EDU84518.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNALSGLQNHTNQYVELIAGRIKRASVASGIWLLSPDAA
>SEQF1516_EDU84519.1 pyridine nucleotide-disulfide oxidoreductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDPGKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTE
KLCQSGCTRAGVDAPIDIGRLQRFVTDFEQQTGMEIYQPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAHPG
GWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEIGKTLTLEQLKAENRAVLVTVGLSSGSGLPLFEHSDVEIAVDFL
LRARQAQGDISIPQSALIIGGGDVAMDVASTLKVLGCQAVTCVAREELDEFPASEKEFASARELGVSIIDGFTPVAVEGN
KVTFKHVRLSGELTMAADKIILAVGQHARLDDFAKLEPQRNTIKTQNYQTRDPQVFAAGDIVEGDKTVVYAVKTGKEAAE
AIHHYLEGACSC
>SEQF1516_EDU84520.1 tRNA-dihydrouridine synthase C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSANTGGANIAPHFFAGDDMRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVKVFHRICPELQNASRTPS
GTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKTVNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVR
LGWDSGEKKFEIADAVQQAGATELVVHGRTKEQGYRAEHIDWQAIGEIRQRLNIPVIANGEIWDWQSAQECMAISGCDSV
MIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQWLSYLRKEYDEATELFQHVRVLNNSP
DIARAIQAIDIGKLR
>SEQF1516_EDU84521.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEI
EQLFREDNGAIRIYASSTIGNYILPAVIARYRHDYPQLPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLE
DELVVFAAPTSPLARGPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGISCLSRR
VIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYCDPANVPR
>SEQF1516_EDU84522.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQAYFSITKFDKIPLFHNIISAFFRADCLHKNSSVCTIMLYQPPYRVTYAKLG
>SEQF1516_EDU84523.1 phosphocarrier protein NPr [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVKQTVEITNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEAEANSVIALLMLDSAKGRQIEVEATGPQEEEALAAVI
ALFNSGFDED
>SEQF1516_EDU84524.1 p-hydroxybenzoic acid efflux pump subunit aaeA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFSADVVAIAPDVSGLITQVNVHNQLVKKGQVLFTIDQP
RYQKALEEAQADVAYYQVLAQEKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAPA
DGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGSNKVLKGTVDSVAAGVTNASSTRD
DKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWPAGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG
>SEQF1516_EDU84525.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTWEYALIGLVVGIIIGAVAMRFGNRKLRQQQALQYELEKNKAELDEYREELVSHFARSAELLDTMAHDYRQLYQHMAKS
SSSLLPELSAEANPFRNRLAESEASNDQAPVQMPRDYSEGASGLLRTGAKRD
>SEQF1516_EDU84526.1 glutamate synthase (NADPH), large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRKPRRHALSVPVRSGSEVGFPQSLGEVHDMLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGAILADG
KTGDGCGLLLQKPDRFFRIVAQERGWRLAKNYAVGMLFLNKDPELAAAARRIVEEELQRETLSIVGWRDVPTNEGVLGEI
ALSSLPRIEQIFVNAPAGWRPRDMERRLFIARRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPADLPRFYLDLADLRLES
AICLFHQRFSTNTVPRWPLAQPFRYLAHNGEINTITGNRQWARARTYKFQTPLIPDLHDAAPFVNEIGSDSSSMDNMLEL
LLAGGMDIIRAMRLLVPPAWQNNPDMDPELRAFFDFNSMHMEPWDGPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLI
TCASEVGIWDYQPDEVVEKGRVGPGELMVIDTRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLPDEEVGSREL
DDDTLASYQKQFNYSAEELDSVIRVLGENGQEAVGSMGDDTPFAVLSSQPRIIYDYFRQQFAQVTNPPIDPLREAHVMSL
ATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFKQLTTMKEEHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTV
LLVLSDRNIAKDRLPVPAPMAVGAIQTRLVDQSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETLGRLVDTH
AIAKDYRTVMLNYRNGINKGLYKIMSKMGISTIASYRCSKLFEAVGLHNDVVGLCFQGAVSRIGGASFEDFQQDLLNLSK
RAWLARKPISQGGLLKYVHGGEYHAYNPDVVRTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVE
PASELFKRFDTAAMSIGALSPEAHEALAEAMNSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGRFGVTPAYLVNADVIQ
IKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHHDIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTI
ATGVAKAYADLITIAGYDGGTGASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAES
FGFGTGPMVALGCKYLRICHLNNCATGVATQDDKLRKNHYHGLPFKVTNYFEFIARETRELMAQLGVTRLVDLIGRTDLL
KELDGFTAKQQKLALSKLLETAEPHPGKALYCTETNPPFDNGLLNAQLLQQAKPFVDERQSKTFWFDIRNTDRSVGASLS
GYIAQTHGDQGLAADPIKAYFNGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSHEASIIGNTC
LYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCILGKTGVNFGAGMTGGFAYVLDESGDFRKRVNP
ELVEVLSVDDLAIHEEHLRGLITEHVQHTGSQRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ
>SEQF1516_EDU84527.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTLADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSP
QLLFLDADRNTLIRRYSDTRRLHPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKREREL
TMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNFIYQTRSYLELWLPMLETNNRSY
LTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRHRTLEKRKP
>SEQF1516_EDU84528.1 ATPase, AFG1 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTPPAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGV
GRGKTWLMDLFYQSLPGERKQRLHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTLTQAHLWLSPLHDETRAQMDKLW
LALAGGKRENSPTLEINHRPLATMGVENQTLAVSFTTLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIAL
VDEFYERHVKLVVSAEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG
>SEQF1516_EDU84529.1 sodium/calcium exchanger protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLATALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEIIVSLAASLHEQRDLAVGTALGSNIIN
ILLILGLAALVRPFTVHSDVLRRELPLMLLVSVVAGSVLYDGQLSRSDGIFLLFLAVLWLLFIVKLARQAERQGTDSLTR
EQLAELPRDGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISELTMGLTAIAIGTSLPELATAIAGVRKGENDIA
VGNIIGANIFNIVIVLGLPALITPGEIDPLAYSRDYSVMLLVSIIFALLCWRRSPQPGRGVGVLLTGGFIVWLAMLYWLS
PILVE
>SEQF1516_EDU84530.1 Mce family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTKKNEIWVGIFLLAALLAALFVCLKAANVTSIRTEPTYTLYATFDNIGGLKARSPVSIGGVVVGRVADITLDPKTYLP
RVTLEIEQRYNHIPDTSSLSIRTSGLLGEQYLALNVGFEDPELGTAILKDGDTIQDTKSAMVLEDLIGQFLYGSKGDDNK
NSGDAPAAAPGNNETTEPVGTTK
>SEQF1516_EDU84531.1 rod shape-determining protein MreC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDTAVSPFYFVSNAPRELLDGVSQTLASRDQLELENRAL
RQELLLKNSELLMLGQYKQENARLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGDVLVTSGLGGRFPEGYPVAVVSS
VKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNGANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQ
PTPQQPTTGNAATAPAAPTQPAANRSLQRATPPQSGAQPPARAPGGQ
>SEQF1516_EDU84532.1 ribonuclease G [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAELLVNVTPSETRVAYIDGGILQEIHIEREARRGIVGNIYKGRVSRVLPGMQAAFVDIGLDKAAFLHASDIMPHTECV
AGEEQKQFTVRDISELVRQGQDLMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESESERERLKKVVAE
YCDEQGGFIIRTAAEGVGEAELASDAAYLKRVWTKVMERKKRPQTRYQLYGELALAQRVLRDFADAELDRIRVDSRLTYE
ALLEFTSEYIPEMTSKLEHYTGRQPIFDLFDVENEIQRALERKVELKSGGYLIIDQTEAMTTVDINTGAFVGHRNLDDTI
FNTNIEATQAIARQLRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTSVNGFSALGLVEMTRKRTRESIEHV
LCNECPTCHGRGTVKTVETVCYEIMREIVRVHHAYDSDRFLVYASPAVAEALKGEESHSLAEVEIFVGKQVKVQIEPLYN
QEQFDVVMM
>SEQF1516_EDU84533.1 protein AaeX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPFSAATDAENNNACSLYTTKVNMSLFPVIVVFGLSFPPIFFELLLSLAIFWLVCRVLVPTGIYDFVWHPALFNTALYCC
LFYLISRLFV
>SEQF1516_EDU84534.1 BolA/YrbA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEDPMENNEIQSVLMNALSLQEVHVSGDGSHFQVIAVGELFDGMSRVKKQQTVYGPLMEYIADNRIHAVSIKAYTPAEW
ARDRKLNGF
>SEQF1516_EDU84535.1 PTS IIA-like nitrogen-regulatory protein PtsN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNNDTTLQLSSVLNRECTRSRVHCQSKKRALEIISELAAKQLSLPPQVVFEAILTREKMGSTGIGNGIAIPHGKLEEDT
LRAVGVFVQLETPIAFDAIDNQPVDLLFALLVPADQTKTHLHTLSLVAKRLADKTICRRLRAAQSDEELYQIITDTKGTP
DEA
>SEQF1516_EDU84536.1 aerobic respiration control sensor protein ArcB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVQKLEEMRERDLSLNVQLKDNIAQLNQEIAVREKAEAELQETFGQLKIEIKEREETQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPADVYSPEAAAKVIETDEKVFRHNVSLTYEQWLDYPDGRKA
CFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTAEQEKY
LKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSALQAQQKGLRFNLEPTLPLPHQVITDGTRLR
QILWNLISNAVKFTQQGQVTVRVRYDEGDMLHFEVEDSGIGIPQDELDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLA
KNMGGDITVTSEQGKGSTFTLTIHAPSVAEEVDDAFDEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKA
ALEMFKPGEYDLVLLDIQLPDMTGLDISRELTKRYPREDLPPLVALTANVLKDKQEYLNAGMDDVLSKPLSVPALTAMIK
KFWDTQDDEESTVTTEENSKSEALLDIPMLEQYLELVGPKLITDGLAVFEKMMPGYVNVLESNLTAQDKKGIVEEGHKIK
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVGEWIEEMKEEWRHDVEVLKAWVAKATKK
>SEQF1516_EDU84537.1 protein TldD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLNLVSEQLLAANGLKHQDLFVILGQLAERRLDYGDLYFQSSYHESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAY
ADQISLLALEQSAQAARTIARDSGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
GVYELILVAATDGTLAADVRPLVRLSVSVLIEEDGKRERGASGGGGRFGYEFFLADLDGEVRADAWAKEAVRMALVNLSA
VAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQY
NVLIENGILKGYMQDKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFGGGQVDITS
GKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNGVGVCGKEGQSLPVGVGQPTLKVDNLTVGGT
A
>SEQF1516_EDU84538.1 ROK family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDALSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNL
GGLLHFPLVKTLGQLTDLPTIAINDAQAAAWAEYQALEGDITDMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLAD
PHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADAKTIFMRAGQGDEQAQQLIHRSAHVLARLIADIKATTDCQCVVVG
GSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHDAGLLGAALLAQGEKL
>SEQF1516_EDU84539.1 stringent starvation protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVTLPGVQVPMEYARDGQIVLNIAPRAVGNLELANDEVRFNARFGGIP
RQVSVPLAAVLAIYARENGAGTMFEPEAAYDEDTSIMNDEEASADNETVMSVIDGDKPDHDDDTHPDDEPPQPPRGGRPA
LRVVK
>SEQF1516_EDU84540.1 arginine repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSS
PLKNLVLDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL
>SEQF1516_EDU84541.1 stringent starvation protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKDNPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLD
ERFPHPPLMPVYPVARGESRLYMHRIEKDWYTLMNTIINGSASEADAARKQLREELLAIAPVFGQKPYFLSDEFSLVDCY
LAPLLWRLPQLGIEFSGPGAKELKGYMTRVFERDSFLASLTEAEREMRLGRS
>SEQF1516_EDU84542.1 toluene ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQSVANLVDMRDVSFTRGNRCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRL
YTVRKRMSMLFQSGALFTDMNVFDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA
LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWILADKKIVAHGSAQALQANPDPRV
RQFLDGIADGPVPFRYPAGDYHADLLPGS
>SEQF1516_EDU84543.1 transcriptional regulator NanR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMIRRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKG
LVQINNGERARVSRPSADTIIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQSLD
NNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVSYQQHIAIVDAIRRHDPDEADRALQS
HLNSVSATWHAFGQTTNKKK
>SEQF1516_EDU84544.1 putative N-acetylmannosamine-6-phosphate 2-epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQAGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDS
PVRITAYIEDVDALAQAGADIIAIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
ETPEEPDLTLVKRLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQWYNTAMKKAVL
>SEQF1516_EDU84545.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRLPGILLLTGAALVVIAALLVSGLRIALPHLDAWRPEILNKIESATGMPVEASQLSASWQNFGPTLEAHDIRAELKDG
GEFSVKRVTLALDVWQSLLHMRWQFRDLTFWQLRFRTNTPITSGGSDDSLEASHISDLFLRQFDHFDLRDSEVSFLTPSG
QRAELAIPQLTWLNDPRRHRAEGLVSLSSLTGQHGVMQVRMDLRDDEGLLSNGRVWLQADDIDLKPWLGKWMQDNIALET
AQFSLEGWMTIDKGDVTGGDVWLKQGGASWLGEKETHTLSVDNLTAHITRENPGWQFSIPDTRITMDGKPWPSGALTLAW
IPEQDVGGKDNKRSDELRIRASNLELAGLEGIRPLAAKLSPALGDVWRSTQPSGKINTLALDIPLQAADKTRFQASWSDL
AWKQWKLLPGAEHFSGTLSGSVENGLLTASMKQAKMPYETVFRAPLEIADGQATISWLNNDKGFQLDGRNIDVKAKAVHA
RGGFRYLQPANDEPWLGILAGISTDDGSQAWRYFPENLMGKDLVDYLSGAIQGGEADNATLVYGGNPQLFPYKHNEGQFE
VLVPLRNAKFAFQPDWPALTNLGIELDFINDGLWMKTDGVNLGGVRASNLTAVIPDYSKEKLLIDADIKGPGKAVGPYFD
ETPLKDSLGATLQELQLDGDVNARLHLDIPLNGELVTAKGEVTLRNNSLFIKPLDSTLKNLSGKFSFINGDLQSEPLTAS
WFNQPLNVDFSTKEGAKAYQVAVNLNGNWQPAKTGVLPAAVNEALSGSVAWDGKVGIVLPYHAGATYNVELNGDLKNVSS
HLPSPLAKPAGEPLPVNVKVDGNLNSFELTGQAGADNHFNSRWLLGQKLTLDRAIWAADSKTLPPLPEQSGVELNMPPMN
GAEWLALFQKGAAESVGGAASFPQHITLRTPMLSLGNQQWNNLSIVSQPTANGTQVEAQGREINATLAMRNNAPWLANIK
YLYYNPSVAKTRGDSTPSSPFPTTERINFRGWSDAQIRCAECWFWGQKFGRIDSDITISGNTLTLTNGLIDTGFSRLTAD
GEWINNPGNERTSLKGKLRGQKIDAAAEFFGVTTPIRQSSFNVDYDLHWRKAPWQPDEATLNGIIHTQLGKGEITEINTG
HAGQLLRLLSVDALMRKLRFDFRDTFGEGFYFDSIRSTAWIKDGVMHTDDTLVDGLEADIAMKGSVNLVRRDLNMEAVVA
PEISATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYHISGPLDDPQINEVLRQPRKEKAQ
>SEQF1516_EDU84546.1 ribosomal protein L13 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEYTPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGH
IGGIKQATFEEMIARRPERVIEIAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI
>SEQF1516_EDU84547.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIYTFDFDEIESQEDFYRDFSQTFGLAKDKVRDLDSLWDVLMNDVLPLPLEIEFVHLGEKTRRRFGALILLFDEAEEEL
EGHLRFNVRH
>SEQF1516_EDU84548.1 MFS transporter, sialate:H+ symporter (SHS) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLTEVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGD
RYGRRLAMVTSIVLFSAGTLACGFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVA
AQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILYRGEHRIANIVMTLAAATALWFC
FAGNLQNAAIVAVLGLLCTAIFISFMVQSTGKRWPTGVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYNPHTVANVLFFS
GFGAAVGCCVGGFLGDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIGGYFDTDQR
AAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLIGLDMPSRVQRWLRPEALRTHDAIDGKPFSG
AVPFGSAKNDLVKTKS
>SEQF1516_EDU84549.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRLSEQSPLGTGRHRKCYAHPEDAQRCIKIVYHRGDGGDKEIRRELKYYAHLGRRLKDWSGIPRYHGTVETDCGTGYVY
DVIADFDGKPSITLTEFAEQCRYEEDVAQLRQLLKQLKRYLQDNRIVTMSLKPQNILCHRISESEVIPVVCDNIGESTLI
PLATWSKWCCLRKQERLWKRFIAQPALAIALQKDLQPRESKTLALASREA
>SEQF1516_EDU84550.1 toluene ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLNALASLGHKGIKTLRTFGRAGLMLFNALVGKPEFRKHAPLLVRQLYNVGVLSMLIIVVSGVFIGMVLGLQGYLVLTT
YSAETSLGMLVALSLLRELGPVVAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTV
IFVAVGIWGGSLVGVSWKGIDSGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWISLFNGYDAIPTSAGISRATTRTVV
HSSLAVLGLDFVLTALMFGN
>SEQF1516_EDU84551.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKSEHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQ
PVLTTFDKDKIPTWSVKADKAKLTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSG
LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP
>SEQF1516_EDU84552.1 toluene tolerance protein Ttg2D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKRLMMVALLVIAPLSAATAADQTNPYKLMDEAAQKTFDRLKNEQPQIRANPDYLRTIVDQELLPYVQVKYAGALVLGQ
YYKSATPAQRDAYFAAFREYLKQAYGQALAMYHGQTYQIAPEQPLGDKTIVPIRVTIIDPNGRPPVRLDFQWRKNSQTGN
WQAYDMIAEGVSMITTKQNEWGTLLRTKGIDGLTAQLKSISQQKITLEEKK
>SEQF1516_EDU84553.1 RNA polymerase sigma-54 factor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALESNPLLEQIDTHEEIDTRETQDSETLDTADALEQKEMPE
ELPLDASWDTIYTAGTPSGTSGDYIDDELPVYQGETTQTLQDYLMWQVELTPFSDTDRAIATSIVDAVDDTGYLTVPLED
ILESMGDEEIDIDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKTTPWLEEARLIISDHLDLLANHDFRTLMRVTR
LKEDVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDVLVRKHNGHWTVELNSDSIPRLQINQHYASMCNNARNDGDSQFIR
SNLQDAKWLIKSLESRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHSPRGIFELK
YFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQGIMVARRTVAKYRESLSIPPSNQRKQLV
>SEQF1516_EDU84554.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMMGEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDNIFMNVMTFNTQSPVEKKAELHEQYIDIQLLLKGEER
ILFGTAGTARQCEEFHHEDDYQLCSAIENEQTINLKPGMFAVFMPGEPHKPGCVVGEPGEIKKVVVKVKADLMA
>SEQF1516_EDU84555.1 YrbB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSESLSWMQTGDTLALSGELDQDVLLPLWEMREEAVKGITCIDLSRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDK
VYTLAKLYNLPADVLPR
>SEQF1516_EDU84556.1 periplasmic serine peptidase DegS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFVKLLRSVAIGLIVGAILLVAMPSLRSLNPLSTPQFDSTDETPASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLG
SGVIMDQRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGN
PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQL
ATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMD
QVAEIRPGSVIPVVVMRDDKQLTLQVTIQEYPATN
>SEQF1516_EDU84557.1 enhancing lycopene biosynthesis protein 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIGVILSGCGVYDGSEIHEAVLTLLAISRSGAQAVCFAPDKQQVDVINHLTGEAMTETRNVLIEAARITRGEIRPLAQ
ADAAELDALIVPGGFGAAKNLSNFASLGRECTVDRELKALAQAMHQAGKPLGFMCIAPAMLPKIFDFPLRLTIGTDIDTA
EVLEEMGAEHVPCPVDDIVVDEDNKIVTTPAYMLAQNIAEAASGIDKLVSRVLVLAE
>SEQF1516_EDU84558.1 transcriptional activator AaeR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDELQVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVH
EQLYAFNNTPIGTLRIGCSSTMAQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRFVTNDPMTLVRWLTAGAGIAYVP
LMWVINEINRGELEILLPRYQSDPRPVYALYTEKDKLPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK
>SEQF1516_EDU84559.1 ribosomal protein S9 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETARMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIR
HGITRALMEYDESLRSELRKAGFVTRDARQVERKKVGLRKARRRPQFSKR
>SEQF1516_EDU84560.1 lipopolysaccharide ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGI
GYLPQEASIFRRLSVYDNLMAVLQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFIL
LDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHGTPTEILQDEHVKRVYLGEDFR
L
>SEQF1516_EDU84561.1 rod shape-determining protein MreD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILLYWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLA
MSIIAYLVALKYQLFRNLALWQQALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
VQ
>SEQF1516_EDU84562.1 3-deoxy-manno-octulosonate-8-phosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKAGASLATCYGPVSADVIAKAENIRLLILDVDGVLSDGLIYMGNNGEELKAFNVRDGYGIRCALTSDIEVAIITGRKA
KLVEDRCATLGITHLYQGQSNKLIAFSDLLEKLAIAPENVAYVGDDLIDWPVMEKVGLSVAVADAHPLLIPRADYVTRIA
GGRGAVREVCDLLLLAQGKLDEAKGQSI
>SEQF1516_EDU84563.1 arabinose 5-phosphate isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHVELQPGFDFQQAGKEVLAIERECLAELDQYINQNFTLACEKMFWCKGKVVVMGMGKSGHIGRKMAATFASTGTPSFF
VHPGEAAHGDLGMVTPQDVVIAISNSGESSEITALIPVLKRLHIPLICITGRPESSMARAADVHLCVKVAKEACPLGLAP
TSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVNDIMHTGDEIPHVKKTASLRDALLEVTRKNLGMT
VICDDNMMIEGIFTDGDLRRVFDMGVDVRQLSIADVMTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMH
DLLRAGVV
>SEQF1516_EDU84564.1 lipopolysaccharide ABC transporter, periplasmic lipopolysaccharide-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFKTNKLSLNLVLASSLLAASIPAFAVTGDTDQPIHIESDQQSLDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGE
QGKEVIDGYGKPATFYQMQDNGKPVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
TTVLVPSQLQDKNNKGQTPAQKKGN
>SEQF1516_EDU84565.1 septum formation protein Maf [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQYVVRLAREKARAGVAQTAKDLPVLGADTIVILNGEVL
EKPRDAEHAAQMLRKLSGQTHQVMTAVALADSRHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFV
RKINGSYQAVVGLPLVETYELLSNFNALREKRDKHDG
>SEQF1516_EDU84566.1 malate dehydrogenase, NAD-dependent [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVA
RKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAE
LKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQAAARFGLSLVR
ALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVEERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK
>SEQF1516_EDU84567.1 p-hydroxybenzoic acid efflux pump subunit aaeB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAAIVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIA
GLVIIIAMIRAPLLMILVCCIWAGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCA
IMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQGMRSNLNMESSRWARANRRLKA
INTLSLTLITQSCETYLIQNTRPELITDTFREFFDTPVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLL
KRGVISNTKINATEEEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTSLAMRLPNP
RMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIEVQKRRLGSMGALASTINIIVLDNPMTFHFS
QFLDSALGQIVGCVLAFTVILLVRDKSRDRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKF
RLALTMIIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEKLCIWQAPPQVTEPVHR
LAGMLHKYQHALTDS
>SEQF1516_EDU84568.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESLSERTSTGYQQIHDGIIHLVDSARTETVRSVNALMTATYWEIGRRIVEFEQGGEARAAYGAQLIKRLSKDLSLRYKR
GFSAKNLRQMRLFYLFFQHVEIRQTVSGELTPLPWSTYVRLLSVKNADTRSFYEKETLRCGWSVRQLERQIATQFYERTL
LSHDKSAMLQQHAPAETHILPQQAIRDPFVLEFLELKDEYSESDFEEALINHLMDFMLELGDDFAFVGRQRRLRIDDNWF
RVDLLFFHRRLRCLLIVDLKVGKFSYSDAGQMNMYLNYAKEHWTLPDENPPIGLVLCAEKGVGEAHYALAGLPNTVLASE
YKMQLPDEKRLADELVRTQAVLEEGYRLR
>SEQF1516_EDU84569.1 ribosomal subunit interface protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLNITGNNVEITEALREFVTAKFAKLEQYFDRINQVYVVLKVEKVTHTSDATLHVNGGEIHASAEGQDMYAAIDGLIDK
LARQLTKHKDKLKQH
>SEQF1516_EDU84570.1 protein YcfR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKTTVAALSVLSVLSFGAFAADSIDAAQAQNREAIGTVSVSGVASSPMDMREMLNKKAEEKGATAYQITEARSGDTWH
ATAELYK
>SEQF1516_EDU84571.1 glutamate synthase (NADPH), small subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQNVYQFIDLQRVDPPKKPLKIRKIEFVEIYEPFSEGQAKAQADRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEA
AELSHQTNTLPEVCGRVCPQDRLCEGSCTLNDEFGAVTIGNIERYINDKAFEMGWRPDMSGVKQTGKKVAIIGAGPAGLA
CADVLTRNGVQAVVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTEVGRDVQLDDLLSDYDAVFLGVG
TYQSMRGGLENEDADGVYAALPFLIANTKQLMGFGETREEPFVSMEGKRVVVLGGGDTAMDCVRTSVRQGAKHVTCAYRR
DEENMPGSRREVKNAREEGVEFKFNVQPLGIEVNGNGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHIVPADAVIMAFG
FRPHSMEWLAKHSVELDSQGRIIAPEGSDNAFQTSNPKIFAGGDIVRGSDLVVTAIAEGRKAADGIMNWLEV
>SEQF1516_EDU84572.1 monofunctional biosynthetic peptidoglycan transglycosylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAVMVERQVSAWLHGNFRYVAHSDRVSMDQISPWMGLAV
IAAEDQTFPEHWGFDVASIEKALAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSAPSGYVRSRQAWILRQMYQLGGEPFMQQHQ
LD
>SEQF1516_EDU84573.1 serine peptidase DegQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDL
PDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
KLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV
GIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKTGDIITSLNGK
PLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKG
SPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESIYLLMR
>SEQF1516_EDU84574.1 radical SAM protein, TIGR01212 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGGCTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRY
LAYFQAYTSTFAEVQVLRSMYQQAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
HDFACYQRTTQLARQRGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHIVKGSIMAKAWEAGRLNGIELED
YTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWCENRWTGMVELDRYLNEHGVQGSALGRPWLPPTE
>SEQF1516_EDU84575.1 N-acetylneuraminate lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYVGGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHV
GCVSTAESQQLAASAKRYGFDAVSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPG
VGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQGIVKALKEGDIQTAQKLQTECN
KVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGPVDEKYLPELKALAQQLMQERG
>SEQF1516_EDU84576.1 tripeptide permease TppB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIMAVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWL
GDKVLGTKRVIMLGAIVLAIGYALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVN
IGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINYRNLLLTIIGVVALIAIATWLLH
NQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMIVAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHTILGLAVEPEQ
YQALNPFWIIIGSPILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQSIGELMIS
GLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDPLMSLEVYGRVFLQIGVATAVIAVLMLLTAP
KLHRMTQDDAADKAAKAAVA
>SEQF1516_EDU84577.1 arginine/ornithine antiporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWGITGAGILLLAFAMLILTRIRPELDGGIFTYAREGFG
ELIGFCSAWGYWLCAVIANVSYLVIVFSALSFFTDTPELRLFGDGNTWQSIVGASALLWIVHFLILRGVQTAASINLVAT
LAKLLPLGLFVVLAMMMFKLDIFKLDFTGLALGVPVWEQVKNTMLITLWVFIGVEGAVVVSARARNKRDVGKATLLAVLS
ALGVYLLVTLLSLGVVARPELAEIRNPSMAGLMVEMMGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAATHKAFPRI
FARQNAQAAPSASLWLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHKAVGVGACIYGLWL
LYASGPMHLLLSVVLYAPGLLVFLYARKTHTHDNVLNRQEMVLIGMLLIASVPATWMLVG
>SEQF1516_EDU84578.1 electron transport complex, RnfABCDGE type, A subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLATTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILV
IAVVVQFTEMVVRKTSPVLYRLLGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAV
ADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL
>SEQF1516_EDU84579.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLSTCYAALLLALASPAVLAAPGSCERIQSDISQRIINNGVPESSFTLSIVPNDQVDQPDSQVVGHCANDTHKILYTRT
TSGNVSAPAQSTQDGAPAEPQ
>SEQF1516_EDU84580.1 acid shock protein repeat [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKQIEGMTMKKVLALVVAAAMGLSSAAFAAETATTPAPTATTTKAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQ
KAPEQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAKKHSHQQPAKPAAQPAA
>SEQF1516_EDU84581.1 mannose-6-phosphate isomerase, class I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKLINSVQNYAWGSKTALTELYGMENPSSQPMAELWMGAHPKSSSRVQNAAGDIVSLRDVIESDKSTLLGEAVAKRFGE
LPFLFKVLCAAQPLSIQVHPNKHKSEIGFAKENAAGIPMDAAERNYKDPNHKPELVFALTPFLAMNAFREFSEIVSLLQP
VAGAHPAIAHFLQQPDAERLSELFASLLNMQGEEKSRALAILKSALDSQQGEPWQTIRLISEFYPDDSGLFSPLLLNVVK
LNPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAGLTPKYIDIPELVANVKFEAKPANQLLTQPVKQGAELDFPIPVDD
FAFSLHDLSDKETTISQQSAAILFCVEGDATLWKGSQQLQLKPGESAFIAANESPVTVKGHGRLARVYNKL
>SEQF1516_EDU84582.1 electron transport complex, RnfABCDGE type, E subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLATTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVV
SAVQMLINAYAFGLYQSLGIFIPLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDG
ADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDERMKKRRTEAAAERALPNGETGNV
>SEQF1516_EDU84583.1 putative permease, PerM family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKPLITLNGLKIVIMLGMLVIILCGIRFAAEIIVPFILALFIAVILNPLVQHMVRWRVPRVLAVSILMTIIVMAMVLLL
AYLGSTLNELTRTLPQYRNSIMTPLQALEPLLQRVGIDVSVDQLAHYIDPNAAMTLLTNLLTQLSNAMSSIFLLLLTVLF
MLLEVPQLPGKFKQMMARPVEGMAAIQRAIDSVSHYLVLKTAISIITGLVAWAMLAALDVRFAFVWGLLAFALNYIPNIG
SVLAAIPPIAQVLVFNGFYEALLVLAGYLLINLVFGNILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTII
VKIALEQTAGGQSIAVLLSDLNKE
>SEQF1516_EDU84584.1 major facilitator family transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRTTTVDGAPASDTDKQSISQPNQFIKRGTPQFMRVTLALFSAGLATFALLYCVQPILPVLSQEFGLTPANSSISLSIS
TAMLAIGLLFTGPLSDAIGRKPVMVTALLLASICTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAF
SMGLYISGNSIGGMSGRLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHFRPTSLRPKSLFINFRLHWRDRGL
PLLFAEGFLLMGSFVTLFNYIGYRLMLSPWHVSQAVVGLLSLAYLTGTWSSPKAGTMTTRYGRGPVMLFSTGVMLFGLLM
TLFSSLWLIFAGMLLFSAGFFAAHSVASSWIGPRAKRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNGVGAFIALM
LVIALLVGTRLHRRLHA
>SEQF1516_EDU84585.1 hypothetical protein ECH7EC4501_0396 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNRSLGMPIRMIFPSIGFIDDGLPVSGATQAAHVRAKCYSVKIN
>SEQF1516_EDU84586.1 peptidase, S1A (chymotrypsin) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTTIAVVLGAISLTSAFVFADKPDVAKSANDEVSTLFFGHDDRVPVNDTTQSPWDAVGQLETASGNLCTATLIAPNLAL
TAGHCLLTPPKGKADKAVALRFVSNKGLWRYDIHDIEGRVDPTLGKRLKADGDGWIVPPAAAPWDFGLIVLRNPPSGITP
LPLFEGDKAALTAALKAAGRKVTQAGYPEDHLDTLYSHQNCEVTGWAQTSVMSHQCDTLPGDSGSPLMLHTDDGWQLIGV
QSSAPAAKDRWRADNRAISVTGFRDKLDQLSQK
>SEQF1516_EDU84587.1 DNA replication terminus site-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNIMARYDLVDRLNTTFRQMEQELAAFAAHLEQHKLLVARVFSLPEVKKEDEHNPLNRIEVKQHLGNDAQSQALRHFRH
LFIQQQSENRSSKAAVRLPGVLCYQVDNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAY
RTLTVLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQDIAALPQNAKLKIKRPVKV
QPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGELLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD
>SEQF1516_EDU84588.1 dimethylsulfoxide reductase, B subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTQYGFFIDSSRCTGCKTCELACKDFKDLGPEVSFRRIYEYAGGDWQEDNGVWHQNVFAYYLSISCNHCDDPACTKVCP
SGAMHKREDGFVVVDEDVCIGCRYCHMACPYGAPQYNAEKGHMTKCDGCYSRVAEGKQPICVESCPLRALEFGPIEELRQ
KHGTLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPEEV
>SEQF1516_EDU84589.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKSLVAVGVIVALGVVWTGGAWYTGKKIETHLEDMVAQANAQLKLTAPESNLEVSYQNYHRGVFSSQLQLLVKPIAGKE
NPWIKSGQSVIFNESVDHGPFPLAQLKKLNLIPSMASIQTTLVNNEVSKPLFDMAKGETPFEINSRIGYSGDSSSDISLK
PLNYEQKDEKVAFSGGEFQLNADRDGKAISLSGEAQSGRIDAVNEYNQKVQLTFNNLKTDGSSTLASFGERVGNQKLSLE
KMTISVEGKELALLEGMEISGKSDLVNDGKTINSQLDYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYNAQTQA
LLAQPEIANNPELYQEKVTEAFFSALPLMLKGDPVITIAPLSWKNSQGESALNLSLFLKDPATTKEAPQTLAQEVDRSVK
SLDAKLTIPVDMATELMTQVAKLEGYQEDQAKKLAKQQVEGASAMGQMFRLTTLQDNTITTSLQYTNGQITLNGQKMPLE
DFVGMFAMPALNVPVVPAIPQQ
>SEQF1516_EDU84590.1 maltose regulon modulator MalY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDFSKVVDRHGTWCTQWDYVADRFGTADLLPFTISDMDFATAPCIIEALNQRLMHGVFGYSRWKNDEFLAAIAHWFSTQ
HYTAIDPQSVVYGPSVIYMVSELIRQWSETGEGVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADGWFCDMGKLEAVLAK
PECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWSNVARGDWALLTSGSKSFNIPAL
TGAYGIIENSSSRDAYLSALKGRDGLSSPSVLALTAHIAAYQQGAPWLDALRVYLKDNLTYIADKMNAAFPELNWQIPQS
TYLAWLDLRPLNIDDNALQKALIEQEKVAIMPGYTYGEEGRGFVRLNAGCPRSKLEKGVAGLINAIRAVR
>SEQF1516_EDU84591.1 haemolysin expression modulating protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAADHRRAELVSGGRLFDLGQVPKSVWHYVQ
>SEQF1516_EDU84592.1 maltose regulon regulatory protein MalI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATAKKITIHDVALAAGVSVSTVSLVLSGKGRISTATGERVNAAIEELGFVRNRQASALRGGQSGVIGLIVRDLSAPFYA
ELTAGLTEALEAQGRMVFLLHGGKDGEQLAQRFSLLLNQGVDGVVIAGAAGSSDDLRRMAEEKAIPVIFASRASYLDDVD
TVRPDNMQAAQLLTEHLIRNGHQRIAWLGGQSSSLTRAERVGGYCATLLKFGLPFHSDWVLECTSSQKQAAEAITALLRH
NPTISAVVCYNETIAMGAWFGLLKAGRQSGESGVDRYFEQQVSLAAFTDATPTTLDDIPVTWASTPARELGTTLADRMMQ
KITHEETHSRNLIIPARLIAAK
>SEQF1516_EDU84593.1 hypothetical protein ECH7EC4501_0409 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDGDDYARFGNNTLQCHVFCLLKHALLLQLASFAAK
>SEQF1516_EDU84594.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKITLSKRIDLLAFLLPCALALSTTVHAETNKLVIESGDSAQSRQHAAMEKEQWNDTGNLRQKVNKRTEKEWDKADAAFD
NRDKCEQSANINAYWEPNTLRCLDRRTGRVITP
>SEQF1516_EDU84595.1 anaerobic dimethyl sulfoxide reductase, C subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKTDADRQHIVRGMFFLWLLMGIGFIASVMHLGSPLRAFNSLNRIGA
SGLSNEIAAGSIFFAVGGLWWLVAVIGKMPQALGKLWLLVSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFVTVLLS
GPILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLSSIHSSVQQASALVPDYASLQVWRVVLLCAGLGCWLC
PLIRRREPHVAGLILGLILILGGEMIGRVLFYGLHMTVGMAIAG
>SEQF1516_EDU84596.1 NAD(P) transhydrogenase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIALIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEM
TEMPELVAILHSFVGLAAVLVGFNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR
HKMNLAALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLSNDL
LIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVA
QAQYPVAEITEKLRARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGANDTVNPAAQD
DPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGDAKASVDAILKAL
>SEQF1516_EDU84597.1 PTS system, maltose and glucose-specific IIBC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSSHDVITLLPVLGNPVLQAIFTWMSKIGSFAFSFLPVM
FCIAIPLGLARENKGVAAFAGFVGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWM
LHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINSAGDFGPMLFGTGERLLLPFGLH
HILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSCPTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHK
IKGLLISGLIACVVGGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHGLSTKWYMV
PVVVAIWFVVYYVIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGYNVPAILEALGGADNIVSLDNCITRLRLSVK
DMSLVNVQALKDNRAIGVVQLNQHNLQVVIGPQVQSVKDEMAGLMHTVQA
>SEQF1516_EDU84598.1 electron transport complex, RnfABCDGE type, B subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEILPQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEA
VMLKIAELLNVEPQPLDGEAQELTPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTH
CISLQPVAETPDSWKWDLNTIPVRIIPVEHHA
>SEQF1516_EDU84599.1 oxidoreductase, NAD-binding [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDNIRVGLIGYGYASKTFHAPLIAGTPGLELAVISSSDETKVKADWPTVTVVSEPKHLFNDPNIDLIVIPTPNDTHFPL
AKAALEAGKHVVVDKPFTVTLSQARELDALAKSLGRVLSVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVR
DRWREQGGPGSGIWYDLAPHLLDQAITLFGLPVSMTVDLAQLRPGAQSTDYFHAILSYPQRRVILHGTMLAAAESARYIV
HGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRDGVLTRVEGEERVEETLLTVPGNYPAYYAAIRDALNGDGENPVPA
SQAIQVMELIELGIESAKHRATLCLA
>SEQF1516_EDU84600.1 electron transport complex, RnfABCDGE type, G subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKALFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYI
AKQDDKPVAAVLEATAPDGYSGAIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAV
KKDGGNFDQFTGATITPRAVVNAVKRAGLYAQTLPEQLSQLPACGE
>SEQF1516_EDU84601.1 transcriptional regulator UidR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAISPGTLYHHFISKEALIQAIILQDQERALARFREPIEG
IHFVDYMVESIVSLTHEAFGQRALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTSRLLL
DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS
>SEQF1516_EDU84602.1 oxidoreductase, short chain dehydrogenase/reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKTQPLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAIDGLINAGAQCIQADFSTNDGVMAFADEVLKSTHGLR
AILHNASAWMAEKPGAPLADVLACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALD
NMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVDYLLTSCFVTGRSFPLDGGRHLR
>SEQF1516_EDU84603.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNLNAVFQFGVDNGYLADNPFKGISPLKESRTIPDPLSREEFIRLIDACRNQQAKNLWCNTVLSGDF
>SEQF1516_EDU84604.1 chloride transporter, chloride channel (ClC) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRRLLIATVVGILAAFAVAGFRHAMLLLEWLFLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPH
APTDYMEALQTDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWIACGAAAGMAAAY
RAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDALLYSVQLSVTVQARDYALIISTGVLAGLCGPLLLT
LMNACHRGFVSLKLAPPWQLALGGLIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGG
VFTPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEMTGEYQLLPGLLIACVIASVI
SRTLHRDSIYRQHTAQHS
>SEQF1516_EDU84605.1 glucuronide permease uidB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQQLSWRTIVGYSLGDIANNFAFAMGALFLLSYYTDVAGVGAAAAGTMLLLVRVFDAFADVFAGRVVDSVNTRWGKFRP
FLLFGTAPLMIFSVLVFWVPTDWSHGSKVVYAYLTYMGLGLCYSLVNIPYGSLATAMTQQPQSRARLGAARGIAASLTFV
CLAFLIGPSIKNSSPEEMVSVYHFWTIVLAIAGMVLYFICFKSTRENVVRIVAQPSLKISLQTLKRNRPLFMLCIGALCV
LISTFAVSASSLFYVRYVLNDTGLFTVLVLVQNLVGTVASAPLVPGMVARIGKKNTFLIGALLGTCGYLLFFWVSVWSLP
VALVALAIASIGQGVTMTVMWALEADTVEYGEYLTGVRIEGLTYSLFSFTRKCGQAIGGSIPAFILGLSGYIANQVQTPE
VIMGIRTSIALVPCGFMLLAFVIIWFYPLTDKKFKEIVVEIDNRKKVQQQLISDITN
>SEQF1516_EDU84606.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQVNCFFNSEIFYSLVIKITMLWQCKNIARIRLKSFKFTHATNIDLQNITLAIFKKLDYLTRKNAK
>SEQF1516_EDU84607.1 YdgH protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLKNTLLASALLSATAFSVNAATELTPEQAAAVKPFDRVVVTGRFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGNSG
NWRVVADLYKADAEKAEETSNRVINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQIDA
NQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEAAKKVEIPGVATTASPSSEVGRFFETQSSKGGRYTV
TLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTEVSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK
>SEQF1516_EDU84608.1 anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKIHTTEALMKAEISRRSLMKTSALGSLALASSAFTLPFSQMVRAAEAPVEEKAVWSSCTVNCGSRCLLRLHVKDDTVY
WVESDTTGDDVYGNHQVRACLRGRSIRRRMNHPDRLKYPMKRVGKRGEGKFERISWDEALDTISDNLRRILKDYGNEAVH
VLYGTGVDGGNITNSNVPYRLMNSCGGFLSRYGSYSTAQISAAMSYMFGANDGNSPDDIANTKLVVMFGNNPAETRMSGG
GVTYYVEQARERSNARMIVIDPRYNDTAAGREDEWLPIRPGTDGALACAIAWVLISENMVDQPFLDKYCVGYDEKTLPAN
APRNAHYKAYILGEGPDGIAKTPEWAAKITSIPAEKIIQLAREIGSAKPAYICQGWGPQRHSNGEQTSRAIAMLSVLTGN
VGINGGNSGVREGSWDLGVEWFPMLENPVKTQISVFTWTDAIDHGTEMTATRDGVRGKEKLDVPIKFLWCYASNTLINQH
GDINHTNEVLQDDSKCEMIVGIDHFMTASAKYCDILLPDLMPTEQEDLISHESAGNMGYVILAQPATSAKFERKPIYWML
SEVAKRLGPDVYQTFTEGRSQHEWIKYLHAKTKERNPEMPDYEEMKTTGIFKKKCPEEHYVAFRAFREDPQANPLKTPSG
KIEIYSERLAKIADTWELKKDEIIHPLPAYTPGFDGWDDPLRKTYPLQLTGFHYKARTHSSYGNIDVLQQACPQEVWINP
IDAQARGIRHGDTVRVFNNNGEMLIAAKVTPRILPGVTAIGQGAWLKADMFGDRVDHGGSINILTSHRPSPLAKGNPSHS
NLVQIEKV
>SEQF1516_EDU84609.1 sensor histidine kinase RstB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLFIQFYLLLFVCFLVMSLLVGLVYKFTAERAGKQSLDDLMNSSLYLMRSELREIPPHDWGKTLKEMDLNLSFDLRVE
PLSKYHLDDISMHRLRGGEIVALDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALIAFIAISLAFPVFIWMRPH
WQDMLKLEAAAQRFGDGHLNERIHFDEGSSFERLGIAFNQMADNINALIASKKQLIDGIAHELRTPLVRLRYRLEMSDNL
SAAESQALNRDISQLEALIEELLTYARLDRPQNELHLSEPDLPLWLSTHLADIQAVTPDKTVRIKTLMQGHYAALDMRLM
ERVLDNLLNNALRYCHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLAIVHSIALA
MGGTVNCDTSELGGARFSFSWPLWHNIPQFTSA
>SEQF1516_EDU84610.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIELRHLRYFVAVAEELHFGRAAARLNISQPPLSQQIQALEQQIGARLLARTNRSVLLTAAGKQFLADSRQILSMVDDA
AARAERLHQGEAGELRIGFTSSAPFIRAVSDTLSLFRRDYPDVHLQTREMNTREQIAPLIEGTLDMGLLRNTALPETLEH
AVIVHEPLMAMIPHDHPLANNPNVTLAELAKEPFVFFDPHVGTGLYDDILGLMRRYHLTPVITQEVGEAMTIIGLVSAGL
GVSILPASFKRVQLNEMRWVPIAEEDAVSEMWLVWPKHHEQSPAARNFRIHLLNALR
>SEQF1516_EDU84611.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTTTPQRIGGWLLGPLAWLLVALLSTTLALLLYTAALSSPQTFQTLGAQALTTQILWGVSFITAIAMWYYTLWLTIAFF
KRRRCVPKHYIIWLLISVLLAVKAFAFSPVEDGIAVRQLLFTLLATALIVPYFKRSSRVKATFVNP
>SEQF1516_EDU84612.1 adenosine deaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLIPHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVA
FENIEDAARNGLHYVELRFSPGYMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAERIGHGVKAIEDRALMDFLAEQQI
GIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASINTDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLNA
EEKRALREKVAAK
>SEQF1516_EDU84613.1 endonuclease III [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATDVSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIG
LYNSKAENIIKTCRILLEQHNSEVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE
EKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI
>SEQF1516_EDU84614.1 fumarate hydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNKPFHYQAPFPLKKDDTEYYLLTSEHVSLSEFEGQEILKVAPEALTLLARQAFHDASFMLRPAHQQQVADILRDPEAS
ENDKYVALQFLRNSDIAAKGVLPTCQDTGTAIIVGKKGQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNT
GTNLPAQIDLYAVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRTLGTAACPPYHIAFVIGGTSAET
NLKTVKLASAKYYDELPTEGNEHGQAFRDVELEKELLIEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSA
DRNIKAKINRQGIWIEKLEHNPGKYIPEELRKAGEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVGRDIAHAKL
KERMDNGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQLQALGGSMIMLAKGNRSQQVTDACKKHGGF
YLGSIGGPAAVLAQGSIKSLECVEYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQQIQLTQCTRCVK
>SEQF1516_EDU84615.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGLVIKAALGALVVLLIGVLAKTKNYYIAGLIPLFPTFALIAHYIVASERGIEALRATIIFSMWSIIPYFVYLVSLWYFT
GMMRLPAAFVGSVACWGISAWVLIICWIKLH
>SEQF1516_EDU84616.1 oxidoreductase, short chain dehydrogenase/reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQLGGQAFACRCDITSEQELSALAD
FAISKLGKVDILVNNAGGGGPKPFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYA
SSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRLGQPQDIANAALFLCSPAASWVS
GQILTVSGGGVQELN
>SEQF1516_EDU84617.1 diamine N-acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPSAHSVKLRPLEREDLRYVHQLDNNASVMRYWFEEPYEAFVELSDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHV
HRRAEFQIIISPEYQGKGLATRAAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFSVEGELMHEFFINGQYRNAI
RMCIFQHQYLAEHKTPGQTLLKPTAQ
>SEQF1516_EDU84618.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLALFVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDG
VKLTLYDWTGPLIALCGMLIIVVGWGRT
>SEQF1516_EDU84619.1 electron transport complex, RnfABCDGE type, D subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTLVQILLASVSALLAEALVLKLRKQSVAATLKDNSALL
TGLLLAVSIPPLAPWWMVVLGTVFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQ
VIFSGHTASGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEQIMQYPIYSGILAGAGWQWVNLAWLAGGVWLLWQKAI
RWHIPLSFLVTLALCATLGWLFSPETLAAPQIHLLSGATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGY
PDGVAFAVLLANITVPLIDYYTRPRVYGHRKG
>SEQF1516_EDU84620.1 transcriptional regulator Mic [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAPASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVV
ETEAWHYLSLRISRGEIFLALRDLSSKLVVEESQELALKDDSPLLDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTE
NGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQVVIDHNVGAGVITDGHLLHAGSS
SLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILELAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGA
HVGRILAIMVNLFNPQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKDAMYNGSLL
IRLLQG
>SEQF1516_EDU84621.1 NAD(P) transhydrogenase, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIGIPRERLTNEPRVAATPKTVEQLLKLGFTVAVESGAGQLASFDDKAFVQAGAEIVEGNSVWQSEIILKVNAPLDDEI
ALLNPGTTLVSFIWPAQNPELMQKLAERNVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGCFFTGQITAA
GKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGSGDGYAKVMSDAFIKAEME
LFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMKAGSVIVDLAAQNGGNCEYTVPGEIFTTENGVKVIGYTDLPGRLP
TQSSQLYGTNLVNLLKLLCKEKNGNITVDFDDVVIRGVTVIRAGEITWPAPPIQVSAQPQVAQKAAPEVKTEEKCACSPW
RKYALMALAIILFGWLASVAPKEFLGHFTVFALACVVGYYVVWNVSHALHTPLMSVTNAISGIIVVGALLQIGQGGWVSF
LSFIAVLIASINIFGGFTVTQRMLKMFRKN
>SEQF1516_EDU84622.1 twin-arginine leader-binding protein DmsD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWETQWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPW
ALPSPPWGSVWLDRESVLFGDSTLALRQWMREKGIQFEMKQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR
>SEQF1516_EDU84623.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIENHLYSLVTDVKYKLLPCLLAILLTGCDRTEVTLSFTPEMASFSNEFDFDPLRGPVKDFTQTLMDEQGEVTKRVSGTL
SEEGCFDSLELLDLENNTVVALVLDANYYRDAETLEKRVRLQGKCQLAELPSAGVSWETDDNGFVIKASSKQMQMEYRYD
DQGYPLGKTTKSNDKTLSVSATPSTDPIKKLDYTAVTLLNNQRVGNVKQSCEYDSHANPVGCQLIIVDEGVKPAVERVYT
IKNTIDYY
>SEQF1516_EDU84624.1 anaerobic dimethyl sulfoxide reductase, A subunit YnfE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKNERMVGISRRTLVKSTAIGSLALAAGGFSLPFTLRSAAAAVQQASEQVVWGACSVNCGSRCALRLHVKDNEVAWVET
DNTGSDEYGNHQVRACLRGRSIRRRINHPDRLNYPMKRVGKRGEGKFERISWDEALDTIASSLKKTVEQYGNEAVYIQYS
SGIVGGNITRSSPSASAVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTTDIENSKLVVMFGNNPAETRMSGG
GITYLLEKSREKSNAKMIVIDPRYTDTAAGREDEWLPIRPGTDAALVAGIAWVLINENLVDQPFLDKYCVGYDEKTLPAD
APKNGHYKAYILGEGDDKTAKTPQWASQITGIPVDRIIKLAREIGTAKPAYICQGWGPQRQANGELTARAIAMLPILTGN
VGISGGNSGARESTYTITIERLPVLDNPVKTSISCFSWTDAIDHGPQMTAIRDGVRGKDKLDVPIKFIWNYAGNTLVNQH
SDINKTHEILQDESKCEMIVVIENFMTSSAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFLQPVTSEKFERKPIYWIL
SEVAKRLGPDVYQKFTEGRTQEQWLQHLYAKMLAKDPALPSYDELKKMGIYKRKDPNGHFVAYKAFRDDPEANPLKTPSG
KIEIYSSKLAEIARTWELEKDEVISPLPVYASTFEGWDSPERSTFPLQLFGFHYKSRTHSTYGNIDVLKAACRQEVWINP
IDAQKRGIANGDMVRVYNHRGEVRLPAKVTPRILPGVSAMGQGAWHEANMSGDKIDHGGCVNTLTTLRPSPLAKGNPQHT
NLVEIEKI
>SEQF1516_EDU84625.1 electron transport complex protein RnfC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFVIPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLP
VHAPTSGTVTAIAPHSTAHPSALAELSVIIDADGEDCWIPRDGWADYRSRRREELIERIHQFGVAGLGGAGFPTGVKLQG
GGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKPQAISMLRAVLADSHDISMRVIP
TKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNVGTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRH
LLNDAGFCPSADQMVIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLLPQQLYWFS
KGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEEKRAAEAKARFEARLARLEREKAARLERHKS
AAVQPAAKDKDAIAAALARVKEKQAQATQPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVTDPRKTAVE
AAIARAKARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQA
NAEPEEPVDPRKAAVEAAIARAKARKLEQQQANAEPEEPVDPRKAAVEAAITRAKARKLEQQQANAEPEEQVDPRKAAVA
AAIARAKARKLEQQQANAEPEEQVDPRKAAVAAAIARVQAKKAVQQKVVNED
>SEQF1516_EDU84626.1 putative phage excisionase protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEVIMIVSPGKWVSEEQLIALKGIKKGTLKKAREKSFMEGREYKHVAHDGMPWDNSPCFYNLEEIDRWIERQASARPRR
HLT
>SEQF1516_EDU84627.1 multidrug resistance protein MdtJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLSYIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLF
DESLSLMKIAGLTTLVAGIVLIKSGTRKARKPELEVNHGAV
>SEQF1516_EDU84628.1 transcriptional regulatory protein RstA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTIVFVEDDAEVGSLIAAYLAKHDIQVTVEPRGDQAEETILRENPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTS
LDSDMNHILALEMGACDYILKTTPPAVLLARLRLHLRQNEQATLTKGLQETSLTPYKALHFGTLTIDPINRVVTLANTEI
SLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAAEPYRIKTVRNKGYLFAPHAWE
>SEQF1516_EDU84629.1 fumarate hydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSLIHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEV
LAGQHDDEFPLAIWQTGSGTQSNMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQL
IPQLKTLTQTLSEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYSLPHVAELALGGTAVGTGLNTHP
EYARRVADELAVITCAPFVTAPNKFEALATCDALVQAHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSI
MPGKVNPTQCEALTMLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIEPNRERINQ
LLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEFDSWVRPEQMVGSMKAGR
>SEQF1516_EDU84630.1 dethiobiotin synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGSKETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEE
ESSVAHSCPINYTLISNGLANLTEKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIA
NDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLAMLRSVLAVDRVTV
>SEQF1516_EDU84631.1 multidrug resistance protein MdtI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAAVLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAG
WILFGQRLNRKGWIGLVLLLAGMIMVKLA
>SEQF1516_EDU84632.1 crossover junction endodeoxyribonuclease RusA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIDLVLPYPPTVNTYWRRRGSTYFVSKAGERYRRAVALIVRQQRLKLSLSGRLAIKIIAEPPDKRRRDLDNILKAPLDA
LTHAGLLMDDEQFDEINIVRGKPVSGGRLGVKIYPIMLEGQVKK
>SEQF1516_EDU84633.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFIHQLMLYFCTVVCVLYLLSGGYRAMRDFWRRQIDKRAAEKISASQSAGSKPEEPLI
>SEQF1516_EDU84634.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWYMDIDTTANYKLGGAQQHDSVRLDPWVFMFSAGYRF
>SEQF1516_EDU84635.1 prophage minor tail protein Z [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIKGLAQAMKNLDAIDRRAVPRASATTLNRVAGAIIAKTASSVARELAVPRRLIRARIRLSPARPDKVYAKVYINTGNL
PAIKLGEARVRLSRRKRRKKGQRAALKGGGSVLIVGKRRIPDAFITRLANGRWHVMQRMPWASSSTGADSKGRPKRHRLP
IEVVKITTAGPLAETFERERDRMYREKLPAQMMKAMTHQLRLVLKRK
>SEQF1516_EDU84636.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHSKSINRYYVHVQLFEATMEQEKKFETLMPNFKYSRMINEGDIEYKLLPGAYVIQSTLNANQILEQTFSIANSVGANAH
IFVCPYDESATLLPCADFSTY
>SEQF1516_EDU84637.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDVATVRVMGKQAEINGVVYDVMPEEESAEMGALSGSQLSLVVFSARYRPARHDVVVFAGRTLTVTRYDTYNGKPRIFVE
QE
>SEQF1516_EDU84638.1 IS1 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVCAEMDEQWGYVGAKSRQRWLFYAYDRIRRTVVAHVLGERTLATLERLLSLLSAFEVVVWMTDGWPLYESRLKGKLHV
ISKRYTQRIERHNLNLRQHLARPGRKSLSFSKSVELHDKDIGHYLNIKHYQ
>SEQF1516_EDU84639.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVQFSTGFPVPSFSTPEIFTAIFTPQKSPPEPAGCHNTVLPG
>SEQF1516_EDU84640.1 hypothetical protein ECH7EC4501_5248 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDKELIAALSIPGNYEVIVLGNGEFIVMPLPSDVILISKESHADSVSYFSIKRD
>SEQF1516_EDU84641.1 tryptophan synthase, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADTLELGIPFSDPLADGPTIQNATLRAFAAGVTPAQ
CFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADD
DLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKI
IEQHINEPKKMLAALKAFVQPMKAATRS
>SEQF1516_EDU84642.1 HTH-type transcriptional regulator CysB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDELGIQIFSRSGKHLTQVTPAGQEIIRIAREVLSKVDAI
KSVAGEHTWPDKGSLYIATTHTQARYALPNVIKGFIERYPRVSLHMHQGSPTQIADAVSKGNADFAIATEALHLYEDLVM
LPCYHWNRAIVVTPDHPLAGKKAITIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTPRIVFTATDADVIKTYVRLGLGV
GVIASMAVDPVADPDLVRVDAHDIFSHSTTKIGFRRSTFLRSYMYDFIQRFAPHLTRDVVDAAVALRSNEEIEVMFKDIK
LPEK
>SEQF1516_EDU84643.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMNAWARPDGEKVPAAGITQAYFELGMTFPELYDDSHPEALARNTQKIFRWVEKDTPDAVEKMQALLPAIEKAMPPLLV
ARMRSHSSEYYREIVERRDRLVKDVDDFVASAVVLYDQMNRGGPAGNAVVMH
>SEQF1516_EDU84644.1 phage minor tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTFRWKVKPDMEVNSQPSVREVRFGDGYSQRMAAGLNADLKTYRVTLSVTREEARHLEAFLAEHGGWKAFLWKPPYAYR
QIKVTCAGWSARVGMLRVEFSAEFKQVVN
>SEQF1516_EDU84645.1 putative prophage tail fibre C-terminus family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNILKKLMQRLCGCGKHDDRENGELLTAQLRLGPADILESDENGIIPEQARVITQVVILDADKKQIQCVVRPLQILRADG
TWENIGGMK
>SEQF1516_EDU84646.1 tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGATGPQGPKGDPGETQIRFRLGPGNIIETNSNGWFPDTDGALITGLTFLDPKDATRVQGFFQHLQVRFGDGPWQDVKGL
DEVGSDTGRTGE
>SEQF1516_EDU84647.1 putative exclusion protein ren of cryptic prophage CP-933P [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKPFTHEQREELKARIIGLVRKNERMTISQLERATGAGWHSVRRCLVDVLACGDLYMPGKYGVFTSEQVYRVWRKAAEK
TTDQTLIRKLPDGEIRRYDRQQNIICGECRKSEVMLRVLAFYQGNFQEAVL
>SEQF1516_EDU84648.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSPPGRPSVPEVRLPPPGQPHLFLLSVPVGLPGLPHRYLPLDPVDLHFPSDRSLPALPCHLSAPAGLPDQHHLPVPVRRL
PRQGRCLHALLYLPSAPEDPRAPVPPLAREVPPRWGFGLRPLPPLSCFVPLTVRFLLTPGLFLLRSLHPWMHYRLHFLPS
FLTIQLLLHFVMTHWLFERPQRPRTRTPPLTALQRLHFLPPAGLTPMHPLLKCQHLQRSLLPDWLICRHSSLMSPPLRHS
SSPPRRDALLLPPSVQNDAVPPAGHHPPTWHRENHSASPVENLHTR
>SEQF1516_EDU84649.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEHRGGSGNFAEDREKASDAGRKGGQHSGGNFKNDPQRASEAGKKGGQQSGGNKSGKS
>SEQF1516_EDU84650.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGKFRCILLLIVGLFFSSLSYAKNTEMPSYEEGISLFDVEATLQPDGVLDIKENIHFQARNQQIKHGFYRDLPRLWMQP
DGDAALLNYHIVGVTRDGIPEPWHLDWHIGLMSIVVGDKQRFLPQGDYHYQIHYQVKNAFLREGDSDLLIWNVTGNHWPF
EIYKTRFSLKFPDIAGNPFSEIDLFTGEEGDTYRNGRILEDGRIESSDPFYREDFTVLYRWPHSLLSNAPAPQTTNIFSH
LLLPSTSSLLIWFPCLFLVCGWLYLWKRRPQFTSVDVLRMQKFYLPRKKSSFYRPDTFLQWGGLAILAVILYGNLSPVGW
AGMSLVGDMFIMICWLLPFLFCSLELLFARDDDKPCVNRVIITLFLPLICSGVAFYSLYINVGDVFFYWYMPAGYFSAVF
LTGYLTGMGYIFLPKFTQTGQQRYAHGEAIVNYLARKEAATHSGRRRKGETRKLDYALLGWAVSANLGREWVARITPSLT
AAVRAPEIARSGVLFSLQMHLSLGANTSLLGRSYSGGAAGGGGGGGW
>SEQF1516_EDU84651.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKQQDMTETARAVFNELSVTEPATVGEIAQNTYLSRERCQLILTQLVMAGLADYQFGCYRRLQS
>SEQF1516_EDU84652.1 major tail protein V [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATPNPLEPVKGAGTTLWVYNGKGDAYANPLSDDDWQRLAKVKDLTPGEMTAEPYDDNYLDDEDADWTATGQGQKSAGDT
SFTLAWKPGEEGQKGLIGWFESGDVRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGKPSVAEERSEITP
ATAIKVTPTSGTVAKGKTTTLTVSFEPESATDKTFRAVSADPSKATISVKDMTITVNGVATGKVQIPVVSGNGQFAAVAE
VTVTEAGAAG
>SEQF1516_EDU84653.1 cob(I)yrinic acid a,c-diamide adenosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDERYQQRQQRVKEKVDARMAQAQDERGIIIVFTGNGKGKTTAAFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPH
GVEFQVMATGFTWDTQNRESDTAACREVWQHAKRMLADSSLDLVLLDELTYMVAYDYLPLEEVLQALNERPHQQTVIITG
RGCHRDILELADTVSELRPVKHAFDAGVKAQIGIDY
>SEQF1516_EDU84654.1 anthranilate synthase, component II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADILLLDNIDSFTYNLADQLRSNGHNVVIYRNHIPAQTLIERLATMSNPVLMLSPGPGVPSEAGCMPELLTRLRGKLPI
IGICLGHQAIVEAYGGYVGQAGEILHGKASSIEHDGQAMFAGLTNPLPVARYHSLVGSNIPAGLTINAHFNGMVMAVRHD
ADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPTNTLQPILEKLYQAQTLSQQESHQLFSAVVRGELKPEHLAAALV
SMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADIVGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSD
LLAAFGINLDMNADKSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGVYSPELVLP
IAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDFGLTPYHQEQLAGGTPEENRDILTRLLQGKG
DAAHEAAVAANVAMLMRLHGHEDLQANAQTVLEVLRSGSAYDRVTALAARG
>SEQF1516_EDU84655.1 DNA replication protein DnaC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNITSGGVLARISRFVPQDAIPPYRTVAEWREWQLAEGRKRSEEVNRLNHQTRVEKIINRSGIQPLHRKCTFCNYRVQN
AGQRHALSQAKSIAAELEGGCTNFVFSGRPGTGKNHLAAAIGNRLMEKGRSVIIITVSDVMSVLHDSYDNGKSGEKFLQE
LCGVDLLVLDEIGMQRDTRNEQVTLNQIVDRRTASLLSVGMLTNLNHAAMNTLLGERVMDRMSMNGGRWVTFNWESWRPN
VSQHRN
>SEQF1516_EDU84656.1 hypothetical protein ECH7EC4501_5217 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKINVMELFFRHQKSNAASLLRLQAIAGNVKSFRNFIPS
>SEQF1516_EDU84657.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDRELKNLHLNISQLAALSGAHRQTVAARVKNISPAGGHESNLKLYRLTDILAELMKAPLPVDNEEMDPHARKAWYQSER
DRLKFEQETGQLVPVSDVRRSFSVVVKAIVQVLETWPDRLERDRGWTASQLNEVQIVVDEIRDTLEKAVIDCCDEADM
>SEQF1516_EDU84658.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEITSLVTAEAVKEVLRSEEVLSALKQKLRHNLEARLDAEVDAILDELLGVQAEPPTEAGDTTAESGEVQPESPVADAT
EPQPESVMML
>SEQF1516_EDU84659.1 phage terminase large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQVNESHSRASDIWREVASLFRPPSRLPVAEAIRRYMRVPRGANTSGPWESSLTPYMIDPINTLSAREYDAVVFVGPAR
TGKTEGLIDGWIVYGIICDPADMLVVQMTETKAREHSRTRLSRTFRHSPEVSKRLSPSRNDNNVHDKMFLDGSFLKIGWP
SITVFSSSDYRRVALTDYDRFPENVDGEGDAFTLASKRTTTFMSSGMTLVESSPGRDITDTKWRCGGAHEAPPTTGILSL
YNRGDRRRWYWPCPHCGEYFQPVMDNMTGYRNNPDFVAAGQAARLMCPHCRGLIAPEQKRELNNQGIWLREGERAAADGS
ITGTPRNSRIASFWMEGPAAAFQTWEQLIFKLLAAEEEYERTGSEETLKAVVNTDIGRPYLPRSATEQRKSELLEQRAEP
FPRRSVPDGVRFIEATVDVQGGKNRRFVVQITGYGEQGERWIVDRYNIRHSLRCSPNGESLPVDPAAYPEDWDLLLTDVF
HKTWPLASDPDVRMRLMAMAVDTGGEAGVTDNAYRFWRRCRSDGLGNRVFLFKGDGLRRDRLINRTFPDNTGRSARRARA
SGDVALWLVQTDAFKDRVNNALWRDTPGPNYIHFPDWLGRWFYDELTYEERGSDGKWRKPGRGANEAFDLLVYADALAVL
HGYEKIRWPSAPDWAQRETWLVFPQERSGETVSPELTAGAEKRRRRKKKLRTERAEDNPWITSGGWL
>SEQF1516_EDU84660.1 YjhS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFKHYDVVRAASPSDLADALAQKIREGWQPYGGPFSSYTDDGAALIQAIVAEGDVSTPVVVKPTGGEGAVISATSDPEY
YFVVVLAGQSNSMAYGEGLPLPETYDRPDPRIKQLARRSTVTPGGVACKYNDIIPADHCLHDVQDMSRLNHPKADLSKGQ
YGTVGQGLHIAKKLLPFIPANAGILLVPCCRGGSAFTTGADGTYSDASGASENSTRWGVDKPLYKDLIGRTKAALKKNPK
NVLFAVVWMQGEFDFGGTPVNHAAQFGALVDKFRADLADMAGQCVGGSAGGVPWICGDTTYFWKQKNESTYQTVYGSYKN
KTEKNIHFVPFMTDENGVNVPTNKPEEDPDIPGIGYYGSKWRDSSATWTSQDRASHFSAWARRGIISDRLATAILRHAGR
VALNAGASSTVSEVRPSSPSGAEATGVTTLLSYLASESEGSLKVQGWSASGGRAEVVSDAEGTGGKAVKLTKEAGKSSWV
LEYAAGNGAALLQKGGQIRCRFKVSGALAANQYVMAFYWPVSSLPQGVALTGDGGNNLLAAFYIQTDAKDLNVMYHNAKV
ATNNLKLGTFGAFDNEWHTLAFRFAGNNSLQVTPVIDGQDGTPFTLTQSPVSAFAADKLHVTDITRNATYPVLIDSIAVE
VNNADAAA
>SEQF1516_EDU84661.1 host specificity protein J [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKGGGKGHTPVEAKDNLKSTQMMSVIDAIGEGPIEGPVKGLQSILVNKTPLTDTDGNPVIHGVTAVWRAGEQEQTPPEG
FESSGAETALGVEVTKAKPVTRTITSANIDRLRVTFGVQSLLETTSKGDRNPSSVRLLIQLQRNGNWVTEKDVTINGKTT
SQFLASVILENLPERPFNIRMVRETADSTSDQLQNKTLWSSYTEIIDVKQCYPNTAIVGLQVDAEQFGGQQMTVNYHIRG
RIIQVPSNYDPEKRTYSGIWDGSLKPAYSNNPAWCLWDMLTHPRYGMGKRLVAADVDKWALYAIGQYCDQTVPDGFGGTE
PRMTFNAYLSQQRKAWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDVVWPYTNSDVVVDDNGVGFRYSFSALKDRHTAVE
VNYTDPQNGWQTSTELVEDPEAILRYGRNLLKMDAFGCTSRGQAHRAGLWVIKTGLLETQTVDFTLGSQGLRHTPGDIIE
ICDNDYAGTMTGGRILSIDAASRTLTLDREVTLPETGAATVNLINGSGKPVSVAITAHPAPDRIQVSTLPDGVETYGVWG
LSLPSLRRRLFRCVSIRENTDGTFAITAVQHVPEKEAIVDNGASFEPQSGTLNSVIPPAVQHLTVEVSAADGQYLAQAKW
DTPRVVKGVSFMLRLTVVADDGSERLVSTARTTETTYRFTQLALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSQIE
LTPGYFQITAVPRLAVYDPTVQFEFWFSETRITDIRQVETTARYLGTGLYWIAASINIKPGHDYYFYIRSVNTVGKSAFV
EAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITDVSNEITQTVNKKLEDQSAAIQQIQKVQV
DTNNNLNSMWAVKLQQMKDGRLYIAGIGAGIENTPAGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNDVFLKRL
TAPTITSGGNPPAFSLTPDGKLTAKNADISGSVNANAGTLNNVTINENCQIKGKLSANQIEGDIVKTVGKAFPRDSRAPE
RWPSGTITVRVYDDQPFDRQIVIPAVAFSGAKHEREHTDIYSSCRLIVRKNGAEIYNRTALDNTLIYSGVIDMPAGHGHM
TLEFSVSAWLVNNWYPTASISDLLVVVMKKATAGISIS
>SEQF1516_EDU84662.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVLLRPVLVPELGLVIVKPGRESMSVFHNGRILVEPEPKNMRGLPSGVVPAVRQPLAEDKTLLPFFSDERVIRAAGGAG
ALSDWLLRHVKSCQWPHGDYHHSETVIHRYGTGAMVLCWHCDNQLRDQTSESLDQLAQQNLVAWMIDVIRHAISGTQERE
LSLAELSWWAACNQVVDALPEAVARRSLGLPAEKIRSVYRESDIVPGEQTAISILKQRTKNIALPLHVHQQQNPPQKKTV
VSIAVDPESPESFMKRPKRRRWVNEKYTRWVKTQPCACCGKPADDPHHLIGHGQGGMGTKSHDIFTLPLCREHHNELHAD
PLAFEEKHGSQVDLIFRFLDHAFATGVLG
>SEQF1516_EDU84663.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIISTVIQTPFPFENNNSHTGVVTEPILGKLIGQGSTAEIFEDMNDSSALYKKYDLVGNQHNEVLEMARQESALFNTFY
GDDASVVIQYGGDVYLRMLRVPGIPLSDIDTADIPDNLESLYLQLICKLNELSIIHYDLNTGNMLYDKESNSLFPIDFRN
IYSEYYSATKNDKEIIDRRLQMRTNDFYSLLNRKYL
>SEQF1516_EDU84664.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDTLNLGNNESLVYGVFPNLDGTFTAMTYTRSKTFKTEAGARRWLARNTD
>SEQF1516_EDU84665.1 phage O protein family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFGGFMSSKLHGLVWEGCAFTGMILSRVAVMARLADYSNDEGVSWPAIETIRRQIGARSESTVKSAIAELAKEGWLTKEE
RKVGGRNVSNIYRLNVEKLEAAAAAAREAYKPKRKISQAKNDPSNIAPSTVGPSNVDGSTVDKKLRIRGAMIDPDPSVLK
PDPSDKRSSCPDVSLPDEKQSSPVERFLEKHPDAHTWNVPKRQWGTREDLTCAQWIWGRVVALYEQAASDDGEVSRPREP
NWTTWANDVRMMRMLDGRSHRQICEMFGRVQRDSFWVKNIMSPAKLREKWDELVIRLGRSPAQRCVNHISEPDTEIPPGF
RG
>SEQF1516_EDU84666.1 bacteriophage lambda tail assembly protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTAAEAIRALSLQMPRFRRQMNEGWYQIRIRGEDTAPEAVYARLHEQLGEGTVIHIVPRLAGAGKGGLQIVLGAAAIVG
SFFTAGASMALWGSALAAGGFSATTMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGRQNTYFSSLDNMIAQGNPMPVP
YGEMLVGSRRISQDISTRDEGGDGKVVVIGRG
>SEQF1516_EDU84667.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEIKPEDELSNIVLFPVKEDDPRNQVNFLYEPSERAYCHHASVRVDEKERQVRCKICGAVVEPFDWMLSVAKRETRLADD
VRILRQEERERRRNIEKLIQIERNVKARIRRVTKSRTE
>SEQF1516_EDU84668.1 putative bacteriophage CI repressor protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDMRKKQYDTPLAERLDTISQQHHLSGSDLARIAGVGRSSVNAWKKRGTISKDSAAKIAEATNVSLSWLLTGKEDTNREA
LDDDEKALLDVYRNLPPVERRNMLAAFQMRLQKLTEFYSEYVDPITRQK
>SEQF1516_EDU84669.1 phage minor tail protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDIHEESLNESVKSEQSPRVVLWEIDLTAQGGERYFFCNELNEKGVPVTWQGREYQAYPIEGSGFEMNGKGSSARPSLT
VSNLFGLVTGMAEDLQSLVGATVVRRRVYARFLDAVNFVAGNPEADPEQELTDRWVVEQMSELTAMTASFVLATPTETDG
ALFPGRIMLANTCMWDYRGDECGYNGPAVADEFDNPTTDIRKDRCSKCMRGCEMRGMVANFGGFLSINKLSQ
>SEQF1516_EDU84670.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGVKTFAGIHTKGGNMSDDISLAMEGALAVIAVVGVYCLVVFLMDRLGN
>SEQF1516_EDU84671.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFKDLPMQFQEMAANIVRSQLATLDLSTVEKETIDNISHNVRNSFIKLYEENLSSENKDDSPKFTPHPGGVSEIYHETM
VKALRMQIAELEHKLNLVSKC
>SEQF1516_EDU84672.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVEIMEIAMRKAGNSPVTPDGWISCSERMPNTKTAVLVAVEFDRKGDWRMKWATYIPGHPDANDGWIIPGASWKPSHWMP
LPEPPQEVRQ
>SEQF1516_EDU84673.1 hypothetical protein ECH7EC4501_5242 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHMVNRHVAKPLSGGAFFMGKKSPRWETRAARNKQQNVK
>SEQF1516_EDU84674.1 enterobacterial Ail/Lom family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKLYAAILSAAICLAVSGAPAWASEHQSTLSAGYLHVSTNVPGSDELNGINVKYRYEFTDTLGMVTSFSYAGDKNRQLT
RYSDTRWHEDSVRNRWFSVMAGPSVRVNELFSAYAMAGVSYSRVSTFSGDYLQVTDNKGKTHDVLTGSDDGRHSNTSLAW
GAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF
>SEQF1516_EDU84675.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKETQPIDRETLLKEANKIIREHEDTLAGIEATGVTQRNGVLVFTGDYFLDEQGLPTAKSTAVFNMFKHLAHVLSEKYH
LVD
>SEQF1516_EDU84676.1 peptidase, S49 (protease IV) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQRNKRQRGELRVNNLSEQYKEMKEELAAALMDSHQQKQWHKAQKKKHK
QEAKAAKAKAKLGEVSTDSKPRVWVLDFKGSMDAHEVNSLREEITAVLAAFKPQDQVVLRLESPGGMVHGYGLAASQLQR
LRDKNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQMPNFNRFLKSKDIDIELHTAGQYKRTLTLLGENT
EEGREKFREELNETHQLFKDFVKRMRPSLDIEQVATGEHWYGQQAVEKGLVDEINTSDEVILSLMEGREVVNVRYMQRKR
LIDRFTGSAAESADRLLLRWWQRGQKPLM
>SEQF1516_EDU84677.1 tryptophan biosynthesis protein trpCF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTVLAKIVADKAIWVEARKQQQPLASFQNEVQPSTRHFYDALQGARTAFILECKKASPSKGVICDDFDPARIAAIYKHY
ASAISVLTDEKYFQGSFDFLPIVSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLKMGV
LTEVSNEEELERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGINTYAQVRELSHFADGFLIGSALM
AHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAGAIYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVL
DKAKVLSLVAVQLHGNEDQLYIDTLREALPAHVAIWKALSVGETLPARELQHVDKYVLDNGQGGSGQRFDWSLLNGQSLG
NVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTLRAY
>SEQF1516_EDU84678.1 tail assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNISAEPEAYFRIAPEDWLQAEMQGEIVALVHSHPGGLPWLSEADRRLQIKSALPWWLVCRGEIHKFRCVPHLTGRRFEH
GVTDCYTLFRDAYHLAGITLPDFVREDDWWRNGQNLYLDNMAATGFYRVPLSSAQAGDILLCCFGASVANHAAIYCGNGE
LLHHLPEQLSKRERYSEKWQRRTHSVWRHRHWHASAFTGICNDLAAASACT
>SEQF1516_EDU84679.1 tryptophan synthase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQFNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDL
LHGGAHKTNQVLGQALLAKRMGKTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH
SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILEREGRLPDAVIACVGGGSNAIGM
FADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRVGIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTG
RADYVSITDDEALEAFKTLCLHEGIIPALESSHALAHALKMMRENPEKEQLLVVNLSGRGDKDIFTVHDILKARGEI
>SEQF1516_EDU84680.1 putative phosphoesterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDTNYAVIYDLHSHTTASDGCLTPEALVHRAVEMRVGTLAITDHDTTAAIAPAREEISRSGLALNLIPGVEISTVWENH
EIHIVGLNIDITHPLMCEFLAQQTERRNQRAQQIAERLEKAHIPGALEGAQRLAQGGAVTRGHFARFLVECGKASSMADV
FKKYLARGKTGYVPPQWCTIEQAIDVIHHSGGKAVLAHPGRYNLSAKWLKRLVAHFAEHDGDAMEVAQCQQSPNERTQLA
TLARQHHLWASQGSDFHQPCPWIELGRKLWLPAGVEGVWQLWEQPQNTTEREL
>SEQF1516_EDU84681.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNFVQDGTTIELVNAGDQTILSGAAVVVGSMVAVAITDIPAGEAGDGFAEGVFLLPKQSADDIQSGAVVYLKDGVVQL
AADGAVAAGVAWENAPANSATVAVKINV
>SEQF1516_EDU84682.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRVLCVVIIALLVACGALSLGLNHYRDNAITYKEQRDKKVSELELANATITDMQQRQRDVAALDARYSRELADARAENE
TLRADVAAGRKRLRINATCSGTVREATGTSGVDNATGPRLADTAERDYFILRERLMTMQKQLEGAQEYIRTQCTKLAFYY
PEDT
>SEQF1516_EDU84683.1 peptidase S14, ClpP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQAGGPGDADIYIYDEIGFWGVTAKQFVSELNALGDITHINLHINSPGGDVFEGIAIFNALKNQGATITVYVDGVAASMA
SVIAMAGDTVIMPENAFMMIHKPWGFSGGDAEDMRSYADLLDKVESVLLPAYAQKTGKTTDEIAAMLADETWMSGAECLA
HGFADQVTPAVEAMACIQSKRTEEFKKMPESIRNMITPPRNSAPRDTTVTIPAPAVTEPSPVPAVSDEATIRARVMAEQK
ARMSGINDLFAMFGGRYQTLQAQCVADPDCSLEMARERLLNEMGKESSPTNKNTPAHIYAGNGNFVGDGIRQAMLARAGF
ENVEKDNAYNGMTLREWARMSLTERGIGVASYNPMQMVGLALTHSTSDFGNILLDVSNKGLIQGWEESEETFQKWTRKGR
LSDFKTAYRVGMGGFGSLRQVREGAEYKYITTSDRKETIALATYGEIFSITRQAIINDDLNMLVDVPMKMGRAAKATIGD
LVYKVLTDNPKLSDGKALFHADHKNIATGGISVSGLDAARQMMRLQKEGDRALNIRPAFMLVPVALETVANQTIKSASVK
GADANAGVINPIQNFAEVIAEARLDAADPKTWYLAAAQGTDTIEVAWLDGVDTPYIDQQEGFTTDGIATKIRIDAGVAPL
DWRGLVRSSVA
>SEQF1516_EDU84684.1 YciF protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISLEKNMNMKTIEDVFIHLLSDTYSAEKQLTRALAKLARATSNEKLSQAFHAHLEETHGQIERIDQVVESESNLKIKRM
KCVAMEGLIEEANEVIESTEKNEVRDAALIAAAQKVEHYEIASYGTLATLAEQLGYRKAAKLLKETLEEEKATDIKLTDL
ALNNVNKKAENKA
>SEQF1516_EDU84685.1 phage minor tail protein U [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHREIRAAVLSALKENISERVSWFDGRPVFIDEQELPAVAVYLTDASAADEFVDEGTWEATLHIEVFLRAKEPDSALDM
WMEEKILPALEAVPGLSALLLKMNLQGYDYRRDDEFMMWGSADLLWKITYEM
>SEQF1516_EDU84686.1 hypothetical protein ECH7EC4501_5202 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRISQIKRNEKKVGKYIMTNVLDILTIACGISDLEKIIDFTGVMLRD
>SEQF1516_EDU84687.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLRVTVEPFQGTIPFRILQRGRVLVEGSFSGKCTQLHSRTFQVNATNEELTVECTMNAAKCRMVSAALQPVC
>SEQF1516_EDU84688.1 minor tail protein H [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGNFADLTAVLTLDSARFSEEAARVKKELGETSALADLMSGKVSQSFRKQADAAEQSLSRQALAAQKAGISVGQYKAAM
RTLPAQFTDIVTQLAGGQNPFLIMLQQGGQISDSFGGPLSLLTLLKEELLGIRDASESSEESLSDTANALAENARNAGEL
GRFMSVARVAAGGGVAVLAALAAAAWQAEQADRALLRSLILTGGAAATTTAELWKMAGVISDEAGGGIRQAAENLARLAE
SGKYTAGQLRIMGETSQRWLQTVGDDAGKVEKAFEGIAADPVKALASLNQQYNFLSVSQLRHIDELERTKGKQAAVTEAM
SLFADVMNARLEQLDKAATPVEKIWDDVKTWTSDAWAWIGDHTLGALSLITDVVAGTVEQVKLLLVQGDLALAEFIQSAW
ETTKNVPGVGALFGELAEENRVFIEKTKRDELALRKSIAERDARIRQGEIGYINRSRATGVSKGPGQQEAVSRLAEELTG
KKHTSPKTRSAGEREEEQAREALLALEAELRTLEKHSGANEKISRQRRDLWKAESQYAVLKEAATKRQLSWQEKSLLAHE
KETLEYKRQLADLGDKVEHQKRLNELAQQAARFEQQQGAKQAAISAQARGLTDRQAQRESEEQRLRDVYGDNPDALAKAT
SALKNTWSAEEQLRGSWMAGLKSGWGEWAESATDSFSQVKSVATQTFDGIAQNMAAMLTGSEQNWRGFTRSVLSMLTEIF
LKQAMVGIVGSIGSAIGGAFGGGASASSGTAIEAAAANFHFATGGFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLY
RLMRGYAEGGYVGGAGSPAQMRRAEGINFNQNNHVVIQNDGTNGQAGPQLMKAVYDMARKGAQDELRLQLRDGGMLSGSG
R
>SEQF1516_EDU84689.1 anthranilate synthase, component I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTQKPTLELLTCEGAYRDNPTALFHQLCGDRPATLLLESADIDSKDDLKSLLLVDSALRITALGDTVTIQSLSGNGEAL
LTLLDNALPAGVENEQLPNCRVLRFPPVGPLLDEDARLCSLSVFDAFRLLQNLLNVPKEEREAMFFGGLFSYDLVAGFED
LPQLSAENNCPDFCFYLAETLMVIDHQKKSTRIQASLFAPNEEEKQRLTARLNDLRQQLTETAPPLPVVSVPHMRCECNQ
SDEEFGGVVRLLQKAIRAGEIFQVVPSRRFSLPCPSPLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDATSRQ
IEIYPIAGTRPRGRRADGSLDRDLESRIELEMRTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDRYSYVMHLV
SRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYGGAVGYFTAHGDLDTCIVIRSALVENGIATV
QAGAGVVLDSVPQSEADETRNKARAVLRAIATAHHAQETF
>SEQF1516_EDU84690.1 oxidoreductase, short chain dehydrogenase/reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGRNEEKLRQVASHINEETGRQPQWFILDLLTCRSEDCQ
QLAQRIAVNYPRLDGVLHNAGLLGDVCPMSEQNPQVWQDVIQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMTF
DAQPGRKPGISQ
>SEQF1516_EDU84691.1 phage minor tail protein G [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLKTEQFEYNGVSVTLSELSALQRFDYMKFVSDAEQQKTTKHDVVRINQRYLETASLLVAMSLWHSHSLKGTLASPETE
MQQIRREVMLGWPADALNQATNRVLYLSGMLDNRHDADPEPTGKTEATEPVTSKKHSKAS
>SEQF1516_EDU84692.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTEEAREMIQRYREAEMAVLEGKSVIFNGQQLTLESLSQIRAGRQEWERRLAAMVSRRRGKPGFKLARF
>SEQF1516_EDU84693.1 lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRKLRYGLSAAVLALIAAGASAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGATRVDGKPVIPGMKLSKEKCDQVNAI
ERDKALAWVEKNIRVPLTEPQKAGIASFCPYNIGPGKCFPSTFYRRINAGDRRGACEAIRWWIKDGGRDCRIRSNNCYGQ
VSRRDQESALACWGIDR
>SEQF1516_EDU84694.1 DNA methylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFNTVKISSCELINADCLEFIRSLPENSVDLIVTDPPYFKVKPEGWDNQWKGDDDYLKWLDQCLAQFWRVLKPAGSLYLF
CGHRLASDIEIMMRERFSVLNHIIWAKPSGRWNGCNKESLRAYFPATERILFAEHYQGPYRPKDAGYEAKGRALKQHVMA
PLISYFRDARAALGITAKQIVDATGKKNMVSHWFSASQWQLPDESDYLKLQALFARVAEEKHQRGELEKPHHQLLETYTS
LNRQYAELQSEYKHLRRYFGVTAQVPYTDVWTHKPVQYYPGKHPCEKPAEMLQQIISASSRPGDLVADFFMGSGSTVKAA
MALGRRATGVELETERFEQTVREVQDLVSQNG
>SEQF1516_EDU84695.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METVLHALKAMGKANSVELAARLDISREEVLNELWELKKNSVVDKTGHTWFLAGEGESGVTEERPVKSEAQDMLTREVEQ
KVTADMMIEFIGQDGAKTCEELAGKFGVSTRKVASTLAVVTATGRLARVNQNGKFRYCMPGDNLPAEPKAALVTESDGKA
FPQPAGAALPVREAATQEENKTETVAVTVQSQPLFTRKHPDGLILPSLHVANRELRRAKGQVQKWERVCAALRELNKHRD
IVRQIVDSSGRIVSEK
>SEQF1516_EDU84696.1 phage portal protein, lambda family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIIDDVIGVFSPGWKAARLRSRALIMAYEAVKPTRTHKARRENRSADQLSKYGAVSLREQARFLDINHDLVIGVFDKLE
ERVIGARGIIVEPQLLRKNGEMAAELAADIRRLWAEWSVSPDVTGQYTRPVLERLLLRTWLRDGEVFAQMVSGAGNGLER
TAGVPFWLEAMEPDFVPMRTDESAGLNQGVFLDEWGRPKKYLVYKNYPVRGRQSDTKEIAAGKMIHLKFTRRLHQTRGSS
MLSGVLMRISALKEYEDAELTAARIAAALGLYIRKGDGQDYEDPGSKETEREVHITPGIIYDDLRKGEDIGMVKSDRPNP
NLETFRNGQLRAVAAGSRLSFSSAARNYNGTYSAQRQELVESTDGYLILQDCFIGAVTRPVYRTWLNMVVAAGLLKIPAD
VEMKTLYNATYSGPVMPWIDPVKEAEAWRIQIRGGAATESDWVRAGGRNPDEVKRRRKAEIDENSRLGLVFDTDPVNDKG
GNSAGTERQYQRDTESQHEE
>SEQF1516_EDU84697.1 antitermination protein Q [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLEDLPKYYSPKSPGLTDASASTSKDALSITDVMAAQGMTQNRAEMGFSAFLGKMGISMNDRERATELLTEYALSRCDR
VAALRKLPAEIKPAVMRIMASYAFEDYARSAASKKQCPCCHGKKFIESEVFTNKIQYPDGKPPVWAKCTKGVYPSYWEEW
KKVREVVKVACPECGGKGEVSTACKDCRGRGVAIHREESVKRGMPVIRDCQRCGGRGCERLPSTEAFNAICNVTDAISLD
TWKKTVKRFYDTLVVQFDIEEAWAEQQLKKVTR
>SEQF1516_EDU84698.1 ribosomal large subunit pseudouridine synthase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEVTPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELC
TRNDPEGRPTVFDRLPKLRGARWIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGV
QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDIPLPKGLPRGGWTELDLAQTNYL
RELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHSQVSGGRRSGGRNNG
>SEQF1516_EDU84699.1 Sua5/YciO/YrdC/YwlC family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGTAAEHHREGIMSQFFYIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKIEDKNAMERICRIRQLPDGHNFTLM
CRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILKGTKEVPRRLLQEKRKTIGMRVPSNPIAQALLEALGEPMLSTSLMLP
GSEFTESDPEEIKDRLEKQVDLIIHGGYLGQKPTTVIDLTDDTPVVVREGVGDVKPFL
>SEQF1516_EDU84700.1 phage tail assembly protein T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAGMTSTEYADWRRFYCTHYFQDTQLDMHFSGLMYAVLSLFFCDPDMHPADFSLFAPEAEEGQAETPDENDVLMQKAAG
LAGGVRFGEEGRRL
>SEQF1516_EDU84701.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNAQKVINAEKYNEWVKKFSEQIFKITGDENAAKNELEPWTPEGVDPNYCWWDVDPVDAANEAMSYHND
>SEQF1516_EDU84702.1 DNA topoisomerase I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAAKKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWE
AHYEVLPGKEKVVSELKQLAEKADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNID
RVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEEFWEVDASTTTPSGEALALQVTH
QNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPTTSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYM
RTDSTNLSQDAVNMVRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQLIWRQFVA
CQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRILPAVDKGDALTLVELTPAQHFTKPPARFSEA
SLVKELEKRGIGRPSTYASIISTIQDRGYVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEW
KAVLDHFFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYALPPKERCKTTINLVPEN
EVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHVCGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHL
KMGRFGKYMACTNEECKNTRKILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVEEL
YRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYVDGKWVEGKK
>SEQF1516_EDU84703.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTELTKEKLIEEAKLKIAIAKCYPNSGMARVEGELFKIALASLEAEPIAWECGENIILFNPDTVEAYAKRAEISPKPLFS
APPALVVPDKLPREYRNGWPLAYSDYAEGWNDCREAMLQGDKS
>SEQF1516_EDU84704.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRIEHYHDWLRDAHAMEKQAESMLESMASRIDNYPELRARIEQHLSETKNQIVQLETILDRNDISRSVIKDSMSKMAAL
GQSIGGIFPSDEIVKGSISGYVFEQFEIACYTSLLAAAKNAGDTASIPIIEAILNEEKQMADWLIQHIPQTTEKFLIRSE
TDGVEAKK
>SEQF1516_EDU84705.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQMEKITTGVSYTTSAVGTGYWFLQLLDRVSPSQWAAIGVLGSLLFGLLTYLTNLYFKIREDRRKAARGE
>SEQF1516_EDU84706.1 PTS system, Fructose specific IIB subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKKLIALCACPMGLAHTFMAAQALEEAAVEAGYEVKIETQGADGIQNRLTAQDIAEATIIIHSVAVTPEDNERFESRDV
YEITLQDAIKNAAGIIKEIEEMIASEQQ
>SEQF1516_EDU84707.1 adenine methylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKKYTLIYADPPWTFRDKATDGQRGASFKYPVMSLLDICRLPVWELAAENCLLAMWWVPTQPLEALKVVEAWGFRLVTM
KGLTWNKCGKRQTDKLVMGMGSTTRANSEDCLFAVKGNLPERINAGIIQSFTAPRLDHSRKPDMAREKLVQLLGDVPRIE
LFARHTSHGFDVWGNQCGTPSIEMVPGIVKFLEKTNERKNDVDKGITS
>SEQF1516_EDU84708.1 multiphosphoryl transfer protein 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTIQFLCPLPNGLHARPAWELKEQCSQWQSEITFINHRQNAKADAKSSLALIGTGTLFNDSCSLNISGSDEEQARRVLE
EYIQVRFIDSDSVQPTQAELTAHPLPRSLSRLNPDLLYGNVLASGVGVGTLTLLQSDSLDSYRAIPASAQDSTRLEHSLA
TLAEQLNQQLRERDGESKTILSAHLSLIQDDEFAGNIRRLMTEQHQGLGAAIIRNMEQVCAKLSASASDYLRERVSDIRD
ISEQLLHITWPELKPRNNLVLEKPTILVAEDLTPSQFLSLDLKNLAGMILEKTGRTSHTLILARASAIPVLSGLPLDAIA
RYAGQPAVLDAQCGVLAINPNDAVSGYYQVAQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPGAFANGAEG
VGLFRTEMLYMDRDSEPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKSIPYLNIPQEENPFLGYRAVRIYPEFAGLFR
TQLRAILRAASFGNAQLMIPMVHGLDQILWVKGEIQKAIVELKRDGLRHAETITLGIMVEVPSVCYIIDHFCDEVDFFSI
GSNDMTQYLYAVDRNNPRVSPLYNPITPSFLRMLQQIVTTAHQRGKWVGICGELGGESRYLPLLLGLGLDELSMSSPRIP
AVKSQLRQLDSEACRELARQACECRSAQEIEALLTAFTPEEDVRPLLALENIFVDQAFSNKEQAIQFLCGNLGVNGRTEH
PFELEEDVWQREEIVTTGVGFGVAIPHTKSQWIRHSSISIARLAKPVDWQSEMGEVELVIMLTLGANEGMNHVKVFSQLA
RKLVNKNFRQSLFAAQDAQSILTLLETELTF
>SEQF1516_EDU84709.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPIPVETDEEFHTLATSLSQKLEMMAAKAEANERDPA
>SEQF1516_EDU84710.1 aminopeptidase YpdF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVLISRESAHILVDSRYYADVEARTQGYQLHLLDATHTLTTI
ARQIIADEQLQTLGFEGQQVSWETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSE
REIAAELEWFMRQQGAEKTSFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVSAESH
PLFNVYQIVLQAQLAAISAIRPGVRCQQVDEAARRVITEAGFSHYFGHNTAHAIGIEVHEDPRFSPRDTTTLQPGMLLTV
EPGIYLPGQGGVRIEDVVLVTPQGAEVLYAMPKTVLLTGEA
>SEQF1516_EDU84711.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTQVSVETLSTITYKQIPVITTELLAHLYGTEAIRIRQNHHENKGRFIEEKHFFKLEGETLREFKHRVAFNYSVKIARN
VRSLILWTERGAARHAKMLETDRAWEVFEKLEDCYFSQKIPEQLQLPESTLSINYPLSWFSEHHPYSMMSYVDRKTLNLD
VSVLFDMPSPTMRILNELHSKGYNVDAAVAEFNAFKHLTEEMRRTLQDISRLSDRNSRKGFSLSL
>SEQF1516_EDU84712.1 manganese transport protein MntH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQAGASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKN
LAEQIRDHYPRPVVWFYWVQAEIIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSSLTQHLHGGSRQQRYSATKWDVA
IAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAYLTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRF
HIPLWVRRTVTMLPSFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWVIVVLVVAL
NIWLLVGTALGL
>SEQF1516_EDU84713.1 hypothetical bacteriophage protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFVLIQRGQSFVDANNYPVEICKVTLTQVIYRRLDGRTRATSIGAFNEEFERIEHNELHMIKAEIEKEKHIASLRKMRRT
SIN
>SEQF1516_EDU84714.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEINYQALREKAEKATKGSYIVGHTSVNQHGNLTGVFVCQKWKGEPGGVIAECHVNCLIESDDQAYANAEFIAEANPAT
VLALLDEQERNQQYIKRRDQENEEIALTVGKLRVELEAAENNLIDSECHVAELEEALRDKQALLEASEKRNAKLQSENAY
IRNRYKELDLLIGKNILVMQAAIIEWQATGDAKSGLAWIYNTLFGPGELPDESEKDAQAYFNRKYAPIDEKLMALHKWFW
EQSEAERAAGIRIKRGE
>SEQF1516_EDU84715.1 positive transcription regulator EvgS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAIIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQVLETLRKRQYSGIIIIVS
AKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYFPFSLNRFVGSLTSDQQKLDSLSKQEISVMRYILDGKD
NNDIAEKMFISNKTVSTYKSRLMEKLECKSLMDLYTFAQRNKIG
>SEQF1516_EDU84716.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKTTLTKASPVELRQCLEIANQLARSGIRFVPIPITADAELHLFGEILSRKLDELEKLVEEADTSPTV
>SEQF1516_EDU84717.1 sucrose-6-phosphate hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKMTQSRLHAAQNALAKLHERRGNTFYPHFHLAPPAGWMNDPNGLIWFNDRYHAFYQHHPMSEHWGPMHWGHATSDDMI
HWQHEPIALAPGDENDKDGCFSGSAVDDNGVLSLIYTGHVWLDGAGNDDAIREVQCLATSRDGIHFEKQGVILTPPEGIM
HFRDPKVWREADTWWMVVGAKDPGNTGQILLYRGSSLREWTFDRVLGHADAGESYMWECPDFFSLGDQHYLMFSPQGMNA
EGYSYRNRFQSGVIPGMWSPGRLFAQSGHFTELDNGHDFYAPQSFVAKDGRRIVIGWMDMWESPMPSKREGWAGCMTLAR
ELSESNGKLLQRPVHEAESLRQQHQSISPRTISNKYVLQENAQAVEIQLQWALKNSDAEHYGLQLGTGMRLYIDNQSERL
VLWRYYPHENLDGYRSIPLPQRDTLALRIFIDTSSVEVFINDGEAVMSSRIYPQPEERELSLYASHGVAVVQHGALWQLG
>SEQF1516_EDU84718.1 hypothetical protein ECH7EC4501_4951 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQIAFYRRSGRPGAFRGLKERVTWMIQSRGRPVTGSEIAEKFGVSLCEFNKVARGLTKGSKVVKIKASEPFTTDTGIVD
RFFSLESNPRRDTPRSRNAVPPFSRRSREHAAKNCREEYVQKAERRRRLIKAGLYIDEFENAL
>SEQF1516_EDU84719.1 thiamine pyrophosphate-dependent enzyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAEGIRYIGFRHEQSAGYAAAASGFLTQKPGICLTVSAP
GFLNGLTALANATVNGFPMIMISGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPG
GVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKSVTSAISLLAKAERPLIILGKGAAYSQADEQLREFIESAQI
PFLPMSMAKGILEDTHPLSAAAARSFALANADVVMLVGARLNWLLAHGKKGWAADTQFIQLDIEPQEIDSNRPIAVPVVG
DIASSMQGMLAELKQNTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLVNEGANTLD
NARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAFGFSGMEIETICRYNLPVTIVIFNNGGIYRG
DGVDLSGAGAPSPTDLLHHARYDKLMDAFRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTESGHITKLNPKQ
VAGN
>SEQF1516_EDU84720.1 integrase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALSDTKLRGLYGKPYSGPAEITDGDGLSVRITPAGTITFQYRYRWNGKPVRLTVGRYPSTSLKDARVIVGEMRALYMKG
VNPKNYFAPSDGELTLKECLDQWWDKYVTDLKPNTQTLYRSVVYNTMYTQFEGSPVAGIPVSAWARFFDKQESLNKKKAR
VLLLQLRSVINWCISRQLIPSCELLKLSVKNIGKKPDVGSRVLTYTELAKIWLALENSKVVTSNKLLHQLLLLWGARLSE
LRLATASEFNMEDLVWTTPKEHSKMGNIIRRPIFTQVEPYIERLLNAGFDVLFPGQEIDKPIDRSSANLYMKKLREKIDI
PEWRTHDFRRSLVTNLSGEGIMPHVTEKMLGHELGGVMAVYNKHDWLSEQKDAYELYADKIFWHAKQLG
>SEQF1516_EDU84721.1 response regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQHNRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFI
TAWKEHAVEAFELEAFDYILKPYQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEA
HEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYILRLKDLDFEVPVSRSKVKEFRQ
LMHL
>SEQF1516_EDU84722.1 sensor histidine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKELLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFG
PWVGIITGVIAGIHRYLIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWAPTTALG
IDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLPLFRHVNSESLRKVCEIIRDDIHADAVAI
TNTDHVLAYVGVGEHNYQNGDDFISPTTRQAMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQIT
SSLQEMAVGLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNI
ELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNCCIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECG
NRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL
>SEQF1516_EDU84723.1 aminopeptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLSLLKALSEADAIASSEQEVRQILLEEADRLQKEVRFDGLGSVLIRLNESTGPKVMICAHMDEVGFMVRSISREGAID
VLPVGNVRMAARQLQPVRITTREECKIPGLLDGDRQGNDVSAMRVDIGARSYDEVMQAGIRPGDRVTFDTTFQVLPHQRV
MGKAFDDRLGCYLLVTLLRELHSAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAIVLDTACWAKNFNYGAANHRQIG
NGPMLVLSDKSLIAPPKLTAWIETVAAEIGVPLQADMFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDIL
QMEQLLSALIQRLTRETVVQLTDFR
>SEQF1516_EDU84724.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYALIDNASLTAVERTLGDILVKNPDTINGDLVAFENLIQAILFYDTLICVDNYKKEYRDKRIAKFDFIKFVSESDFQL
SELDQLAQVESRQITSEIRGGEFVDDDFRQLVEMLKLNMICTWDLRSSVYYLTMKMLGQPGTPEYAKYSELSASIFNELS
DASDTKGYWSTDVKLVSSSGHEYTEREFELEREKSTRGKGGMTRSLEMFIASLNWLAYKSIYYSVIAKHFKADSFIHPIR
HAYQLHWMKKTGAFGHDYTARLVQSLSDKISTARSEIVDHGRTSTISLDLPIFSAWLANETGNVSQVINSALELRTHDHF
RTCRDVIREIHVTYDESGISAGNKKVTKLLSDLDKISGDIKRSYGVPSNQGIQGSFLIKCINSLTGLVGIPGLPDKEFAL
STPEFMKSKQHKAFSTVFKDVTNELTSIERLGGLRDKLASNFTIDDSYYTEPKTEDPRFRYVSSNWKQPM
>SEQF1516_EDU84725.1 aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMGNPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLR
RAISRWYQDRYDVEIDPESEAIVTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
LERAILESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVYDGWKAPSIMQVPGARDVAVEFF
TLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYGTFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWM
VEMPKASMYVWAKIPEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKAMFRADGLL
PASSKHIHENAE
>SEQF1516_EDU84726.1 drug resistance MFS transporter, membrane fusion protein (MFP) subunit EmrK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQINSNKKHSNRRKYFSLLVIVLFIAFSGAYAYWSMELEDMISTDDAYVTGNADPISAQVSGSVTVVNHKDTNYVRQGD
ILVSLDKTDATIALNKAKNNLANIVRQTNKLYLQDKQYSAEVASARIQYQQSLEDYNRRVPLAKQGVISKETLEHTKDTL
ISSKAALNAAIQAYKANKALVMNTPLNRQPQVVEAADATKEAWLALKRTDIKSPVTGYIAQRSVQVGETVSPGQSLMAVV
PARQMWVNANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGNAFSLLPAQNATGNWIKIVQRVPVEVSLDP
KELMEHPLRIGLSMTATIDTKNEDIAEMPELASTVTSMPAYTSKALVIDTSPIEKEISNIISHNGQL
>SEQF1516_EDU84727.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSLCIDFPRLDIVLRGEYGNLLEAKQQRLVEGEMLFIPA
RAANLPVNNKPVMLLSLVFAPTWLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSL
LHLCRNVVNMPPGNSQPRGDFLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLFAQHGTMRFIEYVRWVRMAKARM
ILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTPGEYSARFQG
>SEQF1516_EDU84728.1 sensor histidine kinase/response regulator EvgS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFLPYIFLLCCGLWSTISFADEDYIEYRGISSNNRVTLDPLRLSNKELRWLASKKNLVIAVHKSQTATLLHTDSQQRVR
GINADYLNLLKRALNIKLTLREYADHQKAMDALEEGEVDIVLSHLVASPPLNDDIAATKPLIITFPALVTTLHDSMRPLT
SSKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGQNDYFIGSNIITSSMISRYFTHSLNVVKYYNSPRQY
NFFLTRKESVILNEVLNRFVDALTNEVRYEVSQNWLDTGNLAFLNKPLELTEHEKQWIKQHPDLKVLENPYSPPYSMTDE
NGSVRGVMGDILNIITLQTGLNFSPITVSHNIHAGTQLNPGGWDILPGAIYSEDRENNVLFAEAFITTPYVFVMQKAPDS
EQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIKVDNASAAFHKVKEGELDALVATQLNSRYMIDHYYPNELYHFLIPGVP
NASLSFAFPRGEPELKDIINKALNAIPPSEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRS
VRRRKVIQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENSESPFKDVFSNTHEVTA
ETKENRTIYTQVFEIDNGIEKRCINHWHTLCNLPASEHAVYICGWQDITETRDLIHALEVERNKAINATVAKSQFLATMS
HEIRTPISSIMGFLELLSGSGLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHSFG
AIAASKSIALSCSSTFPDHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLVHIDDNHAVIKMTIMDSGSGLSQEE
QQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNMQGDLSLESHPGIGTTFTITIPVEIIQQVAAVEAKAEQPITLPEKLS
ILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNVDGFELTRKLREQNSSLPIWGLTANA
QANEREKGLNCGMNLCLFKPLTLDVLKTHLSQLHQVAHIVPQYRHLDIEALKNNTANDLQLMQEILMTFQHETHKDLPAA
FHALEAGDNRTFHQCIHRIHGAANILNLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEIAVFCQQNN
>SEQF1516_EDU84729.1 multidrug resistance protein Y [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAITKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQRI
GELRLFLLSVTFFSLSSLMCSLSINLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPI
LGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIII
LTVVSVIFLISLVIWESTSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPIGIM
PLLISPLIGRYGNKIDMRVLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQGFAVACFFLPLTTISFSGLPDNKFA
NASSMSNFFRTLSGSVGTSLTMTLWGRRESLHHSQLTETIDQFNPVFNSSSQIMDKYYGSLSGVLNEINNEITQQSLSIS
ANEIFRMAAIAFILLTVLVWFAKPPFTAKGVG
>SEQF1516_EDU84730.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIAASYTMHLYCDCLQCTDGKYKSPDFGEYIGTSWAGCAKEARKDGWRISKDKTRAFAPGHKILRSNKGE
>SEQF1516_EDU84731.1 chloride transporter, chloride channel (ClC) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWQRLPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGH
AGPDPACEPLIGAPVPPSALPGLIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALF
GTPVAAALIFSQTLNGSSEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQMEMTDILSGAIVAAIAIAAGMVA
VWCLPRLHAMMHQMKNPVLVLGIGGFILGILGVIGGPVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGF
RGGRIFPAVFVGVALGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVMLPAWLLLAG
KPMMMVNRPKQQPPHDNV
>SEQF1516_EDU84732.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEWAQHQSEPHVHAIIMVNERSINGQAGKIVSKWVTLANNAIPSNVPPQWDLDLKGQQYSEPTKCIGKQIDYMAKPETKL
NDFNREASKSLYDWSDANVWGYSNGWARHEIKKETLSITGFHAVRRILKAVQASRKDNYKAKRQIQRTLKRQDINRSPIT
PFQAPLISKHDWDLSVIAVTKEAETERRELLSSQIINSNKVQTHPLLRMLRRARVRASRAKRESGGYDHYY
>SEQF1516_EDU84733.1 hypothetical protein ECH7EC4501_4965 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNESDIASLDTRVQSLESQVSDHETRINALEYATTRKKSEVVYSGVSVTIPTAPTNLVSLLKTLTPSSGTLAPFFDTVNN
KMVVFNENKTLFFKLSIVGTWPSGTANRSMQLTFSGSVPDTLVSSRNSATTTDNILLATFFSVDKDGFLATNGSTLTIQS
NGAAFTATTIKIIAEQ
>SEQF1516_EDU84734.1 fructokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGIARLGGTSGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWH
RTSTVLVDLNDQGERSFTFMVRPSADLFLETTDLPCWRHGEWLHLCSIALSAEPSRTSAFTAMTEIRHAGGFVSFDPNIR
EDLWQDEHLLRLCLRQALQLADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLVTKGAEGVVVCYRGQVHHFAGMS
VDCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRIIDLAQRCGALAVTAKGAMTALPCRQELE
>SEQF1516_EDU84735.1 hypothetical protein ECH7EC4501_4989 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSFRRNRNYAERCKVKYFFMGISFMVIVWAGTFALMI
>SEQF1516_EDU84736.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEINLMTEKEVSELLQKRRTALYNLRKKHGFPDPVLTHPARYSRQAVEQWLKAGGINRAV
>SEQF1516_EDU84737.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPQQENALRSIARQANSEIKKARQQFPDKNVDDICRSVLKKHRETVTLMGFTPTHLSLAIGMLNGVFKER
>SEQF1516_EDU84738.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKPHYGTALVSREDVKPGTAILYNGRYYMASANVNNALYAHSLIEKIRIISDAIEVYLNNKGQPLISPA
>SEQF1516_EDU84739.1 phage DNA transfer protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLVLSESFKNKLLPMNGYMKGGSDSGSKAQARATEKGIELQREMWQTNMQNLAPFTPLAQQYVSQLQNLSSLQGQGQALN
QYYNSQQYKDLAGQARYQSLAAAEATGGLGSTATGNQLAAIAPTLGQNWLSGQMNNYNNLANIGLGALTGQANAGQNYAN
NVSQLYQQQAAASAANANKPSGLQSFATGAIGGAASGAMIGSAVPVIGTGIGALAGGVIGGLGSLF
>SEQF1516_EDU84740.1 putative prophage DNA injection protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATWQQGINSGGFLAGIGGQNSNAPKASDVSEALAYIRQNNEMERSGRNNIGLQALQGLGSVAQTSQAAKQQEADAAFQK
EYAAAIQSGDRQQVRDLMTKYPGQLEKIQSGMKWADEDQRNSIGTLAAGARLAASSPEAMQSWLQNNAKELARVGVDPNN
VAQMYQQNPSGFGEFVYHLGMAALGPIDYFNVQDKMAGREIDRGRLAETIRSNQAGDFEFKSKPSYLVLSFAEISSVVFI
LMSVYMVAKSQNSNGLQYDALFIPSMAFSILVFSFNGGIISKIISNKVMILLGDASFSFYLVHTIVISTLSKFFNVSGLG
AISVIKFIVMALFASLFISIMMYLFFEKPINNKLRKWWSGFKNDVSTTRVEKIEGNQL
>SEQF1516_EDU84741.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAYLTCDRIEERRWINQQIQDEKDKWIDDRAQELISMFPDKPLLMSSLFLPKEAQLALTGEKAEEAYNDYISAIAYARA
EEEWERKFSPCPF
>SEQF1516_EDU84742.1 resolvase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVRIYCRASTEGQHADRALTSLREFSKSKGWQIAGEYIENASGAKLERVELMRLLSEAQSGDLLLVEAIDRLSRLEHSA
WVELKDTLNRKGLIIVSMDLPTSWQMVEMAGNDLTSGILRAVNAMLIDILATMARQDYETRRKRQQQGIERAKSEGIYIG
RAKNQEAREIVREMLEQGVKPELIMKAAGISRATYYRIKNELLIVKSE
>SEQF1516_EDU84743.1 RecT protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDIVEFVKQQERFFCEALTEPTLTWAKESQFAIQQFQKNDFLAKTAQANLPSAQNAIINVAAIGITLNPSSKLAYLVPR
GGAVCLDISYMGLLHLAQVTGAIQWGQCKLVYEKDIYESNGIDCAPTHKYNPFVDRGARIGGYCVVKTSEGDYLTEEMSN
REIEVIRACSKAGNNGGSSPWDSFPDEMARKAIVKRASKYWPRRDRLDTAIDYLNTQGGEGIILNADHIPERDVTPASDE
IINEITQAITEINKTWDDLLPLCSKTFRRTIASHEYLSQEEAVKTLDFVKKKAARNKATAEAKIHATTENNSEAVS
>SEQF1516_EDU84744.1 integrase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTVKQIEAAKPKEKPYRLLDGNGLYLYVPVSGKKVWQLRYKIDGKEKILTVGKYPLMTLQEARDKAWTARKDISVGIDP
VKAKKASSNNNSFSAIYKEWYEHKRQVWSAAYATELAKMFDDDILPIIGGLEIQDIEPMQLLEVIRRFEDRGAMERANKA
RRRCGEVFRYAIVTGRAKYNPAPDLAEAMKGYRKKNFPFLPADQIPAFNKALATFSGSIVSLIATKVLRYTALRTKELRS
MQWKNVDFENRIITIEASVMKGRKIHVVPMSDQVVELLTTLSSITKPVSEFVFAGRNDKKKSICENAVLLVIKQIGYEGL
ESGHGFRHEFSTIMNEHEWPADAIEVQLAHANGGSVRGIYNHAQYLDKRREMMQWWADWLDGKVE
>SEQF1516_EDU84745.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTLFRKEYPRKSRATEFLFLILFIVLMTPISPLIFVWAIGKIIELVIELYNDVVWASFNTLHNKINPYKEN
>SEQF1516_EDU84746.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKDLKELREYLLLSPVYSEINDCLASLSMEDVTNEEFAERLGIAPDWMDAIDTSQLA
>SEQF1516_EDU84747.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRSLFLAAALMAFTPLAANAGEITLLPSIKLQIGDRDHYGNYWDGGHWRDRDYWHRNYEWRKNRWWRHDNGYHRGWDKR
KAYERGYREGWRDRDDHRGKGRGHGHRH
>SEQF1516_EDU84748.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFYLWMFLALCIVCVSGYIGQVLNVVSAVSSFFGMVILAALIYYFTMWLTGGNELVTGIFMFLAPACGLMIRFMVGYGRR
>SEQF1516_EDU84749.1 hypothetical protein ECH7EC4501_4975 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPLYPDISPEIIAIAIGSGAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVVALAGTFLLSFII
>SEQF1516_EDU84750.1 putative addiction module antidote protein, family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTTQQFSITLTNEMADMVRARVASGAYASESEVIREGLRALNERDKAMEAWLIHSAAPPLDAIRENLGKGHSISQVRSE
IRARK
>SEQF1516_EDU84751.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAVLTELNKLGKASAESISKGLNIDLNDVIDTLWKLKNQGVVTVKNGIWQAVAREVDKKPNIASVQPVQPVQPVQPVQP
VQPVQPVQPVQHNIIGDLLRKSRKEARRAGRKQKRWEGACKALQELNKYRDLINELSE
>SEQF1516_EDU84752.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQESKTMKNRKAKILLVRRNAPGVWQWVRLSNRRMGLMKYYGMMDCGFCKKPSAEQNRWKNHLRTKGE
>SEQF1516_EDU84753.1 oligosaccharide:H+ symporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALNIPFRNAYYRFASSYSFLFFISWSLWWSLYAIWLKGHLGLTGTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLI
WCMSFILVLTGPFMIYVYEPLLQSNFSVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFF
AGIFFSISPHINFWLVSLFGAVFMMINMCFKDKDHQCVAADAGGVKKEDFIAVFKDRNFWVFVIFIVGTWSFYNIFDQQL
FPVFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAIIPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLH
AIEVPLCVISVFKYSVANFDKRLSSTIFLIGFQIASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLLFGIFFLSK
KREQIVMETPVPSAI
>SEQF1516_EDU84754.1 D-serine ammonia-lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGLTEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESE
LVAIPAMQKRLEKEYQQPISGQLLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLEDDYSKLLSPEFKQFFSQ
YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGVAVEEGRKAAQSDPNCFFIDDEN
SRTLFLGYSVAGQRLKAQFAEQGRIVDADNPLFVYLPCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGL
HDQISVQDIGIDNLTAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMAGPQRVCAS
VSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMEQYLAKGR
>SEQF1516_EDU84755.1 phage regulatory protein, Rha family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATIPVLSQPEITISNGRAVTTSFAVAEYFCKRHDNVLRAIANIECSEKFNALNFEDVTYTDAKGEQRPMYQITKNGFVF
LVMGFTGKKAAAFKEAYIAEFDRMEKQLWEQKQLALSSPAMNINFPLSWFSEHHPYATMNYVDRKVISLDASVLFDMPSP
TMRILNELHSKGYNVDAAVAEFNAFKHLTEEMRRQLLDISRTSEKSSRFGFNVNL
>SEQF1516_EDU84756.1 formyl-coenzyme A transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDVTRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGK
EVMEKLIREADILVENFHPGAIDHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPP
LVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRLDKLGYLEEYPQYPNGTFGDAVP
RGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQNWENTCKAIGKPDWITDPAYSTAHARQPHIFDIFAEIEKYTVTID
KHEAVAYLTQFDIPCAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEHTAAVLQEL
GYSDDEIAAMKQNHAI
>SEQF1516_EDU84757.1 addiction module antidote protein, HigA family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMFTPPHPGEIIADILEDQNIGIRELARALDVAPSTVQRLVSGNATISPEMAVRLAAVLGGTPSSWIRLQTAWSLEKAE
REVDVSHLSTKYRPAEISPHA
>SEQF1516_EDU84758.1 hypothetical protein ECH7EC4501_4954 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLFLRITGYRPSLEKGKTILMYAGCFSKYSLCDSLTLTIR
>SEQF1516_EDU84759.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLQELIDLTPEQEKAWNRLVKAVKDFRAAGGKFYSVLDTLSAYNGEHVASIDNDKGYHTASVYMPSIDAPGLTSWADD
WHGITLKDGVEVDKD
>SEQF1516_EDU84760.1 exonuclease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPEIILQRTGVDITSLDQGDDGWHKLRLGVITASEVHNVIAKPRSGSKWPDTKMSYFHTLLAEVCTGVAPEVNAKSLAW
GKQYEDDARALFEFIADVTVSETPIIFRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFDAIKPAYMAQVQF
SMWVTDKDAWYFANYDPRMKREGLHYVVVERDEKYMASFDEMVPEFIEKMDEALAEIGFVFGEQWR
>SEQF1516_EDU84761.1 lipid A biosynthesis lauroyl acyltransferase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFPQCKFSREFLHPRYWLTWFGLGVLWLWVQLPYPVLCFLGTRIGAMARPFLKRRESIARKNLELCFPQHSAEEREKMIA
ENFRSLGMALVETGMAWFWPDSRVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQL
MEWVQTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGRKGSSFAPFFAVENVATTNGTYVLSRLSGAAMLTVT
MVRKADYSGYRLFITPEMEGYPTDENQAAAYMNKIIEKEIMRAPEQYLWIHRRFKTRPVGESSLYI
>SEQF1516_EDU84762.1 hypothetical protein ECH7EC4501_4972 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFAPHAIEIASFLSSWLSKFGELLTLTFIKIKSLTFINAMNITNVNVNYDIL
>SEQF1516_EDU84763.1 glucokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAVIRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWA
FSIAEMKKNLGFSHLEIINDFTAVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGH
VDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDITERALADSCTDCRRALSLFCVI
MGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASGFRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHI
L
>SEQF1516_EDU84764.1 sugar binding transcriptional regulator, LacI family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLASDVCFCYSARFTANGLGMASLKDVARLAGVSMMTVSRVMHNAESVRPATRDRVLQAIQTLNYVPDLSARKMRAQGR
KPSTLAVLAQDTATTPFSVDILLAIEQTASEFGWNSFLINIFSEDDAARAARQLLAHRPDGIIYTTMGLRHITLPESLYG
ENIVLANCVADDPALPSYIPDDYTAQYESTQHLLAAGYRQPLCFWLPESALATGYRRQGFEQAWRDAGRDLAEVKQFHMA
TGDDHYTDLASLLNDHFKSGKPDFDVLICGNDRAAFVAYQVLLAKGVRIPQDVAVMGFDNLVGVGHLFLPPLTTIQLPHD
IIGREAALHIIEGREGGSVTRIPCPLLIRCST
>SEQF1516_EDU84765.1 hypothetical protein ECH7EC4501_4934 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNQKININVKSVVTPAGTIMGEVFMDDKIIAYFVVLSDEAISVIDTEGNVMFIAEHPEDIALQAAAYFFAKEQEEECNC
PVCQLSRQINLMH
>SEQF1516_EDU84766.1 hypothetical protein ECH7EC4501_4960 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKNPVGKIILSTFYPSWRAAVNDLTRTMTNSESTEGLIFRGFCGLVRMEAN
>SEQF1516_EDU84767.1 PTS system, fructose-like, IIC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIKKRSATVVPGASGAAAAVKNPQASKSSFWGELPQHVMSGISRMVPTLIMGGVILAFSQLIAYSWLKIPAEIGIMDAL
NSGKFSGFDLSLLKFAWLSQSFGGVLFGFAIPMFAAFVANSIGGKLAFPAGFIGGLMSTQPTQLLNFDPSTMQWATSSPV
PSTFIGALIISIVAGYLVKWMNQKIQLPDFLLAFKTTFLLPILSAIFVMLAMYYVITPFGGWINGGIRTVLTAAGEKGAL
MYAMGIAAATAIDLGGPINKAAGFVAFSFTTDHVLPVTARSIAIVIPPIGLGLATIIDRRLTGKRLFNAQLYPQGKTAMF
LAFMGISEGAIPFALESPITAIPSYMVGAIVGSTAAVWLGAVQWFPESAIWAWPLVTNLGVYMAGIALGAVITALMVVFL
RLMMFRKGKLLIDSL
>SEQF1516_EDU84768.1 transporter, auxin efflux carrier family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTFFIGDLLPIIVIMLLGYFSGRRETFSEDQARAFNKLVLNYALPAALFVSITRANREMIFADTRLTLVSLVVIVGCFF
FSWFGCYKFFKRTHAEAAVCALIAGSPTIGFLGFAVLDPIYGDSVSTGLVVAIISIIVNAITIPIGLYLLNPSSGADGKK
NSNLSALISAAKEPVVWAPVLATILVLVGVKIPAAWDPTFNLIAKANSGVAVFAAGLTLAAHKFEFSAEIAYNTFLKLIL
MPLALLLVGMACHLNSEHLQMMVLAGALPPAFSGIIIASRFNVYTRTGTASLAVSVLGFVVTAPLWIYVSRLVS
>SEQF1516_EDU84769.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRLIMATMVTAILASSTVWAADNAPVAAQQQTQQVQQTQKTAAAAERISEQGLYAMRDVQVARLALFHGDPEKAKELTN
EASALLSDDSTEWAKFAKPGKKTNVNDDQYIVINASVGISESYVATPEKEAAIKIANEKMAKGDKKGAMEELRLAGVGVM
ENQYLMPLKQTRNALADAQKLLDKKQYYEANLALKGAEDGIIVDSEALFVN
>SEQF1516_EDU84770.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEIKLIDNPVKLAEFLNNPVNTGNIVDSGDKYYIKPDAVYLGIYEGLVLAGVHEVRNFWHSVVECHAVYDPGFRGEYALQ
GHRLFCKWLLENSPFLNSITMVPDTTKYGRAIIRLLGATRVGHLDDAYMSNGKPVGITLYQLPRSKYEELLNVST
>SEQF1516_EDU84771.1 gamma-glutamyl phosphate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILNANAQDVADARANGLSEAMLDRLALTPARLKGIADDV
RQVCNLADPVGQVIDGGVLDSGLRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVVVIQ
DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVITGGIGVCHIYVDESAEIAEALK
VIVNAKTQRPSTCNTVETLLVNKNIAYSFLPALSKQMAESGVTLHADASALAQLQTGPAKVVAVKAEEYDDEFLSLDLNV
KIVSDLDDAIAHIREHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLHARGPMGLE
ALTTYKWIGIGDYTIRA
>SEQF1516_EDU84772.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPVYIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGL
GPKQRQGDFKSPEGFYSVQRNQLKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVNGRYVVSKPLSHEVVQPQLASNY
TLPEAK
>SEQF1516_EDU84773.1 type VI secretion ATPase, ClpV1 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIQIDLPTLVKRLNLFSRQALEMAASECMSQQAAEITVSHVLIQMLAMPRSDLRVITRQGDIGMEELRQALTVENYTTAR
SADSYPAFSPMLVEWLKEGWLLASAEMQHSELRGGVLLLALLHSPLRYIPPAAARLLTGINRDRLQQDFVQWTQESAESV
VPDADGKGAGTLTDASDTLLARYAKNMTEDARNGRLAPVLCRDHEIDLMIDILCRRRKNNPVVVGEAGVGKSALIEGLAL
RIVAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEKRFKGLMAEVISSPVPVILFIDEAHTLIGAGNQQGGLDISNLLKP
ALARGELKTIAATTWSEYKKYFEKDAALSRRFQLVKVSEPNAAEATIILRGLSAVYERSHGVLIDDDALQAAATLSERYL
SGRQLPDKAIDVLDTACARVAINLSSPPKQISALTTLSHQQEAEIRQLERELRIGLRTDTSRMTEVLVQYDETLTALDEL
EAAWHQQQTLVREIIALRQQLLGVAEDDAAPLPDADTVEDTQPESESESEQDNTGAVPADETDREQPEETAETVSPVQRL
AQLTAELDALHNDRLLVSPHVDKKQIAAVIAEWTGVPLNRLSQNEMSVITDLPKWLGDTIKGQDLAIASLHKHLLTARAD
LRRPGRPLGAFLLAGPSGVGKTETVLQLAELLYGGRQYLTTINMSEFQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKP
YSVVLLDEVEKAHPDVLNLFYQAFDKGEMADGEGRLIDCKNIVFFLTSNLGYQVIVEHADDPETMQEALYPVLADFFKPA
LLARMEVVPYLPLSKETLATIIAGKLARLDNVLRSRFGAEVVIEPEVTDEIMSRVTRAENGARMLESVIDGDMLPPLSLL
LLQKMAANTAIARIRLSAVDGAFTADVEDAQNDESVTKDETVL
>SEQF1516_EDU84774.1 DNA polymerase III, epsilon subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLTGNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFA
EVADEFMDYIRGAELVIHNAAFDIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
LHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGEATIQRLVRQASKLRVVFATDEELAAHEARLDLVQKKGGSCL
WRA
>SEQF1516_EDU84775.1 prophage repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAKKKPLTQEQLEDARRLKAIYEKKKNELGLSQESVADKMGMGQSGVGALFNGINALNAYNAALLAKILNVSVEEFSPS
IAREIYEMYEAVSMQPSLRSEYEYPVFSHVQAGMFSPELRTFTKGDAEKWVSTTKKASGSAFWLEVEGNSMTAPTGSKPS
FPDGMLILVDPEQAVEPGDFCIARLGGDEFTFKKLIRDSGQVFLQPLNPQYPMIPCNESCSVVGKVIASQWPEETFG
>SEQF1516_EDU84776.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKKFEGSVAPRERINISYVPKTDGQTAEVELPLNMLVVGDTGNTQETSSLDERQAVSVNKHNFGAVMAEAAIGLNFTVP
ATLKGSTTDDEMNVALNIKSLDDFSPDSVARQVPEVNKLLELREALTALKGPMGNLPAFRTQLQALLENEESREQLLKEI
GQVSNK
>SEQF1516_EDU84777.1 putative peptide chain release factor H [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLETETGRYSDTLRSALISLDGDNAWALSESWCGTIQWICLSPYRPHHGRKNWFLGIGRFTADEQEQSDAIRYETLRPSG
PGGQHVNKTDSAVRATHLATGISVKVQSERSQHANKRLARLLIAWKLEQQQQENSAVLKSQRRMFHHQIERGNPRRTFTG
MAFIEG
>SEQF1516_EDU84778.1 outer membrane pore protein E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYMSDNDSKDGDQSYIRFGFKGETQINDQLTGYGRWEAE
FAGNKAESDTAQQKTRLAFAGLKYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQNLQSRGTGKRAEAWATGLKYDAN
NIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQFDFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSA
FVDYKINQLDSDNKLNINNDDIVAVGMTYQF
>SEQF1516_EDU84779.1 type VI secretion lipoprotein, VC_A0113 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRKAFLACVLMCVILTGCETAKKISEVIKNPDIQVGSLKEQPSEITVTLLTEPDTNTNAEGESAAVDVQLVYLTDDSKL
QAADYDQIASTPLPDVLGKNYIDHQDFNLLPDTIKTLPPIKLDEKTQFIGVVAYFSDDQATEWKQIETVEGTGHHYRLLV
HVRQSSIEMKKEDE
>SEQF1516_EDU84780.1 protein RhsE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPWLHRETARSFGGAGSTAGYEQVTAYTLTGQLQSRHLNLPQLDCDYDWNDNGQLIRISGPQESREYRYSDTGRLTGVHT
TAANLDIDIPYATDPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYRYDEYGRLTEKTDRIPEGVIRMHDERTHHYHYD
NQHRLVFYTRIQYGEPLVESRYLYDPLGRRTGKRVWRRERDLTGWMSLSRKPEVTWYGWDGDRLTTVQTGTTRIQTVYRP
GSFTPLIRIETENGEREKAQRRSLAEKLQQEGSEDGHGVVFPAELVRMLDRLEEEIRADRVSSESRAWLAQCGLTVEQLE
KQVEPEYTPARTLHLYHCDHRGLPLALISEDGNTAWSAEYDEWGNQLNEENPHHLHQPYRLPGQQHDEESGLYYNRHRYY
DPLQGRYITPDPIGLRGGWNMYQYPLNPIQVIDPMGLDAIENMTSGGLIYAVSGVPGLIVANSITNSAYQFGYDMDAIVG
GAHNGAADAMRYCYLMCRMTKTFGSTIADVIGKNHEAAGDRQGQPAKERIMDLKNNTVGIACGDFSAKCSDACIEKYNIG
QLFGLDGIKADNPIKAKQGSSDASNY
>SEQF1516_EDU84781.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATTRNKVMWQEGMLMRPHHFQQQQRYNDYLDNQRFRAMNDLSWGFTELTLNNELLAQGKIMIDSASGTLPDGTVFSIPD
QDALPDPLHPQNFPDERSRNIYLALPVASDVRNEISDGRRIGRYRLNYADVRDLHSEEGDARTLTLGQLTPRIMSGAEDM
SAYITLPLCRISDRHADGSLTLDDDFIPSCQNIQVSKKLRVYLKEVQGAIGGRASDLANRIGSPAQSGIADVAEFMMLQL
LNRNQTRFTHRARRSQLHPEDFYLDLAELLGELMTFTEPSRLPCPLDVYDHHDLTKTFKTLLPEVKRALHTVLSPRAVNL
PLHLRDGIWQADVHDSELLQSATFVLAVAANMPVDQIQRQFIQQSKISSPEKIRNMVSVQIPGIPLRALMVAPRQLPYHS
GFSYFELDKSGQAWTEMAAAGAVALHVSGSFPDLNMQLWAIRG
>SEQF1516_EDU84782.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVFKTKLIRLQLTAEELDALTADFISYKRDGVLPDIFGRDALYDDSFTWPLIKFERVAHIHLANVNNPFPPQLRQFSRT
NDESHLVYCQGAFDEQAWLLIAILKPEPHKLARDNNQMHKIGKMAEAFRMRF
>SEQF1516_EDU84783.1 Inhibitor of vertebrate lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQGHKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPH
DCGSQRIAVMWSEKSNQMTGLFSTIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK
>SEQF1516_EDU84784.1 glutamate 5-kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQ
SRLIQLWEQLFSIYGIHVGQMLLTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAADVACRAGIDTIIAAGSKPG
VIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAGEITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEG
RDIAHGVSRYNSDALRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR
>SEQF1516_EDU84785.1 ImpA domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSNVLTQTIVTGSDPRGLPEFSAIREEINKASHPSQPELNWKLVESLALAIFKANGVDLHTATYYTLARTRTQGLAGFC
EGAELLAAMVSHDWDKFWPQGGPARTEMLDWFNSRTGNILRQQISFAESDLPLIYRTERALQLICDKLQQVELKRVPRVE
NLLYFMQNTRKRLEPQLKSNTENAAQTTVRTLIYAPETQASSTPEAVVPPLPGLPEMKVEVRSLTENPPQASVIKQGSTV
RGFIAGIACSVAVASALWWWQVYPVQQQLLQVNDTAQGAATVWMASPELENYERRLQQLLDTSPVQPLETGMQMMRVADS
RWPESLQQQQASTQWNEALKTRAQSSPQLRGWLQTRQDLHAFADLVMQREKEGLTLSYIKNVIWQAERGLGQETPVESLL
TQYQDARAQKQNTDALEKQINERLEGVLSRWLLLKNNTIPTIKKALNFNNIHEYKGVLNGEFNLFNTKW
>SEQF1516_EDU84786.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQRITLKDYAMRFGQTKTAKDLGVYQSAINKAIHAGRKIFLTINADGSVYAEEVKPFPSNKKTTA
>SEQF1516_EDU84787.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFEERYFREELDYLRQLSKLLATEKPHLARFLAEKDADPDIERLLEGVAFLTGNLRQKIEDEFPELTHGLIKMLWPNYL
RPVPAMTLIEYTPDMDKSSVPVLIPRNEQFTTNAGEIRVDEVLPSDAKKEEPPPCTFTLCRDIWLLPVRLEQIENRSTTR
NGVINITFSVAPGTDFRTLDLNKLRFWLGNDDNYTRDQLYLWFCEYLQGADLTVGEQHIRLPEFMLKAVGFEPQDAMLPW
PKNVHSGYRILQEYFCYPDAFLFFDLCGCPALPDGLQAEFFTLQLRFSRPLPVDIRLRRDSLRLYCAPAINLFIHHAEAI
TLDNRRADYPLVPSRHYPQHYDVFSVNSVVSQVQDMFRKKDLGRPVSTQAARQWPAFESFSHQMEYSRKREVVYWHHRTK
TSLFHRGFDHTLAFIHADGSYPSDESLLSNEVVSVSLTCTNRELPSQIRSGDITGTTGKNAAVASFRNITRPTQPLWPVI
DGSLHWSLLSAMNLNYLSLLDTDALKQVIANFDRHAIHHPQTARLSQQKLDAIERLETRPVDRLFTGIPVRGLASTLYLH
PEPFVCEGEMYLLGTVLSHFLSLYASVNSFHMLTVVNTESQETWKWTERIGQHPLI
>SEQF1516_EDU84788.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILDRERTTGSLFERMEASSARNRQGGSIHSLRQSIRQNLRNILNTRSGSCRGAPELGIDEPEGAENFRESMSRAIEQCI
ERYEPRISHAEVQAVVSSASSPLDMTFHITAWVTFNETHEVLEFDMAPNGSQHYRVD
>SEQF1516_EDU84789.1 hypothetical protein ECH7EC4501_0457 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLFLYYAVERKVVSKGLRSREMAAAGNFGGSVPERKRSTVLSQPL
>SEQF1516_EDU84790.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANNILHSSTSDSESKNTSTDSTLFNEKFPFQLRQDFASRITEDESDFFKWKKIRELAFVSNHKEWNKYDLLI
>SEQF1516_EDU84791.1 addiction module antitoxin component DinJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVAREKALPFDLREPNQLTIQSIKNSEAGVDVHKAKDADDL
FDKLGV
>SEQF1516_EDU84792.1 glutamine amidotransferase, class II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGKGCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQ
ANRGEVALENTHPFTRELWGRNWTYAHNGQLTGYKSLETGNFRPVGKTDSEKAFCWLLYKLTQRYPRTPGNMAAVFKYIA
SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTTPNDVVTVIATQPLTGNETWQKI
MPGEWRLFCLGERVV
>SEQF1516_EDU84793.1 protein RhsA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGGKPAARQGDMTRKGLDIVQGSAGVLIGAPTGVACSVCPGGITYANPVNPVLGAKVLPGETDLALPGPLPFILSRAYSS
YRTRTPAPVGVFGPGWKAPFDIRLQIRDEGLILNDNGGRSIHFEPLFPGEISYSRSESFWLARGGVAEQHSSQPLSALWQ
VLPEDVRLSPHMYLATNSLQGPWWILNWPERVPGADEVLPPEPPAYRVLTGVVDGFGRTLAFHRAAEGDVAGAVTGVTDG
AGRRFHLVLTTQAQRAEVFRKQRATSLSSPAGPRSASSSLVFPDTLPAGTEYGADNGIRLEAVWLTHDPAYPDELPAAPL
ARYTYTASGELRAVYDRSGTQVRGFAYDAEHAGRMVAHHYAGRPESRYRYDDTGRVTELVNPEGLDYRFEYGQDRVTITD
SLNRREVLYTEGEGGLKRVVKKEHADGSITRSEYDEAGRLKAQTDAAGRRTEYSLHMASGAVTAVTGPDGRTVRYGYNSQ
RQVTSVTYPDGLRSSREYDEKGRLAAETSRSGETTRYSYDDPASELPTGIQDATGSTKQMAWSRYGQLLTFTDCSGYTTR
YEYDRYGQQIAVHREEGISTYSSYNPRGQLVSQKDAQGRETRYEYSAAGDLTAIVAPDGSRSEIQYDAWGKAVSTTQGGL
TRSMGYDAAGRITVLTNENGSQSTFRYDPVDRLTEQRGFDGRTQRYHYDLTGKLTQSEDEGLVTLWHYDASDRITHRTVN
GDPAEQWQYDEHGWLTTLSHTSEGHRVSVHYGYDDKGRLTGERQTVENPETGEMLWEHETGHAYSEQGLATRQEPDGLPP
VEWLTYGSGYLAGMKLGGTPLVEYMRDRLHRETARSFGGEAYELATAWNTSGQLRSRHLNLPQLDRDYDWNDNGQLIRIS
GPQESREYRYSDTGRLTGVHTTAANLDIDIPYATDPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYRYDEYGRLAEKT
DRIPEGVIRMHDERTHHYHYDSQHRLVFHTRIQHGEPQVESRYLYDPLGRRTGKRVWRRERDLTGWMSLSRKPEETWYGW
DGDRLTTVQTQQTRIQTVYQPGSFTPLLRIETENGEQAKARHRSLAEVLQEDTGVTLPAELAVMLGRLERELRQGSVSEE
SQQWLAQCGLTAEQMAAQLEAEYIPERKLHLYHCDHRGLPLALISPEGETAWQGEYDEWGNLLGETSAQHLQQSLRLPGQ
QYDEESGLYYNRNRYYDPLQGRYITQDPIGLEGGWNLYQYPLNPIEHIDPLGLALDLNYYSPSDPIYKGSLNVREFPTGF
TVGGHGSPTSMSDDRIKKGSDLTIKQLASDIRANPKYHEGMPVVLFSCETGKGKNSFAQKLANELDATVIAPDEIIWIWP
DGNYAIMGQTARITIGGKDNGVFELVPDEKQPGDFHKFTPTGSK
>SEQF1516_EDU84794.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFYVDYCFVDLAFDIETDSMTAKNDIINECTPLKERNKTLKEKYKKMKR
>SEQF1516_EDU84795.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNDFKAFATDRNANVMSQEEWEALPALISGFTAGKASSAQVNKVIRQASFIAAALAQFVSDKTQRDVLDNGDLPGFVE
LLGSGFAVEYLSRKNPFGDIKSDGTVKTALQNLGLGEAAKRDVGTGENQIPDMASFASGNGWMKLPNGKILQYGRGAVTP
TLSTQTMRITFSIPFPKKADCAMLTHSGDGGAPLGAGRGFVMTAEGPTLTGFNSAYRTSSTSDTVSMNYSWWAVGE
>SEQF1516_EDU84796.1 type VI secretion-associated protein, VC_A0118 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRLRVFRQTGWFIAGLMTGLPATAAPAEASSMAGVAVAVATTTPPDATATLQAMQSCRRESAALERLDCYDHLLAPLSP
SGFDGALVKAGFVGEAWTRATEQEKRREGNTTELLVTQVPGERPTVVITTPAIGHVPPRPVLMFSCVDNITRMQVALMHP
LDVHDIAVTLNADSRALRSHWFVRENGTLLESSRGLSGIDEIKQLFGAKTLTVDTGADNAAGKLTFNIDGLARAIAPLRD
ACHWAGE
>SEQF1516_EDU84797.1 acyl-coenzyme A dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWSAWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVM
PPMSRTEKEAIDAGTTWWEGDLFQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGTDEQKDHYLPRLARGQEIPCFAL
TSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWNKRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTP
GVEIGRRHFPLNVPFQNGPTLGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALATGAYAHIR
RQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAIVKYHCTHRGQQSIIDAMDITGGKGIMLGQS
NFLARAYQGAPIAITVEGANILTRSMMIFGQGAIRCHPYVLEEMEAAKNNDVNVFDKLLFKHIGHVGSNKVRSFWLGLTR
GLTSSTPTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAVLKRYDDEGRNEADLPL
VHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRHYLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHN
PVGLLEEALVDVIAADPIHQRICKELGKNLPFTRLDELAHNALAKGLIDKDEAAILVKAEESRLRSINVDDFDPEELATK
PVKLPEKVRKVEAA
>SEQF1516_EDU84798.1 type III secretion protein, FHIPEP family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSRSDLLTLLTINFIVVTKGAERISEVSARFTLDAMPGKQMAIDADLNAGLINQAQAQTRRKDVASEADFYGAMDGASK
FVRGDAIAGMMILAINLIGGVCIGIFKYNLSADAAFQQYVLMTIGDGLVAQIPSLLLSTAAAIIVTRVSDNGDIAHDVRH
QLLASPSVLYTATGIMFVLAVVPGMPHLPFLLFSALLGFTGWRMSKQPQAAEAEEKSLETLTRTITETSEQQVSWETIPL
IEPISLSLGYKLVALVDKAQGNPLTQRIRGVRQVISDGNGVLLPEIRIRENFRLKPSQYAIFINGIKADEADIPADKLMA
LPSSETYGEIDGVLGNDPAYGMPVTWIQPAQKAKALNMGYQVIDSASVIATHVNKIVRSYIPDLFNYDDITQLHNRLSSM
APRLAEDLSAALNYSQLLKVYRALLTEGVSLRDIVTIATVLVASSAVTKDHILLAADVRLALRRSITHPFVRKQELTVYT
LNNELENLLTNVVNQAQQGGKVMLDSVPVDPNMLNQFQSTMPQVKEQMKAAGKDPVLLVPPQLRPLLARYARLFAPGLHV
LSYNEVPDELELKIMGALS
>SEQF1516_EDU84799.1 hypothetical protein ECH7EC4501_0461 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITGDEDASFGFNLRFDELVAVVVNVILCVGVVATGKVFLLSIFLLPV
>SEQF1516_EDU84800.1 putative chemotaxis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSHPPKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATS
INTIARDAHMEANLEMEIVPQGLRVLIKDDQNRNMFERGSAQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMAYKNNI
YNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDAKNPQSAGNRRIEIMVLTKSASDTLYQYFGQHGDKVVQP
LVQKLDKQQVLSQRTR
>SEQF1516_EDU84801.1 replication protein P for prophage CP-933H [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIAAQMVNFDREQMRRIANIDNQDMTISVWVFPDTDISDVSRELIAAIKQGYLTVKAAGVWAGGIETPSVETPSEGSK
FFGFDMDNEFISGFDVGAWGVLL
>SEQF1516_EDU84802.1 ribonuclease H [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTNNRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQ
WIHNWKKRGWKTADKKPVKNVDLWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV
>SEQF1516_EDU84803.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVFTFLLIIMVCLYNFGVRAAMDNSKHSDEAEKLLAELSARKGEGEGEGEGEGEGEGEGEGEGEGEPKSTVSVFYLQPE
EVNTLSHQAKRGDGEAGFRLFLYYKLSNYDEEKSSQWLKIAANNGHATAQYRLYVELQEQGETKEANEWLQKIKLAASNN
DSSAIWFLVNCYKNQGNKKEALQWAYKLKASKQPLDADRLIEELTKEQK
>SEQF1516_EDU84804.1 NlpC/P60 family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHDQPLLSMSLPSIPSFVLSGLLLICLPFSSFASATTSHISFSYAARQRMQNRARLLKQYQTHLKKQVSYIVEGNAESRR
ALRQHNREQIKQHPEWFPAPLKASDRRWQALAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDKGFDCSGLVF
YAYNKILEAKLPRTANEMYHYHRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDGQFIESPRTGETIRVSRLAEPFW
QDHFLGARRILTEETIL
>SEQF1516_EDU84805.1 putative transposase, IS4 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIQSLLDYISVIPDIRQQGKVKHKLSDILFLTVCAVIAGADEWQEIEDFGHERLEWLKKYGDFDNGIPVDDTIARVVSN
IDSLAFEKIFIEWMQECHEITDGEIIAIDGKTIRGSFDKGKRKGAIHMVSAFSNENGVVLGQVKTEAKSNEITAIPELLN
LLDLKKNLITIDAMGCQKDIASKIKDKKADYLLAVKGNQGKLHHAFEEKFPVNVFSNYKGDSFSTQEISHGRKETRLHIV
SNVTPEFCDFEFEWKGLKKLCVALSFRQKKEDKSAEGVSIRYYISSKDMDAKEFAHAIRAHWLIEHSLHWVLDVKMNEDA
SRIRRGNAAEIISGIKKMALNLLRDCKDIKGGVKRKRKKVALNTCYIEEVLASCSELGFRTDKMKNLTQI
>SEQF1516_EDU84806.1 aminoacyl-histidine dipeptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKGFHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMV
PQKNNDTVHDFTKDPIQPYIDGEWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGGEIHVGLGNANKLLVRFLAGHAE
ELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDALKSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTF
IRLLNATPNGVIRNSDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEAKGAYPGWQ
PDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIGPTITGPHSPDEQVHIESVGHYWTLLTELLK
EIPAK
>SEQF1516_EDU84807.1 xanthine phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGD
GEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR
>SEQF1516_EDU84808.1 ISEc3, transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELKKLMEHISIIPDYRQAWKVEHKLSDILLLTICAVISGAEGWEDIEDFGETHLDFLRQYGDFENAIPVHDTIARVVSC
ISPAKFHECFINWMRDCHSSDDKDVIAIDGKTLRHSYDKSRRRGAIHVISAFSTMHSLVIGQIKTDEKSNEITAPPELLN
ILDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNPEHDSYAISEKSHGREEIRLHIV
CEVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKEPKMTVRYYISSADLTAGKFATAIRNHWHVENKLHWRLDVVMNED
DCKIRRGNAAELFSGIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVLAGSGLS
>SEQF1516_EDU84809.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDEGSLSLPPFTGYDEKSLRDYHLALHGNSLNPMIDAATPLLGMVMRLSTMNSQTMPEHLFAQVVTDVQAVEQLLQEQGY
EPGVIISFRYILCTFIDEAALGNGWSNKNEWIKQSLLVHFHNEAWGGEKVFILLERLIREPKRYQDLLEFLWLCFSLGFR
GRYKVAVQDQGEFEQIYRRLYHVLHKLRGDAPFPLLHQDKKTQGGRYQLISRLTVKHIFCGGVVVLALFYLFYLLRLDSQ
TQDILHQLNKLLR
>SEQF1516_EDU84810.1 site-specific recombinase, phage integrase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHKHAAANVAQRNRLNGKQIGFWLQHFAGMQLRDITESKIYSAMQKMTNRRHEENWKLRAEACRKKGKPVPEYTPKPASV
ATKATHLSFIKALLRAAEREWKMLDKAPIIKVPQPKNKRLRWLEPHEAQRLIDECPEPLKSVVEFALATGLRRSNIINLE
WQQIDMQRRVAWINPEESKSNRAIGVALNDTACRVLKKQIGNHHRWVFVYKESCTKPDGTKAPTVRKMRYDANTAWKAAL
RRAGIDDFRFHDLRHTWASWLVQAGVPLSVLQEMGGWESIEMVRRYAHLAPNHLTEHARQIDSILNPSVPNLSQSKNKEG
TNDV
>SEQF1516_EDU84811.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNIQIRNYQPGDFQQLCAIFIRAVMMTASQHYSPQQIAAWAQIDESRWKEKLAKSQVRVAVINAQPVGFISRIEHYIDM
LFVDPEYTRRGVASALLKPWIKSESELTVDASITAKPFFERYGFQTVKQQRVECRGAWFTNFSMRYKPQH
>SEQF1516_EDU84812.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTPCYISITGQTQGNITAGAFTADSVGNIYVQGHEDEMLVQEFLHNVTVPTDPQSGQPAGQRAHKPFIFTVALNKAVPL
MYNALASGEMLPTTELHWWRTSVEGKQEHYFTTRLTDSTIVDMKLHMPHCQDPAKREFTQLLEVSLAYRKIEWEHVKSGT
SGADDWRAPLEA
>SEQF1516_EDU84813.1 sigma factor-binding protein Crl [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLREFHEKLRELLTTLNLKLEPADD
FRDEPVKLTA
>SEQF1516_EDU84814.1 hypothetical protein ECH7EC4501_0455 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIQLWPFYGGNTDFEQLGMAIQIYIIKLLLNKRFNDFKNSFYDNRKF
>SEQF1516_EDU84815.1 hypothetical protein ECH7EC4501_0453 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAHKNISGTYHLSVADILQVVYQVCFSPSVEINQDGVAALITTLDRRISDLLDEIIHFCEFQQSASHWQRVLH
>SEQF1516_EDU84816.1 type VI secretion system Vgr family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTGLRFTLEVDGLPPDAFAVVFFHLNQSLSSLFSLALSLVSQQFLSLEFQQILDKMAYLTIWQGDDVQRRVKGVVTWFE
LGENDKNQKLYSMKVCPPLWRTGLRQNFRIFQNEDIASILGTILQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
AAEEGIFFYEEHAQKSTDQSLVLCDTVLYLPESFEIPWNPNTRTEVSTLCISQFRYSAQIRPSSVVTKDYTFKRPGWAGR
FDQEGQHQDYQRTQYEVYDYPGRFKGAHGQNFARWQMDGWRNNAEVARGTSRSPEIWPGRRIVLTGHPQANLNREWQVVA
SELHGEQPQAVPGRRGSGTTLDNHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRVRVKFNWDRYNPS
NQDSSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTYHQENRTPGSLPGTKTQMTIRSKTYKGSGFN
ELKFDDATGKEQVYIHAQKNMNTEVLNNRTTDVINNHAEKIGNNQAITVTNNQILNIGVNQIQTVGVNQVETVGSNQIIK
VGSNQVEKVGIIRALTVGVAYQTTVGGIMNTSVALLQSSQVGLHKSLMVGMGYSVNVGNNVTFSVGKTMKENTGQTAVYS
AGEHLELCCGKARLVLTKDGSIFLNGTHIHLEGESDVNGDAPVINWNCGATQPVPDAPVPKDLPPGMPDMRQF
>SEQF1516_EDU84817.1 hypothetical protein ECH7EC4501_0466 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNGHNEQHQKEKNIKYIQKDMRARDGAGQDHENRDVNHDFHPGFNAYR
>SEQF1516_EDU84818.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSKKLCCICVLFSLLAGCASESSIDEKKKKAQVTQSNINKNTPQQLTDKDLFGNETTLAVSEEDIQAALDGDEFRVPLN
SPVILVQSGNRAPETIMQEEMRKYYTVSTFSGIPDRQKPLTCNKNKDKNENEDVARAENMNWMQALRFVAAKGHQKAIIV
YQDMLQTGKYDSALKSTVWSDYKNEKLTDAISLRYLVRFTLVDVATGEWATWSPVNYESRVIFPPAGITKTSNKELSNDH
VTEAQLFNLKQKTYVSMVKDLVSRFQ
>SEQF1516_EDU84819.1 hypothetical protein ECH7EC4501_0479 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDATLARLIMPTKLHSTVGRIRRSRRIRQLCTNAGCAP
>SEQF1516_EDU84820.1 DNA polymerase IV [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYK
EASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFSELQLTASAGVTPVKFLAKIASDMNKPNG
QFVITPAEVSAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVILLKRFGKFGRILWERSQGIDERDVNSERLR
KSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTW
DERRGGRGVRLVGLHVTLLDPQMERQLVLGL
>SEQF1516_EDU84821.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPEEKLQTLSLQVINGSELESGRAARCLFTQQGNVGHAPECHWSVQDRQQSIPAQAFTVILHDGTFCLRPQTAQLWLNQA
KVTATSDLIQLRQGDEIQIGRLMVRVHLNRGDIPHYDEEMATPETIVTNRDMLTDTLLSTEGAPHYPGMTHRHQLADTVV
NGFSADPLQALQSESLITTGDPLSGIAAVRPSAPLSDPASNGGINTPFMDLPPIYASPGDHNDDISAAEMAQRHLAVTPL
LRGLGGSLTVSNSDDADDFLEEAGRTLQAAIKGLLDLQQQRNSLSDKHLRPLEDNPLRLNMDYATALDVMFAEGKSPVHL
AAPAAVSESLRNVRHHEEANRAAIVESLRVLLDAFSPQNLLRRFVQYRRSHELRQPLDDAGAWQMYSHYYEELASDRQQG
FEMLFNEVYAQVYDRVLREKQREPEA
>SEQF1516_EDU84822.1 hydrolase, carbon-nitrogen family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMFTSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGS
VALQTESGSVNRFLLVEPGGTVHFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAI
YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIATADAHQATRIDAELSMVALREY
REKFPAWRDADEFRLR
>SEQF1516_EDU84823.1 fermentation-respiration switch protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTIPHWYRMINRLMWIWRGIDPREILDVQARIVMSDAER
TDDDLYDTVIGYRGGNWIYEWATQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYFAPRGIAMLTIDMPSVGFSSKWK
LTQDSCLLHQRVLKALPNVPWVDHTRVAAFGFRFGANVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDV
LASRLGMHDASDEALRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFNPVYRNFDK
GLQEITDWIEKRLC
>SEQF1516_EDU84824.1 phosphoheptose isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAGGKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAI
AISDVSHISCVGNDFGFNDIFSRYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK
>SEQF1516_EDU84825.1 addiction module antitoxin, Axe family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHRILAEKSVNITELRKNPAKYFIDQPVAVLSNNRPAGYLLSASAFEALMDMLAEQEEKKPIKARFRPSAARLEEITRRA
EKYLNDMTDDDFNDFKE
>SEQF1516_EDU84826.1 RtcB protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQRVVGMPDLHPGRGYPIGAAFFSVGRFYPTRRRGNGAGNRN
GPLL
>SEQF1516_EDU84827.1 regulatory protein CII [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLAVLEWGVVDDDMARLARQVAAILTNKKRPAATERSEQIQMEF
>SEQF1516_EDU84828.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDGKNRAASSYLSPGNPPADKEQNDPLAQVFHNACSYNFFAMAELLHRLAKGEKGTPELSLRDDPAQETLRFSADASLAF
PCSDISALKRDTSGAFRMTTTFMGLQGSQSPLPGYYLDHLAWKAVHEQSPVGDFLDMFSHRLTQFVWHIWRKYRYHISFR
NGGVDAFSQRMYSLVGLGHRQLRDKLAINHSKMLAYSGILANPGRSPEIICGLVSHCFDLSEVTLQNWQRRKVDIEPDQQ
NSLGSYSLKNGEKLAGRSVLGNFVLGTRVPDLSGKFQLSITSLTRKQFLSFLPSGENFLPLTTFVSFILRDQLAWDLHLG
LAPEQVGAMRLGDNKSALLGWTSFLGTPEERPSVTIRVRS
>SEQF1516_EDU84829.1 putative methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPARVPQTVVAPDRWGDLPWGELYRKALERQLNPWFTKMYGFYLLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQAD
PLHLPFADKSVDVCLLAHTLPWCTDPHRLLREADRVLIDDGWLVISGFNPISLMGLRKLVPVLRKTSPYNSRMFTLMRQL
DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQSKNKPRIRQAVGATRQCRKPQA
>SEQF1516_EDU84830.1 non-LEE encoded type III effector C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIPSLQSNFNFSAPAGYSAPIAPNRAENAYADYVLDIGKRIPLSAADLSNVYESVIRAVHDSRSRLIDQHTVDMIGNTV
LDALSRSQTFRDAVSYGIHNEKVHIGCIKYRNEYELNEESSVKIDDIQSLTCNELYEYDVGQEPIFPICEAGENDNEEPY
VSFSVAPDTDSYEMPSWQEGLIHEIIHHVTGSSDPSGDSNIELGPTEILARRVAQELGWSVPDFKGYAEPEREAHLRLRN
LNALRQAAMRHEENERAFFERLGTISDRYEASPDFTEYSAVSNIGYGFIQQHDFPGLAINDNLQDANQIQLYHGAPYIFT
FGDVDKHNQQ
>SEQF1516_EDU84831.1 prophage minor tail protein Z [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKGLENAIRNLNSLDTRMVPQASAWAINRVAQKAGSVATRQVAGNTVAGDNQVKGIPLKLVRQRVRVFKASPSGKMTARI
RVNRGNLPAIKLGTARVRLAQRGGKLQYRGSVLKVGKYLFRDAFIQQLANGRWHVMRRIDGKNRYPIDVVKIPLSGPLTQ
AFEDARDRIIAAEMPKQLGYALKQQLRLWLTR
>SEQF1516_EDU84832.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPSMIAIILLIILHIWLCRQGGAHFWSESWLNISLLMLDIEHLARGKGLR
>SEQF1516_EDU84833.1 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKLLKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLP
VEKSWKLNERHYGALQGLNKAETAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDR
VIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEFDENFKPLKRYYLGNADEIAAKA
AAVANQGKAK
>SEQF1516_EDU84834.1 recombination protein bet [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNESCTCRIYRKDRNHPICVTEWMDEC
RREPFKTREGREITGPWQSHPKRMLRHKAMIQCARLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEIN
TLLIALDKTWDDDLLPLCSQIFRRDIRASSELTQAEAVKALGFLKQKATEQKVAA
>SEQF1516_EDU84835.1 UDP-glucose 4-epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHPTFVEGDIRNEALMTEILHDHAIDTVIHF
AGLKAVGESVQKPLEYYDNNVNGTLRLISAMRAANVKNFIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQIL
TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIFGNDYPTEDGTGVRDYIHVMDLA
DGHVVAMEKLANKPGVHIYNLGAGVGSSVLDVVNAFSKACGKPVNYHFAPRREGDLPAYWADASKADRELNWRVTRTLDE
MAQDTWHWQSRHPQGYPD
>SEQF1516_EDU84836.1 adenosylmethionine-8-amino-7-oxononanoate transaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSVGGEPWGFSKTCFLLLIRCRLVNLNLFNLVYKSIMTTDDLAFDQRHIWHPYTSMTSPLPVYPVASAEGCELILSDGR
RLVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQPLECVFLADSGSVAVEVAMKMA
LQYWQAKGEARQHFLTFRNGYHGDTFGAMSVCDPDNSMHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRH
EIAAVIIEPIVQGAGGMRMYHPEWLKRIRKMCDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKALTGGTMTL
SATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQQQVAAIEVQLREQLAPARDAEMVADVRVLG
AIGVVETTRPVNMAALQKFFVEQGVWIRPFGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ
>SEQF1516_EDU84837.1 tail assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQTESAILAHARRCAPAESCGFVVSTPEGERYFPCVNISGEPEAYFRMSPEDWLQAEMQGEIVALVHSHPGGLPWLSEA
DRRLQVQSDLPWWLVCRGTIHKFRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHREDDWWRHGQNLYLDNLEAT
GLYQVPLSSAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRRTHSLWRHRAWRASAFTGICNDL
AAASTFV
>SEQF1516_EDU84838.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFYKLCLLAVVILLLVMVMMDFTSRIMLVLTDGALVCGIVVLLWPMMKEQNE
>SEQF1516_EDU84839.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDHELKNLVLNINQLAALSGLHRQTVVARLKNIRPAGGHDKLKLYRLTDILTEFMGLPPPVAEGEMDPHERKAWYQSERE
RLKFEQETAQLIPASDVRREFAIWAKAVVQVLETLPDILERDCGLQPAAVSRVQSIIDDLRDQIALRVTEAGADDEEELQ
QEE
>SEQF1516_EDU84840.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSSCIGVVMKDGALLRSSSLFIAYMGCLGWGSAYFYGWGTSFYYGFPWWIVGAGVDDVARSLFFAVIVIAIFLIGWGIG
VVFFFAVKRKHSMQELNVFRLYFAVELLFVPAIIEFSILRQKIQVPLLLLSAAIALAVTISIRSYGRFLSVSCFYDKPFI
KKHFFEIVMIAFVAYFWLFSFLTGYYKPQFKKEYEMINYNDGWYYVLARYDNCLVLSTSFNAGSKRFVIYQSAQDKNLQV
DIVRTRI
>SEQF1516_EDU84841.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYFLRKKWMVNLSGAGKILWALNMKKDSYPYLICMTVLGLIFIFFFFWWRADIYRVTFLNQSISHYYILFSMGIAFLLS
LFWVKKGIVKQSGWKSLSAYLKVYAGMCIFAGFFLIIPLTTLTYFLPGETSSYVAPYRYTSGSSKSCSGAEVDDPDLHEN
IRICYPYGNYEYDNIIYVEKKINTLGAVVTYAQTARDDTE
>SEQF1516_EDU84842.1 phage lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSPSLRKAVAAAIGGGAAAIASVLITGPSGDDGLEGVSYIPYEDIVGVWTVCHGHTGKDIIPGKTYTEAECKALLNKDLA
TVARQINPYIKVDIPETTRGALYSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREVC
LWGQQ
>SEQF1516_EDU84843.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEEDLHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDET
LFNIRDMNAYHRGMVTLACIPTAVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFT
PLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLDWFYEVRHLSTSLGLVEAGLGIS
ALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKDAVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG
>SEQF1516_EDU84844.1 molybdate ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGKALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERL
YDWFGITFAFSWRGAVLAAAVMSFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEWLARISRERAGR
>SEQF1516_EDU84845.1 anion transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIVGLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTA
VLSGYSSGTTWLVFSAFTLSAAFVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSV
AVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISWGGWALAAGLPGIIMLLVTPLVI
YTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLGVFVLALLGWIFSKSLGVDESSVAIVVMATMLLLGIVTWEDVVKN
KGGWNTLIWYGGIIGLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAMLPVFAMLAN
VSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGAVLTILTFLVHITLGVWWWNML
>SEQF1516_EDU84846.1 galactokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVLPCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSL
DAPIVAHENYQWANYVRGVVKHLQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQE
AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTLVGSEYNTRREQCETGARFFQQP
ALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTVEAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVK
AVIGDKGGVRMTGGGFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC
>SEQF1516_EDU84847.1 NleB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSPIRTTFHNSVNIVQSSPCQTVSFAGKEYELKVIDEKTPILFQWFEPNPERYKKDEVPIVNTKQHPYLDNVTNAARIE
SDRMIGIFVDGDFSVNQKTAFSKLERDFENVMIIYREDVDFSMYDRKLSDIYHDIICEQRLRTEDKRDEYLLNLLEKELR
EISKAQDSLISMYAKKRNHAWFDFFRNLALLKAGEIFRCTYNTKNHGISFGEGCIYLDMDMILTGKLGTIYAPDGISMHV
DRRNDSVNIENSAIIVNRSNHPALLEGLSFMHSKVDAHPYYDGLGKGVKKYFNFTPLHNYNHFCDFIEFNHPNIIMNTSQ
YTCSSW
>SEQF1516_EDU84848.1 quinolinate synthetase complex, A subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVMVAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTL
LVAGVRFMGETAKILSPEKTILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELI
DHLDSLGEKIIWAPDKHLGRYVQKKTGADILCWQGACIVHDEFKTQALTRLQEEYPDAAILVHPESPQAIVDMADAVGST
SQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPDKELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEGSNYEVHV
DERLRERALVPLNRMLDFAATLRG
>SEQF1516_EDU84849.1 transcriptional regulator ModE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGISYKSAWDAINEMNQLSEHILVERATGGKGGGGAVLTR
YGQRLIQLYDLLAQIQQKAFDVLSDDDALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKTRLKV
AITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGIISHIERGAEQCEVLMALPDGQTLCATVPVNEATS
LQQGQNVTAYFNADSVIIATLC
>SEQF1516_EDU84850.1 phage tail assembly protein T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLAREFRRADWRRMLSEMSATELGEWGDYFRMQSFSDVWMDAQFASLKALIVRMVSGSSDAAVADFSLLPEENGIPERT
DEELMHLGEGISGGVRYGPDSQPGH
>SEQF1516_EDU84851.1 phage minor tail protein G [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLKQGTFNYEKQSVVLSELSGLQRIEYLAFVQQRTAKFDAEEGELPEAERQIAFLRMGMDINAWLVSRSLWNAEQSQDV
ETLCASVITTWSYDALGAGAEMVLSLSGMGAIENAGDLEHEVLTPEKS
>SEQF1516_EDU84852.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPQQENALRSIARQANSEIKKARQPFPDKNVDDICRSVLKKHRETVTLMGFTPTHLSLAIGMLNGVFKER
>SEQF1516_EDU84853.1 phage minor tail protein U [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRHTQIRQVVLARLREQCGDSATFFDGLPAFVDAQELPAVAVWLSDAQYTGKMTDEDDWQAVLHIAVFIRAQAPDSELD
MWMESTIFPALNDVSALSGLIDTLIPLGFNYQRDNEMATWAMAEITYQITYTN
>SEQF1516_EDU84854.1 molybdate ABC transporter, periplasmic molybdate-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDIATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFI
SADQKWMDYAVDKKAIDTATRQTLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKL
GAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKVEYPVAVVEGHNNATVKAFYDYL
KGPQAAEIFKRYGFTTK
>SEQF1516_EDU84855.1 galactose mutarotase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNETPALAPDGQPYRLLTLRNNAGMVVTLMDWGATLLSARIPLSDGSVREALLGCASPECYQDQAAFLGASIGRYANRI
ANSRYTFDGETVTLSPSQGVNQLHGGPEGFDKRRWQIVNQNDRQVLFALSSDDGDQGFPGNLGATVQYRLTDDNRISITY
RATVDKPCPVNMTNHVYFNLDGKQSDVRNHKLQILADEYLPVDEGGIPHDGLKSVAGTSFDFRSAKIIASEFLADDDQRK
VKGYDHAFLLQAKGDGKKVAAHVWSADEKLQLKVYTTAPALQFYSGNYLGGTPSRGTEPYADWQGLALESEFLPDSPNHP
EWPQPDCFLHPGEEYSSLTEYQFIAE
>SEQF1516_EDU84856.1 hypothetical protein ECH7EC4501_1614 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFFQFFNSNIGYVCMCYLRPYHPVVIAVIDVLCFDNSVEWFSIPFTCDSEVHLSSP
>SEQF1516_EDU84857.1 molybdate ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAISGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGY
VFQDARLFPHYKVRGNLRYGMAKSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLD
IPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWGSSVMNPWLPKEQQSSILKVTVL
EHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKT
LWARISPWARDELAIKPGLWLYAQIKSVSITA
>SEQF1516_EDU84858.1 exonuclease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAW
GKQYENDARTLFEFTSGVNVTESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQY
SMWVTRKDAWYFANYDPRMKREGLHYVVVERDEKYMAGFDEMVPEFIEKMDEALAEIGFVFGEQWR
>SEQF1516_EDU84859.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRVTAIISALVICIIVCQSWAVNHYRDNAIAYKEQRDKKVSELKQATATITDMQQRQRAADALDAKYTKELADAKAKND
ALRRKLDNGGRVFVKGKCPVPSSDETSSASGMGNDATVELSPVAGRNVLGIRDGIIRDQTALRTLQEYIRTQCLR
>SEQF1516_EDU84860.1 enterobacterial Ail/Lom family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKVCAAILSAAICLAVSGVPAWASEHQSTLSAGYLHASTDAPGSDDLNGINVKYRYEFTDTLGLITSFSYANAEDEQKT
HYSDTRWHEDYVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRVSTFSGDYFRVTDNKRKTHDVLTGSDDARYSNTSLAW
GAGVQFNPTESVAVDVAYEGSGSGDWRTDGFIVGVGYKF
>SEQF1516_EDU84861.1 pectinesterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPILSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQP
DFVVGPAGTQGVTHTTIQAAVDAAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPA
DWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENTLGDSVDAGNHPAVALRTDGDQV
QINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVTNSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLS
NIYYGFLAVNSRFNASGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWGDAVISNRPFAGNTGSVDDSDEIQRN
LNDTNYNRMWEYNNRGVGSKVVAEAKK
>SEQF1516_EDU84862.1 phosphatase YbhA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVNAELKRRILSDSGIGVPFAQKKILNLNLEYAMTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTGRH
HVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHIHGLMYVDDEMVYEHPTGHVIRTSN
WAQTLPPEQRPTFTQVASLAETAQQVNAVWKFALTHDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTK
WVEAQGWSMENVVAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI
>SEQF1516_EDU84863.1 6-phosphogluconolactonase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVSPDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESAL
PGSPTHISTDHQGQFVFVGSYNAGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDG
HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTLDMMPENFSDTRWAADIHITPDG
RHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQPRGFNIDHRGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVG
QGPMWVVVNAH
>SEQF1516_EDU84864.1 3-deoxy-7-phosphoheptulonate synthase, Phe-sensitive [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNYQNDDLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIHKILKGNDDRLLVVIGPCSIHDPVAAKEYATRLLALR
EELKDELEIVMRVYFEKPRTTVGWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLMSWG
AIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHSAIVNTSGNGDCHIILRGGKEPN
YSAKHVAEVKEGLNKAGLPAQVMIDFSHANSSKQFKKQMDVCADVCQQIAGGEKAIIGVMVESHLVEGNQSLESGEPLAY
GKSITDACIGWEDTDALLRQLANAVKARRG
>SEQF1516_EDU84865.1 putative outer membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKSVIAGVFIALSFTTCSAIANSLALSLANDDAGKFQPILNDIYGNKHENRDDYSQGLFLGYSHDISDSSQLSLHIAQD
IYSPSGSNKRHNTAVTGDRAFSAYTHTGIEWNSLANDWIRYRLGTDIGVVGPDAGGQKVQNKAHEIIGAEKYHAWDDQIE
NRYGYTVKGMLSMTPSMDILGANVGLYPEVSAVTGNLFQYVAYGATIAIGNDKTFNSDNGFGLLAPRGLMHMSDTSGFKY
KIFAGMERRDVNRNYTLEGKTIQTKQTTVSLNKTVDEYQVGATIGYAPVAFTLAFNKVTSEFKTGDDYSFINGAITFFF
>SEQF1516_EDU84866.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKMTKLATLFLTATLSLASGAALAADSGAQTNNGQANAAADAGQVAPDARENVAPNNVDNNGVNTGSGGTMLHPDGSSMN
NDGMTKDEEHKNTMCKDGRCPDINKKVQTGDGINNDVDTKTDGTTQ
>SEQF1516_EDU84867.1 putative prophage tail fibre C-terminus family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNILRKLMQSLCGCGKHDDCENGRSLTAQLRLGPADILESDENGIIPEQDRVITQVVILDADKKQIQCVVRPLQILRADG
TWENIGGMK
>SEQF1516_EDU84868.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPGQNH
>SEQF1516_EDU84869.1 gifsy-1 prophage VmtV [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTPNPLAKTKGAGTTFWMYTGNGDAFANPLSDTDWLRLAMVKDLQPGEMTADAEDDTYLDDEDADWKTTTQGQKSVGDT
SATLAWRPGDSGQKKLVQLFDSGEVCAFRIKYPNGTVDVFRGWLSSLGKTIASKDVMTRTVKISGVGRPYLAEEGTETVG
VTGLTVAPASASVNVGATTTLTFTVKPDGASDKAISVHSTDPQTATVTLNGLVATVKGVKQGSVSIVGMTADGNFVAVAA
VTVSAAG
>SEQF1516_EDU84870.1 hypothetical protein ECH7EC4501_1608 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPSYLIIHASLLLREMEATILGGWPLKILTAFSQLKLMKKCY
>SEQF1516_EDU84871.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGYKMSSLQILQGTFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSALARALAGELPLLKGERQSQFSHITRLSFEQLQ
KLVSDEWQRNNTDMLGPGEDDTGRTTAEIIQDEVKDAPRCMQLAQQFGITPLLDRRFKYLSTGETRKTLLCQALMSEPDL
LILDEPFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGAKEELLQQALVAQLAHSEQ
LEGVQLPEPDEPSARHALPANEPRIVLNNGVVSYNDRPILNNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSN
DLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDKRTAD
APFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISEGETQLLFVSHHAEDAPACITHRLEFV
PDGGLYHYALTKIN
>SEQF1516_EDU84872.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPIPVETDEEFHTLATSLSQKLEMMVAKAEADERDLV
>SEQF1516_EDU84873.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGNDLEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQV
IVHEKRVDTTPNCGNMLSGVGAFAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVA
LTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELDADKALLARIESIRLQAGKAMGL
GDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRALAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGGLDVH
LSNEGQDATTLRASVIRTTRKIFSGEVYLP
>SEQF1516_EDU84874.1 phage minor tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METFHWKVRPDMNVVSEPKVVTVKLGDGYEQRRAAGLNNQLSTYSVTIRVRKCEHPSLKAFLERHGGVRAFQWTPPYDWK
PIRVVCRKWSASVGALWVTITADFEQVVA
>SEQF1516_EDU84875.1 non-LEE-encoded type III effector H [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSPYSVNLGCSWNSLTRNLTSPDNRVLSSVRDAAVHSDNGAQVKVGNRTYRVVATDNKFCVTRESHSGCFTNLLHRLGW
PKGEISRKIEVMLNASPVSAAMERGIVHSNRPDLPPVDYAPPELPSVDYNRLSVPGNVIGKGGNAVVYEDAEDATKVLKM
FTTSQSNEEVTSEVRCFNQYYGAGSAEKIYGNNGDIIGIRMDKINGESLLNISSLPAQAEHAIYDMFDRLEQKGILFVDT
TETNVLYDRAKNEFNPIDISSYNVSDRSWSESQIMQSYHGGKQDLISVVLSKI
>SEQF1516_EDU84876.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQNDIEAMIQRYTEAEMAVLDGKSVTFNGQQMTMENLSEIRQGRQEWERRLAALITRRRGHPGYRLARF
>SEQF1516_EDU84877.1 galactose-1-phosphate uridylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQFNPVDHPHRRYNQLTGQWILVSPHRAKRPWQGAQETPAKQVLPAHDPDCFLCAGNVRVTGDKNPDYTGTYVFTNDFA
ALMSDTPDAPESNDPLMRCQSARGTSRVICFSPDHSKTLPELSVAALTEIVKTWQEQTAELGKTYPWVQVFENKGAAMGC
SNPHPHGQIWANSFLPNEAEREDRLQKEYFAEQKSPMLVDYVQRELADGSRTVVETEHWLAVVPYWAAWPFETLLLPKAH
VLRITDLTDAQRSDLALALKKLTSRYDNLFQCSFPYSMGWHGAPFNGEENQHWQLHAHFYPPLLRSATVRKFMVGYEMLA
ETQRDLTAEQAAERLRAVSDIHFRESGV
>SEQF1516_EDU84878.1 bacteriophage lambda tail assembly protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQIPAFRQKLSDGWYLVRIAGRDTGENELSARLNEPLANGAVIHIVPRLAGAKSGGVFQAVLGAALIAVAWWNPVGWLGA
AAVSGMYAAGASMILGGVAQMLAPKARTPRTQTTDNGKQNTYFSSLDNMVAQGNVLPVLYGEMRVGSRVVSQEISTADEG
DGGQVVVIGR
>SEQF1516_EDU84879.1 hypothetical protein ECH7EC4501_1594 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSPRHEGFISYCSNHQQTPTYLQLNIHNNLTLRHYFRYGYA
>SEQF1516_EDU84880.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNFVEEGKTVAIVASAAISSGDLVQVGDVFAVALTDIPQGETGDGMTEGVFMLPKLKTDDMKTGKKVYLKSGKVQLTN
SGSDPLVGVVWADAGTSAEEVPVKLNV
>SEQF1516_EDU84881.1 aconitase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSSHNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGM
ERFPLPYVLTNCHNSLCAVGGTINGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTM
AVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVKNKVMEFVGPGVAALSTDFRNSV
DVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQLNPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTD
ILREIEIESERVAHGKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPSSQPVFMDL
AKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREGSKPANGQMSAVALMDARSIAATAANGGYLT
SASELDCWDNVPEYAFDVTPYKNRVYQGFVKGAAQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGE
TSSYRSNPIGLAEFTLSRRDPGYVGSSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPLQTEIGSMVYAVKPGDG
SAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQMVEAPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAP
VTEITLYMESLTAEEREIIKAGSLINFNKNRQM
>SEQF1516_EDU84882.1 bacteriophage Lambda NinG protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMAKPARRRCKNDECREWFHPAFANQWWCSPECGTKIALERRSKEREKAEKAEKAAEKKRRREEQKQKDKLKIQKLALKP
RSYWIKQAQQAVHAFIRERDRDLPCISCGTLTSAQWDAGHYRTTAAAPQLRFDERNIHKQCVVCNQHKSGNLVPYRVELI
SRIGQEAVEEIESNHNRYRWTVEECRAIKAEYQQKLKKLRNSRSEVA
>SEQF1516_EDU84883.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDPFSRLAARMDAITVRKMGKTASINDVDMTVIPGETLAELNALSGPAVSLVVFSSGYRPRRGDRVVYDGQQWTVTRHE
RFNGKPMIFIE
>SEQF1516_EDU84884.1 serine/threonine-protein phosphatase 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIYERIDGSKYRNIWVVGDLHGCYTNLMKKLETIGFDTKKDLLISVGDLVDRGTENVECLELITFPWFRAVRGNHEQMM
IDGLSERGNVNHWLLNGGGWFFNLDYDKEILAKALAHKADELPLIIELVSKGKKYVICHADYPCDKYEFGKPVDHQQVIW
NRERISNSQDGIVKEIKGADTFIFGHTPAVKPLKFANQMYIDTGAVFCGNLTLIQVQGEGA
>SEQF1516_EDU84885.1 phage terminase large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNQETAKAARTDSGYILRAPRRMRVADAVAQYMRVPMGAGNSVPWDPLVAPYVIEPMNCLASREYDAVIFVGPARTGKT
IGLIDGWVIYNVICDPADMLIIQMTEEKAREHSKKRLARTFRVSPEVVSRLSPNKNDNNVYDRTFLAGNYLKIGWPSVNI
MSSSDYKCVALTDYDRFPEDIDGEGDAFSLASKRTTTFMSSGMTLVESSPGRDVKDVKWRRTSPHEAPPTTGILSLYNRG
DRRRWYWPCPHCGEYFQPCGDVVAGFRDIADPVLASEAAYIQCPSCSGRIMPEQKRELNGRGVWLRDGESINADGSRYGD
PRRSRIASFWMEGPAAAYQTLSQLVYKLLTAEQEYETTGSEETLKTVINTDWGLPYLPRASMEQRKSELLEQRAEPVPSS
SVPDGVNFLVATVDVQAGRHRRFVVQVTGYGSRGERWIIDRYNITQSLRGDSDGESQRIDPASYPEDWDVLLTDVFHKSW
PLASDPSQQMRLMAMAVDSGGEDGVTDNAYKFWRRCRRDGLGKRIYLFKGDSIRRAKLITRTFPDNTGRTGRRAQAAGDV
PLWLLQTDALKDRVNNALWRDSPGPGYVHFPDWLGSWFYDELTYEERSSDGKWSKPGRGANEAFDLMVYAEALVILHGYE
KIRWPDAPGWASRETWLESVPDSTEPSPSPEPVSTPVKKQKRKKTVTDDVNPWLTSGGWL
>SEQF1516_EDU84886.1 gifsy-1 prophage VmtH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDQIANLVIDLGIDAAEFKNEIPRIKNLLNGAASDAERSSARMQRFMERQTQAARQTMQAASSAATAASVHAQTVEKSAQ
AHERMAREVEQTRQRMEALSQKMREEQAQAMALAEAQDKAAAAFYRQIDSVKQAGAGLQELQRIQQQIRQARNSGGIGQQ
DYLALISEVTAKTRVLTQAEEEATRQKVAFIRQLKEQATRQNLSSSELLRAKAAQLGVSSAAEVYIRKMEQAGKATHSLG
LKSAAARQEIGVLIGELARGNLGALRGSGITLANRAGWIDTLMSPKGMMPGAVIGGIAAAVYGLGKAWYDGQKEGEEFNR
QLSLTGHYAGVTAGQLWTLSRAISGNGITQHAAAGALAQVVGSGAFRGNDIGMVARAAAQMERSVGQSVSDTINQFKRLK
DDPVNAAKALDNELHFLTATQLEQIRVLGEQGRSSDAARIAMSALAEETGRRTADIDNNLNALGSTLKYLSDLWSRFWDA
AMNIGREDSLDEQIAALQEKVSRAKRLPWTASSSQVEYDQQRLNDLQEKKRQKDLQDAKEQAERNYQEQQKRRNAENAAL
NRMNETEAARHQREIARINAMQYADQAVRDAAIQRENERYEKALASGKKKTRETRNDEATRLLLQYSQQQAQVEGQIAAA
RQSAGIATERMTEARKQLLALQQRISDLDGKKLTADEKSVLARKDELIQALTLLDVKQQELQKQTALNELKKKTIQLTSQ
LAEEERAQRQQHDLDIATVGMGDQQRQRYQVQLSLRQKYQQQLEQLRRDSEQKGTYNTDDYRKAEQALTESLNRQLNENR
RYWQQLEVVQGNWKNGVLRAFQDFTVDADNTAETAEQVFSSAFSNMGNGLATFVTTGKLNFKSFTSSVLSDMAKILAQAT
MMKSIKGIGSVLGFDLSSLSLNANGGIYQSADLSRYSGTVVNRPTFFAFAKGAGVMGEAGPEAILPLRRGADGKLGVVAD
IGGSGMAMFSPQYNIEINNDGTNGQIGPAALKAVYDLGKKAAADFMQQQARDGGRLSGAYR
>SEQF1516_EDU84887.1 tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAVQISGVLKDGAGKPIQNCTIQLKARRNSTTVVVNTVASENPDEAGRYSMDVEYGQYSVTLLVEGFPPSHAGTISVYE
DSQPGTLNDFLGAMTEDDARPEALRRFEQMVEEAARHAEEAKKNAGEAETSARNAGISASKAEASAANADTSAEDASESA
RQAAESAASAKKSEEASSSSASEAAQKASESLQSATDAELSKKTAESAAGNAARDATTSTEKARESAESAQSAEQSRIAA
EDAVNRIPTVVGPPGPKGEPGPAGPQGPKGDKGERGDTGPAGATGERGPGGDTGPAGPQGPKGDRGERGETGLTGSTGPQ
GPKGDTGATGPAGPQGPKGETGAAGPVGATGPQGAKGDPGETQIRFRLGPMRIIETNSYGWFPGTDGALITGLTFLDPKD
ATQVQGMFQHLQVRFGDGPWQDVKGLDEVGSDTGRTGE
>SEQF1516_EDU84888.1 zinc transporter ZitB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVIGGFLSGSLALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHT
FGWLRLTTLAAFVNAIALVVITILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHV
LGDLLGSVGAIIAALIIIWTGWTPADPILSILVSLLVLRSAWRLLKDSVNELLEGAPVSLDIAELKRRMCREIPEVRNVH
HVHVWMVGEKPVMTLHVQVIPPHDHDALLDQIQHYLMDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH
>SEQF1516_EDU84889.1 ATP-dependent protease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQAGHQSDADIYIYDEIGFWGVTAKQFISDLNALGDITHINLNINSPGGDVFEGIAIFNALKTHGASITVYVDGVAASMA
SVIAMVGKPVIMPENSFMMIHKPFGFTGGDAEDMRTYADLLDKVEAVLLPAYAQKTGKTTDEIAAMLADETWMSGAECLA
HGFADQVTPAVKAMACIQSKRTEEFKKMPESIRNMITPPRNSAPRVQDDGPAASRTPVQAAAPVVDENSIRAQVLAEQKA
RVNGINDLFAMFGGRYQTLQAQCLADPECSLEQAREKLLNEMGRESTPSNKNTPAHIYAGNGNFVGDGIRQALMARAGFE
KTERDNVYNGMTLREYARMSLTERGIGVSSYNPMQMVGAAFTHSTSDFGNILLDVANKAILQGWEDAPETYEQWTRKGQL
SDFKIAHRVGMGGFSALRQVREGAEYKYVTTGDKQATIALATYGELFSITRQAIINDDLNMLTDVPMKLGRAAKSTIADL
VYAILTSNPKISTDNVSLFDKAKHANVLESAAMDVASLDKARQLMRVQKEGERHLNIRPAFVLVPTAMESVANQVIRSSS
VKGADINAGIINPVKDFATVIAEPRLDDNSQTTFYLAASKGSDTIEVAYLNGVDTPYIDQMEGFSVDGVTTKVRIDAGVA
PVDHRGLVKCTA
>SEQF1516_EDU84890.1 biotin biosynthesis protein BioC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATVNKQAIAAAFGRAAAHYEQHAELQRQSADVLLAMLPQRKYPHVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLAQA
RQKDAADHYLAGDIESLPLATATFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQAWQAVDERP
HANRFLPPDEIEQSLNGVHYQHRIQPITLWFDDALSAMRSLKGIGATHLHEGRDQRILTRSQLQRLQLAWPQQQGRYPLT
YHLFLGVIVRE
>SEQF1516_EDU84891.1 phage minor tail protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDIPQETHHETTRLTQSAQAVLWEIDLTEVGGERYFFCNEQNEKGEPVTWQGRQYQAYPIQGTGFELNGKGSSARPTLT
VSNLHGMVTGMAEDLQSLVGGTVVRRKVYARFLDAVNFVNGNSDADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
AVFPGRIMLANTCTWTYRGDECGYHGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNVGNFGGFLSINKLSQ
>SEQF1516_EDU84892.1 host specificity protein J [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPIEGPVDGLKSVLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEG
FESSGSETVLGTEVKYDTPITRTITSANIDRLRFTFGVQALRETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
SQYLASVVVDNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALVGVQVDSEQFGSQQVSRNYHLRG
RILQVPSNYDPEKRTYSGIWDGTLKPAYSNNMAWCLWDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTE
PRITCNAYLTTQRKAWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSALKDRHNAVE
VNWTDPDNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLWLIKTELLETQTVDFSVGAEGLRHVPGDVIE
ICDDDYAGISIGGRVLAVNSQTRTLTLDREITLPSSGTTLISLVDGSGNPVSVEVQSVTDGVKVKVSRVPDGVAEYSVWG
LKLPTLRQRLFRCVSIRENDDGTYAITAVQHVPEKEGIVDNGAHFDGDQSSTVNGVTPPAVQHLTAEVSADSGEYQVLAR
WDTPKVVKGVSFLLRLTVAADDGSERLVSTARTTETTYRFTQLALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSQI
ELTPGYFQITATPHLAVYDPTVQFEFWFSETRIADIRQVETSARYLGTALYWIAASINIKPGHDYYFYIRSVNTVGKSAF
VEAVGRASDDAEGYLDFFKGKITESHLGKELLEKVDLTEDNASRLDEFSKEWKDANDKWNAMWGVKIEQTKDGKHYVAGI
GLSMEDTEEGKLSQFLVAANRIAFIDPANGNETPMFVAQGNQIFMNDVFLKRLTAPTITSGGNPPVFSLTSDGKLTAKNA
DISGSVNANSGTLNNVTVNENCTIKGMLEATQVRGDFVKAVSKSFPKQAGTWGNTETPNGTVTVTISDDHNFDRQIIIPP
IIFNGIAYSDPGSGNNPGGTRYTGYGFEVRKNGVLIASRETKGAIPGSYSAVIDMPSGRGSVTLEFKVFHKGNQRAGNIT
DCTVIVTKKAASGISIR
>SEQF1516_EDU84893.1 phosphatidylethanolamine-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPAGTKSFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGF
GSGLVAMPDGVLQTRTDFGKTGYDGAAPPKGETHRYIFTVHALDVERIDVDEGASGAMVGFNVHFHSLASASITAMFS
>SEQF1516_EDU84894.1 anti-termination protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTQYLQYVREQLMAATADLNGATKGQLEAWQEHAQFDTGTYKRKKPRILDVVTGKMITLDNTPTSGKQSYAKGSSIALV
SPVEFSTSSWRRAVLSLDEHQKAWLLWCYSESVRWGHQVTITQWAWSEFKDLLSNRKIAGKTLDRLKTLIWLAAQDVKSE
LAGREAYEYQTLASLVGVTTKNWSETFTERWVAMKHIFLQLDSDALLLVTRTRSKQKAAFLQQNIAKLD
>SEQF1516_EDU84895.1 biotin synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVSTLLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQ
VLESARKAKAAGSTRFCMGAAWKNPHERDMSYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEF
YGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPESVPINMLVKVKGTPLADNDDVDA
FDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMCFMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAG
DNEQQQRLEQALMTPDTDEYYNAAAL
>SEQF1516_EDU84896.1 8-amino-7-oxononanoate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNFSSNDYLGLSHHPQIIRAWKQGAEQFGVGSGGSGHVS
GYSVAHQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSQLRRFVHNDVTHLAR
LLASPCPGQQLVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRGTCWLQKVKPELLVVTFGKGFGV
SGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQALRASLAVIRSDEGDARREKLAALITRFRAGVQDLPFTLADSCSAI
QPLIVGDNSRALQLAEKLRQQGCWVTAIRPPTVPSGTARLRLTLTAAHEMQDIDRLLEVLHGNG
>SEQF1516_EDU84897.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEDETLGFFKKTSSSHARLNVPALVQVAALAIIMIRGLDVLMIFNTLGVRGIGEFIHRSVQTWSLTLVFLSSLVLVFIEI
WCAFSLVKGRRWARWLYLLTQITAASYLWAASLGYGYPELFSIPGESKREIFHSLMLQKLPDMLILMLLFVPSTSRRFFQ
LQ
>SEQF1516_EDU84898.1 sugar phosphatase SupH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVKVIVTDMDGTFLNDVKTYNQPRFMAQYQELKKRGIEFVVASGNQYYQLISFFPELKDEISFVAENGALVYEHGKQLF
HGELTRHESRIVIGELLKDKQLNFVACGLQSAYVSENAPEAFVALMAKHYHRLKPVKDYQEIDDVLFKFSLNLPDEQIPL
VIDKLHIALDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWDLSPQNVVAIGDSGNDAEMLKMARYSFAMGNAAENIK
QIARYATDDNNHEGALNVIQAVLDNTSPFNS
>SEQF1516_EDU84899.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVNSSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSVSIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVI
LVTMSCALVGMMILSLALWLTSPLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMA
LTAFGVPATVHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQHGEKGVPFYRDIQLLLIGVVVLAMAFAEGSANDWLPL
LMVDGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFIDRYSRVAVVRASALMGALGIGLIIFVDSAWVAGVSVVLWGLGASL
GFPLTISAASDTGPDAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLRSAMLVVLALVILAAIVAKAVAKPDTKTQTAME
NS
>SEQF1516_EDU84900.1 glutaredoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTVIFGRPGCPYCVRAKDLAEKLSNERDDFQYQYVDIRAEGITKEDLQQKAGKPVETVPQIFVDQQHIGGYTDFAAWVK
ENLDA
>SEQF1516_EDU84901.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRAIGKLPKSVLILEFIGMMLLAVALLSVSDSLSLPEPFSRPEVQILMIFLGVLLMLPAAVVVILQVAKRLAPQLMNRPP
QYSRSEREKDNDANH
>SEQF1516_EDU84902.1 glutathione ABC transporter, permease protein GsiC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEADAQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLS
MVSRRPVADEIARRFMPTLWLTITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMLLIQVFSVELG
WLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWVVLKHGLRNAMIPVVTMMGLQFG
FLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEILLFSLEFILINLVVDVLYAAINPAIRYK
>SEQF1516_EDU84903.1 transcriptional regulator, TetR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGSMTYYFSGIDELLLEAFSSFTEIMSRQYQAFFSDVSD
AQGACQAITDMIYSSQVATPDNMELMYQLYALASRKPLLKTVMQNWMQRSQQTLEQWFEPGTARALDAFIEGMTLHFVTD
RKPLSREEILRMVERVAG
>SEQF1516_EDU84904.1 biofilm regulator BssR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFVDRQRIDLLNRLIDARVDLAAYVQLRKAKGYMSVSESNHLRDNFFKLNRELHDKSLRLNLHLDQEEWSALHHAEEALA
TAAVCLMSGHHDCPTVITVNADKLENCLMSLTLSIQSLQKHAMLEKA
>SEQF1516_EDU84905.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHKQRWAGAICCFVLFIVVCLFLATHMKGAFRAAGHPEIGLLFFILPGAVASFFSQRREVLKPLFGAMLAAPCSMLIMR
LFFSPTRSFWQELAWLLSAVFWCALGALCFLFISSLFKPQHRKNQ
>SEQF1516_EDU84906.1 glucose / sorbosone dehydrogenase protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHRQFFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLPDNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAH
GQGGLLDVVLAPDFAQSRRIWLSYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQGMAMNPWSNALWLNEHGPRGGDE
INIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAGTEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIV
MSVNGDKVTEDGRILTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN
>SEQF1516_EDU84907.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWLRTFAGGFVGLIRRASVASDISTVPVPDAAWTPYPAYIVHKFL
>SEQF1516_EDU84908.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGVYKARRFSQSTKKLGIHDKVLMAAAEEVMQGIWEADLGSGVIKKRLPLQQGKSGGARTIIFFKSANHVFFYDGWSKSG
LSSKGSKEIEDDELAAYKKMANAFLAFSNKQIEDLIETGFLIEVKNER
>SEQF1516_EDU84909.1 glutathione ABC transporter, ATP-binding protein GsiA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPHSDELDAGNVLAVENLNIAFMQDQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLL
RRRSRDVIELSEQSAAQMRHVRGADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQT
ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVL
VMYQGEAVETGTVEQIFHAPQHPYTRALLAAVPQLGAMKGLDYPRRFPLISLEHPAKQAPPIEQKTVVDGEPVLRVRNLV
TRFPLRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALR
RDIQFIFQDPYASLDPRQTIGDSIIEPLRVHGLLPGKEAVARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARALAL
NPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYT
RKLLAAVPVAEPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR
>SEQF1516_EDU84910.1 putrescine ABC transporter, permease protein PotI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNLPVVRSPWRIVILLLGFTFLYAPMLMLVIYSFNSSKLVTVWAGWSTRWYGELLRDDAMMSAVGLSLTIAACAATAAA
ILGTIAAVVLVRFGRFRGSNGFAFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVIS
SRLRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAVISGWLLAFTLSLDDLVIASFVSGPGATTLPMLVFSSVRMGVNP
EINALATLILGAVGIVGFIAWYLMARAEKQRIRDIQCARRG
>SEQF1516_EDU84911.1 putative transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVLVVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPN
FFSIFFRDGKNYLMLALVMVGSALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLS
LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAYRVGPELVAWTDGKNLRELGIYR
QTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYPDAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLA
QLKLTDHGCFLNRVIRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVIGLMIGMIT
FQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLMVFMAGVGLSAGSGINNGLGAIGGQMLIAGL
IVSLVPVVICFLFGAYVLRMNRALLFGAMMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGL
G
>SEQF1516_EDU84912.1 NAD dependent epimerase/dehydratase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPQRILVLGASGYIGQHLVRTLSQQGHQILAAARHVDRLAKLQLANVSCHKVDLSWPDNLPALLQDIDTVYFLVHSMGEG
GDFIAQERQVALNFRDALREVPVKQLIFLSSLQAPPHEQSDHLRARQATADILREANVPVTELRAGIIVGAGSAAFEVMR
DMVYNLPVLTPPRWVRSRTTPIALENLLHYLVALLDHPANEHRIFEAAGPEVLSYQQQFEHFMAVSGKRRWLIPIPLPTR
WISVWFLNVITSVPPTTARALIQGLKHDLLADDTALRALIPQRLIAFDDAVRRTLKEEEKLVNSSDWGYDTQAFARWRPE
YGYFAKQAGFTVKTSASLAALWQVVNQIGGKERYFFGNILWQTRALMDRAIGHKLAKGRPEREYLQTGDAVDSWKVIVVE
PEKQLTLLFGMKAPGLGRLCFTLEDKGDYRTIDVRAFWHPHGMPGLFYWLLMIPAHLFIFRGMAKRIARLAEQSTD
>SEQF1516_EDU84913.1 arginine ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDL
RRNVGMVFQQYNLWPHLTVQQNLIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEP
QVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGHIVEQGDASCFTEPQTEAFKNYL
SH
>SEQF1516_EDU84914.1 arginine ABC transporter, periplasmic arginine-binding protein ArtI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKVLIAALIAGFSLSATAAETIRFATEASYPPFESIDANNQIVGFDVDLAQALCKEIDATCTFSNQAFDSLIPSLKFRR
VEAVMAGMDITAEREKQVLFTTPYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAK
LDLQNGRIDSVFGDTAVVTEWLKDNPKLAAVGDKVTDKDYFGTGLGIAVRQGNTELQQKLNTALEKVKKDGTYETIYNKW
FQK
>SEQF1516_EDU84915.1 sulfatase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLTLKESLVTRSRVFSPWTAFYFLQSLLINLGLGYPFSLLYTAAFTAILLLLWRTLPRVQKVLVGVSSLVAACYFPFAQ
AYGAPNFNTLLALHSTNMEESTEILTIFPWYSYLVGLFIFALGVIAIRRKKENEKARWNTFDSLCLVFSVATFFVAPVQN
LAWGGVFKLKDTGYPVFRFAKDVIVNNNEVIEEQERMAKLSGMKDTWTVTAVKPKYQTYVVVIGESARRDALGAFGGHWD
NTPFASSVNGLIFADYIAASGSTQKSLGLTLNRVVDGKPQFQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRAD
EVYFLKEGNFEADKNTKDEALLDMTAQVLAQEHSQPQLIVLHLMGSHPQACDRTKGKYETFVQSKETSCYLYTMTQTDDL
LRKLYDQLRNSGSSFSLVYFSDHGLAFKERGKDVQYLAHDDKYQQNFQVPFMVISSDDKAHRVIKARRSANDFLGFFSQW
TGIKAKEINIKYPFISEKKAGPIYITNFQLQKVDYNHLGTDIFDPKP
>SEQF1516_EDU84916.1 citrate transporter family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLPFLRTLQGDRFFQLLILVGIGLSFFVPFAPKSWPAAIDWHTIITLSGLMLLTKGVELSGYFDVLGRKMVRRFATERR
LAMFMVLAAALLSTFLTNDVTLFIVVPLTITLKRLCEIPVNRLIIFEALAVNAGSLLTPIGNPQNILIWGRSGLSFAGFI
AQMAPLAGAMMLTLLLLCWCCFPGKALQYHTGVQTPEWKPRLVWSCLGLYIVFLTALEFKQELWGLVIVAAGFALLARRV
VLSVDWTLLLVFMAMFIDVHLLTQLPALQGVLGNVSHLSEPGLWLTAIGLSQVISNVPSTILLLNYVPPSLLLAWAVNVG
GFGLLPGSLANLIALRMANDRRIWWRFHLYSIPMLLWAALVGYVLLVMIPAW
>SEQF1516_EDU84917.1 phosphatase YbjI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIKLIAVDMDGTFLSDQKTYNRERFMAQYQQMKAQGIRFVVASGNQYYQLISFFPEIANEIAFVAENGGWVVSEGKDVF
NGELSKDAFTTVVEHLLTRPEVEIIACGKNSAYTLKKYDDAMKMVAEMYYHRLEYVDNFDNLEDIFFKFGLNLSDELIPQ
VQKTLHEAIGDIMVPVHTGNGSIDLIIPGVHKANGLRQLQKLWGIDDSEVVVFGDGGNDIEMLRQAGFSFAMENAGNAVV
AAAKYRAGSNNREGVLDVIDKVLKHEAPFDQ
>SEQF1516_EDU84918.1 arginine ABC transporter, periplasmic arginine-binding protein ArtJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLVLAALLASCAFGASAAEKINFGVSATYPPFESMDANNQIVGFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRK
YDAVISGMDITPDRSKQVSFTTPYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAF
IDLKNSRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLEKLNNALAAIKADGTYQQISDQW
FPQ
>SEQF1516_EDU84919.1 putrescine ABC transporter, permease protein PotH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTLEPAAQSKPPGGFKLWLSQLQMKHGRKLVIALPYIWLILLFLLPFLIVFKISLAEMARAIPPYTELMEWADGQLSIT
LNFGNFLQLTGDPLYFDAYLQSLQVAAISTFCCLLIGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKN
NGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYVPFMVLPIYTALIRIDYSLVEAALDLGARPLKTFFTVIVPLTKGG
IIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQEFFNNRDWPVASAVAIIMLLLLIVPIMWFHKHQQKSVGEHG
>SEQF1516_EDU84920.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASTFTSDTLPADHKAAIRQMKHALRAQLGDVQQIFNQLSDDIATRVAEINALKAQGDAVWPVLSYADIKAGHVTAEQRE
QIKRRGCAVIKGHFPREQALGWDQSMLDYLDRNRFDEVYKGPGDNFFGTLSASRPEIYPIYWSQAQMQARQSEEMANAQS
FLNRLWTFESDGKQWFNPDVSVIYPDRIRRRPPGTTSKGLGAHTDSGALERWLLPAYQHVFANVFNGNLAKYDPWHAAHR
TEVEEYTVDNTTKCSVFRTFQGWTALSDMLPSQGLLHVVPIPEAMAYVLLRPLLDDVPEDELCGVAPGRVLPVSEQWHPL
LIEALTSIPKLEAGDSVWWHCDVIHSVAPVENQQGWGNVMYIPAAPMCEKNLAYAHKVKAALEKGASPGDFPREDYETNW
EGRFTLADLNIHGKRALGMDV
>SEQF1516_EDU84921.1 glutathione ABC transporter, periplasmic glutathione-binding protein GsiB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARAVHRSGLVALGIATALMASCAFAAKDVVVAVGSNFTTLDPYDANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYT
VSDDGITYTVKLREGIKFQDGTDFNAAAVKANLDRASDPANHLKRYNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAH
PATAMISPAALEKYGKEIGFHPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSITWRPVADNNTRAAMLQTGEAQF
AFPIPYEQAALLEKNKNIELMASPSIMQRYISMNVTQKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIAY
AQSYKPWPYDPVKARELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEVEGKGQKES
GVRMFYTGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQALKTNDPAEKTRLYKAAQDIIWQESPWIPL
VVEKLVSAHSKNLTGFWIMPDTGFSFEDADLQ
>SEQF1516_EDU84922.1 MiaB-like tRNA modifying enzyme YliG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDDADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVT
GCLGAKEDQIREVHPKVLEITGPHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
SMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTSMVSLCEQLSKLGIWTRLHYVYP
YPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMKRPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLL
DFLKEARLDRVGCFKYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDEEGAIGRSM
ADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV
>SEQF1516_EDU84923.1 putrescine ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDAIPRPQAKTRKALTPLLEIRNLTKSYDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPSAGQIMLDG
VDLSQVPPYLRPINMMFQSYALFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL
ARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEH
PTTRYSAEFIGSVNVFEGVLKERQEDGLVLYSPGLVHPLKVDADASVVDNVPVHVALRPEKIMLCEEPPANGCNFAVGEV
IHIAYLGDLSVYHVRLKSGQMISAQLQNAHRHRKGLPTWGDEVRLCWEVDSCVVLTV
>SEQF1516_EDU84924.1 glycyl-radical enzyme activating protein family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARTQDLLYDPRLCLEGCELCAKTAPEVIERALNGLLIHREKL
TPEHLTALTDCCPTQSLTVCGEVKSVEEIMVTVLRDKPFYDRSGGGLTLSGGEPFMQPEMATALLQASHEAGIHTAVETC
LHVPWKYIAPSLPYIDLFLADLKHVADAPFKQWTDGNAARVLDNLKKLAAAGKKIIIRVPLIQGFNADETSVKAITDFAA
DELHVGEIHFLPYHTLGINKYHLLNLPYDAPEKPLDAPELLDFAQQYACQKGLTATLRG
>SEQF1516_EDU84925.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSGLLIILVPLIVGYLIPLRQQAALKVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSITVILLCNIAAL
MWLERGLPWRNHHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQ
IVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLI
PGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA
>SEQF1516_EDU84926.1 hypothetical protein ECH7EC4501_3679 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKGKTTLPKTISSTDNSFRARSRWCSGCALQNYLLFLTFS
>SEQF1516_EDU84927.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNCLLLGALLMGFTGVAMAQSVTVDVPSGYKVVVVPDSVSVPQAVSVATVPQTVYVAPAPAPAYHPHPYVRHLASVGEG
MVIEHQIDDHHH
>SEQF1516_EDU84928.1 multidrug translocase MdfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVVEQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIG
RRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLV
GAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKNGRFVAGALALGFVSLPLLAWIA
QSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLARLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGL
SIYAFGIGLANAGLVRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWLSLMVIFLK
DKQMGNSHEG
>SEQF1516_EDU84929.1 molybdopterin biosynthesis protein MoeA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDVVSPLDVPGFDNSAMDGYAVRLADITSGQPLPVAGKS
FAGQPYHGEWPAGTCIRIMTGAPVPEGCEAVVMQEQTEQTDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAE
LPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGCEVINLGIIRDDPHALRAAFIEA
DSQADVVISSGGVSVGEADYTKTILEELGEIAFWKLAIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLS
GNTASGLPARQRVRTASRLKKTPGRLDFQRGVLHRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGNVEVGEWVE
VEPFNALFGGL
>SEQF1516_EDU84930.1 molybdopterin synthase sulfurylase MoeB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLVVGLGGLGCAASQYLASAGVGNLTLLDFDSVSLSNLQRQTLHSDA
TVGQPKVESARDALTRINPHIAITPVNALLDDAELAALIAEHNLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQ
ITVFTYQDGEPCYRCLSRLFSENALTCVEAGVMAPLIGVIGSLQAMEAIKLLAGYGKPASGKIVMYDAMTCQFREMKLMR
NPGCEVCGQ
>SEQF1516_EDU84931.1 putrescine ABC transporter, periplasmic putrescine-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTALNKKWLSGLVAGALMAVSVGTLAAEQKTLHIYNWSDYIAPDTVANFEKETGIKVVYDVFDSNEVLEGKLMAGSTGFD
LVVPSASFLERQLTAGVFQPLDKSKLPEWKNLDPELLKLVAKHDPDNKFAMPYMWATTGIGYNVDKVKAVLGENAPVDSW
DLILKPENLEKLKSCGVSFLDAPEEVFATVLNYLGKDPNSTKADDYTGPATDLLLKLRPNIRYFHSSQYINDLANGDICV
AIGWAGDVWQASNRAKEAKNGVNVSFSIPKEGAMAFFDVFAMPADAKNKDEAYQFLNYLLRPDVVAHISDHVFYANANKA
ATPLVSAEVRDNPGIYPPADVRAKLFTLKVQAPKIDRVRTRAWTKVKSGK
>SEQF1516_EDU84932.1 undecaprenyl-diphosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLENLNLSLFSLINATPDSAPWMISLAIFIAKDLITVVPLLAAVLWLWGLTAQRQLVIKIAIALAVSLLVSWTMGHLFPH
DRPFVENIGYNFLHHAADDSFPSDHGTVIFTFALAFLCWHRLWSGSLLMVLAVVIAWSRVYLGVHWPLDMLGGLLAGMIG
CLSAQIIWQAMGHKLYQRLQSWYRFCFALPIRKGWVRD
>SEQF1516_EDU84933.1 YbiS protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLKTLFAAAFAVVGFCSTASAVTYPLPTDGSRLVGQNQVITIPEGNTQPLEYFAAEYQMGLSNMMEANPGVDTFLPKGG
TVLNIPQQLILPDTVHEGIVINSAEMRLYYYPKGTNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAEYR
AAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNEDIKFLFEKVPVGTRVQFIDEPVKATT
EPDGSRYIEVHNPLSTTEAQFEGQEIVPITLTKSVQTVTGQPDVDQVVLDEAIKNRSGMPVRLN
>SEQF1516_EDU84934.1 DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDKLQMMLEDAKELNALGLMSDSEVDAIAVMVKAREVSARIAKVKSMTGEEIKAIRTRYGMSQSVLAHTMGMSKESVSK
WERNEIKPSGPALRILNTLAIKGPEVFAK
>SEQF1516_EDU84935.1 diguanylate cyclase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRINKFVLTVSLLIFIMISAVACGIYTQMVKERVYSLKQSVIDTAFAVANIAEYRRSVAIDLINTLNPTEEQLLVGLRT
AYADSVSPSYLYDVGPYLISSDECIQVKEFEKNYCADIMQVVKYRHVKNTGFISFDGKTFVYYLYPVTHNRSLIFLLGLE
RFSLLSKSLAMDSENLMFSLFKNGKPVTGDEYNAKNAIFTVSEAMEHFAYLPTGLYVFAYKKDVYLRVCTLIIFFAALVA
VISGASCLYLVRRVINRGIVEKEAIINNHFERVLDGGLFFSAADVKKLYSMYNSAFLDDLTKAMGRKSFDEDLKALPEKG
GYLCLFDVDKFKNINDTFGHLLGDEVLMKVVKILKSQIPVDKGKVYRFGGDEFAVIYTGGTLEELLSILKEIVHFQVGSI
NLSTSIGVAHSNECTTVERLKMLADERLYKSKKNGRAQISWQ
>SEQF1516_EDU84936.1 fructose-6-phosphate aldolase 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELYLDTSDVVAVKALSRIFPLAGVTTNPSIIAAGKKPLEVVLPELHEAMGGQGRLFAQVMATTAEGMVNDARKLRSIIA
DIVVKVPVTTEGLAAIKMLKAEGIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGGSGIQTVTDLHQLLKMHAPRA
KVLAASFKTPRQALDCLLAGCESITLPLDVAQQMISYPAVDAAVAKFEQDWQGAFGRTSI
>SEQF1516_EDU84937.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRYRSLSLLIPCALLLSACTTVTPAYKDNGPRTGSCVQGGPDSVAQQFYDYHIQHRSNDITALRPYLSDKLATLLSDASR
DNSHRELLSSDPFSSRTTLPDSAHVASASTIPNRDARNIPLRVDLKQGDQGWQDEVLMIQEGQCWVIDDVRYLGGSVHAT
AGTLRQSIENR
>SEQF1516_EDU84938.1 23S rRNA (uracil-5-)-methyltransferase RumB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQCALYDAGRCRSCQWITQPIPEQLSAKTADLKNLLADFPVEEWCAPVSGPEQGFRNKAKMVVSGSVEKPLLGMLHRDGT
PEDLCDCPLYPASFAPVFAALKPFIARAGLTPYNVARKRGELKYILLTESQSDGGMMLRFVLRSETKLAQLRKALPWLQA
QLPQLKVITVNIQPVHMAIMEGETEIYLTEQQALVERFNDVPLWIRPQSFFQTNPAVASQLYATARDWVRQLPVKHMWDL
FCGVGGFGLHCATPDMQLTGIEIALEAIACAKQSAAELGLTRLQFQALDSTQFATAQGEVPELVLVNPPRRGIGKPLCDY
LSTMAPRFIIYSSCNAQTMAKDIRELPGYRIERVQLFDMFPHTAHYEVLTLLVKM
>SEQF1516_EDU84939.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVGGRSGAYEKELRKAREIAFEELGSQARALGADAVVGI
DIDYETVGQNGSMLMVSVSGTAVKTRR
>SEQF1516_EDU84940.1 tetratricopeptide repeat protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSLVVPGLDTLRQWLDDLGMSFFECDNCQALHLPHMQNFDGVFDAKIDLIDNTILFSAMAEVRPSAVLPLAADLSAINA
SSLTVKAFLDMQDDNLPKLVVCQSLSVMQGVTYEQFAWFVRQSEEQISMVILEANAHQLLLPTDDEGQNNVTENYFLH
>SEQF1516_EDU84941.1 cyclic diguanylate phosphodiesterase (EAL) domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRADSRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEE
IQRAVILKMEMMPFLDSVGLVLDDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGQVIFADFNPSKRPWSVASDDSNNSW
NPAYNCFDRPGKKCISFTLRINGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLFLKQGHEIIAKNQLAREKLIIYN
SEGDYNIIDSVDTEYIEKTSAVPNNALFEIYFYYPGGNLLNASDKLFYLPFAFIIIVLLVVYLMTTRVFRRQFSEMTELI
NTLAFLPDSTDQIEALKIREGDAKEIISIKNSIAEMKDAEIERSNKLLSLISYDQESGFIKNMAIIESNNNQYLAVGIIK
LCGLEAVEAVFGVDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCRENVQTFTRKIAMVNDFDSSFGYRNLRIHKS
AICEPLQGENAWSYAEKLKLAISSIRDHMFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRAILG
AEALCRWVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSQRASLKDDFLLHINVSPWQLNEPHFHERFTT
IMKENGLKANSLCVEITETVIERINEHFYLNIEQLRKQGLRISIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAG
KIVRIIFDLARYNRIPVIAEGVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE
>SEQF1516_EDU84942.1 NAD dependent epimerase/dehydratase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTSFSQQQWIDMKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMGAEFVPADLTELVSSQAKVMLAGID
TLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAVAWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASE
EVINMLSQANPQTRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEACDKLPS
GRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMERLGRKSAKEPPLTHYGVSKLNFDFTLDITRAQE
ELGYQPVITLDEGIEKTAAWLRDHGKLPR
>SEQF1516_EDU84943.1 NADH oxidoreductase hcr [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTMPTNQCPWRMQVHHIKQETPDVWTISLICHDYYPYRAGQYALVSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGV
GSQWLTRDVKRGDYLWLSDAMGEFTCDDKAEDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVRVIYNVRTPQDVIFADEW
RNYPVTLVAENNVTEGFIAGRLTRELLTRVPDLASRTVMTCGPAPYMDWVEQEVKALGVTRFFKEKFFTPVAEAATSGLK
FTKLQPAQEFYAPVGTTLLEALESNNVPVVAACRAGVCGCCKTKVVSGEYTVSSTMTLTDAEIAEGYVLACSCHPQGDLV
LA
>SEQF1516_EDU84944.1 sulfatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRAIILLFDSLNKRYLPPYGDALTKAPNFQRLAAHAATFENSYVGSMPCMPARRELHTGRCNFLHREWGPLEPFDDSMPE
LLKKAGIYTHLISDHLHYWEDGGENYHNRYSSWEIVRGQEGDHWHASVAQPPIPEVLRVPQKQTGGGVSGLWRHDWANRE
YIQQEADFPQTKVFDAGCAFIHKNHAEDNWLLQIETFDPHEPFHTTEEYLSLYEDNWDGPHYDWPRGRVQESDEAVEHIR
CRYRSLVSMCDRNLGRILDLMDEHDLWRDTMLIVGTDHGFLLGEHGWWAKNQMPYYNEVANNPLFIWNPRSGVKGERRQA
LVQMIDWAPTLYDFFQQPVPPDVQGQPLAKTVSHDEPVRSSAMFGVFSGHANVTDGRYVYMRAALPGREDDIANYTLMSC
KMNSRYPVDEMRALSLAPPFRFTKGLQVLRIPAQEKYKGLNQFGHLLFDLQNDPQQLHPIHDDVIESRMIALLIQLMKDN
DAPPEQFQRLGLA
>SEQF1516_EDU84945.1 arginine ABC transporter, permease protein ArtM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVLVWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEY
PALWHLLSEPWLCALIALSLNSAAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAFERRN
>SEQF1516_EDU84946.1 deoxyribose operon repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METRREERIGQLLQELKRSDKLHLKDAAALLGVSEMTIRRDLNNHSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKR
RAAKLAATLVEPDQTLFFDCGTTTPWIIEAIDNEIPFTAVCYSLNTFLALKEKPHCRAFLCGGEFHASNAIFKPIDFQQT
LNNFCPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMSMAQKHVLVVDHSKFGKVRPARMGDLKRFDIVVSDCCPEDEYV
KYAQTQRIKLMY
>SEQF1516_EDU84947.1 transcriptional regulator MntR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRRAGTPTAKKVTQLVNEEEHVEGFRQVREAHRRELIDDYVELISDLIREVGEARQVDMAARLGVSQPTVAKMLKRLAT
MGLIEMIPWRGVFLTAEGEKLAQESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSEETLDAFRLFTQKHGAK
>SEQF1516_EDU84948.1 glutathione ABC transporter, permease protein GsiD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAALFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSL
QHWFGVDSLGRDIFSRVLVGAQISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVL
GSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTILLRHILPGTVSSIVVFFTMRIGTSIISAASL
SFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPALAIFLTVLAFNLLGDGLRDALDPKIKG
>SEQF1516_EDU84949.1 ribosomal protein S6 modification protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPAASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQF
EMLGSYPLNESVAIARARDKLRSMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAA
ESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGGAASVASITPQEREIAIKAARTM
ALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGIDIAGKMIRWIERHATTEYCLKTGG
>SEQF1516_EDU84950.1 N-acetylmuramoyl-L-alanine amidase AmiD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRVFWLIAVALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRIKVLVIHYTADDFDSSLATLTDKQVSSHYLVPAVPPR
YNGKPRIWQLVPEQELAWHAGISAWRGATRLNDTSIGIELENRGWQKSAGVKYFAPFEPAQIQALIPLAKDIIARYHIKP
ENVVAHADIAPQRKDDPGPLFPWQQLAQQGIGAWPDAQRVNFYLAGRAPHTPVDTASLLELLARYGYDVKPDMTPREQRR
VIMAFQMHFRPTLYNGEADAETQAIAEALLEKYGQD
>SEQF1516_EDU84951.1 pyruvate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEWMSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLH
LINGLFDCHRNHVPVLAIAAHIPSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLP
GDVALKPAPEGATTHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKELVEFAGKIKAPIVHALRGKEHV
EYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQFPYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALL
PLVEEKADRKFLDKALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLKMNGKRRLL
GSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMKLPVKIIVFNNSVLGFVAMEMKAGGYLTDGT
ELHDTNFARIAEACGITGIRVEKASEIDEALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGD
EVIELAKTNWLR
>SEQF1516_EDU84952.1 ascorbate-specific PTS system enzyme IIC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEGVPTMFAKFIDVIQTFLTEPAILIGLLVGIGYALDKKSPIKIITGMVSAMVGLMMVLFGGFQFSATFKPVAEAVSKAY
GVHGYLMDSYAMKAATQIALGDNFGYVGYVFVLAFFTNLLLVLFGRYTGAKGIFLTGNTGVSHSQAVLWLIVFWLGFSWT
TSIIIAGILTGVFWAFSTTLIVKPIAKVTKDAGFTIAHNQMLGLWFFSKFAHKFGDPEKHDAENLKLPGWLAIFNHNVTA
IAIVMTLFVGGFLLSTGIDNVQLMAKGKPWYIYIINLGLQFSMYMVILLQGVRMMVGEINGSFKGWQDRFIPNAIPAVDV
AALLPFSPNAATLGFVFCTFGTIFSMGILLLVHSPIMVLPGFVPLFFSGGPIGVLANRMGGYRSVIICTFLLGIIQTFGT
VWAIPLTGLAENGVGWTGIFDWATVWPAICEVLKFIAATFHLGPYAG
>SEQF1516_EDU84953.1 outer membrane protein X [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDY
NKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDV
GTWIAGVGYRF
>SEQF1516_EDU84954.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFMKILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFT
VLDTVIMGHKELWEVKQERDRIYALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMVCTHMADLDYGELRVYPGNYDEY
MTAATQARERLLADNAKKKAQIAELQSFVSRFSANASKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNAL
EVEGLTKGFDNGPLFKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHEYEFENDLT
VFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFGKLMMQKPNILIMDEPTNHLDMESIESLNMA
LELYQGTLIFVSHDREFVSSLATRILEITPERVIDFSGNYEDYLRSKGIE
>SEQF1516_EDU84955.1 arginine ABC transporter, permease protein ArtQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEFFPLASAAGMTVGLAVCALIVGLALAMFFAVWESAKWRPVAWAGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDG
FTINLGIVEIPVQMQIENFDVSPFLCGVIALSLLYAAYASQTLRGALKAVPMGQWESGQALGLSKSAIFFRLVMPQMWRH
ALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIVAAAIYLVITLLSQYILKRIDLRATRFERRPS
>SEQF1516_EDU84956.1 glutathione S-transferase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITLWGRNNSTNVKKVLLTLEELELPYEQILAGREFGINHDADFLAMNPNGLVPLLRDDESDLILWESNAIVRYLAAQYG
QKRLWIDSPARRAEAEKWMDWANQTLSNAHRGILMGLVRTPPEERDQAAIDASCKECDALFALLDAELAKVKWFSGDEFG
VGDIAIAPFIYNLFNVGLTWTPRPNLQRWYQQLTERPAVRKVVMIPVS
>SEQF1516_EDU84957.1 hydroxylamine reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFD
SPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATA
GKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIID
PTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIF
LLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVN
DLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
>SEQF1516_EDU84958.1 oxygen-insensitive NADPH nitroreductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPTIELTCGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQCSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFC
ADFNRHLQICPDAQLGLAEQLLLGVVDTAMMAQNALTAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP
ADNPDLKPRLPSSILVHENSYQPLDKDALAQYDEQLAEYYLTRGSNNRRDTWSDHIRRTIIKESRPFILDYLHKQGWATR
>SEQF1516_EDU84959.1 low-specificity L-threonine aldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQ
AAHNYLFEAGGAAVLGSIQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKDAWEFTRERN
LALHVDGARIFNAVVAYGSELKELTQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAIRWRKMTGGGMRQSGILAAAGMY
ALKNNVARLQEDHDNAAWMAEQLREAGADVMRQDTNMLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSREQL
AEVAAHWRAFLAR
>SEQF1516_EDU84960.1 serine-type D-Ala-D-Ala carboxypeptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFMTQYSSLLRGLAAGSAFLFLFAPTAFAAEQTVEAPSVDARAWILMDYASGKVLAEGNADEKLDPASLTKIMTSYVVG
QALKADKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNG
YAKKLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFNKIRQPNRNRLLWSSNLNVDGMKTG
TTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEKLLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEA
GSVTIPRGQLKNLKASYTLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGGFFGRMWDFVMMKFHQWFGS
WFS
>SEQF1516_EDU84961.1 phage minor tail protein G [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLKTEQFEYNGVSVTLSELSALQRIEHLALLKRRAEQAESSGNLQVSVEDLVRTGAFLVAMSLWHNHPQKTQSPSMNEA
VMKIEQEVLTTWPADAIARAEDVVLCLSGMSGAVRPDTDITEVAKNNTLTDDDFSAGKSSTAS
>SEQF1516_EDU84962.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEINYQALREKAEKATKGSYIVGHTSVNQHGNLTGVFVCQKWKGEPGGVIAECHVNCLIESDDQAYANAEFIAEANPAT
VLALLDEQERNQQYIKRRDQENEEIALTVGKLRVELEAAENNLIDSECHVAELEEALRDKQALLEASEKRNAKLQSENAY
IRNRYKELDLLIGKNILVMQAAIIEWQATGDAKSGLAWIYNTLFGPGELPDESEKDAQAYFNRKYAPIDEKLMALHKWFW
EQSEAERAAGIRIKRGE
>SEQF1516_EDU84963.1 phage portal protein, lambda family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRTPVLIDVNGVPLRESLSYNGGGAGFGGQMAEWLPPAQSADAALLPALRLGNARADDLVRNNGIAANAVALHKDHIVG
HMFLISYRPNWRWLGMRETAAKSFVDEVEAAWSEYAEGMSGEIDVEGKRTFTEFIREGVGVHAFNGEIFVQPVWDTETTQ
LFRTRFKAVSPKRVDTPGHGMGNRFLRAGVEVDRYGRAVAYHICEDDFPRSGSGRWERIPRELPTGRPAMLHIFEPVEDG
QTRGANQFYSVMERLKMLDSLQATQLQSAIVKAMYAATIESDLDTEKAFEYIAGAPQGQKDNPLINILEKFSSWYDTNNV
TLGGVKIPHLFPGDDLKLQTAQDSDNGFSALEQALLRYIAAGLGVSYEQLSRDYSKVSYSSARASANESWRYFMGRRKFI
AARLATQMFSYWLEEALLRGIIRPPRARFDFYQARSAWSRAEWIGAGRMAIDGLKEVQESVMRIEAGLSTYEKEPALMGE
DYQDIFRQQVRESAERQKAGLSRPVWIAQAYQQQIAESRRPEEETTPRET
>SEQF1516_EDU84964.1 tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVKISGVLKDGTGKPVENCTIQLKARRNSATVVVNTVASENPDEAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYED
SQPGTLNDFLGAMSEDDVRPEALRRFELMVEEAARHAEEAKKNAGEAETSARNAGISASQAEESAANADTSAGDASESAR
QAAESAAAAKQSEEASSSSASAAAQKASESSQSAAEAELSRKTAESAAGNAARDATTATEKARESAESAQSAEQSRIAAE
EAVNRIPTVVGPPGPKGEPGPAGPQGPKGDKGERGDTGPAGATGERGPAGDAGPAGPQGPKGDRGERGETGLTGNAGPQG
PKGDTGAAGPAGPQGPKGETGAAGPVGATGPQGPKGDPGETQIRFRLGPASIIETNSHGWFPGTDGALITGLTFLAPKDA
TRVQVFFQHLQVRFGDGPWQDVKGLDEVGSDTGRTGE
>SEQF1516_EDU84965.1 glucose-1-phosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKTLIAAAVAGVVLLASNAQAQTVPEGYQLQQVLMMSRHNLRAPLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEV
YMGHYMREWLAEQGMVKSGECPPPDTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
SEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQEPGVSGPLKVGNSLVDAFTLQYY
EGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTSPEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLT
ALDFKPYQLHDQNERTPIGGKIVFQRWRDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCPIDADGFCP
MDKFDSVLNEAVK
>SEQF1516_EDU84966.1 enterobacterial Ail/Lom family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKLYAAILSAAICLAVSGAPAWASEHQSTLSAGYLHVSTNVPGSDELNGINVKYRYEFTDTLGMVTSFSYAGDKNRQLT
RYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
GAGVQFNPIESVAIDIAYEGSGSGDWRTDGFIVGVGYKF
>SEQF1516_EDU84967.1 putative prophage tail fibre C-terminus family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNILKKIMQRLCGCGKHDDCEHGQSLTVQLRLGPADILESDENGIIPEQDGVITQVVILDADKKQIQCVVRPLQILRADG
RWENIGGMK
>SEQF1516_EDU84968.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRVLCVVIIVLLVACGALSLGLNHYRDHAIIYKEQRDKKASELELANATITDMQIRQRDVAALDARYSRELADARAENE
TLRADVAAGRKRLRINATCSGTVREATGTSGVDNATGPRLADTAERDYFILRERLMAMQKQLEGAQEYIRTQCIP
>SEQF1516_EDU84969.1 Ni/Fe-hydrogenase 1 B-type cytochrome subunit HyaC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQQKSDNVVSHYVFEAPVRIWHWLTVLCMAVLMVTGYFIGKPLPSVSGEATYLFYMGYIRLIHFSAGMVFTVVLLMRIYW
AFVGNRYSRELFIVPVWRKSWWQGVWYEIRWYLFLAKRPSADIGHNPIAQAAMFGYFLMSVFMIITGFALYSEHSQYAIF
APFRYVVEFFYWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVISTMVNGYRSHKFGKISNKERS
>SEQF1516_EDU84970.1 bacteriophage lambda tail assembly protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTAAEAIRALSMQMPGFRRQMNEGWYQIRIAGDDTAPEAVYARLHEQLGEGTVIHIVPRLAGAGKGGLQIVLGAAAIVG
SFFTAGASMALWGSALAAGGFSATTMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGRQNTYFSSLDNMIAQGNPMPVP
YGEMLVGSRRISQDISTRDEGGDGKVVVIGRQA
>SEQF1516_EDU84971.1 TMAO reductase system sensor TorS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGFALMALLTLTSTLVGWYNLRFISQVEKDNTQALIPTMNMARQLSEASAWELFAAQNLTSADNEKMWQAQGRMLTAQSL
KINALLQALREQGFDTTAIEQQEQEISRSLRQQGELVGRRLQLRQQQQRLSQQIVAAADEIARLAQGQANNAATSAGATQ
AGIYDLIEQDQRQAAESALDRLIDIDLEYVNQMNELRLSALRVQQMVMNLGLEQIQKNAPTLEKQLNNAVKILQRRQIRI
EDPGVRAQVATTLTTVSQYSDLLALFQQDSEISNHLQTLAQNNIAQFAQFSSEVSQLVDTIELRNQHGLAHLEKASARGQ
YSLLLLGMVSLCALILILWRVVYRSVTRPLAEQTQALQRLLDGDIDSPFPETAGVRELDTIGRLMDAFRSSVHALNRHRE
QLAAQVKARTAELQELVIEHRQARAEAEKASQAKSAFLAAMSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGE
SLLTILNDILDYSAIEAGGKNVSVSDEPFEPRPLLESTLQLMSGRVKGRPIRLATAIADDVPTALMGDPRRIRQVITNLL
SNALRFTDEGQIVLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFIQVSGKRGGTGLGLTISSRLAQAMGGELSATSTP
EVGSCFCLRLPLRVATAPVPKTVNQAVRLDGLRLLLIEDNPLTQRITVEMLNTSGAQVVAIGNAAQALETLQNSEPFAAA
LVDFDLPDVNGITLARQLARQYPSLVLIGFSAHVIDETLRQRTSSLFRGIIPKPVPREVLGQLLAHYLQLQANNDLPLDV
SQLNEDAQLMGTEKIHEWLALFTQHALPLLDEIDIARATQDSEKIKRAAHQLKSSCSSLGMRSASQLCAQLEQQPLSAPL
PHEEITRSVAALEAWLNKKDLNAI
>SEQF1516_EDU84972.1 phage recombination protein Bet [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQFIALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVD
GWSRIINENQQFDGMDFEQDNESCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCA
RLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDDDLLPLCSQIFRRDIRASSELTQ
AEAVKVLGFLKQKASEQKVAA
>SEQF1516_EDU84973.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQESKTMKNRKAKILLVRRNAPGVWQWVRLSNRRMGLMKYYGMMDCGFCKKPSAEQNRWKNHLRTKGE
>SEQF1516_EDU84974.1 group 4 capsule (G4C) polysaccharide, lipoprotein YmcC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRPLILSIFALFLAGCTHSQQSMVDTFRASLFDNQDITVADQQIQALPYSTMYLRLNEGQRIFVVLGYIEQEQSKWLSQD
NAMLVTHNGRLLKTVKLNNNLLEVTNSGQDPLRNALAIKDGSRWTRDILWSEDNHFRSATLSSTFSFAGLETLHIAGRDV
LCNVWQEEVTSTLPEKQWQNTFWVDSATGQVRQSRQMLGAGVIPVEMTFLKPAP
>SEQF1516_EDU84975.1 head-tail preconnector protein GP5 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRNLSHIIAAAFNEPLLLEPAYARVFFCALGREMGAASLSVPQQQVQLDAPGMLAETDEYMAGGKRPARVYRVVNGIAV
LPVTGTLVHRLGGMRPFSGMTGYDGIVACLQQAMADSQVRGVLLDIDSPGGQAAGAFDCADMIYRLRQQKPVWALCNDTA
CSAAMLLASACSRRLVTQTSRIGSIGVMMSHVSYAGHLAQAGVDITLIYSGAHKVDGNQFEALPAEVRQNMQQRIDAARR
MFAEKVAMFTGLSVDAVTGTEAAVFEGQSGIDAGLADELVNASDAISVMATALNSNVRGGTMPQLTATEAAAQENQRVMG
ILTCQEAKGREQLATMLAGQQGMSVEQARAILAAAAPQQPVASTQSEADRIMACEEANGREQLAATLAAMPEMTVEKARP
ILAASPQADAGPSLRDQIMALDEAKGAEAQAEQLAACPGMTVESARAVLAAGSGKAEPVSASTTALFERIMANHSPAAVQ
GGVPQTSADGDADVKMLMAMP
>SEQF1516_EDU84976.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSKESLRRRFLQLMTENVKSELLLLMADNNEATSSILADPYGKISHKTLDIITTTLTPLMLQRLKHNINAWVNEELSPP
CLWDSRYACQQKMRIFNLLSPKLR
>SEQF1516_EDU84977.1 hypothetical protein ECH7EC4501_3819 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFHESAICDFRANANSVKPQPIAVLFKTMGAWAVLCFAADDTDARMAIGQEMEMDPTNDEFIIYGAPSNYLLDTCNIYN
KAA
>SEQF1516_EDU84978.1 copper/zinc superoxide dismutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFASTGVCALPPPLPIMFLSIGIINRSDRILHSYCAISSERCLLPCNQQAQSVNGINEGFMKCKIIAAIAMLTAASCGY
AAEQEVPMNLVSADGKEVSIGKITIQETPYGLLFTPALHSLSEGIHGFHVHEKGNCAPALKDGKPVAALSAGGHFDPKNT
GKHLGPWSPDGHPGDLPALFVTHDGKANYPVLAPRLNSLKEIKGRSLMLHAGGDNHHDHPEPLGGGGARMACGIIQ
>SEQF1516_EDU84979.1 hypothetical protein ECH7EC4501_3734 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKGIEVETPASLDLTRAAAFAIRIVAIAVLVWAIRWW
>SEQF1516_EDU84980.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPQQENALRSIARQANSEIKKARQQFPDKNVDDICRSVLKKHRETVTLMGFTPTHLSLAIGMLNGVFKER
>SEQF1516_EDU84981.1 nickel-dependent hydrogenase 1, small subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAWALENKPRIPVVWIHGLECTCCTESFIRSAHPLAKDV
ILSLISLDYDDTLMAAAGTQAEEVFEDIITQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTC
ASWGCVQAARPNPTQATSIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVDRMGRPLMFYGQRIHDKCYRRAH
FDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACSSTRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVVDIPQMGT
HSTADTVGLTALGVVAAAVGVHAVASAVDQRRRHNQQPTETEHQPGNEDKQA
>SEQF1516_EDU84982.1 phage terminase large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNISEQQLNNMMSAVTTALQPLIRALPVTPVEWADQNYYLPKESSYGEGEWKTLPFQIAIMNSMGNDQIRTVNLIKSARV
GYTKMLLGGGGYFIEHKSRNSLLFQPTDSAAEDFMKSHVEATIRNVPCLKDLSPWLGRKHRDNTLTLKRFSSGVGFWCLG
GAAAKNYREKSVDVVCYDELSSFEPDVEKEGSPTLLGDKRIEGSVWPKSIRGSTPKIKGTCQIEKAANESAHFMRFYVPC
PHCGEAQYLKFGDESTPFGLKWEKDSPESVFYLCEHHGCVIHQSELDQSNGRWICENTGMWTRDGLTFFSARGDEIPPPR
SIMFHIWTAYSPFTTWVQIVYDWLDALKDPNGLKTFVNTTLGETWEEAVGEKLDHQVLMDKVVRYTAAVPARVVYLTAGI
DSQRNRFEMYVWGWAPGEEAFLVDKIIIMGRPDEEETLLRVDAAINKKYRHADGTEMTISRVCWDTGGIDGEIVYQRSKK
HGVFRVLPVKGASVYGKPVITMPKTRNQRGVYLCEVGTDTAKEILYARMKADPSPADEATSYAIRFPDDPEIFSQTEAQQ
LVAEELVEKWEKGKMRLLWDNKKRRNEALDCLVYAYAALRVSVQRWQLDLAVLAKSREEETTRPTLKELAAKLSGGVNGY
SR
>SEQF1516_EDU84983.1 torCAD operon transcriptional regulatory protein TorR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQNQPVDLILLDINLPDENGLMLTRALRERSTVGIILVT
GRSDRIDRIVGLEMGADDYVTKPLELRELVVRVKNLLWRIDLARQAQPYTQDNCYRFAGYCLNVSRHTLERDGEPIKLTR
AEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQHGEGYFLAADVC
>SEQF1516_EDU84984.1 tyrosine-protein kinase etk [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTKNMNTPPGSTQENEIDLLRLVGELWDHRKFIISVTALFTLIAVAYSLLSTPIYQADTLVQVEQKQGNAILSGLSDMI
PNSSPESAPEIQLLQSRMILGKTIAELNLRDMVEQKYFPIVGRGWARLTKEKPGELAISWMHIPQLNGQDQQLTLTVGEN
GHYTLEGEEFTVNGMVGQRLEKDGVALTIADIKAKPGTQFVLSQRTELEAINALQETFTVSERSKESGMLELTMTGDDPQ
LITRILNSIANNYLQQNIARQAAQDSQSLEFLQRQLPEVRSELDQAEEKLNVYRQQRDSVDLNLEAKAVLEQIVNVDNQL
NELTFREAEISQLYKKDHPTYRALLEKRQTLEQERKRLNKRVSAMPSTQQEVLRLSRDVEAGRAVYLQLLNRQQELSISK
SSAIGNVRIIDPAVTQPQPVKPKKALNVVLGFILGLFISVGAVLARAMLRRGVEAPEQLEEHGISVYATIPMSEWLDKRT
RLRKKNLFSNQQRHRTKNIPFLAVDNPADSAVEAVRALRTSLHFAMMETENNILMITGATPDSGKTFVSSTLAAVIAQSD
QKVLFIDADLRRGYSHNLFTVSNEHGLSEYLAGKDELNKVIQHFGKGGFDVITRGQVPPNPSELLMRDRMRQLLEWANDH
YDLVIVDTPPMLAVSDAAVVGRSVGTSLLVARFGLNTAKEVSLSMQRLEQAGVNIKGAILNGVIKRASTAYSYGYNYYGY
SYSEKE
>SEQF1516_EDU84985.1 chaperone-modulator protein CbpM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWVFDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDI
AHLKQENRLLRQRLSRFVAHP
>SEQF1516_EDU84986.1 lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEKIKYGLSAAVLALIGAGASAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGAILVDGKPVIPGMKLSKEKCDRVNAI
ERDKALAWVEKNIRVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRINAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
VSRRDQESALACWDIDR
>SEQF1516_EDU84987.1 chaperone protein TorD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTLTAQQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLLKSEPPLTAAVDELENRVATLTVRDDARLELAADFCG
LFLMTDKQAALPYASAYKQDEQEIKRLLVEAGMETSGNFNEPTDHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTA
LRQWLPEFVARCHQYDSFGFYAALSQLLLVLVEGDHQNR
>SEQF1516_EDU84988.1 gpW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTVAELQALRQARLDLLTGKRVVSVQKDGRRIEYTAASLDELNRAINDAESVLGTTRRRRRPLGVRL
>SEQF1516_EDU84989.1 major tail protein V [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDDDWQRLAKVKDLTPGEMTAESYDDNYLDDEDADWTATGQGQKSAGDTSFTLAWKPGEEGQKGLIGWFESGDVRAYKI
RFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGKPSVAEERSKITPVSAIKVTPTSGTVAKGKTTTLTVSFEPESA
TDKTFRAVSADPSKATISVKDMTITVNGVATGKVQIPVVSGNGQFAAVAEVTVTEAGAAG
>SEQF1516_EDU84990.1 hypothetical protein ECH7EC4501_3798 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRQTLPVFKDEYKNSRSTSHFANLFPEKSHISVTLFSD
>SEQF1516_EDU84991.1 curved DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEARFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFSRQ
FQHGDGQSFNAEDFDDIFSSIFGQHARQSRQRPAARGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVSPWEAALGAKVTVPTLKESILLT
IPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMPPKPDENTAALWQQLADAQSSFDPRKDWGKA
>SEQF1516_EDU84992.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDQTLMAIQTKFTIATFIGDEKMFREAVDAYKKWILILKLRSSKSIH
>SEQF1516_EDU84993.1 periplasmic protein TorT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVLLFLLLSLFMLPAFSADNLLRWHDAQHFTVQASMPLKAKRVWKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVL
EAGGYSQLATQQAQIDQCKQWGAEAILLGSSTTSFPDLQKQVANLPVIELVNAIDAPQVKSRVGVPWFQMGYQPGRYLVQ
WAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQEMLERHPEIDVVAGTAIAAEAAM
GEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASDQMVWQGELAVEQAIRQLQGQSVSDNVSPPILVLTPKNADREHIR
RSLSPGGFRPVYFYQHTSAAKK
>SEQF1516_EDU84994.1 IS66 family element, orf1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLDAAAEQPESLAEDPETLSISCEVTFRHGTLRFNGNVSEKLLTLLIQELKR
>SEQF1516_EDU84995.1 group 4 capsule (G4C) polysaccharide, lipoprotein YmcA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKNSYLLSCLAIAVSSACHAEVLTYPDPLGSSQSDFGGTGLLQMPNARIAPEGEFSVNYRDNDQYRFYSTSVALFPWLE
GTIRYTDVRTRKYSQWEDFSGDQSYKDKSFDFKLRLWEEGYWLPQVAFGKRDIAGTGLFDGEYLVASKQAGPFDFTLGMA
WGYAGNAGNITNPFCRVSDKYCHRAESHDAGDISFSDIFRGPASIFGGIEYQTPWNPLRLKLEYDGNNYQNDFAGKLPQA
SHFNVGAVYRAASWADLNLSYERGNTLMFGFTLRTNFNDLRPALRDTPKPAYQPAPESEGLQYTTVANQLTALKYNAGFD
APEIQLRDKTLYMSGQQYKYRDSREAVDRANRILVNNLPQGVEKISVTQKREHMAMVTTETDVASLRKQLAGTAPGQSEP
LQQQRVEAEDLSAFGRGYRIREDRFSYSFNPTLSQSLGGPEDFYMFQLGLMSSARYWFTDHLLLDGGIFTNIYNNYDKFK
SSLLPADSTLPRVRTHIRDYVRNDVYLNNLQANYFADLGNGFYGQVYGGYLETMYAGVGSELLYRPLDASWALGVDVNYV
KQRDWDNMMRFTDYSTPTGFVTAYWNPPTLNGVLMKLSVGQYLAKDKGATIDVAKRFDSGVAVGVWAAISNVSKDDYGEG
GFSKGFYISIPFDLMTIGPNRNRAVVSWTPLTRDGGQMLSRKYQLYPMTAEREVPVGQ
>SEQF1516_EDU84996.1 putative inner membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHKLSAILMAFMLTTPAAFAAPEAANGTEATTGTTGTTTTTTGATTTAATTGGVAAGAVGTATVVGVATAVGVATLAVV
AANDSGDGGSHNTSTTTSTTR
>SEQF1516_EDU84997.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWEEGSDEVLVKAFAKTDKDSLFWGEQTIERKNV
>SEQF1516_EDU84998.1 periplasmic AppA protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAILIPFLSLLIPLTPQSAFAQSEPEPELKLESVVIVSRHGVRAPTKATQLMQDVTPDAWPNWPVKLGWLTPRGGELIA
YLGHYQRQRLVADGLLTKKGCPQPGQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLD
NANVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLNREKQDESCSLTQALPSELKVSADNVSLTGAVSLASM
LTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQFYLLQRTPEVARSRATPLLDLIMIALTPHPPQKQAYGVTLPTS
VLFIAGHDTNLANLGGALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNTPPGEVK
LTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL
>SEQF1516_EDU84999.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATQTEVARHLSLTDRQLRRLQKLPGAPISNKRGQLDLDAWRDFYISYLRRSKNDVPDGDSEDDYEEKLLIARWELTAEQ
AVTQQLKKRTA
>SEQF1516_EDU85000.1 NAD(P)H:quinone oxidoreductase, type IV [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINHILRHVETMARAVAEGASKVDGAEVVVKRVPETMSPQLFEKAGGKTQTAPVATPQELANYDAIIFGTPTRFGNMSGQ
MRTFLDQTGGLWASGALYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPYGATTIA
GGDGSRQPSQEELSIARYQGEYVAGLAVKLNG
>SEQF1516_EDU85001.1 host specificity protein J [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKGGGRAHTPVEAKDNLKSTQMMSVIDAIGEGPIEGPVKGLQSILVNKTPLTDTDGNPVIHGVTAVWRAGEQEQTPPEG
FESSGAETALGVEVTKAKPVTRTITSANIDRLRVTFGVQSLLETTSKGDRNPSSVRLLIQLQRNGNWVTEKDVTINGKTT
SQFLASVILDNLPPRPFNIRMVRETADSTSDQLQNKTLWSSYTEIIDVKQCYPNTAIVGLQVDAEQFGGQQMTVNYHIRG
RIIQVPSNYDPEKRTYSGIWDGSLKPAYSNNPAWCLWDMLTHPRYGMGKRLGAADVDKWALYAIAQYCDQMVPDGFGGTE
PRMTFNAYLSQQRKAWDVLSDFCSAMRCMPVWNGQTLTFVQDSPSDVVWPYTNSDVVVDDNGVGFRYSFSALKDRHTAVE
VNYTDPQNGWQTSTELVEDPEAILRYGRNLLKMDAFGCTSRGQAHRAGLWVIKTGLLETQTVDFTLGSQGLRHTPGDIIE
ICDNDYAGTMTGGRVLSIDAASRTLTLDREVTLPETGAATVNLINGSGKPVSVAITAHPAPDRIQVSTLPDGVETYGVWG
LSLPSLRRRLFRCVSIRENTDGTFAITAVQHVPEKEAIVDNGARFEPQSGTLNSVIPPAVQHLTVEVSAADGQYLAQAKW
DTPRVVKGVRFSLRLTSGSGEGSRLVTTAITADTEHRSSGLPPGEYTLTVRAINSYGQQGEPATTTFRINAPAVPATIEL
TPGYFQITAVPRLAVYDPTVQFEFWFSETKIADTSQVETSARYLGTGSQWSVSGPHIKPGKDFWFYVRSVNLVGKSAFVE
ASGRASNDAEGYLGLFREKIGKLHLAQGLWELIDNSQLADEMAEMKTSITETRNEITQTVSKTLEDQSAIIQQIQRVQKD
TNDDLAALYMLKVQKTKNGIPYVAGIGAGIEDTDGQPLSNILLLADRIAMINPEDGNTTPLFVAQGNQLFMNDVFLKRLF
AVSITSSANPPTFSLTPEGRLTARNADISGNVNANSGTLNNVTINENCRVLGKLSANQIEGDLVKTVGKAFPRDSRAPER
WPSGTITVRVYDDQPFDRQIVIPAVAFSGAKHEREHTDIYSSCRLIVRKNGAEIYNRTALDNTLIYSGVIDMPAGHGHMT
LEFSVSAWLVNNWYPTASISDLLVVVMKKATAGISIS
>SEQF1516_EDU85002.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKITTGVSYTTSAVGTEYWLLQLLDKVSPSQWVAIGVLGSLLFGLLTYLTNLYFKIREDRRKVARGE
>SEQF1516_EDU85003.1 IS1203 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU85004.1 transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKA
EVIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU85005.1 hydrogenase-1 expression protein HyaE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNDTPFDALWQRMLARGWTPVSEFRLDDWLTQAPDGVVLLSSDPKRTPEVSDNPVMIGELLREFPDYTWQVAIADLEQS
EAIGDRFGVFRFPATLVFTGGNYRGVLNGIHPWAELINLMRGLVEPQQERAS
>SEQF1516_EDU85006.1 cytochrome bd-II oxidase, subunit I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAIMETIYVVTGKTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTN
WSFYSNYVGDIFGAPLAMEALMAFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNLSALWILNANGWMQYPTGAHFD
IDTLRMEMTSFSELVFNPVSQVKFVHTVMAGYVTGAMFIMAISAWYLLRGRERDVALRSFAIGSVFGTLAIIGTLQLGDS
SAYEVAQVQPVKLAAMEGEWQTEPAPAPFHVVAWPEQDQERNAFAIKIPVLLGILATHSLDKPVPGLKNLMAETYPRLQR
GRMAWLLMQEISQGNREPHVLQAFRELEGDLGYGMLLSRYAPDMNHVTAAQYQAAMRGAIPQVAPVFWSFRIMVGCGSLL
LLVMLIALVQTLRGKIDQHRWVLKMALWSLPLPWIAIEAGWFMTEFGRQPWAIQDILPTYSAHSALTTGQLAFSLIMIVG
LYTLFLIAEVYLMQKYARLGPSAMQSEQPTQQQG
>SEQF1516_EDU85007.1 bacteriophage lambda head decoration protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTKNITEQRAEVRIFAGNDPAHTATGSSGISSATPALTPLMLDEASGKLVVWDGQKAGSAVGILVLPLEGTETVLTYYK
SGTFATEAIRWPESVDEHKKANAFAGSALSHAALP
>SEQF1516_EDU85008.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTLFRKEYPRKSRATEFLFLILFIVLMTPISPLIFVWAIGKIIELVIELYNDVVWASFNTLHNKINPYKEN
>SEQF1516_EDU85009.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPIPVETDEEFHTLATSLSQKLEMMAAKAEANERDPA
>SEQF1516_EDU85010.1 major head protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGLFTTRQLLGYTEQKVKFRALFLELFFRRTVNFHTEEVMLDKITGKTPVAAYVSPVVEGKVLRHRGGETRVLRPGYVKP
KHEFPWSR
>SEQF1516_EDU85011.1 hypothetical protein ECH7EC4501_3804 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEMIMACSTFNPLTLQKYQPDPEDLCSLCGGNHGKAAMIECKDKIHICLNCVDVLVDIKNEREDKKRSEAVRALDSWMRD
GYSAAQIYDLAISKGEIPGVRIE
>SEQF1516_EDU85012.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSPSPPTENESKEKQKSRQCHPLTANSGSRDYGIQALLKMPDNIPASPDSGYK
>SEQF1516_EDU85013.1 group 4 capsule (G4C) polysaccharide, YmcB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKLQSYFIASVLYVMTPHAFAQGTVTIYLPGEQQTLSVGPVENVAQLVTQPQLRDRLWWPGALLTDSAVKAKALKDYQH
VMAQLASWEAEADDDVAATIKSVRQQLLNLNITGRLPVKLDPDFVRVDENSNPPLVGNYTLYTVQRPVTITLLGAVSGAG
QLPWQAGRSVTDYLQDHPRLAGADKNNVIVITPEGETVVAPVALWNKRHVEPPPGSQLWLGFSAHVLPEKYADLNDQIVS
VLTQRVPD
>SEQF1516_EDU85014.1 putative excisionase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRELVNQHNHGIQPVITPVVQINANEWVTLELLMAVTGLRKGTILRARDSAWMNGREYKQIAPDGTPKKNSECLYHLPTI
NTWIKNQPLPSQDV
>SEQF1516_EDU85015.1 IS66 family element, orf2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPS
ARDGKVFLTQAQLAMLLEGIDWRQPKRLLTSLTML
>SEQF1516_EDU85016.1 cold shock DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNKMTGLVKWFNADKGFGFITPDDGSKDVFVHFTAIQSNEFRTLNENQKVEFSIEQGQRGPAAANVVTL
>SEQF1516_EDU85017.1 4Fe-4S binding domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEKKRTRWQRRPGTTGGKLPWNDWHNATTWRKATQLLLLAMNIYIAITFWYWVRYYETAGSTIFVARPGGIEGWLPIAG
LMNLKYSLATGQLPSVHAAAMLLLVAFIVISLLLKKAFCSWLCPVGTLSELIGALGNKLFGRQCVLPRWLDIPLRGVKYL
LLSFFLYIALLMPAQAIHYFMLSPYSVVMDVKMLDFFRHMGTATLISVTVLLIASLFIRHAWCRYLCPYGALMGVVSLLS
PFKIRRNAESCIDCGKCAKNCPSRIPVDKLIQVRTVECTGCMTCVESCPVASTLTFSLQKPAANKKAFALSGWLMTLLVL
GIMFTVIGYAMYAGVWQSPVPEELYRRLIPQAPMIGH
>SEQF1516_EDU85018.1 asch domain superfamily [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANLQLAVKGEYFDAMIRGEKTEEYRLFNDYWNKRIMFREYDRLIITKGYPKRDDSSRRIDVPYDGYEIKTITHPHFGDK
PVKVFAIKVNIGNE
>SEQF1516_EDU85019.1 Int protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLDAGGTMANSAYPAGVENHGGKLRITFKYRGKRVRENLRVPDTPKNRKIAGELRASVCFAIRTGTFDYADRFPDSPNL
KLFGLVKKDITVGELAQKWLTLKAMEIGSNALNRYQSVMKNMLPRLGPGRLASSITKEDLLFIRKDLLTGEKGSRKTSTS
RKGRTVPTVNYYMTTTAGMFSFAAENGYLEKNPFNSITPLRKSKPVPDPLTRDEFSRLIDACHHQQTKNLWTVAVFTGMR
HGEIAALAWEDIDLKAGTITVRRNFTKIGDFTLPKTDAGTNRVIHLLAPAIEALKNQAMLTRLSRQHQITVQLREYGRTI
LHECTFVFCPQIVRKNHKAGINYAVSSIGATWDSAIKRAGIRSRKAYQSRHTYACWALSSGANPTFIASQMGHSSASMVY
NVYGAWMPECSVTQVAMLNNVLNARAPDVPQSDQEDEIKLYFSK
>SEQF1516_EDU85020.1 hydrogenase-1 operon protein HyaF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSETFFHLLGPRTQPNDDSFSMNPLPITCQVNDEPSMAALEQCAHSPQVIALLNELQHQLSQRQPPLGEVLAVDLLNLNA
DDRHFINTLLGEGEVSVRIQQADDSESEIQEAIFCGLWRVRRRRGEKLLEDKLEAGCAPLALWQAATQNLLPTDSLLPPP
IDGLMNGLPLAHELLAHVRNPDAQPHSINLTQLPISEADRLFLSRLCGPGNIQIRTIGYGESYINATGLRHVWHLRCTDT
LKGPLLESYEICPIPEVVLAAPEDLVDSAQRLSEVCQWLAEAAPT
>SEQF1516_EDU85021.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSDYLQTAILNLPSLNEITIKNKPRKNNKTTHKKKLNNKQK
>SEQF1516_EDU85022.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTKSHYFDFDIITFKPGHFFSRGEANFRDFFPCILVQLGDFLRDKVGDFRFGLFFNSSIFTVNLFWS
>SEQF1516_EDU85023.1 IS66 family element, transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQLDKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTL
TGRVYDPAVQRPLRQTRTRKPFPESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
DAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELRRSLLSGWVDACCRLLSPLEEALHGYVMT
DGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNAGSALAPAVWFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELY
RNGGITEAACWAHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWLREKMKT
LSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKNFLFFGSDHGGERGALLYSLIGTCKLNDVDP
ESYLRHVLGVIADWPVNRVSELLPWRIALPAE
>SEQF1516_EDU85024.1 minor tail protein H [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQPVGDLVIDLSLDAVRFDEQMSRVRRHFSGLDTDVRKTASAVEQGLSRQALAAQKAGISVGQYKAAMRTLPAQFTDIA
TQLAGGQNPWLILLQQGGQVKDSFGGMIPMFRGLAGAITLPMVGVTSLAVATGALVYAWYQGDSTLSAFNKTLVLSGNQS
GLTADRMLTLSRAGQAAGLTFNQARESLAALVNAGVRGGEQFDAINQSVARFASASGVEVDKVAEAFGKLTTDPTSGLIA
MVRQFRNVTAEQIAYVAQLQRSGDEAGALQAANDIATKGFDEQTRRLKENMGTLETWADKTGKAFKSMWDAILDIGRPES
SADMLASAQKAFDEADKKWQWYQSRSQRRGKTASFRANLQGAWNDRENARLGLAAATLQSDMEKAGELAARDRAERDASQ
LKYTGEAQKAYERLLTPLEKYTARQEELNKALKDGKILRADYNTLMAAAKKDYESTLKKPKSSGVKVSAGERQEDQAHAA
LLALETELRTLEKHSGANEKISQQRRDLWKAENQYAVLKEAATKRQLSEQEKFLLAHKDETLEYKRQLAELGDKVEHQKR
LNELAQQAVRFEEQQSAKQAAISAKARGLTDRQAQRESEAQRLRDVYGDNPAALAKATSALKNTWSAEEQLRGSWMAGLK
SGWGEWAESATDSFSQVKSAATQTFDGIAQNMAAMLTGAEADWRGFTRSVLSMLTEIFLKQAMVGIVGSIGSAIGGAFGG
GASASTGTAIQAAAANFHFATGGFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYAEGGYVGGAGSPAQMR
RAEGINFNQNNHVVIQNDGTNGQAGPQLMKAVYDMARKGAQDELRLQLRDGGMLSGSGR
>SEQF1516_EDU85025.1 phage tail assembly protein T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAGMTSTEYADWHRFYRTHYFQDTQLDMHFSGLTYAVLSLFFCDPDMHPSDFSLLVPRHEEEQVERPDEDKMLMQKAAG
LAGGVRFGGDGGRDILSSADVADVMVDDAALMMASAGIPGGVRYVPAGW
>SEQF1516_EDU85026.1 cytochrome c-type protein torC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTSTTEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDC
HIPPDIPGMVKRKLEASNDIYQTFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRAGANDSGDTLYSIDIKPIYAAKGDKEASGSLLPASEVKVLKRDG
DWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGDVQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAY
ADSLYNGTCNQCHGAPEISHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK
>SEQF1516_EDU85027.1 hypothetical protein ECH7EC4501_3743 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKGMESSVLDNAIASLLRAKIQNPVSISFPFDTSFFK
>SEQF1516_EDU85028.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLQELIDLTPEQEKAWNRLVKAVKDFRAAGGKFYSVLDTLSAYNGEHVASIDNDKGYHTASVYMPSIDAPGLTSWADD
WHGITLKDGVEVDKD
>SEQF1516_EDU85029.1 hypothetical protein ECH7EC4501_3818 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNIKKYIIDYDWKASIEIEIDHDVMTEEKLHQINNFWSDSEYRLNKHGSLLNAVLIMLAQHALLIAISSDLNAYGVVCE
FDWNDGNGQEGWPPMDGSEGIRITDIDTSGIFDSDDMTIKAA
>SEQF1516_EDU85030.1 low molecular weight protein-tyrosine-phosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQLKFNSILVVCTGNICRSPIGERLLRKRLPGVKVKSAGVHGLVKHPADATAADVAANHGVSLEGHAGRKLTAEMARNY
DLILAMESEHIAQVTAIAPEVRGKTMLFGQWLEQKEIPDPYRKSQDAFEHVYGMLERASQEWAKRLSR
>SEQF1516_EDU85031.1 cytochrome bd-II oxidase, subunit II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARDDDERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYA
AAFSGFYVAMILVLCSLFFRPLAFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLSTKRAALLVMLCFLLAGYWLWVGIDGFVLLAQDANGPS
NPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPLLTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSP
ISSLTLWDSTSSQLTLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY
>SEQF1516_EDU85032.1 phage minor tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTFRWKVKPDMEVNSQPSVREVRFGDGYSQRMAAGLNADLKTYRVTLSVTREEARHLEAFLAEHGGWKAFLWTPPYAWR
QIKVTCAAWSSRVRMLRVEFSAEFKQVVN
>SEQF1516_EDU85033.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLHGAGCLPVNSVPAPESAIIPYTYSLIAPPHRGIHHASFF
>SEQF1516_EDU85034.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIAASYTMHLYCDCLQCTDGKYKSPDFGEYIGTSWAGCAKEARKDGWRISKDKTRAFAPGHKILRSNKGE
>SEQF1516_EDU85035.1 nickel-dependent hydrogenase 1, large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVITNAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCT
GVHALASVYAIEDAIGIKVPDNANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSP
GYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVKIHAVFGGKNPHPNWIVGGMPCA
INIDESGAVGAVNMERLNLVQSIITRTADFINNVMIPDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLL
MPGGAVINGDFNNVLPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQERYSWIKA
PRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALNLPLSGIQSTLGRILCRAHEAQWAAGKLQYFFNKLMTNLKNG
NLATASTEKWEPTTWPTECRGVGFTEAPRGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIP
EQPLEILRTLHSFDPCLACSTHVLGDDGSELISVQVR
>SEQF1516_EDU85036.1 tail assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQTESAILAHARRCAPAESCGFVVRTPEGERYIPCVNISAEPEAYFRIAPEDWLRAEMQGEIVALVHSHPGGLPWLSEA
DRRLQIKSALSWWLVCRGEIHKFRCVPHLTGRLFEHGVTDCYTLFRDAYHLAGIDMPDFEREDDWWRNGQNLYLDNMEAT
GFYRISLPSAQPGDILLCCFGASVANHAAIYCGNGELLHHLPEQLSKRERYSEKWQRRTHSAWRHRHWHVSAFTGIYNDL
AAASACM
>SEQF1516_EDU85037.1 trimethylamine-N-oxide reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTSRRATAAQAATEAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELD
KYPSKMIAGLPDHVHNAARIRYPMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLVLQNSKTIVLWGSDLLKNQQANW
WCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTHEYLGREHVKHIAVNPQTDVPLQLALAHTLYSENLYDKNFLANYC
VGFEQFLPYLLGEKDGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLAAMLGQIGL
PGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIPIARFIDAILEPGKVINWNGKSVKLPPLKMC
IFAGTNPFHRHQQINRIIEGWRKLETVIAIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEA
RNDFDIFRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFDHPQMFVRHQAFREDPD
LEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGGPGSQTYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGK
EPVFINPQDASARGIRNGDVVRVFNARGQVLAGAVVSDRYAPGVARIHEGAWHDPDKGGEPGALCKYGNPNVLTIDIGTS
QLAQATSAHTTLVEIEKCNGTVEQVTAFNGPVEMVAQCEYVPASQVKL
>SEQF1516_EDU85038.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNDFCDKYFEYYLQVNGVGHMDRNITIENEVYARIVWAEKAKTR
>SEQF1516_EDU85039.1 hydrogenase 1 maturation peptidase HyaD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPESVEIVDGGTQGLNLLGYVESASHLLILDAIDYGLEPGTLRTYA
GERIPAYLSAKKMSLHQNSFSEVLALADIRGHLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQAALAQLAAWGIVP
QPANESRCLNYDCLSMENYEGVRLRQYRMTLEEQG
>SEQF1516_EDU85040.1 putative prophage Qin DNA packaging protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQRQFPDLTPRHLDHLKTLIAKGANQCARAGDKLPDLLDEYIRATTE
>SEQF1516_EDU85041.1 hypothetical protein ECH7EC4501_3766 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLGEKGELVFTVLGVLLCCETVKVLLRIALDILRGRPEKKN
>SEQF1516_EDU85042.1 cold shock DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRKMTGIVKTFDRKSGKGFIIPSDGRKEVQVHISAFTPRDAEVLIPGLRVEFCRVNGLRGPTAANVYLS
>SEQF1516_EDU85043.1 outer membrane lipoprotein, group 4 capsule (G4C) polysaccharide [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNIYPVTPGLIDQLRAKPIMSQANPELEQQIANYEYRIGIGDVLMVTVWDHPELTTPAGQYRSASDTGNWVNADGAIFY
PYIGRLKVAGKTLTQVRNEITARLDSVIESPQVDVSVAAFRSQKAYVTGEVSKSGQQPITNIPLTIMDAINAAGGLTADA
DWRNVVLTQNGVKTKVNLYALMQRGDLRQNKLLHPGDILFIPRNDDLKVFVMGEVGKQSTLKMDRSGMTLAEALGNAEGM
NQDVADATGIFVIRATQNKQNGKIANIYQLNAKDASAMILGTEFQLEPYDIVYVTTAPLARWNRVISLLVPTISGVHDLT
ETSRWIQTWPN
>SEQF1516_EDU85044.1 YjhS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFKHYDVVRAASPSDLAEKLTHKLKEGWQPYGGPVAITPYTLMQAVAIEGDPQVGPSSKPDWFYVVVLAGQSNGMAYGE
GLPLPDSYDAPDPRIKQLARRSTVTPGGESCTYNDIIPADHCLHDVQDMSTLNHPKADLSKGQYGCVGQGLHIAKKLLPY
IPNNAGILLVPCCRGGSAFTQGAEGTFSADTGASQDSARWGVGKPLYQDLIARTKAALQKNPKNVLLAVCWMQGEFDMSA
ATHAQQPALFTAMLTQFRADLSVFNAQCHGGSAADVPWICGDTTYYWKNTYATQYDTVYGGYKNRESEGVYFVPFMTDGN
GVNTATNAPAEDPDIPASGYYGAASRTNGNQVSSNRPTHFSSWARRSIIPDRLATAILNAAGRTSAFISGKAPEIKPSPG
GNTPSGPSADTSVRTISLLPAAGEAAAQGWSIKDGGIQLSDGVFKITRQSNKTWSLTHPVDDAITLLTQGGRLNCKFRLS
GALTNNQFGLGIYLYTDAPVPDGVAMTGTGNPFLMSYFTQTTDGRVNLMHHRKAGNTKLGEFGDYGNDWQTLELVFTAGS
ATVTPKLNGVAGPAFQVIKDSLTLGLNALTLTDVTKNAAYGVEIESLVLEINAPAA
>SEQF1516_EDU85045.1 exonuclease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAW
GKQYENDARTLFEFTSGVNVIESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQY
SMWVTRKDAWYFANYDPRMKREGLHYVVVERDEKYMASFDEMVPEFIEKMDEALAEIGFVFGEQWR
>SEQF1516_EDU85046.1 phage minor tail protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDIHEESLNESVKSEQSPRVVLREIDLTVQGGERYFFCNELNEKGEAVTWQGRQYQVYPIDGSGFEMNGKGSSARPSLT
VSNLFGLVTGMAEDLQSLVGATVVRRRVYARFLDAVNFVAGNPEADPEQELSDRWVVEQMSELTAMTASFVLATPTETDG
ALFPGRIMLANTCMWTYRSDECGYTGGAVADEFDKPTTDIRKDRCSKCMRGCEMRGMVANFGGFLSINKLSQ
>SEQF1516_EDU85047.1 enterobacterial Ail/Lom family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKLYAAILSAAICLTVSGAPAWASEQQATLSAGYLHVSTNAPGSDNLNGINVKYRYEFTDTLGLVTSFSYAGDRNRQIT
RYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
GAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF
>SEQF1516_EDU85048.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFPEYRDLISRLKNENPRFMSLFDKHNKLDHEIARKEGSDDRGYNAEVVRMKKQKLQLKDEMLKILQHESVKEV
>SEQF1516_EDU85049.1 YjhS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFKHYDVVRAASPSDLAEKLTHKLKEGWQPYGGPVAITPYTLMQAVAIEGEPQVGPSSEPDWYYVIVLAGQSNAMAYGE
GLPLPDSYDAPDPRIKQLARRSTVTPGGAACRYNDIIPADHCLHDVQDMSTLNHPRADLSKGQYGCVGQGLHIAKKLLPY
IPNNAGILLVPCCRGGSAFTQGAEGTFSESTGASQDSARWGVGKPLYQDLISRTKAALQKNPKNVLLAVCWMQGEFDMSA
ATHAQQPALFTAMLTQFRADLSVFNAQCHGGSAADVPWICGDTTYYWKNTYATQYDTVYGGYKNRESEGVYFVPFMTDGN
GVNTATNAPAEDPDIPASGYYGAASRTNGNQVSSNRPTHFSSWARRSIIPDRLATAILNAAGRTSAFISGKAPEIKPSPG
GNTPSGPSADTSVRTISLLPAAGEAAAQGWSIKDGGIQLSDGVFKITRQSNKTWSLTHPVDDAITLLTQGGRLNCKFRLS
GALTNNQFGLGIYLYTDAPVPDGVAMTGTGNPFLMSYFTQTTDGRVNLMHHRKAGNTKLGEFGDYGNDWQTLELVFTAGS
ATVTPKLNGVAGPAFQVIKDSLTLGLNALTLTDVTKNAAYGVEIESLVLEINAPASS
>SEQF1516_EDU85050.1 tail length tape measure protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLRELIIKISANSQSFQSEIQRASRMGSEYYRTLQNGGRQAAAAARDQRRALAELNSQLTEIRGSAVGMAGAFAGAFA
SGHLISLADEWSSVNARLKQASQSSDEFASSQKVLMDISQRTGTAFSDNAALFARSAASMREYGYSAGDVLKVTEAISTG
LKISGASTAEAGSVITQFSQALAQGVLRGEEFNSVNESGDRIVRALAAGMGVARKDLKAMADDGQLTADKVVPALISQLE
VLRDEYAAMPETVSDGITKVENAFMAWVGGANEASGVTKTLSGVLNGVAGQIDNVATAVGALVAVGVARYFGNMASGAMS
ATAGLVTAARNEVALAEAQFRGTQIATARARAAVYRAQQAVAAARGTEMQIAAEARLAATQERLNRNIAARSAAQNALNS
TTAVGSRLMSGALGLVGDVPGLVMLGAAAWYTLYQNQEQARESARQYALTIDEIAHKTPSMSLPEASDNEGRTRAALTEQ
NRLIDEQASRVKSLQEKAQSIQDVLAGLEDRRVALIRQQAAEQNKVYQSMLVMNGQHTEFNRLLGLGNELLQQRQGLVNV
PLRLPQATLDDKQQSALTKTERELALSRLKGEEKERARLGYAADDLGFVGDSYQEARQRYISNALEAWRNNEANKPKSRG
GKSETEKAEDSFSRLLKQQKAQLALAGQNTELAKLKYQTAQGELKTLTEIQKQELLRNAALIDQQKIREQLRSREETLKN
ENAAARASNDAELLGYGQGERARERMRELQQIRDSFRQKDADLQSQYQTGDISEDFYRQALAQNAQYLSERLKDQETFYA
ESDAQRADWQKGLQEGFSNWVDNASDYASQAAQLATEGISGMVNNITEMLNGNKVEWRSWASSVLQEISKVLMNAAIVNG
IKTAANGMSGAGGFLGSIGDWLGGAVANAKGGVYTSANLSAYSNSIVDTPTYFAFAKGAGLMGEAGPEAIMPLTRAADGS
LGVRAVGSMNGSAGLVYSPVYHIAIQNDGTNGQIGPEAAGSLVQLIDQRVQAVMLSMRRDGGMLSG
>SEQF1516_EDU85051.1 Gp14 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFDRVSPLGDERGDIRNAQIVKAVFGAQGMNVALKDAMLCWGEDEDKPEVDPFAALEDALSLAAMS
>SEQF1516_EDU85052.1 copper/zinc superoxide dismutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCALPPPLPIMFLSIGIINRSDRILHSYCAISSERCLLPCNQQAQSVNGINEGFMKCKIIAAIAMLTAASCGYAAEQEVP
MNLVSADGKEVSIGKITIQETPYGLLFTPALHSLSEGIHGFHVHEKGNCAPALKDGKPVAALSAGGHFDPKNTGKHLGPW
SPDGHLGDLPALFVTHDGKANYPVLAPRLNSLKEIKGRSLMLHAGGDNHHDHPEPLGGGGARMACGIIQ
>SEQF1516_EDU85053.1 TonB family C- domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRNLPLIILLSSLVMGCTQHKTDMPRQLVKALPQYPAYAAANYIKGRVDVKFDIGADGTVTRIEFIRSEPHHLFDEQVV
KAMAKWRFEKDRPRKGVKKTFIFSPSAP
>SEQF1516_EDU85054.1 pyruvate-flavodoxin oxidoreductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGLKNVWGDTPRVVEMQSEAGAIATVHGALQTGALSTSF
TSSQGLLLMIPTLYKLAGELTPFVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAANVQEAQDFALISHIATLKSR
VPFIHFFDGFRTSHEINKIVPLADDTILDLMPQAEIDAHRARALNPEHPVIRGTSANPDTYFQSREATNPWYNAVYDHVE
QAMNDFSAATGRQYQPFEYYGHPQAERVIILMGSAIGTCEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGSVRSV
AVLDRTKEPGAQAEPLYLDVMTALAEAFNNGERETLPRVIGGRYGLSSKEFGPDCVLAVFAELNAAKPKARFTVGIYDDV
TNLSLPLPENTLPNSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQGYFVYDSKKAGGLTVSHLRVSEQPIRSAYL
ISQADFVGCHQLQFIDKYQMAERLKPGGIFLLNTPYSTDEVWSRLPQEVQAVLNQKKARFYVINAAKIARECGLAARINT
VMQMAFFHLTQILPGDSALAELQGAIAKSYSSKGQDLVERNWQALALARESVEEVPLQPVNPHSANRPPVVSDAAPAFVK
TVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIPIWKEELCTQCNHCVAACPHSAIRAKVVPPEAMENAPAS
LHSLDVKSRDMRGQKYVLQVAPEDCTGCNLCVEVCPAKDRQNPEIKAINMMSRLEHVEEEKINYDFFLNLPEIDRSKLER
IDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLPSTPYTTDANGRGPAWANSLFEDNA
EFGLGFRLTVDQHRVRVLRLLDQFADKIPAELLTALKSDATPEVRREQVAALRQQLNDVAEAHELLRDADALVEKSIWLI
GGDGWAYDIGFGGLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMMMYGHVYVAQI
SLGAQLNQTVKAIQEAEAYPGPSLIIAYSPCEEHGYDLALSHDQMRQLTATGFWPLYRFDPRRADEGKLPLALDSRPPSE
ALEETLLHEQRFRRLNSQQPEVAEQLWKDAAADLQKRYDFLAQMAGKAEKSNTD
>SEQF1516_EDU85055.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSKNRTRRTTTRNIRFPNHMIEQINIALEHKGSGNFSAWVIEACRRRLATDATHLRPASMTNNEK
>SEQF1516_EDU85056.1 heat shock protein HslJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKVAAFVALSLLMAGCVSNDKIAVTPEQLQHHRFVLESVNGKPVTCDKNPPEISFGEKMMISGSMCNRFSGEGKLSNGE
LTAKGLAMTRMMCANPQLNELDNTISEMLKEGAQVDLTANQLTLATAKQTLTYKLADLMN
>SEQF1516_EDU85057.1 phage minor tail protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDIHEESLNESVKSEQSPRVVLWEIDLTVQGGERYFFCNELNEKGEAVTWQGRQYQAYPIDGSGFEMNGKGSSARPSLT
VSNLFGLVTGMAEDLQSLVGATVVRRRVYARFLDAVNFVAGNPEADPEQELSDRWVVEQMSQLTAMTASFVLATPTETDG
ALFPGRIMLANTCMWTYRSDECGYTGGAVADEFDNPTTDIRKDRCSKCMRGCEMRGMAVNFGGFLSINKLSQ
>SEQF1516_EDU85058.1 PAP2 family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQGAGWLLLLAPFFFFTYGSLNQFTAVQDFNSHDIPSQVFGWETAIPFLPWTIVPYWSLDLLYGFSLFVCSSTFEQRRL
VHRLILATVMACCGFFLYPLKFSFIRPEVSGVTGWLFSQLELFDLPYNQSPSLHIVLCWLLWRHFRQHLAVRWRKVCGGW
FLLIAISMLTTWQHHFIDVITGLAVGMLIDWMIPVDRRWNYQKPDQRRIKIALPYVVGACACIVLMELMMMVQLWWSVWL
CWPVLSLLIIGRGYGGLGAITTGKDSQGKLPPAVYWLTLPWRIGMWLSMRWFCRRLEPVSKMTAGVYLGAFPRHIPAQNA
VLDVTFEFPRGRATKDRLYFCVPMLDLVVPEEGELRQAVAMLETLREEQGSVLVHCALGLSRSALVVAAWLLCYGHCKTV
DEAISFIRARRSHIVLKEEHKAMLKLWENR
>SEQF1516_EDU85059.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNITPFPTLSTATIDAINVIGQWLAQDDFSGEVPYQADCVILAGNAVMPTIDAACKIARDQQIPLLISGGIGHSTTFLYS
AIAQHPHYNTIRTTGRAEATILADIAHQFWHIPHEKIWIEDQSTNCGENARFSIALLNQAVERVHTAIVVQDPTMQRRTM
ATFRRMTGDNPDVPRWLSYPGFVPQLGNNADSVIFINQLQGLWPVERYLSLLTGELPRLRDDSDGYGPRGRDFIVHVDFP
AEVIHAWQTLKHDAVLIEAMESRSLR
>SEQF1516_EDU85060.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNVENIIWHDGVLVETRMECHHTEYNFILTAELYVDEFTAGRERKRFEFTGVEHLSQVMDIAELIDNQNAGNIKDATIV
YKAKKYKISLHLFGGFLSFTFKTMRVIDNECA
>SEQF1516_EDU85061.1 HNH endonuclease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAELRTLQSRIKTLNTRRVNILKGEQRRVSGSARVSLKRHIWLRDAGQCCLCGRVVDLCDSELDHRIALQFGGGNEETNL
WTLCTECHRQKSAREAAGGMPDPTLPEVSGGSGRADDIIGL
>SEQF1516_EDU85062.1 universal stress protein F [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRTILVPIDISDSELTQRVISHVEAEAKIDDAEVHFLTVIPSLPYYASLGLAYSAELPAMDDLKAEAKSQLEEIIKKFK
LPTDRVHVHVEEGSPKDRILELAKKIPAHMIIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR
>SEQF1516_EDU85063.1 tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVKISGVLKDGTGKPVENCTIQLKARRTSSTVVVNTVASENPDEAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYED
SQPGTLNDFLGAMSEDDVRPEALRRFELMVEEAARHAEEAKKNAGEAETSARNAGISASQAEESAANADTSAGDASESAR
QAAESAAAAKQSEDASSSSASAAAQKASESSQSAAEAELSRKTAESAAGNAARDATTATEKARESAESAQSAEQSRIAAE
EAVNRIPTVVGPPGPKGEQGPAGPQGPKGDKGERGDTGPVGATGERGPAGDAGPAGPQGPKGDRGERGETGLTGNAGPQG
PKGDTGAAGPAGPQGPKGETGAAGPVGATGPQGPKGDPGETQIRFRLGPGNIIETNSNGWFPDTDGALITGLTFLAPKDA
TRVQGFFQHLQVRFGDGPWQDVKGLDEVGSDTGRTGE
>SEQF1516_EDU85064.1 tail assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQTESAILAHARRCAPAESCGFVVRTPEGERYIPCVNISAEPEAYFRIAPEDWLRAEMQGEIVALVHSHPGGLPWLSEA
DRRLQIKSALSWWLVCRGEIHKFRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIDMPDFEREDDWWRNGQNLYLDNMEAT
GFYRISLPSAQPGDILLCCFGASVPNHAAIYCGNGELLHHLPEQLSKRERYSEKWQRRTHSAWRHRHWHASAFTGIYNDL
AAASACM
>SEQF1516_EDU85065.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDERFINITPTSLSFKHADLSGLSYKNARLELALICPAIKSEVKISFDWIHSFRVTDEGDLLGMSGKQGINQTGIYRVAN
STYLTWFTMQSCEIHKNKMIEHYVIATSNDVIDVLSTVSPQIVYD
>SEQF1516_EDU85066.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENSRIPGEHFFTTSDNTALFYRHWPALQPGAKKVIVLFHRGHEHSGRLQHIVDELAMPDTAFYAWDARGHGQTSGPRGY
SPSLARSVRDVDEFVRFAASDSQVGLEEVVVIAQSVGAVLVATWVHDYAPAIRGLVLASPAFKVKLYVPLARPALALWHR
LRGLFFINSYVKGRYLTHDRQRVASFNNDPLITRAIAVNILLDLYKTSERIVSDAAAITLPTQLLISGDDYVVHRQPQID
FYHRLRSPLKELHLLPGFYHDTLGEENRAQAFEKMQSFISRLYANKSQKFDYQHEDRTGPSADRWRLLSGGPVPLSPVDL
AYRFMRKAMKLFGTHSAGLHLGMSTGFDSGSSLDYVYQNQPQGSNAFGRLIDKIYLNSVGWRGIRQRKTHLQILIKQAVA
DLHAKGLAVRVVDIAAGHGRYVLDALANEPAVSDILLRDYSELNVAQGQEMIAQRGMSGRVRFEQGDAFNPEELSALTPR
PTLAIVSGLYELFPGNEQVKNSLAGLANAIEPGGILLYTGQPWHPQLELIAGVLTSHKDGKPWVMRVRSQGEMDSLVRDA
GFDKCTQRIDEWGIFTVSMAVRRDN
>SEQF1516_EDU85067.1 tellurite resistance protein TehB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRNSLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNL
HTRVVDLNNLTFDGEYDFILSTVVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYY
EGWEMVKYNEDVGELHRTDANGNRIKLRFATMLARKK
>SEQF1516_EDU85068.1 ATP-dependent helicase HrpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEQQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQAIFQEMAKEIDQAAGKVLLREAARPEITYPDNLPVS
QKKQDILEAIRDHQVVIVAGETGSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRF
SDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLPRRPDLKIIITSATIDPERFSRH
FNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQAIFDAVDELSQESPGDILIFMSGEREIRDTADALNKLNLRHTEI
LPLYARLSNSEQNRVFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQASANQRKGRC
GRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAAFPFVEAPDKRNIQDGVRLLEELGAITTDEQ
ASAYKLTPLGRQLSQLPVDPRLARMVLEAQKHGCVREAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVN
LWNYLGEQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHIALLTGLLSHIGMKDAD
KQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGRIAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATE
KVTVYGLPIVAARKVNYSQIDPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEFYD
QRIGHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGNLKLRLSYQFEPGADADGVTVHIPL
PLLNQVEESGFEWQIPGLRRELVIALIKSLPKPVRRNFVPAPNYAEAFLGRVTPLELPLLDSLERELRRMTGVTVDREDW
HWDQVPDHLKITFRVVDDKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIWSFGQLPESYEQKRGNYKVKA
WPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPSPIKYLHEKLPNKAKLGLYFNPYGKVLELIDDCISCGVDQL
IDANGGPVWTEEGFAALHEKVRAELNDTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTG
NGFKRLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWFNKLPPARREDEDVKEIRWMIEELRVSYFAQQL
GTPYPISDKRILQAMEQISG
>SEQF1516_EDU85069.1 methyl-accepting chemotaxis protein III [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIQAGAASRIAEMEAMKRNIAQAESEIKQSQQGYRAYQNRPVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAI
INHESEQIRTLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLITFMVLRRIVIRPLQHAAQR
IEKIASGDLTMKDEPAGRNEIGRLSRHLQQMQHSLGMTVGTVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAAS
MEQLTATVKQNADNAHYASKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAVEAAR
AGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTMSTIVDAVASVTHIMQEIAAASDEQSR
GITQVSQAISEMDKVTQQNASLVEEASAAAVSLEEQAARLTEAVDVFRLNKQSVLAEPRGAGEPVSFAPV
>SEQF1516_EDU85070.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRTLLIAVWAIGLMSDSAMALTLNEARSQGRVGETLNGYLVALQTDAETQALVKDINEARNHSYQQLAKQNNVSTKEIA
KLAGQKLVARAKSGQYVQGVNGKWLRK
>SEQF1516_EDU85071.1 putative phage head-tail adaptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAISAGRLTQMISVLNPVLTRNAAGEMTEEWVSCGKIHADIRGRSSRERMQSGAEMAQAEIRIWVRGQSGREITAASRLH
VLSGPWRDRILNVVGLPVPDVTGGRLEILCRLGGEK
>SEQF1516_EDU85072.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVRNVKFDNLSFYEEKIRWRMRRQISNAEAIFYENQEEHIRRFLGRYTCRKPVLVYWESEQRWTSVNGLEVMSMFGEHC
HHIYLDDIKKKIQTELPENKTLDFKRQLQFIILGDDKIRIWVPEGKLYFALMNVLQMFPMKNG
>SEQF1516_EDU85073.1 FMN-dependent NADH-azoreductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLAANPIPVLDGELVGALRPSDAPLTTRQQEALALSDEL
IAELKAHDVIVIAAPMYNFNISTQLKNYFDLVARAGVTFRYTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTF
LGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVAA
>SEQF1516_EDU85074.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQMEKITTGVSYTTSAVGTGYWLLQLLDKVSPSQWVAIGVLGSLLFGLLTYLTNLYFKIREDRRKTARGD
>SEQF1516_EDU85075.1 Gp11 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEADLYPYLAHLAGGQVYPYVVPLLDGRPSVALPWVVFSLISSVSADVMGGQAESSVSVQIDVYAGTVTQARQIRQDAR
EAIMLLAPGSVSEMQDYIPENRCYRATLEFQVTV
>SEQF1516_EDU85076.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDAARLESGIRISIGSGQYSVHYVQLLDGFSVEPVRGGLLDRLLGREHRMERRAVALERQLNGGVDFLSSVNNYFQSVM
AEHRENKTSNKILMEKINSCLFRPDSNHFSCPESFLTCPITLDTPETGVFMRNSRGAEICSLYDKDALVQLVETGGAHPL
SREPITESMIMRKDECHFDTKREAFCCK
>SEQF1516_EDU85077.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLGKYKAVLALLLLIILVPLTLLMTLGLWVPTLAGIWLPLGTRIALDESPRITRKGLIIPDLRYLVGDCQLAHITNASLS
HPSRWLLNVGTVELDSACLAKLPQTEQSPAAPKTLAQWQSMLPNTWINIDKLIFSPWQEWQGKLSLALTSDIQQLRYQGE
KVKFQGQLKGQQLTVSELDVVAFENQPSVKLVGEFTMPLMPDGLPVSGHATATLNLPQEPSLVDAELDWQENSGQLIVLA
RDNGDPLLDLPWQITRQQLTVSDGRWSWPYAGFPLSGRLGVKVDNWQAGLENALVSGRLSVLTQGQAGKGNAVLNFGPGK
LSMDNSQLPLQLTGEAKQADLILYARLPAQLSGSLSDPTLTFEPGALLRSKGRVIDSLDIDEIRWPLAGVKVTQRGVDGR
LQAILQAHENELGDFVLHMDGLANDFLPDAGRWQWRYWGKGSFTPMNATWDVAGKGEWHDSTITLTDLSTGFDQLQYGTM
TVEKPRLILDKPVVWVRDAQHPSFSGALSLDAGQTLFTGGSVLPPSTLKFSVDGRDPTYFLFKGDLHAGEIGPVRVNGRW
DGIRLRGNAWWPKQSLTVFQPLVPPDWKMNLRDGELYAQVAFSAAPEQGFRAGGHGVLKGGSAWMPDNQVNGVDFVLPFR
FADGAWHLGTRGPVTLRIAEVINLVTAKNITADLQGRYPWTEEEPLLLTDVSVDVLGGNVLMKQLRMPQHDPALLRLNNL
SSSELVSAVNPKQFAMSGAFSGALPLWLNNEKWIVKDGWLANAGPMTLRLDKDTADAVAKDNMTAGTAINWLRYMEISRS
STRINLDNLGVLTMQANISGTSRVDGKSGTVNLNYHHEENIFTLWRSLRFGDNLQVWLEQNAQLPETGCPSGKECEEKQ
>SEQF1516_EDU85078.1 hypothetical protein ECH7EC4501_4120 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKYWRDEIADGFTKTGVLLWFLLSRMGDVCYSYLSLEFKLK
>SEQF1516_EDU85079.1 D-lactate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANGCEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFN
NVDLDAAKELGLKVVRVPAYDPEAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAML
RILKGFGMRLLAFDPYPSAAALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEAAFDQMKNGVMIVNTSRGALIDS
QAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVIQDDVFRRLSACHNVLFTGHQAFLTAEALTSISQTTLQNLSNLEK
GETCPNELV
>SEQF1516_EDU85080.1 phage tail assembly chaperone [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKDLKTLALARLSGFRHKTVKVPEWRNVSVVLREPSAEAWYLWQEVLNGDGEDDDTLSVVAKTRRNLEADVTLFCDVLC
DTDLQRVFTPDDREQVLAVYGPVHARLLRQALELIADAESARKK
>SEQF1516_EDU85081.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLALILFMGALVSFYADAGRKPCSGSKGGISHCTAGGKFVCNDGSISASKKTCTN
>SEQF1516_EDU85082.1 hypothetical protein ECH7EC4501_4110 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRIFTFLWLFFCPLFDQNIHYADVGDTKAKMQKKAIC
>SEQF1516_EDU85083.1 phage minor tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEIKTLHLVPREGMQVSEKPSVVRVRFGDGYEQRRPTGLNPQLKTFQAVFRVTDESTRRWLEEFLSWHGGYRAFLWRPP
KHNRTVRVVCREWSVTDNARYSDFSCTIEQVVN
>SEQF1516_EDU85084.1 phage lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAKIRYGLSAAVLALIAAGAPAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGATRVDGKPVIPGMKLSKEKCDRVNAI
ERDKALAWVEKNIRVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRINAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
VSRRDQESALACWGIDR
>SEQF1516_EDU85085.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIVIAAFASSFMLVGCTPRIEVAAPKEPITINMNVKIEHEIIIKADKDVEDLLKTRSDLF
>SEQF1516_EDU85086.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKKYELVVKEINNYPDKIAVTVALEIGGHPSLLLPHVAISLDRTEGATLEFYEAEAKKQAKQFFMDVAAGLCEGDGPLP
EKRPVILEAQDVLITYRGKLPGIITGSLKTPPLA
>SEQF1516_EDU85087.1 Ant [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEMISVDHEISMSSLDFLNNIINPARAEAGEVPHEPRKFLAKIEDELELDGTGKKFRLNNNQTRTAYYDLDFDQMMLVG
MRESKAVRRSVLARLKAMHGIQIPRTLPEALRFAAKLAEQKAVLENQLAIAAPKAEFVDNYVEASGLMGFREVAKLLGIK
ETDFRLFLLENGIMYRLAGKMTPYSHHLDAGRFSVKTGEAGNGHAFTQVKFTPKGVQWIAGLLAAWRATAA
>SEQF1516_EDU85088.1 TerB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFGIFKKKTRRAAAEIKKFEKRDLAQAVINAAYLVAYADGECEASEKAKIEQVLRNQPALSAFTSEINAISATIIGQLDT
NFKIGRRAALREIEDVKHDTREAEDVLDVAVAIAEADGEIEPEERKVLEEIAGVLGLRLENHL
>SEQF1516_EDU85089.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVDLTPYILPGVSFLSDIPQETLSEIRNQTIRGEAQIRLGELMVSIRPMQVNGYFMGSLNQDGLSNDNIQIGLQYIEHI
ERTLNHGSLTSREVTVLREIEMLENMDLLSNYQLEELLDKIEVCAFNVEHAQLQVPESLRTCPVTLCEPEDGVFMRNSMN
SNVCMLYDKMALIHLVKTRAAHPLSRESIAVSMIVGRDNCAFDPDRGNFVLKN
>SEQF1516_EDU85090.1 hypothetical protein ECH7EC4501_4116 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGARLISYRFLLWQKWDKRPQKGQKWGKKSVDYCALL
>SEQF1516_EDU85091.1 hypothetical protein ECH7EC4501_4149 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLHGELPQHEDDKNGLEIFAGLADSVFMGGCPVNYCY
>SEQF1516_EDU85092.1 oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLREALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLT
IVTKIGARRGEDASWLPAFSPAELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIG
LSNVTPTQVAEARKIAEIVCVQNEYNIAHRADDAMIEALARDGIAYVPFFPLGGFTPLQSSTLSDVAASLGATPMQVALA
WLLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEKVLSTLDGISRE
>SEQF1516_EDU85093.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKNSLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSKTLNELEQLTGARLFERGRQGAQLTLPGEQFLTHAVR
VLDAINTAGQSLHRKEGPNNDVVRVGALPTAALGILPSVIGQFHQQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSD
PELMTGLNYELLFLESLKLVVRPNHPLLQENVTLSRVLEWPVVVSPEGTAPRQHSDALVQSQGCKIPSGCIETLSASLSR
QLTVEYDYVWFVPSGAVKDDLRHATLVALPVPGHGAGEPIGILTRVDATFSSGCQLMINAIRKSMPF
>SEQF1516_EDU85094.1 aldehyde dehydrogenase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVPVQHPMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAEDARKAIDAAERAQPEWEALPAIERASWLRKISAGIR
ERASEISALIVEEGGKIQQLAEVEVAFTADYIDYMAEWARRYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIA
RKMAPALLTGNTIVIKPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAGNPKVAMVSMTGSVSAGEKIMAT
AAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDSRVINSGQVCNCAERVYVQKGIYDQFVNRLGEAMQAVQFGNPAER
NDIAMGPLINAAALERVEQKVARAVEEGARVALGGKAVEGKGYYYPPTLLLDVRQEMSIMHEETFGPVLPVVAFDTLEDA
ISMANDSDYGLTSSIYTQNLNVAMKAIKGLKFGETYINRENFEAMQGFHAGWRKSGIGGADGKHGLHEYLQTQVVYLQS
>SEQF1516_EDU85095.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTTQKRKFALALMSGKNKTASAIAAGYSAKTARVKGSQLAKDPEVLAFIARKQCETVEVDEVPVYRQKKSEQEDKPRRR
EAAAIPQPDENNPEMPPSAVMSPGIEYMEDGLPDPVKAMGRLLVENINTDPRLALDAAYKLAQFTHHKKGDAGKKSAKGD
AAKKAANRFAVPPPPRLVVNNDNEGNG
>SEQF1516_EDU85096.1 nickel-dependent hydrogenase, b-type cytochrome subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTENYVKAGNVMENKYSRLQISIHWLVFLLVIAAYCAMEFRGFFPRSDRPLINMIHVSCGISILVLMVVRLLLRLKYPT
PPIIPKPKPMMTGLAHLGHLVIYLLFIALPVIGLVMMYNRGNPWFAFGLTMPYASEANFERVDSLKSWHETLANLGYFVI
GLHAAAALAHHYFWKDNTLLRMMPRKRS
>SEQF1516_EDU85097.1 host specificity protein J [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKGGGRAHTPREAKDNLKSTQMMSVIDAIGEGPIEGPVKGLQSILVNKTPLTDTDGNPVIHGVTAVWRAGEQEQTPPEG
FESSGAETGLGVEVTKAKPVTRTITSANIDRLRVTFGVQSLVETTSKGDRNPTSVRLLIQLERGGKWMTEKDVTINGKTT
SQFLASVILDNLPPRPFNIRMVRETADSTTDQLQNKTLWSSYTEIIDVKQCYPNTAIVGLQVDAEQFGGQQMTVNYHIRG
RIIQVPSNYDPEKRTYSGIWDGSLKPAYSNNPAWCLWDMLTHPRYGMGKRLGAADVDKWALYAIAQYCDQTVPDGFGGTE
PRMTFNAYLSQQRKAWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDVVWPYTNSDVVVDDNGVGFRYSFSALKDRHTAVE
VNYTDPQNGWQTSTELVEDPEAILRYGRNLLKMDAFGCTSRGQAHRAGLWVIKTGLLETQTVDFTLGSQGLRHTPGDIIE
ICDNDYAGTMTGGRILSIDAASRTLTLDREVTLPETGAATVNLINGSGKPVSVAITAHPAPDRIQVSTLPDGVETYGVWG
LSLPSLRRRLFRCVSIRENTDGTFAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPPAVQHLTAEVTADSGEYQVLAR
WDTPKVVKGVSFLLRLTVAADDGSERLVSTARTTETTYRFTQLAPGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRI
ELTPGYFQITATPHLAVYDPTVQFEFWFSEKRIADIRQVETTARYLGTALYWIAASINIKPGHDYYFYIRSVNTVGKSAF
VEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLTEIRTSITDVSNEITQTVNKKLEDQSAAIQQIQKVQ
VDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIENTPDGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNEVFLKY
LTAPTITSGGNPPAFSLTPDGRLTAKNADISGSVNANSGALNNVTINQNCTIKGMLEATQVRGDFVKAVSKAFPKKVGTW
GNTETPNGTVTVTISDDHNFDRQIIIPPIIFNGIAYDDPGSGNNPGGTRYTGYGFEVRKNGVLIASRETKGAIPGSYSAV
IDMPSGGGSVTLEFKIFQKGNQGAGNITDCTVIVTKKAASGISIR
>SEQF1516_EDU85098.1 hypothetical protein ECH7EC4501_4075 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVLPEITVPPNAIASGRKSSNSFCANTVRDRSSRQRFCYHIVKIANGDNLP
>SEQF1516_EDU85099.1 CDP-alcohol phosphatidyltransferase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLYQIKPLFQSLLRPTMFWLYKHHVTANHITLAALALSLITGLLLMLVAQPILFLLLPIVLFIRMALNALDGMLARECN
QQTRLGAILNETGDVISDIALYLPFLFLPESNASLVILMLFCTILTEFCGLLAQTINGIRSYVGPFGKSDRALIFGLWGL
AVAIYPQWMQWNNLLWSIASILLLWTAINRCRSVLLMSAER
>SEQF1516_EDU85100.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSAFTVILLVVCGALSLGLNHYRDNVITYKAQRDKKARELELANATITDMQVRQRDVAALDAKYSRELADARAENETLR
ADVAAGRKRLRINATCSGTVREATGTSGVDNATVPRLADTAERDYFILRERLMTMQKQLEGAQDYIRTQCLN
>SEQF1516_EDU85101.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIGGSLSVARQLDGTAIGMCALPNGKRCSEQSLAAGSCGSY
>SEQF1516_EDU85102.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKIQYLQGTHDARAGDIRDVAQPCAEVLVRLGKAEYITARRPAGQKKKRDAEHGECGTFCGEPEKTRNQDVT
>SEQF1516_EDU85103.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKPRLCSWIGLLPLFMLSLPVQAELRCVANAVDIEPFFSAATAEDKQQVEQAINSSVNLVPFGLSASDWKVHRGDLVVE
GNIESNQKLIVLGNLTVKGNISTFSLSNPWVILGNVTATNIVTDSPLLITGSINASGLVFIDSYYDNPSTIKGSINARGI
FINDIIAPVVASSTNSEFMVRASDKNDTENVKKALMIINPDAYYWGLINDEDALKEIFKRSNIRMAGNVCNQMKKEALFR
LKPSPELVQELQMLDEGNVAAFEGRDIATFDLAIMRTLPRLKGISANLRKQLINSNDGQTIESMARYMPDNEILELTDQQ
LGYQPVVLGLLDREPLSVEIMTRMSHLPDGVGPLNLALRENLPLDIVMTLAKRDWDMIIQELYKDAWLLPESIIDGYIRS
DDSSIRQVGAGGQLTYNQAMQLANDSSNDVVTSLALKLAEMKHHGQLLRMTPQESDKIAVYLYQKFENDDDLIGALFLAL
PDNLQFNFVKRMEKKSPAYFCCRDMQIIHSDAALQRLLTRFNDPEGWSNLAKNQYLSTSMKQKIWQRALSHRKNNPKADS
DAYETSADMILSELISYGEVDDQMLLNATSLIRSDDWDFLESALISWDNLPAVVLKELQQNTPRNDIWAKFFLRQENSSR
AQVNEALRVYYALDPDALAQLDVLAKQPDRIWWSTLAKSNLTFFKFGALNNRHTPPAVLAAEIDPEWWIVAMNNPRFPVD
VLKARLKRDPLLALKLVNPELDLVRQLALNGKTRAIREQAMRKLDELY
>SEQF1516_EDU85104.1 peptidase U35, phage prohead HK97 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLKRACSLLTVKSFSEDERVITGIASTPSPDRDGDILEPEGAEFGSAIPFLWQHDHSRPVGQCTVRRVSEGLEITATLV
KPVPDMPSQLAARLDEVWAAIKTGLVRGLSVGFRPHEYTFLDGGGLHFLRWELMEVSAVTVPANAECTIRTIKSYDRPFS
AASGNRKPVVKIASSAGAAAQSTTVFHKEKTIMNIGEQIKSFENKRAALAASLEEVMTKAAEEGRTLDVEEEEHYDNTAA
EIRQVDAHLKRLRELEAGKAATAQPVKQAGNGNVAAVASAPVIRVEQKLDKGIGFARFAKSLAAAKGVRSEALEVARRQY
PDDSRLHHVLKSAVGAGTTTDPQWAGSLSEYQEYAQDFIDYLRPQTIIGRFGQGGIPALRQVPFNIRVHAQVSGGAAGWV
GEGKAKPLTKFDFESITFSHAKVSAIAVLTEELIRFSSPAADALVRNALAEAVVARLDTDFVDPKKAAVADVSPASITHD
VKGTASTGNPDADAEAAFGQFVAANLQPTGAVWLMSSTNALALSMRKNALGQKEYPDMTLLGGSFQGLPVIVSQYVGDQL
VLVNAPDIYLADDGGVAVDMSREASLEMQSEPTGDSTTPSPVELVSMFQTGSVAIRAERWINWRRRRTAAVAVITGVNYG
SASGG
>SEQF1516_EDU85105.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDKLIMLAKGLCVIVGISFSLMLVVLFLSITWMALTSAGLVG
>SEQF1516_EDU85106.1 hypothetical protein ECH7EC4501_4100 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVFRENNEYTKGKDAFPFCFFFNGMECICLSPGFAAG
>SEQF1516_EDU85107.1 phosphatidate cytidylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLEKSLATLFALLILATLINRFRVWRLPERKGDEVTLRIRTWWGIVICFSLVISGPRWMTLTFFALISFLALKEYCTLIS
VHFPRWLYWVIPLNYLLIGFSCFELFLLFIPLAGFLILTTWRVLVGDTSGFLHTVSAIFWGWIMTVFALSHAAWLLMLTT
TNTQGGALLVLFLLALTESNDIAQYLWGKSCGRRKVVPKVSPGKTLEGLVGGVITTMIASLIIGPLLTPLNTLQALLAGL
LIGISGFCGDVVMSAVKRDVGVKDSGKLLPGHGGLLDRIDSLIFTAPVFFYFIRYCCY
>SEQF1516_EDU85108.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANSITADEIREQFSQAMSAMYQQEVPQYGTLLELVADVNLAVLENNPQLHEKMVNADELARLNVERHGAIRVGTAQELA
TLRRMFAIMGMYPVSYYDLSQAGVPVHSTAFRPIDDASLARNPFRVFTSLLRLELIENEILRQKAAEILRQRDIFTPRCR
QLLEEYDQRGGFNETQAQEFVQEALETFRWHQSATVDEETYRALHNEHRLIADVVCFPGCHINHLTPRTLDIDRVQSMMP
ECGIEPKILIEGPPRREVPILLRQTSFKALEETVLFAGQKQGTHTARFGEIEQRGVALTPKGRQLYDDLLRNAGTGQDNL
THQMHLQETFRTFPDSEFLMRQQGLAWFRYRLTPSGEAHRQAIHPGDDPQPLIERGWVAAQPITYEDFLPVSAAGIFQSN
LGNETQARSHGNASREAFEQALGCPVLDEFQLYQEAEERSKRRCGLL
>SEQF1516_EDU85109.1 tellurite resistance protein TehA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTYYNRSKFCGSGYARENSIKCISNILYKLNKMSKKMQSDKVLNLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGL
VILAMIIWGLLTSAFITRLIRFPHSVLAEVRHPVLSSFVSLFPATTMLVAIGFVPWFRPLAVCLFSFGVVVQLAYAAWQT
AGLWRGSHPEEATTPGLYLPTVANNFISAMACGALGYTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQ
LAPALVACSAWLSVNGGEGDTLAKMLFGYGLLQLLFMLRLMPWYLSQPFNASFWSFSFGVSALATTGLHLGSGSDNGFFH
TLAVPLFIFTNFIIAILLIRTLALLMQGKLLVRTERAVLMKAEDKE
>SEQF1516_EDU85110.1 phage protein, HK97 gp10 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIETLLDFSGLEDISRDLQLLSGAENNRVLREATRAGANVLKEEVVSRAPVRRGKLRRNVVVLSRRSRDGGMESGVHIRG
VNPDTGNSDNTMKADNPRNAFYWRFVEMGTVNMPPHPFVRPAFDVRSEQAAQVAIARMNRAIDEVLRR
>SEQF1516_EDU85111.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTALLTLEEIKAHLRVDHDADDDMLMDKVRQATAVLLAYIQGSRDKVIREDGELIPGEALTRMKGAAMRLTGMLYRNPDL
AEREDLVQGELPFSVSVLIYDLRCPTVL
>SEQF1516_EDU85112.1 putative phage terminase, large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWSTACPDWAERLKKGLSIIPAPIYPDQAAHALAIFKQLRIVDAPGSPTFGESCAPWVFDLVAALFGSYDAQTGVRHIKE
VFILIPKKNSKSTLAAGIMMTALLLNWRQAAGYTILAPTVEVAANAFNPARDMVRRDDDLDDLCQVQTHIRTITHRVTDT
TLKVVAADPNTVSGIKSVGTLIDELWLFGKQYKAEDMLREAIGGLASRPEGFVVYTTTQSNEPPAGVFRQKLQYARDVRD
GKIHDPHFLPVIFEHPPEMVESGAHLLMENLAMVNPNLGYSVDEAFLYREYRKAREAGEEAFRGFMSKHANVEIGLALRS
DRWAGADFWEQQGRRVSLDDILQRADVVTVGIDGGGLDDLLGMYVTGRDRETREWLGWGHAWAHETAVVRRKSEASRFQD
FVACGDMTIVRRVGDDTAEVAEYVRRIHEAELLDHIGIDPSGVGQILDSLAEAGIPDESVVGISQGWKLGGAIKTTERKL
AEGVLIHGDQPLMAWCVGNARVEPKGNAILITKQASGRGKIDPLMALFNAVSLMSLNPEPKKKEYAVFFI
>SEQF1516_EDU85113.1 bacteriophage lambda tail assembly protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTAAEAIRALSLQVPGFRRQMNEGWYQIRIAGDDTAPEAVYARLHEQLGEGTVIHIVPRLAGAGKGGLQIVLGAAAIVG
SFFTAGASMAAWGAALSAGGFSATTMLFSLGASMILGGVAQMLAPKPKTPEYRATDNGKQNTYFSSLDNMIAQGNPMPVP
YGEMLVGSRRISQDISTRDEGGGGKVVVIGRQA
>SEQF1516_EDU85114.1 periplasmic glucan biosynthesis protein, MdoG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAVCGTSGIASLFSQAAFAADSDIADGQTQRFDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSL
WHNVENRQLDAQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAGFRVFKAPELARR
DVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFWFDTVKPGATTFTVYALLDSASITGAYKFTIHCEK
SQVIMDVENHLYARKDIKQLGIAPMTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDN
NPKGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVCFWQPEKAVKAGDEFAFQYRL
YWSAQPPVHCPLARVMATRTGMGGFPEGWAPGEHYPEKWARRFAVDFVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIE
PIDGYRIQFDWYPTSDSTDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS
>SEQF1516_EDU85115.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVKLRLAVAALLLFLVVMVDFTSRIMSVLADGVLVCGIVVLLWPVIKRNSLHNA
>SEQF1516_EDU85116.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLTSDIRSHSFNLGVEVVRARIVANGRGDITVGGETVSIVYDSTNGRFSSSGGNGGLLSELLLLGFNSGPRALGERMLS
MLSDSGEAQSQESIQNKISQCKFSVCPERLQCPLEAIQCPITLEQPEKGIFVKNSDGSDVCTLFDAAAFSRLVGEGLPHP
LTREPITASIIVKHEECIYDDTRGNFVIKGN
>SEQF1516_EDU85117.1 glyceraldehyde-3-phosphate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYLLKHDSNYGPFPWSVDFTEDSLIVDGKSIAVYAEKEA
KNIPWKAKGAEIIVECTGFYTSAEKSQAHLDAGAKKVLISAPAGEMKTIVYKVNDDTLDGNDTIVSVASCTTNCLAPMAK
ALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLVIPELSGKLKGHAQRVPVKTGSV
TELVSILGKKVTAEEVNNALKQATTNNESFGYTDEEIVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFV
TQLIRTLEKFAKL
>SEQF1516_EDU85118.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRDIVRVFFRGSGIRMQKIPLLDWFYAINQDDNLLIFY
>SEQF1516_EDU85119.1 site-specific recombinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNVIPLQNSPERVFLLPIAPGVDFATALSLRRMATSTGATPAYLLAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEAR
MLTPESFDLDGARPFVRILSEKVRARRGRPPKDEVRLVPLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAV
RRAEADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHRDPRSMEVYTRVFALDMAATLAVPFTGDGRDAAEILR
TLPPLR
>SEQF1516_EDU85120.1 nuclease homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKYIPLVLFIFSWPVLCADIHGRVVRVLDGDTIEVMDSRKAVRIRLVNIDAPEKKQDYGRWSTDMMKSLVAGKTVTVTY
FQRDRYGRMLGQVYAPDGMNVNQFMVRAGAAWVYEQYNTDPVLPVLQNEARQQKRGLWSDADPVPPWIWRHRK
>SEQF1516_EDU85121.1 CopG family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQMKNNTAQATKVITAHVPLPMADKVDQMAARLERSRGWVIKQALSAWLAQEEERNRLTLEALDDVTSGQVIDHQAVQAW
ADSLSTDNPLPVPR
>SEQF1516_EDU85122.1 toxin B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIHPGSSLDKAINNTRVKNVSTDVKHGQIQERKRNFIYKKNDDISSRFKLYSSLVKQKNATEDVVLIGKMILDEVRSYRT
IHNDRNIVSNSGNWKTSFLCNLARLLYSIFNGSNYFCSREGENNSSPSSTLLTIHQPEKQELLQQKSIKHLPTSNNIDGY
IKIRKTRGAEDQTTTITQSLIINELLNGVDRNTIPFQKISELNDIIHSYENMQIKNSRKGIEILVKQGELLSSLINDNKG
NKQLSDNASKIINLLGIEYQSHKVDIEPFIHAVWVAGAPPDNTFSYITAFLNTYKDYTYLLWIDPNAFGAAKFSGILKNI
AMNYAIMRLRRTNPHLAEEMNEVILKIQNIQNETIEFKETRERLKELENRYKSLTSETKEKFNVFFLESMIGMQDNYFTY
CISNGISNTDDISRLDFLTNVLKLSPEVQNDFKSTVEKNKRDIDLLKNTISQKFGDRFQLRDINTLESFKKPQDYFFYQQ
EMLLRWNYAAASDQVRINILKEYGGIYTDTDILPAYSDKVSQIINEKSDDKRFFEDLKLRRIISESILSLIKGEKYSIKH
DGLDETTLNQLNNILSEIEKLTIDDYFKPVETKVVRDTFKIFKRYQKWTENTWNIRGNNNFMLTHKGSKCIDFILSGQKK
QYLELQRIRDNISYNNLFYTTEDLKSLNNVAIGGIPAKKYLEHGLFSEYRQDGTIPYVVSTLNISGPDMIMRQMKKYYKS
LGRIGEVHIKDNKLSDVNFLGVYASSNKDNKSFNWLNPVSVGINDITPDDESSWAVRNNDINKILFEKINCHVPEKLPTS
LYYEIDSRSFFQGWDNKSIKHVTEINKDLIKDINLLLTSSNIDVKLLIKLDRELYAISSKIDNPLALRSIRTLQLQLANY
VTSNTFEPENTINFIYDFYRKKQDDLLSAIKLFSRNDADTKIIVWYNSVMEKNVFLREVISCVLRSKKVDSYINENKKNL
SKEDAGALRDYAKLKMKELFSMLDDDGYKKIITTNAYIKERDKLSGIIYNIENSIISGHESFDIIRSNQHEWGDLSTVEQ
FKKFEFYVKSELSSAKSIFDDIKNKYITDPETKRNVLYHQLDSDIKERIAFLDISHYAYPGSLLEKLQLSGYVFSDINII
AEYLLASYGVSGHYSHGVVYPAPSDKLLELLRRHTKSNSEWIEKITPYVYDILSDNVSNVLRPPLSEEQKKILNDIKLEI
SKSVSEQYFMKLTEQKSSVIGIKYSVDFDRYNENLFLSLPINQNLTLPFMYRYFEMLYDIHIGIIENKANREFIYSKFSS
LNLDFLINDERVLNLEGLIKKYKYLSLSEIHRTLTNSTSFADISIPLLQTICPSITTIIKKTEYYGHQLTNAMTVASVVK
PYDFSNLGAINSIDKSVSDVPALHTIVEQAKYNLLSWNDFYNTHASIWDTIARQHKSTNIEFHPQSLLFDRDSKGKCLGL
SLLYLDTGGYGGGYQKLRHNIDTASTLYQTKYNDNLKLSNRDDFFLRKTQRIITMSNELGNNRLKNAQLEVLELKDPILT
EGILYQRRISSLLITTEYHSLALQQISSFWRVTDPNFGHCDFHSLAQALTFIKNITSNRNFSSLYGSGIVKIYFSESLNN
WKYIKLPLVQTGSLLRDIYLTTPEKLSTSGGSLNIMGHLVPVSFIYDIGGVINGNRISESTDVKNKIRSLKINGDILQHY
INTHYLSEEQTQKIKDIVDFLGIQDNTIKVKLESDIKPISEIQQPLHSILSRQKEHVKNLLSGLLDEFSNKLRKQGLSLK
TNVLSVNNFKESKINSDTVEVTVTDLQGRLYRVDIDTRVIGLTFKEGINSLSEALEHMNIDAIMSVIGLVQYARMIKMND
NISAIDHAGAVSDIKNIVDKFLGGILTLTNNRVYNPGGVSGASLEGFISSGLEVCASRMGGTAGRYLSNVAKVIKLPLLD
IGINIWSLYDSSLNHAKATTQIEYISTAIDVSFSSINTALSIGAIAYPPLAIAIVPITIFSHEVKNYAVYVNQINERHKL
WLEAEKYLDNGSAKVLSINKATGIIDLSNNQVLGNIYLDMRENPPILHGEKSYNSGKNIGSHPDMTDREIMESRAYNFAC
TKLSDAGEPDIFGWGDKEICNSMELSESQLANGYSNRQWPSQIPVIPEGIYNTVYLGYGETLRANTEVTLSSTGYFYEIA
RAYTDDELSEPLLTVCNQHSHVIGGKEPLTIIIPAIEHGMLGSNLHMIERFKNYNFSISGGKGGIKLMVGGIGDYNIECT
PGVRNIISFEQLSRDFNLDLDLSDGRKQNFNFHHPSGFYSGKVMSITQKGINAVVGTKLGYDKIRGNNLDNTFSLGSGGG
VIYSGGGSNTYFVPATLQDNLHIYISEKSNGNHIILGDMHSRLSIECHFSNNEREFIKMGYYNGCDVILESDTIQKIKSF
AKNITIQTADGVMANWDDKLNTLSVYSIDMIAWRDKNKTAKEPLPVDVIQLTNWRMHNTCSLFYDKYQVDIEANKLTYTV
LFPDTELPVQLNYTSIIYGNHGAKYTFLNSGSKTIDIHILDKNSDYDTFDFRNIIFEHYTNEIFISFDNQGGFVISILNN
ATSEAANINVFRKNMTSLDSSGSLIYLPSGDIYHISDIYKMSRGRKSFKLNVEKKPDIDDIINVAILETSYLQIKKIPNN
DDSDYILCLDNPNLSSYTLNFNDLSGYISSLWDNIRGSFTPFHKNTVNIAPNEKKYISLIGLDKLSFNIDVFRQALEVKN
KNSYKISKFTWETYGDIVVSPEDRISHLELDGFNYFSQPELDTPISDSFSYLYDNFQIVDSDVHIKLLHLNRETKQITPH
RIILKRYFIDSFAKTSITDREKNIYPVICDSPDHFTSDIYRHPFRIVLGNKTLYPSEELVKFISTSKEYLSNMDVINNVI
VPQKTTKKNKLSIVSLNSNIKNDIVLSGVMTGTSKIFHLNNSGDLLLTTSKTHGGGVVVIFKDFINNWWKYNLTLITVPI
DNKLSDNRINITPMGIKIQETVSGNDRLFFYPTPLKNGCFILHNPLYSNSFPSLYSHELFDLIEAYRNPTYSYLQNNIIN
RYIHTVSEYAGKDGIANMSLSIYAYSTCRFWSKESVAVGDTIKLSNYEHIEFSFNSFSKDYFREQNSDIYKIFFKIASSS
NSVVVDKNTLTQKNFLENNTFFSITGIDESLYEKHIIFITLKVIVPSKK
>SEQF1516_EDU85123.1 hypothetical protein ECH7EC4501_5181 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNNAVKIGRTILTAWIKQVPDLLFSYLHLTLSGVFLLLFLRSHYLSAG
>SEQF1516_EDU85124.1 IS1 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFQLTYRYEARKPGVQDQITEMPFNGAGVRDTARTLKIGINTVIRTLKNARHEE
>SEQF1516_EDU85125.1 ParB-like partition protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVTESKAKTERKSSRKPAKTQETVLSALLAQTEEVSVPLASLIKSPLNVRTVPYSAESVSELADSIKGVGLLQNLVVHA
LPGDRYGVAAGGRRLAALNMLAERDIIPADWPVRVKVIPQELATAASMTENGHRRDMHPAEQIAGFRAMAQEGKTPAQIG
DLLGYSPRHVQRMLKLADLAPVILDALAEDRITTEHCQALALENDTARQVQVFEAACQSGWGGKPEVQTIRRLVTESEVA
VAGNSKFRFVGADTFSPDELRTDLFSDDEGGYVDCVALDAALLEKLQAVAEHLREAEGWEWCAGRMEPVGFCREDAGTYR
SLPEPEAVLTEAEEERLNELMARYDALENQCEESDLLEAEMKLMRCMAKVRAWTPEMRAGSGVVVSWRYGNVCVQRGVQL
RSEDDVADNDYRTEQVQEKASVEEISLPLLTKMSSERTLAVQAALMQQSDKSLALLAWTLCLNVFGSGAYSNPARIRLEC
EHYSLTSDAPSGKEGAAFMAMMAEKARLAALLPDGWARDMTTFLSLSQEVLLSLLSFCTACSIHGVQTREYGHTSRSPLD
TLESAIGFHMRDWWQPTKANFFGHLKKPQIIAALNEAGLSGAARDAEKMKKGDAAEHAEHHMKDNRWVPGWMCAPRPQTD
ATERTDNLADAA
>SEQF1516_EDU85126.1 protein TraI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANSVWTVTAVSGDSVTLSGGQQTRVIRPAQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGSRKLMAGFESAYVAL
SRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVFEPKPDREVMNAERLFSTARELRDVAAGRAVLRQAGLAGGDSPARFI
APGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVRIAR
DNPDSGVVVRIAGEGRPWNPGAITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEIVRKMAENK
PDLPDGRTEQAVREIAGQERERAVTSEREAALPESVLREPQREREAVREVVRENLLQERLQQMERDMVRDLQKEKTLGGD
>SEQF1516_EDU85127.1 plasmid SOS inhibition protein PsiB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTELTLNVLHTMNAQEYEDIRAAGSDARRELTHAVMRELDAPDNWTMNGEYGSEFGGFFPVQVRFTPAHERFHLALCSP
GDVSQVWVLVLVNAGGEPFAVVQVQRRFAPEAVSHSLALAASLDTQGYSVNDIIHILMAEGGQV
>SEQF1516_EDU85128.1 replication regulatory protein repA2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQTENAVTSSSGAKRAYRKGNPLSDAEKQRLSVARKRASFKEVKVFLEPKYKAMLMQMCHEDGLTQAEVLTALIKSEAQ
KRCV
>SEQF1516_EDU85129.1 IncFII replication initiation protein RepA1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDLQQTYYRQVKNPNPVFTPREGAGTLKFCEKLMEKAVGFTSRFDFAIHVAHARSKGLRRRMPPVLRRRAIDALLQGLC
FHYDPLANRVQCSITTLAIECGLATESAAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTPALFAALDV
SEDAVAAARRSRVEWENRLRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIKRARARRDAGRERQDIVTLVKRQ
LTREISEGRFTANREAVKREVERRVKERMILSRNRNYSRLATASP
>SEQF1516_EDU85130.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHSQLKERIRLMRARLDNAAPVAEIRAESQLFVTPAPVCDRLVTLAEISNRDHILEPSAGTGAILRAIRDTAPEAMCDAV
EINSGLVRYLRENFNGVRVQCGDFMEWQPVQYYSRVIINPPFSHGQDIRHILRAFSLLRPGGVLVAVCLNGPRQQEKLLP
FSDVREELPRGTFAYTDVPTMIIRLRA
>SEQF1516_EDU85131.1 hypothetical protein ECH7EC4501_5142 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITFRVWHFEDSTVQLMNLTRVQIFLLSITCPYLLKVDISLKSC
>SEQF1516_EDU85132.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEYFRILQGLPDGPFTRKHAEAVAAQYRNVFIENDHGEQFRLVVRNNGAMVWRTWNFEDGAGYWMNHVIRDFGIIK
>SEQF1516_EDU85133.1 hydrolase, alpha/beta fold family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKITDHKLSEGIALTFRVPEGNIKHPLIILCHGFCGIRNVLLPCFANAFTEAGFATITFDYRGFGESDGERGRLVPAMQT
EDIISVINWAEKQECIDNQRIGLWGTSLGGGHVFSAAAQDQRVKCIVSQLAFADGDVLVTGEMNESERASFLSTLNKMAE
KKKNTGKEMFVGVTRVLSDDESKVFFEKIKARHPEMDIKIPFLTVMETLQYKPAESAASVQCPVLVVIAGQDSVNPPEQG
RALYDAVASGTKELYEEADACHYDIYEGAFFERVVAVQTQWFKQYL
>SEQF1516_EDU85134.1 general secretion pathway protein K [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLREQGVALLVVLLILSLMVTIAAVIAERNGRTFLRTVAQLDQLQAKWDGYTAETIAKQILQRSRQESPRKTHLAQNWA
QSERQFETRGGDVRGQIVDAQACFNLNAINYGVVDLTSIPYAARIFQQLLINLQVELLQARQVTAALRDWIDRDDKPVRG
GAEDEVYMGMEPPYLAANQPMQDVSELRLIRGIDARLYRKLLPYVCVLPTSDLSVNVNTLLDSQAPLLAALFLTKPDSLP
VTELLQRRPRTGWESVAAFLDAPPLKDIDTSAAMPVLAVSSNYFLVRLHVRSGEHLFSQQTLMQWREERFRIIQRQYGLT
MREVP
>SEQF1516_EDU85135.1 single-strand binding protein family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVRGINKVILVGRLGKDPEVRYIPNGGAVANLQVATSESWRDKQTGEMREQTEWHRVVLFGKLAEVAGEYLRKGAQVYI
EGQLRTRSWEDNGITRYVTEILVKTTGTMQMLVRAAGAQTQPEEGQQFSGQPQPQPPEGDDYGFSDDIPF
>SEQF1516_EDU85136.1 polysaccharide deacetylase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNARHLPVLMYHHVSRCPGLVTLSPETFCEQMKWLADNNWRTVTSAELEYFYQGGTLPRKSVMLTFDDGYLDNWLRAWP
VLKEYNLHAHIFLITGLIGKGNVRSRQEQEYSHRDCERLIADNRSDEVMLRWSEVREMRDSGLVEFHVHTHSHKRWDRLS
VSRAEQCRLMKEDILVGKQCLTEKLGFCSSHLCWPEGYYNRDYINLAGKLGFSYLYTTERRMNCPENGSLRIGRISTKER
EHSGWLKRRLFYYTTPLFSSVLALHKGPRLPDN
>SEQF1516_EDU85137.1 fertility inhibition protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEQKRPVLTLKRKTEGETPVRSRKTIINVTTPPKWKVKKQKLAEKAAREAELAAKKAQARQALSIYLNLPTQDEAVNTL
KPWWPGLFDGDTPRLLACGIRDVLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEEA
YAAARLDKIRRQNRIKAELQAVLDEK
>SEQF1516_EDU85138.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRQERVLRIKAFRRALELGGGERADGCRHFPRWKTELRNFPHSSCDLASNTLAYYLKERERCHPCIIFMEGNAGFHEAEN
STVHGHVIVLLDGEYIDLTLDQFDEYPDYIPYEPVESDGQIGKLLRNIMKHEDPVKTRQIDLDGGEELYAWLRDTADEVL
AADPEWQARERSIEEAREAAITVFPFLSDVQKTECEQGPDSQEAAR
>SEQF1516_EDU85139.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNGFRNSSRNGQVWRYQRAGSRAVILEVSGRWMEAAEAWRRAAGVAPRTDWQQFARKRAEHCHRRCRGRG
>SEQF1516_EDU85140.1 IS91, Orf2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDVRNKKLVFWFVRVDDEGYPEIARCTEREFATILAGISAGGMYCPECGTVHWPDGVPPPF
>SEQF1516_EDU85141.1 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIRTEFIPRFNLTLCFPRYWMTWTGIGIICVFAMVPPALRDPLLGKLGMLVGRLGKSARQRALINLSLCFPEYSDKEK
ENIVDAMFATASMAVVLMAELALSGPDKISHRIRWNGLEIVEKMAQNNEKVIFLVPHAWGVDIPAMLMAASGRKMAAMFH
NQRNPVVDYVWNSVRRRFGGKLHARNDGIASFVRSVRQGYWGYYLPDQDHGPEFSEFADFFATYKATLPVIGRLSRISGA
RIIPLFPVYDGKTHHLTIHVSPPLAIRQKSDAHIARQINEVVENFVRPHPEQYTWILKLLKTRKEGEEDPY
>SEQF1516_EDU85142.1 general secretion pathway protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVGETDPQLVGLLSRYPAWVLVPSGRIAFHQVTLPHRTWRQRLQVLPFLLEEQLATDIEQLHFAILHQSGDRCDVAVVE
KAVMHRWLAYCGQLGVREVRLLPDVLMLPLATEGWSAVKLAGQWLFRRDRYAGMTVELSWLTHFLSLTAPPVIESYSVPP
VPCPGPKTTEWRNQPGRDLLQLVAEGDGYDGADLRQGEFARQGTWYARFRPWRYVAGALLACVFLAGSNAGLAHYRLWQQ
AQFWRYESVRVYQQLFPSEKAVKDPRRQMLRHLQQSTGNNIPELGSVMRQLQQLLSETSTIRLQALAWDSSSQTLKIDLQ
AASFQALEHFQQIAGEKYLIQPGEIRQQPQGVESRLILRVNNERA
>SEQF1516_EDU85143.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLALLAPFTIGMLTSDKCNLRYLTENVPFAGTGGQSCMQDLYHSSG
>SEQF1516_EDU85144.1 leukotoxin secretion protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFYMKGLWDLVCRYKTVFSDVWKIRHTLDAPVREKDEYAFLPAHLELIETPVSRRSHFVVWSILLFVIISLLLSVLGKV
EVVSVANGKFTHSGRSKEIKPIENAIVEKIMVKDGSFVKKNDPLVELTVPGVESDILKSEASLLYEKTEQYRYAILSESI
QRNELPEIRITDFPGGEDNAGGEHFQRVSSLIKEQFMTWQNRKNQKQLTLNKKIVERDAALARVSLYEHQVSQEGRKLND
FKYLLNKKAVSQHSVMEQENSYIQAKNEHAVWLAQVSQLEKEIELVREELALETNIFRSEIIEKHRKSTDNIVLLEHELE
KNRQRKASSFIKAPVSGTVQELNIHTEGGVVTTAETLMIIVPDNDILEVTASVLNKDIGFIQPGQEVVIKVDAYPYTRHG
YLTGKVKNITADSVSVPDTGLVFNVIISVDRNDIQGERKKIPVTAGMTVMAEIKTGVRSVISYLLSPLKETINESLRER
>SEQF1516_EDU85145.1 w0003 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLIIFILIVLIIAALLIRIILRSVNQHSPLLMQLHAAGIRTGDAERILSGGEYDASHLRPERRRRDILLEEVLRQAGIP
LLRSHDARKLLQMTGEWLNTTGAAQQSPEHRS
>SEQF1516_EDU85146.1 catalase/peroxidase HPI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKKTLPVLILLALSGSFSTAVAADKKETQNFYYPETLDLTPLRLHSPESNPWGADFDYATRFQQLDMEALKKDIKDLLT
TSQDWWPADYGHYGPFFIRMAWHGAGTYRTYDGRGGASGGQQRFEPLNSWPDNVNLDKARRLLWPVKKKYGSSISWGDLM
VLTGNVALESMGFKTLGFAGGREDDWESDLVYWGPDNKPLADNRDKNGKLQKPLAATQMGLIYVNPEGPGGKPDPLASAK
DIREAFSRMAMDDEETVALIAGGHTFGKAHGAASPEKCIGAGPDGAPVEEQGLGWKNKCGTGNGKYTITSGLEGAWSTSP
TQFTMQYLKNLYKYEWELHKSPAGAYQWKPKKAANIVQDAHDPSVLHPLMMFTTDIALKVDPEYKKITTRFLNDPKAFEQ
AFARAWFKLTHRDMGPAARYLGNEVPAESFIWQDPLPAADYTMIDGKDIKSLKEQVMDLGIPASELIKTAWASASTFRVT
DYRGGNNGARIRLQPEINWEVNEPEKLKKVLASLTSLQREFNKKQSDGKKVSLADLIVLSGNAAIEDAARKAGVELEIPF
TPGRTDASQEQTDVASFSVLEPTADGFRNYYSKSRSHISPVESLIDKASQLDLTVPEMTALLGGLRVMDINTNNSSLGVF
TDTPGVLDNKFFVNLLDMSTRWSKADKEDTYNGFDRKTGALKWKASSVDLIFSSNPELRAVAEVYASDDARNKFIHDFVK
SWNKVMNSDRFDLNNK
>SEQF1516_EDU85147.1 w0046 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAPSYARYEKYTIHTIQFIHTVQNLHTLFLFSWSDPVSGGYGSSSPSAQRYIPSAQHAVPHSVAHGTICCVVSLDCDAPR
RGGKQRYDDFLRWYTSGKSFIQIKSDPYETGMR
>SEQF1516_EDU85148.1 bacterial Peptidase A24 N- domain family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSLPEFAVDYPLLWLICTGGLGGVTGSFLNVVIHRLPIMLERRWRREALTLLAHSVPESGPAFNLMIPQSHCPCCFHPL
GIRDNIPLLSYLFLKGKSRCCGERIPVYYPLVEITNSVLFILAASRFPPGLTLAAAWLFISMLLVLAVIDCHTALLPDVL
TLPLLWLGLLFSLQRGVVTLEEAVVGAVSGYLCLWGLYWLFRFATGREGLGYGDFKLAAALGAWMGWQALPSILLFASVS
GLIVTVLLRIVTATDFTRPLPFGPWLALSGVCHFLLM
>SEQF1516_EDU85149.1 general secretory pathway protein E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRVVQNVSESRPLLPFSFSRTQRILLLREQEGNRVFCMEDTPASALLEVRRVAEGPLNVTTVSAEAFEKQLVSSYQRDS
DEARQMMAEIGNEMDFYTVAGELPDREDLLDANDDAPIIRLINAMLTEAIKEKASDIHIETYERHLQVRFRIDGVLREIL
RLHRNLASLLISRIKVMARLDIAEKRVPQDGRMVLRIGGRAVDVRVSTLPSNHGERIVLRLLDKNSVSLDLAALGMSQQN
QRHIDALIRRPHGIILVTGPTGSGKSTTLYAALSLLNPRDRNIMTVEDPVEYELDGISQTQVNPKVDMTFARSLRAILRQ
DPDVVLVGEIRDGETAQIAVQASLTGHLVLSTLHTNSAAGALSRLQDMGIPPFLLSTSLLAVLAQRLVRTLCPRCRQPCQ
VSTELAMDMDIPPETTIWQPAGCQHCSFTGYHGRTGIHELLLIDDRIRTAIYQGEGELGITRLAGSRYLTLRGDGRQKVL
AGETSWEEVVRVTESRLQEEE
>SEQF1516_EDU85150.1 metalloprotease stce [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLKYLSCTILAPLAIGVFSATAADNNSAIYFNTSQPINDLQGSLAAEVKFAQSQILPAHPKEGDSQPHLTSLRKSLLLV
RPVKADDKTPVQVEARDDNNKILGTLTLYPPSSLPDTIYHLDGVPEGGIDFTPHNGTKKIINTVAEVNKLSDASGSSIHS
HLTNNALVEIHTANGRWVRDIYLPQGPDLEGKMVRFVSSAGYSSTVFYGDRKVTLSVGNTLLFKYVNGQWFRSGELENNR
ITYAQHIWSAELPAHWIVPGLNLVIKQGNLSGRLNDIKIGAPGELLLHTIDIGMLTTPRDRFDFAKDKEAHREYFQTIPV
SRMIVNNYAPLHLKEVMLPTGELLTDMDPGNGGWHSGTMRQRIGKELVSHGIDNANYGLNSTAGLGENSHPYVVAQLAAH
NSRGNYANGIQVHGGSGGGGIVTLDSTLGNEFSHEVGHNYGLGHYVDGFKGSVHRSAENNNSTWGWDGDKKRFIPNFYPS
QTNEKSCLNNQCQEPFDGHKFGFDAMAGGSPFSAANRFTMYTPNSSAIIQRFFENKAVFDSRSSTGFSKWNADTQEMEPY
EHTIDRAEQITASVNELSESKMAELMAEYAVVKVHMWNGNWTRNIYIPTASADNRGSILTINHEAGYNSYLFINGDEKVV
SQGYKKSFVSDGQFWKERDVVDTREARKPEQFGVPVTTLVGYYDPEGTLSSYIYPAMYGAYGFTYSDDSQNLSDNDCQLQ
VDTKEGQLRFRLANHRANNTVMNKFHINVPTESQPTQATLVCNNKILDTKSLTPAPEGLTYTVNGQALPAKENEGCIVSV
NSGKRYCLPVGQRSGYSLPDWIVGQEVYVDSGAKAKVLLSDWDNLSYNRIGEFVGNVNPADMKKVKAWNGQYLDFSKPRS
MRVVYK
>SEQF1516_EDU85151.1 membrane protein YijP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHLNTGQNRPTFSWSALGWAIFYFGFFSTLLQVIIFSSGYSGTNGIRDSLLFSCLWLIPVFLYPDRIKIIAAVVGFILWG
TSLAALCYYFLYGHEFSQSVLFVMFETNAREAGEYFSQYFSLKLLLISLVYTAVSVFLWTRLRPVYIPLPWRRIVSFLLL
YALLLHPVVLKSLIRQEPLNDTLGKLASRMEPAAPWQFVSSYYQYHQQLNALTTFLNENSALPPLGNLRDESGERPRTLV
LVIGESTQRERMSLYGYLRETTPELDALRKTDPGLTVFNNVVASRPYTIEALQQALTFANEKNPDLYLTQPSLMNMMKQA
GYKTFWITNQQTITARNTMLTVFSRQTDRQYYMNQQRTQSAREYDTNVLKPFREVLNDPAPKKLIIVHLLGTHIKYKYRY
PEGQGRFDGITGHIPTGLNAKELEVYNDYDNANLFNDHVVASLIKDFRATAPDGFLLYFSDHGEEVYDTPPYKTQGRNED
NPTRPMYTVPFLLWTSEKWHAAHPRDFSQYVDRKYSLAELIHTWSDLAGLTYDGYDPTRSLVNPQFRETTRWIGNPYKKN
GLTDFDTLPYGEP
>SEQF1516_EDU85152.1 type II secretion protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNELKKRLQYVSPRERRLLIGCVALLVVVFVYYVLWQPWLIREDKWRTVVTREKNTVEWMKQQVPNIKRREASMPEQGEP
LGLSAAVTRTSAAYGVSVTRLQPQGERLAVTLAPVEFNALMQWLTQLERRHRIRTMVFDVAAQGNPPGQVTVNRLVLSQD
DVNKDASLSR
>SEQF1516_EDU85153.1 plasmid maintenance protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSLSPDTVRRIEDAAAALIAAGTPNPTNEQVRQHLGGGSLSHISPVMRAFRARQREQATPLPPELAQLLTGQLGLLWQA
AVKQAEAGALAAREQADDDIARADKERDEALANVAALESELAVLREVVAERDRLLQEVRELRAEALPLREQVARLTATGE
HLAAQLQDTKAELKEAREDGRQLQTELLALARQDGKVKK
>SEQF1516_EDU85154.1 serine proteAse eata [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKIYSLKYSHITGGLIAVSELSGRVSSRATGKKKHKRILALCFLGLLQSSYSFASQMDISNFYIRDYMDFAQNKGIFQA
GATNIEIVKKDGSTLKLPEVPFPDFSPVANKGSTTSIGGAYSITATHNTKNHHSVATQNWGNSTYKQTDWNTSHPDFAVS
RLDKFVVETRGATEGADISLSKQQALERYGVNYKGEKKLIAFRAGSGVVSVKKNGRITPFNEVSYKPEMLNGSFVHIDDW
SGWLILTNNQFDEFNNIASQGDSGSALFVYDNQKKKWVVAGTVWGIYNYANGKNHAAYSKWNQTTIDNLKNKYSYNVDMS
GAQVATIENGKLTGTGSDTTDIKNKDLIFTGGGDILLKSSFDNGAGGLVFNDKKTYRVNGDDFTFKGAGVDTRNGSTVEW
NIRYDNKDNLHKIGDGTLDVRKTQNTNLKTGEGLVILGAEKTFNNIYITSGDGTVRLNAENALSGGEYNGIFFAKNGGTL
DLNGYNQSFNKIAATDSGAVITNTSTKKSILSLNNTADYIYHGNINGNLDVLQHHETKKENRRLILDGGVDTTNDISLRN
TQLSMQGHATEHAIYRDGAFSCSLPAPMRFLCGSDYVAGMQNTEADAVKQNGNAYKTNNAVSDLSQPDWETGTFRFGTLH
LENSDFSVGRNANVIGDIQASKSNITIGDTTAYIDLHAGKNITGDGFGFRQNIVRGNSQGETLFTGGITAEDSTIVIKDK
AKALFSNYVYLLNTKATIENGADVTTQSGMFSTSDISISGNLSMTGNPDKDNKFEPSIYLNDASYLLTDDSARLVAKNKA
SVVGDIHSTKSASIMFGHDESDLSQLSDRTSKGLALGLLGGFDVSYRGSVNAPSASATMNNTWWQLTGDSALKTLKSTNS
MVYFTDSANNKKFHTLTVDELATSNSAYAMRTNLSESDKLEVKKHLSGENNILLVDFLQKPTPEKQLNIELVSAPKDTNE
NVFKASKQTIGFSDVTPVITTRETDDKITWSLTGYNTVANKEATRNAAALFSVDYKAFLNEVNNLNKRMGDLRDINGEAG
AWARIMSGTGSASGGFSDNYTHVQVGVDKKHELDGLDLFTGFTVTHTDSSASADVFSGKTKSVGAGLYASAMFDSGAYID
LIGKYVHHDNEYTATFAGLGTRDYSTHSWYAGAEAGYRYHVTEDAWIEPQAELVYGSVSGKQFAWKDQGMHLSMKDKDYN
PLIGRTGVDVGKSFSGKDWKVTARAGLGYQFDLLANGETVLRDASGEKRIKGEKDSRMLMSVGLNAEIRDNVRFGLEFEK
SAFGKYNVDNAVNANFRYSF
>SEQF1516_EDU85155.1 relaxase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIAGLREEPAQDWLSLHKRLASDGLYITMQEGELVVKDGWDRAREGVALSSFGPLWTAEKLGRKLGEYQPVPTDIFSQV
GTPGRYDPEAINVDIRPEKVAETESLKQYACRHFAERLPEMARNGELESCLDVHRTLATAGLWMGIQHGHLVLHDGFDKQ
QTPVRADSVWPLMTLDYMQDLDGGWQPVPKDIFTQVIPGERFRGRNLGTQAVSDYEWYRMRMGTGPQGAIKRELFSDKES
LWGYTTVQCESLIEDMIAGGNFSWQACHEMFARKGLMLQKQHHGLVIVDAFNHELTPVKASSIHPDLTLSRAEPQAGPFE
IAGADIFERVKPECRYNPELAASDEVEPGFRRDPVLRRERREARAAAREDLRARYLAWKEHWRKPDLRYGERLREIHAAC
RRRKAYIRVQFRDPQLRKLHYHIAEVQRMQALIRLKESVKEERLSLIEEGKWYPLSYRQWVEQQAVQGDRAALSQLRGWD
YRDRRKDKRRTTNADRCVILCEPGGTPLYEDTGVLEARLQKDGSVRFRDRRNGELVCVDYGDRVVFYHHQDRNELVDKLN
LIAPVLFDREPGMGFEPEGSYQQFNDVFAEMVAWHNAAGITGNGHFVISRPDVDLHRQRSEQYYHEYIRQQKSISGGHGA
SYAPVQDNEWTPPSPGM
>SEQF1516_EDU85156.1 general secretion pathway protein F [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALFHYQASDIHGRKRSGILEADSARHARQLLREQALIPVRLDEKQVHHKHSLRSILRFRPRGGSSAELALLTRQLATLV
AASLPLEEALDALLRQSEKPRQRNLIAAVRTKVLEGHSLAAAMGMFPGTFERLYCAMVAAGETSGRLDVVLSRLADYTEQ
RQIMRNRLLQALLYPCVLTLVAVGVIAILLTAVVPKVVEQFIHMKQTLPLSTRVLMGAAEVSQTWGPWLLLAAALGGIAG
RMILHQPSQRLAFHHLLLRLPVVGRISRGLNTARYARTLSILNASAVPLLQAMHISGDVLSNDWARHQLATAAELVREGV
SLHQALEQTSLFPPMMRHMIASGENSGELDSMLERAADNQDREFSTQMQLALGLFEPLLVVGMAGVVLFIVLAILQPLLQ
LNNMMNM
>SEQF1516_EDU85157.1 hemolysin-activating lysine-acyltransferase HlyC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSNAFDVMGKVAWLWACSPLHKKWPLSVFAINVIPAIQTNQFALLIKDELPVAFCSWASLDLECEVKYINDVTSLYAKD
WMSGERKWFIDWIAPFGHNMELYKYMRKKYPYELFRAIRLDESSKTGKIAEFHGGGIDKKLASKIFRQYHHELMSEVKNR
QDFNFNIEKEN
>SEQF1516_EDU85158.1 general secretion pathway protein C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTPNRLLCVILLIAGYQLVSVIHHFWLTQAASVPGLSRVSAPETAVTGDQTEERFVFTLFGRASPLSSEGRAQETMPSL
SDDLLSGEDLDVRGILYSSVAEHSVAIFAHNNRQFSLSVGEKVPSYDATISAIFSDHIVINYQGKTVSLPLRYDNTEKKN
AYDNNNLTVGDVITQDNFRVESVFDIMSFSAVTVNNTLSGYRLIPGKHSSLFYNAGLHDNDLAVSVNGSELRDTRQAQQI
MKQLPELKEIKITVERDGQLYDAFIAVGEN
>SEQF1516_EDU85159.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKTKQEWLYQLRRCSSVNTLEKIIHKNRDSLSTSERESFNSAADHRLAELITGKLYDRIPKEIWKYVR
>SEQF1516_EDU85160.1 cytochrome b562 superfamily [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKSNKVIISCGMALYFLCGGITVAEELDESMQVLARNMSVLQSSMDKKELLEALDRMDDAVDESMKRLPESISPADEEG
KNDYIKELQKLEKEIMLAKQKVLSGQLSDIPDSVNKMNKIRVEGHDKFR
>SEQF1516_EDU85161.1 type II secretion protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLILLLMGITAGLVLMSFPDSAQNHLQQQRERLQAQLDYALDRSQQDGLLMGIQVRFDGWKFKVLQRGTAESPPTLAEGG
DIWQGYVWQTWQPRRAAMGGKLPDDVRLELQYLRGLQWMSEHDDGAEPDILLLPGGEVTPFRLLFRQVGEEAVVGLQVDE
NGLMTLFEGEVSL
>SEQF1516_EDU85162.1 12.7 kDa protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDSCGTNTYVRNITLWLERENRELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU85163.1 plasmid SOS inhibition protein PsiA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSARSQALVPLSTEQQAAWRAVAETEKRRNQGNTLAEYPYAGAFFRCLNGSRRISLSDLRFFMPSLTAEELHGNRLQWLY
AIDVLIETQGEVCLLPLPGDAAERLFPSVRFCVRERSRHKSALVMQKYSRQQAREAEQKARAYQALVAQAEIELAFHSPE
TVGSWYARWSDRVAEHDLETLFWQWGERFPSLAGMERWQWQDMPFWQVIAEASLAAKEAGHAVREMERWMVPNKLREVRD
AATITRIARKQPE
>SEQF1516_EDU85164.1 leukotoxin translocation ATP-binding protein LktB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMSKCSSHNSLYALILLAQYHNITVNAETIRHQYNTHTQDFGVTEWLLAAKSIGLKAKYVEKHFSRLSIISLPALIWRDD
GKHYILSRITKDSSRYLVYDPEQHQSLTFSRDEFEKLYQGKVILVTSRATVVGELAKFDFSWFIPSVVKYRRILLEVLTV
SAFIQFLALITPLFFQVVMDKVLVHRGFSTLNIITIAFIIVILFEVILTGARTYIFSHTTSRIDVELGAKLFRHLLALPV
SYFENRRVGETVARVRELEQIRNFLTGQALTSVLDLFFSVIFFCVMWYYSPQLTLVILLSLPCYVIWSLFISPLLRRRLD
DKFLRNAENQAFLVETVTAINTIKSMAVSPQMIATWDKQLAGYVASSFRVNLVAMTGQQGIQLIQKSVMVISLWMGAHLV
ISGEISIGQLIAFNMLAGQVIAPVIRLAHLWQDFQQVGISVERLGDVLNTPVEKKSGRNILPEIQGDIEFKNVRFRYSSD
GNVILNNINLYISKGDVIGIVGRSGSGKSTLTKLLQRFYIPETGQILIDGHDLSLADPEWLRRQIGVVLQENILLNRSII
DNITLASPAVSMEQAIEAARLAGAHDFIRELKEGYNTIVGEQGVGLSGGQRQRIAIARALVTNPRILIFDEATSALDYES
ENIIMKNMSRICKNRTVIIIAHRLSTVKNANRIIVMDNGFISEDGTHKELISKKDSLYAYLYQLQA
>SEQF1516_EDU85165.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPDALAAEGSSKRDRNRFLDSHYRRGWNVNVSRVMDNATHVAVYFGSYLKKPPVPMSRLEHYAGQDEIDPFN
>SEQF1516_EDU85166.1 w0044 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIYHYTDLNGLKGIIESGSLWATHFSFLNDSNELTHGMNCLENALQYLRDDFNPKTLKFIEQAPL
>SEQF1516_EDU85167.1 hypothetical protein ECH7EC4501_5182 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFFSDVIFLWLPCLLLFFFFFLFLFLLFFPFLSCLWLFRASPWRGGLS
>SEQF1516_EDU85168.1 IS911, transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKRNFSAEFKRESAQLVVDQNYTVADAAKAMDIGLSTMTRWVKQLRDERQGKTPKASPITPEQIEIRELRKKLQRIEME
NEILKKATTALLMSDSLNSSR
>SEQF1516_EDU85169.1 type IV secretion-like conjugative transfer system pilin acetylase TraX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTDNTNTTRNDSLAARTDTWLQSLLVWSPGQRDIIKTVALVLMVLDHANRILHLDQTWMFLAGRGAFPLFALVWGLNLS
RHAHIRQSAINRLWGWGIIAQFAYYLAGFPWYEGNILFAFAVAAQVLTWCETRSGWRTAAAILLMALWGPLSGTSYGIAG
LLMLAVSHRLYRAEDRTERLVLVACLLAVIPALNLASSDAAAVAGLVMTVLTVGLVSCAGKSLPRFWPGDFFPTFYGCHL
AVLGILAL
>SEQF1516_EDU85170.1 hemolysin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVNKIKNIFNNATLTTKSAFNTASSSVRSAGKKLILLIPDNYEAQGVGINELVKAADELGIEIHRTERDDTAIANQFFG
AAEKVVGLTERGVAIFAPQLDKLLQKYQKVGSKIGGTAENVGNNLGKAGTVLSALQNFTGIALSGMALDELLRKQREGED
ISQNDIAKSSIELINQLVDTVSSINSTVDSFSEQLNQLGSFLSSKPRLSSVGGKLQNLPDLGPLGDGLDVVSGILSAVSA
SFILGNSDAHTGTKAAAGIELTTQVLGNVGKAVSQYILAQRMAQGLSTTAASAGLITSAVMLAISPLSFLAAADKFERAK
QLESYSERFKKLNYEGDALLAAFHKETGAIDAALTTINTVLSSVSAGVSAASSASLIGAPISMLVSALTGTISGILEASK
QAMFEHVAEKFAARINEWEKEHGKNYFENGYDARHAAFLEDSLSLLADFSRQHAVERAVAITQQHWDEKIGELAGITRNA
DRSQSGKAYINYLENGGLLEAQPKEFTQQVFDPQKGTIDLSTGNVSSVLTFITPTFTPGEEVRERKQSGKYEYMTSLIVN
GKDTWSVKGIKNHKGVYDYSKLIQFVEKNNKHYQARIISELGDKDDVVYSGAGSSEVFAGEGYDTVSYNKTDVGKLTIDA
TGASKPGEYIVSKNMYGDVKVLQEVVKEQEVSVGKRTEKIQYRDFEFRTGGIPYDVIDNLHSVEELIGGKHDDEFKGGKF
NDIFHGADGNDYIEGNYGNDRLYGDDGDDYISGGQGDDQLFGGSGNDKLSGGDGNNYLTGGSGNDELQAHGAYNILSGGT
GDDKLYGGGGIDLLDGGEGNDYLNGGFGNDIYVYGQNYGHHTIADEGGKGDRLHLSDISFDDIAFKRVGNDLIMNKAING
VLSFNESNDVNGITFKNWFAKDASGADNHLVEVITDKDGREIKVDKIPHNNNERSGYIKASNIASEKNMVNITSVANDIN
KIISSVSGFDSGDERLASLYNLSLHQNNTHSTTLTTTV
>SEQF1516_EDU85171.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYCTVKEIIRDVLDTDVPDSECVFAVVLTRGDVRHIAQDWNLSDDELETVMQRLDDAFEYGADVSIVHDVVRELMEEKRA
SRQVTVPAVMLEKVMALAGSEMKRLYAVGSENGGDGDAFVREEREAMDVVLQALDGEHMS
>SEQF1516_EDU85172.1 general secretion pathway protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNGRLPVLVFTTVILGAIPGWGAEFSANFKDTDIQEFINTVSKNLHKTVIINPDVQGTITVRSYDMLNEEQYYQFFLSVL
DVYGFAVVDMHNGILKVVRSKDAKTSAVPVASDVSPGTGDEVVTRVVPVSNVAARDLAPLLRQLNDNAGAGSVVHYEPSN
VLLMTGRAAVMKRLMEIVERVDKVGNRSVATVPLTYASATDVARLVTELTKETDKTAIPAWMTAKLVADERTNSVLVSGE
PISQQRIISIIKQLDRQEDVQGNTKVIYLKYAKAKDLVEVLTGISSSIENDSKKSPSTEALRKGVTIKSHEQTNALILTG
APDVIRDLENVISQLDIRRPQVLVEAIIAEIQDADGLNLGIQWVNKHAGVAQFTSTGLPITTMVQTRQNEILDSDQSNAL
SMFNGIAAGFYQGNWAMLLTALSTSSKNDILATPSIVTLDNMEATFNVGQEVPVLSGSQTTSGDNIFNTVERKTVGIKLR
VKPQINEGDSVLLEIEQEVSGVADTAVATTTDLGATFNTRTVTNAMLVGNGETVVVGGLLDKSIRGSESKVPLLGDIPVL
GHLFRAKSEQTAKRNLMLFIRPTIIRERDGFRHASAEKYQSFNQEQVQSRGKETTALTLNEEQLRLSPDQDDTAFRKVKA
AIAAFYAQEM
>SEQF1516_EDU85173.1 IS629 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKREIQRVYDENHQVYGVRKVWRQLLREGIR
VARCTVARLMAVMGLAGVLRGKKIRTTVSRKAVSAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGCIV
GWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTERLKEAKLLASTGSTGDSYDNAMAESINGLYKAEV
IHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHIPPAEAEKAYYASIRNDDLAA
>SEQF1516_EDU85174.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSAAITMTAPEAASPVQMYRATYSPDDNKLRLYAVSRLDPETYKKVHDAGFRWAPKQALFVAPAWTPGREDVLLSLAGE
IEDEDSTLAERQEARAERFTGYSGKRASESAQALDEVERLAAMIPPGQPILVGHHSERRARRDAQRIENGMKRAVMLFER
AEYWEERGRSALLHAKYKERPDVRWRRIKKIEADLRKAEKTIAQSQKYLTMWRAESLDLNMAKLISSHDHISACFPLDTY
PRPAEKSQYEGSRSLWSALDDDIITTEQAREIAIRCHERQIQHQQRWVNHYQNRLNYERAMLDESGGVVTRTQDFEPGGQ
VFSRGEWLTIIRVNKSNGAVSSVTTPNYSFLGYSGTMKVTPDRITDYKAPSAEEAAVASQAAKRPPVVNYPGEGFREMTK
AQWAALPRDCKAVRSVAEAEDHGAYRYRRTMDNNFRLVNVYITDMKITEIPQK
>SEQF1516_EDU85175.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNISTETREILRNYKAVINARRREMGQKPLTTAQIVDEICDFVANQQAVFLGGHYILQGSRNR
>SEQF1516_EDU85176.1 IS911, transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTLCHVFGVHRSSYRYWKNRPEKPDGRRAVLRSQVLELHNISHGSAGARSIATMATLRGFRMGRWLAGRLMKELGLVSC
QQPAHRYKRGGREHVTIPNHLGRQFAVTEPNQVWCGDVTYIWTGKRWAYLAVVLDLFARKPVGWAMSFSPDSRLTIKALK
MAWEIRSKPAGVMFHSDQGSHYTSRQFRQLLWRYQIKQSLSRRGNCWDNSPMERFFRSLKNEWIPVTGYMNFSDAAHEIT
DYIVGYYNALRPHEYNGGLPPNESENRYWKNSKAVASFC
>SEQF1516_EDU85177.1 transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWHGSLAGRSSPALLMLPRFADIFQQGNRWLNWLEKQPEGSVRPVVIESVTKIMACGTTLMGYTQWCCSSPDCSHIKKVC
FRCKSRSCPHCGVKAGAQWIQYLLSLVPDCPWQHIVFTLPCQYWSLVFHNRWLLAEMSRIAADVIQEICRQADVRLRTRT
TICQLRQIC
>SEQF1516_EDU85178.1 hypothetical protein ECH7EC4501_5114 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFYEGSNASASGYGVTHVRDRQMTAQLQAALQETEYKLQ
>SEQF1516_EDU85179.1 transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSREDFYMIKQMRQQGAYIVDIATQIGCSERTVRRYLKYPEPPARKTRHKMAEMDYIDMRLAENVWNGEVILAEIKAMG
YTGGRSMLLRQFRKTPEQRFTQEHSLFFRLLNRRYEKASIVLTSNKGFADWGRDVR
>SEQF1516_EDU85180.1 resolvase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVPAVYSAGQPASLPVAIDYPAALALRQMSMVHDELPKYLLAPEVSALLHYVPNLHRKMLLATLWNTGARINEALALTRG
DFSLAPPYPFVQLATLKQRTEKAARTAGRMPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNRRTGRTEKARIWEV
TDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIPLKVLQSLMGHKSISSKEVYTKVFALDVAARHRVQ
FAMPESDAVAMLKQLS
>SEQF1516_EDU85181.1 plasmid stabilization system protein, RelE/ParE family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELKWSSKALSDLARLYDFLVLASKPAAARTVQSLTQAPVILLTHPRMGEQLFQFEPREVRRIFAGEYEIRYELNGQTIY
VLRLWHTRENR
>SEQF1516_EDU85182.1 general secretion pathway protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKGQEGMTLLEVIVALVVFALAGMALMQASTQQAAGIGRMEEKVLAGWLADNQMVQLQLEKTWPENGWGEKTISFAGTEW
YLRWGGPDSDVPQPRSLEVEVRRTKEETSALVSLRSSVVRE
>SEQF1516_EDU85183.1 general secretion pathway protein J [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQQRVKGFTLLEMLLALAVFAALSISAFQVLQGGIRAHELSRDKVQRLAELQRGISQMERDLTQMLPRHSRGNEGLLLA
APHLLKSDDWGISFTRNSWLNPAGMLPRPELQWVGYRLRQQKLERLSYFHVDHPSGVSPDVRVMLDGVHAFRLRFFVNGD
WQARWDSTGILPQAVEVTLVMDDFAELPRLFLVSKETAE
>SEQF1516_EDU85184.1 repFIB replication protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNTLSRTDATEELTRLSLARAEGFDKVEITGPRLDMDND
FKTWVGIIHSFARHNVIGDKVELPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSA
YYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPAPVSLARLRARLNLKSPVFSQNQ
TVRRAMEQLREIGYLDYTEIQRGRTKLFCIHYRRPRLKAPNDESKENPLPPSPAEKVSPEMAEKLALLEKLGITLDDLEK
LFKSR
>SEQF1516_EDU85185.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVLESQGEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGSGDGGLTTAERQRLKELERENRELRVQFFRLLNRRYEK
ASIILTSNKGFADWGEMFGEHVLATAILDRLLHHSTTLNIKGESYRFNIPDRLVVHLSLHARPELRAHNT
>SEQF1516_EDU85186.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNYDEITKITAERISDYMTEAVNTDSIAVAEMFHNAAWGVRTLWFELVTKIDIDIHKKNRYASYDLDR
>SEQF1516_EDU85187.1 post-segregation antitoxin CcdA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQRITVTVDSDSYQLLKAYDVNISGLVSTTMQNEARRLRAERWKAENQEGMAEVARFIEMNGSFADENRDW
>SEQF1516_EDU85188.1 hypothetical protein ECH7EC4501_5105 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPASGNENDLNMPSGTIEIFVRCYVEVERIMSAMDRTT
>SEQF1516_EDU85189.1 UDP-sugar hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKILFTESSSDIGGQELQALAQMTALQKQGHSVLLACREKSKIAPEARKRGHDVTFIPFRNSLHLPSILRLRRIIGEFK
PDLVICHSGHDSNIAGLSRLICCHRFSIVRQKTYITRKTRTFSLNYLCDFIVVPSSAMMAHLMAEGVRTPVTVIPPGFDW
PALHNEAMRPLPLHIHAWAASADNVPLIVQVGMLRPEKGHEFMLRVLYQLKMEGKSFRWLVVGAGREEYEARLRQQTEHL
GMSGDVLMAGALFPALPVYRIASVVVMPSENEAFGMVLAEASVSGVPVIASETGGIPDVIQKNVTGTLLPVGDVSAWTGA
LRDFLSRPERFRMMAASAREDIEYRFDINRTAQIIVSLASQAKGKCNR
>SEQF1516_EDU85190.1 hypothetical protein ECH7EC4501_5178 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGFCLFRPVICLLLMMLLFMLLLLLLLLLLLLLLLLFFFFLLL
>SEQF1516_EDU85191.1 cytotoxic protein CcdB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSDKVSRELYPVVHIGDESWRMMTTDMASVPVSVIGEEV
ADLSHRENDIKNAINLMFWGI
>SEQF1516_EDU85192.1 general secretion pathway protein G [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKQHQRGFTLLEIMVVIVILGVLASLVVPNLMGNKDKADRQKVMSDLVALESTLDMYRLDNNRYPTTEQGLRALVSKPT
VQPEPRNYRQDGYIRRLPQDPWGGDYQLLNPGQYSDIDIFSPGPDGVPNTEDDIGNWTLGNAQP
>SEQF1516_EDU85193.1 paraquat-inducible protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAWDAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTS
EITLLEIPGVLFSEDYASLGTFFLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIRQGLRSCSCCTAILPADEPVCPR
CGTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIMVTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKM
IAIAWLCWDAKGHGKRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIMTMFSAMTF
DPRLSWDRQPESEHEES
>SEQF1516_EDU85194.1 alkanesulfonate monooxygenase, FMNH(2)-dependent [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGYTGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRP
SVTSPTVAARQAATLDRLSNGRALFNLVTGSDPQELAGDGVFLDHSERYEASAEFTQVWRRLLLGETVDFNGKHIHVRGA
KLLFPPIQQPYPPLYFGGSSDVAQELAAEQVDLYLTWGEPPELVKEKIEQVRAKAAAHGRKIRFGIRLHVIVRETNDEAW
QAAERLISHLDDETIAKAQAAFARTDSVGQQRMAALHNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYA
ALGIDSFVLSGYPHLEEAYRVGELLFPHLDVAIPEIPQPQPLNPQGEAVENDFIPRRVAQS
>SEQF1516_EDU85195.1 hypothetical protein ECH7EC4501_3000 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTILLTICAIGSIDKQVKFSRHYHLCYLNFPLYKPIK
>SEQF1516_EDU85196.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQLRAELSHLLGEKLSRIECVNEKADTALWALYDSQGNPMPLMARSFSTPGKARQLAWKTTMLARSGTVRMPTIYGVMT
HEEHPGPDVLLLERMRGVSVEAPARTPERWEQLKDQIVEALLAWHRQDSRGCVGAVDNTQENFWPSWYRQHVEVLWTTLN
QFNNTGLTMQDKRILFRTRECLPALFEGFNDNCVLIHGNFCLRSMLKDSRSDQLLAMVGPGLMLWAPREYELFRLMDNSL
AEDLLWSYLQRAPVAESFIWRRWLYVLWDEVAQLVNTGRFSRRNFDLASKSLLPWLA
>SEQF1516_EDU85197.1 putative peptidoglycan binding domain [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLNMMCGRRLSAISLCLAVTFAPLFNAQADEPEVIPGDSPVAVSEQGEALPQAQATAIMAGILPLPEGAAEKARTQIES
QLPAGYKPVYLNQLQLLYAARDMQPMWENRDAVKAFQQQLAEVAIAGFQPQFNKWVELLTDPGVNGMARDVVLSDAMMGY
LHFIANIPVKGTRWLYSSKPYALATPPLSVINQWQQALDKGQLPTFVAGLAPQHPQYAVMHESLLALLSDTKPWPQLTGK
ATLRPGQWSNDVPALREILQRTGMLDGGPKITLPGDDTPTDAVVSPSAVTVETAETKPMDKQTTSRSKPAPAVRAAYDNE
LVEAVKRFQAWQGLGADGAIGPATRDWLNVTPAQRAGVLALNIQRLRLLPTELSTGIMVNIPAYSLVYYQNGNQVLDSRV
IVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVRNDPGYLESHGYTVMRGWNSREAIDPWQVDWSTITASNLP
FRFQQAPGPRNSLGRYKFNMPSSEAIYLHDTPNHNLFKRDTRALSSGCVRVNKASDLANMLLQDAGWNDKRISDALKQGD
TRYVNIRQSIPVNLYYLTAFVGADGRTQYRTDIYNYDLPARSSSQIVSKAEQLIR
>SEQF1516_EDU85198.1 asparagine tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDGSCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKV
VASPGQGQQFEIQTSKVEVAGWVEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWV
STPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGETYACALSKIYTFGPTFRAENSNT
SRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKAVLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTEAVTIL
ENCGRKFENPVYWGVDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIGGSQREERL
DVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQNVRDVIPFPRTPRNASF
>SEQF1516_EDU85199.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPVLLETEARVLTADESKS
>SEQF1516_EDU85200.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVWSVHIRDKECALCFTNGKGATKKAALASALGEYFERL
STNYFFADFWLGETIANGPFVHYPNEKWFPLTENDDVPEGLLDERLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTR
QSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPEIPADVLARYPAVVEAIETLEAE
GFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGAHPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLE
THFIDSSGLISWDLFKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSDIYPAEDLW
LANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLGLATGSDNGWYTLRIGELKAMLALAGGDLEQ
ALVWTEWTMEFNSSVFSPERANYYRCLQTLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDL
HAFAAHQSLLKAYEKLQRAKAAFWAK
>SEQF1516_EDU85201.1 Tat (twin-arginine translocation) pathway signal sequence domain/peptidase M15 family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNNLHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANK
IKSIDPGLFDQLYRLQGLLGTRKPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRA
GGVGYYPRSNFVHIDTGPARHW
>SEQF1516_EDU85202.1 aminopeptidase N [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVRHGASDAPLCLNGEDLKLVSVHINDEPWTAWKEEEGA
LVISNLPERFTLKIINEISPAANTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKTKYPFLLSNGN
RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRGNLDRAPWAMTSLKNSMKWDEER
FGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKE
GLTVFRDQEFSSDLGSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIHTLLGEENF
QKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPVVTVKDDYNPETEQYTLTISQRTPATPDQAEKQP
LHIPFAIELYDNEGKVIPLQKGGHPVNSVLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARN
DFSRWDAAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNEMAELFDIIDPIAIAEV
REALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRNACLRFLAFGETHLADVLVSKQYHEANNMTDALAALSAA
VAAQLPCRDALMQEYDDKWHQDGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFHAE
DGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLENLSGDLYEKITKALA
>SEQF1516_EDU85203.1 periplasmic pilus chaperone family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVSLTAILLSCSSTWAAGKGGVGLAATRLVYSEGEEQISLGVRNTSPDVPYLIQSWVMTPDNKKSADFIITPPLFVLNP
ANENLLRIMYIGAPLAKDRETLFFTSVRAVPSTTKREEGNTLKIATQSVIKLFWRPKGLAYPLGEAPAKLRCTSSADMVT
VSNPTPYFITLTDLKIGGKLVKNQMISPFDKYQFSLPKGAKNSSVTYRTINDYGAETPQLNCKS
>SEQF1516_EDU85204.1 metallo-beta-lactamase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDASGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPE
KEDEFWLQGLPAQSRMFGLEECQPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGR
SDFPRGDHNQLISSIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW
>SEQF1516_EDU85205.1 dimethylsulfoxide reductase, B subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTQYGFFIDSSRCTGCKTCELACKDYKDLMPEVSFRRIYEYAGGDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCP
SGAMHKREDGFVVVDEDVCIGCRYCHMACPYGAPQYNETKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
KHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV
>SEQF1516_EDU85206.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLFTLKKVIGNMLLPLPLMLLIIGAGLALLWFSRFQKTGKIFISIGWLALLLLSLQPVADRLLRPIESTYPTWNNSQKVD
YIVVLGGGYTWNPQWAPSSNLINNSLPRLNEGIRLWRENPGSKLIFTGGVAKTNTVSTAEVGARVAQSLGVPREQIITLD
LPKDTEEEAAAVKQAIGDAPFLLVTSASHLPRAMIFFQQEGLNPLPAPANQLAIDSPLNPWERAIPSPVWLMHSDRVGYE
TLGRIWQWLKGSSGEPRQE
>SEQF1516_EDU85207.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLPHLSLADARNLHLAAQGLLNKPRRRASLEDIPATISRMSLLQIDTINIVARSPYLVLFSRLGNYPAQWLDESLARGE
LMEYWAHEACFMPRSDFRLIRHRMLAPEKMGWKYKDAWMQEHEAEIAQLIQHIHDKGPVRSADFEYPRKGASGWWEWKPH
KRHLEGLFTAGKVMVIERRNFQRVYDLTHRVMPDWDDERDLVSQTEAEIIMLDNSARSQGIFREQWLADYYRLKRPALAA
WREARAEQRQIIAVHVEKLGNLWLHADLLPLLERALAGKLTATHSAVLSPFDPVVWDRKRAEQLFDFSYRLECYTPAPKR
QYGYFVLPLLHRGQLVGRMDAKMHRQTGILEVISLWLQEGIKPTTTLQKGLRQAITDFANWQQATRVTLGHCPQGLFTDC
RTGWEIDPVA
>SEQF1516_EDU85208.1 putative sulfonate ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATPVKKWLLRVAPWFLPVGIVTVWQLASSVGWLSTRILPSPEGVVMAFWTLSASGELWQHLAISSWRALIVFSIGGSLG
LILGLISGLSRWGERLLDTSIQMLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARS
YGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREFLQTDVVVVAIILYALLGKLADV
SAQLLERLWLRWNPAYHLKEATV
>SEQF1516_EDU85209.1 nicotinate phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGDDLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFF
KADYLNWLREFRFNPEQVTVSNDNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSAL
TAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQAHEWFQAHQQISPDLANSQRAA
LAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASRYQGLRHDSGDPVEWGEKAIAHYEKLEIDPQSKTLVFSDNLDLRK
AVELYRHFSSRVQLSFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFDLPHIKKAS
>SEQF1516_EDU85210.1 putative RNA methylase family UPF0020 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSLFASTARGLEELLKTELENLGAVECQVVQGGVHFKGDTRLVYQSLMWSRLASRIMLPLGECKVYSDLDLYLGVQAIN
WTEMFNPGATFAVHFSGLNDTIRNSQYGAMKVKDAIVDAFTRKNLPRPNVDRDAPDIRVNVWLHKETASIALDLSGDGLH
LRGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGLHRGRWGFSGWAQHDEAIWQEVK
AEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNARLAGIGELITFEVKDVAQLTNPLPKEPYGTVLSNPPYGERLDSEP
ALIALHSLLGRIMKNQFGGWNLSLFSASPDLLSCLQLRADKQYKAKNGPLDCVQKNYHVAESTPDSKPAMVAEDYANRLR
KNLKKFEKWARQEGIECYRLYDADLPEYNVAVDRYADWVVVQEYAPPKTIDAHKARQRLFDIIAATISVLGIAPNKLVLK
TRERQKGKNQYQKLGEKGEFLEVTEYNAHLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSATVHAGLGG
ARSTTTVDMSRTYLEWAERNLRLNGLTGRAHRLIQADCLAWLREANEQFDLIFIDPPTFSNSKRMEDAFDVQRDHLALMK
DLKRLLRAGGTIMFSNNKRGFRMDLDGLAKLGLKAQEITQKTLSQDFARNRQIHNCWLITAA
>SEQF1516_EDU85211.1 DNA internalization-related competence protein ComEC/Rec2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKITTVGVCIICGIFPLLILPQLPGTLTLAFLTLFACVLAFIPVKTVRYIALTLLFFVWGILSAKQILLAGETLTGATQD
AIVEITATDGMTTHYGQITYLQGQRIFPAPGLVLYGEYLPQAVCAGQLWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRDTGTAHLMAISGLHIAFAALLAA
GLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTGMQPPALRTVVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPV
VILSQSLWLSAAAVAALIFWYQWFPCPEWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANLLAIPLVTF
ITVPLILAAMVVHLSGPLILDQGLWFLADRSLALLFLGLKSLPEGWINIAERWQWLSFSPWFLLVVWRLNAWRTLPAMCV
AVGLLMCWPLWQKPRPDEWQVYMLDVGQGLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHL
DHRGGLDSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSAHWPLQGRNDKGNNHSCVVKVDDGTNSILLTGDIEA
PAEQKMLSRYWQQVQATLLQVPHHGSNTSSSLPLIQRVNGKVALASASRYNAWRLPSNKVKHRYQQQGYTWLDTPHQGQV
TVDFSAQGWRISSLREQILPRWYHQWFGVPVDNG
>SEQF1516_EDU85212.1 seryl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGE
ELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGS
RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEV
PLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLG
LPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLV
AVMENYQQADGRIEVPEVLRPYMNGLEYIG
>SEQF1516_EDU85213.1 outer membrane protein F [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHYFSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGY
GQWEYNFQGNNSEGADAQTGNKTRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVAT
YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADRTNLQEAQLLGNGKKAEQWATGL
KYDANNIYLAANYGETRNATPITNKFTNISGFANKTQDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVG
ATYYFNKNMSTYVDYIINQIDSDNKLGVGSDDTVAVGIVYQF
>SEQF1516_EDU85214.1 SmtA protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQKLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMID
RAKQAAEAKGVSDNMQFIHCAAQDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
VAGNFDYVQAGMPKKKKRTLSPDYPRDPTQVYLWLEEAGWQIMGKTGVRVFHDYLREKHQQRDCYEALLELETRYCRQEP
YITLGRYIHVTARKPQSKDKV
>SEQF1516_EDU85215.1 putative formate transporter FocA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVFISIAFVFYITATTGTGTMPFGMAKLVGGICFSLGLI
LCVVCGADLFTSTVLIVVAKASGRITWGQLAKNWLNVYFGNLVGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKVHHT
FIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIPMGIVIRDFASPEFWTAVGSAPE
NFSHLTVMNFITDNLIPVTIGNIIGGGLLVGLTYWVIYLRENDHH
>SEQF1516_EDU85216.1 major facilitator family transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTYTRPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVGVVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFI
FAAGCAGLGLMIGFWSWLAWRFVAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSV
LPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITSMLKLRQARLGVNGCIISGIVLGSLYGLMPLYLNHKGVSNASIGFW
MAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVILGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLV
AMNQALLLSYTVGSLLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV
>SEQF1516_EDU85217.1 fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHIYGNVVDQGCDVATKSALQNIHIGDFNISDFQAANTVSTAADLNIDITGCAAGITGADVLFSGEADTLAPTLLKLTDT
GGSGGMATGIAVQILDAQSQQEIPLNQVQPLTPLKAGDNTLKYQLRYKSTKAGATGGNATAVLYFDLVYQ
>SEQF1516_EDU85218.1 chromosome partition protein MukE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNHAFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRST
TLIPRSVLSELDMMVGKILCYLYLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDIDRQKLQEKVRSSLN
RLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQLNDETEENQPDSGEEE
>SEQF1516_EDU85219.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAFDLHRMAFDKVPFDFLGEVALRSLYTFVLVFLFLKMTGRRGVRQMSLFEVLIILTLGSAAGDVAFYDDVPMVPVLIV
FITLALLYRLVMWLMAHSEKLEDLLEGKPVVIIEDGELAWSKLNNSNMTEFEFFMELRLRGVEQLGQVRLAILETNGQIS
VYFFEDDKVKSGLLILPSDCTQRYKVVPESADYACIRCSEIIHMKAGEKQLCPRCANPEWTKASRAKRVT
>SEQF1516_EDU85220.1 amino acid permease family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLLFHTLLFCFFYLTCFFPNFIRLKIKCAAGYNFAFRYFRTSYLPRIIPRFTDAPLILAKDLSMAGNVQEKQLRWYNIA
LMSFITVWGFGNVVNNYANQGLVVVFSWVFIFALYFTPYALIVGQLGSTFKDGKGGVSTWIKHTMGPGLAYLAAWTYWVV
HIPYLAQKPQAILIALGWAMKGDGSLIKEYSVVALQGLTLVLFIFFMWVASRGMKSLKIVGSVAGIAMFVMSLLYVAMAV
TAPAITEVHIATTNITWETFIPHIDFTYITTISMLVFAVGGAEKISPYVNQTRNPGKEFPKGMLCLAVMVAVCAILGSLA
MGMMFDSRNIPDDLMTNGQYYAFQKLGEYYNMGNTLMVIYAIANTLGQVAALVFSIDAPLKVLLGDADSKYIPASLCRTN
ASGTPVNGYFLTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAFIAVVRLAQKYTPEYVFIRNKPLAM
TVGIWCFAFTAFACLTGIFPKMEAFTAEWTFQLALNVATPFVLVGLGLIFPLLARKANSK
>SEQF1516_EDU85221.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFARKMLTPDAFSPAGFCVDDAALYFSFEEKCRDFNLSKEQKAELVLN
ALVAIRYLKPQMPKSWHFVSHGEMWVPMPGDAACVWLSDTNEQVNLLVVESGENAALCLLAQPCVVIAGRAMQLGDAIKI
MNDRLKPQVNVDSFSLEQAV
>SEQF1516_EDU85222.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVGRSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQE
DTRMMFQDARLLPWKSVIDNVGLGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPL
GALDALTRLEMQDLIVSLWQEHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVDIPRPRRLGSVRLAELEAEVLQR
VMQRGESETRLRKQG
>SEQF1516_EDU85223.1 ribosomal protein S1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKSESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFG
ETLLSREKAKRHEAWITLEKAYEDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLD
QKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLLHITDMAWKRVKHPSEIVNVGDE
ITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPEGTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSK
VVNVGDVVEVMVLDIDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVHLSDISWNV
AGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKKGAIVTGKVTAVDAKGATVELADGVEGYLRA
SEASRDRVEDATLVLSVGDEVEAKFTGVDRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE
>SEQF1516_EDU85224.1 anaerobic dimethyl sulfoxide reductase, A subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSALTLPFSRIAHAVDSAIPTKSGEKVIWSACTVNCGSRCPLRMHVVDG
EIKYVETDNTGDDNYDGLHQVRACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGN
ESIYLNYGTGTLGGTMTRSWPPGNTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYGGWADGNSPSDIENSKLVVLFGN
NPGETRMSGGGVTYYLEQARQKSNARMIIIDPRYTDTGAGREDEWIPIRPGTDAALVNGLAYVMITENLVDQAFLDKYCV
GYDEKTLPASAPKNGHYKAYILGEGPDGVAKTPEWASQITGVPADKIIKLAREIGSTKPAFISQGWGPQRHANGEIATRA
ISMLAILTGNVGINGGNSGAREGSYSLPFVRMPTLENPIQTSISMFMWTDAIERGPEMTALRDGVRGKDKLDVPIKMIWN
YAGNCLINQHSEINRTHEILQDDKKCELIVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFNDQVIKPR
FECKTIYEMTSELAKRLGVEQQFTEGRTQEEWMRHLYAQSREAIPELPTFEEFRKQGIFKKRDPQGHHVAYKAFREDPQA
NPLTTPSGKIEIYSQALADIAATWELPEGDVIDPLPIYTPGFESYQDPLNKQYPLQLTGFHYKSRVHSTYGNVDVLKAAC
RQEMWINPLDAQKRGIHNGDKVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDAKRVDKGGCINVLTTQRPSPLAK
GNPSHTNLVQVEKV
>SEQF1516_EDU85225.1 phosphoserine aminotransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQIFNFSSGPAMLPVEVLKQAQQELRDWNGLGTSVMEVSHRGKEFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQF
AAVPLNILGDKTTADYVDAGYWAASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAID
ETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKANVACPSILDYSILNDNGSMFNT
PPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELLYGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAA
GLHALKGHRVVGGMRASIYNAMPLEGVKALTDFMVEFERRHG
>SEQF1516_EDU85226.1 NADPH-dependent FMN reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAAEDLLYARFDSPALHTFTEQLQQADGLIVATPVYKAA
YSGALKTLLDLLPERALQGKVVLPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHKPQFTPNLQTR
LDTALETFWQALHRRDVQVPDLHSLRGNAHA
>SEQF1516_EDU85227.1 leucine responsive regulatory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEI
TLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLV
IKTR
>SEQF1516_EDU85228.1 dihydroorotate oxidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPAKPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFG
SIEIGTVTPRPQPGNDKPRLFRLVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICME
KIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQAMHHKYVPIAVKIAPDLSEEELIQVADSLVRHNID
GVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKSTEIIRRLSLELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSG
FIFKGPPLIKEIVTHI
>SEQF1516_EDU85229.1 chromosome partition protein MukF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLDGEMSEGELVDAFRHVSDAFEQTSETIGVRANNAIND
MVRQRLLNRFTSEQAEGNAIYRLTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPL
KYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDAT
MTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIGYDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALSYANA
DRLLDMRDEEMALRDEEVTGELPPDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRARHFDVARI
VIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY
>SEQF1516_EDU85230.1 peptidase, M48B family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNTKLLLAIVTSAALLTGCQNTHGIDTNMAISSGLNAYKAATLSDADAKAIANQGCAEMDSGNQVASKSSKYGKRLAKI
AKALGNNINGTPVNYKVYMTSDVNAWAMANGCVRVYSGLMDMMNDNEIEGVLGHELGHVALGHSLAEMKASYAIVAARDA
ISATSGVASQLSRSQLGDIAEGAINAKYSRDKESEADDFSFDLLKKRGISTQGLVGSFEKLASLDGGRTQSMFDSHPPST
ERAQHIRDRIASGK
>SEQF1516_EDU85231.1 ABC transporter, periplasmic substrate-binding protein, aliphatic sulfonates family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNIIKLALVGLLSVSTIVVAAESSPEALRIGYQKGSIGMVLAKSHQLLEKRYPQSKISWVEFPAGPQMLEALNVGSIDL
GSTGDIPPIFAQAAGADLLYVGVEPPKPKAEVILVAENSPIKTAADLKGHKVAFQKGSSSHNLLLRALRQAGLKFTDIQP
TYLTPADARAAFQQGNVDAWAIWDPYYSAALLQGGVRVLKDGTDLNQTGSFYLAARPYAEKNGAFIQGVLATFSEADALT
RSQREQSIALLAKTMGLPAPVIASYLDHRPPTTIKPVNAEVAALQQQTADLFYENRLVPKKVDIRQRIWQPTQLEGKQL
>SEQF1516_EDU85232.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKSTLMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNVE
GSVYDFVAEGIEEQAEYLKRYHDISRLVMNDPSEKNLNELAKVQEQLDHHNLWQLENRINEVLAQLGLDPNVALSSLSGG
WLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRNMATRIVDLDRGKLVTYPGNYDQ
YLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKARRTRNEGRVRALKAMRRERGERREVMGTAKMQVEEASRSGKIVF
EMEDVCYQVDGKQLVKDFSAQVLRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRAELDPDKTV
MDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLLLARLFLKPSNLLILDEPTNDLDVETLELLE
ELIDSYQGTVLLVSHDRQFVDNTVTECWIFEGGGKIGRYVGGYHDARGQQEQYVALKQPAVKKNEEPAAPKAETVKRSSS
KLSYKLQRELEQLPQLLEDLEAKLEALQTQVADASFFSQPHEQTQKVLADMAAAEQELEQAFERWEYLEALKNGG
>SEQF1516_EDU85233.1 chromosome partition protein MukB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTMAAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGK
LKAGVCYSMLDTINSRHQRVVVGVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAM
EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLRDYLLPENSGVRKAFQDMEAALR
ENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMRHANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHN
GAEGDLEADYQAASDHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEVDELKSQLA
DYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADSAAEWLETFQAKELEATEKMLSLEQKMSMAQTAHSQFEQAYQ
LVVAINGPLARNEAWDVARELLREGVDQRHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQ
ELEARIASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTSSQDVTEYLQQLLERER
EAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFGGVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQV
TEHLEGLTDCPEDLYLIEGDPQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLSER
FATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHENDNQQQRIQFEQAKEGVTALNRIL
PRLNLLADDSLADRVDEIRERLDEAQEAARFVQQFGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFAL
TEVVQRRAHFSYSDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDTKKELLNDLQR
ELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAEMDNLTRKLRKLERDYFEMREQVVTAKAGWCAV
MRMVKDNGVERRLHRRELAYLSADDLRSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQ
DIIRTDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGLQNVSFGQVNSVRLNVNVR
ETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLNPQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRA
ESGALSTGEAIGTGMSILVMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPENISP
EKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQAS
>SEQF1516_EDU85234.1 isochorismatase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKPYVRLDKNDAAVLLVDHQAGLLSLVRDIEPDKFKNNVLALGDLAKYFNLPTILTTSFETGPNGPLVPELKAQFPDAP
YIARPGNINAWDNEDFVKAVKATGKKQLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNEITRHSAWDRMSQAGA
QLMTWFGVACELHRDWRNDIEGLATLFSNHIPDYRNLMTSYDTLTKQK
>SEQF1516_EDU85235.1 outer membrane lipoprotein carrier protein LolA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESIL
VSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQ
FSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>SEQF1516_EDU85236.1 MOSC domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLTRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGTFITARQFPQMVRFTPSPVHDGLHLTAPDSSSAYVRF
ADFATQDAPTEVWGTHFTARIAPEAINKWLSGFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQ
RCPASVKMEQFRPNLVVSGASAWEEDSWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQKHPAGEPLKTLQSFRTAQDNGD
VDFGQNLIARNSGVIRVGDEVEILTTAPAKIYGAAAADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIP
YSCRAGICGSCRVQLLEGEVTPLKKSAMGDDGTILCCSCVPKTALKLAR
>SEQF1516_EDU85237.1 anaerobic dimethyl sulfoxide reductase, C subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRVIACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVG
ASALSNEIASGSIFFAVGGIGWLLAMLKKLSPALRTLWLVVTMVLGVVFVWMMVRVYNSIDTVPTWYSIWTPMGFFLTMF
MGGPLLGYLLLSLAGVDGWAMRLLPAISVLALVVSGVMSVMQGTELATIHSSVQQAAALVPDYGALMSWRIVLLAVALCL
WIAPQLKGYQPAVPLLSVSFILLLAGELIGRGVFYGLHMTVGMAVAS
>SEQF1516_EDU85238.1 aspartate transaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTPVLTSVKKAEQYLLENETTKNYLGIDGIPEFGRCTQE
LLFGKGSALINDKRARTAQTPGGTGALRIAADFLAKNTSVKRVWVSNPSWPNHKSVFNSADLEVREYAYYDAENHTLDFD
ALINSLNEAQAGDVVLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFARGLEEDAEGLRAFAAMHKELIV
ASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMKAAIRANYSNPPAHGASVVATILSNDALRAIWEQELTDMRQRIQR
MRQLFVNTLQEKGANRDFSFIIKQNGMFSFSGLTKEQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAIVAVL
>SEQF1516_EDU85239.1 3-deoxy-D-manno-octulosonate cytidylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCAFSDDTVIVNVQGDEPMIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
PWDRDRFAKGLETVGDNFLRHLGIYGYRAGFIRRYVTWQPSPLEHIEMLEQLRVLWYGEKIHVAVAHEVPGTGVDTPEDL
ERVRAEMR
>SEQF1516_EDU85240.1 cytidylate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLALAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEV
ILEGEDVSGEIRTQEVANAASQVAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRML
QLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQYARQKLALA
>SEQF1516_EDU85241.1 thioredoxin-disulfide reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEI
IFDHINKVDLQNRPFRLNGDNGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
EALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGL
FVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADA
K
>SEQF1516_EDU85242.1 tetraacyldisaccharide 4'-kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRAPVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVG
VVSRGYGGKAESYPLLLSADTTTAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVE
IVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNLRTGTRCDVAQLEHVVAMAGIGH
PPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALVSTGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLAQ
LTSLASGN
>SEQF1516_EDU85243.1 formate acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFLAGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVAS
TITSHDAGYINKALEKVVGLQTEAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRC
RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKYAQFTSLQADLENGVNLEQTIRLREEIAEQHRALGQMKEMAAK
YGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMSFGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLR
TPEYDELFSGDPIWATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVSIDTSSLQY
ENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGGVDEKLKMQVGPKSEPIKGDLLNYDEVMERM
DHFMDWLAKQYITALNIIHYMHDKYSYEASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEI
EGEYPQFGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGRRAGAPFGPGANPMHGR
DQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVRKTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAM
ENPEKYPQLTIRVSGYAVRFNSLTKEQQQDVITRTFTQSM
>SEQF1516_EDU85244.1 putative fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKSVLTAFITVVCATSSVMAADDNAITDGSVTFNGKVIAPACTLVAATKDSVVTLPDVSATKLQTNGQVSGVQTDVPIE
LKDCDTTVTKNATFTFNGTADTTQITAFANQASSDAATNVALQMYMNDGTTAIKPDTETGNILLQDGDQTLTFKVDYIAT
GKATSGNVNAVTNFHINYY
>SEQF1516_EDU85245.1 fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRIIWILFLLGLTGGCELFAHDGTVNISGSFRRNTCVLAQDSKQINVQLGDVSLTRFSHGNYGPEKSFIINLQDCGTDV
STVDVTFSGTPDGVQSEMLSIESGTDAASGLAIAILDDAKILIPLNQASKDYSLHSGKVPLTFYAQLRPVNSDVQSGKVN
ASATFVLHYD
>SEQF1516_EDU85246.1 integration host factor, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIEIRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHF
KPGKELRDRANIYG
>SEQF1516_EDU85247.1 pyruvate formate-lyase 1-activating enzyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVIGRIHSFESCGTVDGPGIRFITFFQGCLMRCLYCHNRDTWDTHGGKEVTVEDLMKEVVTYRHFMNASGGGVTASGGE
AILQAEFVRDWFRACKKEGIHTCLDTNGFVRRYDPVIDELLEVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAKYLANK
NVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELGKHKWVAMGEEYKLDGVKPPKKETMERVKGILEQY
GHKVMF
>SEQF1516_EDU85248.1 putative DNA recombination-associated ATPase RarA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVER
ISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVY
LLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEI
AGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDC
FTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYA
AGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>SEQF1516_EDU85249.1 lipid A export permease/ATP-binding protein MsbA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFMLSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGI
TSYVSSYCISWVSGKVVMTMRRRLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMM
FYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVLIFGGQEVETKRFDKVSNRMRLQ
GMKMVSASSISDPIIQLIASLALAFVLYAASFPSVMDSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFT
ILDSEQEKDEGKRVIERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRFYDIDEGEI
LMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQIEEAARMAYAMDFINKMDNGLDTVIGENGVL
LSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERG
THNDLLEHRGVYAQLHKMQFGQ
>SEQF1516_EDU85250.1 3-phosphoshikimate 1-carboxyvinyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNLLDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGG
PLHAEGALELFLGNAGTAMRPLAAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGG
NVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQHYQQFVVKGGQSYQSPGTYLVE
GDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRFADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIAT
AALFAKGTTTLRNIYNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFSLVALSDTP
VTILDPKCTAKTFPDYFEQLARISQAA
>SEQF1516_EDU85251.1 hypothetical protein ECH7EC4501_2990 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIMPPQKTLSMGENTRISQRRYYRFILLIHNANAEEMINLI
>SEQF1516_EDU85252.1 DNA translocase FtsK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFG
VMAYTIPVIIVGGCWFAWRHQSSDENIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHS
SGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARIL
RGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPV
AVAAAATTATQSWAAPVEPVTQTPPVASVDVPPSQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQYNEPLQQP
VQPQQPYYAPAAEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPE
PVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATL
ATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYND
DEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMK
ALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQQVAPQPQYQQPQQPVAPQQQYQQPQQPVAP
QPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARL
VEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVY
LREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKML
ELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQH
PVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSR
TILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDP
LFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLSPPPFD
>SEQF1516_EDU85253.1 carbon storage regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHREEIYQRIQAEKSQQSSY
>SEQF1516_EDU85254.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGKRISREKLTIKKMIDLYQAKCPQASAEPEHYEALFVYAQKRLDKCVFGEEKPACKQCPVHCYQPAKREEMKQIMRWA
GPRMLWRHPILTVRHLIDDKCPVPELPEKYRPKKPRE
>SEQF1516_EDU85255.1 carbohydrate kinase, FGGY family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDADTAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGL
GSIRCCRALLKADGTPAAPLISWQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKSWAWSED
AAVMEKFNIPRHMLFDVQMPGTVLGQITPQAALATHFPAGLPVVCTTSDKPVEALGAGLLDDETAVISLSTYIALMMNGK
ALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSWLRDMLGESLIQDARAQDLSPEDLLNKKASCVPPGCNGLMTVLDW
LTNPWEPYKRGIMIGFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFADVFNLPAR
RNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKALTKHTDVILKKSYEVMHGEL
GNADSIQSWSNA
>SEQF1516_EDU85256.1 sorbitol-6-phosphate 2-dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQEINAEYGEGTAYGFGADATSEQSVLALSRGVDEIFV
RVDLLVYSAGIAKAAFISDFQLGDFDRSLQVNLVGYFLCAREFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFG
GVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLGIKPDQVEQYYIDKVPLKRGCDYQDVLNMLLFYASP
KASYCTGQSINVTGGQVMF
>SEQF1516_EDU85257.1 putative ferredoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVARNLWRAADAPHIVPADSVERQMVQRLINACPVGLFSLTPEGDLRVDYHGCLECGTCRLLCDESTLQQWRYPPSGFG
ITYRFG
>SEQF1516_EDU85258.1 protein RecA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQV
IAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVG
SETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEI
EKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
>SEQF1516_EDU85259.1 PTS system, glucitol/sorbitol-specific, IIA component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVIYQTTITRIGASATDALSDQMLITFREGAPADLEEYCFIHCHGELKGALHPGLQFTLGQHRYPVTAVGSVAEDNLRE
LGHVTLRFDGLNEAEFPGTVHVAGPVPDDIAPGSVLKFESVKE
>SEQF1516_EDU85260.1 electron transfer flavoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNILLAFKAEPDAGMLAEKEWQAAAHGNSGPDISLLRSLLGADEQAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYL
MALGFEEAVLLETAADLRFASEFVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDAPFI
TLEQRTEHGLRCCRIRLPAVIAVRQCGEVALPVPGMRQRMAAGKAEIIRKTVAAELPAMQCLQLARAEQRRGATLIDGQT
VAEKAQKLWQDYLRQRMQP
>SEQF1516_EDU85261.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPMLIYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMD
GKLRYSIVFTLMTVGIMFGALFMWLLG
>SEQF1516_EDU85262.1 DNA mismatch repair protein MutS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYL
AKLVNQGESVAICEQIGDPATSKGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEP
ADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCAAGCL
LQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRV
LLERQQTIGALQDFTAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQALREKMGEF
AELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRG
QSHLAPINYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAE
RAYTLNYTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYIGSYV
PAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILHNATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIK
ALTLFATHYFELTQLPEKMEGVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELESIS
PNADATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV
>SEQF1516_EDU85263.1 cell division protein FtsB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNAKLKARNDQLFAEIDDLNGGQEALEERARNELSMTRP
GETFYRLVPDASKRAQSAGQNNR
>SEQF1516_EDU85264.1 FAD binding domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHGIYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPR
TGASATEGGLETVVENSVVLDGSAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRS
IGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITEVTVKIFKFTPENNLFYGYILED
MKTGFNILREIMVEGYRPSIARLYDAEDGTQHFTHFADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIE
TWFNNLNWGPDKVAAERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQNGTNMYFV
YDYNVVNCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWSKLEHGSAWALLEGLKKQFDPNGIMNTGTIY
PIEK
>SEQF1516_EDU85265.1 hypothetical protein ECH7EC4501_6003 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALHSVKPKFSRYTQLQPDFIVVDSVNANAVKRVHGIA
>SEQF1516_EDU85266.1 sulfate adenylyltransferase, subunit 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVMLHLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTA
KAYGCELLVHQNPEGVAMGINPFVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP
KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLERDGMLMMIDDNRIDLQPGEVIK
KRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVSTTSERQGRVIDRDQAGSMELKKRQGYF
>SEQF1516_EDU85267.1 hypothetical protein ECH7EC4501_5927 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIIISLQDDKTAVEYRKGSFFALSKTTLLRKIADLS
>SEQF1516_EDU85268.1 alkaline phosphatase isozyme conversion peptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFFPGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSR
YIYTARDNRKNWHNVTGSTVIAAHEGKAPQQIIIMAHLDTYAPQSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKN
TPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGVKTPEAVRKLTRDRALAIARSHG
IAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSVEATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRLDNQQHIDKALP
GRIERRCRDVMRIMLPLVKELAKAS
>SEQF1516_EDU85269.1 alanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGMNQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLEN
VGYTARHHTFFEMLGNFSFGDYFKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDN
KGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQFNRQADGTMEPLPKPSVDTGMG
LERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDLSNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRH
GNMLGAKETFFYKLVGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDGETAFRLYD
TYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMIRVDSASEFKGYDHLELNGKVTALFVDGKAV
DAINAGQEAVVVLDQTPFYAESGGQVGDKGELKGANFSFVVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARI
RLNHSATHLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNLPIETNIMDLEAAKAKG
AMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRIISESGTAAGVRRIEAVTGEGAITTVHADSDRLSEVAHL
LKGDSNNLADKVRSVLERTRQLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLGST
IIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTDAAALPAALASVKGWVSAKLQ
>SEQF1516_EDU85270.1 competence/damage-inducible protein CinA domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDSELMQLSEQVGQALKARGATVTTAESCTGGWVAKVITDIAGSSAWFERGFVTYSNEAKAQMIGVREETLAQHGAVSE
PVVVEMAIGALKAARADYAVSISGIAGPDGGSEEKPVGTVWFAFATARGEGITLRECFSGDRDAVRRQATAYALQTLWQQ
FLQNT
>SEQF1516_EDU85271.1 multifunctional protein SurE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNSLTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALM
RPRPDIVVSGINAGPNLGDDVIYSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVDEGYVSITPLHVDLTAHSAQDVV
SDWLNSVGVGTQW
>SEQF1516_EDU85272.1 carbamoyltransferase HypF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGWTGYAIHDGGNNSMAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGDGVEVRLLEDPETFLVQLHQH
CPPLARIDSVEREPFIWSQLPTEFTIRQSAGGAMNTQIVPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAM
PYDRPFTVMAAFPLCPACDKEYRDPLDRRFHAQPVACPECGPYLEWVSHGEHAEQEAALQAAIAQLKMGNIVAIKGIGGF
HLACDARNSNAVATLRARKHRPAKPLAVMLPVADGLPDAARQLLTTPAAPIVLVDKKYVPELCDDIAPGLNEVGVMLPAN
PLQHLLLQELQCPLVMTSGNLSGKPPAISNEQALEDLQGIADGFLIHNRDIVQRMDDSVVRESGEMLRRSRGYVPDALAL
PPGFKNVPPVLCLGADLKNTFCLVRGEQVVLSQHLGDLSDDGIQTQWREALRLMQNIYNFTPQYVVHDAHPGYVSCQWAS
EMNLPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGENGALWGGECLRVNYRECEHLGGLPAVALPGGDLAAK
QPWRNLLAQCLRFVPEWQNYPETASVQQQNWSVLARAIERGINAPLASSCGRLFDAVAAALGCAPATLSYEGEAACALEA
LAASCDGVTHPVTMPRVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGFAALMREQATMRGITTLVFSGGVIHNRLL
RARLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAARWLAGEVQNG
>SEQF1516_EDU85273.1 4-hydroxybenzoate decarboxylase, subunit D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MICPRCADEQIEVMAKSPVKDVWTVYQCQHCLYTWRDTEPLRRTSREHYPEAFRMTQKDIDDAPMVPSIPPLLAEGKR
>SEQF1516_EDU85274.1 sulfate adenylyltransferase, subunit 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLAL
LVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGI
KHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSESMPWYSGPTLLEVLETVEIQRV
VDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQRVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISR
GDLLLAADEALPAVQSASVDVVWMAEQPLSPGQSYDIKIAGKKTRSRVDGIRYQVDINNLTQREVENLPLNGIGLVDLTF
DEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSAFELELNALVRRHFPHWGARDLLGEK
>SEQF1516_EDU85275.1 hypothetical protein ECH7EC4501_5996 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSIIVLSFRIYCFITKRQPNLIRLKDLKCYFDRKMKDKYFNLKV
>SEQF1516_EDU85276.1 sulfite reductase (NADPH) hemoprotein, beta-component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGFKGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAM
LLRCRLPGGVITTKQWQAIDKFAGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSN
PYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKTTVVIPPQNDIDLHANDMNFVAI
AENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGYLPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFK
AEVERRAGIKFEPIRPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRITANQNLII
AGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCP
NGCGRAMLAEVGLVGKAPGRYNLHLGGNRIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRP
VLDPARDLWD
>SEQF1516_EDU85277.1 regulatory protein RecX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKNGPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIA
SRSRKGYGPARIRQELNQKGISREATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDI
WRNFAD
>SEQF1516_EDU85278.1 CRISPR-associated protein Cas5 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGVGIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTV
QMPKEVRKARYFSRREELSAPDLLSAIISRRDYYTDAWWMVAVATTPDAPYSLEQLQDGLRHPVFPLYLGRKSHPLALPL
APLLLEGNASDVLRNAYQQYQDSFRELKVSLPKLQDECWWEGEHDGLVASKILRRRDVPLNRQQWLFGERTINQGPWLSK
EEPCTSQE
>SEQF1516_EDU85279.1 oxidoreductase, short chain dehydrogenase/reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIENQGVEVDFMQVDITAEGA
PQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGG
QWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVLDHIPANRWGDTQDLMGAAVFLA
SQASNYVNGHLLVVDGGYLVR
>SEQF1516_EDU85280.1 phosphoadenosine phosphosulfate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKLDLNALNELPKVDRILALAETNAQLEKLDAEGRVAWALDNLPGEYVLSSSFGIQAAVSLHLVNQIRPDIPVILTDTG
YLFPETYRFIDELTDKLKLNLKVYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQ
SGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKNGLKYHPLWDEGYLSVGDTHTTRKWEPGMAEEETRFFGLKRECG
LHEG
>SEQF1516_EDU85281.1 CRISPR-associated protein, Cse2 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIVKEEHKATLRKWHEELQEKRGERASLRRSTTVNDVCLTDGFRLFLKNRQIKWQDEPEWRITALALIAALSANVKAID
ERLPFAAQLAAVMSKGRFTRLSAVKTPDELLRQLRRVVRLLNGSVNLDSLAEGVFRWCQESDDLLNHHRRHQRPTEFIRI
RWALEYYQAGDVDNEQNQ
>SEQF1516_EDU85282.1 formate hydrogenlyase, subunit G [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNLLGPRDANGIPVPMTVDESIASMKASLLKKIKRSAYVYRVDCGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHAD
ILLFTGAVTRAMRSPALRAWQSAPDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATLYGFAMAL
GLLEQKIHARGPGEQDEQPAEILHGDMVQPLRVKVDREARRLAGYRYGRQIADDYLTQLGQGEEQVARWLEAENDPRLNE
IVSHLNHVVEEARIR
>SEQF1516_EDU85283.1 hypothetical protein ECH7EC4501_5961 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPELIISGEEANGEFLMLVPGKMLFCSFCVMLMKQVRKIVSVG
>SEQF1516_EDU85284.1 serine/threonine-protein phosphatase 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPSTRYQKINTHHYRHIWVVGDIHGEYQLLQSRLHQLSFFPETDLLISVGDNIDRGPESLNVLRLLNQPWFISVKGNHEA
MALDAFATGDGNMWLASGGDWFFDLNDSEQKEATDLLLKFHHLPHIIEITNDNIKYVIAHADYPGSEYLFGKEIAESELL
WPVDRVQKSLNGELQQINGADYFIFGHMMFDNIQTFANQIYIDTGSPKSGRLSFYKIK
>SEQF1516_EDU85285.1 lytic murein transglycosylase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKRRYVTLLPLFVLLAACSSKPKPTETETTTGTPSGGFLLEPQHNVMQMGGDFANNPNAQQFIDRMVNKHGFDRQQLQE
ILSQAKRLDSVLRLMDNQAPTTSVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIG
VETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFAGAMGYGQFMPSSYKQYAVDFSG
DGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMANGQAPGLPNGFKTRYSISQLAAAGLTPQQPLGNHQQASLLRLDVG
TGYQYWYGLPNFYTITRYNHSTHYAMAVWQLGQAVALARVQ
>SEQF1516_EDU85286.1 major facilitator family transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSNTEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITS
AMIITGLLGLLMATYPPLWVMLCIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFS
RFAPDDSTSLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVLRISTTWYCSMVIFGVFTIYAIL
SYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPLGGIITTYSKVKSPTRVIQILSVLGLLALTALLVTNSNPQSVAMG
IGLILLLGFTCYASRGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTQPAAEAYRNMWLMGMAALAM
VIVFTFLLFQKIRTADSAPAMASSK
>SEQF1516_EDU85287.1 tRNA pseudouridine synthase D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHILVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKD
KHAVTEQWLCARVPGKEMPDLSAFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYF
GAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQVVDGDALQLAGRGSWFVATTEE
LVELQRRVNDKELMITAALPGSGEWGTQREALAFEQAAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEI
RFWLPAGSFATSVVRELINTTGDYAHIAE
>SEQF1516_EDU85288.1 hydrogenase expression/formation protein HypD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGHTHAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRID
TCVEIASHPAVIFCTFGDAMRVPGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
AKARDVQNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDFQRPLVVAGFEPLDLLQGVVMLV
EQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCVNGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPR
ARCGEVLTGKCKPHQCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQESEA
>SEQF1516_EDU85289.1 4-hydroxybenzoate decarboxylase, subunit B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLIVGMTGATGAPLGVALLQALREMPNVETHLVMSKWAKTTIELETPYSARDVAALADFSHNPADQAATISSGSFRTDG
MIVIPCSMKTLAGIRAGYADGLVGRAADVVLKEGRKLVLVPREMPLSTIHLENMLALSRMGVAMVPPMPAFYNHPETVDD
IVHHVVARVLDQFGLEHPYARRWQGLPQARNFSQENE
>SEQF1516_EDU85290.1 formate hydrogenlyase, subunit B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEKESAPQLCHHCEDAPCAVVCPVNAITRVDGAVQLNES
LCVSCKLCGIACPFGAIEFSGSRPLDIPANANTPKAPPAPPAPARISTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCP
TKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK
>SEQF1516_EDU85291.1 4-hydroxybenzoate decarboxylase, subunit C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFDDLRSFLQALDDHGQLLKISEEVNAEPDLAAAANATGRIGDGAPALWFDNIRGFTDARVAMNTIGSWQNHAISLGLP
PNTPVKKQIDEFIRRWDNFPIAPERRANPAWAQNTVDGDEINLFDILPLFRLNDGDGGFYLDKACVVSRDPLDPDNFGKQ
NVGIYRMEVKGKRKLGLQPVPMHDIALHLHKAEERGEDLPIAITLGNDPIITLMGATPLKYDQSEYEMAGALRESPYPIA
TAPLTGFDVPWGSEVILEGVIESRKREIEGPFGEFTGHYSGGRNMTVVRIDKVSYRTRPIFESLYLGMPWTEIDYLMGPA
TCVPLYQQLKAEFPEVQAVNAMYTHGLLAIISTKKRYGGFARAVGLRAMTTPHGLGYVKMVIMVDEDVDPFNLPQVMWAL
SSKVNPAGDLVQLPNMSVLELDPGSSPAGITDKLIIDATTPVAPDNRGHYSQPVVDLPETKAWAEKLTAMLAARK
>SEQF1516_EDU85292.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGQLTCCSQVNVQLLYDVNRQTNSTGLVHNRPFNRLANLPGCVC
>SEQF1516_EDU85293.1 formate hydrogenlyase, subunit D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVLYPLIQALVLFAVAPLLSGITRVARARLHNRRGPGVLQEYRDIIKLLGRQSVGPDASGWVFRLTPYVMVGVMLTIAT
ALPVVTVGSPLPQLGDLITLLYLFAIARFFFAISGLDTGSPFTAIGASREAMLGVLVEPMLLLGLWVAAQVASSTNISNI
TDTVYHWPLSQSIPLVLALCACAFATFIEMGKLPFDLAEAEQELQEGPLSEYSGSGFGVMKWGISLKQLVVLQMFVGVFI
PWGQMETFTVGGLLLALVIAIVKLVVGVLVIALFENSMARLRLDITPRITWAGFGFAFLAFVSLLAA
>SEQF1516_EDU85294.1 pyridine nucleotide-disulphide oxidoreductase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNLSGGRLYTHALAELLPQFHLTAPLERRITHESLSLLT
PDCATTFSSLQPGGESWSVLRARFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRARYVVLAEGANSVL
AERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGAFLYTNQQTLSLGIVCPLSSLTQ
SRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVPEGGLHSMPVQYAGNGWLLVGDALRSCVNTGISVRGMDTALTGAQ
AAAQTLISACQHREPQNLFPLYHHNVERSLLWDVLQRYQHVPVLLQRPGWYRTWPALMQDISRDLWDQGDKPVPPLRQLL
WRHLRRHGLWNLAGDVIRSVRCL
>SEQF1516_EDU85295.1 hydrogenase nickel insertion protein HypA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGGDMHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSLAFCFDLVCRGSVAEGCKLHLEEQEAECWCETC
QQYVTLLTQRVRRCPQCHGDMLQIVADDGLQIRRIEIDQE
>SEQF1516_EDU85296.1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVYALLAHPRVKRVVIAISPGDSRFAQLPLANHPQITVVD
GGDERADSVLAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGL
WHALTPQFFPRELLHDCLTRALNEGAAITDEASALEYCGFHPQLVEGRADNIKVTRPEDLALAEFYLTRTIHQENT
>SEQF1516_EDU85297.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTWEKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIG
RQGYTARHVVITGGEPCIHDLLPLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKH
PVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHKYLNIA
>SEQF1516_EDU85298.1 hypothetical protein ECH7EC4501_5939 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVFVTVLVTVYPRWRGEHTKHTYLFLNKFIPHQQSTN
>SEQF1516_EDU85299.1 formate hydrogenlyase maturation protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKVVFSQLSRKFIDENDATPAEAQQVVYYSLAIGHHLGVIDCLEAALTCPWDEYLAWIATLEAGSEARRKMEGVPKYG
EIVIDINHVPMLANAFDKARAAQTSQQQEWSTMLLSMLHDIHQENAIYLMVRRLRD
>SEQF1516_EDU85300.1 CRISPR-associated protein Cas2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIWQQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVD
LDGLRLVSFLPVDNQ
>SEQF1516_EDU85301.1 formate hydrogenlyase regulatory protein HycA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHHAMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYY
VETKDGEDKQRIAQAQLSIDGMIDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPAA
>SEQF1516_EDU85302.1 sulfite reductase [NADPH] flavoprotein, alpha-component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVLNQQPAALAATPAPAAEMPGITIISASQTGNARRVAE
ALRDDLLTAKLNVKLVNAGDYKFKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEF
FCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSVATGVVNEIHTSPYSKDAPLVAS
LSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDALGVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFE
LTVNTANIVENYATLTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIASSQEEVENE
VHVTVGVVRYDVEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADEAP
GKNWLFFGNPHFTEDFLYQVEWQRYVKEGVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAK
DVEQALLEVIAEFGGMDTEAADEFLSELRVERRYQRDVY
>SEQF1516_EDU85303.1 gutQ protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGKVVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEAL
HGDLGMIESRDVMLFISYSGGAKELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNT
LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASVMDAMLELSRTGLGLVAVCDAQQ
QVQGVFTDGDLRRWLVGGGALTTPVNEAMTVGGTTLQSQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGI
I
>SEQF1516_EDU85304.1 formate hydrogenlyase, subunit F [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEQNPQQCIGCAACVNACPSNALTVETDLATGELAWEFNLGRCIFCGR
CEEVCPTAAIKLSQEYELAVWKKEDFLQQSRFALCNCRVCNRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR
QKCLVPSDRIELTRHMKEAI
>SEQF1516_EDU85305.1 anaerobic nitric oxide reductase flavorubredoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEKNVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHA
EEDHAGALTELMAQIPDTPIYCTANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDA
VLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNLPVDMIATSHGVVWRDNPTQIVE
LYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGIAETDPRVAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREH
GREIARQWALAPLPQSTVNTVVKEETSATTTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGTPWSEVPDNFLCPECSLGK
DVFDELASEAK
>SEQF1516_EDU85306.1 glycerol-3-phosphate responsive antiterminator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTISQIVKKIKNAGKYAFIHVDLLEGASNKEVVIQFLKLV
TEADGIISTKASMLKAARAEGFFCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVC
DEEDARNAINAGVVALSTTNTGVWTLAKKLL
>SEQF1516_EDU85307.1 protein-L-isoaspartate O-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSRRVQALLDQLRAQGIQDEQVLNALAAVPREKFVDEAFEQKAWDNIALPIGQGQTISQPYMVARMTELLELTPQSRVL
EIGTGSGYQTAILAHLVQHVCSVERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMT
QLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA
>SEQF1516_EDU85308.1 transcriptional regulator AscG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQYTALIACKGMKMMTTMLEVAKRAGVSKATVSRVLSGNGYVSQETKDRVFQAVEESGYRPNLLARNLSAKSTQTLGLVV
TNTLYHGIYFSELLFHAARMAEEKGRQLLLADGKHSAEEERQAIQYLLDLRCDAIMIYPRFLSVDEIDDIIDAHSQPIMV
LNRRLRKNSSHSVWCDHKQTSFNAVAELINAGHQEIAFLTGSMDSPTSVERLAGYKDALAQHGIALNEKLIANGKWTPAS
GAEGVETLLERGAKFSALVASNDDMAIGAMKALHKRGVAVPEQVSVIGFDDIAIAPYIVPALSSVKIPVTEMIQEIIGRL
IFMLDGGDFSPPKTFSGKLIRRDSLIALSR
>SEQF1516_EDU85309.1 hydrogenase maturation peptidase HycI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDVLLCVGNSMMGDDGAGPLLAEKCAAAPKGNWVVIDGGSAPENDIVAIRELRPTRLLIVDATDMGLNPGEIRIIDPDD
IAEMFMMTTHNMPLNYLIDQLKEDIGEVIFLGIQPDIVGFYYPMTQPIKDAVETVYQRLEGWEGNGGFAQLAVEEE
>SEQF1516_EDU85310.1 hydrogenase isoenzymes nickel incorporation protein HypB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCTTCGCGEGNLYIEGDEHNPHSAFRSAPFAPAARPKMKITGIKAPEFTPSQTEEGDLHYGHGEAGTHAPGMSQRRMLEV
EIDVLDKNNRLAERNRARFAACKQLVLNLVSSPGSGKTTLLTETLMRLKDSVPCAVIEGDQQTVNDAARIRATGTPAIQV
NTGKGCHLDAQMIADAAPRLPLDDNGILFIENVGNLVCPASFDLGEKHKVAVLSVTEGEDKPLKYPHMFAAASLMLLNKV
DLLPYLNFDVEKCIACAREVNPEIEIILISATSGEGMDQWLNWLETQRCA
>SEQF1516_EDU85311.1 hydrogenase expression/formation protein HypE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLAQLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGT
ANDVAVSGAIPRYLSCGFILEEGLPMETLKAVVTSMAETARTAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPTNIHWG
AQTLTAGDILLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKALRDATRGGVNAVVHEFAAACGC
GIEISESALPVKPAVRGVCELLGLDALNFANEGKLVIAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGV
KRTLDLPHAEPLPRIC
>SEQF1516_EDU85312.1 anaerobic nitric oxide reductase transcription regulator NorR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIA
RAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
LLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVD
VRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRQGLSRVVLSAGARNLLQHYSF
PGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEVAAVPVVKQNLREATEAFQRETIRQALAQNHHNWA
ACARMLETDVANLHRLAKRLGLKD
>SEQF1516_EDU85313.1 CRISPR-associated protein, Cse1 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADLQGAAWQFLLGLLQSSFAPKDYRRWDDIWEDGLEAEK
LREALLSLEHPFQFGPDSPSFMQDFEVLMGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCSHCSALALFSLQLNA
PSGGKGYRTGLRGGGPMTTLIELQEYQGNQQAPLWRKLWLNVMPQDEADLPLPKKFDDLVFPWLGPTRTSELAGAVVTDD
QVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQSDALLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGL
IWRDWLGLIETGKSENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHHFPLLLNKKEGQIPKLRLAAQT
ASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIEEGQDADELLGKWQKEIWLFARQDFDERVFT
NPYEPVDLERVMTARKKYFTTSAEKQSAKAAREKKQEAAE
>SEQF1516_EDU85314.1 CRISPR-associated protein, Cse3 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYLSRITLHTGQLSPAQLLHLVDRGEYVMHQWLWDLFPGGKERQFLYRREELQGAFRFFVLSQERPAESETFTIECRSFV
PELRTGQQLCFNLRANPTICKAGKRHDLLMEAKRQVRGQAEGSDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQ
LRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEV
>SEQF1516_EDU85315.1 nitric oxide reductase FlRd-NAD(+) reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNGIVIIGSGFAARQLVKNIRKQDASIPLTLIAADSMDEYNKPDLSHVISQGQRADDLTRQTAGEFAEQFNLLLFPQTW
VTDIDAEARVVKSQNNQWQYDKLVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDF
CRAGKMVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILATLDHQRSIEVDAVIAATGLRPE
TALARRAGLTINRGVCVDSYLQTSNADIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPEL
PLHLAGETQRQDLRWQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPV
>SEQF1516_EDU85316.1 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHALTDALLGAAALGDIGKLFPDTDPAFKGADSRELLREA
WRRIQAKGYTLGNVDVTIIAQAPKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK
>SEQF1516_EDU85317.1 CRISPR-associated helicase Cas3 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKYPLSLLKDKNIVTFFDFWGKTRRGEKEGGDGYHLLCWHSLDVAAMGYLMVKRNCFGLADYFRQLGISDKEQAAQFFA
WLLCWHDIGKFARSFQQLYLAPELKIPEGSRKNYEKISHSTLGYWLWNYYLSECEELLPSSSLSSRKLTRVIEMWMSITT
GHHGRPPDRIDELDNFLPEDKAAARDFLLEIKALFPLIEIPTFWDDDEGVELLKQLSWYISATVVLADWTGSSTRFFPRV
AHPMDIKDYWQKTLVQAQNALTVFPPKAETAPFTGINTLFPFIEHPTPLQQKVLDLDISQPGPQLFILEDVTGAGKTEAA
LILAHRLMAARKAQGLFFGLPTMATANAMYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQ
TFSQGCAAWFANSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYMSCILEGLIERQARGGN
SVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWLTHVTKSDVNSHRVATRKDVERSVSVGWLHSEQESIARI
ESAVSQGKCIAWIRNSVDDAIKVHRQLLARGVIPASSLSLFHSRFAFSDRQRIEMETLARFGKEDGSQRAGKVLICTQVL
EQSVDCDLDEMISDLAPVDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILAPVWDDAPGDEWFGSAMRNSAYVYP
DHGRIWLTQRVLREQGAIQMPHAARLLIESVYGEDVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFKPGYAANINDYLP
EKLSTRLAEESVSLWLATCIAGVVKPYATGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRQWCIEQRQDPEMANVILV
TDDESCGYSAREGLIGKVD
>SEQF1516_EDU85318.1 CRISPR-associated protein Cas1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGE
AGVRVYSSGQPGGARADKLLYQAKLALTEDLRLKVVRKMYELRFREPPPARRSVDQLRGIEGSRVRQTYALLAKQYGVKW
NGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPAIGFIHSGKPLSFVYDIADIIKFDSVVPKAFEIAARQP
AEPDKEVRLACRDIFRSTKLTGKLIPLIEKVLAAGEIEPPQPAPDMLPPAIPEPETLGDSGHRGRGG
>SEQF1516_EDU85319.1 formate hydrogenlyase, subunit E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKESLSMSEEKLGQHYLAALNEAFPGVVLDHAWQTKDQLTVTVKVNYLPEVVEFLYYKQGGWLSVLFGNDERKLNGHYA
VYYVLSMEKGTKCWVTVRVEVDANKPEYPSVTPRVPAAVWGEREVRDMYGLIPVGLPDERRLVLPDDWPDELYPLRKDSM
DYRQRPAPTTDAETYEFINELGDKKNNVVPIGPLHVTSDEPGHFRLFVDGENIIDADYRLFYVHRGMEKLAETRMGYNEV
TFLSDRVCGICGFAHSTAYTTSVENAMGIQVPERAQMIRAILLEVERLHSHLLNLGLACHFTGFDSGFMQFFRVRETSMK
MAEILTGARKTYGLNLIGGIRRDLLKDDMIQTRQLAQQMRREVQELVDVLLSTPNMEQRTVGIGRLDPEIARDFSNVGPM
VRASGHARDTRADHPFVGYGLLPMEVHSEQGCDVISRLKVRINEVYTALNMIDYGLDNLPGGPLMVEGFTYIPHRFALGF
AEAPRGDDIHWSMTGDNQKLYRWRCRAATYANWPTLRYMLRGNTVSDAPLIIGSLDPCYSCTDRMTVVDVRKKKSKVVPY
KELERYSIERKNSPLK
>SEQF1516_EDU85320.1 hypothetical protein ECH7EC4501_6001 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKVEKRLTDLSGALAHNYPEIKLTKYRHQLQRVLTAGLVTEKWE
>SEQF1516_EDU85321.1 4Fe-4S binding domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRIHVIKGVNISTATVCRQCEDAPCANVCPNGAISRDKG
FVHVMQERCIGCKTCVVACPYGAMEVVVRPVIRNSGAGLNVRADKAEANKCDLCNHREDGPACMAACPTHALICVDRNKL
EQLSAEKRRRTALMF
>SEQF1516_EDU85322.1 formate hydrogenlyase transcriptional activator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYTPMSDLGQQGLFDITRTLLQQPDLASLCEALSQLVKRSALADNAAIVLWQAQTQRASYYASREKDTPIKYEDETVLA
HGPVRSILSRPDTLHCSYEEFCETWPQLAAGGLYPKFGHYCLMPLAAEGHIFGGCEFIRYDDRPWSEKEFNRLQTFTQIV
SVVTEQIQSRVVNNVDYELLCRERDNFRILVAITNAVLSRLDMDELVSEVAKEIHYYFDIDDISIVLRSHRKNKLNIYST
HYLDKQHPAHEQSEVDEAGTLTERVFKSKEMLLINLHERDDLAPYERMLFDTWGNQIQTLCLLPLMSGDTMLGVLKLAQC
EEKVFTTTNLNLLRQIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVLKQVEMVAQ
SDSTVLILGETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDLFGHERGAFTGASAQRIGRFELADKSSLFLD
EVGDMPLELQPKLLRVLQEQEFERLGSNKIIQTDVRLIAATNRDLKKMVADREFRSDLYYRLNVFPIHLPPLRERPEDIP
LLAKAFTFKIARRLGRNIDSIPAETLRTLSNMEWPGNVRELENVIERAVLLTRGNVLQLSLPDIALPEPETPPAATVVAQ
EGEDEYQLIVRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMKRLGIDKSALI
>SEQF1516_EDU85323.1 hypothetical protein ECH7EC4501_5969 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVLIIPAVNNVDDVEMTRRHGDEIHQNLKNRFNNNKLKVGTKNA
>SEQF1516_EDU85324.1 adenylylsulfate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTVAGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDA
DRKENIRRVGEVANLMVEAGLVVLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFT
GIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS
>SEQF1516_EDU85325.1 glucitol operon repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILEHAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKEL
IAEAAVGFIHDGDSIILDAGSTVLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
FEHFTFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNVVCSLESVDKLITDADIDPAFRQ
ALEEKGIDVIITGESNE
>SEQF1516_EDU85326.1 formate hydrogenlyase, subunit C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAISLINSGVAWFVAAAVLAFLFSFQKALSGWIAGIGGAVGSLYTAAAGFTVLTGAVGVSGALSLVSYDVQISPLNAIW
LITLGLCGLFVSLYNIDWHRHAQVKCNGLQINMLMAAAVCAVIASNLGMFVVMAEVMALCAVFLTSNSKEGKLWFALGRL
GTLLLAIACWLLWQRYGTLDLRLLDMRMQQLPLGSDIWLLSVIGFGLLAGIIPLHGWVPQAHANASAPAAALFSTVVMKI
GLLGILTLSLLGGNAPLWWGIALLVLGMITAFVGGLYALMEHNIQRLLAYHTLENIGIILLGLGAGVTGIALEQPALIAL
GLVGGLYHLLNHSLFKSVLFLGAGSVWFRTGHRDIEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEWVIYQSFFK
LSNSGAFVARLLGPLLAVGLAITGALAVMCMAKVYGVTFLGAPRTKEAENATCAPLLMSVSVVALAICCVIGGVAAPWLL
PMLSAAVPLPLEPANTTVSQPMITLLLIACPLLPFIIMAICKGDRLPSRSRGAAWVCGYDHEKSMVITAHGFAMPVKQAF
APVLKLRKWLNPVSLVPGWQCEGSALLFRRMALVELAVLVVIIVSRGA
>SEQF1516_EDU85327.1 CRISPR-associated protein, Cse4 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSLKRAWRTSALFEQALAGHIGIRSGRIAREAATILIEK
GIEEKKAIEWAAKIADYLGKAKNDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLALLRKDRMAVD
IAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGETGFGSALFYTYICIDKDLLVEN
LGGDEALANQTLRAFTEAALKVSPTGKQNSFASRAYASWALAEKGTEQPRSLAAAFYEPINGTRQLDVAVQRITTLRENM
NTVYEQKTECASFDVMNKQGSMKDVLDFICA
>SEQF1516_EDU85328.1 transcriptional regulator, MarR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLRNKAFHQLRQLFQQHTARWQHELPDLTKPQYAVMRAIADKPGIEQVALIEAAVSTKATLAEMLARMENRGLVRREHD
AADKRRRFVWLTAEGEKILAAAIPIGDSVDEEFLGRLSAEEQELFVQLVRKMMNT
>SEQF1516_EDU85329.1 hypothetical protein ECH7EC4501_5982 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSHVIVTSVDDIFFPALQKLISLNNSKLKTGMICECIGALTVIAGEFDEPFHHC
>SEQF1516_EDU85330.1 PTS system, arbutin-, cellobiose-, and salicin-specific, EIIBC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNYAALARSVIAALGGVDNISAVTHCMTRLRFVIKDDALIDSPTLKTIPGVLGVVRSDNQCQVIIGNTVSQAFQEVVS
LLPGDMQPALPVGKPKLTLRRIGAGILDALIGTMSPLIPAIIGGSMVKLLAMILEMSGVLTKGSPTLTILNVIGDGAFFF
LPLMVAASAAIKFKTNMSLAIAIAGVLVHPSFIELMAKAAQGEHVEFALIPVTAVKYTYTVIPALVMTWCLSYIERWVDR
ITPAVTKNFLKPMLIVLIAAPLAILLIGPIGIWIGSAISALVYTIHGYLGWLSVAIMGALWPLLVMTGMHRVFTLTIIQT
IAETGKEGMVMPSEIGANLSLGGSSLAVAWKTKNPELRQTALAAAASAIMAGISEPALYGVAIRLKRPLIASLISGFICG
AVAGMAGLASHSMAAPGLFTSVQFFDPANPMSIVWVFAVMALAVVLSFILTLLLGFEDIPVEEAAAEARKHQSAQPTVAK
EVSLN
>SEQF1516_EDU85331.1 hydrogenase assembly chaperone HypC/HupF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCIGVPGQIRTIDGNQAKVDVCGIQRDVDLTLVGSCDENGQPRVGQWVLVHVGFAMSVINEAEARDTLDALQNMFDVEPD
VGALLYGEEK
>SEQF1516_EDU85332.1 queuosine biosynthesis protein QueD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLE
NPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRGE
>SEQF1516_EDU85333.1 lipoprotein NlpD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAPAHTNSGMLITPPPKMGTTSTAQQPQIQPVQQPQIQA
TQQPQIQPVQPVAQQPVQMENGRIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVG
QTLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSANKMLPNNKPTATTVTAPVTVPT
ASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASEGGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHND
DYLSAYAHNDTMLVREQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR
>SEQF1516_EDU85334.1 6-phospho-beta-glucosidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVFPEGFLWGGALAANQSEGAFREGGKGLTTVDMIPHGEHRMAVKLGLEKRFQLRDDEFYPSHEATGFYHRYKEDIALM
AEMGFKVFRTSIAWSRPFPQGDELTPNQQGIAFYRSVFEECKKYGIEPLVTLCHFDVPMQLVTEYGSWRNRKLVEFFSRY
ARTCFEAFDGLVKYWLTFNEINIMLHSPFSGAGLVFEEGENQDQVKYQAAHHQLVASALATKIAHEVNPQNQVGCMLAGG
NFYPYSCKPEDVWAALEKDRENLFFIDVQARGAYPAYSARVFREKGVTIDKAPGDDEILKNTVDFVSFSYYASRCASAEM
NTNNSSAANVVKSLRNPYLQVSDWGWGIDPLGLRITMNMMYDRYQKPLFLVENGLGAKDELAANGEINDDYRISYLREHI
RAMGEAIADGIPLMGYTTWGCIDLVSASTGEMSKRYGFVFVDRDDAGNGTLTRTRKKSFWWYKKVIASNGEDLE
>SEQF1516_EDU85335.1 glucitol operon activator protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSALITVAVIAWCAQLALGGWQISRFNRAFDTLCQQGRVGVGRSSGRFKPRVVVAIALDDQQRIADTLFMKGLTVFARP
QKIPAITGMHAGDLQPDVIFPHDPLSQNALSLALKLKRG
>SEQF1516_EDU85336.1 hypothetical protein ECH7EC4501_0108 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPRYLWSKKKPALSGAGFFLCFLYASARTVTCGNGNGDGGGDGGGNGGANAFHGCCVLCNFYLSVRYAYIG
>SEQF1516_EDU85337.1 phosphopentomutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEADNGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNA
EVIGAYAWAHEMSSGKDTPSGHWEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEH
MKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIGDKAGNFQRTGNRHDLAVEPPAP
TVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKATGLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAA
GLELFDRRLPELMSLLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLAKYFGTSDM
EYGKAMF
>SEQF1516_EDU85338.1 putative ferredoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACPAGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQ
WEYPRGTFGVEFRYG
>SEQF1516_EDU85339.1 DNA repair protein RadA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEVRLAASPTVARNERLSGYAGSAGVAKVQKLSDISLEELPRFSTG
FKEFDRVLGGGVVPGSAILIGGNPGAGKSTLLLQTLCKLAQQMKTLYVTGEESLQQVAMRAHRLGLPTDNLNMLSETSIE
QICLIAEEEQPKLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMVGHVTKDGSLAGPKVLEHCIDCS
VLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQGLREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDH
SMMANPRRVAVGLEQNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQDLVVFGEV
GLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKAPEGMQIFGVKKLSDALSVFDDL
>SEQF1516_EDU85340.1 soluble lytic murein transglycosylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKAKQVTWRLLAAGVCLLTVSSVARADSLDEQRSRYAQIKQAWDNRQMDVVEQMMPGLKDYPLYPYLEYRQITDDLMNQ
PAVTVTNFVRANPTLPPARTLQSRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWNTGQSEEAWQGAKELWLTGK
SQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGQMPADYQTIASAIISLANNPNTVLTFARTTGATDF
TRQMAAVAFASVARQDAENARLMIPSLAQAQQLNEDQIQELRDIVAWRLMGNDVTDEQAKWRDDAIMRSQSTSLIERRVR
MALGTGDRRGLNTWLARLPMEAKEKDEWRYWQADLLLERGREAEAKEILHQLMQQRGFYPMVAAQRIGEEYELKIDKAPQ
NVDSALTQGPEMARVRELMYWNLDNTARSEWANLVKSKSKTEQAQLARYAFNNQWWDLSVQATIAGKLWDHLEERFPLAY
NDLFKRYTSGKEIPQSYAMAIARQESAWNPKVKSPVGASGLMQIMPGTATHTVKMFSIPGYSSPGQLLDPETNINIGTSY
LQYVYQQFGNNRIFSSAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAYYRYFMGDKPTLMSATE
WGRRY
>SEQF1516_EDU85341.1 protein FixC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKNVTGGRLYAHSLEHIIPGFAESAPVERLITHEKLAFM
TEKSAMTMDYCNGDETSPSQRSYSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
GVNSILAEKLGMAKRVKPTNVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTDGLMGGGFLYTNENTLSLGLVCG
LHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEYSAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLA
IAAGEAAAKTVLSAMKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFTIDGSAPEL
MRKKILRHGKKVGFINLIKDGMKGVTVL
>SEQF1516_EDU85342.1 sensor protein CreC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIGMRLLLGYFLLVAVAAWFVLAIFVKEVKPGVRRATEGTLIDTATLLAELARPDLLSGDPTHGQLAQAFNQLQHRPFR
ANIGGINKVRNEYHVYMTDAQGKVLFDSANKAVGQDYSRWNDVWLTLRGQYGARSTLQNPADPESSVMYVAAPIMDGSRL
IGVLSVGKPNAAMAPVIKRSERRILWASAILLGIALVIGAGMVWWINRSIARLTRYADSVTDNKPVPLPELGSSELRKLA
QALESMRVKLEGKNYIEQYVYALTHELKSPLAAIRGAAEILREGPPPEVVARFTDNILTQNARMQALVETLLRQARLENR
QEVVLTAVDVAALFRRVSEARTVQLAEKNITLHVMPTEVNVAAEPALLEQALGNLLDNAIDFTPKSGRITLSAEVDQEHV
ALKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSEVARLFNGEVTLRNVQEGGVLASLRLHRHFT
>SEQF1516_EDU85343.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASIAVESGVPEQPFGSEETRAGARNRVANARRLLPEADFWVAIEAGID
GDSTFSWVVIENTTQRGEARSATLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRASVYHQAVIL
ALSPFHNAVY
>SEQF1516_EDU85344.1 chaperone protein DnaJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAEAKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMG
GGGFGGGADFSDIFGDVFGDIFGGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPAGVDTGDRIRLAGEGEAGEHGAP
AGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAALGGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGD
LLCRVVVETPVGLNEKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR
>SEQF1516_EDU85345.1 RNA methyltransferase, TrmH family, group 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRITIILVAPARAENIGAAARAMKTMGFSELRIVDSQAHLEPATRWVAHGSGDIIDNIKVFPTLAESLHDVDFTVATTAR
SRAKYHYYATPVELVPLLEEKSSWMSHAALVFGREDSGLTNEELALADVLTGVPMVADYPSLNLGQAVMVYCYQLAILIQ
QPTKSDTTADQHQLQALRERAMALLTTLAVADDIKLVDWLQQRLGLLEQRDTAMLHRLLHDIEKNITK
>SEQF1516_EDU85346.1 chaperone protein DnaK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDE
EVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYL
VEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPL
KVALQDAGLSVSDIDDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLG
IETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDA
DGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPAD
DKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDDDVVDAEFEEVKDKK
>SEQF1516_EDU85347.1 thymidine phosphorylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAMTIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGP
IVDKHSTGGVGDVTSLMLGPMVAACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSL
APADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSEALAEAIVGVANGAGVRTTALLT
DMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVTMALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQ
KGPTDFVENYAKYLPTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQVDGQRPLA
VIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE
>SEQF1516_EDU85348.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPPQISTLMRISDKLAGINAARFHDWQPDFTPENARQAI
LAFKGDVYTGLQAETFSEDDFDFAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRFIIENRLTKPEQLTGFNSEGYFF
DEASSSNGELVFKRYEQR
>SEQF1516_EDU85349.1 carnitine operon protein caiE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLRGDYGRLIVQAGANIQDGCIMHGYTDTDTIVGENGHI
GHGAILHGCVIGRDALVGMNSVIMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
DLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR
>SEQF1516_EDU85350.1 right origin-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKSAVALRLTARPILDIALQY
RFDSQQTFTRAFKKQFAQTPALYRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMR
YQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVMLQGGEYVMFTYEGLGTGVQEFI
LTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRPINLRCELLIPIRR
>SEQF1516_EDU85351.1 peptide chain release factor 3 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYH
DCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVEN
ELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNE
FDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRV
VSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNFAPELFRR
IRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVARLKSEYNVEAVYESVNVATARWVECADAK
KFEEFKRKNESQLALDGGDNLAYIATSMVNLRLAQERYPDVQFHQTREH
>SEQF1516_EDU85352.1 chaperone/peptidyl-prolyl cis-trans isomerase SurA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDGLMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQII
LQMGQKMGVKISDEQLDQAIANIAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIAHSADQQALNGGQMGWGRIQELP
GIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGESKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTT
FAAAAKEFSQDPGSANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAAQKDRAYRM
LMNRKFSEEAASWMQEQRASAYVKILSN
>SEQF1516_EDU85353.1 putative crotonobetaine/carnitine-CoA ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELNQEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWF
GLAKIGAIMVPINARLLREESAWILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQ
PATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYLTVMPAFHIDCQCTAAMAAFSAG
ATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTLMVQPPSANDRQHRLREVMFYLNLSEQEKDTFCERFGVRLLTSYG
MTETIVGIIGDRPGDKRRWPSIGRAGFCYDAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAKVLEADGWL
HTGDTGYRDEEGFFYFIDRRCNMIKRGGENVSCVELENIIATHPKIQDIVVVGIKDSIRDEAIKAFVVLNEGETLSEEEF
FRFCEQNMAKFKVPSYLEIRKDLPRNCSGKIIRKNLK
>SEQF1516_EDU85354.1 aerobic respiration control protein ArcA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGKNGLLLARELREQANVALMFL
TGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYK
LPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDTPEIIATIHGEGYRFCGDLED
>SEQF1516_EDU85355.1 dihydrodipicolinate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSLLGSDAGELAGAGKTGVTVQSSLDAIKDDFDVFIDFT
RPEGTLNHLAFCRQHGKGMVIGTTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVGEHTAMFADIGERLEITHKASSR
MTFANGAVRSALWLSGKENGLFDMRDVLDLNNL
>SEQF1516_EDU85356.1 amino acid carrier protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFGKSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGV
ALAITAGGPGAVFWMWVAAFIGMATSFAECSLAQLYKERDVNGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSG
VQANAVARALSFSFDFPPLVTGIILAVFALLAIIRGLHGVARLMQGFVPLMAIIWVLTSLVICVINIGQLPHVIWSIFES
AFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMGSTPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILL
AGNGTTYMPLEGIQLIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNNPKAIWCLRICTFATVIGG
TLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVRPVFDPLRYPDIGRQLSRDAWDDVSQE
>SEQF1516_EDU85357.1 inner membrane protein CreD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKSPLFWKMTTLFGAVLLLLIPIMLIRQVIVERADYRSDVEDAIRQSTSGPQKLVGPLIAIPVTELYTVQEEDKTVERK
RSFIHFWLPESLMVDGNQNVEERKIGIYTGQVWHSDLTLKADFDVSRLSELDAPNITFGKPFIVISVGDARGIGVVKAPE
VNGTALTIEPGIGLEQGGQGVHIPLPEGDWRKQNLKLNMALNLSGTGDLSVVPAGRNSEMTLTSNWPHPSFLGDFLPAKR
EVSESGFQAQWQSSWFANNLGERFASGNDTGWENFPAFSVAVTTPADQYQLTDRATKYAILLIALTFMAFFVFETLTAQR
LHPMQYLLVGLSLVMFYLLLLALSEHTGFTVAWIIASLIGALMNGIYLQAVLKGWRNSMLFTLALLLLDGVMWGLLNSAD
SALLLGTSVLVVALAGMMFVTRNIDWYAFSLPKMKASKEVTTDDELRIWK
>SEQF1516_EDU85358.1 putative type-1 fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKYIIPFVATTLMFSATTFAKDVDQGTLTIRGEVVDTTCYFVNGDSTTDIVVEDVVTSAMNQLINNEIYTLKTGSTSHD
LEIQCDGNTAPSIEVLASEFDANNFTLNKGTAENIGFAIFLDDGTLTRMRPGLKTPLKDNGSGQYFLNLNAQYARTSGNP
VTKGSVESTVTIKISAD
>SEQF1516_EDU85359.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKMQSIVLALSLVLVAPMATQAAEITLVPSVKLQIGDRDNRGYYWDGGHWRDHGWWKQHYEWRGNRWHPHGPPPPPRHH
KKAHHDHHGGHGPGKHHR
>SEQF1516_EDU85360.1 homoserine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVESAETFSLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQI
PVAMTLEKNMPIGSGLGSSACSVVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQPELAAKLMKDVIAEPYRERLLP
GFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTAQRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN
>SEQF1516_EDU85361.1 protein FixA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRG
PDELIVVIDDQFEQALPQQTASALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAAWSEQQVAAPKQRERQRIVIEGD
GEEQIAAFAENLRKVI
>SEQF1516_EDU85362.1 nicotinamide-nucleotide adenylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPSAQKLEALHRFLGLEFPRQKKTIGVVFGKFYPLHTGH
IYLIQRACSQVDELHIIMGFDDTRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNG
IKKFMAEKGIQPDLIYTSEEADAPQYMEHLGIETVLVDPKRTFMSISGAQIRENPFRYWEYIPTEVKPFFVRTVAILGGE
SSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDEIALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCK
KYEGREHPFVQALIDEYRFDLVILLENNTPWVVDGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEEDYDSRFLRCVE
LVREMMGEQR
>SEQF1516_EDU85363.1 phosphoglycerate mutase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRL
RELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
>SEQF1516_EDU85364.1 transcriptional activatory protein CaiF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNTLTYILSEVTEISCEVKMIPNKLEGRGCQCQRLVKVV
DIDEQIYARLRNNSREKLVGVRKTPRIPAVPLTELNREQKWQMMLSKSMRR
>SEQF1516_EDU85365.1 phospholipase, patatin family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGQRIPVTLGNIAPLSLRPFQPGRIALVCEGGGQRGIFTAGVLDEFMRAQFNPFDLYLGTSAGAQNLSAYICNQPGYARK
VIMRYTTKREFFDPLRFVRGGNLIDLDWLVEATASQMPLQMDTAARLFDSGKSFYMCACRQDDYAPNYFLPTKQNWLDVI
RASSAIPGFYRSGVSLEGINYLDGGISDAIPVKEAARQGAKTLVVIRTVPSQMYYTPQWFKRMERWLGDSSLQPLVNLVQ
HHETSYRDIQQFIEKPPGKLRIFEIYPPKPLHSIALGSRIPALREDYKLGRLCGRYFLATVGKLLTEKAPLTRHLVPVVT
PESIVIPPAPVANDTLVAEVSDAPQANDPTFNNEDLA
>SEQF1516_EDU85366.1 FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASLSEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQ
YFSRREFMDAGEPEIGAIMLFTAMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA
>SEQF1516_EDU85367.1 electron transfer flavoprotein, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTFSQVWVFSDTPSRLPELMNGAQALANQINAFVLNDADGAQAIQLGANHVWKLNGKPDDRMIEDYASVMADTIRQHGA
DGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEH
ERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR
>SEQF1516_EDU85368.1 sodium/proton antiporter nhaA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHLHRFFSSDASGGIILIIAAILAMMMANSGATSGWYHDFLETPVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVK
RELMQGSLASLRQAAFPVIAAIGGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTAVLKSGVHATLAGVIVGFFIPLK
EKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSLQGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLP
EGTTYQQIMAVGILCGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV
>SEQF1516_EDU85369.1 transcriptional regulatory protein CreB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARQQVPDVMILDVGLPDISGFELCRQLLALHPALPVLF
LTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLRRVKKFSTPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEF
LLLKTLLKSPGRVWSRQQLMDIVWEDAQDTYDRTVDTHIKTLRAKLRAINPDLSPINTHRGMGYSLRSL
>SEQF1516_EDU85370.1 osmotically inducible protein Y [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTMTRLKISKTLLAVMLTSAVATGSAYAENNAQTTNESAGQKVDSSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISV
KTDQKVVTLSGFVESQAQAEEAVKVAKGVEGVTSVSDKLHVRDAKEGSVKGYAGDTATTSEIKAKLLADDIVPSRHVKVE
TTDGVVQLSGIVDSQAQSDRAESIAKAVDGVKSVKNDLKTK
>SEQF1516_EDU85371.1 crotonobetainyl-CoA:carnitine CoA-transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIENVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGRE
AFLKLMETTDIFIEASKGPAFARRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
MPAFPYTADYFSGLTATTAALAALHKARETGKGESIDIAMYEVMLRMGQYFMMDYFNGGEMCPRMSKGKDPYYAGCGLYK
CADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPEGTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACA
KVLTVPELESNPQYVARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDIQELVSKGL
AKVED
>SEQF1516_EDU85372.1 ribosomal protein S20 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDKAAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLT
AQINKLA
>SEQF1516_EDU85373.1 creA protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYKHLILSLSLIMLGPLAHAEEIGSVDTVFKMIGPDHKIVVEAFDDPDVKNVTCYVSRAKTGGIKGGLGLAEDTSDAAI
SCQQVGPIELSDRIKNGKAQGEVVFKKRTSLVFKSLQVVRFYDAKRNALAYLAYSDKVVEGSPKNAISAVPVMPWRQ
>SEQF1516_EDU85374.1 major facilitator family transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYILVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKV
GRRKMFLIDIIAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFGEPVAFDEEQPQQTRFRDLFNRR
HFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMT
LALAVLGLIPDMGIWLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPIFINNYGIS
NTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG
>SEQF1516_EDU85375.1 gram-negative pilus assembly chaperone [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIITALLMSFFILPVHAGVVIYGTRIIYPEKNREVLVQLMNQSKNASLIQAWIDDGNTTIAPEKIQVTFILTPPVSRVA
GGSGQQLKIRKMPNNLPHNKESLFYLNVLDIPPNNPQNAGKNKIKLALQNRIKLLWRPSGIAPVDKKSLSQLNIKKKNNA
ISINNETANWITVTTIKAQNVKVNNESILLPPFSHNDITLKNNHASEYELTVVDDYGNNIHSKIAAR
>SEQF1516_EDU85376.1 putative Hok/gef family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQHKVMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE
>SEQF1516_EDU85377.1 molybdopterin biosynthesis protein Mog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPAR
RDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFA
SVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE
>SEQF1516_EDU85378.1 5-nucleotidase YjjG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQAVNKPLWVDYQNGAITSLQLQHGRFESWAERLNVEPG
KLNEAFINAMAEICTPLPGAVSLLNAIRGNAKIGIITNGFSALQQVRLERTGLRDYFDLLVISEEVGVAKPNKKIFDYAL
EQAGNPDRSRVLMVGDTAESDILGGINAGLATCWLNAHHREQPEGIAPTWTVSSLHELEQLLCKH
>SEQF1516_EDU85379.1 glutathione-regulated potassium-efflux system ancillary protein kefF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILIIYAHPYPHHSHANKRMFEQARTLEGVEIRSLYQLYPDFNIDIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDK
VFSHGWAYGHGGTALHGKHLLWAVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
RHYKQRLLEWQEAHHG
>SEQF1516_EDU85380.1 hypothetical protein ECH7EC4501_0141 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHEPQNNIKNPAIKLTFSAHISRMPPFARNSSVSRFALIYVIIVN
>SEQF1516_EDU85381.1 radical SAM domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSRCALVSKIIPFSCVDGPGSRLALFLQGCNLRCKNCHNPWTMGRCNDCGECVPQCPHQALQIVDGKVVWNAVVCEQCD
TCLKRCPQHATPMAQSMSVDEVLSHVRKAVLFIEGITVSGGEATTQLPFVVALFTAIKNDPQLRHLTCLVDSNGMLSETG
WEKLLPVCDGAMLDLKAWGSECHQQLTGRDNQQIKRSICLLAERGKLAELRLLVIPGQVDYLQHIEELAAFIKGVGDVPV
RLNAFHAHGVYGEAQSWASATPEDVEPLADALRERGVSRLIFPALYL
>SEQF1516_EDU85382.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPGSLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRN
KPKDRLTPLLEAPDADELLNWLRRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVAEEYSIAFGHWASLEGKGTPEGI
YALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGEGEAVAS
>SEQF1516_EDU85383.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAKRTTQSVTVTVDRELVNRARDAGLNMSATLTVALNAELKKHAATRWREENAEAIAALNQLADETGCFSDEYRSF
>SEQF1516_EDU85384.1 riboflavin biosynthesis protein RibF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGRKRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLR
YLAECGVDYVLCVRFDRRFAALTAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQVSPVKGVYAVEVLGLGEKPLPGV
ANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVLRKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA
>SEQF1516_EDU85385.1 membrane protein, GPR1/FUN34/yaaH family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIFYGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLV
AILLMPKLGLTDAPNAQFLGVYLGLWGVFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
GASAIYLAMGEVLNEQFGRTVLPIGESH
>SEQF1516_EDU85386.1 hydrolase, TatD family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MICRFIDTHCHFDFPPFIGDEEASLQRAAQAGVGKIIVPATEAENFARVQALAENYQPLYAALGLHPGMLEKHSDVSLDQ
LQQALERRPAKVVAVGESGLDLFGDDPQFERQQWFLDEQLKLAKRYDLPVILHSRRTHDKLAMHLKRHDLSRTGVVHGFS
GSLQQAERFVQLGYKIGVGGTITYPRASKTRVVIAKLPLASLLLETDAPDMPLNGFQGQPNRPEQAARVFDVLCELRPEP
EDEIAEVLLNNTYAVFNVRG
>SEQF1516_EDU85387.1 transcriptional activator protein NhaR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSMSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEERLQGKLFKRKGRGLEPSELGELVYRYADKMFTLS
QEMLDIVNYRKESNLLFDVGVADVLSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQE
GLFSVRIGECGVSFWCTNPPPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEILGEFDDAALMKAFGAMHNAI
FVAPTLYAYDFYADKTVVEIGRVENVMEEYHAIFAERMIQHPAVQRICNTDYSALFSPAVR
>SEQF1516_EDU85388.1 phosphoserine phosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKQRLTQYQSKLGAAMVIVAAWCVEDYQVIRLA
GSLTARATRLAHEAQLDVAPLGKIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEMVAEVTERAMRGELDFTASLRS
RVATLKGADANILQQVRENLPLMPGLTQLVLKLETLGWKVAIASGGFTFFAEYLRDKLRLTAVVANELEIMDGKFTGNVI
GDIVDAQYKAKTLTRLAQEYEIPLAQTVAIGDGANDLPMIKAAGLGIAYHAKPKVNEKAEVTIRHADLMGVFCILSGSLN
QK
>SEQF1516_EDU85389.1 signal peptidase II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFPSLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGIS
VTLVVMMYRSKATQKLNNIAYALIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
AKKQ
>SEQF1516_EDU85390.1 4-hydroxythreonine-4-phosphate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLTDRAAMLGLPLTLRPYSPNSPAQPQTTGTLTLLPVAL
RESVTAGQLAIENGHYVVETLARACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHMGTEEIDTIIPVLDELRAQGMKL
NGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQGFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNL
AIKMIVNTQ
>SEQF1516_EDU85391.1 L-carnitine/gamma-butyrobetaine antiporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLG
NEPPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFLWGPLPWATYSFLSVAFAYF
FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWI
ILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVSGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFY
WAWWVIYAIQMSIFLARISRGRTVRELCFGMVMGLTASTWILWTVLGSNTLLLIDKNIINIPNLIEQYGVARAIIETWAA
LPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIAGG
CPLFFVNIMVTLSFIKDAKQNWKD
>SEQF1516_EDU85392.1 deoxyribose-phosphate aldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTAAICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGN
DDIEIALAETRAAIAYGADEVDVVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIK
AGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAIADELFGADWADARHYRFGASSL
LASLLKALGHGDGKSASSY
>SEQF1516_EDU85393.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHFHEKWASSFPFMPKVMRHCKKFRDVHFDPDAFATTDAFI
>SEQF1516_EDU85394.1 purine nucleoside phosphorylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITD
FGVKKIIRVGSCGAVLPHVKLRDVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLF
YSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAERQTTFNDMIKIALESVLLGDKE
>SEQF1516_EDU85395.1 carbamoyl-phosphate synthase, large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEK
ERPDAVLPTMGGQTALNCALELERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAA
DVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAM
GIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIA
KVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALR
GLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVG
ITGLNAEFLRQLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDRE
KIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIV
QYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAVDRLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVL
GGRAMEIVYDEADLRRYFQTAVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPAYT
LSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKATGVPLAKVAARVMAGKSLAEQGVT
KEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDL
AAKLLKQGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIRRSALQYKVHY
DTTLNGGFATAMALNADATEKVISVQEMHAQIK
>SEQF1516_EDU85396.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIDLENQEREIINLMFSQRISWLAAVRIRHKLSLAEVSKMLGISINSLKQIEKTERLSSNIKSKMAEIYGCPPELLICPS
WMTAEHK
>SEQF1516_EDU85397.1 threonine synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEIDEMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAF
AFPAPVANVESDVGCLELFHGPTLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISRLLAQICYYFEAVAQLPQEARNQ
LVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVNDTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKI
WQLKELGYAAVDDETTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGETLDLPKEL
AERADLPLLSHNLPADFAALRKLMMNHQ
>SEQF1516_EDU85398.1 hypothetical protein ECH7EC4501_0131 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDGISTSPHCLYKSNIVDDVIINKTRQNELVKVFCEYKTEFLILFDDFFRSQDLPKPSPVLHHFFQYTHLRDAHFYRCK
LIEHTVQFSFFKHKGITLLRLDVFDDRTSECLSEEIKIYQECHEKFIKFLKANFNQEIYPELYTPEIFYEACRNLQSFYD
HQETSQNAKYSAIVKKKSYFNKEIRNLIKKNIYPELYNEQCNKIPASSTDDNQKITWQNFKTSNAAYSQLCEKLSLLKSS
PSRLIEKSAYCSNENMITDKFDVVFSYCGDNVKEFILLLPYNKSLEMHELNEQNIQYLTALNINIHKLLLSNITIEKSNL
SYGYYFGCVLSNISCFESDLSNTIFSNGEINNLFIKKSNIFGTSFTNTMIKNLRCEDIMPGRWTTQLVNKHLGYRYTGVF
KTLASIDDKPSRFEILIPLVQTLVRDNVKLNNDVYKELKKFMHDYDKTSPEMRKYLQSINESMFLMKKISHQD
>SEQF1516_EDU85399.1 hypothetical protein ECH7EC4501_0144 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRFEAIKQGHIKIVDISIVCNFTVDKCELNPAYVIKNIDSPKDLLNGQKKRSSSENRISYSIKLADEKYPP
>SEQF1516_EDU85400.1 nonspecific ribonucleoside hydrolase RihC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEKTTRNALQLLHFWNAEIPLAQGAAVPLVRAPRDAASV
HGESGMAGYDFVEHNRKPLGIPAFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTP
NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLSTLPQLNRTGKMLHALFSHYRSGSMQSGLRMHDLCAIAW
LVRPDLFTLKPCFVAVETQGEFTSGTTVVDIDGCLGKPANVQVALDLNVKGFQQWVAEVLALVP
>SEQF1516_EDU85401.1 CcdB protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQFTVYRSRSRNAAFPFVIDVTSDIIGVINRRIVIPLTPIERFSRIRPPERLNPILLLVDGKEYVLMTHETATVPVNALG
TKFCDASAHRTLIKGALDFMLDGI
>SEQF1516_EDU85402.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLMRNELFKSMEGHPEQHRRNWQLIAGELQHFGGDSIAN
KLRGHGKLYRAILLDVSKRLKLKADKEMSTFEIEQQLLEQFLRNTWKKMDEEHKQEFLHAVDARVNELEELLPLLMKDKL
LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSSYRVTIPAVLQIACLRRMVSATQV
>SEQF1516_EDU85403.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLFEIEVSSCTGNNTNCNSVRFNFNLNTILQVNLMTCGFEDQSIDTGLFVLSRINNENYQFHHIRFDCIQGEQGELVFEP
SDVEYYFEPVTIQESGTSILKNELENSEDGAGQIGFQLSNDGTNEIQYGKSNYYSFQHPHEGSNQIPLFIRPRTYGNNVS
SGQIMSRVKIVVMYN
>SEQF1516_EDU85404.1 hypothetical protein ECH7EC4501_0078 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLVSLFMGRKRP
>SEQF1516_EDU85405.1 dimethyladenosine transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEIGPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPF
LGPKLTIYQQDAMTFNFGELAEKMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAFNQRRKTIRNSLGNLFSVEVLTG
MGIDPAMRAENISVAQYCQMANYLAENAPFQES
>SEQF1516_EDU85406.1 fimbrial usher protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRTTRWVAAIIFLYSFPGYAEETFDTHFMIGGMKGEKVSEYHFDNKQPLPGNYELDFYVNNQWRGKQDITIPESPVKPC
LPKVLLTKLGVKTGNLNTEDNCILLDKAVHGGQYQWDISEHRLNLTVPQAYINELERGYVPPESWDRGIDAFYTSYNLSQ
YRSYDSNNNSNTASYGRFNSGLNLFSWQLHSDASYSKPDDMKGTWQSNTLYLEHGWSQILSTVQIGENYTSSLIFDSLRF
SGIRLFRDMQMLPDSMQSFTPLVQGVAQSNALITVSQNGYIIYQKEVPPGPFTIADLQLSGSGSDLDVSIKEADGSVRSF
LVPYSSVPNMLQPGISNFDFIAGRSKIYGVKNQEDFLEANYIYGLNNLLTLYGGTILSDNYNAITLGNGWNTPLGAISFD
ATRSSSKLNNDITHEGTSYQVAYNKYLVQTATRFSVAAWRYASQDYRTFSDHLYENDKINHQSDYDDFYDIGRKNSLSAN
IMQPLSNNLGNVSLSALWRNYWGRSGNAKDYQFSYSNSWQRISYTFSASQSYDENDKEEERFNLFISIPFYWGDDIAKTR
HQINLSNSTSFSKDGYSSNNTGITGIAGEHDQLNYGIYVNQQQQNNDTSLGTNLSWRTPIATIDGSYSHSKNAWQSGGSI
SSGLVVWPGGINITNQLSDTFAILDAPGLEGAHINGQKYNRTNSKGQVVYDLMIPHRENHLVLDTANSESETELQGNRQI
IAPYRGAVSYVQFTTDQRKPWYIQALRPDGSPLTFGYDVLDLQENNIGVVGQGSRLFIRVDEIPTGIKVALNDEQNLFCT
ITFQHVIDENKTYICQ
>SEQF1516_EDU85407.1 crotonobetainyl-CoA dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVKALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRL
GAPTYVLYQLPGGFNTFLREGTQEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELDEKDMFGREGNGFNRVKEEFDHE
RFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRFQLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYF
CANAAFEVVDSAMQVLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR
>SEQF1516_EDU85408.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSVFTISASLAISLMLCCTAQANDHKLLGVIAMPRNETNALALKLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSAS
QSLNIPSEIKEGQTTDWININSDNDNKRCVSKITFSGHTVNSSDMATLKIIGDD
>SEQF1516_EDU85409.1 carbamoyl-phosphate synthase, small subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILTDPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGL
VIRDLPLIASNFRNTEDLSSYLKRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
EVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTIVPAQTSAEDVLKMNPDGIFLSN
GPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLALASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEAT
LPANLRVTHKSLFDGTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK
>SEQF1516_EDU85410.1 transaldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISSGQTGYIPLTSCLKRNTIMTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQIPEYRKLIDDAVAWA
KQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLSYDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQG
IRAAEQLEKEGINCNLTLLFSFAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGYE
TVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARITESEFLWQHNQDPMAVDKLAEGI
RKFAIDQEKLEKMIGDLL
>SEQF1516_EDU85411.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAGKSTLLRIMAGIDKDIEGEARPQPDIKIGYLPQEPQL
NPEHTVRESIEEAVSEVVNALKRLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKI
ANLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHDRYFLDNVAGWILELDRGEGIPW
EGNYSSWLEQKDQRLAQEASQEAARRKSIEKELEWVRQGTKGRQSKGKARLARFEELNSTEYQKRNETNELFIPPGPRLG
DKVLEVSNLRKSYGDRLLIDDLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQEQPDSGTITLGETVKLASVDQFRDSMDN
SKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGERGRLHLAKLLQVGGNMLLLDEPTNDLDIETL
RALENALLEFPGCAMVISHDRWFLDRIATHILDYQDEGKVEFFEGNFTEYEEYKKRTLGADALEPKRIKYKRIAK
>SEQF1516_EDU85412.1 protein ApaG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQLLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEY
QYTSGAIIETPLGTMQGHYEMIDENGVPFSIDIPVFRLAVPTLIH
>SEQF1516_EDU85413.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRYVVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAV
RNEAKSRDLTVFDATCPLVTKVHMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVLVVGSKNSSNSNRLAELAQRMGK
RAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQNVVARLQQLGGGEAIPLEGREENIVFEVPKELRVDIREVD
>SEQF1516_EDU85414.1 glutathione-regulated potassium-efflux system protein KefC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDSHTLVQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPWGLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLW
KLRAAVFGGGALQMVICGGLLGLFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAI
PLVAMIPLLAASSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREVFSAVALFLVFGFGLLLEEVGLS
MAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLFFIGVGMSIDFGTLIENPLRIVILLLGFLIIKIAMLWLIARPLQV
PNKQRRWFAVLLGQGSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREADEIDEEQP
RVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDLLESAGAAKAEVLINAIDDPQTNLQL
TEMVKEHFPHLQIIARARDVDHYICLRQAGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAM
VENDTKARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS
>SEQF1516_EDU85415.1 trp operon repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLTPDEREALGTRVRIVEELLRGEMSQRELKNELGAGIA
TITRGSNSLKAAPVELRQWLEEVLLKSD
>SEQF1516_EDU85416.1 carnitinyl-CoA dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRQGTTLPANNHALKQYAFFAGMLSSLKKQKWRKGMSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDD
PQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADN
ASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMTGRRMGAEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAI
AALKEIYRTTSEMPVEESYSYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR
>SEQF1516_EDU85417.1 protein smp precursor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARTKLKFRLHRAVIVLFCLALLVALMQGASWFSQNHQRQRNPQLEELARTLARQVTLNVAPLMRTDSPDEKRIQAILDQ
LTDESRILDAGVYDEQGDLIARSGESVEVRDRLALDGKKAGGYFNQQIVEPIAGKNGPLGYLRLTLDTHTLATEAQQVDN
TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEESEKKECPITTRKEIVMSTLRLLISDSYDPWF
NLAVEECIFRQMPATQRVLFLWRNADTVVIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEY
DKTISTSIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLSRLANYLNPDKKKLAAK
GITSVRSRVTNLTELLPGIPHEQVCEAITEAFFAHYGERVEAEIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLL
DERFSWGGVELHFDVEKGHITRAQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPDQEKELRELSTWIAGA
VR
>SEQF1516_EDU85418.1 dihydrofolate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDSPAEYKIFLNIILAPVDDGLRFTYSGDNFFYREISMISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMG
RHTRESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQFLPKAQKLYLTHIDAEVEGDT
HFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR
>SEQF1516_EDU85419.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFFDELKTSLEEAVEIKQGLKKPARVARHEIEDAKAVVDRKRCSRRIRHSVLNA
>SEQF1516_EDU85420.1 4-aminobutyrate transaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNNEFHQRRLSATPRGVGVMCNFFAQSAENATLKDVEGNEYIDFAAGIAVLNTGHRHPDLVAAVEQQLQQFTHTAYQIV
PYESYVTLAEKINALAPVSGQAKTAFFTTGAEAVENAVKIARAHTGRPGVIAFSGGFHGRTYMTMALTGKVAPYKIGFGP
FPGSVYHVPYPSDLHGISTQDSLDAIERLFKSDIEAKQVAAIIFEPVQGEGGFNVAPKELVAAIRRLCDEHGIVMIADEV
QSGFARTGKLFAMDHYADKPDLMTMAKSLAGGMPLSGVVGNANIMDAPAPGGLGGTYAGNPLAVAAAHAVLNIIDKESLC
ERAMQLGQRLTKTLIDAKENVPAIAAVRGLGSMIAAEFNDPQTGEPSAAIAQKIQQRALAQGLLLLTCGAYGNVIRFLYP
LTIPDAQFDAAMKILQDALRD
>SEQF1516_EDU85421.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKVFTPEEREKIKGQVVELVRLSGRETLRALEAKTGASRYYISTLARELVASGDVYNSGYGLFPSEQARKDWQNARKKL
SRAKVKKPVVVDPDLIWSLPDGEIRRYDRRLNIICSECRKSEAMQRVLAFYQGNFQKVLL
>SEQF1516_EDU85422.1 phosphatidylglycerophosphatase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRSIARRTAVGAALLLVMPVAVWISGWRWQPGEQSWLLKAAFWVTETVTQPWGVITHLILFGWFLWCLRFRIKAAFVLFA
ILAAAILVGQGVKSWIKDKVQEPRPFVIWLEKTHHIPVDEFYTLKRAERGNLVKEQLAEEKNIPQYLRSHWQKETGFAFP
SGHTMFAASWALLAVGLLWPRRRTLTIAILLVWATGVMGSRLLLGMHWPRDLVVATLISWALVAVATWLAQRICGPLTPP
AEENREIAQREQES
>SEQF1516_EDU85423.1 orotidine 5'-phosphate decarboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLTASSSSRAVTNSPVVVALDYHNRDAALAFVDKIDPRDCRLKVGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNT
AAHAVAAAADLGVWMVNVHASGGARMMTAAREALVPFGKDAPLLIAVTVLTSMEASDLADLGVTLSPADYAERLAALTQK
CGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALAAGVDYMVIGRPVTQSVDPAQTLKAINAS
LQRSA
>SEQF1516_EDU85424.1 sigma-54 dependent transcriptional regulator PspF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEYKDNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNCAALNENLLDSELFGH
EAGAFTGAQKRHPGRFERADGGTLFLDELATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGT
FRADLLDRLAFDVVQLPPLRERESDIMLMAEHFAIQMCREIKLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRH
GTSDYPLDDIIIDPFKRRPPEDAIAVSETTSLPTLPLDLREFQMQQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALL
KKHQI
>SEQF1516_EDU85425.1 methylated-DNA-[protein]-cysteine S-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRLLEEKIATPLGPLWVICDEQFRLRAVEWEEYSERMVQLLDIHYRKEGYERISATNPGGLSDKLREYFAGNLSIIDTL
PTATGGTPFQREVWKTLRTIPCGQVMHYGELAEQLGRPGAARAVGAANGSNPISIVVPCHRVIGRNGTMTGYAGGVQRKE
WLLRHEGYLLL
>SEQF1516_EDU85426.1 sensory box-containing diguanylate cyclase/cyclic diguanylate phosphodiesterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTVRESTTLYNFLGSHNPYWRLTESSDVLRFSTTETTEPERTLQLSAEQAARIREMTVITSSLMMSLTVDESDLSVHLV
GRKINKREWAGNASAWHDTPAVARDLSHGLSFAEQVVSEAHSAIVILDSRGNIQRFNRLCEDYTGLNEHDVIGQSVFKLF
MSRREAAASRRNNRVFFRSGNAYEVELWIPTRKGQRLFLFRNKFVHSGSGKNEIFLICSGTDITEERRAQERLRILANTD
SITGLPNRNAMQELIDHAINQADNNKVGVVYLDLDNFKKVNDAYGHLFGDQLLRDVSLAILSCLEHDQVLARPGGDEFLV
LASNTSQSALEAMASRILTRLRLPFRIGLIEVYTSCSVGIALSPEHGSDSAAIIRHADTAMYTAKEGGRGQFCVFTPEMN
QRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPERGLIPPLDFISYAEESGLIVPLGRWVILDVV
RQVAKWRDKGINLRVAVNISARQLADQTIFTALKQVLQELNFEYCPIDVELTESCLIENDELALSVIQQFSQLGAQVHLD
DFGTAYSSLSQLARFPIDAIKLDQVFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKEDAFLTKNGINERQGFL
FAKPMPAVAFERWYKRYLKRA
>SEQF1516_EDU85427.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQVIFNEEWMVEYGLMLRTGLGARQIEAYRQNCWVEGFHFKRVSPLGKPDSKRGIIWYNYPKINQFIKDS
>SEQF1516_EDU85428.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKHEHIESVLLALAAEKGQAWVANAITEEYLRQGGGELPLVPGKDWNNQQNIYHRWLKGETNAQREKIQKLIPAVLAI
LPRELRHRLCIFDTLERRALLAAQDALSTAIDAHDDAVQAVYRKAHFSGGGSPSDSVVVH
>SEQF1516_EDU85429.1 gamma-glutamyl-gamma-aminobutyrate hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNPVIGVVMCRNRLKGHATQTLQEKYLNAIIHAGGLPIALPHALAEPSLLEQLLPKLDGIYLPGSPSNVQPHLYGENGD
EPDADPERDLLSMALINAALERRIPIFAICRGLQELVVATGGSLHRKLCEQPELLEHREDPELPVEQQYAPSHEVQVEEG
GLLSALLPECSNFWVNSLHGQGAKVVSPRLRVEARSPDGLVEAVSVINHPFALGVQWHPEWNSSEYALSRILFEGFITAC
QHHIAEKQRL
>SEQF1516_EDU85430.1 periplasmic murein peptide-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDEPASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVP
GVATQWKSNDNRIWTFTLRDNAKWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPDQLGVTA
VDVHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESGKEWTKPGNLIGNGAYVLKERVVNEKLVVVPNTHYWDNAKTVLQ
KVTFLPINQESAATKRYLAGDIDITESFPKNMYQKLLKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTIDRR
LMTEKVLGTGEKPAWHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQKIAIAVAS
MWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLLTSTHSGNISRFNNPAYDKVLAQASTENTVK
ARNADYNAAEKILMEQAPIAPIYQYTNGRLIKPWLKGYPINNPEDVAYSRTMYIVKH
>SEQF1516_EDU85431.1 regulatory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQKTLEDVIKTVRVSVVADVCGVSQRAIYKWMDNGKLPRTEYTGETNYAEKIAHASNGLFSADAILTIGRNKTTTKKLM
GVDS
>SEQF1516_EDU85432.1 aminobenzoyl-glutamate utilization protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQEIYRFIDDAIEADRQRYTDIADQIWDHPETRFEEFWSAEHLASALESAGFTVTRNVGNIPNAFIASFGQGKPVIALLG
EYDALAGLSQQAGCAQPTSVTPGENGHGCGHNLLGTAAFAAAIAIKKWLEQYGQGGTVRFYGCPGEEGGSGKTFMVREGV
FDDVDAALTWHPEAFAGMFNTRTLANIQASWRFKGIAAHAANSPHLGRSALDAVTLMTTGTNFLNEHIIEKARVHYAITN
SGGISPNVVQAQAEVLYLIRAPEMTDVQHIYDRVAKIAEGAALMTETTVECRFDKACSSYLPNRTLENAMYQALSHFGTP
EWNSEELAFAKQIQATLTSNDRQNSLNNIAATGGENGKVFALRHRETVLANEVAPYAATDNVLAASTDVGDVSWKLPVAQ
CFSPCFAVGTPLHTWQLVSQGRTSIAHKGMLLAAKTMAATTLNLFIDSGLLQECQQEHQQVTDTQPYHCPIPKNVTPSPL
K
>SEQF1516_EDU85433.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTLLAVLFAAGFAIGWLICGLFWLRVRVSLVRAERKIKR
LENQLSPATDVAVVQHSSAAKE
>SEQF1516_EDU85434.1 aminobenzoyl-glutamate utilization protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQFVNSLAPKLSHWRRDFHHYAESGWVEFRTATLVAEELQQLGYSLALGREVVNENSRMGLPDELTLQREFERARQQGA
LAQWIAAFEGGFTGIVATLDTGRPGPVMAFRVDMDALDLSEEQDVSHRPYRDGFASCNAGMMHACGHDGHTTIGLGLAHT
LKQFESGLHGVIKLIFQPAEEGTRGARAMVDAGVVDDVDYFTAVHIGTGVPAGTVVCGSDNFMATTKFDAHFTGTAAHAG
AKPEDGYNALLAAAQATLALHAIAPHSEGASRVNVGVMQAGSGRNVVPASALLKVETRGASDVINQYVFDRAQQAIQGAA
TMYGVGVETRLMGAATASSPSPQWVAWLQSQAAQVAGVNQAIERVEAPAGSEDATLMMARVQQHQGQASYVVFGTQLAAG
HHNEKFDFDEQVLAIAVETLARTALNFPWTRGI
>SEQF1516_EDU85435.1 phage shock protein PspD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTRWQQAGQKVKPGFKLAGKLVLLTALRYGPAGVAGWAIKSVARRPLKMLLAVALEPLLSRAANKLAQRYKR
>SEQF1516_EDU85436.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU85437.1 gp45 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLVKQLVSQLKKAKPGCKLPDKVMDYLERSGLISVEDVSR
>SEQF1516_EDU85438.1 phage shock protein E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKKGLLALALVFSLPVFAAEHWIDVRVPEQYQQEHVQGAINIPLKEVKERIATVVPDKNDTVKVYCNAGRQSGQAKEIL
SEMGYTHVENAGGLKDIAMPKVKG
>SEQF1516_EDU85439.1 ATP-independent RNA helicase DbpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVRVQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPT
RELADHVASELRPLARFLPNTKILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLD
MGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQQFYETSSKGKIPLLQRLLSLHQ
PSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLEQRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAW
DPEVHVHRIGRTARAGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIVTLEAEMATLCIDGGKKAKMRPGDV
LGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKTCRVRLLK
>SEQF1516_EDU85440.1 hypothetical protein ECH7EC4501_1742 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFTVTDGQPQNGHGLTLSYLIIFLIKIFQVGGALHRQAELFL
>SEQF1516_EDU85441.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLTKKERAWLNELQEVLDRCPSPKKIGFYTIGDKSIYLYDLRRMDEIMEALDNRSSMDWCVAVHDMNAGFDEKILFPS
SVESTAG
>SEQF1516_EDU85442.1 peptide transport system, ATP-binding protein SapF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIETLLEVRNLSKTFRYRTGWFRRQTVEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHF
GDYSFRSQRIRMIFQDPSTSLNPRQRISQILDFPLRLNTNLEPEQRRKQIIETMRMVGLLPDHVSYYPHMLAPGQKQRLG
LARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHISDQVLVMHQGEVVERGSTADVLA
SPLHELTKRLIAGHFGEALTADAWRKDR
>SEQF1516_EDU85443.1 putative bacteriophage protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPEMAGIRSTLIKEKNMITNYEATVVTTDDIVHEVNLEGKRIGYVIKTENKETPFTVVDIDGPSGNVKTLDEGVKKMCLV
HIGKNLPTEKKAEFLATLIAMKLKGEI
>SEQF1516_EDU85444.1 hypothetical protein ECH7EC4501_1808 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNPLKHAAVRVIVSRMRRERFIRTTILTDRLQLNNYSLPH
>SEQF1516_EDU85445.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKIDLGNNESLVCGVFPNQDGTFTAMTYTKSKTFKTETGARRWLEKHTVS
>SEQF1516_EDU85446.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVHYEVVQYLMDCCGITYNQAVQALRSNDWDLWQAEVAIRSNKM
>SEQF1516_EDU85447.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYKITATIEKEGGTPTNWTRYSKSKLTKSECEKMLSGKKEAGVSREQKVKLINFNCEKLQSS
>SEQF1516_EDU85448.1 sensory box-containing diguanylate cyclase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTWLFCDRIATKIDKNNGISMITHNFNTLDLLTSPVWIVSPFEEQLIYANSAARLLMQDLTFSQLRTGPYSVSSQKELPK
YLSDLQNQHDIIEILTVQRKEEETALSCRLVLRELTETEPVIIFEGIEAPATLGLKASRSANYQRKKQGFYARFFLTNSA
PMLLIDPSRDGQIVDANLAALNFYGYNHETMCQKHTWEINMLGRRVMPIMHEISHLPGGHKPLNFIHKLADGSTRHVQTY
AGPIEIYGDKLMLCIVHDITEQKRLEEQLEHAAHHDAMTGLLNRRQFYHITEPGQMQHLAIAQDYSLLLIDTDRFKHIND
LYGHSKGDEVLCALARTLESCARKGDLVFRWGGEEFVLLLPRTPLDTALSLAETIRVSVAKVSISGLPRFTVSIGVAHHE
GNESIDELFKRVDDALYRAKNDGRNRVLAA
>SEQF1516_EDU85449.1 transcriptional regulator PuuR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDEGLAPGKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDKVSPAISTLQKLLKVYGLSLSEFFSEPEKPDEPQVVI
NQDDLIEMGSQGVSMKLVHNGNPNRTLAMIFETYQPGTTTGERIKHQGEEIGTVLEGEIILTINGQDYHLVAGQSYAINT
GIPHSFSNTSAGICRIISAHTPTTF
>SEQF1516_EDU85450.1 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNFHHLAYWQDKALSLAIENRLFINGEYTAAAENETFETVDPVTQAPLANIARGKSVDIDRAVSAARGVFERGDWSLSSP
AKRKAVLNKLADLIEANAEELALLETLDTGKPIRHSLRDDIPGAARAIRWYAEAIDKVYGEVATTSSHELAMIVREPVGV
IAAIVPWNFPLLLTCWKLGPALAAGNSVVLKPSEKSPLSAIRLAGLAKEAGLPDGVLNVVTGFGHEAGQALSRHNDIDAI
AFTGSTRTGKQLLKDAGDSNMKRVWLEAGGKSANIVFADCPDLQQAASATAAGIFYNQGQVCIAGTRLLLEESIADEFLA
LLKQQAQNWQPGHPLDPATTMGTLIDCAHADSVHSFIQEGESKGQLLLDGRNAGLAVAIGPTIIVDVDPNASLSREEIFG
PVLVVTRFTSEEQALQLANDSQYGLGAAVWTRDLSRAHRMSRRLKAGSVFVNNYNDGDMTVPFGGYKQSGNGRDKSLHAL
EKFTELKTIWISLEA
>SEQF1516_EDU85451.1 putative sugar ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRLFSGRSDMPFALLLLAPSLLLLGGLVAWPMVSNIEISFLRLPLNPNIESTFVGVSNYVRILSDPGFWHSLWMTVWYT
ALVVAGSTVLGLAVAMFFNREFRLRKTARSLVILSYVTPSISLVFAWKYMFNNGYGIVNYLGVDLLHLYEQAPLWFDNPG
SSFVLVVIFAIWRYFPYAFISFLAILQTIDKSLYEAAEMDGANAWQRFRIVTLPAIMPVLATVVTLRTIWMFYMFADVYL
LTTKVDILGVYLYKTAFAFNDLGKAAAISVVLFIIIFAVILLTRKRVNLNGNK
>SEQF1516_EDU85452.1 aminobenzoyl-glutamate transport protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSMSSIPSSSQSGKLYGWVERIGNKVPHPFLLFIYLIIVLMVTTAILSAFGVSAKNPTDGTPVVVKNLLSVEGLHWFLPN
VIKNFSGFAPLGAILALVLGAGLAERVGLLPALMVKMASHVNARYASYMVLFIAFFSHISSDAALVIMPPMGALIFLAVG
RHPVAGLLAAIAGVGCGFTANLLIVTTDVLLSGISTEAAAAFNPQMHVSVIDNWYFMASSVVVLTIVGGLITDKIIEPRL
GQWQGNSDEKLQTLTEMNRPGNPGD
>SEQF1516_EDU85453.1 transcriptional regulator, DeoR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKLSYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFA
ASLVQPGETIFIENGSSNALLARTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVERFNRVITDSKIRASDLMHLEHS
KLTVHVVDI
>SEQF1516_EDU85454.1 phage shock protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVRSTSARALAEKKQLTRRIEQASAREVEWQEKAELALL
KEREDLARAALIEKQKLTDLIKSLEHEVTLVDDTLARMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGK
LDEAMARFESFERRIDQMEAEAESHSFGKQKSLDDQFAELKADDAISEQLAQLKAKMKQDNQ
>SEQF1516_EDU85455.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNHDIPLKYFDIADEYATECAEPVADAERTPLAHYFQLLLTRLMNNEEISEEAQHEMAAEAGINPVRIDEIAEFLNQWGN
E
>SEQF1516_EDU85456.1 universal stress protein E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDFSYEMTTLLSPDERTAMRQGVISQRTAWIHEQAKYYL
NAGVPIEIKVVWHNRPFEAIIQEVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAV
NLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYNDAIRGQHLLAMKALRQKFGINE
NMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGISAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD
>SEQF1516_EDU85457.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVMTKKIKCAYHLCKKDVEESKAIERMLHFMHGILSKDEPRKYCSEACAEKDQMAHEL
>SEQF1516_EDU85458.1 glycosyl hydrolase, family 65 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRPVTLSEPHFSQHTLNKYASLMAQGNGYLGLRASHEEDYTRQTRGMYLAGLYHRAGKGEINELVNLPDILGMEIAING
EVFSLSHEAWQRELDFASGELRRNVVWRTSNGAGYTIASRRFVSADQLPLIALEITITPLDADASVLISTGIDATQTNHG
RQHLDETQVRVFGQHLMQGIYTTQDGRSDVAISCCCKVSGDVQQCYTAKERRLLQHTSAQLHAGETVTLQKLVWIDWRDD
RQAVLDEWGSASLRQLEICAQQSYDQLLAASTENWRQWWQKRRITVNGGDAHDQQALDYALYHLRIMTPAHDERSSIAAK
GLTGEGYKGHVFWDTEVFLLPFHLFSDPTVARSLLRYRWHNLPGAQEKARRSGWQGALFPWESARSGEEETPEFAAINIR
TGLRQKVASAQAEHHLVADIAWAVIQYWQTTGDESFIAHEGMALLLETAKFWISRAVRVNDRLEIHDVIGPDEYTEHVNN
NAFTSYMARYNVQQALNIARQFGCSDDAFIHRAEMFLKELWMPETQPDGVLPQDDSFMAKPAINLAKYKAAAGKQTILLD
YSRAEVNEMQILKQADVVMLNYMLPEQFSAVSCLANLQFYEPRTIHDSSLSKAIHGIVAARCGLLTQSYQFWREGTEIDL
GADPHSCDDGIHAAATGAIWLGAIQGFAGVSVRDGELHLNPALPEQWQQLSFPLFWQGCELQVTLDAQRIAIRTSAPVSL
RLNGQLISVAEESVFCLGDFILPFNGTATTHQEDE
>SEQF1516_EDU85459.1 protein YdaO [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQENQQITKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMVCLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQK
QPGFPEHVLPEYLEKLGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFL
NMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPNLQRQVIADMLRDWDKRYPGRIE
TMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGDLAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK
>SEQF1516_EDU85460.1 osmotically inducible lipoprotein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFVTSKKMTAAVLAITLAMSLSACSNWSKRDRNTAIGAGAGALGGAVLTDGSTLGTLGGAAVGGVIGHQVGK
>SEQF1516_EDU85461.1 amino acid permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAINSPLNIAAQPGKTRLRKSLKLWQVVMMGLAYLTPMTVFDTFGIVSGISDGHVPASYLLALAGVLFTAISYGKLVRQF
PEAGSAYTYAQKSINPHVGFMVGWSSLLDYLFLPMINVLLAKIYLSALFPEVPPWVWVVTFVAILTAANLKSVNLVANFN
TLFVLVQISIMVVFIFLVVQGLHKGEGVGTVWSLQPFISENAHLIPIITGATIVCFSFLGFDAVTTLSEETPDAARVIPK
AIFLTAVYGGVIFIAASFFMQLFFPDISRFKDPDAALPEIALYVGGKLFQSIFLCTTFVNTLASGLASHASVSRLLYVMG
RDNVFPERVFGYVHPKWRTPALNVIMVGIVAMSALFFDLVTATALINFGALVAFTFVNLSVFNHFWRRKGMNKSWKDHFH
YLLMPLVGALTVGVLWVNLESTSLTLGLVWASLGGAYLWYLIRRYRKVPLYEGDRTPVSET
>SEQF1516_EDU85462.1 monomeric porin OmpG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLLPCTALVMCAGMACAQAEEKNDWHFNIGAMYEIENVEGYGEDMDGLAEPSVYFNAANGPWRISLAYYQEGPVDYSA
GKRGTWFDRPELEVHYQFLESDDFSFGLTGGFRNYGYHYVDEPGKDTANMQRWKIAPDWDVKLTDDLRFNGWLSMYKFAN
DLNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDDSRNNGEFSTQEIRAYLPLTLGNHSVTPYTRIGLDRWSN
WDWQDDIEREGHDFNRVGLFYGYDFQNGLSISLEYAFEWQDHDEGDSDKFHYAGVGVNYSF
>SEQF1516_EDU85463.1 DNA replication protein DnaC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIATGGVLERIRRLAPPHVTAPFRTVAEWREWQLAEGQKRCEEINRQNRQLRVEKILNRSGIQPLHRKCSFANYQVQN
DGQRYALSQAKSIADELVTGCTNFAFSGKPGTGKNHLAAAIGNRLLKDGQTVIVVTVADVMSALHASYDDGQSGEKFLRE
LCEVDLLVLDEIGIQRETKNEQVVLHQIVDRRTASMRSVGMLTNLNYEAMKTLLGERIMDRMTMNGGRWVNFNWESWRPN
VGQPGIEK
>SEQF1516_EDU85464.1 hypothetical protein ECH7EC4501_1794 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGAYAPFFSVTPYLHPYRLFASAHKYAFSLVKNDFLRD
>SEQF1516_EDU85465.1 transcriptional regulator, LacI family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSPTIYDIARVAGVSKSTVSRVLNKQTNISPEAREKVLRAIEELQYQPNKLARALTSSGFDAIMVISTRSTKTTAGNPFF
SEVLHAITAKAEEEGFDVILQTSHTPAEDLQKCESKIKQKMIKGIIMLSSPADESFFAQLDKYDIPVVVIGKVEGQYAHV
YSVDTDNFGDSIALTDALIESGHQNIACLHAPLDVHVSVDRVNGYKQSLEDHNIAVRDEWIVDGGYTHETALQAARQLLS
QSPLPEAVFATDSLKLMSIYRAAAEKNIAIPQQLAVVGYSNETLSFILTPAPGGIDVPTQELGRQSCELLFRLIAGKPSP
QNITVATHMTLK
>SEQF1516_EDU85466.1 exodeoxyribonuclease 8 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTKPLFLLRKAKKSSGEPDVVLWASNDFESTCATLDYLIVKSGKKLSSYFKAVATNFPVVNDLPAEGEIDFTWSERYQL
SKDSMTWELKPGAAPDNAHYQGNTNVNGEDMTEIEENMLLPISGQELPIRWLAQHGSEKPVTHVSRDGLQALHIARAEEL
PAVTALAVSHKTSLLDPLEIRELHKLVRDTDKVFPNPGNSNLGLITAFFEAYLNADYTDRGLLTKEWMKGNRVSHITRTA
SGANAGGGNLTDRGEGFVHDLTSLARDVATGVLARSMDLDIYNLHPAHAKRIEEIIAENKPPFSVFRDKFITMPGGLDYS
RAIVVASVKEAPIGIEVIPAHVTEYLNKVLTETDHANPDPEIVDIACGRSSAPMPQRVTEEGKQDDEEKPQPSGTTAVEQ
GEAETMEPDATEHHQDTQPLDAQSQVNSVDAKYQELRAELHEARKNIPSKNPVDADKLLAASRGEFVDGISDPNDPKWVK
GIQTRDCVYQNQPETEKTSPDMNQPEPVVQQEPEIACNACGQTGGDNCPDCGAVMGDATYQETFDEESQVEAKENDPEEM
EGAEHPHNENAGSDPHRDCSDETGEVADPVIVEDIEPGIYYGISNENYHAGPGVSKSQLDDIADTPALYLWRKNAPVDTT
KTKTLDLGTAFHCRVLEPEEFSNRFIVAPEFNRRTNSGKEEEKAFLRECASTGKTVITAEEGRKIELMYQSVMALPLGQW
LVESAGHAESSIYWEDPETAILCRCRPDKIIPEFHWIMDVKTTADIQRFKTAYYDYRYHVQDAFYSDGYEAQFGVQPTFV
FLVASTTIECGRYPVEIFMMGEEAKLAGQLEYHRNLRTLADCLNTDEWPAIKTLSLPRWAKEYAND
>SEQF1516_EDU85467.1 beta-phosphoglucomutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESLKGISRDESLRRILQHGGKEGDFNPQERTQLAYRKNL
LYVHSLRELTVNAVLPGIRNLLAELRAQQIPVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
GVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTDSLTWPRLSAFWQNV
>SEQF1516_EDU85468.1 hypothetical protein ECH7EC4501_1773 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQILRIIKSFSSTLCHRSCITFLPEVVCIFIDVQILELS
>SEQF1516_EDU85469.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIAHHFGTDEIPRQCVTPGDYVLHEGRTYIASANNIKKRKLYIRNLTTKTCITDRMIKVFLGRDGLPVKAESW
>SEQF1516_EDU85470.1 putative sugar ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATNKRTLSRIGFYRGLALFLIITLFPFFVMLMTSFKSAKEAISLHPTLLPQQWTLEHYVDIFNPVIFPFVDYFRNSMVV
SVVSSVVAVFLGILGAYALSRLRFKGRMTINASFYTVYMFSGILLVVPLFKIITALGIYDTEMALIITMVTQTLPTAVFM
LKSYFDTIPDEIEEAAMMDGLNRLQIIFRITVPLAMSGLISVFVYCFMVAWNDYLFASIFLSSASNFTLPVGLNALFSTP
DYIWGRMMAASLVTALPVVIMYALSERFIKSGLTAGGVKG
>SEQF1516_EDU85471.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQRHITGKSHWYHETQSSTTEYDVLPLVPEAAKVSDPFLLDVILEKETLAPFLSWLDPARVLAVELFPDQLTVTRSQTF
TAYERLSTALTVAQVCGVQRLCNYYSARLTPLPGPDSTRESNHRLAQITQYARQLASSPSIIDNRSRQHLNDVGLTAWDC
VIINQIIGFIGFQARTIATFQAYLGHPVRWLPGLEIQNYADASLFADESLRWRSSYEVEKLPEEHTKSSTAELCQLAEIL
SLHPISLSLLERLLNSTRVNTQPDNQLAALLCARINGSPACFAACMDSSNEYKKISPLLRKGENEINQWADRHSVERATV
QAIQWLTRAPDRFSAAQFSPLLEHEKSSTQIINLLVWSGLCGWINRLKIALGETY
>SEQF1516_EDU85472.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METVFDALKAMGKATSVELATRLDISREEVLNELWELKKAGFVDKSVYTWRVADNNVQQEQPAPAELPEETTMATVAKIS
ECDLTATIEQRGPQTADELATLFGTTSRKVASTLAMAISKGRLIRVNQNGKFRYCIPGDNLPAEPKAASVAETDGKAFPQ
PTGVALPVQEAATQEDIKTETVADIVQSLPSFTETRADDLVLPSLHMANRELRRAKNHVQKWERVCAALRELNKHRDIVR
QIFDSSSRIVSEK
>SEQF1516_EDU85473.1 NmrA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNVLILGAGGQIARHVINQLADKQTIKQTLFARQPAKIHKPYPTNSQIIMGDVLNHAALKQAMQGQDIVYANLTGEDLD
IQANSVIAAMKACDVKRLIFVLSLGIYDEVPGKFGEWNNAVIGEPLKPFRRAADAIEASGLEYTILRPAWLTDEDIIDYE
LTSRNEPFKGTIVSPKSVAALITDIIDKPEKHIGENIGINQPGTDGDKPFFM
>SEQF1516_EDU85474.1 hypothetical protein ECH7EC4501_1829 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMGTGSGAKQVNGEHSTRGNKKLTVVISPLAGFLCAAVAGAQWDINN
>SEQF1516_EDU85475.1 oxidoreductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSAMTSSPLRVAIIGAGQVADKVHASYYCTRNDLELVAVCDSRLSQAQALAEKYGNASVWDDPQAMLLAVKPDVVSVCS
PNRFHYEHTLMALEAGCHVMCEKPPAMTPEQAREMCDTARKQGKVLAYDFHHRFALDTQQLREQVTNGVLGEIYVTTARA
LRRCGVPGWGVFTNKELQGGGPLIDIGIHMLDAAMYVLGYPAVKSVNAHSFQKIGTQKSCGQFGEWDPATYSVEDSLFGT
IEFHNGGILWLETSFALNIREQSIMNVSFCGDKAGATLFPAHIYTDNNGELMTLMQREMADDNRHLGSMEAFINHVQGKP
VMIADAEQGYIIQQLVAALYQSAETGTRVEL
>SEQF1516_EDU85476.1 zinc transport protein ZntB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLHLNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVS
RLGEGTLITLRCINGSTDERPDQLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSE
FIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPWMSDDQRRRMQDIADRLGRGLDE
IDACIARTGVMADEIAQVMQENLARRTYTMSLMAMVFLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALW
LHRSKWL
>SEQF1516_EDU85477.1 superinfection exclusion protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYTIIIFGLTLWLIPKEFTVAFNAYTEIPWLFQIIVFAFSFVVAISFSRLRAHIQKHYSLLPEQRVLLRLSEKEIAVFKD
FLKTGNLIITSPCRNPVMKKLERKGIIQHQSDSANCSYYLVTEKYSHFMKLFWNSRSRRFNR
>SEQF1516_EDU85478.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRLKNELNALVNRGVDRHLRLAVTGLSRSGKTAFITAMVNQLLNIHAGARLPLLSAVREERLLGVKRIPQRDFGIPRFT
YDEGLAQLYGDPPAWPTPTRGVSEIRLALRYKSNDSLLRHFKDTSTLYLEIVDYPGEWLLDLPMLAQDYLSWSRQMTGLL
NGQRGEWSAKWRMMCEGLDPLAPADENRLADIAAAWTDYLHHCKQQGLHFIQPGRFVLPGDMAGAPALQFFPWPDVDAWG
ESKLAQADKHTNAGMLRERFNYYCEKVVKGFYKNHFLRFDRQIVLVDCLQPLNSGPQAFNDMRLALTQLMQSFHYGQRTL
FRRLFSPVIDKLLFAATKADHVTIDQHANMVSLLQQLIQDAWQNAAFEGISMDCLGLASVQATTSGIIDVNGEKIPALRG
NRLSDGAPLTVYPGEVPARLPGQAFWDKQGFQFEAFRPQVMDVDKPLPHIRLDAALEFLIGDKLR
>SEQF1516_EDU85479.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIMAKLKSAKGKKFLFGLLAVFIIAASVVTRATIGGVIEQYNIPLSEWTTSMYVIQSSMIFVYSLVFTVLLAIPLGIYFL
GGEEQ
>SEQF1516_EDU85480.1 transporter, small conductance mechanosensitive ion channel family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHAVQFLIYTIIISAVGSIINYVIENYKLKFITPGVIDF
ICTSLIAVILTIKLFLLINQFEKQQIKKGRDITSARIMSRIIKITIIVVLVLLYGEHFGMSLSGLLTFGGIGGLAVGMAG
KDILSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITKITTFDNRPLYVPNSLFSSISVENPGRMTNRRITTT
IGLRYEDAAKVGVIVEAVREMLKNHPAIDQRQTLLVYFNQFADSSLNIMVYCFTKTTVWAEWLAAQQDVYLKIIDIVQSH
GADFAFPSQTLYMDNITPPEQGR
>SEQF1516_EDU85481.1 thiol peroxidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFAGKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVV
LCISADLPFAQSRFCGAEGLNNVITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYE
AALAVLKA
>SEQF1516_EDU85482.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEERLGLRLLTRTTRSVVPTEAGEHLLSVLGPMLHDIDS
ALASLSDLQNRPSGTIRITTVEHAAKTILLPAMRTFLKSHPEIDIQLIIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRI
GPDIPMAIVGSPDYFSRRSVPTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVRMEGQLLLNTIDLIIDAAIDGHG
LAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYYPHRRHAGSAFSLFIDRLKYKGAV
>SEQF1516_EDU85483.1 Smr domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLDDKSLFLDAMEDVQPLKRATDVHWHPTRNQRAPQRIDTLQLDNFLTTGFLDIIPLSQPLEFRREGLQHGVLDKLRSG
KYPQQASLNLLRQPVEECRKMMFSFIQQAMADGLRNVLIIHGKGRDDKSHANIVRSYVARWLTEFDDVQAYCTALPHHGG
SGACYVALRKTAQAKQENWERHAKRSR
>SEQF1516_EDU85484.1 peptide ABC transporter, permease protein SapC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCMFGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGT
DDLGRDVLSRLLSGAAPTVGGAFVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSH
AMFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVTEITRALSMAILDIAALGFLDLG
AQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMISVLLVNLLGDGVRRAIIAGVE
>SEQF1516_EDU85485.1 putative transcriptional regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVHEDKARKEFASRLALACENAGYEQHGRQAEIARRMKLTPKAVSKWFNGETIPRREKLRELATLIGTTPTYLLGEDTEE
SGQIRFYQELNPRQKIIIDLLDELPDSETDELLKTLEEKKQKYNAIYEELARKKKQKAS
>SEQF1516_EDU85486.1 sugar ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQLSLQHIQKIYDNQVHVVKDFNLEIADKEFIVFVGPSGCGKSTTLRMIAGLEEISGGDLLIDGKRMNDVPAKARNIAM
VFQNYALYPHMTVYDNMAFGLKMQKIAKEVIDERVNWAAQILGLREYLKRKPGALSGGQRQRVALGRAIVREAGVFLMDE
PLSNLDAKLRVQMRAEISKLHQKLNTTMIYVTHDQTEAMTMATRIVIMKDGIVQQVGAPKTVYNQPANMFVAGFIGSPAM
NFIRGTIDGDKFVTETLKLTIPEEKLAVLKTQESLHKPIVMGMRPEDIHPDAQEENNISAKISVVELTGAEFMLYTTVGG
HELVVRAGALNDYHAGENITIHFDMTKCHFFDAETEIAIR
>SEQF1516_EDU85487.1 peptide ABC transporter, permease protein SapB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIFTLRRILLLIVTLFLLTFVGFSLSYFTPHAPLQGASLWNAWVFWFNGLIHWDFGVSSINGQPIAEQLKEVFPATMEL
CILAFGFALIVGIPVGMIAGITRHKWQDNLINAIALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKPITGFA
LIDAWLSDSPWRDEMIMSAIRHMILPVITLSVAPTTEVIRLMRISTIEVYDQNYVKAAATRGLSRFTILRRHVLHNALPP
VIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEWYAL
R
>SEQF1516_EDU85488.1 peptide ABC transporter, periplasmic peptide-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVIAGLVSGQAIAAPESPPHADIRDSGFVYCVSGQVNTFNPSKASSGLIVDTLAAQFYDRLLDVDPYTYRLMPELAESWE
VLDNGATYRFHLRRDVPFQKTAWFTPTRKMNADDVVFTFQRIFDRNNPWHNVNGSNFPYFDSLQFADNVKSVRKLDNHTV
EFRLAQPDASFLWHLATHYASVMSAEYARKLEKEDRQEQLDRQPVGTGPYQLSEYRAGQFIRLQRHDDFWRGKPLMPQVV
VDLGSGGTGRLSKLLTGECDVLAWPAASQLSILRDDPRLRLTLRPGMNVAYLAFNTAKPPLNNPAVRHALALAINNQRLM
QSIYYGTAETAASILPRASWAYDNEAKITEYNPAKSREQLKLLGLENLTLKLWVPTRSQAWNPSPLKTAELIQADMAQVG
VKVVIVPVEGRFQEARLMDMSHDLTLSGWATDSNDPDSFFRPLLSCAAIHSQTNLAHWCDPKFDSVLRKTLSSQQLAARI
EAYDEAQSILAQELPILPLASSLRLQAYRYDIKGLVLSPFGNASFAGVYREKQDEVKKP
>SEQF1516_EDU85489.1 multidrug efflux outer membrane protein EefC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRRSLIFLVLLSAGCVSLDPHYSTPESPIPATLPGAQGQGKAISHDWQQVIHDPRLQQVVTIALNSNRDVQKAIADIDS
ARALYGQTNASLFPTVNAALSSTRSRSLANGTETTAEADGTVSSFTLDLFGRNQSLSRAARETWLASEFTAQNTRLTLIA
EISTAWLTLAADNSNLALAKETMTSAENSLKIIQRQQQVGTAAATDVSEAMSVYQQARASVASYQTQVMQDKNALNLLAG
TTLEENLLPGTLESLPEQMISLVPAGVSSDVLLRRPDIQEAEHNLKSANADIGAARANFFPTISLTASAGVGSDALSSLF
SHGMQIWSFTPSVTLPLFTGGSNLAQLRYAEAQKRGLIATYEKTVQRAFKDVANALARRTTLEEQLDAQRQYVKAEQQTV
DVGLRRYQTGVGDYLTVLTAQRSLWSAQQELLALQLTDFTNRITLWQSLGGGMSSLK
>SEQF1516_EDU85490.1 aminobenzoyl-glutamate transport protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVIPENGILRDPINHTVMPSPFIKGIVPLIILFFFVVSLAYGIATRTIRRQADLPHLMIEPMKEMAGFIVMVFPLAQFVA
MFNWSNMGKFIAVGLTDILESSGLSGIPAFVGLALLSSFLCMFIASGSAIWSILAPIFVPMFMLLGFHPAFAQILFRIAD
SSVLPLAPVSPFVPLFLGFLQRYKPDAKLGTYYSLVLPYPLIFLVVWLLMLLAWYLVGLPIGPGIYPRLS
>SEQF1516_EDU85491.1 gamma-glutamylputrescine oxidoreductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEHTSSYYAASANKYAPFDTLNESISCDVCVVGGGYTGLSSALHLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYSRD
IDVIEKSYGMDTARMLGSMMFEGGEIIRERIKRYQIDCDYRPGGLFVAMNDKQLATLEEQKENWERYGNKQLEMLDANAI
RREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLNGGRVYELSAVTQIQHTTPAVVRTATGQVTAKYVIVAGNAYLGD
KVEPELAKRSMPCGTQVITTERLSDDLARSLIPKNYGVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVERLVVPKL
LKTFPQLKGVKIDYRWTGNFLLTLSRMPQFGRLDTNIYYMQGYSGHGVTCTHLAGRLIAELLRGDAERFDAFANLPHYPF
PGGRTLRVPFTAMGAAYYSLRDRLGV
>SEQF1516_EDU85492.1 tetratricopeptide repeat protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVNFLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFR
SRGEVDRAIRIHQTLMESASLTYEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKA
IDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSIMMGRVFMAKGEYAKAVESLQRV
ISQDRELVSETLEMLQTCYQQLGKTAEWAEFLQRAVEENTGADAELMLADIIEARDGSEAAQVYITRQLQRHPTMRVFHK
LMDYHLNEAEEGRAKESLMVLRDMVGEKVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGL
>SEQF1516_EDU85493.1 peptide ABC transporter, ATP-binding protein SapD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSA
RERRKLVGHNVSMIFQEPQSCLDPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHDLQMLSQWADKINVLYCGQTVET
APSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLNTLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYA
CHFPLNMEKE
>SEQF1516_EDU85494.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLILAGTHGDENSSVVTLSCALRTLTPSLRRHHVVLCVN
PDGCQLGLRANANGVDLNRNFPAANWKEGETVYRWNSAAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPL
ACIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDEASEKYLFAMANLLRWHPKDAIR
PS
>SEQF1516_EDU85495.1 multidrug efflux transport protein EefA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYIATSVVAMLLLSGCDNTQSNNSSPSETEVGVVTVKSQPVSVVSELTGRTSAALSAEVRPQVGGIIQKRLFKEGDLVK
AGQPLYQIDAASYQAAWNEARAALQQAQALVKADCQKAQRYARLVKENGVSQQDADDAQSTCAQDKASVAAKKAALETAR
INLDWTTVTAPISGRIGISSVTPGALVTASQDTALTTIRGLDTMYVDLTRSSVDLLRLRKQSLATNSDTMSVSLILEDGT
TYSEKGRLELTEVAVDESTGSVTLRAIFPNPQQQLLPGMFVRARVDEGVMEDAILAPQQGVTRDAKGNATALVVNKDNKV
EQRTLETGETYGDKWLVLNGLHSGDRLIVEGSAKVTSGQTVKAVEVQANGGNA
>SEQF1516_EDU85496.1 exoribonuclease II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSYFIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVE
PFLTRFVGKVQGKNDRLAIVPDHPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP
WWVTLARHNLEKEAPDGVATEMLDEGLVRKDLTALDFVTIDSASTEDMDDALFAKALPDDKLQLIVAIADPTAWIAEGSK
LDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRANEVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWL
ENTGDWQPESEAIAEQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEAMIAANICA
ARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFCKLRRELDAQPTGFLDSRIRRFQSFAEISTE
PGPHFGLGLEAYATWTSPIRKYGDMINHRLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGT
DTRFAAEIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVIDVTIAEVRMETRSIIA
RPVA
>SEQF1516_EDU85497.1 enoyl-(acyl-carrier-protein) reductase (NADH) [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGK
VWPKFDGFVHSIGFAPGDQLDGDYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG
LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRRTVTIEDVGNSAAFLCSDLSAGI
SGEVVHVDGGFSIAAMNELELK
>SEQF1516_EDU85498.1 multidrug efflux transport protein EefD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARVSLSWALILGLLAGIGPMCTDLYLPALPEMSEQLAATTTITQLTLTASLIGLGVGQLLFGPLSDKIGRKRPLILSLL
LFIVSSILCATTNNIYWLVVWRFIQGIAGAGGSVLSRSIARDKYQGVTLTQFFALLMTVNGLAPVLSPVLGGYIVSTFDW
RTLFWVMAEISTVLLLGCVLFINETLPENKRGSSLLLTGRSVVQNRRFMRFCLIQSFMLAGLFAYIGSSSFVLQKEFGFS
PMQFSLVFGLNGIGLIIASWIFSRLARRINAMTLLRGGLIAAILCALLTVLCAWTQLPIPALVALFFTIAFCSGIGTVGG
AEAMSAVGTQESGTASALMGMSMFVFGGIAAPLSGFGGETLLKMSLAITVCYTLAFLVALTRIDNQK
>SEQF1516_EDU85499.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEFDAQRVAERIDIVLDILVADDYHSAIHNLEILKAELLRQVAESTPDIPKAPWEI
>SEQF1516_EDU85500.1 phage shock protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSALFLAIPLTIFVLFVLPIWLWLHYSNRSGRSELSQSEQQRLAQLADEAKRMRERIQALESILDAEHPNWRDR
>SEQF1516_EDU85501.1 transcriptional regulatory protein TyrR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFAELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHL
ALSALLEALPEPVLSVDMKSKVDMANPASCQLFGQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLME
ITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVEQAQKLAMLSAPLLITGDTGTGK
DLFAYACHQASPRASKPYLALNCASIPEDAVESELFGHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTF
RRVGEDHEVHVDVRVICATQKNLVELVQKGMFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQGVPRPKLA
ADLNTVLTRYAWPGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATVAVGEDAMEGSLDEITSRFERSVLTQLYRNY
PSTRKLAKRLGVSHTAIANKLREYGLSQKKNEE
>SEQF1516_EDU85502.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEPLKPRIDFDGPLEVEQNPKFRAQQTFDENQAQNFAPATLDEAQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGA
SVVGQGVQWTMNAWQTQDWVALGGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQ
QAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMIAVSPLALVDMAFIAWRNLRLIN
RIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVREVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLP
WIDDDKPRLGDFRRQLIGQVKETLQKGKTPSEK
>SEQF1516_EDU85503.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNTQKAINAEKYNEWARKFSEQIFKITGDENAAKNELEPWTPEGADPNYCWREVDPVDAANEAMSYHND
>SEQF1516_EDU85504.1 hypothetical protein ECH7EC4501_1750 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVLLYGCIVVNGCNKSNFSGCLYTKTPQSLSEVNKLSTHSGQYLSCR
>SEQF1516_EDU85505.1 fumarate and nitrate reduction regulatory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDNIIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYT
ITEQGDEQITGFHLAGDLVGFDAIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILL
LSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRFQKSGMLAVKGKYITIENNDALA
QLAGHTRNVA
>SEQF1516_EDU85506.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMNNKVSFTNSNNPTISLSAVIYFPPKFDETRQYPAIVVSHPGGGVKEQTAGTYAEKLAEKGFVTIAYDASYQGESGGEP
RQLENPYIRTEDVSAVIDYLTTLSYVDNTRIGAMGICAGAGYTANAAIQDRRIKAIGTVSAVNIGSMFRNGWENNVKSID
ALPYVEAGSNARTSDISSGEYAIMPLAPMKESDAPNEELRQAWEYYHTPRAQYPTAPGYATLRSLNQIITYDAYHMAEVY
LTQPTQIVAGSQAGSKWMSDDLYDRASSQDKRYHIVEGANHMDLYDGKAYVAEAISVLAPFFEETL
>SEQF1516_EDU85507.1 oxidoreductase, zinc-binding dehydrogenase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVDFRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQ
LGNMVVGDIIECGSDVTDYAVGDSVCGYGPLSETIIINAVNNYKLRKMPEGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEIKTLTGKQGADVIIETSGYADAL
QSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNNAKIVFSRACSEPNPDYPRWSRKRIEETCWKLLMNGYLNCEDLID
PVVTFANSPESYMQYVDQHPEQSIKMGVTF
>SEQF1516_EDU85508.1 transcriptional regulator EefR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSKLEIRHKQRQDEIINAARRCFRRCGFHAASMSQIASEAQLSVGQIYRYFANKDAIIEEMVRRIIDFRIAQMDIDART
DHFPEVLALRKSLNEDDDALMLEVAAEATRNPRVMAMLEEADARMFANGCAHMKRMHPHLSEEHIRCCVEVFATMMEGTV
YRRLTPQKSDPQHLQEIYQDIVSMLINK
>SEQF1516_EDU85509.1 putative translation initation factor SUI1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMSDSNSRLVYSTETGRIDEPKAAPVRSKGDGVVRIQRQTSGRKGKGVCLITGIDLDDAELTKLAAELKKKCGCGGAVKD
GVIEIQGDKRDLLKSLLEAKGMKVKLAGG
>SEQF1516_EDU85510.1 phage shock protein C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGINLNKKLWRIPQQGMVRGVCAGIANYFDVPVKLVRILVVLSIFFGLALFTLVAYIILSFALDPMPDNMAFGEQLPSS
SELLDEVDRELAASETRLREMERYVTSDTFTLRSRFRQL
>SEQF1516_EDU85511.1 protein RecT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKQPPIAKADLQKTQGNRAPAAIKNNDVISFINQPSMKEQLAAALPRHMTAERMIRIATTEIRKVPALGNCDTMSFVSA
IVQCSQLGLEPGSALGHAYLLPFGNKNEKSGKKNVQLIIGYRGMIDLARRSGQIASLSARVVREGDEFNFEFGLDEKLIH
RPGENEDAPVTHVYAVARLKDGGTQFEVMTRKQIELVRSQSKAGNNGPWVTHWEEMAKKTAIRRLFKYLPVSIEIQRAVS
MDEKEPLTIDPADSSVLTGEYSVIDNSEE
>SEQF1516_EDU85512.1 mandelate racemase/muconate lactonizing enzyme family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTVKVFEEAWPLHTPFVIARGSRSEARVVVVELEEEGIKGTGECTPYPRYGESDASVMAQIMSVVPQLEKGLTREELQK
ILPAGAARNALDCALWDLAARKQQQSLADLIGITLPETVITAQTVVIGTPDQMANSASTLWQAGAKLLKVKLDNHLISER
MVAIRTAVPDTTLIVDANESWHAEGLAARCQLLADLGVAMLEQPLPAQDDAALENFIHPLPICADESCHTRSNLKALKGR
YEMVNIKLDKTGGLTEALALATEARAQGFSLMLGCMLCTSRAISAALPLVPQVSFADLDGPTWLAVDVEPALQFTTGELH
L
>SEQF1516_EDU85513.1 glutamate--putrescine ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METNIVEVENFVQQSEERRGSAFTQEVKRYLERYPNTQYVDVLLTDLNGCFRGKRIPVSSLKKLEKGCYFPASVFAMDIL
GNVVEEAGLGQEMGEPDRTCVPVLGSLTPSAADPEFIGQMLLTMVDEDGAPFDVEPRNVLNRLWQQLRQRGLFPVVAVEL
EFYLLDRQRDAEGYLQPPCAPGTDDRNTQSQVYSVDNLNHFADVLNDIDELAQLQLIPADGAVAEASPGQFEINLYHTDN
VLEACDDALALKRLVRLMAEKHKMHATFMAKPYEEHAGSGMHIHISMQNNRGENVLSDTEGEDSPLLKKMLAGMIDLMPS
SMALLAPNVNSYRRFQPGMYVPTQASWGHNNRTVALRIPCGDRHNHRVEYRVAGADANPYLVMAAIFAGILHGLDNELPL
QEEVEGNGLEQEGLPFPIRQSDALGEFIENDHLRRYLGERFCHVYHACKNDELLQFERLITETEIEWMLKNA
>SEQF1516_EDU85514.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELEEGLAAQLFFRRSKGVTLTDAGESFYQHASLILEELR
AAQEDIRQRQGQLAGQINIGMGASISRSLMPAVISRFHQQHPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHE
FTFEKLLEKQFAIFCRPGHPAIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQTPQVGVVCETFSACISLVAKSDF
LSILPEEMGCDPLHGQGLVMLPVSEILPKAAYYLIQRRDSRQTPLTASLITQFRRECGYLQS
>SEQF1516_EDU85515.1 Rac prophage; integrase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKLPTGVEIRGKYIRIWFMFRGKRCRETLKGWEVTNSNIKKAGNLRALIVHEINSGEFEYLRRFPQSSTGAKMVTTRVI
KTFGELCDIWTKIKETELTTNTMKKTKSQLKTLRIIICESTPISHIRYSDILNYRNELLHGETLYLDNPRSNKKGRTVRT
VDNYIALLCSLLRFAYQSGFISTKPFEGVKKLQRNRIKPDPLSKTEFNALMESEKGQSQNLWKFAVYSGLRHGELAALAW
EDVDFEKGVVNVRRNLTILDMFGPPKTNAGIRTVTLLQPALEALKEQYKLTGHHRKSEITFYHREYGRTEKQKLHFVFMP
RVCNGKQKPYYSVSSLGARWNAAVKRAGIRRRNPYHTRHTFACWLLTAGANPAFIASQMGHETAQMVYEIYGMWIDDMND
EQVAMLNARLS
>SEQF1516_EDU85516.1 IS629 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU85517.1 AP endonuclease, family 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIGTQNQAFFPENILEKFRYIKEMGFDGFEIDGKLLVNNIEEVKSAIKETGLPVTTACGGYDGWIGDFIEERRLNGLKQ
IERILEALAEVGGKGIVVPAAWGMFTFRLPPMTSPRSLDGDRKMVSDSLRVLEQVAARTGTVVYLEPLNRYQDHMINTLA
DARRYSVENNLKHVQIIGDFYHMNIEEDNLAQALHDNRDLLGHVHIADNHRYQPGSGTLDFHALFEQLRADNYQGYVVYE
GRIRAEDPAQAYRDSLTWLRTC
>SEQF1516_EDU85518.1 IS66 family element, orf1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLDAAAEQPESLAEDPETLSISCEVTFRHGTLRFNGNVSEKLLTLLIQELKR
>SEQF1516_EDU85519.1 tail assembly protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTAAEAIRALSLQMPGFRRQMNEGWYQTRIPTASQNRSPAPVFVVMSGEYLLDKKEEIIQ
>SEQF1516_EDU85520.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDAVVALLFAADACLVASSFEADADDADDAAELADDAAAVFEDSALVSDAFAFVSDVFAAEAELAAALACSVASPAFVVA
VEADDAALSADFPAAVALAEACPALVDAALADNAAAVFEPAAAEALCSAAVSEDLAFVSDVLAAFAELPAAVAEEAALLA
LEAALVSDDFAASFEADASLAEEAASDAFVVAVDAEVAADCCDTAAFVSDVFAAPALVAAALFEDSAAAALFDASVAFVD
AVPALEDAD
>SEQF1516_EDU85521.1 spermidine/putrescine ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGQSKKLNKQPSSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGEFLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNED
ITHVPAENRYVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIAR
AVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPREIYEEPK
NLFVAGFIGEINMFNATVIERLDEQRVRANVEGRECNIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRER
NYKGMTLESVVELENGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK
>SEQF1516_EDU85522.1 phage terminase, small subunit, P27 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARPPKAPAYLDDIAVKQWREKSRQLAERGDLTPADWSNLELYCVNYSIYRKAVADLAARGFSIVNSQGGESRNPALSAK
SDAERVMIKMASLLGFDPISRRKNPPETEEEDELDRLE
>SEQF1516_EDU85523.1 phage prohead protease, HK97 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGEKIMKSMEIRSSEITTSASNTLTGYVVRWDNLSELLWGEFYEKFQRGAFTEWLAAGNDVRGLYEHDHSMLLGRTRSGT
LKLEEDETGLRFELTPPDTSTGRDVIELVKRGDISGMSFGFRSRKDVWDTTTDPCVRTVLVAELYEITVTSVPAYPDSGV
ELARRSLYEQHPEKMPRADNRRWWADLAGV
>SEQF1516_EDU85524.1 hypothetical protein ECH7EC4501_4503 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGSLPSVVLLLWFNMLEIFFLLIFLSVYSYSFIRILAKKILF
>SEQF1516_EDU85525.1 phage tail assembly chaperone [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKDLKTLALARLSGFRHKTVKVPEWRNVSVVLREPSAEAWYLWQEVLNGDGEDDDTLSVVAKTRRNLEADVTLFCDVLC
DTDLQRVFTPDDREQVLAVYGPVHARLLRQALELIADAESARKK
>SEQF1516_EDU85526.1 spermidine/putrescine ABC transporter, permease protein PotB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVTIVGWLVLFVFLPNLMIIGTSFLARDDASFVKMVFTLDNYTRLLDPLYFEVLLHSLNMALIATLACLVLGYPFAWFL
AKLPHKVRPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYILLPFMVMPLY
SSIEKLDKPLLEAARDLGASKLQTFIRIIIPLTMPGIIAGCLLVMLPAMGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDW
PFGAATSITLTIVMGLMLLVYWRASRLLNKKATEIDN
>SEQF1516_EDU85527.1 Gp14 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFDRVSPLGDERGDIRNAQIVKAVFGAQGMNVALKDAMLCWGEDEDKPEVDPFAALEDALSLAAMS
>SEQF1516_EDU85528.1 putative phage head-tail adaptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAISAGRLTQMISVLNPVLTRNAAGEMTEEWVSCGKIHADIRGRSSRERMQSGAEMAQAEIRIWVRGQSGREITAASRLH
VLSGPWRDHVLNVVGVPVPDATGGRLEILCRLGGEK
>SEQF1516_EDU85529.1 prophage minor tail protein Z [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIKGLEQAVENLSRISKTAVPGASAMAINRVASSAISQSASQVARETRVRRKLVKERARLKRATVKNPQARIKVNRGDL
PVIKLGNARVVLSRRRRRKKGQRSSLKGGGSVLVVGNRRIPGAFIQQLKNGRWHVMQRVAGKNRYPIDVVKIPMAVPLTT
AFKQNIERIRRERLPKELGYALQHQLRMVIKR
>SEQF1516_EDU85530.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIVIPFPQWGKSSNRNDVRCGCLDGLRGHYDHSQKQHIRCFSVPRPPQIEEVESINQLPRRLPQIEVPENISGLTIKLA
SN
>SEQF1516_EDU85531.1 phage minor tail protein U [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHTELRAAVLDALEKHDTGATFFDGRPAVFDEADFPAVAVYLTGAEYTGEELDSDTWQAELHIEVFLPAQVPDSELDAW
MESRIYPVMSDIPALSDLITSMVASGYDYRRDDDAGLWSSADLTYVITYEM
>SEQF1516_EDU85532.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATPLIRVMNGHIYKVPNRRKRKPELKPSEIPTLLGYTASLVDKKWLRLAARRNHG
>SEQF1516_EDU85533.1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDDGEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWD
NVFELFLAEYKAGRTPNPDILCNKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSH
EQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQPGKIITVDGDEIGEHQGLMYHTL
GQRKGLGIGGTKEGTEEPWYVVDKDVENNILIVAQGHEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCT
VKALDDDRIEVIFDEPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPI
>SEQF1516_EDU85534.1 DNA-binding response regulator PhoP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHLPDIAIVDLGLPDEDGLSLICRWRSNDVSLPILVLTA
RESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMET
LIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGYLFELR
>SEQF1516_EDU85535.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWRFLALSAGESQIIHVTAWTEREARSRCPSGCVAVFAARIRQGVCHA
>SEQF1516_EDU85536.1 tail length tape measure protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEPVGDLVVDLSLDAARFDEQMARVRRHFSGTESDAKKTAAVVEQSMSRQALAAQKAGISVGQYKAAMRMLPAQFTDVA
TQLAGGQSPWLILLQQGGQVKDSFGGMIPMFRGLAGAITLPMVGATSLAVATGALAYAWYQGNSTLSDFNKTLVLSGNQA
GLTADRMLVLSRAGQAAGLTFNQTSESLSALVKAGVSGEAQIASISQSVARFSSASGVEVDKVAEAFGKLTTDPTSGLTA
MARQFHNVTAEQIAYVAQLQRSGEEAGALQAANEAATKGFDDQTRRLKENMGTLETWADRTARAFKSMWDAVLDIGRPDT
AQEMLIKAEAAFKKADDIWNLRKDDYFVNDEARARYWDDREKARLALEAARKKAEQQSQQDKNAQQQSDTEASRLKYTEE
AQKAYERLQTPLEKYTARQEELNKALKDGKILQADYNTLMAAAKKDYEATLKKPKQSGVKVSAGDRQEDSAHAALLTLQA
ELRMLEKHAGANEKISQQRRDLWKAESQFAVLEEAAQRRQLSAQEKSLLAHKDETLEYKRQLAVLGDKVTYQEHLNALAQ
QADKFAQQQRAKRAAIDAKNRGLTDRQAAREATEQRLKEQYGDNPLALNNVMSEQKKTWAAEDQLRGSWMAGLRSGWSEW
EESATDSMSQVKSAATQTFDGIAQNMAAMLTGSEQNWRSFTRSVLSMMTEILLKQAMVGIVGSIGSAIGGGASASGGTAI
QAAAAKFHFAAGGFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYATGGYVGTPGSMADSRSQASGTFEQN
NHVVINNDGTNGQIGPQALKAVYDVARKAAMDVVTGQMRDGGLFSGGGR
>SEQF1516_EDU85537.1 sensor histidine kinase PhoQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSFDKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDK
QSPTMTLIYDENGQLLWAQRDVPWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVA
VNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSLRPIEALAKEVRELEEHNRELLN
PATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLTHSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGY
YLHRASMHGGTLLSRELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACKYCLEFVEI
SARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAREITKQYEGKIVAGESMLGGARMEVIFGRQH
STPKDE
>SEQF1516_EDU85538.1 bacteriophage lambda tail assembly protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTGAEAIRALATQLPVFRQKLSDGWYQVRITGRDVSTSGLTAQLHETLPDGAVIHIVPRVAGAKSGGVFQIVLGAAAIA
GSFFTAGATLAAWGAAIGAGGMTGILFSLGASMVLGGVAQMLAPKARTPRTQTTDNGKQNTYFSSLDNMVAQGNVLPVLY
GEMRVGSRVVSQEISTADEGDGGQVVVIGR
>SEQF1516_EDU85539.1 phage tail assembly protein T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDGELSFALKLAREMGRPDWRAMLAGMSSTEYADWHRFYSTHYFHDVLLDMHFSGLTYTVLSLFFSDPDMHPLDFSLLN
RREADEEPEDDVLMQKAAGLAGGVRFGPDGNEVIPASPDVADMTEDDVMLMTVSEGIAGGVRYG
>SEQF1516_EDU85540.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLPQDGIKLHRGNFTAVGQQIQTYLEDGKCFRMVLKPWRERRSLSQNALSHMWYSEISEYLISRGKSFATSAWVKDALK
HTYLGYETKDLVDVVTGEITTIQSLRHTSDLGTGEMYVFLCKVEAWAMNIGCHLTIPQSCEFQLLRDKQEA
>SEQF1516_EDU85541.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPQHSDIEIAWYAAIQQEPNGWKTVTTQFYIQEFSEYIAPLQDAVDLEIATEEERSLLEAWNKYRVLLNRVDTSVARKR
TA
>SEQF1516_EDU85542.1 Gp11 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEADLYPHLAHLAGGQVYPYVVPLLDGRPSVALPWVVFSLISSVSADVMGGQAESSVSVQIDVYAGTVTQARQIRQDAR
EAIMLLAPGSVSEMQDYIPENRCYRATLEFQVTV
>SEQF1516_EDU85543.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLKYPGLTDSGKTRTKFMRGDIYRDQYGGTVMIKGVEERRVTYHREGYEYDCVMPVYQFRRDFSLVQAAPRSKPTSREK
ARANIQEIKKMLNVFRGKK
>SEQF1516_EDU85544.1 single-strand binding protein family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAQIAAYGRLVDDPQVKQTSKGTPMTLARMAVSLPCSQAQDGQATLWLSVIAFGKQADFLAKHQKGDVASVSGTMQVSQ
WTGQNGETRQGYQVIADSVISARAARPGGNRRKTTGTQGNQPPAGGDDPYGDGIPF
>SEQF1516_EDU85545.1 major tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSALYERSQLTQVMISSAPATAETMEKAEYLRLDCTIKEVQFTAGQKQDIDVTTLCSTEQENINGLGASSEISMSGNFYL
NQAQNALRDAYDNDTVYAFKVQFPSGKGFKFLAEVRQHTWSSGTNGVVAATFSLRLKGKPVSYVVPLAFVKNPDKTLTVN
TGALLTMSVSVNGGTPPYKHAWKKDGQPVEGQTTDTFSKANTQSGDKGAYTCEVTDSAEQPQSITSDACTVTVNGAGG
>SEQF1516_EDU85546.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKTFRVFASAVNPLGHTIGIAQNVKAVNVQTAIAAVRSESSEYGLSQVIISAVYELKEVH
>SEQF1516_EDU85547.1 phage minor tail protein G [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLKTESFEHNGVTVTLSELSALQRIEHLALMKRQAEQAESDSNRKFTVEDAIRTGAFVVAMSLWHNHPKKTQMPSMNEA
VKQIEQEVLTTWPAEAISHAENVVYRLSGMYEFVVNDAPEQAEDAGPAEPVSAGKCSTVS
>SEQF1516_EDU85548.1 tail length tape measure protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLRELIIKISANSQSFQSEIQRASRMGSEYYRTLQNGGRQAAAAAREQRRALAELNSQLTEIRGSAVGMAGAFAGAFA
SGHLISLADEWSSVNARLKQASQSSDEFASSQKVLMDISQRTGTAFSDNAALFARSAASMREYGYSAGDVLKVTEAISTG
LKISGASTAEAGSVITQFSQALAQGVLRGEEFNSVNESGDRIVRALAAGMGVARKDLKAMADDGKLTADKVVPALISQLG
ILRDEYAAMPETVSSSITKVENAFMAWVGGANEASGVTKTLSGMLNGVAGQIDNVATAVGALVAVGVARYFGNMASGAMS
ATAGLVTAARNEVALAEAQFRGTQIATARARAAVYRAQQAVAAARGTEMQIAAEARLAATQERLNRNIAARSAAQNALNS
TTAVGSRLMSGALGLVGGVPGLVMLGAAAWYTLYQNQEQARESARQYALTIDEIAHKTPSMSLPEASDNEGRTRAALTEQ
NRLIDEQASRVKSLQEKIAGYQYVLANPGWTTGDGFMINHLTSVKTVTEGLAQATEQLAVEQSRLAQMQEKAQSIQDVLA
GLEDRRVALIRQQAAEQNKVYQSMLVMNGQHTEFNRLLGLGNELLQQRQGLVNVPLRLPQATLDDKQQSALTKTERELAL
SRLKGEEKERVRLGYAADDLGFVGDPYQEARQRYISNALEAWRNNEANKPKSRGGKSETEKAEDSFSRLLKQQKEQLALV
GQNTELAKLKYQTALGELKTLTEMQKQELLRNATLIDQQKIREQLRSREETLKNENAAARASNDAELLGYGQGERARERM
RELQQIRDSFRQKDADLQSQYQTGDISEDFYRQALAQNAQYLSERLKDQAVFYAESDVQRADWQKGLQEGFSNWVDNASD
YASQAAQLATEGISGMVNNITEMLNGNKVEWRSWASSVLQEISKVLMNAAIVNGIKTAANGMSGAGGFLGSIGDWLGGAV
ANAKGGVYTSANLSAYSNSIVDTPTYFAFAKGAGLMGEAGPEAIMPLTRAADGSLGVRAVGSMNGSAGLVYSPVYHIAIQ
NDGANGQIGPEAAGSLVQLIDQRVQAVMLSMRRDGGMLSG
>SEQF1516_EDU85549.1 phage major capsid protein, HK97 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRIIELRQQKTAIKNQMRDMLENAEKENRSLNDAEGAKFDELRAKAESLDKDISRLEAIADEERSKPGKSSQTTDPAEL
RNYILTGETRALSTGVPADGGYTVIPELNTEIMRMLTDESTMRRICTVKKISSNEFKQLVSAGGATVNHGEEGKTREQTS
TPQINEVSIKLYPVYAYPRTTQEIVDFSDVDILSWLTGEIGDTFTETEESDLVVGDGDKKAKGFLSVPRAEKNDKERDFG
TLQVIKPSESLAWTSADPLIDLKFALRKKYRKNAVWVVNSTTAAKLQKVKNANGDYIWRDRLQAGDPDTLLGLPVEYLEF
MPDNVIALGDFKRGYYIVDHETGVRTRPDNLTEPGFIKIFTQKYLGGGVVDSNAIKILELPQDDD
>SEQF1516_EDU85550.1 protein YciF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQIKSVEDIFIHLLSDTYSAEKQLTKALSKLSRSAYSDKLTAAFQSHLDETHGQIERIDQVVDSEDGLKLKRIKCAAMEG
LIEEANEVIESTDKNEVRDAALIAAAQKVEHYEIASYGTLVTLAEQLGYKKAAKLLKETLEEEKATDVKLTDLAFNNVNK
KAQDNS
>SEQF1516_EDU85551.1 hypothetical protein ECH7EC4501_4490 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRQQLRAKVRRNLQQRALRQRQNGQRILHPPWRLRMRARRKRG
>SEQF1516_EDU85552.1 antirepressor protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSIAKAQNDFTIFKFGDSEIRVINKCGEPWFVAKDVCDALALTNSRKALTALDDDEKGVTLSYTLGGEQNLSIVSESGM
YTLVLRCRDAVNKGSVPHKFRKWVTAEVLPSIRKHGEYVKGKKTTVEERTPLRDAVNMLVGKKGLRNDDAYNMVHQRFGI
DSIDELSIEQIPLAVEYIHRVVLEGEFIGKQEKSTNELSAKEANSLVWLWDYANRSQALFRELYPALKQIQSNYSGRCYD
YGHEFSYVIGMARDVLINHTRDVDINEPDGPTNLSAWMRLKNKELPPSPHHY
>SEQF1516_EDU85553.1 tail assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQTESAILAHARRCAPAESCGFVVSTPEGERYFPCVNISGEPEAYFRMSPEDWLQAEMQGEIVALVHSHPGGLPWLSEA
DRRLQVQSDLPWWLVCRGTIHKFRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHREDDWWRHGQNLYLDNLEAT
GLYQVPLSSAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRRTHSLWRHRAWRASAFTGICNDL
AAASTFV
>SEQF1516_EDU85554.1 lipoprotein bor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKMLLATALALLITGCAQQTFTVQNKPAAVTPKETITHHFFVSGIGQKKTVDAAKICGGAENVVKTETQQTFVNGLLGF
ITLGIYTPLEARVYCSQ
>SEQF1516_EDU85555.1 major tail protein V [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTPNPLAPVKGAGTTLWVYNGNGDPYANPLSDNDWSRLAKVKDLTPGELTAESYDDSYLDDEDADWAATGQGQKSAGDT
SFTLAWMPGEQGQQALLAWFNEGDTRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTA
ATGMTVTPASTSVVKGQSTTLTVAFQPEGATDKSFRAVSADKTKATVSVSGMTITVKGVAAGKVNIPVVSGNGEFAAVAE
INVTAS
>SEQF1516_EDU85556.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIKFYLHGKEIPAERILDTPEWKDYRPKYSGSTYKYS
>SEQF1516_EDU85557.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPMKFDEILKQRDKYHADNMETMSINDYRAFLETGALIEKDQHGFVRCALSGEMLAVNPEQIDALIEFLKGIRD
>SEQF1516_EDU85558.1 phage protein, HK97 gp10 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIETLLDFSGLEDISRDLQLLSGAENNRVLREATRAGANVLKEEVVSRAPVRRGKLRRNVVVLSRCSRDGGMESGVHIRG
VNPDTGNSDNTMKADNPRNAFYWRFVEMGTVNMPPHPFVRPAFDVRSEQAAQVAIARMNRAIDEVLRR
>SEQF1516_EDU85559.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEREQNRLIRGLIRQRDAWKTQETGHKDKASGRAERITAKRLTDRDREVMECFRNR
>SEQF1516_EDU85560.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIHNNSRGGDMEKEVSRILVRIPQSLKDAITGKAKEECRSFNSEVM
>SEQF1516_EDU85561.1 phage DNA packaging protein Nu1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEVNKKQLADIFGASIRTIQNWQEQGMPVLRGGGKGNEVLYDSAAAIKWYAERDAEIENEKLRREVEELRQDSETDLQPG
TIEYERHRLTRAQADAQELKNARDSAEVVETAFCTFVLSRIAGEIASILDGIPLSVQRRFPELENRHVDFLKRDIIKAMN
KAAALDELIPGLLSEYIEQSG
>SEQF1516_EDU85562.1 putative head-tail adaptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISSKEAISSGAELAIGTVRIWIRYRKDINATSRIKVSTGPLAGRVLNIIGQPLPDVARTRLEILCREGAEK
>SEQF1516_EDU85563.1 P4 alpha zinc-binding domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLAPNVKKQPRGIKHKDTEVIIFAGSDAWAHAKQWQEQDGPASGDNVPPVWLGEQQLSELDKLQIVPEGRKSVRIFRAG
HLAPVMIKAIGQKLAAAGVQDANFYPEGMHGQKVENWREYLARERQNLSDGLVIEFPVKKKDTGSHSDDELKPRVESRAD
GVFWVTPKVDKQSGEIIRPETWLCSPLELLGTGTIGKEHYRVMRWKKTANHEVITMAIPCGGIGDRDGWRLLKDHGLNVT
TNGKYRAILADWMQLSGSHEEWQLSTTTGWHFGAYIMPDGSIIGESEKPILFTGKSAAINGYSVAGTADGWRDSVARLAG
GNASMILGVATSLAAPLIGLVGADGFGVHLFEQSSAGKTTTQNIASSLWGEPDAQRLTWYGTALGIANEAEAHNDGLLPL
DEIGQAGNAREVSTSAYTLFNGSGKLQGAKDGGNREIKHWRTVAISTGEMDVETFLKSEGIKVKAGQLVRLLNVPMEKAT
KFHEYSNGKEHADALKDAWTANHGAAGREWVKWLAGHQQEAKDTVRECRERWRNLIPESYGEQVHRVGERFAILEAALVL
SGHVTGWVVQECRDAIQHNFNAWVKEFGTGNREFKQMVEQAEAFLSSFGFSRYLPHPNTDERDLPIKELAGYRKGSIRNE
DDEMRYYTFPHVFESEIAKGFNPAHFARALDAAGMLEKGSDRRYKKKALGKIGGKQHVFYVLMFQPDDED
>SEQF1516_EDU85564.1 tail assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYSNILAHARRCAPAESCGFVVRTPEGERYFPCVNISGEPEDYFRMSPEDWLRAEMQGEIVALVHSHPGGLPWLSEADR
RLQIKSALSWWLVCRGEIHKFRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIDMPDFEREDDWWRNGQNLYLDNMAVTGF
YRVPLSSAQAGDILLCCFGASVANHAAIYCGNGELLHHLPEQLSKRERYSEKWQRRTHSAWRHRHWHVSAFTGIYNDLAA
ASACT
>SEQF1516_EDU85565.1 protease 7 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVSQLDWKFNNAAIIKGAINWDL
MPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYS
FTARGGSYIYSSEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVEASDNDEHYDPGKRIT
YRSKVKDQNYYSVSVNAGYYVTPNAKVYVEGTWNRVTNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF
>SEQF1516_EDU85566.1 isocitrate dehydrogenase, NADP-dependent [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQ
DVWLPAETLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIY
AGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGA
FKDWGYELAREEFGGELIDGGPWLKVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGI
GIAPGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYDFERLMEGA
KLLKCSEFGDAIIKNM
>SEQF1516_EDU85567.1 YciE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRIEHYHDWLRDAHAMEKQAEKMLESMASRIENYPELRSRIEQHISETKNQLSQLESILDRNNISRSVIKDSMSKMAAF
GQSIGGIFPSDEIVKGSISGYVFEQFEIACYTSLLAAAKNAGDTASVPIIEAILNEEKQMAEWLLNHIPDTTEQFMVRSE
IDGVEAKK
>SEQF1516_EDU85568.1 gpW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRQEELAAARAALHDLMTGKRVATVQKDGRRVEFTTTSVSDLKKYIAELEVQTGMTQRRRGPAGFYV
>SEQF1516_EDU85569.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEAELLGLIRRVSGISQQADEQTTQPDSVTAENYARVVAEVMCRDGIQLNDVDMRNIRIRVLEMLAYNRRVELHREKEK
ITYHWKKPERLRR
>SEQF1516_EDU85570.1 putative phage terminase, large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAWNKYAEDVKTGKIPACKRLKQAVKRYFSDLKSPLYTFDREVVERFIAFSRVCPHVKGPMRGRPIELEPWQQFAFACI
LGFKVKATGRRKYTSAFIEVPRKNAKSTTAAILANWFLIMENGQQDIYTAAVSRDQARIVFDDARQMCLLSRPLRRRVNI
QAHKVIHPKSNSLLKPLAAKAATIEGTTPSLAIVDEYHLHPDNGVYSALELGMGARPEGLLFAITTSGSNVVSACKQHYD
YCCQILDGEEVNESMFVLIYELDDESEVDDPAMWIKANPNIDVSVDREKLASTIQKARGIPSQWVEMMTKRFNIWCQGAT
PWMGNGAWAECAGTFTEEDLHGQECYAGLDLSSTSDISSVCYAFPVGKTIMLISRHYLPEFQLQNPANKNRAVYRQWAKA
GWIRTTPGDCIDYDRIRDDIMQDAEKFHIRLVGFDTWNATHLRTQLQGAGFEVEPFPQTYLRFSPAAKSFEVFVNRRVIV
HRGDPVLSWSMSNVVMQSDANANIKPNKKKSPNKIDPSVAALMAFGTFQAEHEDFAFDISDSHRQKLEEFSGV
>SEQF1516_EDU85571.1 phage minor tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEIKTLHLVPREGMQVSEKPSVVRVRFGDGYEQRRPTGLNPQLKTFQAVFRVTDESTRRWLDEFLSWHGGYRAFLWRPP
KHNRTVRVVCREWSVTDNARYSDFSCTIEQVVN
>SEQF1516_EDU85572.1 phage minor tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTFRWKVKPGMDVASAPSVRKVRFGDGYSQRAPAGLNADLKTYSVTLSVPRWEATALESFLAEHGGWKAFLWTPPYEWR
QIKVTCAKWSSRVSMLRVEFSAEFEQVVN
>SEQF1516_EDU85573.1 hypothetical protein ECH7EC4501_4452 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLVFVYSFVPSRLLRKQIAIRLLLYIQDSVIVIVFLNKN
>SEQF1516_EDU85574.1 IS2 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDSARALIARGWGVSLVSRCLRVSRAQLYVILRRTDDWMDGRRSRHTDDTDVLLRIHHVIGELPTYGYRRVWALLRRQAE
LDGMPAINAKRVYRIMRQNALLLERKPTVPPSKRAHTGRVAVKESNQRWCSDGFEFCCDNGERLRVTFALDCCDREALHW
AVTTGGFNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRSPESNGIAENFVKTI
KRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREYLRQRACNGLSDNRCLEI
>SEQF1516_EDU85575.1 putative regulatory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILQAAIDEEKSPRSIEGFAQQESEKFREALLKTLSSMYGEDKKPT
>SEQF1516_EDU85576.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKIRYLQGTHDARAGDIRDVAQPCAEVLVRLGKAEYITARRPAGQKKKRDAEHGECGTFCGEPEKTRNQDVT
>SEQF1516_EDU85577.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFESYMAERLRHRWMRLRLYRFPGSVLTDYRILKNYAKTLKGAAA
>SEQF1516_EDU85578.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKAIAYMRFSSPGQMSGDSLNRQRRLIAEWLKVNSDYYLDTITYEDLGLSAFKGKHAQSGAFSEFLDAIEHGYILPGTT
LLVESLDRLSREKVGEAIERLKLILNHGIDVITLCDNTVYNIDSLNEPYSLIKAILIAQRANEESEIKSSRVKLSWKKKR
QDALESGTIMTASCPRWLSLDDKRTAFVPDPDRVKTIELIFKLRMERRSLNAIAKYLNDHAVKNFSGKESAWGPSVIEKL
LANKALIGICVPSYRARGKGISEIAGYYPRVISDDLFYAVQEIRLAPFGISNSSKNPMLINLLRTVMKCEACGNTMIVHA
VSGSLHGYYVCPMRRLHRCDRPSIKRDLVDYNIINELLFNCSKIQPVENKKDANETLELKIIELQMKINNLIVALSVAPE
VTAIAEKIRLLDKELRRALVSLKTLKSKGVNSFSDFYAIDLTSKNGRELCRTLAYKIFEKIIINTDNKTCDIYFMNGIVF
KHYPLMKVISAQQAISALKYMVDGEVYF
>SEQF1516_EDU85579.1 IS66 family element, transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQLDKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTL
TGRVYDPAVQRPLRQTRTRKPFPESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
DAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELRRSLLSGWVDACCRLLSPLEEALHGYVMT
DGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNAGSALAPAVWFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELY
RNGGITEAACWAHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWLREKMKT
LSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKNFLFFGSDHGGERGALLYSLIGTCKLNDVDP
ESYLRHVLGVIADWPVNRVSELLPWRIALPAE
>SEQF1516_EDU85580.1 HNH endonuclease family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPWQPLRRCTEPGCNRRVKSGKCEEHRRAAWRAEDARRGHRRARGYSRQWDKYRAMYLSKNPLCVRCLEKGIYTPAVVVD
HIIPIDGGDDVLFWPEWNHQPLCQACHNQKTKWLDPATKSKRAAGGFREEEERAANRNNWMYDADE
>SEQF1516_EDU85581.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTGKEAIIHYLGTHKSFCAQDVAAVTGATVTSINQAAAKMARAGILVVDGKVWRTVYYRFATREEREGKVSTNLIFKECR
QSAAMKRVLRVYKRTSMGTQ
>SEQF1516_EDU85582.1 site-specific recombinase, phage integrase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRALNKLSDTQLRKINGTPAQKTAFLNDGGNLSVRHSTSGLLTWYFTYRAGTGRGAPPERIKLGNYPDLSLKSAREKAA
QCRAWLAEGKNPRHELNYTVQEALKPVTVGDALTYWLESYAKENRVDYAALKKRLNNHVIQHIGAMPLDKCELRHWLACF
DQVAKRTPVTAGFLLQTCKQALKFCRRRRYAISNVLDDMSVADVGKKPDISERVLSTKELGELLQALDKKIFSPYYIALI
RLLIVFGCRTVELRLSEISEWDFTEMLWTVPKEHSKTKVAIFRPIPEAILPFVTQLVEQNRHTGLLLGEVKQETSVSQYG
RLAHRRLNHPHWSLHDIRRTFTTMLNDLGVDPHVVEQLTGHQMPGMQRVYNHSRYLDAKRNALDMWTERLGILAGTHENV
TTLPVARRK
>SEQF1516_EDU85583.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEELITLEEVKLHCRIDGDEEDQLISGYIAASLEACQIHIGRRFDDGLEFTPAIKIGCMMFIAHLYENRQIVADNAKTR
VPMTIGALWTAYRDVGVY
>SEQF1516_EDU85584.1 putative envelope protein of prophage CP-933X [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQVAIFKEIFDQVRKDLNCELFYSELKRHNVSHYIYYLATDNIHIVLENDNTVLIKGLKKVVNVKFSRNTHLIETSYDR
LKSREITFQQYRENLAKAGVFRWVTNIHEHKRYYYAFDNSLLFTESIQNTTQIFPR
>SEQF1516_EDU85585.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNYYDITLALAGICQSARLVQQLAHQGHCDADALHVSLNSIIDMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQG
LNAELTRYTLSLMVLKRKLSSAKGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQS
PQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL
>SEQF1516_EDU85586.1 putative membrane protein of prophage CP-933X [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALEDASTTKKGIVQLSSATNSTSESLAATPKAVKAAYELANGKYTAQDATTAQKGIVQLSNATNSTSEMLAATPKSVKA
AYDLANGKYTAQDATTAQKGIVQLSSATNSASETLAATPKAVKAANDNANGRVPSARKVNGKALSSDITLTPKDIGTLNS
TTMSFSGGAGWFKLATVTMPQASSVVSITLIGGAGFNVGSPQQAGISELVLRAGNGNPKGITGALWQRTSTGFTNFAWVN
TSGDTYDIYVAIGNYATGVNIQWDYTSNASVTIHTSPAYSANKPEGLTDGTVYSLYTPSEQFYPPGAPIPWPSDTVPSGY
ALMQGQTFDKSAYPKLAAAYPSGVIPDMRGWTIKGKPASGRAVLSQEQDGIKSHTHSASASSTDLGTKTTSSFDYGTKST
NNTGAHTHSVSGTAASAGNHTHSVTGASAVSQWSQNGSVHKVVSAASVNTSAAGAHTHSVSGTAASAGAHAHTVGIGAHT
HSVAIGSHGHTITVNAAGNAENTVKNIAFNYIVRLA
>SEQF1516_EDU85587.1 replication protein O [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRNAVLNLSIFHQLLVFLAVMRKTYGFNKKLDWVSNEQLSELTGILPHKCSAAKSVLVKRGIFIQSGRNTGINNVVSEW
STLPESGKKNKVYLKEVNLPESGKKSLPKSGKGVYPNQVNTKDKLTKDNIKPFSSENSGESSDQPENDLPVVKPDAAIQS
GSKWGTAEDLTAAEWMFDMVKTIAPSARKPNFAGWANDIRLMRERDGRNHRDMCVLFRWACQDNFWSGNVLSPAKLRDKW
TQLEINRNKQQAGMIASKPKLDLTNTDWIYGVDL
>SEQF1516_EDU85588.1 phage terminase large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNISNSQVNRLRHFVRAGLRSLFRPEPQTAVEWADASYYLPKESAYQEGRWETLPFQRAIMNAMGSDYIREVNVVKSARV
GYSKMLLGVYAYFIEHKQRNTLIWLPTDGDAENFMKTHVEPTIRDIPSLLALAPWYGKKHRDNTLTMKRFTNGRGFWCLG
GKAAKNYREKSVDVAGYDELAAFDEDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVRGTCQIERAASESPHFMRFHVAC
PHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEHNACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPD
SVTFHIWTAYSPFTTWVQIVKDWMKTKGDTGKRKTFVNTTLGETWEAKIGERPDAEVMAERKEHYSASVPDRVAYLTAGI
DSQLDRYEMRVWGWGPGEESWLIDRQIIMGRHDDEQTLLRVDEAINKTYTRRNGAEMSVSRICWDTGGIDPTIVYERSKK
HGLFRVIPIKGASVYGKPVASMPRKRNKNGVYLTEIGTDTAKEQIYNRFTLTPEGDEPLPGAVHFPNNPDIFDLTEAQQL
TAEEQVEKWVDGRKKILWDSKKRRNEALDCFVYALAALRISISRWQLDLSALLASLQEEDGAATNKKTLAEYARALSGED
E
>SEQF1516_EDU85589.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEQINIALDQKGSGNFSAWVIEACRRRLTSEKRAYTSIKSDEE
>SEQF1516_EDU85590.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTALLTLEEIKAHLRVDHDADDEMLMDKVRQATAVLLAYIQGSRDKVISEDGELIPGEALTRMKGAAMRLTGMLYRNPDL
AEREDLVQGELPFSVSVLIYDLRCPTVL
>SEQF1516_EDU85591.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRTRRDRTEPKYKALDITELALKVAIRTIDRHVGEGYAKEHPDLISAFMTTAAANFATLTEREIAEAEQVTTINVKTGE
VES
>SEQF1516_EDU85592.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEHRGGAGNFAEDRQKASDAGRKGGQHSGGNFKNDPQRASEAGKKGGQNSHGGGRKSDS
>SEQF1516_EDU85593.1 TnpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVRRLRFSGPKTSIICSPMTSLKTSIKTITYLSDTGCLEIQGASLVIYTTNAIESLNSVIRHAIKKRKVFPTDDSVKKVV
WLAIQAASQKWTMPLRDWRMAMSRFIIEFGDRLDGHF
>SEQF1516_EDU85594.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKEQSADDPSVDLIRVKNMLNSTISMSYPDVVIACIEHKVSLEAFRAIEAALVKHDNNMKDYSLVVD
>SEQF1516_EDU85595.1 minor capsid protein C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAELRNLPHIASMAFNEPLMLEPAYARVFFCALAGQLGISRLTDAVSGDSLTAGEAPAALALSGDDDGPRQARSYQVMN
GIAVLPVSGTLVSRTRALQPYSGMTGYNGIIARLQQAASDPMVDGILLDMDTPGGMVAGAFDCADIIARVRDIKPVWALA
NDMNCSAGQLLASAASRRLVTQTARTGSIGVMMAHSNYGAALEKQGVEITLIYSGSHKVDGNPYSHLPGDVRETLQSRMD
ATRRMFAQKVSAYTGLSVQAVLDTEAAVYSGQEAIDAGLADELVNSTDAITVMRDALDARKSRLSGGRMTKETQSTTVSA
TASQADVTGVVPATEGENASAAQPDVNAQITAAVAAENSRIMGILNCEEAHGREEQARVLAETPGMTVETARRILAAAPQ
SAQARSDTALDRLMQGAPAPLAAGNPASDAVNDLLNTPV
>SEQF1516_EDU85596.1 putative portal protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRTRKNQKSGRDVREAGWTSLFQAVAEPFSGAWQQGVKADPEAVLSFHAVFACISLISQDIAKMRLRLMQTDAHGIRRE
TRRGDIARLCRRPNAQQNRIQFFELWLNAKLRHGNTVVLKIRNARGQIKELRILDWSRVEPLVADDGEVFYRITPDRNCG
ITEAVTVPAREVIHDRFNCFFHPLIGLPPVYAAGLAATQGHHIQENSTSFFRNGGRPSGVIEIPGSITEENAKKLKSNWD
SGYTGENAGKTAILSNGAKYNPTTFSPVDAQTVEQLKMTAEIVCSVFRVPAYKIGVGQPPSSDNVEALEQQYYSQCLQTL
IESIELLLDEALETGENESTEFDVTTLLRMDSERRMKTLGDAVKNTLLTPNEARKRENLPPLAGGDALYLQQQNYSLEAL
SRRDAREDPFASAGKTVSSQLPDGASDGNKAISETEHDAVKAMFRGDTEKMTERELSIIRALGEEFSTVLADLQRTFEEK
IAAQAQTFEEKLASQSVVLQKCVTGDDVRPMLEQMVKEAVSHIPVPRDGRDYDPDVLQKAVNDAVANIPVPADGKSITPD
DVRPMLEQMVKEAVSHIPVPRDGRDYDPDVLQKAVNDAVAKIPVPADGKSITPDDVHPMLEQMVKEAVSHIPVPRDGRDY
DPDVLQKAVNDAVAKIPVPADGKSITPDDVHPMLEQMVKEAVSHIPVPRDGRDYDPDVLQKAVLEAVSALPAPQDGRDAT
ALEILPAIDDQKSFPRGSYATHQGGLWRAYEKTYGMRGWECLVDGVADIDVSMTGERSFSVVVRQSSGQRTEKTFSLPVM
LYRGVFRIGETYHPGDTVTWGARCGTATV
>SEQF1516_EDU85597.1 antitermination protein Q [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTQYLQYVREQLIVATADLSGATKGQLEAWLEHAQFDTGTYKRKKPRILDEVTGRMITLDNPPISGKQSYAKGSSIALV
SQVEFSTSSWRRAVLSLEEHQKAWLLWSYSESVRWEHQVTITQWAWSEFKTLLGTRKIAGKTLERLKKLIWLAAQDVKNE
LAGRKTYEYQELASLVGVTSKNWSETFTERWVAMKHIFLQLDSQALLLLTKTRSKQKTTFSQQDIAKLD
>SEQF1516_EDU85598.1 prophage lambda integrase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAASPRSHKISIPNLYCKLDKRTGKVYWQYKHPLSGRFHSLGTDENEAKQVATEANTIIAEQRTRQILSVNERLERMKGR
RSDITVTEWLDKYNSIQEDRLQHNELRPNSYRQKGKPIRLFREHCGMQHLKDITALDIAEIIDAVKAEGHNRMAQVVRMV
LIDVFKEAQHAGHVPPGFNPAQATKQPRNRVNRQRLSLPEWQAIFDSVSRRQPYLKCGMLLALVTGQRLSDICNLKFSDI
WDDMLHITQEKTGSKLAIPLNLKCDALNITLREVISQCRDAVVSKYLVHYRHTTSQANRGDQVSANTLTTAFKKAREKCG
IKWEQGTAPTFHEQRSLSERLYREQGLDTQKLLGHKSRKMTDRYNDDRGKDWIIVDIKTA
>SEQF1516_EDU85599.1 ribosomal large subunit pseudouridine synthase E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKTSFRNHQVKRFSSQRSTRRKPENQPTRVILFNKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTN
NGALQARLTQPGKRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRERKSIPTSWLKI
TLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDNLANGEWREATE
>SEQF1516_EDU85600.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEITLHEAAERAHQTEIICRLLEVYPDKLNDGDISALAGLLAKLSGSVALWLIDERAERYEK
>SEQF1516_EDU85601.1 hypothetical protein ECH7EC4501_4436 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIFSKFASGEHRGNQPNPLILSETAIGGIRRGNLLIFPITQNCVAE
>SEQF1516_EDU85602.1 DNA packaging protein FI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKDELIARLRSLGEQLNRDVSLTGTKEELALRVAELEEELDDTDETAGQDTPLSRENVLTGHENEVGSAQPDTVILDTS
ELVTVVALVKLHTDALHVTRDEPVAFVLPGTAFRVSAGVAAEMTERGLARMQ
>SEQF1516_EDU85603.1 EmrE protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPYIYLGGAILAEVIGTTLMKFSEGFTRLWPSVGTIICYCASFWLLAQTLAYIPTGIAYAIWSGVGIVLISLLSWGFFG
QRLDLPAVIGMMLICAGVLVINLLSRSTPH
>SEQF1516_EDU85604.1 replication protein P [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIAAQMVNFDREQMRRIANNMPEQYDEKPQVQQVAQIINGVFSQLLATFPASLANRDQNELNEIRRQWVLAFRENGIT
TMEQVNAGMRVARRQNRPFLPSPGQFVAWCREEASVIAGLPNVSELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNL
YQNMRANALTDAELRRKAADELTCMTARINRGETIPEPVKQLPVMGGRPLNRAQALAKIAEIKAKFGLKGASV
>SEQF1516_EDU85605.1 bacteriophage lysis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRITAIISALLICIIVCLSWAVNHYRDNAITYKAQRDKNARELKLANVAITDMQMRQRDVAALDAKYTKELADAKAEND
ALHDDVAAGRRRLHIKAVCQSVREATTASGVDNAASPRLADTAERDYFTLRERLITMQKQLEGTQKYINEQCR
>SEQF1516_EDU85606.1 catalase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRHVKKLQYTVRVSEPNPGLANLLLEQFGGPQGELAAACRYFTQGLSDEDAGRRDMLMDIATEELSHLEIIGSLVGMLN
KGAKGALAEGTENEAELYRSLTQNGNDSHITSLLYGGGPALTNSAGVPWTAAYVDTIGEVTADLRSNIAAEARAKIIYER
LINVTDDPGVKDTLAFLMTREAAHMLSFEKALHSIRNTFPPGKLPPLEKYKNVYYNMSEGEDVRGSWNSDENFDYVSDPV
SAVDGGDGKASINLSTKQEAMIKAMATRLKSHEDINPVTGAELAEGEPQTKINSKN
>SEQF1516_EDU85607.1 tail fiber assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFRMSEQPRTIKIYNLLTGTNEFIGEGDAYIPPHTGLPANSTYIAPPDIPAGFVAVFNSDESSWHLVEDHRGKTVYDVA
SGDALFISELGSLPENVTWLSPEGEFQKWNGTAWVKDAEAEKLFRIREAEETKNSLMQVASEHIAPLQDAVDLEIATEEE
ASLLEAWKKYRVLLNRVDTSTAPDIEWPVIPEV
>SEQF1516_EDU85608.1 peptidase T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLNNVVTKNEGDYMDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEEMGLINVTLSEKGTLMATLPANV
PGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGDIALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIA
EIMTALAVLQQKNIPHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIVGNNVHPGT
AKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMHYIIRDFDRKQFEARKRKMMEIAKKVGKGLH
PDCYIELVIEDSYYNMREKVVEHPHILDIAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVT
LEGMEKAVQVIVRIAELTAQRK
>SEQF1516_EDU85609.1 putative protease encoded within prophage CP-933X [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKIITHFKVVLTLLLPVTVSAQQIQWQSCMASQFNHWFGEEKPSPDLLCGYLSVPLKYTDTGGDASYEKKSQVKLALTK
LPAKSKHKGSILIISGGPGLPGINPYINFDWPVTNLRESWDIIGFDPRGVGQSTPTINCRQSDTETQENITEKQQVLNKI
NACIHNTGAEVIRHIGSNEAVYDIDRIRQALGDKQLTAVAYSYGTQIAALYAERFPYNVRSIVLDGVVDIDDLEDNFTWQ
LKQAQSYQETFDRFASWCARTKSCPLSSDRDKAITQFHELLSKLHHKPLLDSKGENISSDELISLTTDLLLWRSSWPTLA
TAIRQFSQGIVSNEIETALSAPIASEESSDASGVILCVDQGDEQLTPEERKFRKEALANAFPAINFDNGRSDSPDFCELW
PIHSDLNKTRLKNTVLPSGLLFVAHKYDPTTPWINARKMAEKFSSPLLTINGDGHTLALTGVNLCVDKAVVHHLITPQKI
ENIYCPGNSEAEIQ
>SEQF1516_EDU85610.1 phage major capsid protein E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLFLRDFFMSMYTTAQLLAANEQKFKFDPLFLRLFFRESYPFTTEKVYLSQIPGLVNMALYVSPIVSGEVIRSRGGSTS
EFTPGYVKPKHEVNPQMTLRRLPDEDPQNLADPAYRRRRIIMQNMRDEELAIAQVEEMQAVSAVLKGKYTMTGEAFDPVE
VDMGRSAANNITQSGGTEWSKRDKSTYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVREKLDTRRGSHSELETA
VKDLGKAVSYKGMYGDVAIVVYSGQYVENGVKKNFLPDNTMVLGNTQARGLRTYGCIQDADAQREGINASARYPKNWVTT
GDPAREFTMIQSAPLMLLADPDEFVSVQLA
>SEQF1516_EDU85611.1 hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETLVEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFL
RFLFAIELEQICPTQPHDSDIDCCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI
>SEQF1516_EDU85612.1 enterobacterial Ail/Lom family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKLYAAILSAAICLAVSGAPAWASEHQSTLSAGYLHARTSAPGSDNLNGINVKYRYEFTDTLGLVTSFSYAGDKNRQLT
RYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
GAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF
>SEQF1516_EDU85613.1 gp13 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHEKESLAGAFWLVLLIIAGWGGLVRYLIDVKQSKATWSWINALAQIVVSGFTGVIGGLISIESGFSIYMILATAGISGA
MGSVALTYFWERLTGVKNAKS
>SEQF1516_EDU85614.1 bacteriophage lambda head decoration protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSKETFTHYQPLGNSDPAHTATAPGGLSAKAPAMTPLMLDTSSRKLVAWDGTTDGAAVGILAVAADQTSTTLTFYKSGT
FRYEDVLWPEAASDETKKRTAFAGTAISIV
>SEQF1516_EDU85615.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKITNYILPTSRTHGSFSTIKSWDTMNYIKHLIRHTNDPIFEEQFYKITQSHIDFDKRAKDEKNDTINIYDNFFYSSNDD
LDSKIRSMLNNLYEKSLTFRRIINYYVKEINLSDYGFLKCKILPAYAYNYEMENDAPPKILIPIDHNLNFIDAKYNGETY
RGNEEFAINLFLQHILHNDIQEQTSIDLYTSIINKELDSNRKSYNNEIFNNFSFDKSVKLNSYNYIADDIEQVIDKGSKV
QLEVYNLLSEEKIFEHKIMNNWTRSIKNILTTYLFMSSGAVTARNVQTFSPTINNESRIRLPRALPVGHPYPEEHKASGF
SPFMMGGLSGDILPEILTGNGPSIFFNGKHNNQHDGAFGKIIDFTQNGNKISAKDKEIIKRYIFDKINVLIKEYFIRTGK
NSHTPFEVFIKERLFNQYDIFKTLARDILAHPLVIYDAGYKNYHESLNAAIAINSRPLQEIHYGDVLYHYHKNDISLGVD
TLYGRESFDIVLDAMNVYRKSKKMRVISNNEMKKSIKISELVIHNIIKKGLTNCLLKKDVLNARYDLIRDILRYSLNIRQ
GIKHDDVNRIAENIIKKYGITEGMNPKPRNARISKELLLLAVDRQIEWAKKHFITKDVLENVVSKCDLSSIFNVNKVLQN
TILEFVHEINNISSARWMSKSEKNNKQKEAIEKFKKEVSHMNGGQQFIWGFDKVIQEGLSGLIELSIDINDSTNHRDKSS
LSPDGRAVLHFLGTIWNMAMGAVPGYNALSGVSSILHSAIVKESSNICDYIQGAVRIGMDFVPGTRSDLHSRSLQIKYEA
LKHIEKNINDNIIYHPSNNANFYSVIESIDGNDFIYNEKQSKILEMKQDRGGNRYSAVDLNSSKYGYYEKVGGGFYRYIE
SFNPISSETPNKIVYKGESVDLTKEPNSELYSGRYSINNKQVNVYFFRDADGTFYKSEGLHGGGVIRYIDKPYSQLREGD
IGYDEDLLDIYDDSPVLEDTLPALSSEIVPTPEHSIKQIYSKIKEGHIELSDSDIILCRGTTGIQAENIVEYKTAGGLPD
SNPNVKAPDEYMAQQQVRIGRILPEYTSDLSVADRFSREHYLIVVKVKAKYITRGSVTESGWVIDKTAPVEPLAIIDRTF
GMKENISMVNASK
>SEQF1516_EDU85616.1 cupin family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLAMESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWS
LLVQAVNHWHEPTAALMRPFRELPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMKQHCPHPDLL
QVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYVLQRELGGNYYSDPDVPPRAHPA
DVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSRHELDIAPPEPPYQPDEIYDALKQGDVLVRLGGLRVLRIGDDVYT
NGEKIDSPHRPALDALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG
>SEQF1516_EDU85617.1 phage Head-Tail Attachment [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADFDNLFDAAIARADETIRGYMGTSATMTSGEQSGAVIRGVFDDPENISYAGQGVRVEGSSPSLFVRTDDVRQLRRGDT
LTIGEENFWIDRISTDDGGSCHLWLGRGVPPAVNRRR
>SEQF1516_EDU85618.1 adenylosuccinate lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWLQKLAAHAAIKEVPAFAADAIGYLDAIVANFSEEDAA
RIKTIERTTNHDVKAVEYFLKEKVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAVQ
YRDIPLLSRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHIAAYPEVDWHQFSEEFVTSLGIQ
WNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVWGYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAV
LQHLASKLPVSRWQRDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTVMRRYGIEK
PYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAITMVDELK
>SEQF1516_EDU85619.1 phage portal protein, HK97 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWPFRRKKEQRSMTLDEFMALAGTSNTGAGEYVSSGTAESLPAVMNAVTVISEAVATMPCYLYLVRNEKGKEAREWLDSH
PVDHILNERPNAWQTPYQFKRMMVRHCLLNGNAYAVIQWGRDGFPVALHPYPPQSVNVEQTGEHNWRYCITDAYTGNTHN
YLPWEVLHLRYSTDDGFMGRSPVTICRESLGLGLAQQRHGASVMRDGMMAAGVITSGEWLDGVKGKQALAALERYKGARN
AGKTPILEGGMSYQQLGMSNQDAEWLASRRFTIEDIARMFNVSPIFLQEYSNSTYSNFSEASRAFLTMTMRPWLANFEQQ
IKNALLVASPVPGIRYQVEFDSADLLRATPGERFATYERGIKSGVMCPNEAREREGLSPRDGGDEFSQAWKQEVKISEGE
KPE
>SEQF1516_EDU85620.1 phage minor tail protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNEKGEPVTWQGRQYQPYPIQGSGFELNGKGTSTRPTLT
VSNLYGMVTGMAEDLQSLVGGTVVRRKVYARFLDAVNFVNGNSDADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
AVFPGRIMLANTCTWTYRGDECGYHGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNVGNFGGFLSINKLSQ
>SEQF1516_EDU85621.1 lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNLNPQRKAFLDMLAWSEGTDNGRQPTRNHGYDVIVGGELFTDYSDHPRKLVTLHPKLKSTAAGRYQLLSRWWDAYRKQ
LGLKDFSPKSQDAVALQQIKERGALPMIDRGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVRESEV
>SEQF1516_EDU85622.1 crossover junction endodeoxyribonuclease RusA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTYSITLPWPPSNNRYYRHNRGRTHISAEGQAYRDNVARIIKGSMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFD
ALTKAGFWLDDAQVVDYRVVKMPVTKGGKLELTITELGNE
>SEQF1516_EDU85623.1 phage portal protein, lambda family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKMSTIPTLLGPDGMTSLREYAGYHGGGSGFGGQLRAWNPPGESVDAALLPNFTRGNARADDLVRNNGYAANAIQLHQDH
IVGSFFRLSHRPSWRYLGIGEEEARAFSREVEAAWKEFAEDDCCCIDVERKRTFTMMIREGVAMHAFNGELFVQATWDTR
PSRLFRTQFRMVSPKRISNPNNTSDSRNCRAGVQINDSGAALGYYVSEDGYPGWMPQKWTWIPRELPGGRASFIHVFEPV
EDGQTRGANVFYSVMEQMKMLDTLQNTQLQSAIVKAMYAATIESELDTQSAMDFILGANSQEQRERLTGWIGEIAAYYAA
APVRLGGAKVPHLMPGDSLNLQTAQDTDNGYSVFEQSLLRYIAAGLGVSYEQLSRNYAQMSYSTARASANESWAYFMGRR
KFVASRQASQMFLCWLEEAIVRRVVTLPSKARFSFQEARSAWGNCDWIGSGRMAIDGLKEVQEAVMLIEAGLSTYEKECA
KRGDDYQEIFAQQVRETMERRAAGLKPPAWAAAAFESGLRQSTEEEKSDSRAA
>SEQF1516_EDU85624.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADLRKAARSRECQVRIPGVCNGNPETSVLAHIRLTGLCGTGTKPPDLIATIACSACHDEIDRRTHFVDAAYAKECALEG
MARTQVIWLKEGVIKA
>SEQF1516_EDU85625.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVQFSTGFPVPSFSTPEIFTAIFTPQKSPPEPAGCHNTVLPG
>SEQF1516_EDU85626.1 phage minor tail protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNIHEESLNESVKSEQSPRVVLWEIDLTVQGGERYFFCNELNEKGEAVTWQGRQYQVYPIDGSGFEMNGKGSSARPSLT
VSNLFGLVTGMAEDLQSLVGATVVRRRVYARFLDAVNFVAGNPEADPEQELRDRWVVEQMSELTAMTASFVLATPTETDG
ALFPGRIMLANTCMWDYRGDECGYHGPAVADEFDNPTTDIRKDRCSKCMRGCEMRGMVANFGGFLSINKLSQ
>SEQF1516_EDU85627.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPVITINYTINYTDRCTKGYNVKQAGTRKITNLFIIKNIMNNLKHYETAKNTN
>SEQF1516_EDU85628.1 IS66 family element, orf2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPS
ARDGKVFLTQAQLAMLLEGIDWRQPKRLLTSLTML
>SEQF1516_EDU85629.1 hypothetical protein ECH7EC4501_4437 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRDVVGAILRFALISVSYRANFHSLWKLGRINGLGLNHLRNHK
>SEQF1516_EDU85630.1 host specificity protein J [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPVDGLKSVLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEG
FESSGSETVLGTEVKYDTPITRTITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
SQYLASVVVDNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALVGVQVDSEQFGSQKVSRNYHLRG
RILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCLWDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTE
PRITCNAYLTTQRKAWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGASFRYSFSALKDRHNAVE
VNWIDPDNGWETATELVEDTQAILRYGRNVTKMDAFGCTSRGQAHRAGLWLIKTELLETQTVDFSVGAEGLRHVPGDVIE
ICDDDYAGISIGGRVLAVNSQTRTLTLDREITLPSSGTTLISLVDGSGNPVSVEVQSVTDGVKVKVSRVPDGVAGYSVWG
LKLPTLRQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGDLSGTVNGVTPPAVQHLTAEVTADSGEYQVLAR
WDTPKVVKGVSFLLRLTVAADDGSERLVSTARTTETTYRFTQLALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRI
ELTPGYFQITATPHLAVYDPTVQFEFWFSETRIADIRQVETSARYLGTALYWIAASINIKPGHDYYFYIRSVNTVGKSAF
VEAVGRASDDAEGYLDFFKGKITESHLGKELLEKVDLTEDNASRLDEFSKEWKDANDKWNAMWGVKIEQTKDGKHYVAGI
GLSMEDTEEGKLSQFLVAANRIAFIDPANGNETPMFVAQGNQIFMNDVFLKRLTAPTITSGGNPPAFSLTPDGKLTAKNA
DISGSVNANSGTLNNVTINENCQIKGKLSANQIEGDIVKTVSKSFPRTSTYASGTITVRISDDQKFDRQVMIPPVLFRGG
KHENFNSNNQQSYWYSTCRLRVTRNGQEIFNQSTTDAQGVFSSVIDMPAGQGTLTLTFTVSSSGANNWTPTTSISDLLVV
VMKKSTAGISIS
>SEQF1516_EDU85631.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPTSQLRPTGTFCSYSAETSADIKSEITPIQIEEARASGRLYIKDCDIEYLPQLPNEITSVTIENCNNLTTLTGLPVNT
QNLSVINCEKLQITDMPSTVKNLHIELTDSPFIHFISEGIECLTVCHCYISGVPESVRYLEIKGSATDSIKNVPNGLSSL
SINSYNPENQARIDNLISPSLKTLSLTGCSNIILPEKLPESVTSVTIHAEQKTTWNIGVEGMPDGLDLDLQNVLLSPDVV
KAKNITFQGNALDVALHFREGDIVYGLSSPREKLVNSIKLVNDFSKKDIITQNTLTNAVWDPRTPRKYKQDPLIKRALNE
HERGIKFKQHLKNHNNYNVTMADLSVYNRDKLWAKTSKAGLEFQTLTRNKTVIFCADELVNSLKLIANKSEGYGQSITAS
ELRWIYRNKDNNQIMKNIKFYLHGKEIPAERILDTPEWKDYRPKYSGSTYKYS
>SEQF1516_EDU85632.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPTTNISVNSGVISFESPVDSPSNEDVEVALEKWCAEGEFSENRHEVASKILDVISTNGETLSISEPITTLPDLLPGSL
KELVLNGCTELKSINCLPPNLSSLSMVGCSSLEVINCSIPENVINLSLCHCSSLKHIEGSFPEALRNSVYLNGCNSLNES
QCQFLAYDVSQGRACLSKAELTADLIWLSANRTGEESAEELNYSGCDLSGLSLVGLNLSSVNFSGAVLDDTDLRMSDLSQ
AVLENCSFKNSILNECNFCYANLSNCIIRALFENSNFSNSNLKNASFKGSSYIQYPPILNEADLTGAIIIPGMVLSGAIL
GDVKELFSEKSNTINLGGCYIDLSDIQENILSVLDNYTKSNKSILLTMNTSDDKYNHDKVRAAEELIKKISLDELAAFRP
YVKMSLADSFSIHPYLNNANIQQWLEPICDDFFDTIMSWFNNSIMMYMENGSLLQAGMYFERHPGAMVSYNSSFIQIVMN
GSRRDGMQERFRELYEVYLKNEKVYPVTQQSDFGLCDGSGKPDWDDDSDLAYNWVLLSSQDDGMAMMCSLSHMVDMLSPN
TSTNWMSFFLYKDGEVQNTFGYSLSNLFSESFPIFSIPYHKAFSQNFVSGILDILISDNELKERFIEALNSNKSDYKMIA
DDQQRKLACVWNPFLDGWELNAQHVDMIMGSHVLKDMPLRKQAEILFCLGGVFCKYSSSDMFGTEYDSPEILRRYANGLI
EQAYKTDPQVFGSVYYYNDILDRLQGRNNVFTCTAVLTDMLTEHAKESFPEIFSLYYPVAWR
>SEQF1516_EDU85633.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNNKLATSELRSLANSAISLNNAANEVMNMWLQSLVNNERDESTARLILAVSELLDSSTSKIESISEKINGLSGHAIGE
>SEQF1516_EDU85634.1 glutaredoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRITIYTRNDCVQCHATKRAMENRGFDFEMINVDRVPEAAEALRAQGFRQLPVVIAGDLSWSGFRPDMINRLHPAPHAAS
A
>SEQF1516_EDU85635.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHVNQSYFRYGDKHKDGCGIHDPRYKNNHTSNDERKHNSPPAPVISLLKIDVKPRGGVKNARNIKNENHKDEKKGNEHP
VSSSSIKPVVDYYINNSNHNEQLSIPPYGTRSYKDTFQLIFYKNNIRYYKPAIYYGVAQSNIRLHEDSDKHCITFLARDK
KTQKPFTLEIDVSDWNKSQKDVFWKEYEKQRKEADRYYKGLKDKRNAKKYLTVFFFGMPDENDKFLFKTNHFKLVYVAFL
GKFESSYNDSNYYIENDLSVSSLNEQPISLSDIDHKNHEYNIETSLDFSSPLPEPEPEPEPEPEPEPEPEPEPEPEPEPE
PEPEPEPIRSSLKENTETVEMNSKVWGRLKKIITFFKK
>SEQF1516_EDU85636.1 NAD(+) kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIAHELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAT
RTLARYDIKVIGINRGNLGFLTDLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI
EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSARPLVINSSSTIRLRFSHRRNDL
EISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYSYFNTLSTKLGWSKKLF
>SEQF1516_EDU85637.1 chorismate mutase/prephenate dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSENPLLALREKISALDEKLLALLAERRELAVEVGKAKLLSHRPVRDIDRERDLLERLITLGKAHHLDAHYITRLFQLI
IEDSVLTQQALLQQHLNKINPHSARIAFLGPKGSYSHLAARQYAARHFEQFIESGCAKFADIFNQVETGQADYAVVPIEN
TSSGAINDVYDLLQHTSLSIVGEMTLTIDHCLLVSGTTDLSTINTVYSHPQPFQQCSKFLNRYPHWKIEYTESTSAAMEK
VAQAKSPHVAALGSEAGGTLYGLQVLERIEANQRQNFTRFVVLARKAINVSDQVPAKTTLLMATGQQAGALVEALLVLRN
HNLIMTRLESRPIHGNPWEEMFYLDIQANLESAEMQKALKELGEITRSMKVLGCYPSENVVPVDPT
>SEQF1516_EDU85638.1 putative inner membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALTTISPHDAQELIARGAKLIDIRDADEYLREHIPEADLAPLSVLEQSGLPAKLRRDQIIFHCQAGKRTSNNADKLAAI
AAPAEIFLLEDGIDGWKKAGLPVAVNKSQPLPLMRQVQIAAGGLILIGVILGYTVNSGFFLLSGFVGAGLLFAGISGFCG
MARLLDKMPWNQ
>SEQF1516_EDU85639.1 phospholipid-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGLFNFVKDAGEKLWDAVTGQHDKDDQAKKVQEHLSKTGIPDADKVNIQIADGKATVTGDGLSQEAKEKILVAVGNISGI
ASVDDQVKTATPATASQFYTVKSGDTLSAISKQVYGNANLYNKIFEANKPMLKSPDKIYPGQVLRIPEE
>SEQF1516_EDU85640.1 CBS/transporter associated domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIILIIMVVISAYFSGSETGMMTLNRYRLRHMAKQGNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRL
YGDAGVAIATGVLTFVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIKTDIVVSGS
LSKEELRTIVHESRSQISRRNQDMLLSVPDLEKMTVDDIMVPRSEIIGIDINDDWKSILRQLSHSPHGRIVLYRDSLDDA
ISMLRVREAWRLMSEKKEFTKETMLRAADEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGD
FTTSMSPTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVVGTRVRIGEYDIDILDVQD
NMIKQVKVFPVKPLRESVAE
>SEQF1516_EDU85641.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKISSVVSSCYHLFSEHQQLSNETTMTNPVSRRIVHKEYGISLKSVPVWLATAKTPLALLNGRHTRSHSFIIAGTPGMG
SRSGAQYYAINSDDKRSRIDIDSLFLKKLNNVRNQNKFPIDVKETVIKLQGQKFTCIEDFYKRYNETRLKANTNIQQEQI
ADEVKSLTYLIPSEKKEMWIYKNNGKDNAKPNLGERDVRMFENISSDDTDKITGRKFSELGEYLYSGNVIKLSQLSIRYL
PNISSISLIETKQSLLLHRLYSDEVLQRNGTLIPTPLHEEKSIPADNIKTMLNNIPTYKMLPPFTETQGNCSSGAATFLR
KSGAEEKDILACSPRNYGLHHNIKTWDPLVRN
>SEQF1516_EDU85642.1 putative cytochrome C assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQRLEQRSPDAILLLFLIAQTVDITMPVFALLALVAYSVSLALIVPGLLQKNGGWRRMAIISAVIALVCHAIALEARILP
DGDSGQNLSLLNVGSLVSLMICTVMTIVASRNRGWLLLPIVYAFALINLALATFMPNEYITHLEATPGMLVHIGLSLFSY
ATLIIAALYALQLAWIDYQLKNKKLAFNQEMPPLMSIERKMFHITQIGVVLLTLTLCTGLFYMHNLFSMENIDKAVLSIV
AWFVYIVLLWGHYHEGWRGRRVVWFNVAGAVILTLAYFGSRIVQQLIS
>SEQF1516_EDU85643.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSSCIGVVMKDGALLRSSSLFIAYMGCLGWGSAYFYGWGTSFYYGFPWWIVGAGVDDVARSLFFAVIVIAIFLIGWGIG
VVFFFAVKRKHSMQELNVFRLYFAVELLFVPAIIEFSILRQKIQVPLLLLSAAIALAVTISIRSYGRFLSVSCFYDKPFI
KKHFFEIVMIAFVAYFWLFSFLTGYYKPQFKKEYEMINYNDGWYYVLARYDNCLVLSTSFNAGSKRFVIYQSAQDKNLQV
DIVRTRI
>SEQF1516_EDU85644.1 tRNA (guanine-N1)-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHDRHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGE
GAKVIYLSPQGRKLDQAGVSELATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVL
GHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWLRRPELLENLALTEEQARLLAEF
KTEHAQQQHKHDGMA
>SEQF1516_EDU85645.1 hypothetical protein ECH7EC4501_5805 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGQSNNTTINGGRQSIHDGGISTGTIIESGNQDVYKGGISNGTTIKGGASRVEGGSANGTLIDGGSQIVKVQGHADGTTI
NKSGSQDVVQGSLATNTTINGGRQYVEQSTVETTTIKNGGEQRVYESRALDTTIEGGTQSLNSKSTAKNTQIYSGGTQII
DNTSSSDVIEVYSGGVLDVSGGTATNVTQHDGAILKTNTNGTTVSGTNSEGAFSIHNHVADNVLLENGGHLDINAYGSAN
KTIIKDKGTMSVLTNAKADATRIDNGGVMDVAGNATNTIINGGTQNINNYGIATGTNINSGTQNIKSGGKADTTIISSGS
RQVVEKDGTAIGSNISAGGSLIVYTGGIAHGVNQETGSALVANTGAGTDIEGYNKLSHFTITGGEANYVVLENTGELTVV
AKTSAKNTTIDAGGKLIVQKEAKTDSTRLNNGGVLEVQDGGEAKHVEQQSGGALIASTTSGTLIEGTNSYGDAFYIRNSE
AKNVVLENAGSLTVVTGSRAVDTIINANGKMDVYGKDVGTVLNSAGTQTIYASATSDKANIKGGKQTVYGLATEANIESG
EQIVDGGSTEKTHINGGTQTVQNYGKAINTDIVSGLQQIMANGTAEGSIINGGSQIVNEGGLAENSVLNDGGTLDVREKG
SATGIQQSSQGALVATTRATRVTGTRADGVAFSIEQGAANNILLANGGVLTVESDTSSDKTQVNTGGREIVKTKATATGT
TLTGGEQIVEGVANETTINDGGIQTVSANGEAIKTTINEGGTLTVNDNGKATDIVQNSGAALQTSTANGIEISGTHQYGT
FSISGNLATNMLLENGGNLLVLAGTEARDSTVGKGGAMQNQGQDSATKVNSGGQYTLGRSKDEFQALARAEDLQVAGGTA
IVYAGTLADASVSGATGSLSLMTPRDNVTPVKLEGAIRITDSATLTIGNGVDTTLADLTAASRGSVWLNSNNSCAGTSNC
EYRVNSLLLNDGNVYLSAQTAAPATTNGIYNTLTTNELSGSGNFYLHTNVAGSRGDQLVVNNNATGNFKIFVQDTGVSPQ
SDDAMTLVKTGGGDASFSLGNTGGFVDLGTYEYVLKSDGNSNWNLTNDVKPNPDPNPNPNPNPKPDPKPDPKPDPKPDPT
PEPTPTPVPEKRITPSTAAVLNMAATLPLVFDAELNSIRERLNIMKASPHNNNVWGATYNTRNNVTTDAGAGFEQTLTGM
TVGIDSPNDIPEGIATLGAFMGYSHSHIGFDRGGHGSVGSYSLGGYASWEHESGFYLDGVVKLNRFESNVAGKMSSGGAA
NGSYHSNGLGGHIETGMRFTDGNWNLTPYASLTGFTADNPEYHLSNGMESKSVDTRSIYRELGATLSYNMRLGNGMEIEP
WLKAAVRKEFVDDNRVKVNNDGNFVNDLSGRRGIYQAGIKASFSSTLSGHLGVGYSHGAGVESPWNAVAGVNWSF
>SEQF1516_EDU85646.1 polyketide cyclase/dehydrase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILFVGFLLMEIVMPQISRTALVPYSAEQMYQLVNDVQSYPQFLPGCTGSRILESTPGQMTAAVDVSKAGISKTFTTRNQ
LTSNQSILMNLVDGPFKKLIGGWKFTPLSQEACRIEFHLDFEFTNKLIELAFGRVFKELASNMVQAFTVRAKEVYSAR
>SEQF1516_EDU85647.1 16S rRNA processing protein RimM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDYQPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDD
RDAANLLTNCEIVVDSSQLPQLEEGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFL
DGQVIKKVDLTTRSIEVDWDPGF
>SEQF1516_EDU85648.1 transcriptional regulator, ArsR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTELTQLQASAEQAAALLKAMSHPKRLLILCMLSGSPGTSAGELTRITGLSASATSQHLARMRDEGLINSQRDAQRILYS
IKNEAVNAIIATLKNVYCP
>SEQF1516_EDU85649.1 multidrug resistance protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSANAETQTPQQPVKKSGKRKRLLLLLTLLFIIIAVAIGIYWFLVLRHFEETDDAYVAGNQIQIMSQVSGSVTKVWADNT
DFVKEGDVLVTLDPTDARQAFEKAKTALASSVRQTHQQMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREEL
QHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRIVSPMTGYVSRRAVQPGAQISPT
TPLMAVVPATNMWVDANFKETQIANMRIGQPVTITTDIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLP
VRIELDQKQLEQYPLRIGLSTLVSVNTTNRDGQVLANKVRSTPVAVSTAREISLAPVNKLIDDIVKANAG
>SEQF1516_EDU85650.1 ribosomal subunit interface protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKEPQGFVADATINTPNGVLVASGKHEDMYTAINELINK
LERQLNKLQHKGEARRAATSVKDANFVEEVEEE
>SEQF1516_EDU85651.1 SsrA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVLLRDGEAFLFGANITPMAVASTHV
VCDPTRTRKLLLNQRELDSLYGRVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
>SEQF1516_EDU85652.1 ribonucleoside-diphosphate reductase, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATTTAECLTQKTMDYHALNAMLNLYDSAGRIQFDKDRQAVDAFMATHVRPNSVTFSSQQQRLNWLVNEGYYDESVLNRY
SRDFVITLFAHAHTSGFRFQTFLGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDETLALQLTDEMLSGRFQPA
TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLED
AFSYANQLGARQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDVERVYGK
PFADVAISQHYDELVADERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPVAGRINMSNLCSEILQVNSASEY
DENLDYARTGHDISCNLGSLNIAHTMDSPDFARTVETAVRGLTAVSDMSHIRSVPSIEAGNAASHAIGLGQMNLHGYLAR
EGIAYGSPEALDFTNLYFYAITWHALRTSMLLARERGETFAGFKQSRYASGEYFSQYLQGNWQPKTGKVGELFARSGITL
PTREMWAQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPAPFMTNENLALYQDAYE
IGAEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIYAWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL
>SEQF1516_EDU85653.1 transcriptional regulator, GntR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRYQDIARQLKTVIEQGKLKPGARLPSSRTWSQELGVSRSTVENAYAELVAQGWLVRRGQAGTFVSEQIHPQQSAVDVV
AFAGESQQPLPFQMGLPALDLFPRELWARVMGRRLRTQTRFDLALGDVCGEAALREAIVDYLRVSRGIDCQPEQVFITHG
YAASMALILHALAQPGDGMWMEDPGFPLIRPIVTRHGVEILPVPVDDNGLDVTSGIQNYPDARFALITPAHQSPLGVALS
LARRYQILEWAERSQAWIIEDDYDSEFRYHGKPLPALKSLDAPQRVIYAGTFSKALFPALRCAWLVVPVEQISQFRQQAS
LEPCAVPVLWQNTLADFIREGHFWRHLKKMRQHYAQRRQWIEQALTQQGFQVVPQKGGIQMVIKLAGNDVTFVHKANAAG
LAVQALSDWRIRSSEDGGLLLSFTNIVSESMARQVAQQLRSALN
>SEQF1516_EDU85654.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANDSWSGQDKAQHFIASAMLSAAGNEYSQHQGMSRDRSAMFGLMFSVSLGASKEFWDSRPEGSGWSWKDLAWDVAGAST
GYTVWQLTRH
>SEQF1516_EDU85655.1 chorismate mutase/prephenate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPIYVPEREASMLASRRAEAEALGVPPDLIEDVLRRVMR
ESYSSENDKGFKTLCPALRPVVIVGGGGQMGRLFEKMLTLSGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIG
KLPPLPKDCILVDLASVKNGPLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGRKPEAYQWFLEQIQVWGARLHRI
SAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQLLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRY
YKRFGEAIELLEQGDKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRQ
>SEQF1516_EDU85656.1 hypothetical protein ECH7EC4501_5839 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLRICAHIVLHDLLNSSAEPTCLPKRPACCDAGRSFFLL
>SEQF1516_EDU85657.1 GGDEF domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNDNSLNKRPTFKRALRNISMTSIFITMMLIWLLLSVTSVLPLKQYAQKNLALTAATMTYSLEAAVVFADGPAATETLA
ALGQQGQFSTAEVRDKQQNILASWHYTRKDPGDTFSNFISHWLFPAPIIQPIRHNGETIGEVRLTARDSSISHFIWFSLA
VLTGCILLASGIAITLTRHLHNGLVEALKNITDVVHDVRSNRNFSRRVSEERIAEFHRFALDFNSLLDEMEEWQLRLQAK
NAQLLRTALHDPLTGLANRAAFRSGINTLMNNSAARKTSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEFGGLRH
KAYRLGGDEFAMVLYGVQSESEVQQICSALTQIFNLPFDLHNGHQTTMTLSIGYAMTIAHASAEKLQELADHNMYQAKHQ
RAEKLVR
>SEQF1516_EDU85658.1 ribonucleoside-diphosphate reductase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLTVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMP
DALTPHEEAVLSNISFMEAVHARSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNMEKISLGQREELKSFAFDLLLELYDNELQYTDEL
YAETPWADDVKAFLCYNANKALMNLGYEPLFPAEMAEVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEYEDWNF
>SEQF1516_EDU85659.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU85660.1 HAD-superfamily hydrolase, subfamily IA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMIALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVR
SMLLDSVEPLPLVEVVKSWHGRRPMAVGTGSESAIAEALLAHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPT
QCVVFEDADFGIQAARAAGMDAVDVRLL
>SEQF1516_EDU85661.1 IS66 family element [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLDAAAEQPESLAEDPETLSISCEVTFRHGTLRFNGNVSEKLLTLLIQELKR
>SEQF1516_EDU85662.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKTNINLMERYLLLLDRFVDKLAESGFSEQRIIEQSYLFCAGFYIKYQSGIEKMTFSNREVVLTFLLLSYYSHINKLDD
DLINKERMKHVCSSLINFIVSNGSRTEKVYANEKRKYEASTLKRELSKKDKRKRYRL
>SEQF1516_EDU85663.1 RnfH family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPGKIAVEVAYALPKKQYLQRVTLQEGATVEEAIRASGLLELRTDIDLTENKVGIYSRPAKLSDSVHDGDRVEIYRPLIA
DPKELRRQRAEKSANK
>SEQF1516_EDU85664.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFNRPNRNDVDDGVQDIQNDVNQLADSLESVLKSWGSDAKGEAEAARSKAQALLKETRARMHGRTRVQQAARDAVGCADS
FVRERPWCSVGTAAAVGIFIGALLSMRKS
>SEQF1516_EDU85665.1 hypothetical protein ECH7EC4501_5806 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTASLSKEKNTPVFPEWIDFFIQPHFSALRLKNASFLCGISSFHHDVFDER
>SEQF1516_EDU85666.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKTTIKSGVIHTVKPANLKVASQRIKRLEAENEALKALNERYLEQFKVWLYNAHLKQITIEELNNPLPAKYL
>SEQF1516_EDU85667.1 hypothetical protein ECH7EC4501_5834 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDATLARLIMPTNHTAHFNNLSFIPYSSTSAIIDFQLNHHLMNKNNDQT
>SEQF1516_EDU85668.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKLIVPQWPLPKGVAACSSTRIGGVSLPPYDSLNLGAHCGDNPDHVEENRKRLFAAGNLPSKPVWLEQVHGKDVLNLTG
EPYASKRADASYSNTPGRVCAVMTADCLPVLFCNRAGTEVAAAHAGWRGLCAGVLEETVSCFADNPENILAWLGPAIGPR
AFEVGAEVREAFMAVDAEASTAFIQHGDKYLADIYQLARQRLANVGVEQIFGGDRCTYTENETFFSYRRDKTTGRMASFI
WLI
>SEQF1516_EDU85669.1 gab operon transcriptional repressor CsiR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTITSLDGYRWLKNDIIRGNFQPDEKLRMSLLTSRYALGVGPLREALSQLVAERLVTVVNQKGYRVASMSEQELLDIFDA
RANMEAMLVSLAIARGGDEWEADVLAKAHLLSKLEACDASEKMLDEWDLRHQAFHTAIVAGCGSHYLLQMRERLFDLAAR
YRFIWLRRTVLSVEMLEDKHDQHQTLTAAVLARDTARASELMRQHLLTPIPIIQQAMAGN
>SEQF1516_EDU85670.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQMEKITTGVSYTTSAVGTGYWLLQLLDKVSPSQWVAIGVLGSLLFGLLTYLTNLYFKIKEDRRKAARGE
>SEQF1516_EDU85671.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKKYELVVKGINNYPDKITVTVALEIGGYPSLLLPDVAISLDRTEGATLEFYEAEAKKQAKQFFMDVAAGLCEGDGPLP
EKRPVILEAQDVLITYRGKLPGIITGSLKTPPLA
>SEQF1516_EDU85672.1 glycine betaine/L-proline ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADQNNPWDTTPAADSAAQSADAWGTPATAPTDGGGADWLTSTPAPNVEHFNILDPFHKTLIPLDSWVTEGIDWVVTHFR
PVFQGVRVPVDYILNGFQQLLLGMPAPVAIIVFALIAWQISGVGMGVATLVSLIAIGAIGAWSQAMVTLALVLTALLFCI
VIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFALPPIIRLTILGINQVPADLIEA
SRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLALSMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIIL
DRLTQAVGRDSRSRGNRRWYTTGPVGLLTRPFIK
>SEQF1516_EDU85673.1 4-aminobutyrate transaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSNKELMQRRSQAIPRGVGQIHPIFADRAENCRVWDVEGREYLDFAGGIAVLNTGHLHPKVVAAVEAQLKKLSHTCFQV
LAYEPYLELCEIMNQKVPGDFAKKTLLVTTGSEAVENAVKIARAATKRSGTIAFSGAYHGRTHYTLALTGKVNPYSAGMG
LMPGHVYRALYPCPLHGISEDDAIASIHRIFKNDAAPEDIAAIVIEPVQGEGGFYAATPAFMQRLRALCDEHGIMLIADE
VQSGAGRTGTLFAMEQMGVAPDLTTFAKSIAGGFPLAGVTGRAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENL
LQKANDLGQKLKDGLLAIAEKHPEIGDVRGLGAMIAIELFEDGDHNKPDAKLTAEIVARARDKGLILLSCGPYYNVLRIL
VPLTIEDAQIRQGLEIISQCFAEAKQ
>SEQF1516_EDU85674.1 ribosomal protein L19 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFEGVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPV
VDSISVKRRGAVRKAKLYYLRERTGKAARIKERLN
>SEQF1516_EDU85675.1 alpha-ketoglutarate permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYNIFFAKRNKQKRPTKASDYGRRHNGMAESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFCSLYFAHIFF
PSGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCMMCFGSLVIACLPGYETIGTWAPALLLLARLF
QGLSVGGEYGTSATYMSEVAVEGRKGFYASFQYVTLIGGQLLALLVVVVLQHTMEDSALREWGWRIPFALGAVLAVVALW
LRRQLDETSQQETRALKEAGSLKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGMHANVASGIMTAALFVFM
LIQPLIGALSDKIGRRTSMLCFGSLAAIFTVPILSALQNVSSPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQVRALG
VGLSYAVANAIFGGSAEYVALSLKSIGMETAFFWYVTLMAVVAFLVSLMLHRKGKGMRL
>SEQF1516_EDU85676.1 lipoprotein, SmpA/OmlA family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVSKIRVGMTQQQVAYALGTPLMSDPFGTNTWFYVFRQQ
PGHEGVTQQTLTLTFNSSGVLTNIDNKPALSGN
>SEQF1516_EDU85677.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFSHRLFLLLILLLTGAPILAQEPSDVAKNVRMMVSGIVSYTRWPALSGPPKLCIFSSSRFSTALQENAATSLPYLPVI
IHTQQEAMISGCNGFYFGNESPTFQMELTEQYPSKALLLIAEQNTECIIGSAFCLIIHNNDVRFAVNLDALSRSGVKVNP
DVLMLARKKNDG
>SEQF1516_EDU85678.1 conserved DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNIFIFEPSNKNNPLDNVIKFIEFCKSTISNNNLTTSWESNKWKGLYRFTKFNSKNNLNSKECLDDSFINFAKAYMLHV
HSFNKSKTKHSTLSMLKIVEFVLLKINMEANVNYCNNSIYDECIRIASEKYSKAHAFAIGKELEKLSSFLNDNRMTNSFY
LFWVNPIRYRITQSWTGYDSSLEGHSRLPDIKSVIAIAEIFSKRDEQLSSRDIFTTSVLALLMCAPSRISEILALPADCE
ITECDGKGIQRYGLRFFSAKGYEGNIKWIPTLMIPVAKKAISRLKELSSQARLLAAEIQKNYSNSTKGTLKENIPPDLFW
YDREKKIKYSNALCLLTEGQLNQNKKEMSDKLFRPTTNFFKTDIIDSDYIKGYFNVFKRHGYINEDGSPYLLRTHQLRHL
LNTFAQINGMDEFSIARWSGRKLISQNVSYDHRSHLQMSKAIREKKLSVCVNEHRIKDIPVVDLNEFDSLSSGAVLVSKH
GYCKHSYAFKPCDNYPIKNSGLDNETISNIHDKILKRTLYDKNDGNINADKWYEFHKKIKKGE
>SEQF1516_EDU85679.1 gamma-aminobutyrate permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAGPAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFST
YADKAIGRWAGYTIGWLYWWFWVLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKV
IAILAFIFLGAVAISGFYPYADVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAEIVTIAAAESDTPEKHIVRATNS
VIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSVLELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGD
APAVMGKINRSKTPYVAVLLSTGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAEGSEIRLRM
WLYPWLTWLVIGFITFVLVVMLFRPAQQLEVISTGLLAIGIICTVPIMARWKKLVLWQKTPVHNTR
>SEQF1516_EDU85680.1 OmpA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKHLVAPLIFTSLILTGCQSPQGKFTPEQVAAMQSYGFTESAGDWSLGLSDAILFAKNDYKLLPESQQQIQTMAAKLAS
TGLTHARMDGHTDNYGEDSYNEGLSLKRANVVADAWAMGGQIPRSNLTTQGLGKKYPIASNKTAQGRAENRRVAVVITPP
>SEQF1516_EDU85681.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNWSVEHTREVKKWLDIDTYRGFEELPLIHLYHELLARTLFFKPYHEEFEAEAVRLYIDRIFTGKPFLITEKHLGYLTR
EDTLYQPPHFFLTTTERLAQLSIVGLRNSLFFWDGSDEYSVNREFLDSPVSEVLPKLFRDTVMVEIDLANGTDEEIAESL
KAALPQWRKVRGIEPDVTEAIRFGYGTIKKIINYRLLPMIDILVWSKLYKVRISEDRLSRLLYTDDDDEINTRLNHQIRD
TDKPLALKAASIPFIRQFNLFINKNSHLKKIRVSDVMKIADSD
>SEQF1516_EDU85682.1 ribosomal protein S16 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIASEKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNK
AA
>SEQF1516_EDU85683.1 multidrug resistance protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQQQKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISIPLTGWLAKRVGEVK
LFLWSTIAFAIASWACGVSSSLNMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGY
ISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVV
AVVAICFLIVWELTDDNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVIL
SPIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPPERLAAASS
LSNFTRTLAGSIGTSITTTMWTNRESMHHAQLTESVNPFNPNAQAMYSQLEGLGMTQQQASGWIAQQITNQGLIISANEI
FWMSAGIFLVLLGLVWFAKPPFGAGGGGGGAH
>SEQF1516_EDU85684.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISGSAIKDDDAFSDSQADRGLYLKGYAEGQKKTCQTDFT
YARGLSGKSFPASCNNVENASQLHEVWQKGADENASAIRLN
>SEQF1516_EDU85685.1 CDP-diacylglycerol--serine O-phosphatidyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKIASAKQRICIVALYLEQDDGGKGILNALYEAKRQRP
ELDVRVLVDWHRAQRGRIGAAASNTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVY
LHQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLFRQELRDAAYHFQGDADNDQLS
VTPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNLPAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGA
LPYLYEINLRRFLSRLQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHDPQLELAP
QREKELELIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRIL
>SEQF1516_EDU85686.1 S-Ribosylhomocysteinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISP
MGCRTGFYMSLIGTPDEQRVADVWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELA
LPKEKLQELHI
>SEQF1516_EDU85687.1 site-specific recombinase, phage integrase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENKCIESEQIFFAKMNRYSFKLSDKKWQLDKENCVYPHKVVDRMPTKMKLSYLKTLAYYASEYSSFYIQSINNLFYEWF
GAMTIDTIDDKAIYQLNVYLGSERNYKLNLIKAFIIKWKNLNYPGVEATAIRMLEKIKIIPNQTGDAVKRRDPNKGPLTE
AEFNNIINAVGKFYHEKKIQCFLYCYILLLAITGRRPLQLISLKAKDLIKNERGCFLNVPKVKQRKCFRKEFNMVMIEPF
LYDSLSMLINQNQAFVEDKFSVGISNYRGELPIFMNLDKITETKRIEDFLYDLTTDFFHMKNSVMSKLLKHFPSKFDVRS
ERTNSYIELNARRFRYTLGSRLANEGASIEVIAKALDHKSVNSSIIYIKNNPDNVYDIDKRLSAFFNPLSNILMGIEIEE
NKNFFIKFVSDAFFLLEDTKEDLKCLTCKKFNPWRAL
>SEQF1516_EDU85688.1 hypothetical protein ECH7EC4501_5741 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVCCLPLQYFQPCHYVSCRNPMLLSVAFVYFFWQRKCYTFVTYHYATLTMNLVSRKMVIEELKDKFLVRRTRMEVGKLG
KPYPLLNLAYVGV
>SEQF1516_EDU85689.1 signal recognition particle protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVALPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRN
ELVAAMGEENQTLNLAAQPPAVVLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFF
PSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETLFVVDAMTGQDAANTAKAFNEAL
PLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVGEKTEALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLA
SKLKKGDGFDLNDFLEQLRQMKNMGGMASLMGKLPGMGQIPDNVKSQMDDKVLVRMEAIINSMTMKERAKPEIIKGSRKR
RIAAGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGFPGR
>SEQF1516_EDU85690.1 H-NS histone family protein StpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEEEQQQRELAERQEKISTWLELMKADGINPEELLGNSS
AAAPRAGKKRQPRPAKYKFTDVNGETKTWTGQGRTPKPIAQALAEGKSLDDFLI
>SEQF1516_EDU85691.1 transcriptional repressor MprA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCA
LGSSRTNATRIADELEKRGWIERRESDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS
RLDQMEQDGVVLEAMS
>SEQF1516_EDU85692.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSPQSRLRHAVADTFAMVVYCSVVNMCIEVFLSGMSFEQSFYSRLVAIPVNILIAWPYGMYRDLFMRAARKVSPSGWIK
NLADILAYVTFQSPVYVAILLVVGADWHQIMAAVSSNIVVSMLMGAVYGYFLDYCRRLFKVSRYQQVKA
>SEQF1516_EDU85693.1 hypothetical protein ECH7EC4501_5779 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVINLLKICFLYCAFIFKYCFVEVGIWVMRKNIVLLY
>SEQF1516_EDU85694.1 co-chaperone GrpE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKIANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDI
EKAHKFALEKFINELLPVIDSLDRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV
ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA
>SEQF1516_EDU85695.1 YjhS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFKHYDVVRAASPSDLAEKLTHKLKEGWQPFGSPVAITPYTLMQVITAEGDVVVSGATEPDWYYVIVLAGQSNAMAYGE
GLPLPDSYDAPDPRIKQLARRSTVTPGGAACRYNDIIPADHCLHDVQDMSTLNHPKADLSKGQYGCVGQGLHIAKKLLPY
IPNNAGILLVPCCRGGSAFTQGAEGTFSADAGASQDSARWGVGKPLYQDLIARTKAALQKNPKNVLLAVCWMQGEFDMSA
ATHAQQPALFTAMLAQFRADLSVFNAQCHGGSAADVPWICGDTTYYWKNTYGTQYNTIYGAYKNRESEGVYFVPFMTDGN
GVNTATNAPAEDPDIPASGYYGAASRTNGNQVSSNRPTHFSSWARRSIIPDRMATAILNAAGRTSAFISGKAPEIKPSPG
GNTPSGPSADTSVRTISLLPAAGEAAAQGWSIKDGGIQLSDGVFKITRQSNKTWSLTHPVDDAITLLTQGGRLTCKFRLS
GALTNNQFGLGIYLYTDAPVPDGVAMTGTGNPFLMSYFTQTTDGRVNLMHHRKAGNTKLGEFGDYGNDWQTLELVFTAGS
ATVTPKLNGVAGPAFQVIKDSLTLGLNALTLTDVTKNAAYGVEIESLVLEINAPASS
>SEQF1516_EDU85696.1 glycine betaine/L-proline ABC transporter, periplasmic glycine betaine-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRHSVLFATAFATLISTQTFAADLPGKGITVNPVQSTITEETFQTLLVSRALEKLGYTVNKPSEVDYNVGYTSLASGDAT
FTAVNWTPLHDNMYEAAGGDKKFYREGVFVNGAAQGYLIDKKTADQYKITNIAQLKDPKIAKLFDTNGDGKADLTGCNPG
WGCEGAINHQLAAYELTNTVTHNQGNYAAMMADTISRYKEGKPVFYYTWTPYWVSNELKPGKDVVWLQVPFSALPGDKNA
DTKLPNGANYGFPVSTMHIVANKAWAEKNPAAAKLFAIMQLPVADINAQNAIMHDGKASEGDIQGHVDGWIKAHQQQFDG
WVNEALAAQK
>SEQF1516_EDU85697.1 IS66 family element, orf2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPS
ARDGKVFLTQAQLAMLLEGIDWRQPKRLLTSLTML
>SEQF1516_EDU85698.1 glutamate--cysteine ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGHPEALGSALTHKWITTDFAEALLEFITPVDGDIEHML
TFMRDLHRYTARNMGDERMWPLSMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW
QAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPFEKTECGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAKIGIDKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALL
RGGIEYIEVRSLDINPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLGIGCETAQF
PLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSARILRSMIDTGIGGTGKAFAEAYRNLLREEPL
EILREEDFVAEREASERRQQEMEAADTEPFAVWLEKHA
>SEQF1516_EDU85699.1 IS629 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU85700.1 hypothetical protein ECH7EC4501_5778 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFWLLLAICRKASSSFSGNTLPLEKFNMTGILLSFLIHIVNYIGNKNQHAAHDM
>SEQF1516_EDU85701.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFYKLCLLAVVILLLVMVMMDFTSRIMLVLTDGALVCGIVVLLWPVIKRNSLHNA
>SEQF1516_EDU85702.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGRTRHNVSEKEKPQTRRMQDVLRLAGELSIVRVLNDFQPLPILRVN
>SEQF1516_EDU85703.1 FAD dependent oxidoreductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYDFVIIGGGIIGMSTAMQLIDVYPDARIALLEKESGPACHQTGHNSGVIHAGVYYTPGSLKAQFCLAGNRATKAFCDQN
GIRYDNCGKMLVATSELEMERMRALWERTAANGIEREWLNADELREREPNITGLGGIFVPSSGIVSYREVTAAMAKIFQA
RGGEIIYNAEVSGLSEHKSGVVIRTRQGSDYEASTLISCSGLMADRLVKMLGLEPGFIICPFRGEYFRLAPEHNQIVNHL
IYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLAFKREGYRKRDFSFSDTLEILGSSGIRRVLQNHLRSGLGEMKNSLCKS
GYLRLVQKYCPRLSLSDLQPWPAGVRAQAVSPDGKLIDDFLFVTTPRTIHTCNAPSPAATSAIPIGAHIVSKVQTLLASQ
SNPGRTLRAARSVDALHAAFNQ
>SEQF1516_EDU85704.1 ATP-dependent chaperone ClpB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGGSVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGD
VQPSQDLVRVLNLCDKLAQKRGDNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQA
LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIINGEVPEGLKGRRVLAL
DMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILFIDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAIDLIDEAASS
IRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSDKERQYSELEEEWKAEKASLSGTQTIKAELE
QAKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLL
RMEQELHHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFDSDEAMVRIDMSEFMEK
HSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSDLIQERFGELDYAHMKELVLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDEAL
KLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAVQ
>SEQF1516_EDU85705.1 outer membrane assembly lipoprotein YfiO [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQDGNWRQAITQLEALDNRYPFGPYSQQVQLDLIYAYY
KNADLPLAQAAIDRFIRLNPTHPNIDYVMYMRGLTNMALDDSALQGFFGVDRSDRDPQHARAAFSDFSKLVRGYPNSQYT
TDATKRLVFLKDRLAKYEYSVAEYYTERGAWVAVVNRVEGMLRDYPDTQATRDALPLMENAYRQMQMNAQAEKVAKIIAA
NSSNT
>SEQF1516_EDU85706.1 antitermination protein Q [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLESVAKFHSPKSPMMSDSPRATASDSLSGTDVMAAMGMAQSQAGFGMAVFCGKHELSQNDKQKAINYLMQFAHKVSGK
YRGVAKLEGNTKAKVLQVLATFAYADYCRSAATPGARCRDCHGTGRAVDIAKTEQWGIVAEKECGRCKGVGYSRMPASAA
YRAVTMLIPNLTQPTWSRTVKPLYDALVVQCHKEESIADNILNAITR
>SEQF1516_EDU85707.1 succinate-semialdehyde dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPKMGADETRAAIDAANRALPVWRALTAKERANILRNWF
NLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPA
AMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGIPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQ
LMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQAVSKLHIGD
GLDKGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKAHERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDE
ADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCI
GL
>SEQF1516_EDU85708.1 major facilitator family transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKPNHELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLSASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIV
SMTLLAAGGMLITASSQSLAMMILGTALTGLFSVVAQILVPLAATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANL
GGWRTVFWVASVLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISNKILRTRALLGCLTFANFSILWTSMAFLLAA
PPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKSHHTTTFGLLLLLLSWLAIWFGHTSVLALIIGILVLDLTVQGVHI
TNQTVIYRIHPDARNRLTAGYMTSYFIGGAAGSLISASAWQHGGWAGVCLAGATIALVNLLVWWRGFHRQEAAN
>SEQF1516_EDU85709.1 lysozyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAKIRYGLSAAVLALIGAGASAPEILDQFLDEKEGNHTTAYRDGAGIWTICRGATRVDGKPVIPGMKLSKGKRTA
>SEQF1516_EDU85710.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTKIVKGKTTKQDVLASFGEPDSRSLIDGEEQWSYTMYNSQSKATSFIPVVGLLAGGADSQTKSLTVSFKGEKVSTYIF
NAGTSNVKTGIF
>SEQF1516_EDU85711.1 DNA-damage-inducible protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIEICIAKEKMTKMPNGAVDALKEELTRRISKRYDDVEVIVKATSNDGLSVTRTADKDSAKTFVQETLKDTWKSADEWF
VH
>SEQF1516_EDU85712.1 glycine betaine/L-proline ABC transporter, ATP binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIKLEIKNLYKIFGEHPQRAFKYIEQGLSKEQILEKTGLSLGVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEP
TRGQVLIDGVDIAKISDAELREVRRKKIAMVFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHS
YPNELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQN
GEVVQVGTPDEIINNPANDYVRTFFRGVDISQVFSAKDIARRTPNGLIRKTPGFGPRSALKLLQDEDREYGYVIERGNKF
VGAVSIDSLKTALTQQQGLDAALIDAPLAVDAQTPLSELLSHVGQAPCAVPVVDEDQQYVGIISKGMLLRALDREGVNNG
>SEQF1516_EDU85713.1 ribosomal large subunit pseudouridine synthase D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQRVLVNGKLCDKPKEKVLGGEQVAINAEIEEEARFEPQ
DIPLDIVYEDEDIIVINKPRDLVVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVE
SLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHFRVHTRLRLRLETGRTHQIRVHM
AHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDRQALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHK
DEVDWL
>SEQF1516_EDU85714.1 IpgB2, probably secreted by the Mxi-Spa secretion machinery [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRQSTKDIDEWIKDERIVYPSRVINQVIDNYCFQKNAKISTEERQRVFFLVSQENQLTLDVKAAQSSINHVIMGSASFG
KKMDALCDGMSRDVKNRTSDTIANLLADKFYQKHIDSDIDIVKLRNDIPDYLMRAIQG
>SEQF1516_EDU85715.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYEVLLLGLLVGAANYCFRYLPLRLRVGNARPTKRGAVGILLDTIGIASICALLVVSTAPEVMHDTRRFVPTLVGFAVL
GASFYKTRSIIIPTLLSALAYGLAWKVMAII
>SEQF1516_EDU85716.1 bacteriophage Lambda NinG protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIYRRKCKCCNEWFIPKYQNQYWCNEICGTKIALERRSKEREKAEKAEKAAEKKRRREEQKQKDKLKIQKLALKPRSYW
IKQAQQAVHAFIRERDRDLPCISCGTLTSAQWDAGHYRTTAAAPQLRFDERNIHKQCVVCNQHKSGNLVPYRVELISRIG
QEAVEEIESNHNRYRWTVEECRAIKAEYQQKLKKLRNSRSEVA
>SEQF1516_EDU85717.1 transporter, branched chain amino acid exporter (LIV-E) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEGCKDSLPIVISYIPVAFAFGLNATRLGFSPLESVFFSCIIYAGASQFVITAMLAAGSSLWVAALTVMAMDVRHVLYGP
SLRSRIIQRLQKSKTALWAFGLTDEVFAAATAKLVRNNRRWSENWMIGIAFSSWSSWVFGTVIGAFSGSGLLQGYPAVEA
ALGFMLPALFMSFLLASFQRKQSLCVTAALVGALAGVTLFSIPVAILAGIVCGCLTALIQAFWQGAPDEL
>SEQF1516_EDU85718.1 DNA repair protein RecN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGLCLGGRAEADMVRTGAARADLCARFSLKDTPAALRWL
EENQLEDGHECLLRRVISSDGRSRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSLLQEMT
ARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLANSGQLLTTSQNALALMADGEDA
NLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQIVEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPE
TLPQYYQSLLEEQQQLDDQADSQETLALAVTKHHQQALETARALHQQRQHYAEELAQLITDSMHALSMPHGQFTIDVKFD
EHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARKMETPALIFDEVDVGISGPTAAVVGKLLRQL
GESTQVMCVTHLPQVAGCGHQHYFVSKETDGAMTETHMQSLNKKTRLQELARLLGGSEVTRNTLANAKELLAA
>SEQF1516_EDU85719.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALERQLNGGVDFLRSVNNYFQSVMAEHRENKTSNKILMEKINSCVFGTDSNHFSCPESFLTCPITLDTPANGVFMRNSQ
GAEICSLYDKDTLVQLVETGGAHPLSREPITESMIMRKDECHFDSKKESFVASDA
>SEQF1516_EDU85720.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEALSLFSLFASSFLSATLLPGNSEVVLVAMLLSGISHPWVLVLTATMGNSLGGLTNVILGRFCPLRKTSRWQEKATGW
LKRYGAVTLLLSWMPVVGDLLCLLAGWMRISWGPVIFFLCLGKALRYVAVAAATVQGMMWWH
>SEQF1516_EDU85721.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARMGRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPL
YLAGERHEHYGIPHGFSSRVALERYLNGLFGEAS
>SEQF1516_EDU85722.1 protein CsiD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNALTAVQNNAVDSDQDYSGFTLIPSAQSPRLLELTFTEQTTKQFLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQ
PLLLKTLLNRAEGALLINAVGVDDVKQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELH
NDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDHYFRHPMARRPMRFAAPPSKNVSKDVFHPVFDVDQQGRPV
MRYIDQFVQPKDFEEGVWLSELSDAIEISKGILSVPVPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATHH
YQTHQ
>SEQF1516_EDU85723.1 serine/threonine-protein phosphatase 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIYERIDGSKYRNIWVVGDLHGCYTNLMKKLETIGFDTKKDLLISVGDLVDRGTENVECLELITFPWFRAVRGNHEQMM
IDGLSERGNVNHWLLNGGGWFFNLDYDKEILAKALAHKADELPLIIELVSKGKKYVICHADYPCDKYEFGKPVDHQQVIW
NRERISNSQDGIVKEIKGADTFIFGHTPAVKPLKFANQMYIDTGAVFCGNLTLIQVQGEGA
>SEQF1516_EDU85724.1 carboxymuconolactone decarboxylase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTLRQPYYELSPAVYNALVQAKTALENSTLDTTLMELIYLRVSQINGCAFCLEMHSKALRKSGVPQHKLDALAGWRVSH
HFDERERAALAWAESVTDIARTHAEDEVYQPLLEHFSAAEISDLTFAIGLMNCFNRLAVSMRM
>SEQF1516_EDU85725.1 putative prophage tail fibre C-terminus superfamily [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQRLCGCGKHDDREHGELLTAQLRLGPADILESDENGIIPEQARVITQVVILDADKKQIQCVVRPLQILRADGTWENIGG
MK
>SEQF1516_EDU85726.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIHAFWVQTRD
>SEQF1516_EDU85727.1 3-deoxy-7-phosphoheptulonate synthase, Tyr-sensitive [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKDALNNVHITDEQVLMTPAQLKAAFPLSLQQEAQIADSRKTISDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKAL
AAEVSDSLYLVMRVYFEKPRTTVGWKGLINDPHMDGSFDVEAGLQIARKLLLELVNMGLPLATEALDPNSPQYLGDLFSW
SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQVALLQTQGNPDGHVILRGGKAP
NYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDYRRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEM
KYGVSVTDACISWEMTDALLREIHQDLNGQLTARVA
>SEQF1516_EDU85728.1 nrdI protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYILIVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIA
SGNRNFGEAYGRAGDVIARKCGVPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA
>SEQF1516_EDU85729.1 transposase InsI for insertion sequence element IS30B/C/D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRTFTAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLRDTGGIKPHERKRAVAHLTLSEREEIRAGLSAKMSIRAI
ATALNRSPSTISREVQRNRGRRYYKAVDANNRANRMAKRPKPCLLDQNLPLRKLVLEKLEMKWSPEQISGWLRRTKPRQK
TLRISPETIYKTLYFRSREALHHLNIQHLRRSHSLRHGRRHTRKGERGTINIVNGTPIHERSRNIDNRRSLGHWEGDLVS
GTKNSHIDSFF
>SEQF1516_EDU85730.1 tyrosine-specific transport protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNRTLGSVFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLWALMCYTALLLLEVYQHVPADTGLGTLAKRYLGRYGQ
WLTGFSMMFLMYALTAAYISGAGELLASSISDWTGISMSATAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVVM
LVLLLPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMDGNIRKLRWVFITGSAIPLVAYIFWQVATLGSI
DSTTFMGLLANHAGLNGLLQALREMVASPHVELAVHLFADLALATSFLGVALGLFDYLADLFQRSNTVGGRLQTGAITFL
PPLAFALFYPRGFVMALGYAGVALAVLALIIPSLLTWQSRKHNPQAGYRVKGGRPALVVVFLCGIAVIGVQFLIAAGLLP
EVG
>SEQF1516_EDU85731.1 ferritin-1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKPEMIEKLNEQMNLELYSSLLYQQMSAWCSYHTFEGAAAFLRRHAQEEMTHMQRLFDYLTDTGNLPRINTVESPFAEY
SSLDELFQETYKHEQLITQKINELAHAAMTNQDYPTFNFLQWYVSEQHEEEKLFKSIIDKLSLAGKSGEGLYFIDKELST
LDTQN
>SEQF1516_EDU85732.1 trimethylamine N-oxide reductase III, subunit TorZ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRWGAMNVEVKDGKIVSSTGALAKTIPNSLQSTAADQVH
TTARIQHPMVRKSYLDNPLQPAKGRGEDTYVQVSWEQALKLIHEQHERIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQR
YMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPLNTLKIAWSSTDEQGLEYFHQLK
KSGKPVIAIDPIRSETIEFFGYNATWIAPNMGTDVALMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKSDNTPKS
AAWTAEITGVPEAQIVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYSNGGNPTRV
GGVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQTYPNIKMIWWAGGGNFTHHQDTNRLIKAWQ
KPEMIVVSECYWTAAAKHADIVLPITTSFERNDLTMTGDYSNQHIVPMKQAVAPQFEARNDFDVFAELAELLKPGGKEIY
TEGKDEMAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYGDFRADPVKNALGTPSGKIEIYSKT
LEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLHSQLNYAQLRKKYAVADREPITIHTEDAARFGIANGDLV
RVWNKRGQILTGAVVTDGIKKGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTGNAPKLT
AFDQPAVQA
>SEQF1516_EDU85733.1 serine/threonine-protein phosphatase 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQPAPVYQRIAGHQWRHIWLSGDIHGCLEQLRRKLWHCRFDPWRDLLISVGDVIDRGPQSLRCLQLLEQHWVRAVRGNH
EQMAMDALASQQMSLWLMNGGDWFIALADNQQKQAKTALEKCQHLPFILEVHSRTGKHVIAHADYPDDVYEWQKDVDLHQ
VLWSRSRLSERQKGQGITGADHFWFGHTPLRHRVDIGNLHYIDTGAVFGGELTFVQLQ
>SEQF1516_EDU85734.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPDANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDDDA
NMETIIYEGYGPGGTAIMIECLSDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE
DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMRLIDMLEDCDDVQEVYHNGEISD
EVAATL
>SEQF1516_EDU85735.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTINHQKLRELAFALQRMATPQKLLAFRAMLSPSAVLALLDQLEHARTTAPAIRLTLHHEIADFCATLGAPGEPETPEA
MQQELLQRIDNVFDFFLNQ
>SEQF1516_EDU85736.1 flagellar protein FlhE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLVAWRYQLIGPTPAGLRVRLCSQSRCVELDGQSGTTVAFSGIAAAEPLRFIWEVPGGGRLIPSLKVQRNEVIVNYR
>SEQF1516_EDU85737.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIMANWQSIDELQDIASDLPRFTHALDELSRRLGLNITPLTADHISLRCHQNATAERWRRGFEQCGELLSENMINGRPIC
LFKLHEPVQVAHWQFSIVELPWPREKRYPHEGWEHIEIVLPGDPETLNARALALLSDEGLSLPGISVKTSSPKGEHERLP
NPTLAVTDGKTTIKFHPWSIEEIVASEQSA
>SEQF1516_EDU85738.1 chemotaxis protein MotB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVMWLISISSPKELIQIAEYFRTPLATAVTGGDRISNSE
SPIPGGGDDYTQSQGEVNKQPNIEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRPM
FRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRANASRRELMVGGLDSGKVLRVVG
MAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHENAESQNEPVSALEKPEVAPQVSVPTMPSAEPR
>SEQF1516_EDU85739.1 DNA polymerase III, theta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQPEHLRSWFRERLIAHRLASVNLSRLPYEPKLK
>SEQF1516_EDU85740.1 lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFRDPILARLGRIAGRLGKSSRRRALINLSLCFPERSEA
EREAIVDEMFATAPQAMAMMAELAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAM
FHNQGNPVFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSEFVDFFATYKATLPAIGRLMKVC
RARVVPLFPIYDGKTHRLTIQVRPPMDDLLEADDHTIARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIQPYKRKDLY
PIK
>SEQF1516_EDU85741.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVNSNGSNNRVAGRDFHEKNIQIERYDGSHTVNIAIPSNNDDDDRPLLKAQRKELNSLVAAIAEASNTEAFIIWQKVHA
EIGVAGIDDMTVNQYKTAESFLHAMLERCKDHDACKALVSLLLRNSEDCGLRQKLLRYCHINFGTGRLNDLTRSQLQSAL
SWLEQQSASSHIESSTLPEVRLRASELIRLYPKEIIFFICVGVLVGGVISRAFFNL
>SEQF1516_EDU85742.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILANDFLEYLLNTERDLAARVRDRYDMYLKSLPVPQLADGKIVIDGRYMIDSHEGNYRLYRIEGGTPSVIGIYQRPSSA
IVDVIADSIRITHRHADTEDTVLEIQRLATACRDTLNGMTK
>SEQF1516_EDU85743.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTISALKEIEMQFCQILRLCAVLMTKADKKVVIFFHNMISVRFLPNGKR
>SEQF1516_EDU85744.1 hypothetical protein ECH7EC4501_5303 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLWRHYNLLFYYLQKVKYKLQLLKIRMGIKRITAISLISEDPLAD
>SEQF1516_EDU85745.1 trimethylamine N-oxide reductase III, c-type cytochrome subunit TorY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRGKKRIGLLFLLIAVVVGGGGFLMAQKALHKTSDTAFCLSCHSMSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDY
LFAKLKASKDIYHEFVSGKIDSDDKFEAHRQEMAETVWKELKATDSATCRSCHSFDAMDIASQSESAQKMHNKAQKGGET
CIDCHKGIAHFPPEIKMDDNAAHELESQAATSVTNGAHIYPFKTSRIGELATVNPGTDLTVVDASGKQPIVLLQGYQMQG
SENTLYLAAGQRLALATLSEEGIKALTVNGEWQADEYGNQWRQASLQGALTDPALADRKLLWQYAEKLDDTYCAGCHAPI
AADHYTVNAWPSIAKGMGARTSMSENELDILTRYFQYNAKDITEKQ
>SEQF1516_EDU85746.1 aspartyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGIVQVFFDPDRADALKLASELRNEFCIQVTGTVRARDE
KNINRDMATGEIEVLASSLTIINRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI
ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRDEDLRADRQPEFTQIDVETSFMT
APQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAERRYGSDKPDLRNPMELTDVADLLRSVEFAVFAGPANDPKGRVAA
LCVPGGASLTRKQIDEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILDRTAAQDGDMIFFGADNKK
IVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHPFTSPKDMTAAELKAAPENAVANAYDMVING
YEVGGGSVRIHNGDMQQTVFGILGINEEEQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAA
ACLMTEAPSFANPAALAELSIQVVKKAENN
>SEQF1516_EDU85747.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADRKQHRAIAERRHIQTEINRRLSRASRVAQIMHINMLHERSHALSNIYSASVFSYLADDLHEFQQLIQQQNKLH
>SEQF1516_EDU85748.1 flagellar biosynthesis protein FlhA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNLAAMLRLPTNLKSTQWQILAGPILILLILSMMVLPLPAFILDLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLF
TTLLRLALNVASTRIILMEGHTGAAAAGKVVEAFGHFLVGGNFAIGIVVFVILVIINFMVITKGAGRIAEVGARFVLDGM
PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVINVVGGLLVGVLQHGMSMGHAAE
SYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQDVGEQMVNQLFSNPSVMLLSAAVLGLLGLVPGMPNLVFLLFTAGL
LGLAWWIRGREQKAPAEPKPVKMAENNAVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRKKFAQEMGF
LPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLPGEATVDPAFGLNAIWIESALKEQAQIQGYT
VVEASTVVATHLNHLISQHAAELFGRQEAQQLLDRVAQEMPKLTEDLVPGVVTLTTLHKVLQNLLDEKVPIRDMRTILET
LAEHAPIQSDPHELTAVVRVALGRAITQQWFPGKDEVHVIGLDTPLERLLLQALQGGGGLEPGLADRLLAQTQEALSRQE
MLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRHIRMTATIGGK
>SEQF1516_EDU85749.1 transcriptional regulator, rpiR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMLEKIQSQLEHLSKSERKVAEVILASPDNAIHSSIAALALEANVSEPTVNRFCRSMDTRGFPDFKLHLAQSLANGTPY
VNRNVNEDDSVESYTGKIFESAMATLDHVRHSLDKSAINRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVVYS
DDIVLQRMSCMNCSDGDVVVLISHTGRTKNLVELAQLARENDAMVIALTSAGTPLAREATLAITLDVPEDTDIYMPMVSR
LAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKESRFDKQLLNLSDDR
>SEQF1516_EDU85750.1 arginyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGMMAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGP
GFINIFLDPAFLAEHVQQALASDHLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
DWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQSGDEYFREMWRKLVDITMTQNQ
ITYDRLNVTLTHDDVMGESLYNPMLPGIVADLKAKGLAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIAC
AKYRYETLHADRVLYYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLADLLDEALER
ARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNMLAFEGNTAPYMQYAYTRVLSVFRKAEIDEEQ
LAAAPVIIREDREAQLAARLLQFEETLTVVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAK
TLKLGLDTLGIETVERM
>SEQF1516_EDU85751.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKNANNPYSKFRNGVERHVHHVATSASRSNSRYNLNETHATPDGHAVKQIGEHAWLIEKAGIVVHKCPRNPFTGNRIFA
LNCGDNHFGQDFTLYEALRTVDRLLRGQSFIKQADL
>SEQF1516_EDU85752.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANWLNQLQSLLGQSSSSTSSSADQGLGKLLVPGALGGLAGLLVANKSARKLLTKYGTNALLIGGGAVAGTVLWNKYKDK
IRAAHQDEPQFGSQSTPLDERTERLILALVFAAKSDGHIDAKERAAIDQQLREAGVEEQGRVLIEQAIEQPLDPQRLATG
VRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQDVREGIERDLEQQKRTLAE
>SEQF1516_EDU85753.1 phage major tail tube protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVPKHLRFFTLFVDGENEVGKVTSVTLPKLTRKTDSYRGGGMMGAVSIDLGLDDSALDASFVMGGAVRELFLKYGGTID
GTLLRFAGEYYTDDESDLYEVEMRGRVTEIDMGEAKQGEATSHTYAIKNTYYKLSVNDRPLWEIDLLNFIYRKDGKDIVP
DRIRSALGLG
>SEQF1516_EDU85754.1 transposase encoded within prophage CP-933T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKREIQRVYDENHQVYGVRKVWRQLLREGIR
VARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVSAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFSGCIV
GWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTERLKEAKLLASTGSTGDSYDNVFY
>SEQF1516_EDU85755.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFALVLFVCYLDGGCEDIVVDVYNTEQQCLYSMSDQRIRHGGCFPIEDFIDGFWRPAQEYGDF
>SEQF1516_EDU85756.1 zinc uptake ABC transporter, permease protein ZnuB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIELLFPGWLAGIMLACAAGPLGSFVVWRRMSYFGDTLAHASLLGVAFGLLLDVNPFYAVIAVTLLLAGGLVWLEKRPQL
AIDTLLGIMAHSALSLGLVVVSLMSNIRVDLMAYLFGDLLAVTPEDLISIAIGVVIVVAILFWQWRNLLSMTISPDLAFV
DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAVLVGMVAVTDGLTFSAFYDTPAG
PSVVLCAALLFIISMMKKQAS
>SEQF1516_EDU85757.1 chemotaxis protein MotA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLILLGYLVVLGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGSFIVGNNGKAIKGTLKALPLLFRRSKYTKAMYMDLLA
LLYRLMAKSRQMGMFSLERDIENPRESEIFASYPRIIADSVMLDFIVDYLRLIISGHMNTFEIEALMDEEIETHESEAEV
PANSLALVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYGFISPLASVLRQKSAETSKMMQC
VKVTLLSNLNGYAPPIAVEFGRKTLYSSERPSFIELEEHVRAVKNPQQQTTTEEA
>SEQF1516_EDU85758.1 IS1203 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAVRMVLESQGEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTTAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU85759.1 phage protein gpU [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMMIYGMFVFELRTLPHQQLQQNKSWRHVKNERVNRSASWQYIGAGDDRIVLSGVLYPEITGGEVSLSLLTTQAYTGRPW
PLIDGVGQIYGMYVLTGTNTTRSEFDRYGKAKKIEFSLTLERCDEDLRERLQSSSFSDMLSGFKDKVTSSLNSAASSVKG
LL
>SEQF1516_EDU85760.1 chemotaxis response regulator protein-glutamate methylesterase CheB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVV
MVSSLTGKGSEVTLRALELGAIDFVTKPQLGIREGMLAYSEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIA
IGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGERVLPGHAYIAPGDRHMELARSG
ANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAVGVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAIN
MGGVCEVVDLNQVSQQMLAKISAGQAIRI
>SEQF1516_EDU85761.1 copper resistance protein CopC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASTARSLRYALAILTTSLVTPSVWAHAHLTHQYPAANAQVTAAPQAITLNFSEGVETGFSGAKITGPKNENIKTLPAKR
NEQDQKRLIVPLADSLKPGTYTVDWHVVSVDGHKTKGHYTFSVK
>SEQF1516_EDU85762.1 chemotaxis protein methyltransferase CheR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLADHKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSG
EWQAFINSLTTNLTAFFREAHHFPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVL
EKARSGIYRHEELKNLTPQQLQRYFMRGTGPHEGLVRVRQELANYVDFASLNLLAKQYTVPGPFDAIFCRNVMIYFDQTT
QQEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLRGQTVYALSKD
>SEQF1516_EDU85763.1 caudovirales tail fibre assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVFNSNEASWHLVEDHRGKTVYDVASGDALFISELGPLPENVTWLSPDGECQKWNGTSWAKDAEAEKLFRVREAEETKN
SLMQVASEHIAPLQDAVDLDIATEEEASLLAAWKTYRVLLNRVDTTVAADVEWPVAPQ
>SEQF1516_EDU85764.1 Holliday junction DNA helicase RuvA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQEAIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNG
VGPKLALAILSGMSAQQFVNAVEREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAE
QEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL
>SEQF1516_EDU85765.1 putative serine acetlyltransferase of prophage CP-933T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIWRLLREKKQRNRNFLFWWRLANEMYINGNKLHKKAAKKLNSKIINKFGCEIGLGANIGKGLTIPHHAGIVVHFAVDA
GENLVLRQNTTIGQIDGDMPSSRVKIGSNVDIGANCCIIGLSRKIGDNVKIGAMSFINKDIPSNCTYITKKSGVVLYK
>SEQF1516_EDU85766.1 hydrolase, carbon-nitrogen family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFWKVAAAQYEPRKTSLTEQVAHHLEFVRAAARQQCQLLVFPSLSLLGCDYSRRALPAPPDLSLLDPLCYAATTWRMTI
IAGLPVEYNDRFIRGIAVFAPWRKTPGIYHQSHGACLGRRSRTITVVDEQPQGMDMDPTCSLFTTGQCLGEPDLLASARR
LQFFSHQYSIAVLMANARGNSALWDEHGRLIVRADRGSLLLVGQRSSQGWQGDIIPLR
>SEQF1516_EDU85767.1 phage tail sheath protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSETRFHGARVTESTDLVTAINDVDSSVIGIVATADDADAELFPLNKPTLLTRVNDVLGKCGTTGTLYRALKAIADQVST
KVIVVRVAEHKEEGGKTQDQLVIGGSESDGSYTGMYALLVAEQDESIGYRPRILAAPELDTEAVTKSLCVIAGKLRAFVY
ATCHGCNTMAEAITYRQKFNEREVMLLWPDFIAYNLKSGKNETFPAPAYACGLRAYIDHEQGWHKSLSNVPVKNVLGMSR
HVFWSLQAEDSDANSLNNKEITTIIRRNGFRFWGNRTPETNAYIFEVYTRTAQVLADSIAEAQFETIDSPLTPANVKDVI
SAIRAKLDSLVTAGKLIGAECWYDIEDNSTTNLRQGRVRIRYKYTPVPPLEDMELYQSFTDEFFGPAFAVLGGA
>SEQF1516_EDU85768.1 plasmid segregation protein ParM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKICIDDGSTNIKLAWTENGERRNAISPNSFKSEWSAPFGGTQPANYMLDGVRYGFDPVSDRFVQTTDTQYQYSDVNVIA
IHHALVKSGITPQEVDVVVTLPLSEYFDTNAQPDMANINRKKANVMRPVEYQNGEAFTIRNVRVMPESIPAGFKAPADMS
PFESLLIVDLGGTTLDVAKVQGQLAGISQVFCDPHVGVSLMADAVLSVMATNGMRTSHHIANTIIEHRHDEAWLRQHIHN
DAHYASLMAVIREKEETLKQRVIRALAVFSGYGRVMVVGGGAEIVATAIREACGVNATFIADGVPQFALVNGLYAMNKE
>SEQF1516_EDU85769.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKEYKTLINKAPERFYFRLSASGAHAERAARDSLTRAIRSLYDVAFYADDLDALNELSELICAAECGEHIEPYKLGNIA
>SEQF1516_EDU85770.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVKKVQLLVTFLSMFSFSAVAMPFKTIERESFNGVWPFNTDEVQLQCLDGNPYVMNFDDNKLYALTGLARIKGKTFGAL
PLDNNNPFWLDNDAAPGLKKSLGDVTKAAFDLCDK
>SEQF1516_EDU85771.1 Holliday junction DNA helicase RuvB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIFIKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMG
VNLRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARGTPRIANRLLRRVRDFAEVKHDG
TISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKFFGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMA
TTRAWNHFGITPPEMP
>SEQF1516_EDU85772.1 alpha,alpha-trehalose-phosphate synthase (UDP-forming) [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSGETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNQF
SNAVLWPAFHYRLDLVQFQRPAWDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPT
PEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTAWGKAFRTEVYPIGIEPKEIAKQAAGP
LPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLAYEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGR
INGKYGQLGWTPLYYLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAANELTSALI
VNPYDRDEVAVALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISDLKQIVPRSAESQQRDKVATFPKLV
>SEQF1516_EDU85773.1 YebG protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVEVKYVVIREGEEKMSFTSKKEADAYDKMLDTADLLDTWLTNSPVQMEDEQREALSLWLAEQKDVLSTILKTGKLPSP
QVVGAESEEEDASHAA
>SEQF1516_EDU85774.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNAVIGALKGAISEKETQPSGRELNISGGNNRIAGRDYNETKGR
>SEQF1516_EDU85775.1 dATP pyrophosphohydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIDNYVNGMSEGSQRRGSVKDKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVEEGETAPQAAMREVKEEV
TIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESWFCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQA
IEQFVINAA
>SEQF1516_EDU85776.1 isochorismatase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLELNAKTTALVVIDLQEGILPFAGGPHTADEVVNRAGKLAAKFRASGQPVFLVRVGWSADYAEALKQPVDAPSPAKVLP
ENWWQHPAALGATDSDIEIIKRQWGAFYGTDLELQLRRRGIDTIVLCGISTNIGVESTARNAWELGFNLVIAEDACSAAS
AEQHNNSINHIYPRIARVRSVEEILNAL
>SEQF1516_EDU85777.1 putative methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIISMIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHH
DNCKIIAIDNSPAMIERCRRHIDAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGAL
VLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARLHKAGFEHSELWFQCFNFGSLVA
LKAEDAA
>SEQF1516_EDU85778.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTSVRIGAFEIDDGELHGESPGDRTLTIPCKSDPDLCMQLDAWDAETSIPALLNGEHSVLYRTRYDQQSDAWIMRLA
>SEQF1516_EDU85779.1 transposase InsI for insertion sequence element IS30B/C/D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDFINNVSVDSIGQRNSYVKTWGCGGLELWKNGTGFSEIANILGSKPGTIFTMLRDTGGIKPHERKRAVAHLTLSEREE
IRAGLSAKMSIRAIATALNRSPSTISREVQRNRGRRYYKAVDANNRANRMAKRPKPCLLDQNLPLRKLVLEKLEMKWSPE
QISGWLRRTKPRQKTLRISPETIYKTLYFRSREALHHLNIQHLRRSHSLRHGRRHTRKGERGTINIVNGTPIHERSRNID
NRRSLGHWEGDLVSGTKNSHIATLVDRKSRYTIILRLRGKDSVSVNQALTDKFLSLPSELRKSLTWDRGMELARHLEFTV
STGVKVYFCDPQSPWQRGTNENTNGLIRQYFPKKTCLAQYTQHEDLVAAQLNNRPRKTLKFKTPKEIIERGVALTD
>SEQF1516_EDU85780.1 integrase for prophage CP-933T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVRKIPSGKWLCECYPYGASGKRIRKQFATKSEALSYERRLMNSRVGDEFQDGSGPRLSELIARWFEMYGKTLSSGAER
KVKLEAICSRLGDPFASQFDKNMFATYRERRLSGEWNPKGKKKLSEATVNREQSYLHAVFAELKRLGEWSGENPLTGIRK
FREEEKELAFLYVDEIERLLIACDESRNKDLGVVVRIGLATGARWSEAEGLKQSQVLPGRITFVKTKGKKNRTVPISPQL
QAMLPKKRGALFSPCYEAFDAAIKRAKIELPDGQLTHVLRHTFASHFMMRGGNILVLQKILGHSDIKMTMRYAHFAPGHL
EAAVELNPFDNRG
>SEQF1516_EDU85781.1 oligopeptidase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPKAARIPHAMTLHGDTRIDNYYWLRDDTRSQPEVLDYLQQENSYGHRVMASQQALQDRILKEIIDRIPQREVSAPYIK
NGYRYRHIYEPGCEYAIYQRQSAFSEEWDEWEILLDANKRAAHSEFYSMGGMAITPDNTIMALAEDFLSRRQYGIRFRNL
ETGNWYPELLDNVEPSFVWANDSWTFYYVRKHPVTLLPYQVWRHAIGTPASQDKLIYEEKDDTYYVSLHKTTSKHYVVIH
LASATTSEVRLLDAEMADAEPFVFLPRRKDHEYSLDHYQHRFYLRSNRHGKNFGLYRTRMRDEQQWEELIPPRENIMLEG
FTLFTDWLVVEERQRGLTSLRQINRKTREVIGIAFDDPAYVTWIAYNPEPETARLRYGYSSMTTPDTLFELDMDTGERRV
LKQTEVPGFDAANYRSEHLWIVARDGVEVPVSLVYHRNHFRKGHNPLLVYGYGSYGASIDADFSFSRLSLLDRGFVYAIV
HVRGGGELGQQWYEDGKFLKKKNTFNDYLDACDALLKLGYGSPSLCYAMGGSAGGMLMGVAINQRPELFHGVIAQVPFVD
VVTTMLDESIPLTTGEFEEWGNPQDLQYYEYMKSYSPYDNVTAQAYPHLLVTTGLHDSQVQYWEPAKWVAKLRELKTDNH
LLLLCTDMDSGHGGKSGRFKSYEGVAMEYAFLVALAQGTLPARPAD
>SEQF1516_EDU85782.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNINYPAEYEIGDKVFTCIGAALFGQISAASNCWSNHVGIIIGHNGEDFLVAESRVPLSTITTLSRFIKRSSNQRYAIKR
LDAGLTEQQKQRIVEQVPSRLRKLYHTGFKYESSRQFCSKFVFDIYKEALCIPVGEIETFGELLNSNPNAKLTFWKFWFL
GSIPWERKTVTPASLWHHPGLVLIHAEGVETPQPELTEAV
>SEQF1516_EDU85783.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKEHAQGVFIRFIDFRGELLLRASAIDGIVPSEKNAATYVYLNGTRLTVELPYQTVREIISEAEKARQVNGDEPYIEII
CMDSEAEIQKAD
>SEQF1516_EDU85784.1 hypothetical protein ECH7EC4501_5304 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSEHIAWRYVFERLAIVIEHTFQDFAQFHRGTPTICYTGVIVFALII
>SEQF1516_EDU85785.1 chemotaxis response regulator CheY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSA
LPVLMVTAEAKKENIIAAAQAGASGYVVKPFTAATLEEKLNKIFEKLGM
>SEQF1516_EDU85786.1 phage tail protein, P2 GpE family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADIAVIFNWSPAEIFMMTPGEVVSWRERAALRSGNADNEDS
>SEQF1516_EDU85787.1 hypothetical protein ECH7EC4501_5300 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVPATIKTLPRVLFFTLSSVLTIFMSDICGAG
>SEQF1516_EDU85788.1 phosphoribosylglycinamide formyltransferase 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIV
PEIEAIATDMLIQLEEEGLNVVPCARATKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVAAIGYPCIVKPVMSS
SGKGQTFIRSAEQLAQAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFCAPVGHRQEDGDYCESWQPQQMS
PLALERAQEIARKVVLALGGYGLFGVELFVCGDEVIFSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGP
AASAVILPQLTSQNVTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
>SEQF1516_EDU85789.1 universal stress protein C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPEMYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPV
DKTFIAYGELSEHILEVCRKYHFDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD
>SEQF1516_EDU85790.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAKEKNIINTLKIVSAEQDKLSRAAQKDNQHMAALYALTIAIATPEAAKVIEEQSKEIDTLKTQSTVAAMNPSSIGRCI
YILGSAMMLQYTIIAELHGKYLITPYHTKESELLTNLRLIERSQAVFIDDAQRAVFNA
>SEQF1516_EDU85791.1 flagellar transcriptional activator FlhC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLYKELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAW
QFLLKTGLCNGVDAVIKAYRLYLEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC
QPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV
>SEQF1516_EDU85792.1 phosphogluconate dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPQLLRVTNRIIERSRETRSAYLARIEQAKTSTVHRSQLACGNLAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSA
HQPYEHYPEIIRKALHEANAVGQVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPG
LTMAALSFGHLPAVFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAPGTCTFYGTANTNQMVVEFMGMQ
LPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWMPIGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGIQINW
DDFSDLSDVVPLMARLYPNGPADINHFQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGELDWREGAEK
SLDSNVIASFEQPFSHHGGTKVLSGNLGRAVMKTSAVPVENQVIEAPAVVFESQHDVMPAFEAGLLDRDCVVVVRHQGPK
ANGMPELHKLMPPLGVLLDRCFKIALVTDGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEA
ELAAREPHIPDLSASRVGTGRELFSALREKLSGAEQGATCITF
>SEQF1516_EDU85793.1 L-arabinose ABC transporter, periplasmic L-arabinose-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHKFTKALAAIGLAAVMSQSAMAENLKLGFLVKQPEEPWFQTEWKFADKAGKDLGFEVIKIAVPDGEKTLNAIDSLAASG
AKGFVICTPDPKLGSAIVAKARGYDMKVIAVDDQFVNAKGKPMDTVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAV
MAITSNELDTARRRTTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPEVKHWLIVGMNDSTVLGGVRATE
GQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLLPSPDVHGYKSSEMLYNWVAKGVEPTKFTEVTDVVLITRDNFKEE
LEKKGLGGK
>SEQF1516_EDU85794.1 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNWKTSAESILTTGPVVPVIVVKKLEHAVPMAKALVAGGVRVLEVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQL
AEVTEAGAQFAISPGLTEPLLKAATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGVKALQAIAGPFSQVRFCP
TGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKL
>SEQF1516_EDU85795.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTILDYIATHPGCSGGEIAAALNTPTTAINAELRRLWRGGLVIRTNRSTGGRARKTGGQASYHVNPMPFGCSNPLTHMFN
QLLKEARA
>SEQF1516_EDU85796.1 flagellar transcriptional activator FlhD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMATTLAALTLPQMVKLAETNQLVCHFRFDSHQTITLLTQ
DSRVDDLQQIHTGIMLSTRLLNDVNQPEEALRKKRA
>SEQF1516_EDU85797.1 putative methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSNAVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIE
TLMRNLMPWRKGPFSLYGVNIDTEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQ
FEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVNEGELVLETLVIDGDENTVLVPG
DRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVSVTTTEEQRRTEWMVTESLSDFLDPHDPSKTVEGYPAPKRAVLIA
RKP
>SEQF1516_EDU85798.1 flagellar biosynthetic protein FlhB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDESDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVSVIWFGGVSLARRLSGMLSAGLHFDHSIIKDPNLILGQ
IILLIREAMLALLPLISGVVLVALISPVMLGGLVFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAILKTILVGSVTG
FFLWHHWPHMMRLMAESPITAMGNAMDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKKLRMSRQDIRDEFKQSEGDPHVK
GRIRQMQRAAARRRMMADVPKADVIVNNPTHYSVALQYDENKMSAPKVVAKGAGLVALRIREIGAENNVPTLEAPPLARA
LYRHVEIGQQIPGQLYAAVAEVLAWVWQLKRWRLAGGQRPVQPTHLPVPEALDFINEKPTHE
>SEQF1516_EDU85799.1 putative inner membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSALYAVLSALLLMKFSFDVVRLRMQYRVAYGDGGFSELQSAIRIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIV
LLAGRLMHYYGFHHRLFRWRRSGMSATWCALLLMVLANLWYMPWELVFSLR
>SEQF1516_EDU85800.1 phage tail protein E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKETKNIDTENTVVTDTVKETSERGVKLTQPIERGGEKITYVEITGAIEQAGSLRDLSLSDVLNLKAESMFTLLSRVTSP
RLDEVTIKKMASRDFIQLCVVAVNFLSGADSGGKNEQATEA
>SEQF1516_EDU85801.1 high-affinity zinc uptake ABC transporter, ATP-binding protein ZnuC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDT
TLPLTVNRFLRLRPGTHKEDILPALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY
DLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFGPRGAEQLGIYRHHHNHRHDLQG
RIVLRRGNDRS
>SEQF1516_EDU85802.1 hypothetical protein ECH7EC4501_5269 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTSFTHSFSPLYPLNDSATIITHHARNLTPAPFSRHGDNKKQ
>SEQF1516_EDU85803.1 trehalose-phosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEPLTETPELSAKYAWFFDLDGTLAEIKPHPDQVVVPDNILQGLQLLATASDGALALISGRSMVELDALAKPYRFPLAG
VHGAERRDINGKTHIVHLPDAIARDINVQLHTVIAQYPGAELETKGMAFALHYRQAPQHEDALMTLAQRITQIWPQMALQ
QGKCVVEIKPRGTSKGEAIAAFMQEAPFIGRTPVFLGDDLTDESGFAVVNRLGGMSVKIGTGATQASWRLAGVPDVWSWL
EMITTALQQKRENNRSDDYESFSRSI
>SEQF1516_EDU85804.1 pyruvate kinase II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVST
FKEGKVFLNIGDKFLLDANLGKGEGDKEKVGINYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK
GINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDAKIVAKVERAEAVCSQDAMDDII
LASDVVMVARGDLGVEIGDPELVGIQKALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAE
TAAGQYPSETVAAMARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTALMTSRISS
GLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGYLMSGDLVIVTQGDVMSTVGSTNTTRILTVE
>SEQF1516_EDU85805.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKFLVLTLGIISCQVYAEDTLIVNDHDISAIKDCWQKNSGDDTDINVIKSCLRQEYNLVDAQLNKAYGEAYRYIEQVPR
TGAKKPDTEQLNLLKKSQRAWLDFRDKECELILSNEDVQDLSNPYSESEWLSCMIIQTNTRTRQLQLYRNSEDFYPSPLT
RG
>SEQF1516_EDU85806.1 GAF domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKTEFYADLNRDFNALMAGETSFLATLANTSALLYERLTDVNWAGFYLLEDDTLVLGPFQGKIACVRIPVGRGVCGTAV
ARNQVQRIEDVHAFDGHIACDAASNSEIVLPLVVKNQIIGVLDIDSTVFGRFTDEDEQGLRQLVAQLEKVLATTDYKKFF
ASVAG
>SEQF1516_EDU85807.1 SEC-C domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTGPLNESELEWLDDILTKYNTDHAILDVAELDGLLTAVLSSPQEIEPAQWLVAVWGGADYVPRWASEKEMTRFMNLAF
QHMADTAERLNEFPEQFEPLFGLREVDGSELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFERVEKMS
PEAFEESVDAIRLAALDLHAYWMAHPQEKAVQQPIKAEEKPGRNDPCPCGSGKKFKQCCLH
>SEQF1516_EDU85808.1 L-arabinose ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGAGKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAAL
NAGVAIIYQELHLVPEMTVAENIYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALAR
NAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKDGRYVKTFTDMQQVDHDALVQAM
VGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPISLAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPI
DIRKPSHAIAAGMMLCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPGAEQLIMNL
SGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHEIYNVIYALAAQGVAVLFASSDLPEVLGVADRIVVMREGEIAGE
LLHEQADERQALSLAMPKVSQAVA
>SEQF1516_EDU85809.1 integral membrane protein, PqiA family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRAIGEELPRGDYQRCPQCDMLFSLPEINSHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLMPFAWGEPLLHIWLLG
IRIDANVMQGIWQMTKQGDAITGSMVFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLKEWVMLDIYLVGIGVA
SIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFYPQRPATRRDEKLRVCLGCHFTGYPDQRGRCPRCHIPL
RLRRRHSLQKCWAALLASIVLLLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIASILVPFTKVIVMFTL
LLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAAFYFGAAVILTILAVEWLDSRLLW
DAHESGNARFDD
>SEQF1516_EDU85810.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKNMKKRGAFLGLLLVSACASVFAANNETSKSVTFPKCEGLDAAGIAASVKRDYQQNRVARWADDQKIVGQADPVAWVS
LQDIQGKDDKWSVPLTVRGKSADIHYQVSVDCKAGMAEYQRR
>SEQF1516_EDU85811.1 methyl-accepting chemotaxis protein II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSN
QQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNA
MGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLTPLAKIIAHIREIAGGNLANTLT
IDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADN
ARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGE
VRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVDAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDH
VTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLAASPLTNKPQTPSRPASEQPPAQPRLRIAEQDPNWETF
>SEQF1516_EDU85812.1 copper resistance protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAFTWIALRFIHFTSLMLVFGFAMYGAWLAPLTIRRLLTKRFLRLQQHAAVWSLISATAMLAVQGGLMGTGWKDVFSPN
IWQAVLQTQFGGVWLWQIVLALVTLIVALMQPRNMPRLLFMLTTAQFILLAGVGHATLNEGVTAKIHQTNHAIHLICAAA
WFGGLLPVLWCMQLIKGRWRHQAIQALMRFSWCGHFAVIGVLASGVLNALLITGFPPTLTTYWGQLLLLKAILVMIMVVI
ALANRYVLVPRMRQDEDRAAPWFVWMTKLEWAIGAVVLLIISLLATLEPF
>SEQF1516_EDU85813.1 exodeoxyribonuclease X [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVHPDRPISPQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAH
NASFDRRVLPEMPGEWICTMKLARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLENT
>SEQF1516_EDU85814.1 ribosomal RNA small subunit methyltransferase F [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVNTLKTSVADFLRLTAPYGWTLTPIPWCEEGFWIERDD
EDALPLGSTAEHLSGLFYIQEASSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHA
NISRCGISNVALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESNQEIAATQRELIDSAFHALRSGG
TLVYSTCTLNREENESVCLWLKETYPDAVEFLPLGDLFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPTP
KYKVGNFPFSPVKDREAAQIRQAAASVGLNWDGNLRLWQRDKEVWLFPVGIEALIGKVRFSRLGIKLAETHNKGYRWQHE
AVIALASPDNENAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPIGLAKRIGSRLKNSYPRELVRDGKLFTSNA
>SEQF1516_EDU85815.1 copper homeostasis protein CutC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLKSVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVR
TVRELGFPGLVTGVLDVDGNVDMSRMEKIMAAAGPLAVTFHRAFDMCANPLNTLNNLAELGIARVLTSGQKSDALQGLSK
IMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSSDAHADEYSRYVVDGAAVAEMKG
IIERHQAK
>SEQF1516_EDU85816.1 metalloprotease, opacity-associated protein A family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQQIARSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHRDATPIVKTIELEQNEIRSLLPEASEPIDQAAQEDEAI
PQDELDDKIAGEAGVHEYVVSTGDTLSSILNQYGIDMGDITQLAAADKELRNLKIGQQLSWTLTADGELQRLTWEVSRRE
TRTYDRTAANGFKMTSEMQQGEWVNNLLKGTVGGSFVASARNAGLTSAEVSAVIKAMQWQMDFRKLKKGDEFAVLMSREM
LDGKREQSQLLGVRLRSEGKDYYAIRAEDGKFYDRNGTGLAKGFLRFPTAKQFRISSNFNPRRTNPVTGRVAPHRGVDFA
MPQGTPVLSVGDGEVVVAKRSGAAGYYVAIRHGRSYTTRYMHLRKILVKPGQKVKRGDRIALSGNTGRSTGPHLHYEVWI
NQQAVNPLTAKLPRTEGLTGSDRREFLAQAKEIVPQLRFD
>SEQF1516_EDU85817.1 chemotaxis adaptor protein CheW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQVTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDV
DYNDNTVVIVLNLGQRVVGIVVDGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
SAASEVA
>SEQF1516_EDU85818.1 crossover junction endodeoxyribonuclease RuvC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSRLKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALK
LGQARGVAIVAAVNQELPVFEYAARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM
SESRLNLARGRLR
>SEQF1516_EDU85819.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDSIHGHEVLNMMIESGEQYTHASLEAAIKARFGEQARFHTCSAEGMTAGELVAFLAAKGKFIPSEEGFSTDQSKICRH
>SEQF1516_EDU85820.1 chemotaxis phosphatase CheZ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEAAEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQ
DQMEKSAKALTQRWDDWFADPIDLADARELVTDTRKFLADVPAHTSFTNAQLLEIMMAQDFQDLTGQVIKRMMDVIQEIE
RQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKAGVVASQDQVDDLLDSLGF
>SEQF1516_EDU85821.1 ProP effector [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVDRVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATR
VDLDGNPCGELDEQHVEHARKQLEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPTTPRRKEGAERKPRAQK
PVEKAPKTAKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLNSGMSLIVRAEHLVF
>SEQF1516_EDU85822.1 putative regulator for prophage CP-933T [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGITININVNAPYVSLQKYAEITGIPLNTCKKMLADGRIIIRPKRAKMEKPEVNLVAMLKDALANS
>SEQF1516_EDU85823.1 putative tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDTTMQLLSQGTDHVKVPDFDILAEGKTLSGVAERLMSLSLTDNRGFEADQLTITLDDADGQLQLPPRGARLTVLIGWK
GEPLTEKGTCRFNLSMQHPFQLSLSVF
>SEQF1516_EDU85824.1 ferritin family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATAGMLLKLNSQMNREFYASNLYLHLSNWCSEQSLNGTATFLRAQAQSNVTQMMRMFNFMKSVGATPIVKAIDVPGEKL
NSLEELFQKTMEEYEQRSSTLAQLADEAKELNDDSTVNFLRDLEKEQQHDGLLLQTILDEVRSAKLAGMCPVQTDQHVLN
VVSHQLH
>SEQF1516_EDU85825.1 phage replication protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAEYIRDWQQPRHAVGREGTGIPAPESALSSWLDAYRVENERRQEMADAAFSATPLGNLINKSLDAQEKQDKTITLAGD
ARKQARGAVDEAMASLRLLPSYLRDPLIRHLSFLRKKQEADRQKGKKSWQAERYARGNLRKIFERLERTDHRWLTQGYRS
LAGRERLDDLLYLPQLNKHQIQTLATMTAAMFSSTFEKLCDGFGATDGELTMDVTLKAYQMLARMALHLHAMPPHYDALT
TDKDRRNEPDTELLPGAILRLTCAEWWKRKLWLLRCEWREEQLRAACLVSRKTSPYLSQDALSEFRAQREKTRDFLKSFM
LENEDGFTIDLETVYYAGVSNPVHRKAEMMATMKGLELLAEARGDKAVFLTVTCPSKYHATTENGHPNPKWNGATMRDSS
DYLVNTFFAAVRKKLNRDGLRWYGIRTVEPHHDGTVHWHMMVFAHPEEIDTIVSHTRDIAIQEDRHELGDDITPRFKAEY
VDGSKGTPTSYIATYIGKNLDSRAVDGIDPKTGKPRVDHETGKSMTESVERAIGWARLHRVRQFQFFGIPSRQVWRELRR
LASQMARNPEGPQRLKDDAMDAVLAAADAGCFTTYIEKQGGVLVPRKDYLIRTAYDLADELNDYGEQSVQIYGIWSPLIG
ESSRVCTHPDNWKLVRRKPGVEDSARENGFDLQGGPAAPWTRGNNCPRVQETDNNGTEQPEERPAPWPQLPDGVDVNEWM
RSLKRHERRALMRSLRDKQAKNSSDEMQSWTQSRKQQRPLPDNHELLAKEWRESAESLGLHIGEQQMQHLLRGGSLYVDG
SIIAPQGFEIVRKPDTRPDSRITQLWQRLSRNHGVSSTEIRHNPVASYLAQLGASDPEAAARLASTLQQDQNTMKTPVTV
LSDMLRAIRDAEHAQRISETTERASRKADLLRGGLTSGNKKQTETGLTNPVNEQKTRRDI
>SEQF1516_EDU85826.1 C-terminal processing peptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATVSERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSH
NVLLASDVEQFAKKKTELGDELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEAEL
NALWDSKVKFDELSLKLAGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAFAREIDPHTNYLSPRNTEQFNTEMS
LSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPA
GKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDLRSNGGGALTE
AVSLSGLFIPAGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFSASASEIFAAAMQDYGRALVVGEPTFGKGTVQQ
YRSLNRIYDQMLRPEWPALGSVQYTIQKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSG
DLTAFEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRLARLNERFKREGKPELKKL
DDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK
>SEQF1516_EDU85827.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQTLNADQELVSDVVACQLVIKQILDVLDVIAPVEVREKMSSQLKNIDFTHHPAAADPVTMRAIQKAIALIELKFTPQG
ESH
>SEQF1516_EDU85828.1 mce-related protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHMSQETPASTTEAQIKNKRRISPFWLLPFIALMIAGWLIWDSYQDRGNTVTIDFMSADGIVPGRTPVRYQGVEVGTVQD
ISLSDDLRKIEVKVSIKSDMKDALREETQFWLVTPKASLAGVSGLDALVGGNYIGMMPGKGKEQDHFVALDTQPKYRLDN
GDLMIHLQAPDLGSLNSGSLVYFRKIPVGKVYDYAINPNKQGVVIDVLIERRFTDLVKKGSRFWNVSGVDANVSISGAKV
KLESLAALVNGAIAFDSPEESKPAEAEDTFGLYEDLAHSQRGVIIKLELPSGAGLTADSTPLMYQGLEVGQLTKLDLNPG
GKVTGEMTVDPSVVTLLRENTRIELRNPKLSLSDANLSALLTGKTFELVPGDGEPRKEFVVVPGEKALLHEPDVLTLTLT
APESYGIDAGQPLILHGVQVGQVIDRKLTSKGVTFTVAIEPQHRELVKGDSKFVVNSRVDVKVGLDGVEFLGASASEWIN
GGIRILPGDKGEMKASYPLYANLEKALENSLSDLPTTTVSLSAETLPDVQAGSVVLYRKFEVGEVITVRPRANAFDIDLH
IKPEYRNLLTNNSVFWAEGGAKVQLNGSGLTVQASPLSRALKGAISFDNLSGASASQRKGDKRILYASETAARAVGGQIT
LHAFDAGKLAVGMPIRYLGIDIGQIQTLDLITARNEVQAKAVLYPEYVQTFARGGTRFSVVTPQISAAGVEHLDTILQPY
INVEPGRGNPRRDFELQEATITDSRYLDGLSIIVEAPEACSLGIGTPVLFRGLEVGTVTGMTLGTLSDRVMIAMRISKRY
QHLVRNNSVFWLASGYSLDFGLTGGVVKTGTFNQFIRGGIAFATPPGTPLAPKAQEGKHFLLQESEPKEWREWGTALPK
>SEQF1516_EDU85829.1 chemotaxis protein CheA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIFRAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQ
LNTDIINLFLETKDIMQEQLDAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQLPRRI
ILSRLKASEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEADQITFETVEVSPKISTPPVLKLAA
EQAPTGRVEREKTTRSSESTSIRVAVEKVDQLINLVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVM
SIRMMPMEYVFSRYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKRLAAGKNSVGN
LILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNI
QEMGGHVEIQSKQGTGTTIRILLPLTLAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIV
ELWKVFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQA
INREQRMANTAA
>SEQF1516_EDU85830.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIYIGLPQWSHPKWVRLGITSLEEYARHFNCVEGNTTLYALPKPEVVLRWREQTTDDFRFCFKFPATISHQAALRHCDDL
VTEFLTRMSPLAPRIGQYWLQLPATFGPRELPALWHFLDSLPGEFNYGVEVRHPQFFAKGEEEQTLNRGLHQRGVNQVIL
DSRPVHAARPHSEAIRDAQRKKPKVPVHAVLTATNPLIRFIGSDDMTQNRELFQVWLQKLAQWHQTTTPYLFLHTPDIAQ
APELVHTLWEDLRKTLPEIGAVPAIPQQSSLF
>SEQF1516_EDU85831.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIKHFPVVRFTSRGREYEVDERLITTIDKHRSEKDAHHIYLTDGTYFCATNVARVNLIRQVQEPRR
>SEQF1516_EDU85832.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKKSILAFLLLTSSAAALAAPQVITVSRFEVGKDKWAFNREEVMLTCRPGNALYVINPSTLVQYPLNDVAQKEVASGKT
KAQPISVIQIDDPNNPGEKMSLAPFIERAEKLC
>SEQF1516_EDU85833.1 hypothetical protein ECH7EC4501_5289 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIFISWLVLIISVACAIGIMRIIHSVKKIERFFTDK
>SEQF1516_EDU85834.1 methyl-accepting chemotaxis protein IV [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFNRIRISTTLFLILILCGILQIGSNGMSFWAFRDDLQRLNQVEQSNQQRAALAQTRAVMLQASTTLNKAGTLTALSYPA
DDIKTLMTTARASLTQSTTLFKSFMAMTAGNEHVRALQKETEKSFARWHNDLEHQATWLESNQLSDFLTAPVQGSQNAFD
VNFEAWQLEIIHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPLAIIGSHFDSIAAGNLARPIAVY
GRNEITAIFASLKTMQQALRGTVSDVRKGSQEMHIGIAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNAR
QASELAKNAATTAQAGGVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVR
NLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMTDIVSSVTRVNDIMGEIASASEEQRRGIEQVAQAVSQMDQVT
QQNASLVEEAAVATEQLANQADHLSSRVAVFTLEEHEVARHESAQLQIAPVVS
>SEQF1516_EDU85835.1 zinc ABC transporter, periplasmic zinc-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIGRIMLHKKTLLFAALFAALWGGATQAADAAVVASLKPVGFIASAIADGVTETEVLLPDGASEHDYSLRPSDVKRLQNA
DLVVWVGPEMEAFMQKPVSKLPEAKQVTIAQLEDVKPLLMKSINGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATA
VAIHGKLVELMPQSRAKLDANLKDFEAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFGLTPLGHFTVNPEIQPGA
QRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMGTLDPLGTNIKLGKTSYSEFLSQLANQYASCLKGD
>SEQF1516_EDU85836.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLSFITRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIPSSLFKNGAGVWGGETLLPGMSPLAQVYSGHQFGVWA
GQLGDGRGILLGEQLLADGTTMDWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRE
TVEPGAMLMRVAPSHLRFGHFEHFYYRREPDKVRQLADFAIRHYWSHLEDDEDKYRLWFNDVVARTASLIAQWQTVGFAH
GVMNTDNMSLLGLTLDYGPFGFLNDYEPGFICNHSDHQGRYSFDNQPAVALWILQRLAQTLSPFVAVDALNEALDSYQQV
LLTHYGQRMRQKLGFMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDWFARYRGRL
QQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEALRNPFSDRDDDYVSRPPDWGKRLEVSCSS
>SEQF1516_EDU85837.1 ankyrin repeat protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQNDIIIRTHYKSPHRMHIDSDIPTPSSEPINQFAPQLITLLDTSDLSSMLSYCVTQEFTANCRKISQNCYSTALFTIN
FATSPIHAENIFITLHYKKEIISLLLETTPIKANHLRSILDYIEQEQLTAENRNHCMKLSKKIHREKTIQPTVNLNGSAF
FSQSPSDAIFCRHLSLQYALDSLRNGKGKVNLIKHYSSVESIQQHVPLVRDAEFRALLRHPPAGSRVIASKDFGFALDIF
FCRMMANNVSHMSAILYIDNHTLSVRLRIKQSAYGQLNYVVSVYDPNDTNVAVRGTHRTARGFLSLDKFISSGPDAQTWA
DRYVRNCAIAILPLLPEGVPGAIFTGIATRMPFAPIHPSAMLLIMATGQTQQLITLFRQLPILPEKEIIEIITAQNSIGT
PALFLAMMNGHTDNVKIFMQEIQSLVDNHIIHEDNLVKLLQTKSANETPGLYISMLYGFDEIIDIFLNALTTPIAQELLN
KKLVMSILAMKIHDGEPGLYAAMENNHPLCVTRFLSKINGIAFKYKLSKANIMDLLKGATAQGTPALYIAMSKGNEDVVL
SYISTLGAFAKKHSFSQHQLFTLLAAKNHDNMSAVHIAIHHNHYKTVETYYAAINVISQSMSFSADELKTYL
>SEQF1516_EDU85838.1 PTS system, N,N'-diacetylchitobiose-specific IIB component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLAGEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVID
SLLYGKVDGLGVLKAAVAAIKKAAAN
>SEQF1516_EDU85839.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIFLENLYHSDCYFLPIRDNQQVLVGVELITHFSSEDGTVRIPTSRVIAQLTEEQHWQLFSEQLELLKSCQHFFIQHKL
FAWLNLTPQVATLLLERDNYAGELLKYPFIELLINENYPHLNEGKDNRGLLSLSQVYPLVLGNLGAGNSTMKAVFDGLFT
RVMLDKSFIQQQITHRSFEPFIRAIQAQISPCCNCIIAGGIDTPEILAQITPFDFHALQGCLWPAVPINQITTLVQR
>SEQF1516_EDU85840.1 L-asparaginase 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKKSIYVAYTGGTIGMQRSEQGYIPVSGHLQRQLALMPEFHRPEMPDFTIHEYTPLMDSSDMTPEDWQHIAEDIKAHYD
DYDGFVILHGTDTMAYTASALSFMLENLGKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPINEVTLFFNNRLYRGNR
TTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPHGEGELIVHPITPQPIGVVTIYPGISADVVRNFLRQPVKALILR
SYGVGNAPQNKAFLQELQEASDRGIVVVNLTQCMSGKVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQELDTE
TIRKAMSQNLRGELTPDD
>SEQF1516_EDU85841.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASGDLVRYVITVMLHEDTLTEINELNNYLTRDGFLLTMTDDEGNIHELGTNTFGLISTQSEEEIRELVSGLTQSATGKD
PEITITTWEEWNSNRK
>SEQF1516_EDU85842.1 IS1203 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTSETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU85843.1 hypothetical protein ECH7EC4501_4675 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKFTGNYCAILTQRAPKAGIFCAIVDIINNHRSNHLTTGGKQSEILLPSTHSLSE
>SEQF1516_EDU85844.1 FeS assembly ATPase SufC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSIKDLHVSVEDKAILRGLSLDVRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTGGTVEFKGKDLLALSPEDRAGEGI
FMAFQYPVEIPGVSNQFFLQTALNAVRSYRGQETLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
VLEPELCILDESDSGLDIDALKVVADGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHVLYQGRIVKSGDFTLVKQLEEQG
YGWLTEQQ
>SEQF1516_EDU85845.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIASIAANGEFSLFPGMERIVTLLEGGEMFLESADHFNHTLK
PLQPFAFAADQVVKAKLTAGQMSMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFD
GRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ
>SEQF1516_EDU85846.1 ribosomal protein L35 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHLRPKAMVSKGDLGLVIACLPYA
>SEQF1516_EDU85847.1 fructosamine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGHDFFVKCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVG
ADRDYSFLVMDYLPPRPLDAHSAFILGQQIARLHQWSDQPQFGLDFDNSLSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDRECDLAMLPLHTEQPPQIYDGYQ
SVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIAQQSLDRLLAA
>SEQF1516_EDU85848.1 NADP-specific glutamate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDQTYSLESFLNHVQKRDPNQTEFAQAVREVMTTLWPFLEQNPKYRQMSLLERLVEPERVIQFRVVWVDDRNQVQVNRAW
RVQFSSAIGPYKGGMRFHPSVNLSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGA
DTDVPAGDIGVGGREVGFMAGMMKKLSNNTACVFTGKGLSFGGSLIRPEATGYGLVYFTEAMLKRHGMGFEGMRVSVSGS
GNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTKEKLARLIEIKSSRDGRVADYAKEFGLVYLEGQQPWSVPVDIALP
CATQNELDVDAAHQLIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLGWKAEKVDA
RLHHIMLDIHHACVEHGGEGEQTNYVQGANIAGFVKVADAMLAQGVI
>SEQF1516_EDU85849.1 IS1203 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU85850.1 selenide, water dikinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLVGNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDF
GRIAATNAISDIFAMGGKPIMAIAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTE
RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFANIEGVKAMTDVTGFGLLGHLSEM
CQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTERNFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKAT
AAEFGIELTAIGELVPARGGRAMVEIR
>SEQF1516_EDU85851.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLDDIINSMTPEVYQRLSTAVELGKWPDGVALTEEQKENCLQLVMLWQARNNTEAQHMTIDTNGQMVMKSKQQLKEDFG
ISAKPIAMFK
>SEQF1516_EDU85852.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQNKAFSTPFILAVLCIYFSYFLHGISVITLAQNMSSLAEKFSTDNAGIAYLISGIGLGRLISILFFGVISDKFGRRAV
ILMAVIMYLLFFFGIPACPNLTLAYGLAVCVGIANSALDTGGYPALMECFPKASGSAVILVKAMVSFGQMFYPMLVSYML
LNNIWYGYGLIIPGILFVLITLMLLKSKFPSQLVDASVANELPQMNSKPLVWLEGVSSVLFGVAAFSTFYVIVVWMPKYA
MAFAGMSEAEALKTISYYSMGSLVCVFIFAALLKKMVRPIWANVFNSALATITAAIIYLYPSPLVCNAGAFVIGFSAAGG
ILQLGVSVMSEFFPKSKAKVTSIYMMMGGLANFVIPLITGYLSNIGLQYIIVLDFTFALLALITAIIVFIRYYRVFIIPK
NDVRFGERKFSTRLNTIKHRG
>SEQF1516_EDU85853.1 catalase HPII [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQQNEKNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTPPGAQPTASGSLKAPDTRNEKLNSLEDVRKGSENYAL
TTNQGVRIADDQNSLRAGSRGPTLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKIT
PVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFVHAVKPEPHWAIPQGQSAHDTFW
DYVSLQPETLHNVMWAMSDRGIPCSYRTMEGFGIHTFRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRR
ELWEAIEAGDFPEYELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFHPGHIVPGL
DFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHRMGIDTNPANYEPNSINDNWPRETPPGPKRG
GFESYQERVEGNKVRERSPSFGEYYSHPRLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAK
NLGIELTDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALKAKGVHAKLLYSRMGEV
TADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDANYYLMEAYKHLKPIALAGDARKFKATIKVADQGEEGIVE
ADSADGSFMDELLTLMAAHRVWSRIPKIDKIPA
>SEQF1516_EDU85854.1 phosphoenolpyruvate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNNGSSPLVLWYNQLGMKDVDRVGGKNASLGEMITNLSGMGVSVPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDD
VTQLAKAGAQIRQWIIDTPFQPELENAIREAYAQLSADDENASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAV
KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQVVFITSAWGLGEMVVQGAVNPDE
FYVHKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHGKQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEKHYGRPMDIE
WAKDGHTGKLFIVQARPETVRSRGQVMERYTLHSQGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVLVTDMTDPD
WEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGENVTVSCAEGDTGYVYAELLEFSVKSSSVETMP
DLPLKVMMNVGNPDRAFDFACLPNEGVGLARLEFIINRMIGVHPRALLEFDDQEPQLQNEIREMMKGFDSPREFYVGRLT
EGIATLGAAFYPKRVIVRLSDFKSNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFRDCFALECEAVKRVRNDMGLTN
VEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIPSNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVS
ELFDERNDAVKALLSMAIRAAKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK
>SEQF1516_EDU85855.1 ribosomal protein L20 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQYAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFI
NGLKKASVEIDRKILADIAVFDKVAFTALVEKAKAALA
>SEQF1516_EDU85856.1 major facilitator family transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNPYYPTALGLYFNYLVHGMGVILMSLNMASLETLWQSNAAGVSIVISSLGIGRLSVLLFAGLLSDRFGRRPFIMLGMC
CYMAFFFGILQTNNIIIAYVFGFLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLLVWAELWF
GWSFMIAAGIMFINALFLYRCTFPPHPGRRLPVIKKTTSSTEHRCSIIDLASYTLYGYISMATFYLVSQWLAQYGQFVAG
MSYTMSIKLLSIYTVGSLLCVFITAPLIRNTVRPTTLLMLYTFISFIALFTVCLHPTFYVVIIFSFVIGFTSAGGVVQIG
LTLMAERFPYAKGKATGIYYSAGSIATFTIPLITAHLSQRSIADIMWFDTAIAAIGFLLALFIGLRSRKKTRHHSLKENV
APGG
>SEQF1516_EDU85857.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAERKFLFACLIFALAIYAIHAFGLFDLLTDLPHLQTLIRQSGLFGYSLYILLFIIATLFLLPGSILVIAGGIVFGPFL
GTLLSLIAATLASSCSFLLARWMGRDLLLKYVGHSHTFQAIEKGIARNGIDFLILTRLIPLFPYNIQNYAYGLTTIAFWP
YTLISALTTLPGIVIYTVMASDLANEGITLRFILQLCLAGLALFILVQLAKLYARHKHVDLSASRRNPLTHPKNEG
>SEQF1516_EDU85858.1 pyrazinamidase/nicotinamidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRGEAVIASQDWHPANHGSFASQHGVEPYTPGQLDGLPQ
TFWPDHCVQNSEGAQLHPLLNQKAIAAVFHKGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFT
VLDALQLGYKVNVITDGCRGVNIQPQDSAHAFMEMSAAGATLYTLADWEETQG
>SEQF1516_EDU85859.1 succinylglutamic semialdehyde dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVGQACRAARAAFPRWARLSFAERQAVVERFAGLLERNKGELT
AIIARETGKPRWEAATELTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
AGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGCETGQALSALEDLDGLLFTGSANTGYQLHRQLSGQPEKIL
ALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQRCTCARRVLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGG
LISEQAAQQVFTAWQQLEAMGGRTLLAPRLLQAGTSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEAIRMANNTR
FGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGNHRPSAWYAADYCAWPMASLESDSLTLPATL
NPGLDFSDEVVR
>SEQF1516_EDU85860.1 major facilitator family transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDQITKPHCGARLDRLPDCRWHSSMFAIVAFGLLVCWSNAVGGLILAQLKALGWTDNSTTATFSAITTAGMFLGALVGGI
IGDKTGRRNAFILYEAIHIASMVVGAFSPNMDFLIACRFVMGVGLGALLVTLFAGFTEYMPGRNRGTWSSRVSFIGNWSY
PLCSLIAMGLTPLISAEWNWRVQLLIPAILSLIATALAWRYFPESPRWLESRGRYQEAEKVMRSIEEGVIRHTGKPLPPV
VIADDGKAPQAVPYSALLTGVLLKRVILGSCVLIAMNVVQYTLINWLPTIFMTQGINLKDSIVLNTMSMFGTPFGIFIAM
LVMDKIPRKTMGVGLLILIAVLGYIYSLQTSMLLITLIGFFLITFVYMYVCYASAVYVPEIWPTEAKLRGSGLANAVGRI
SGIAAPYAVAVLLSSYGVTGVFILLGAVSIIVAIAIATIGIETKGVSVESLSIDAVANK
>SEQF1516_EDU85861.1 cysteine desulfuration protein SufE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDRSPQNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKG
LIAVVFILYDQMTPQDVVNFDVRPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS
>SEQF1516_EDU85862.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAIDHAVQLSRDEPSLAIGMNFVLTMGKPLTAMPGLTRDG
VLGKWIWQLAEEDALPLEEITQELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEEGIALRIDRQPLSNAG
DLPANLRSSHGFSSAFYGEEISEALFLQVLDDSSHRGERSLEVMCHPAFVDNTIRQSAYCFPRLTELEVLTSASLKYAIA
ERGYRLGSYLDV
>SEQF1516_EDU85863.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRALFAVVLAFPLIALANPHYGPDVEVNVPPEVVSSGGQSAQPCTQCCVYQDKNYSEGAVIKAEGILLQCQRDDKTLST
NPLVWRRVKP
>SEQF1516_EDU85864.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYQRCFDNASETLFVAGKTPRLSRFAFSDDPKWESGHHVHDNETELIYVKKGVARFTIDSSLYVAHADDIVVIERGRLHA
VASDVNDPATTCTCALYGFQFQGAEENHLLQPHSCPVIAAGQGKEVIKTLFNELSVILPQSKNSQTSSLWDAFAYTLAIL
YYENFKNAYRSEQGYIKKDVLIKDILFYLNNNYREKITLEQLSKKFRASVSYICHEFTKEYRISPINYVIQRRMTEAKWS
LTNTELSQAEISWRVGYENVDHFAKLFLRHVGCSPSDYRRQFKNCFAEQEILSEFPQPVSLAG
>SEQF1516_EDU85865.1 inner membrane protein YdiK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNVRQPRDVAQILLSVLFLAIMIVACLWIVQPFILGFAWAGTVVIATWPVLLRLQKIMFGRRSLAVLVMTLLLVMVFII
PIALLVNSIVDGSGPLIKAISSGDMTLPDLAWLNTIPVIGAKLYAGWHNLLDMGGTAIMAKVRPYIGTTTTWFVGQAAHI
GRFMVHCALMLLFSALLYWRGEQVAQGIRHFATRLAGVRGDAAVLLAAQAIRAVALGVVVTALVQAVLGGIGLAVSGVPY
ATLLTVLMILSCLVQLGPLPVLIPAIIWLYWTGDTTWGTVLLVWSGVVGTLDNVIRPMLIRMGADLPLILILSGVIGGLI
AFGMIGLFIGPVLLAVSWRLFAAWVEEVPPPTDQPEEILEELGEIQKPNK
>SEQF1516_EDU85866.1 succinylornithine transaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPELREALNEQASKFWHTGNGYTN
ESVLRLAKKLIDATFADRVFFCNSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAP
LPPDIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNALLIFDEVQTGVGRTGELYAYMH
YGVTPDLLTTAKALGGGFPVGALLATEECASVMTVGTHGTTYGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVERLN
IINHRYGLFNEVRGLGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDRFAVACEHF
VSRGSS
>SEQF1516_EDU85867.1 IS1203 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLLDKLREQYGVGPVCSELHIAPSTDYHCQQQRHHPDKRSARAQRDDWLKREIQRVYDENHQVYGVRKVWRQLLREGIR
VARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVSAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFSGCIV
GWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYVSLAYTERLKEAKLLASTGSTGDSYDNAMAESINGLYKAEV
IHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHIPPAEAEKAYYASIRNDDLAA
>SEQF1516_EDU85868.1 rhodanese-like domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRVSQMTALAMALGLACASSWAAELAKPLTLDQLQQQNGKAIDTRSSAFYNGWPQTLNGPSGHEPAALNLSASWLDKMS
TEQLNAWIKQHNLKADAPVALYGNGKDVDAVKTRLQKAGFTHISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKEV
TAKPAGDWKVIEAARGAPKLYLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKHGIRHDTTVILYGRDVYAAARVA
QIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKVKAEPDFGVKIPAQPQLMLDMEQARGLLHRQDASLVSIRSWPEFI
GTTSGYSYIKPKGEIAGARWGHAGSDSTHMEDFHNPDGTMRSADDITAMWKAWNIKPDQQVSFYCGTGWRASETFMYARA
MGWNNVSVYDGGWYEWSSDPKNPVATGERGPDSSK
>SEQF1516_EDU85869.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAYELQALRHIFAMTIDECATWIAQTGDSESWRQWENGRCAIPDCVVEQLLAMRQQRKKHLHAIIEKINNRIGNNTMRF
FPDLTAFQQVYPDGNFIDWKIYQSVAAELYAHDLERLC
>SEQF1516_EDU85870.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFASLNAAADDSVFTVMDDPASAKKPFEGNLNAGYLAQSGNTKSSSLTADTTMTWYGQTTAWSLWGNASNTSSNDERSSE
KYAAGGRSRFNLTDYDYLFGQASWLTDRYNGYRERDVLTAGYGRQFLNGPVHSFRFEFGPGVRYDKYTDNASETQPLGYA
SGAYAWQLTDNAKFTQGVSVFGAEDTTLNSESALNVAINEHFGLKVAYNVTWNSEPPESAPEHTDRRTTLSLGYSM
>SEQF1516_EDU85871.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKVLLQNHPGSEKYSFNGWEIFNSNFERMIKENKTMLLCKWGFYLTCVVAVMFVFAAITSNGLNERGLITAGCSFLYLL
IMMGLIVRAGFKAKKEQLHYYQAKGIEPLSIEKLQALQLIAPYRFYHKQWSETLEFWPRKPEPGKDTFQYHVLPFDSIDI
ISKRRESLEEQWGIEDSESYCALMEHFLSGDHGANTFKANMEEAPEQVIALLNKFAVFPSDYISDCANHSSGKSSAKLIW
AAELSWMISISSTAFQNGTIEEELAWHYIMLASRKAHELFESEEDYQKNSLMGFLYWHICCYRRKLTDAELEACYRYDKQ
FWEHYSKKCRWPIRNVPWGASSVKYS
>SEQF1516_EDU85872.1 3-deoxy-7-phosphoheptulonate synthase, Trp-sensitive [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRTDELRTARIESLVTPAELALRYPVTPGVATHVTDSRRRIEKILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRN
QYQSRLEIVMRTYFEKPRTVVGWKGLISDPDLNGSYRINHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMTIYQTSGNPYGHIIMRGGKKPNY
HADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRRQLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYG
QSITDPCLGWEDTERLVEKLASAVDTRF
>SEQF1516_EDU85873.1 oxidoreductase, zinc-binding dehydrogenase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKALARFGKAFGGYKMIDVPQPICGPEDVVIEIKAAAICGADMKHYNVDSGSDEFNSIRGHEFAGCIAQVGEKVKDWKVG
QRVVSDNSGHVCGVCPACEQGDFLCCTEKVNLGLDNNTWGGGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPIC
NAYKSIAQQSKFLPGQDVVVIGTGPLGLFSVQMARIMGAVNIVVVGLQEDVAVRFPVAKELGATAVVNGSTEDVVARCQQ
ICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRVGMGFKPLDFSINDITAWNKSIIGHMAYDSTSWRNAIRLLASGAI
KVKPMITHRIGLSQWREGFDAMVDKTAIKVIMTYDFDE
>SEQF1516_EDU85874.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRHCGWLLGLLSLFSLATHASDWQEIKNEAKGQTVWFNAWGGDTAINRYLDWVSGEMKTHYAINLKIVRLADAADAVKRI
QTEAAAGRKTGGSVDLLWVNGENFRTLKEANLLQTDWAETLPNWRYVDTQLPVREDFSVPTEGAESPWGGAQLTFIARRD
VTPQPPQTPQALLEFAKANPGTVTYPRPPDFTGTAFLEQLLIMLTPDPAALNEAPNDATFARVTAPLWQYLDALHPYLWR
EGKDFPPSPARMDALLKAGTFRLSLTFNPAHAQQKIASGDLPASSYSFGFREGMIGNVHFVTIPANANASAAAKVVANFL
LSPDAQLRKADPAVWGDPSVLDPQKLPDGQRETLQSRMPQDLPPVLAEPHAGWVNALEQEWLHRYGTH
>SEQF1516_EDU85875.1 6-phospho-beta-glucosidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVSELWLVDVEGGKAKLDIIFDLCQRMIDNAGVPMKLYKTLDRREALKD
ADFVTTQLRVGQLPARELDERIPLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVEELCPNAWVINFTNPAGMVTEAVY
RHTGFKRFIGVCNIPIGMKMFIRDVLMLKDSDDLSIDLFGLNHMVFIKDVLVNGKSRFAELLDGVASGQLKASGVKNIFD
LPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEYYKGGARAQVVQKVEKQLFELYKNPELKVKPKELEQRGGAYYSDA
ACEVINAIYNDKQAEHYVNIPHHGHIDNIPADWAVEMTCTLGRDGATPHPRITHFDDKVMGLIHTIKGFEIAASNAALSG
EFNDVLLALNLSPLVHSDRDAELLAREMILAHEKWLPNFADCIAELKKAH
>SEQF1516_EDU85876.1 LysM domain/ErfK/YbiS/YcfS/YnhG family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRASLLTLTLIGAFSAIQAAWAVDYPLPPTGSRLVGQNQTYTVQEGDKNLQAIARRFDTAAMLILEANNTIAPVPKPGT
TITIPSQLLLPDAPRQGIIVNLAELRLYYYPPGENIVQVYPIGIGLQGLETPVMETRVGQKIPNPTWTPTAGIRQRSLER
GIKLPPVVPAGPNNPLGRYALRLAHGNGEYLIHGTSAPDSVGLRVSSGCIRMNAPDIKALFSSVRTGTPVKVINEPVKYS
VEPNGMRYVEVHRPLSAEEQQNVQTMPYTLPAGFTQFKDNKAVDQKLVDKALYRRAGYPVAVSSGATPTASNAPSVESAQ
NGEPEQGNMLRATQ
>SEQF1516_EDU85877.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLFSASFFTLAPESRRLAREKRNGKQRLKASQWRLFLYARFEK
>SEQF1516_EDU85878.1 DNA topoisomerase III [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPS
VTKQLNVIKRYLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCV
SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIW
QPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLY
ETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENEA
KVYNLISRQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLIKKGRYIHSTDAGKALFHS
LPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGGSADKKKAAPRKRSAKK
SPPADEAGSGAIA
>SEQF1516_EDU85879.1 6-phosphofructokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINVARAIAHLGGSATAIFPAGGATGEHLVSLLADENVPV
ATVEAKDWTRQNLHVHVEASGEQYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQNQG
IRCIIDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKAKRVVVSLGPQGALGVDSENCIQ
VVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMVRFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR
>SEQF1516_EDU85880.1 putative metal-dependent hydrolase, membrane-bound [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAEGHLLFSIACAVFAKNAELTPVLAQGDWWHIVPSAILTCLLPDIDHPKSFLGQRLKWISKPIARAFGHRGFTHSLLA
VFALLATFYLKVPESWFIPADALQGMVLGYLSHILADMLTPAGVPLLWPCRWRFRLPILVPQKGNQLERFICMALFVWSV
WMPHSLPENSAVRWSSQMINTLQIQFHRLIKHQVEY
>SEQF1516_EDU85881.1 esterase YdiI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIWKRKIPLEALNAMGEGNMVGLLDIRFEHIGDDTLEATMPVDSRTKQPFGLLHGGASVVLAESIGSVAGYLCTEGEQKV
VGLEINANHVRSAREGRVRGVCKPLHLGSRHQVWQIEISDEKGRLCCSSRLTTAIL
>SEQF1516_EDU85882.1 PTS system, N,N'-diacetylchitobiose-specific IIC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAMFVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLK
GIGGNVYNGTLGIMSLMAPFFIGMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
EMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQIIMDTISTPLASLGSVVGWAYVIF
VPLLWFFGIHGALALTALDNGIMTPWALENIATYQQYGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIA
SRRADYRQVAKLALPSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTMPTGLGAFF
NTNGSVVALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANALKF
>SEQF1516_EDU85883.1 HAD-superfamily hydrolase, subfamily IA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRNELPDTLGLRIDMVVDLWYARQPWNGPSRQEVVERVI
ARAISLVEETRPLLPGVREAVALCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAK
LGVDPLTCVALEDSVNGMIASKAARMRSIVVPAPEAQNDPRFVLANVKLSSLTELTAKDLLG
>SEQF1516_EDU85884.1 spheroplast protein Y [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKLTALFVASTLALGAANLAHAADTTTAAPADAKPMMHHKGKFGPHQDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPP
LEERRAMHDIIASDTFDKAKAEAQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATA
E
>SEQF1516_EDU85885.1 lipoprotein, NlpC/P60 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFCLILITALFLAGCSHHKAPPPNARLSDSITVIAGLNDQLQSWHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPR
ETKEQASIGTQIDKDELLPGDLVFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI
>SEQF1516_EDU85886.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTYQQAGRIAVLKRIMGWVIFIPALISTLISLLKFMNTRQENQEGINAVMLDFTHVMIDMMQANTPFLNLFWYNSPTPNF
NGGVNVMFWVIFILIFVGLALQDSGTRMSRQARFLREGVEDQLILEKAKGEEGLTREQIESRIVVPHHTIFLQFFSLYIL
PVICIAAGYVFFSLLGFI
>SEQF1516_EDU85887.1 vitamin B12 import system permease protein btuC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWFSPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQAL
FENPLAEPGLLGVSNGAGVGLIAAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALM
TWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPMLLWICCQSRPMNMLALGEISARQLGLPLWFWRNVLVAATG
WMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRALLPGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWL
LLKAGR
>SEQF1516_EDU85888.1 NAD+ synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLVLGISGGQDSTLAGKLCQMAINELRQETGNESLQFIA
VRLPYGVQADEQDCQDAIAFIQPDRVLTVNIKGAVLASEQALREACIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGT
DHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDRPSLPDEVALGVTYDNIDDYLEG
KNVPQQVARTIENWYLKTEHKRRPPITVFDDFWKK
>SEQF1516_EDU85889.1 sodium:dicarboxylate symporter family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFGLALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIV
MPLVFASILSAVARLHNASQLGKISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESIYVGKVSD
LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLTAIDTLQSWVMKLVRLVMQLTPYG
VLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFAVHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQ
TRRLGVPESIASFAASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGGATFAALIV
LPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKAILDSEDDAELAHH
>SEQF1516_EDU85890.1 excinuclease cho [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGESDTMPLYIGKSVNIRSRVLSHLRTPDEAAMLRQSRRI
SWICTAGEIGALLLEARLIKEQQPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQSIA
DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCWPWQGAVALKEQHPEMTQYHIIQ
NWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPLLSGNYEITELDPANDQRAS
>SEQF1516_EDU85891.1 hypothetical protein ECH7EC4501_4731 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEGKNGLKIVCDSGAGFSTEQAVFLANNLAKKMRSLKQKCNLRQYSYSMTVQSCIQCK
>SEQF1516_EDU85892.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKAPSLIAAIVLGLGISACGYFVGDGVKHLKTNNRYVNVRGLSEKEVRADTAELTIAINFKGNVPGELFPKLEEAQKKI
VAELNAQGINEKEIILGQWTSKRTDSFYLKDDPTMPRYNADGSVTIKTHNVAAVEKVVAKLNELQVATDGAIAESKVAYR
FNGIGALRAEMIAAATKDARNAALQFATDSGSQVGSISDASQGVFQIFASGSDEDDPTAINKTVRVVTTVTYALQD
>SEQF1516_EDU85893.1 IS1203 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAVRMVLESQGEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTTAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU85894.1 nitroreductase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDALELLINRRSASRLAEPAPTGEQLQNILRAGMRAPDHKSMQPWHFFVIEGEGRERFSAVLEQGAIAAGSDDKAIDKAR
NAPFRAPLIITVVAKCEENHKVPRWEQEMSAGCAVMAMQMAAVAQGFGGIWRSGALTESPVVREAFGCREQDKIVGFLYL
GTPQLKASTSINVPDPTPFVTYF
>SEQF1516_EDU85895.1 PTS system, N,N'-diacetylchitobiose-specific EIIA component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMDLDNIPDTQTEAEELEEVVMGLIINSGQARSLAYAALKQAKQGDFAAAKAMMDQSRMALNEAHLVQTKLIEGDAGEGK
MKVSLVLVHAQDHLMTSMLARELITELIELHEKLKA
>SEQF1516_EDU85896.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDTGMPTKRFDKKHWKMVVVLLAICGAMLLLRWAAMIWG
>SEQF1516_EDU85897.1 oxidoreductase, FAD-binding [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPQISQAPGVVQLVLNFLQELEQQGFTGDTATSYADRLTMSTDNSIYQLLPDAVVFPRSTADVALIARLAAQERYSSLI
FTPRGGGTGTNGQALNQGIIVDMSRHMNRIIEINPEEGWVRVEAGVIKDQLNQYLKPFGYFFAPELSTSNRATLGGMINT
DASGQGSLVYGKTSDHVLGLRAVLLGGDILDTQPLPVELAETLGKSNTTIGRIYNTVYQRCRQQRQLIIDNFPKLNRFLT
GYDLRHVFNDEMTEFDLTRILTGSEGTLAFITEARLDITRLPKVRRLVNVKYDSFDSALRNAPFMVEARALSVETVDSKV
LNLAREDIVWHSVSELITDVPDKEMLGLNIVEFAGDDEALIDERVNALCARLDELIASHQAGVIGWQMCRELAGVERIYA
MRKKAVGLLGNAKGAAKPIPFAEDTCVPPEHLADYIAEFRALLDSHGLSYGMFGHVDAGVLHVRPALDMCDPQQEILMKQ
ISDDVVALTAKYGGLLWGEHGKGFRAEYSPAFFGEELFAELRKVKAAFDPHNRLNPGKICPPEGLDAPMMKVDAVKRGTF
DRQIPIAVRQQWRGAMECNGNGLCFNFDARSPMCPSMKITQNRIHSPKGRATLVREWLRLLADRGVDPLKLEQELPESGV
SLRTLIARTRNSWHANKGEYDFSHEVKEAMSGCLACKACSTQCPIKIDVPEFRSRFLQLYHTRYLRPLRDHLVATVESYA
PLMARAPKTFNFFINQPLVRKLSEKHIGMVDLPLLSVPSLQQQMVGHRSANMTLEQLESLNAEQKARTVLVVQDPFTSYY
DAQVVADFVRLVEKLGFQPVLLPFSPNGKAQHIKGFLNRFAKTAKKTADFLNRMAKLGMPMVGVDPALVLCYRDEYKLAL
GEERGEFNVLLANEWLASALESQPVATVSGESWYFFGHCTEVTALPGAPAQWAAIFARFGAKLENVSVGCCGMAGTYGHE
AKNHKNSLGIYELSWHQAMQRLPRNRCLATGYSCRSQVKRVEGTGVRHPVQALLEIIK
>SEQF1516_EDU85898.1 protein FixA homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIITCFKLVPEEQDIVVTPEYTLNFDNADAKISQFDLNAIEAASQLATDDDEIAALTVGGSLLQNSKVRKDVLSRGPHS
LYMVQDAQLEHALPLDTAKALAAAVEKIGFDLLIFGKGSGDLYAQQVGLLVGEILQLPVINAVSAIQRQGNTLVIERTLE
DDVEVIELSVPAVLCVTSDINVPRIPSMKAILGAGKKPVNQWQASDIGWSQSAPLAELTGIRVPPQTERKHIILDNDSPE
AIAELAEHLKKALN
>SEQF1516_EDU85899.1 propionate CoA-transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEATTLITALADKYKQTQTPRNLSIISPTGLGDRADRGIS
PLAQEGLVKWALCGHWGQSPRISDLAEQNKIIAYNYPQGVLTQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKE
DLIKLVEFDNKEYLYYKAIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNNGGIVMMQVQKMVKKATLHPKSV
RIPGYLVDIVVVDPDQSQLYGGAPVNRFISGDFTLDDSTKLSLPLNQRKLVARRALFEMRKGAVGNVGVGIADGIGLVAR
EEGCADDFILTVETGPIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKFNGKIMGTG
GFIDISATSKKIIFCGTLTAGSLKTEIADGKLNIVQEGRVKKFIRELPEITFSGKIALERGLDVRYITERAVFTLKEDGL
HLIEIAPGVDLQKDILDKMDFTPVISPELKLMDERLFIDAAMGFVLPEAAH
>SEQF1516_EDU85900.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTQLDPTQLAIEFLRRDQSNLSPAQYLKRLKQLELEFADLLTLSSAELKEEIYFAWRLGVH
>SEQF1516_EDU85901.1 CTP pyrophosphohydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKMIEVVAAIIERDGKILLAQRPAQSDQAGLWEFAGGKVEPDESQQQALVRELNEELGIEATVGEYVASHQREVSGRIIH
LHAWHVPDFHGTLQAHEHQALVWCSPEEALQYPLAPADIPLLEAFMALRAARPAD
>SEQF1516_EDU85902.1 phenylalanyl-tRNA synthetase, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTTLRELPPEERPAAGAVINEAKEQVQQALNARKAELES
AALNARLAAETIDVSLPGRRIENGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWF
DATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNISFTNLKGTLHDFLRNFFEEDLQ
IRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVHPNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDL
RFLKQFK
>SEQF1516_EDU85903.1 ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATPLRYALIFLLWAMVAVIYAPLIPAALTLISPALSLTHWQALFADPQLPQALLATLVSTTIAAVGALLIALLVIVALW
PGPKWQRMCTRLPWLLAIPHVAFATSALLLFADGGLLYDYFPYFTPPMDKLGIGLGFTLAVKESAFLLWILAAVLSEKRL
LQQVIVLDSLGYSRWQCLNWLLLPSVAPALAMAMLAIVAWSLSVVDVAIILGPGNPPTLAVISWQWLTQGDADQQTKGAL
ASLLLMLLLAAYVLLGYLLWCTWRRTIPRVDGVRKPATPLLPGITLASFLPLTSVLCVVLLAILADQSTINSEALINSLT
MGLVATFIALLLLLLWLEWGPQRRQLWLWLPILLPALPLVAGQYTLALWLNMDGSWTAVVWGHLLWVMPWMLFILQPAWQ
RIDSRLILIAQTLGWSRAKIFFYVKCPLMLRPTLIAFAVGFSVSIAQYMPTLWLGAGRFPTLTTEAVALSSGGSNGILAA
LALWQLLLPLIIFALTALVAKWVGYVRQGLR
>SEQF1516_EDU85904.1 FeS assembly scaffold SufA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDMHSGTFNPQDFAWQGLTLTPAAAVHIRELVAKQPGMVGVRLGVKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVP
LQAMPFIDGTEVDFVREGLNQIFKFHNPKAQNECGCGESFGV
>SEQF1516_EDU85905.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVENESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRA
IILQSEGFCQDIVQALVAPLQQEMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSR
CGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIREERRENSRYASLRQCRMEVAEV
EALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRMY
>SEQF1516_EDU85906.1 vitamin B12 import ATP-binding protein BtuD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLARMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQ
QQTPPFAMPVWHYLTLHQHDKTRTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEP
MNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRREDVLTPPNLAQAYGMNFRRLDIE
GHRMLISTI
>SEQF1516_EDU85907.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLCVKNVSLRLPESCLLTNVNFTVDKGDIVTLMGPSGCGKSTLFSWMIGALAGQFSCTGELWLNEQRIDMLPTAQRQIGI
LFQDALLFDQFSVGQNLLLALPATLKGNARRNAVNDALERSGLDGAFHQDPATLSGGQRARVALLRALLAQPKALLLDEP
FSRLDVALRDNFRQWVFSEVRELAIPVVQVTHDLQDVPADSSVLDMAQWSENYNKLR
>SEQF1516_EDU85908.1 hypothetical protein ECH7EC4501_4724 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTAFHFYGFVYTDGLCGNCRKEQICATLGSVLTSKKIYLLERFTVFFIRLNMQR
>SEQF1516_EDU85909.1 protease 4 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQVSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKL
SRQLLGASSDRLQENSLFDIVNTIRQAKDDRNITGIVMDLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQY
YLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRDDMSPAAREADSRWIGELWQNYL
NTVAANRQIPAQQVFPGAQGLLEGLTKTGGDTAKYALENKLVDALASSAEIEKALTKEFGWSKADKNYRAISYYDYALKT
PADTGDSIGVVFANGAIMDGEETQGNVGGDTTAAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAARAAGKPVV
VSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGVHTDGVSTSPLADVSITRALPPEAQQMMQLS
IENGYKRFITLVADARHSTPEQIDKIAQGHVWTGQDAKANGLVDSLGDFDDAVAKAAELAKAKQWHLEYYVDEPTFFDKV
MDNMSGSVRAMLPDAFQAMLPAPLASVASTVKSESDKLAAFNDPQNRYAFCLTCANVR
>SEQF1516_EDU85910.1 3-dehydroquinate dehydratase, type I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTVTVKDLVIGTGAPKIIVSLMAKDIARVKSEALAYREADFDILEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFT
FRSAKEGGEQAISTEAYIALNRAAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRK
MQSFDADIPKIALMPQSTSDVLALLAATLEMQEQYADRPIITMSMAKTGVISRLAGEVFGSAATFGAVKKASAPGQISVN
DLRTVLTILHQA
>SEQF1516_EDU85911.1 kinase, pfkB family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNLDVICIGAAIVDIPLQPVSKNIFDVDSYPLERIAMTTGGDAINEATIISRLGHCTALMSRIGKDAAGQFILDHCRKE
NIDIQSLKQDVNIDTSINVGLVTEDGERTFVTNRNGSLWKLNIDDVDFARFSQAKLLSLASIFNSPLLDGKALTEIFTQA
KARQMNICADMIKPRLNETLDDICEALSYVNYAEAKLLTGKETLDEIADSFLACGVKTVVIKTGKDGCFIKRGDMTMKVP
AVAGITAIDTIGAGDNFASGFIAALLEGKNLRECARFANATAAISVLSVGATTGVKNRKLVEQLLEEYEG
>SEQF1516_EDU85912.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYQLLLIFMRYTDSRKLTPETDANHKTASPQPIRRISSQTLLGPDGKLIIDHDGQEYLLRKTQAGKLLLTK
>SEQF1516_EDU85913.1 exodeoxyribonuclease III [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDDMFPLEEVAKLGYNVFYHGQKGHYGVALLTKETPIAVRRGF
PGDEEEAQRRIIMAEIPSPLGNVTVINGYFPQGESRDHPIKFPAKAQFYQNLQNYLETELKRENPVLIMGDMNISPGDLD
IGIGEENRKRWLRTGKCSFLPEEREWMERLMSWGLVDTFRHANPQTADRFSWFDYRSKGFDDNRGLRIDLLLASQPLAEC
CVETGIDYEIRSMEKPSDHAPVWATFRR
>SEQF1516_EDU85914.1 carboxymuconolactone decarboxylase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGLPPLSKIPFILRPQAWLHRRHYGEVLSPIRWWGRIPFIFYLVSMFVGWLERKRSPLDPVVRSLVSARIAQMCLCEFCV
DITSMKVAERTGSSDKLLAVADWRQSPLFSDEERLALEYAEAASVTPPTVDDALRTRLAAHFDAQELTELTALIGLQNLS
ARFNSAMDIPAQGLCRIPEKRS
>SEQF1516_EDU85915.1 osmotically-inducible lipoprotein E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKNMAGILSAAAVLTMLAGCTAYDRTKDQFVQPVVKDVKKGMSRAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKA
ETYFVALDDTGHVINSGYQTCAEYDTDPQAAK
>SEQF1516_EDU85916.1 cysteine desulfurase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFI
NARSAEELVFVRGTTEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTL
FDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLYGPTGIGILYVKE
ALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSAQGLNNIAEYEQNLMHYALSQLESV
PDLTLYGPQNRLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVDRLVTGLQR
IHRLLG
>SEQF1516_EDU85917.1 acyl-CoA dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMRALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKC
GAPAFLITNGQCIHSMRRFGSAEQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEVEESDMVGEEGMGFLNVMYNFEM
ERLINAARSTGFAECAFEDAARYANQRIAFGKPIGHNQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKL
YCARTAMEVIDDAIQIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK
>SEQF1516_EDU85918.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKMQSRKIWYYRITLIILLFAMLLAWALLPGVHEFINRSVAAFAAVDQQGIERFIQSYGALAAVVSFLLMILQAIAAPL
PAFLITFANASLFGAFWGGSLSWTSSMAGAALCFFIARVMGREVVEKLTGKTVLDSMDGFFTRYGKHTILVCRLLPFVPF
DPISYAAGLTSIRFRSFFIATGLGQLPATIVYSWAGSMLTGGTFWFVTGLFILFALTVVIFMAKKIWLERQKRNA
>SEQF1516_EDU85919.1 sorbitol dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRK
FKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGTLVEPAAVGMHA
AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAKEDTIARCQQFTEDMGADI
VFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGASAINFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYD
YRDVQQAFEESVNNKRDIIKGVIKISD
>SEQF1516_EDU85920.1 inner membrane metabolite transport protein YdjE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYSGNVVLAKLVSNGWSNNFLNAAFTSALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAATGAAFVPDMYWLIFF
RFLMGTGMGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPMLSAAIGVVVIAFFSWRIMFLLGGIGILLAWFLSGKY
FIESPRWLAGKGQIAGAECQLREVEQQIEREKSIRLPPLTSYQSNSKVKVIKGTFWLLFKGEMLRRTLVAITVLIAMNIS
LYTITVWIPTIFVNSGIDVDKSILMTAVIMIGAPVGIFIAALIIDHFPRRLFGSTLLIIIAVLGYIYSIQTTEWAILIYG
LVMIFFLYMYVCFASAVYIPELWPTHLRLRGSGFVNAVGRIVAVFTPYGVAALLTHYGSITVFMVLGVMLLLCALVLSIF
GIETRKVSLEEISEVN
>SEQF1516_EDU85921.1 arginine N-succinyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSARIERAIKTWQGELPKSEQGYVFVLEDSETGTVAGICAIEVAV
GLNDPWYNYRVGTLVHASKELNVYNALPTLFLSNDHTGSSELCTLFLDPDWRKEGNGYLLSKSRFMFMAAFRDKFNDKVV
AEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLSQEAQDVIGQVHPQTAPARAVLE
KEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVEVAEGQPAQGDFPACLVANENYHHFRVVLVRTDPATERLILTAAQ
LDALKCHAGDRVRLVRLCAEEKTA
>SEQF1516_EDU85922.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQHYSVSWKKGLTALCLLAVAGLSGCDQKENAAAKVEYDGLSNSQPLRVDANNHTVTMLVQINGRFLTDDTRHGIVFKD
GSNGHKSLFMGYATPKAFYEALKEAGGTPGENMTMDNKETTHVTGSKLDISVNWQGAAKTYSFDEVIVDSNGKKLDMRFG
GNLTAAEEKKTGCLVCLDSCPVGIVSNATYTYGAVEKRGEVKFKGNASVLPANNTLATVTFKITE
>SEQF1516_EDU85923.1 protein FixC homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDDKFDAIVVGAGVAGSVAALVMARAGLDILVIERGDSAGCKNMTGGRLYAHTLEAIIPGFAASAPVERKVTREKISFL
TEESAVTLDFHREQPDVPQHASYTVLRNRLDPWLMEQAEQAGAQFIPGVRVDALVREGNKVTGVQAGDDILEANVVILAD
GVNSMLGRSLGMVPASDPHHYAVGVKEVIGLTPEQINDRFNITGEEGAAWLFAGSPSDGLMGGGFLYTNKDSISLGLVCG
LADIAHAQKSVPQMLEDFKQHPAIRPLISGGKLLEYSAHMVPEGGLAMVPQLVNDGVMIVGDAAGFCLNLGFTVRGMDLA
IASAQAAATTVIAAKERADFSASSLAQYKRELEQSCVMRDMQHFRKIPALMENPRLFSQYPRMVADIMNEMFTIDGKPNQ
PVRKMIMGHAKKIGLINLLKDGIKGATAL
>SEQF1516_EDU85924.1 hypothetical protein ECH7EC4501_4650 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRQFDHIVPLGASDLLKKVAIAANSLAASLSSFYFQAQEQIILTTRA
>SEQF1516_EDU85925.1 threonyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGELVDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLG
HAIKQLWPHTKMAIGPVIDNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSIL
DENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRIYGTAWADKKALNAYLQRLEEAA
KRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRELEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTT
SSENREYCIKPMNCPGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQIRDEVNGC
IRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNIPFEYQLGEGAFYGPKIEFTLYDCLDRAWQC
GTVQLDFSLPSRLSASYVGEDNERKVPVMIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQ
KLSNAGIRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKIAVRTRRGKDLGSMDVNEVIEKLQQEIRSRSLKQL
EE
>SEQF1516_EDU85926.1 translation initiation factor IF-3 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIR
FLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVESFPTKIEGRQMIMVLAPKKKQ
>SEQF1516_EDU85927.1 protein FixB homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQLNSVWVFSDNPERYAELFGGAQQWGQQVYAIVQNTDQAQAVMPYGPKCIYVLEQNDALQRTENYAESIAALLKDKHP
AMLLLAATKRGKALAARLSVQLNAALVNDATAVDIVDGHICAEHRMYGGLAFAQEKINSSLAIITLAPGVQEPCTSDTSH
QCPTETVPYVAPRHEILCRERRAKAASSVDLSKAKRVVGVGRGLAAQDDLKMVHELAAVLNAEVGCSRPIAEGENWMERE
RYIGVSGVLLKSDLYLTLGISGQIQHMVGGNGAKVIVAINKDKNAPIFNYADYGLVGDIYKVVPALISQLSR
>SEQF1516_EDU85928.1 succinylarginine dihydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAWEVNFDGLVGLTHHYAGLSFGNKASTRHRFQVSNPRLAAKQGLLKMKTLADAGFPQAVIPPHERPFIPVLRQLGFSG
SDEQVLEKVVRQAPHWLSSVSSASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVTESLLKAIFNDEEKFS
VHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREASEAVARLNQVNPQQVIFAQQNPD
VIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLANLRARVNGFMAIEVPATQVSVSDAVSTYLFNSQLLSRDDGSMMLV
LPQECREHAGVWGYLNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTQEERRAVNPAVMMNDTLFNALNDWVDR
YYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG
>SEQF1516_EDU85929.1 integration host factor, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVT
FRPGQKLKSRVENASPKDE
>SEQF1516_EDU85930.1 fructose-bisphosphate aldolase, class II family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLADIRYWENDATNKRYAIAHFNVWNAEMLMGVIDAAEEAKSPVIISFGTGFVGNTSFEDFSHMMVSMAQKATVPVITHW
DHGRSMEIIHNAWTHGMNSLMRDASAFDFEENIRLTKEAVDFFHPLGIPVEAELGHVGNETVYEEALAGYHYTDPDQAAE
FVERTGCDSLAVAIGNQHGVYTSEPQLNFEVVKRVRDAVSVPLVLHGASGISDADIKTAISLGIAKINIHTELCQAAMVA
VKENQDQPFLHLEREVRKAVKERALEKIKLFGSDGKAE
>SEQF1516_EDU85931.1 transcriptional regulator, DeoR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAKDRIQAIKQMVANDKKVTVSNLSGIFQVTEETIRRDLEKLEDEGFLTRTYGGAVLNTAMLTENIHFYKRASSFYEEK
QLIARKALPFIDNKTTMAADSSSTVMELLKLLQDRSDLTLLTNSAEAIHVLAQSEIKVVSTGGELNKNTLSLQGRITKEI
ISRYHVDIMVMSCKGLDINSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFVQLADFSHINYIITDKSPGAEWI
AFCKDNNIQLVW
>SEQF1516_EDU85932.1 succinylglutamate desuccinylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNFLALTLTSKKPVITEREINGVRWRWLGDGVLELTPLTPPQGALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWR
LLVILGNPPALKQGKRYCHSDMNRMFGGRWQLFAESGETCRARELEQCLEDFYDQGKESVRWHLDLHTAIRGSLHPQFGV
LPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFGQNDLRQFAVTASAIAALLSGES
VGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFMPFKKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEK
IS
>SEQF1516_EDU85933.1 vitamin B12 transport periplasmic protein btuE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDSILTTVVKDIDGEVTTLEKYAGNVLLIVNVASKCGLTPQYEQLENIQKAWADRGFVVLGFPCNQFLEQEPGSDEEIK
TYCTTTWGVTFPMFSKIEVNGEGRHPLYQKLISAAPTAVAPEESGFYARMVSKGRAPLYPDDILWNFEKFLVGRDGLVIQ
RFSPDMTPEDPIVMESIKLALAK
>SEQF1516_EDU85934.1 CDP-alcohol phosphatidyltransferase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDRHLHPRIKPLLHQCVRVLDKPGITPDGLTLVGFAIGVLALPFLALGWYLAALVVILLNRLLDGLDGALARRRGLTDA
GGFLDISLDFLFYALVPFGFILAAPQQNALAGGWLLFAFIGTGSSFLAFAALAAKYQIDNPGYAHKSFYYLGGLTEGTET
ILLFVLGCLFPAWFAWFAWIFGALCWMTTFTRVWSGYLTLKSLQRQ
>SEQF1516_EDU85935.1 phenylalanyl-tRNA synthetase, beta-subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFHGVVVGEVVECAQHPNADKLRVTKVNVGGDRLLDIVCG
APNCRQGLRVAVATIGAVLPGDFKIKAAKLRGEPSEGMLCSFSELGISDDHNGIIELPADAPIGTDIREYLKLDDNTIEI
SVTPNRADCLGIIGVARDVAVLNQLPLVEPEIVPVGATIDDTLPITVEAPEACPRYLGRVVKGINVKAPTPLWMKEKLRR
CGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIEGGIVVRMAKEGETLVLLDGTEAKLNADTLVIADHNKALAMGGIFGGE
HSGVNDETQNVLLECAFFSPLSITGRARRHGLHTDASHRYERGVDPALQYKAMERATRLLIDICGGEAGPVIDITNEATL
PKRATITLRRSKLDRLIGHHIADEQVTDILRRLGCEVTEGKDEWQAVAPSWRFDMEIEEDLVEEVARVYGYNNIPDEPVQ
ASLIMGTHREADLSLKRVKTLLNDKGYQEVITYSFVDPKVQQMIHPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQ
NRQQNRVRIFESGLRFVPDTQAPLGIRQDLMLAGVICGNRYEEHWNLAKETVDFYDLKGDLESVLDLTGKLNEVEFRAEA
NPALHPGQSAAIYLKGERIGFVGVVHPELERKLDLNGRTLVFELEWNKLADRVVPQAREISRFPANRRDIAVVVAENVPA
ADILSECKKVGVNQVVGVNLFDVYRGKGVAEGYKSLAISLILQDTSRTLEEEEIAATVAKCVEALKERFQASLRD
>SEQF1516_EDU85936.1 methionine-R-sulfoxide reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVYHCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRY
IKDLSHGMQRIEIRCGNCDAHLGHVFPDGPQPTGERYCVNSASLRFTDGENGEEING
>SEQF1516_EDU85937.1 putative shikimate 5-dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEVDNDSFPGAIEGLKALKMRGTGVSMPNKQLACEYVDE
LTPAAKLVGAINTIVNDDGYLRGYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDKF
FDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENKSLVNDISLLHPGLLVTECVYNPHMTK
LLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFPLEYVKQVMGFGA
>SEQF1516_EDU85938.1 iron-sulfur cluster-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQNATVNVDIKLGVNKFHVDEGHPHIILAANPDINEFRKLMKACPAGLYKQDDAGNIHFDSAGCLECGTCRVLCGNTIL
EQWQYPAGTFGIDFRYG
>SEQF1516_EDU85939.1 transcriptional regulator ChbR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDYYEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHHQ
SFYEFGATRILNVGISKRFFEQHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRHY
REEQVIDDVPQWLKSTVEKMHDKEQFSESALENMVTLSAKSQEYLTRATQRYYGKTPMQIINEIRINFAKKQLEMTNYSV
TDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLTEFNQ
>SEQF1516_EDU85940.1 short-chain-fatty-acid--CoA ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVTLTFNEQRRAAYRQQGLWGDASLADYWQQTARAMPDKIAVVDNHGASYTYSALDHAASCLANWMLAKGIESGDRIAF
QLPGWCEFTVIYLACLKIGAVSVPLLPSWREAELVWVLNKCQAKMFFTPTLFKQTRPVDLILPLQNQLPQLQQIVGVDKL
APATSSLSLSQIIADNTPLTTAITTHGDELAAVLFTSGTEGLPKGVMLTHNNILASERAYCARLNLTWQDVFMMPAPLGH
ATGFLHGVTAPFLIGARSVLLDIFTPDACLALLEQQRCSCMLGATPFVYDLLNLLEKQPADLSALRFFLCGGTTIPKKVA
RECQQRGIKLLSVYGSTESSPHAVVNLDDPLSRFMHTDGYAAAGVEIKVVDDARKTLPPGCEGEEASRGPNVFMGYFDEP
ELTARALDEEGWYYSGDLCRMDEAGYIKITGRKKDIIVRGGENISSREVEDILLQHPKIHDACVVAMPDERLGERSCAYV
VLKAPHHSLSLEEVVAFFSRKRVAKYKYPEHIVVIEKLPRTASGKIQKFLLRKDIMRRLTQDVCEEIE
>SEQF1516_EDU85941.1 FeS assembly protein SufD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGLPNSSNALQQWHHLFEAEGTKRSPQAQQHLQQLLRTGLPTRKHENWKYTPLEGLTNSQFVSIAGEISPQQRDALALT
LDAVRLVFVDGRYVPALSDATEGSGYEVSINDDRQGLPDAIQAEVFLHLTESLAQSVTHIAVKRGQRPAKPLLLMHITQG
VAGEEVNTAHYRHHLELAEGAEATVIEHFVSLNDARHFTGARFSINVAANAHLQHIKLAFENPLSHHFAHNDLLLADDAT
AFSHSFLLGGAVLRHNTSTQLNGENCTLRINSLAMPVKNEVCDTRTWLEHNKGFCNSRQLHKTIVSDKGRAVFNGLINVA
QHAIKTDGQMTNNNLLMGKLAEVDTKPQLEIYADDVKCSHGATVGRIDDEQMFYLRSRGINQQDAQQMIIYAFAAELTEA
LRDEGLKQQVLTRIGQRLPGGAR
>SEQF1516_EDU85942.1 cell division activator CedA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVWMLRGKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQEGEVTE
>SEQF1516_EDU85943.1 FeS assembly protein SufB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVRAISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHY
DKLNYQDYSYYSAPSCGNCDDTCASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVVSDGTFIYVPKGVRCPMELSTYFRINAEKTGQFERTIL
VADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKNAEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSE
TGSAITWKYPSCILRGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKIMPTATNAR
NFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQRGISEEDAISMIVNGFCKDVFSELPLEFAV
EAQKLLAISLEHSVG
>SEQF1516_EDU85944.1 oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQV
VVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVEASLQRLGFDYIDIYMTHWQSVPPFYTPIAETVAVLNELKAE
GKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARA
NKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREM
AEVLGR
>SEQF1516_EDU85945.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLITAPCRALLALPFCYAFSAAGEEARPAEHDDTKTPAITSTSSPSFRFYGELGVGGYMDLEGENKHKYSDGTYIEGGL
EMKYGSWFGLIYGEGWTVQADHDGNAWVPDHSWGGFEGGINRFYGGYRTNDGTEIMLSLRQDSSLDDLQWWGDFTPDLGY
VIPNTRDIMTALKVQNLSGNFRYSVTATPAGHHDESKAWLHFGKYDRYDDKYTYPAMMNGYIQYDLAEGITWMNGLEITD
GTGQLYLTGLLTPNFAARAWHHTGRADGLDVPGSESGMMVSAMYEALKGVYLSTAYTYAKHRPDHADDETTSFMQFGIWY
EYGGGRFATAFDSRFYMKNASNDPSDQIFLMQYFYW
>SEQF1516_EDU85946.1 gram-negative pili assembly chaperone protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKRTFAMIFTLLCSFCIGQALAGGIVLQRTRVIYDASRKEAALPVANKGAETPYLLQSWVDNIDGTSRAPFIITPPLIR
LEAGDDSSLRIIKTADNLPENKESLFYINVRAIPAKKKSDDVNANELTLVFKTRIKMFYRPAHLKGRVSDAWKSLEFKRS
DHSLNIYNPTEYYVVFAGLAVDKADLTSKIEYIAPGEHKQLPLPASGGKNVKWAAINDYGGSSGTETRPLQ
>SEQF1516_EDU85947.1 pirin family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLNQEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEG
NHVQASAGEALLLSTQPGVSYSEHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQHLIASPEGAMGSLQLRQQVW
LHHIVLDKGESANFQLHGPRTYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITLVADSPLRALLIDLPV
>SEQF1516_EDU85948.1 hypothetical protein ECH7EC4501_5447 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFTLPGGIAIPEMIDIDHISAFKLLTFLFHPMKSFIFK
>SEQF1516_EDU85949.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKAATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKN
KDWSRVKFGAGRYRLFFRYSEKEKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWETLTRETEETH
>SEQF1516_EDU85950.1 N-acetylglucosamine-6-phosphate deacetylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVSVTERDAELLCPAYIDTHVHGGAGVDVMDDAPDVLDKLAMHKA
REGVGSWLPTTVTAPLSTIHAALKRIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHT
LRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMTGLHHREPGMVGAGLTDKRAWLE
LIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGMPDGRYTLCGEEVQMHGGVVRTASGGLAGSTLSVDAAVRNMVELT
GVTPAEAIHMASLHPARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF
>SEQF1516_EDU85951.1 putative inner membrane protein YhaH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKMLGWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDR
SAWWALLFLIPFIGWLIIIVFNCQAGTPGENRFGPDPKLEP
>SEQF1516_EDU85952.1 HTH-type transcriptional regulator EbgR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLKDIAIEAGVSLATVSRVLNDDPTLNVKEETKHRILEIAEKLEYKTSSARKLQTGAVNQHHILAIYSYQQELEINDP
YYLAIRHGIETQCEKLAIELTNCYEHSGLPDIKNVTGILIVGKPTPALRAAASALTDNICFIDFHEPGSGYDAVDIDLAR
ISKEIIDFYINQGVNRIGFIGGEDEPGKADIREVAFAEYGRLKQVVREEDIWRGGFSSSSGYELAKQMLAREDYPKALFV
ASDSIAIGVLRAIHERGLNIPQDISLISVNDIPTARFTFPPLSTVRIHSEMMGSQGVNLVYEKARDGRALPLLVFVPSKL
KLRGTTR
>SEQF1516_EDU85953.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDDVTVNQTDNVTGREFTSATLSSTNWQYACSCSAGKAVKLVYMVSPVLTTTGHQTGYYKLNDSLDIKTMNRPGNPGD
>SEQF1516_EDU85954.1 putative sugar isomerase, AgaS family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALHSALNNFLEPLLRKENLRIILTGAGTSAFIGDIIAPWLASHTG
KNFSAVPTTDLVTNPMDYLNPAHPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFAVL
MPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGVFGYAPWKRIVYLGSGGLQGAAR
ESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDNETLVVVFVSSHPYTRQYDLDLLAELHRDNQAMRVIAIAAESSDIVA
AGPHIILPPSRHFIDVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVIIHPWQA
>SEQF1516_EDU85955.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNLTYLQGYPEQLLSQVRTLINEQRLGDVLAKRYPGTHDYATDKALWQYTQDLKNQFLRNAPPINKVMYDNKIHVLKNA
LGLHTAVSRVQGGKLKAKAEIRVATVFRNAPEPFLRMIVVHELAHLKEKEHNKAFYQLCCHMEPQYHQLEFDTRLWLTQL
SLGQDKI
>SEQF1516_EDU85956.1 D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPLLIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNF
PQDALILGGDHLGPNRWQNLPAAQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCL
EHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWPRIIALVVQPGVEFDHTNVIDYQ
PAKATALSQMVESYETLIFEAHSTDYQTPQSLRQLVIDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVL
ENVMLNRPEYWQSHYHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQYVKVRSGEL
QPTPRELIINHIQDILAQYHTACEGQ
>SEQF1516_EDU85957.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEKANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQY
RLNAMIATTVVLLLLALIGGIWTLRKSRKSTLLRHTRHELANDRQLLEEESREQ
>SEQF1516_EDU85958.1 DnaA initiator-associating protein DiaA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALN
TDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVE
IRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDD
>SEQF1516_EDU85959.1 PTS system, mannose/sorbose-specific, IIA component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSIILTGHGGFASGMEKAMKQILGEQSQFIAIDFPETSSTALLTSQLEEAIAQLDCEDGIVFLTDLLGGTPFRVASTLA
MQKPGCEVITGTNLQLLLEMVLEREGLSGEEFRVQALECGHRGLTSLVDELGRCHEECPVEEGI
>SEQF1516_EDU85960.1 sodium:serine/threonine symporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTQRSPGLFRRLAHGSLVKQILVGLVLGILLAWISKPAAEAVGLLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTN
IRPILFLYLLGTFSAALAAVVFSFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLG
FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQLLVVLVGCMLLVALVVNPLLVWW
KIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGI
PVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTDVLFTAAAC
QAEDDRLANSALRN
>SEQF1516_EDU85961.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAELEGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAA
ALGALGGNANAGLEVLKDATAQAIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHDG
VVFTQQACVAEGEQESPLSVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEGLSGKWGLHIGATLEKQCERGLL
AKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQGITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLS
ALCAATTAAMGAAAGMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDTAVTGNEGI
VAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR
>SEQF1516_EDU85962.1 NAD dependent epimerase/dehydratase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGVFNPHDPQLTDALAQVTDPIDIVFCCLGTTRREAGSK
EAFIHADYTLVVDTALTGRRLGAQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNE
TLFAPLFRLLPGNWKSIDARDVARVMLAEAMRPEHEGVTILSSSELRKRAE
>SEQF1516_EDU85963.1 PTS system, D galactosamine-specific, IIB component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSPNILLTRIDNRLVHGQVGVTWTSTIGANLLVVVDDVVANDDIQQKLMGITAETYGFGIRFFTIEKTINVIGKAAPHQ
KIFLICRTPQTVRKLVEGGIDLKDVNVGNMHFSEGKKQISSKVYVDDQDLTDLRFIKQRGVNVFIQDVPGDQKEQIPD
>SEQF1516_EDU85964.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWNMLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFG
VWSAWRLVKTTLKQQQLRG
>SEQF1516_EDU85965.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METLTAISRWLAKQHVVTWCVQQEGELWCANAFYLFDVQKVAFYILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGV
QFKGEIRRLEGEESDLARKAYNRRFPVARMLSAPVWEIRPDEIKFTDNTLGFGKKMIWLRGSGTEQA
>SEQF1516_EDU85966.1 glycerate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADGGEGTVEAMIAATQGSERHAWVTGPLGEKVNASWGIS
GDGKTAFIEMAAASGLELVPAEKRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAMIVELDNNLSHYAEVIKKALHVD
VKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTALNLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVI
GIAGSLTDDVGVVHQHGIDAVFSVLTSIGTLDEAFRGAYDNICRASRNIAATLAIGMRNAG
>SEQF1516_EDU85967.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVPSTFSRLKAARCLPVVLAALIFVGCGTHTPDQSTAYMQGTAQADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTG
QAVELFNQLPQELNDSQRREKTLLAVEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIA
QEPLLGAKEKQQNIDATWQALSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDPDMMKAGIADWQKRYPNNPGAKM
LPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTIQQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTADGVASPAQ
ASVSDLTGDQPAAQPVPVSAPATSTAAVSAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNVEELLKSNT
PLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIPRSSLGDRVANAFAQEWQKLGGGTVLQQKFG
STSELRAGVNGGSGIALTGTPITPRATTDSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGS
QSGATLYASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMGVDAWSLANHFSQMRQV
QGFEINGNTGSLTANPDCVINRKLSWLQYQQGQVVPAS
>SEQF1516_EDU85968.1 putative inner membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLPAAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAAS
LGCWVSYIQGRWLGNTRTVQNWLSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMS
GLLWVLILTTLGYMLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGNRG
>SEQF1516_EDU85969.1 Exu regulon transcriptional regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEITEPRRLYQQLAADLKERIEQGVYLVGDKLPAERFIADEKNVSRTVVREAIIMLEVEGYVEVRKGSGIHVVSNQPRHQ
QAADNNMEFANYGPFELLQARQLIESNIAEFAATQVTKQDIMKLMAIQEQARGEQCFRDSEWDLQFHIQVALATQNSALA
AIVEKMWTQRSHNPYWKKLHEHIDSRTVDNWCDDHDQILKALIRKDPHAAKLAMWQHLENTKIMLFNETSDDFEFNADRY
LFAENPVVHLDTATSGSK
>SEQF1516_EDU85970.1 sterol-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDKLRSRIVHLGPSLLSVPVKLTPFALKRQVLEQVLSWQFRQALDDGELEFLEGRWLSIHVRDIDLQWFTSVVNGKLVV
SQNAQADVSFSADASDLLMIAARKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRMMLLQLADFVEAGMK
TAPETKQTSVGEPC
>SEQF1516_EDU85971.1 tagatose-1,6-bisphosphate aldolase agaY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSPVILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALH
LDHHESLDDIRRKVHAGVRSAMIDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEA
KRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFVRRTIELGVTKVNVATELKIAFA
GAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKINVCGSANRISA
>SEQF1516_EDU85972.1 transcriptional regulator, PadR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHHHEGCCKHEGQPRHEGCCKGEKSEHEHCGHGHQHEHGQCCGGRHGRGGGRRQRFFGHGELRLVILDILSRDDSHGYE
LIKAIENLTQGNYTPSPGVIYPTLDFLQEQSLITIREEEGGKKQIALTEQGAQWLEENREQVEMIEERIKARCVGAALRQ
NPQMKRALDNFKAVLNLRVNQSDITDAQIKKIIAVIDRAAFDITQLD
>SEQF1516_EDU85973.1 hypothetical protein ECH7EC4501_5485 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVVAAISYGIVDLYRYVIFLIWQNRMIVETGSKTRVG
>SEQF1516_EDU85974.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU85975.1 fimbrial usher family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIMAAVPGQKLVHCNNKYKNTGHQGMPQRHHQGHKRTPKQLALIIKRCLPMVLTGSGMLCTTANAEEYYFDPIMLETTKS
GMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQKKITFTANAEQLLQPQFTVEQLRELGIKVDEIPALAEKDDDSVINS
LEQIIPGTAAEFDFNHQRLNLSIPQIALYRDARGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNMQNGANF
GPWRLRNYSTWTRNDQASSWNTISSYLQRDIKALKSQLLLGESATSGSIFSSYNFTGVQLASDDNMLPNSQRGFAPTVRG
IANSSAIVTIRQNGYVIYQSNVPAGAFEINDLYPSSNSGDLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRY
RADANSDSKEPEFAEATAIYGLNNTFTLYGGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDNQHSFHGYQWRTQ
YIKDIPETNTNIAVSYYRYTNDGYFSFDEANTRNWDYNSRQKSEIQFNISQTIFDGVSLYASGSQQDYWGNNEKNRNISV
GVSGQQWGIGYSLNYQYSRYTDQNNDRALSLNLSIPLERWLPRSRVSYQMTSQKDRPTQHEMRLDGSLLDDGRLSYSLEQ
SLDDDNNHNSSVNASYRSPYGTFSAGYSYGNDSSQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDANGASGVRIQNYPGI
ATDPFGYAVVPYLTTYQENRLSVDTTQLPDNVDLEQTTQFVVPNRGAMVAARFNANIGYRVLVTVSDRNGKPLPFGALAS
NDDTGQQSIVDEGGILYLSGISSKSQSWTVRWGNQADQQCQFAFSTPDSEPTTSVLQGTAQCH
>SEQF1516_EDU85976.1 PTS system N-acetylgalactosamine-specific, IID component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASNQTTLPNVSENEETLLTGVNENVYEDQSIGAELTKKDINRVAWRSMLLQASFNYERMQASGWLYGLLPALKKIHTNK
RDLARAMKGHMGFFNTHPFLVTFVIGIILAMERSKQDVNSIQSTKIAVGAPLGGIGDAMFWLTLLPICGGIGASLALQGS
ILGAVVFIVLFNVVHLGLRFGLAHYAYRMGVAAIPLIKANTKKVGHAASIVGMTVIGALVATYVRLSTTLEITAGDAVVK
LQADVIDKLMPAFLPLVYTLTMFWLVRRGWSPLRLIAVTVVLGIVGKFCHFL
>SEQF1516_EDU85977.1 putative inner membrane protein YqjF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILSIDSNDANTAPLHKKTISSLSGAVESMMKKLEDVGVLVARILMPILFITAGWGKITGYAGTQQYMEAMGVPGFMLPL
VILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKNLTISGGFLLLAITGPGAYSIDRLLNKKW
>SEQF1516_EDU85978.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYRIALAVSLFALSAGSYATTLCQEKEQNILKEISYAEKHQNQNRIDGLNKALSEVRANCSDSQLRADHQKKIAKQKDE
VAERQQDLAEAKQKGDADKIAKRERKLAEAQEELKKLEARDY
>SEQF1516_EDU85979.1 tryptophan-specific transport protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWSMAALIFTWFCMLHSGLMILEANLNYRIGSSFDTITK
DLLGKGWNVVNGISIAFVLYILTYAYISASGSILHHTFAEMSLNVPARAAGFGFALLVAFVVWLSTKAVSRMTAIVLGAK
VITFFLTFGSLLGHVQPATLFNVAESNASYAPYLLMTLPFCLASFGYHGNVPSLMKYYGKDPKTIVKCLVYGTLMALALY
TIWLLATMGNIPRPEFIDIAEKGGNIDVLVQALSGVLNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSAV
GRLKTALLTFAPPVVGGLLFPNGFLYAIGYAGLAATIWAAIVPALLARASRKRFGSPKFRVWGGKPMITLILVFGVGNAL
VHILSSFNLLPVYQ
>SEQF1516_EDU85980.1 putative type 1 fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKVTKTAIAGLLALFAGNAAATDGEIVFDGEILKSACEINDSDKKIEVALGHYNAEQFRSVGDRSPKIPFTIPLVNCPV
TGWEHDNGNVEASFRLWLETRDNGTVPNFPNLAKVGSFAGTAATGVGIRIDDAESGNLMPLNAMGNDNTVYQIPADSAGI
VNVDLIAYYVSTVEASEITPGEADAVVNVTLDYR
>SEQF1516_EDU85981.1 GIY-YIG catalytic domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKGELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVA
EGAGFAKLLSSLQTPEIKSD
>SEQF1516_EDU85982.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGLVATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVD
EKYRGQGLARQLVYEGLDSLNEFGYAAVVTLGDPALYSRFGFELAAHHDLRCRWPGTESAFQVHRLADDALNGVTGLVEY
HEHFNRF
>SEQF1516_EDU85983.1 PTS system, N-acetylgalactosamine-specific, IIB component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPNIVLSRIDERLIHGQVGVQWVGFAGANLVLVANDEVAEDPVQQNLMEMVLAEGIAVRFWTLQKVIDNIHRAADRQKIL
LVCKTPADFLTLVKGGVPVNRINVGNMHYANGKQQIAKTVSVDAGDIAAFNDLKAAGVECFVQGIPTEPAVDLFKLL
>SEQF1516_EDU85984.1 beta-galactosidase, subunit alpha [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRWENIQLTHENRLAPRAYFFSYDSVAQARTFARETSSLFLPLSGQWNFHFFDHPLQVPEAFTSELMADWGHITVPAMW
QMEGHGKLQYTDEGFPFPIDVPFVPSDNPTGAYQRIFTLSDGWQGKQTLIKFDGVETYFEVYVNGQYVGFSKGSRLTAEF
DISAMVKTGDNLLCVRVMQWADSTYVEDQDMWWSAGIFRDVYLVGKHLTHINDFTVRTDFDEAYCDATLSCEVVLENLAA
SPVVTTLEYTLFDGERVVHSSAIDHLAIEKLTSASFAFTVEQPQQWSAESPYLYHLVMTLKDANGNVLEVVPQRVGFRDI
KVRDGLFWINNRYVMLHGVNRHDNDHRKGRAVGMDRVEKDLQLMKQHNINSVRTAHYPNDPRFYELCDIYGLFVMAETDV
ESHGFANVGDISRITDDPQWEKVYVERIVRHIHAQKNHPSIIIWSLGNESGYGCNIRAMYHAAKALDDTRLVHYEEDRDA
EVVDIISTMYTRVPLMNEFGEYPHPKPRIICEYAHAMGNGPGGLTEYQNVFYKHDCIQGHYVWEWCDHGIQAQDDNGNVW
YKFGGDYGDYPNNYNFCLDGLIYSDQTPGPGLKEYKQVIAPVKIHALDLTRGELKVENKLWFTTLDDYTLHAEVRAEGET
LATQQIKLRDVAPNSEAPLQITLPQLDAREAFLNITVTKDSRTRYSEAGHSIATYQFPLKENTAQPVPFAPNNARPLTLE
DDRLSCTVRGYNFAITFSKTSGKPTSWQVNGESLLTREPKINFFKPMIDNHKQEYEGLWQPNHLQIMQEHLRDFAVEQSD
GEVLIISRTVIAPPVFDFGMRCTYIWRIAADGQVNVALSGERYGDYPHIIPCIGFTMGINGEYDQVAYYGRGPGENYADS
QQANIIDIWRSTVDAIFENYPFPQNNGNRQHVRWTALTNRHGNGLLVVPQRPINFSAWHYTQENIHAAQHCNELQRSDDI
TLNLDHQLLGLGSNSWGSEVLDSWRVWFRDFSYGFTLLPVSGGEATAQSLASYEFGAGFFSTNLHSENKQ
>SEQF1516_EDU85985.1 intracellular peptidase, PfpI family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVKGKKGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYL
RGDNRFVTFTRDFVNSGKPVFAICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLP
AFNREALRLLGA
>SEQF1516_EDU85986.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIWQPEFTDKTLSRKTGAVQGDVIKVNFGFINGQKFTTRNAMPDGFTPVDFDITYDCGDTSKIKNSLQMRIDGTTGVVDQ
YNLVARRRSSDNAPDVGIRIENLGGGVANIPFQNGILPVDPSGHGTVNMRAWPVNLVGGELETGKFQGTATITVIVR
>SEQF1516_EDU85987.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLRQLAWSGAVLLLVGTLLLAWSAVRQQESTLAIRAVHQGTTMPDGFSIWHHLDAHGIPFKSITPKNDTLLITFDSSDQ
SAAAKAVLDRTLPQGYIIAQQDNNSQAMQWLTRLRDNSHRFG
>SEQF1516_EDU85988.1 hexuronate transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAM
FAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVM
HSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAE
PAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIG
LFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSPLFAVLAVF
DLLGALVIWTVLQNKPAIEVAQETHNDPAPQH
>SEQF1516_EDU85989.1 preprotein translocase, SecG subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLATLFFIISLVLGNINSNKTNK
GSEWENLSAPAKTEQTQPAAPAKPTSDIPN
>SEQF1516_EDU85990.1 galactarate permease GarP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILDTVDEKKKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEVAKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKF
GSKKVYTYSLFFWSLFTFLQGFVDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFS
LALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISENGAVVDMDHKKPGSAAASGPKL
HYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIYLVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSL
TLARKLPIVLGMLLASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGNVASIVTPL
VIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK
>SEQF1516_EDU85991.1 putrescine aminotransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQ
GQEFIDCLGGFGIFNVGHRNPVVVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKL
AKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAMRTALNECKKTGDDVAAVILEPI
QGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFS
VLFDNPFLHTTTFGGNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMAIEFVDNEI
GYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALAAMRVSVEEA
>SEQF1516_EDU85992.1 putative inner membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAYWLAQGVGVIAFLIGITTFFNRDERRFKKQLSVYSAVIGVHFFLLGTYPAGASAILNAIRTLITLRTRSLWVMAIFI
VLTGGIGLAKFHHPVELLPVIGTIVSTWALFRCKGLTMRCVMWFSTCCWVIHNFWAGSIGGTMIEGSFLLMNGLNIIRFW
RMQKRGIDPFKVEKTPPAIDERG
>SEQF1516_EDU85993.1 aerotaxis receptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGFTLQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWS
GIVKNRRKNGDHYWVRANAVPMVREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTGKRIHKGLVVRKGWLGKLPSLP
LRWRARGVMTLMFILLAAMLWFVAAPVVTYILCALVVLLASACFEWQIVRPIENVARQALKVATGERNSVEHLNRSDELG
LTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAKGTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLS
ITASNAAVQGGEAMTTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGEVRHLASRS
ANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQISHSTLEQADGLSSLTRAVDELNLITQKNAEL
VEESAQVSAMVKHRASRLEDAVTVLH
>SEQF1516_EDU85994.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHLITQKALKDAAEKYPQHKTELVALGNTIAKGYFKKPESLKAVFPSLDNFKYLDKHYVFNVGGNELRVVAMVFFESQKC
YIREVMTHKEYDFFTAVHRTKGKK
>SEQF1516_EDU85995.1 phosphoglucosamine mutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRKIIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMP
TPAVAYLTRTFRAEAGIVISASHNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIE
FCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVGATDVRALQARVLAEKADLGIAF
DGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQLRGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGW
RIGAENSGHVILLDKTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVKAVTAEVET
ALGSRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV
>SEQF1516_EDU85996.1 dihydropteroate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHANLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIP
VVEAIAQRFEVWISVDTSKPEVIRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE
VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGMSRKSMIGQLLNVGPSERLSGSL
ACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAKENKRYE
>SEQF1516_EDU85997.1 cold-shock DEAD box protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVL
APTRELAVQVAEAMTDFSKHMRGVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADE
MLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRPDISQSYWTVWGMRKNEALVRFL
EAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALNGDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNY
DIPMDSESYVHRIGRTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQQQLESSDL
DQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKREFRDRDDRGPRDRNDRGPRGDREDRPRRER
RDVGDMQLYRIEVGRDDGVEVRHIVGAIANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLL
GDAQPHTGGERRGGGRGFSGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRRFGGDA
>SEQF1516_EDU85998.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFPVSSIGNDISSDLVRRKMNDLPESPTGNNLEALAPGIEKLKQTSIEMVTLLNTLQPSGKCIITGDFQKELAYLQNVIL
YNDSSLRLDFLGYNAQIIQRSDNTCELTINEPLKNQEISTGNININCPLKDIYNEFRRLNVIFSCGTGDIVDLSSLDLRN
VDLDYYDFTDKHMANTILNPFKLNSTNFTNANMFQVNFVSSTQNAKISWDYLLKITPVLTSISDMYSEEKIKFVESCLNE
LGDITEEQLKIMRFAIIKSIPRATLTDKLENDLTKEIYKSSSKINNCLNRIKLPEMIDFSSEKIHNYIDIIIEDYENIKE
NAYLVIPQINYTMDLNIEDSSSEELFSDNTLEKDENSPDNGFEVGEYNTYEAYNSENQYFTRENYTYNYDLLNAI
>SEQF1516_EDU85999.1 peptidase, U32 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYSLGPVLWYWPKETLEDFYQQAATSSADVIYLGEAVCSKRRATKVGDWLEMAKSLAGSGKQIVLSTLALVQASSELGE
LKRYVENGEFLIEASDLGVVNMCAERKLPFVAGHALNCYNAVTLKILLKQGMMRWCMPVELSRDWLVNLLNQCDELGIRN
QFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRNVLSQENQQVFVLNGIQTMSGYVYNLGNELASMQGL
VDVVRLSPQGTDTFAMLDAFRANENGAAPLPLTANSDCNGYWRRLAGLELQA
>SEQF1516_EDU86000.1 monooxygenase, luciferase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDKTIAFSLLDLAPIPEGSSARDAFSHSLDLARLAEKRGYHRYWLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGG
VMLPNHSPLVIAEQFGTLNTLYPGRIDLGLGRAPGSDQRTMMALRRHMSGDIDNFPRDVAELVAWFDARDPNPHVRPVPG
YGEQIPVWLLGSSLYSAQLAAQLGLPFAFASHFAPDMLFQALHLYRSNFKPSARLEKPYAMVCINIIAADSNRDAEFLFT
SMQQAFVKLRRGETGQLPPPIQNMDQFWSPSEQYGVQQALSMSLVGDKAKARHGLQSILRETDADEIMVNGQIFDHQARL
HSFELAMDVKEELLG
>SEQF1516_EDU86001.1 putative permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWQPYYGKAFTAAETHSIGKSILAQADANPWQAALDYAMIYFLAVWKA
AVLGVILGSLIQVLIPRDWLLRTLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPVLNPAT
LVFMGFVLGWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFSRWGRALWTLFWSTIPVYILAVL
VLGAARVWLFPHADGAVDNSLMWVVAMAVAGCLFVIPTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAF
PAKALWLTGAMVAVSGVIVGGLALLF
>SEQF1516_EDU86002.1 formate acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGDESFLAEATPATTELWEKVMEGIRIENATHAPVDFDT
NIATTITAHDAGYINQPLEKIVGLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPD
MLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDLEATIRLREELAEHRHALLQIQE
MAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNGGAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMV
RFLRTPEFDSLFSGDPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYAAQVSIVTS
SLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYAINGGVDEKLKIQVGPKTAPLMDDVLDYDKV
MDSLDHFMDWLAVQYISALNIIHYMHDKYSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDKNGLAV
DFEIDGEYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNTPDGRRAGTPFAPGANP
MHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKEDPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREML
LDAIEHPEKYPNLTIRVSGYAVRFNALTREQQQDVISRTFTQAL
>SEQF1516_EDU86003.1 ribosome-binding factor A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMSRDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIR
SLLGKAMRLRIVPELTFFYDNSLVEGMRMSNLVTSVVKHDEERRVNPDDSKED
>SEQF1516_EDU86004.1 2-dehydro-3-deoxyglucarate aldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWLVLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNE
PVIIKRLLDIGFYNFLIPFVETKEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDN
VDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAPVEADARRYLEWGATFVAVGSDL
GVFRSATQKLADTFKK
>SEQF1516_EDU86005.1 PTS system, D-galactosamine-specific, IID component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGSEISKKDITRLGFRSSLLQASFNYERMQAGGFTWAMLPILKKIYKDDKPGLSAAMKDNLEFINTHPNLVGFLMGLLIS
MEEKGENRDTIKGLKVALFGPIAGIGDAIFWFTLLPIMAGICSSFASQGNLLGPILFFAVYLLIFFLRVGWTHVGYSVGV
KAIDKVRENSQMIARSATILGITVIGGLIASYVHINVVTSFAIDSTHSVALQQDFFDKVFPNILPMAYTLLMYYFLRVKK
AHPVLLIGVTFVLSIVCSAFGIL
>SEQF1516_EDU86006.1 evolved beta-galactosidase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIIDNLEQFRQIYASGKKWQRCVEAIENIDNIQPGVAHSIGDSLTYRVETDSATDALFTGHRRYFEVHYYLQGQQKIEY
APKETLQVVEYYRDETDREYLKGCGETVEVDEGQIVICDIHEAYRFICNNAVKKVVLKVTIEDGYFHNK
>SEQF1516_EDU86007.1 2,4-dienoyl-CoA reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYPSLFAPLDLGFTTLKNRVLMGSMHTGLEEYPDGAERLAAFYAERARHGVALIVSGGIAPDLTGVGMEGGAMLNDASQ
IPHHRTITEAVHQEGGKIALQILHTGRYSYQPHLVAPSALQAPINRFVPHELTHEEILQLIDDFARCAQLAREAGYDGVE
VMGSEGYLINEFLTLRTNQRSDQWGGDYHNRMRFAVEVVSAVRERVGNDFIIIYRLSMLDLVEGGGTFAETVELAQAIEA
AGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAEL
LSKAQSGRADEINTCIGCNQACLDQIFVGKVTSCLVNPRACHETKMPILPAMQKKNLAVVGAGPAGLAFAINAAARGHQV
TLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYRRMIEVTGVTLKLNHTVTADQLQAFDETILASGIVPRTPPIDGIDHPK
VLSYLDVLRDKAPVGNKVAIIGCGGIGFDTAMYLSQPGESTSQNIAGFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIVM
LQRKASKPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKIDDDGLHVVINGETQVLAVDNVVICAGQEPNRALAQPLIDS
GKTVHLIGGCDVAMELDARRAIAQGTRLALEI
>SEQF1516_EDU86008.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATVPTRSGSPRQLTTKQTGDAWEVQARRWLEGKGLRFVAANVNERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASV
TRSKQHKLLQTARLWLARHNGSFDTVDCRFDVVAFTGNEVEWIKDTFNDHS
>SEQF1516_EDU86009.1 L-serine ammonia-lyase TdcG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSHIVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVI
DEIPAFIELVTRSGRLPVASGAHIVDFPVAKNIIFHPEMLPRHENGMRITAWKAQEELLSKTYYSVGGGFIVEEEHFGLS
HDVETPVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHDGIERGMNTEGVLPGPLNVPRRA
VALRRQLVSSDNISNDPMNVIDWINMYALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAG
AIGALYKMNASISGAEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCEPVAGQVQIPCIERNAINA
VKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>SEQF1516_EDU86010.1 protein Alx [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTVGTPLLWGGFAVVVAIMLAIDLLLQGRRGAHAMTMKQAAAWSLVWVTLSLLFNAAFWWYLVQTEGRAVADPQALAFL
TGYLIEKSLAVDNVFVWLMLFSYFSVPAALQRRVLVYGVLGAIVLRTIMIFTGSWLISQFDWILYIFGAFLLFTGVKMAL
AHEDESGIGDKPLVRWLRGHLRMTDTIDNEHFFVRKNGLLYATPLMLVLILVELSDVIFAVDSIPAIFAVTTDPFIVLTS
NLFAILGLRAMYFLLAGVAERFSMLKYGLAVILVFIGIKMLIVDFYHIPIAVSLGVVFGILVMTFIINAWVNYRHDKQRV
G
>SEQF1516_EDU86011.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAEQALKQSRYRLGETGDAIAKQTRVAAARADEYVRENP
WTGVGIGAAIGVVLGVLLSRR
>SEQF1516_EDU86012.1 putative inner membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQWYLSVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLILGLELPYLSMLYLLATFLPVLALAIRRLHDTDRSGAW
ALLFFVPFIGWLVLLVFFCTEGTSGSNRYGNDPKFGSN
>SEQF1516_EDU86013.1 tetrapyrrole methylase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAEDTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAK
LQEGQNIALVSDAGTPLINDPGYHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIE
AEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVKEDENRRKGEMVLIVEGHKAQEE
DLPADALRTLALLQAELPLKKAAALAAEIHGVKKNALYKYALEQQG
>SEQF1516_EDU86014.1 phospholipid-binding domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKALSPIAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQVDDGTLEVRVNSALSKDEQIKKEARINVTAYQGKVL
LVGQSPNAELSARAKQIAMGVDGANEVYNEIRQGQPIGLGEASNDTWITTKVRSQLLTSDLVKSSNVKVTTENGEVFLMG
LVTEREAKAAADIASRVSGVKRVTTAFTFIK
>SEQF1516_EDU86015.1 translation initiation factor IF-2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQTLIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKS
VQIEVRKKRTFVKRDPQEAERLAAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSN
QQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDNAEPTEDSSDYHVTTSQHARQAE
DESDREVEGGRGRGRNAKAARPKKGNKHAESKADREEARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGE
LANKMAVKGSQVIKAMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAPVVTIMGHV
DHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTI
EAIQHAKAAQVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAV
RKGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSIPVEILGLSGVPAAGDE
VTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMTEGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKI
IGSGVGGITETDATLAAASNAILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLAEV
RDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVRNGMECGIGVKNYNDVRTGDVIEVF
EIIEIQRTIA
>SEQF1516_EDU86016.1 putative SanA protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRAFARLLLRICFSRRTLKIACLLLLVAGATIFIADRVMVNASKQLTWSDVNVVPARNVGLLLGARPGNRYFTRRIDTA
AELYHAGKVKWLLVSGDNGRKNYDEASGMQQALIAKGVPAKVIFCDYAGFSTLDSVVRANKVFGENHITIISQEFHNQRA
IWLAKQYGIDAIGFNAPDLEKGRGKIVRLREKLARVSAVIDAKIFNRQPKYLGPSVIIGPFSEHGCPAQK
>SEQF1516_EDU86017.1 2-hydroxy-3-oxopropionate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAAGAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGI
IEGAKPGTVLIDMSSIAPLASREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHT
GEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDL
ANALDTSHGVGAQLPLTAAVMEMMQALRADGLGTADHSALACYYEKLAKVEVTR
>SEQF1516_EDU86018.1 PTS system, N-acetylgalactosamine-specific, IIC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEISLLQAFALGIIAFIAGLDMFNGLTHMHRPVVLGPLVGLVLGDLHTGILTGGTLELVWMGLAPLAGAQPPNVIIGTIV
GTAFAITTGVKPDVAVGVAVPFAVAVQMGITFLFSVMSGVMSRCDRMAENADTRGIERVNYLALLALGTFYFLCAFLPIY
FGAEHAKTIIDVLPQRLIDGLGVAGGIMPAIGFAVLLKIMMKNVYIPYFILGFVAAAWLKLPVLAIAAAALAMALIDLLR
KSPEPTQPAAQKEEFEDGI
>SEQF1516_EDU86019.1 methyltransferase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEIRGPVLILNDAFGALSCALAEHKPYSIGDSYISELAT
RENLRLNGIDESSVKFLDSTADYPQQPGVVLIKVPKTLALLEQQLRALRKVVTPQTRIIAGAKARDIHTSTLELFEKVLG
PTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGARFFMQHLPENLEGEIVDLGCGNG
VIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNMPEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAW
EMFHHARRCLKINGELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR
>SEQF1516_EDU86020.1 transcriptional regulator, DeoR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVSTVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEP
SVEDKSALNTAMKRSVAKAAVELIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLR
RQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERIIVVTDSSKFNRSSLHKIIDTQRI
DMIIVDEGIPADSLEGLRKAGVEVILVGE
>SEQF1516_EDU86021.1 lipoprotein NlpI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRAL
ARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDD
PNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMERLKADATDNTSLAEHLSETNFYL
GKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALLELSLLGQDQDDLAESDQQ
>SEQF1516_EDU86022.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEYPVHFHLLNTFAFSCSPLSALFYKKHTKLFLSPIKDD
>SEQF1516_EDU86023.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGVGLSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSEDGINVDDCADVSHQVSAVLDVEDPITVAYNLEV
SSPGLDRPLFTAEHYARFVGEEVTLVLRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF
>SEQF1516_EDU86024.1 glucuronate isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAEDYRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDAS
DREKFDAWAATVPHTIGNPLYHWTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDP
IDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADLQTALTKRLDHFAAHGCKVSDHA
LDVVMFAEANEAELDSILARRLAGETLSEHEVAQFKTAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDS
INDRPMAEELSKLLSKQNEENLLPKTILYCLNPRDNEVLGTMSGNFQGEGMPGKMQFGSGWWFNDQKDGMERQMTQLAQL
GLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLGEMVKNICFNNARDYFAIELN
>SEQF1516_EDU86025.1 threonine dehydratase operon activator protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTGITIFYGDNIIRYVVNTKKGLRPYFKQLPDNYQAKFELNLMSKFSNFIINKPFSAINNAARHIFSRYLLENKHLFYQY
FKISNTGIDHLEQLINVNFFSSDRTSFCECNRFP
>SEQF1516_EDU86026.1 helix-turn-helix DNA-binding domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIAIADILHAGEKLTAVAPFLAGIQNEEQYIQALELVDHLLLNDPENPLLDLVCAKITAWEESAPEFAEFNAMAQAMPGG
IAVIRTLMDQYGLTLSDLPEIGSKSMVSRVLSGKRKLTLEHAKKLATRFGISPALFID
>SEQF1516_EDU86027.1 putative methionyl-tRNA synthetase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METVAYADFARLEMRVGKIVEVKRHENADKLYIVQVDVGEKTLQTVTSLVPYYSEEELMGKTVVVLCNLQKAKMRGETSE
CMLLCAETDDGSESVLLTPERMMPAGVRIV
>SEQF1516_EDU86028.1 HtrA suppressor protein SohA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGQDSIHYEILPGGQVFMCRLGDEQEDHTMNAFLRFLDTDIQNN
PQKTRPFNIQQGKKLVAGMDVNIDDEIGDDE
>SEQF1516_EDU86029.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTGTGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEP
FISVSVVNPLMLENGWTFDDSFPGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAF
DALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVEKVFESLARLEQILGQHRYLTGNQLTEADI
RLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRDIYQMPGIAETVNFDHIRNHYFRSHKTINPTRIISIGPWQDLDEP
HGRDVRLG
>SEQF1516_EDU86030.1 transcriptional regulator TdcA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIINDIEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITRE
MKNMVNEISGMSSEAVVEVSFGFPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKL
QDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNGISIENIVKTDSVVTIYNLVLNA
DFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAVWSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG
>SEQF1516_EDU86031.1 transcription termination/antitermination factor NusA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEIDVRVQIDRKSGDFDTFRRWLVVDEVTQPTKEITLEAA
RYEDESLNLGDYVEDQIESVTFDRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNISLDLGNNAEA
VILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRSKPEMLIELFRIEVPEIGEEVIEIKAAARDPGSRAKIAVKT
NDKRIDPVGACVGMRGARVQAVSTELGGERIDIVLWDDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGR
NGQNVRLASQLSGWELNVMTVDDLQAKHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKELLEIEGLDE
PTVEALRERAKNALATIAQAQEESLGDNKPADDLLNLEGVDRDLAFKLAARGVCTLEDLAEQGIDDLADIEGLTDEKAGA
LIMAARNICWFGDEA
>SEQF1516_EDU86032.1 RNA polymerase sigma factor RpoD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDIIQMINDMGIQVMEEAPDADDLMLAENTADEDAAEAA
AQVLSSVESEIGRTTDPVRMYMREMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSD
LITGFVDPNAEEDLAPTATHVGSELSQEDLDDDEDEDEEDGDDDSADDDNSIDPELAREKFAELRAQYVVTRDTIKAKGR
SHAAAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVMMDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAI
AMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQ
FLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNRISRQMLQEMGREPTP
EELAERMLMPEDKIRKVLKIAKEPISMETPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLR
MRFGIDMNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD
>SEQF1516_EDU86033.1 putative endoribonuclease L-PSP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPADVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITD
LNDFATINEVYKQFFDEHQATYPTRSCVQVARLPKDVKLEIEAIAVRSA
>SEQF1516_EDU86034.1 propionate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSV
ALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
WKYYEELGVRRYGFHGTSHRYVSLRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSGDV
DFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDG
IIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRSNSFGERIVSSENARVICAVIPTNEEKMIALDAIHLGKVNAPAE
FA
>SEQF1516_EDU86035.1 threonine/serine transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRAGFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNP
SGNITETVEEHFGKTGGVVITFLYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLM
VKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIMVFSFNFSPIVSSFVVSKREEYE
KDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLFTLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAAS
IIALVAIFKSFFGHYLGTLEGLNGLVLKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAMGAPIIASL
LCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF
>SEQF1516_EDU86036.1 galactarate dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLELIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAI
PRGSWIDESMVVLPKAPPLHTLPLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL
LPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKLQPERLLTGTDDVQAIPVESASI
VSLQDEKHVGFQSMVEDILQVAERHLQKLNQRQRETCPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFS
EVTEVRDAIHLLTPRAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGKSAIVEVLS
PGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVPVIKMATRTELANRWFDLMDINAGTIATGEE
TIEEVGWKLFHFILDVASGKKKTFSDQWGLHNQLAVFNPAPVT
>SEQF1516_EDU86037.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKTILTPVTCALLISFSAHATNADNYKNVINRTGAPQYMKDYDYDDHQRFNPFFDLGAWHGHLLPDGPNTMGGFPGVA
LLTEEYINFMASNFDRLTVWQDGKKVNFTLEAYNIPGALVQKLTAKDVQVEMTLRFATPRTSLLETKIISNKPLDLVWDG
ELLEKLEAKEGKPLSDKTIAGEYPDYQRKISATRDGLKVTFGKVRATWDLLTSGESEYQVHKSLPVQTEINGNRFTSKAH
INGSTTLYTTYSHLLTSQEVSKEQMQIRDILARPAFYLTASQQRWEEYLKKGLTNPDATPEQTRVAVKAIETLNGNWRSP
GGAVKYNTVTPSVTGRWFSGNQTWPWDTWKQAFAMAHFNPDIAKENIRAVFSWQIQPGDSVRPQDVGFVPDLIAWNLSPE
RGGDGGNWNERNTKPSLAAWSVMEVYNVTQDKTWVAEMYPKLVAYHDWWLRNRDHNGNGVPEYGATRDKAHNTESGEMLF
TVKKGNKEETQSGLNNYARVVEKGQYDSLEIPAQVAASWESGRDDAAVFGFIDKEQLDKYVASGGKRSDWTVKFAENRSQ
DGTLLGYSLLQESVDQASYMYSDNHYLAEMATILGKPEEAKRYRQLAQQLADYINTCMFDPATQYFYDVRIEDKPLANGC
AGKPIVERGKGPEGWSPLFNGAATQANADAVVKVMLDPKEFNTFVPLGTAALTNPAFGADIYWRGRVWVDQFWFGLKGME
RYGYRDDALKLADTFFRHAKGLTADGPIQENYNPLTGAQQGAPNFSWSAAHFYMLYNDFFRKQ
>SEQF1516_EDU86038.1 polyribonucleotide nucleotidyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRR
EGRPSEGETLIARLIDRPIRPLFPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ
YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNE
ALNARVAALAEARLSDAYRITDKQERYAQVDVIKSETIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGRE
KDMIRGLDVRTGVLPRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGMVGSPKRRE
IGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAGIAMGLVKEGDNYVVLSD
ILGDEDHLGDMDFKVAGSRDGISALQMDIKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKI
NPDKIKDVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRVYTGKVTRIVDFGAFVA
IGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQGRIRLSIKEATEQSQPAAAPEAPAAEQGE
>SEQF1516_EDU86039.1 oxidoreductase, NAD binding [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRFAVIGTNWITHQFVEAAHESGKYKLTAVYSRSLEQAQHFANEFSVEHLFTSLEAMAESDAIDAVYIASPNALHFSQT
QLFLSHKIHVICEKPLASNLAEVDAAIACARENQVVLFEAFKTASLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
DGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAHGVVVMDYGDFSVTLQHSKVSDSVLASEI
QGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHINTMLYEAELFATLVDEHLVDHPGLAVSRITAKLLTEIRRQTGVI
FPADSVKL
>SEQF1516_EDU86040.1 threonine dehydratase, catabolic [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEIFLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVA
CSAGNHAQGVSLSCAMLGIDGKVVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIA
GQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAASFHSGEITTHRTTGTLADGCDV
SRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQRNKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRV
SQITGFVDA
>SEQF1516_EDU86041.1 inner membrane protein yhbX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVQRLLFFVLTILVVKRISSLPLRLLVAAPFVLLTAADMSISLYSWCTFGTTFNDGFAISVLQSDPDEVAKMLGMYSPYL
CAFAFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQFAYKDAKNKNAFSPYILASRFATYTPFFNLNYFALA
AKEHQRLLSIANTVPYFQLSVRDTGIDTYVLIVGESVRVDNMSLYGYTRSTTPQVEAQRKQIKLFNQAISGAPYTALSVP
LSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETVYVRGFDELLLPHLSQALQQNTQ
QKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDACYDNSIHYTDSLLGQVFELLKDRRASVMYFADHGLERDPTKKNVY
FHGGREASQQAYHVPMFIWYSPVLGDGVDRTTENNIFSTAYNNYLINAWMGVTKPEQPQTLEEVIVHYKGDSLVVDANHD
VFDYVMLRKEFTEDKQGNPTPEGQG
>SEQF1516_EDU86042.1 ribosomal protein S15 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFAEHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTR
LIERLGLRR
>SEQF1516_EDU86043.1 peptidase, U32 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTEKKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQRA
VDMAAQLGADALILADLAMLEYAAERYPHIERHVSVQASATNEEAINFYHRHFDVARVVLPRVLSIHQVKQLARVTPVPL
EVFAFGSLCIMSEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNEVLIDRYQDGENAGYPTLCKGRYLVDG
ERYHALEEPTSLNTLELLPELMAANIASVKIEGRQRSPAYVSQVAKVWRQAIDRCKADPQNFVPQSAWMETLGSMSEGTQ
TTLGAYHRKWQ
>SEQF1516_EDU86044.1 amino acid permease family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDTKRNTIGKFGLLSLTFAAVYSFNNVINNNIELGLASAPMFFLATIFYFIPFCLIIAEFVSLNKNSEAGVYAWVKSSL
GGRWAFITAYTYWFVNLFFFTSLLPRVIAYASYAFLGYEYIMTPVATTIISMVLFAFSTWVSTNGAKMLGPITSVTSTLM
LLLTLSYILLAGTALVGGVQPADPITVDAMIPNFNWAFLGVTTWIFMAAGGAESVAVYVNDVKGGSKSFVKVIILAGIFI
GVLYSVSSVLINVFVSSKELKFTGGSVQVFHGMAAYFGLPEALMNRFVGLVSFTAMFGSLLMWTATPVKIFFSEIPEGIF
GKKTVELNENGVPARAAWIQFLIVIPLMIIPMLGSNTVQDLMNTIINMTAAASMLPPLFIMLAYLNLRAKLDHLPRDFRM
GSRRTGIIVVSMLIAIFAVGFVASTFPTGANILTIIFYNVGGIVIFLGFAWWKYSKYIKGLTAEERHIEATPASNVD
>SEQF1516_EDU86045.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQKLEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEA
ADKLTTDAEALARGWETHLTIVTEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSS
EINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLDKQPRLTVSTIEDKRQALLAGLG
VATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWRRDSMGEAKSWCLREIPKLFNGK
>SEQF1516_EDU86046.1 IS629 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU86047.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAETRLAEDEATA
>SEQF1516_EDU86048.1 hypothetical protein ECH7EC4501_5458 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTARPDKAFAPHPAIPFASFIFSFNDHGFRFISFFSIELSVSFL
>SEQF1516_EDU86049.1 tRNA pseudouridine synthase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHTGALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIA
RLGQRTDTSDADGQIVEERPVTFSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLF
IRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEHLRELVEQAEQQDIPAAELLDPL
LMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAPLEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA
>SEQF1516_EDU86050.1 altronate dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQYIKIHALDNVAVALADLAEGTEVSVDNQTVRLRQDVARGHKFALTNIAKGANVIKYGLPIGYALADIAAGEHVHAHNT
RTNLSDLDQYRYQPDFQDLPAQAADREVQIYRRANGDVGVRNELWILPTVGCVNGIARQIQNRFLKETNNAEGTDGVFLF
SHTYGCSQLGDDHINTRTMLQNMVRHPNAGAVLVIGLGCENNQVAAFRETLGDIDPERVHFMICQQQDDEIEAGIEHLHQ
LYNVMRNDKREPGKLSELKFGLECGGSDGLSGITANPMLGRFSDYVIANGGTTVLTEVPEMFGAEQLLMDHCRDEATFEK
LVTMVNDFKQYFIAHDQPIYENPSPGNKAGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAPGNDAVATS
ALAGAGCHMVLFSTGRGTPYGGFVPTVKIATNSELAAKKKHWIDFDAGQLIHGKAMPQLLEEFIDTIVEFANGKQTCNER
NDFRELAIFKSGVTL
>SEQF1516_EDU86051.1 G/U mismatch-specific DNA glycosylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQAGFTDHQLKPQEAQHLLDYRCGVTKLVDRPTVQANEI
SKQELHAGGRKLIEKIEDYQPQALAILGKQAYEQGFSQRGAQWGKQTLSIGSTQIWVLPNPSGLSRVSLEKLVEAYRELD
QALVVRGR
>SEQF1516_EDU86052.1 siderophore-interacting protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNSPRYPQRVRNDLRFRELTVLRVERISAGFQRIVLGGEALDGFTSRGFDDHSKLFFPQPDAHFVPPTVTEEGIVWPEG
PRPPSRDYTPLYDELRHELAIDFFIHDGGVASGWAMQAQPGDKLTVAGPRGSLVVPEDYAYQLYVCDESGMPALRRRLET
LSKLAVKPQVSALVSVRDNACQDYLAHLDGFNIEWLAHDEQAVDARLAQMQIPADDYFIWITGEGKVVKNLSRRFEAEQY
DPQRVRAAAYWHAK
>SEQF1516_EDU86053.1 hypothetical protein ECH7EC4501_5441 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKGFPIAHIFHPSIPPMHAVVNNHNRNIDYWTVKRKFAEIVSTNDVNKIYSISNELRRVLSAITALNFYQGDVPSVMIRI
QPENMSPFIIDISTGEHDDYIIQTLDVGTFAPFGEKCTCSAVNKKELECIKETISKYCAKFTRKEAILTPPAYFNKTSIT
SDCWQILFFSPDHFNNDFY
>SEQF1516_EDU86054.1 hypothetical protein ECH7EC4501_5395 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWLSFAQYLMLFVNICCYFARFLSGMDLIIAAQMHAFRALTA
>SEQF1516_EDU86055.1 serine transporter family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMSIGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMY
LFQRLFINTLAESPECKDYPSVISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGL
VLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLVKNAIITLPFTLTSILFIQTLSP
MVISYRSREKSIEVARHKALRAMNIAFGILFIIVFFYAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVS
VILNIFAVMTAFFGVYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTSICSPIFGL
VGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS
>SEQF1516_EDU86056.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEEYDNAPNSCRLALTHFDDLFRHGDKVQFDDQGITVGQ
HLHIEMSRCRRWLSPTLQMTAVNFRLIAWQQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVIDKQNI
ASAVASMMGLGIGLTPSADDYLTGLALILFISGHPAGKYKEEFYLGLQRGRNNTTLLSAITLEAALQQRCRENIHRFIHN
IIYDIPGNATQAIEKIKHIGSSSGCDMLYGMADGCALSQTYGGNYVS
>SEQF1516_EDU86057.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQFEISYDDVVRLKHLRNVGEYVTGMAALQDCYEKPAGAQCEQLVSLIYLMTEQLDGVVQRCHDDLMNAEVA
>SEQF1516_EDU86058.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKNLILAFALFSLPVFAEEDLGPGKYVCDIRISSLDTATQILSKSATVLDNGNNFIVQMPNGDQLYSPDLENVDDGIKQ
KATIGGVTFIRRPTFNDRFIVEDGNTGFFYKMRNCEKK
>SEQF1516_EDU86059.1 cyanate transport protein CynX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLVLVLIGLNMRPLLTSVGPLLPQLRQASGMSFSVAALLTALPVVTMGGLALAGSWLHQHVSERRSVAISLLLIAVGAL
MRELYPQSALLLSSALLGGVGIGIIQAVMPSVIKRRFQQRTPLVMGLWSAALMGGGGLGAALTPWLVQHSETWYQTLAWW
ALPAVVALFAWWWQSTREVASSHKTTTIPVRVVFTPRAWTLGVYFGLINGGYASLIAWLPAFYIEIGASAQYSGSLLALM
TLGQAAGALLMPAMARHQDRRKLLMLALALQLVGFCGFIWLPLQLPVLWAMVCGLGLGGAFPLCLLLALDHSVQPAIAGK
LVAFMQGIGFIIAGLAPWFSGVLRSISGNYLMDWAFHALCVVGLMIITLRFAPARFPQLWVKEA
>SEQF1516_EDU86060.1 2-methylcitrate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHYRGYDILDLAEHCEFEEVAHLLIHGKLPTRDELAAYK
TKLKALRGLPANVRTVLEALPAASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
QPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSDMYSAIIGAIGALRGPKHGGANE
VSLEIQQRYETPDEAEADIRKRVESKEVVIGFGHPVYTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKM
FPNLDWFSAVSYNMMGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRQFVALDKRQ
>SEQF1516_EDU86061.1 ankyrin repeat protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAITLASLYQQYACVQALIDAGADINKQDHTCLNPFLISC
LNGDLTLLRIILPAKPDLNCVTRFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA
>SEQF1516_EDU86062.1 ribosomal protein L36 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKKKR
>SEQF1516_EDU86063.1 IS2 ORF2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDVMLGAIEKRFGDKVPEQSIQWLTDNGSAYRAHETRQFARELNLEPCTTAISSPQSNGIAERFVKTMKEDYIAFMPKP
NVRTALHNLAVAIEHYNENHPHSALGYRSPREYRRQRVTLT
>SEQF1516_EDU86064.1 methylisocitrate lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYLSGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSL
PLLVDADIGFGSSAFNVARTVKSMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATPLFTTDELRSAHVAMALYPLSAF
RAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYESINYYHYEEKLDDLFVRSQAK
>SEQF1516_EDU86065.1 bacterial FdrA protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNKGVLKNLGLLTPELEQAKNGDLMIVINGKSGADNEQL
LVEIEELFNTKAQSGSHEARYATIASAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQLIGTGGRDLSEKIGGLMMLDAI
GMLENDPQTEIIALISKPPAPAVARKVLERARACRKPVVVCFLGRGETPVDEQGLQFARGTKEAALKAVMLSGVKQEHLD
LHTLNQPLITDVRARLKPQQKYIRGLFCGGTLCDETMFAVMEKHSDVYSNIQPDPEFRLKDINRSIKHTFLDFGDDDFTN
GKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIEAIKEAKAIAAAEGRELIILAYVLGTDLDTPSL
EQQSQMLLDAGVILASSSTNTGLLAREFICKGEEA
>SEQF1516_EDU86066.1 putative polarity suppression protein encoded in CP-933I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMARVTPDQALISFRNARILWAGHSESRKAVEQQIESLLTAMEKPADYARQLELQREHLDVLKWQINCAARECIYSQHQL
MEACTEDALSNFMQANGAALTSALAPFLKGRGGVDVASRILRNALVRQLAITPPEIAGDYRMILDESGVMPDPMMVRDCQ
SSYTPAQQLRFQQRLDYINGMQE
>SEQF1516_EDU86067.1 protein ash [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVVRAGQPSGWPVSNKAGYANPVRAATSEIGVSGGSNNRYLLEAAIMATILTPSHPQYVFVFAAIRRADTHPRICMLRTV
SCDERSARRLLVRDYVLSLSARLPAGEVTL
>SEQF1516_EDU86068.1 putative tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPFARYFCIFINVGLGEAAKRDVGTGENQIPDMASFASGNGWMKLPNGKILQYGRGAVTPTLSTQTMRITFSIPFPKKAD
CAMLTHSGDGGAPLGAGRGFVMTAEGPTLTGFNSAYRTSSTSDTVSMNYSWWAVGE
>SEQF1516_EDU86069.1 IS629 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU86070.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQESVGLISVAHQAFVTIAGCGVNALSGLQVAQEFVGLISVAHQAFITIAGCGVNALSGLRMAQESVGLISVAHQAFVT
IAGCGVNALSGLRMAREL
>SEQF1516_EDU86071.1 putative homoserine/threonine efflux protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDPLHAVYLTVGLFVITFFNPGANLFVVVQTSLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVG
GAYLLWFAWCSMRRQSTPQMSTLQQPINAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTWARLMAWAGIVLAS
IIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYEGVTQR
>SEQF1516_EDU86072.1 LysR substrate binding domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKRENYNELYLFMQVVREGSFTAAAKRLGLAQSGVSRSVRELEERLGVQLLVRTTRKLSLTQAGEQLYQKTASGFEMLD
LGLATLAHYRETPSGTVRINASQHAIDKCLLPKLAVFKQRYPDIQLELINESRFVDIIEERFDAGVRLGPEVSQGMVAVR
ITPDMEMAIVGTPEHFRRYGFPQTPADLKAHPCIAYQFADGSVYQWELNQDDKKITHQPEGQWAFSDSYMEAEAARLGLG
LAYVPVELVADDLEHGKLIRVLQRYSLRMEGLFLYYPHRNVSPALRMVIDTLKI
>SEQF1516_EDU86073.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDNFFTFRKIKVTGFNKLDAIIEFGSKLTILYGGSDSGKTYIYYLIRYLLGSEKLKNKDIDHAQGYDLAYLEFNFQGRV
MTIERSLQDSAHYRLYDSSIENVSEANLLMVFSKSASSKKSFSSYFYGRLNFKEAKVRTNLSNTLHNEPPRVSWRVFYL
>SEQF1516_EDU86074.1 hypothetical protein ECH7EC4501_1461 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSEPGGNSAASIVGFGPVERDAEKCTTGTTRHAWIQIAHNSPVQL
>SEQF1516_EDU86075.1 lactose permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWII
TGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGI
MFTINNQFVFWLGSGCALILAILLFFAKTDAPSSATVANAVGANHSAFSLKLALELFRQPKLWFLSLYVIGVSCTYDVFD
QQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKT
LHMFEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGFTLISVFTL
SGPGPLSLLRRQVNEVA
>SEQF1516_EDU86076.1 mannitol-1-phosphate 5-dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDASRGASDSCAQMPDATLARLIMPTGLNRRSDKALAPHPTPCADA
>SEQF1516_EDU86077.1 clavaldehyde dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKENVMDKVILITGASSGIGEGIARELGMTGAKVLLGARRVERIEAIATEICRAGGIAKARELDVTDRQSMADFVQAALD
SWGRVDVLINNAGVMPLSPLAAGKQDEWALTIDVNIKGVLWGIGAVLPVMEAQGSGQIINLGSIGALSVVPTGAVYCASK
FAVRAISDGLRQESSKIRVTCVNPGVVESELASTITHVETMKAMDAYRSVALQPADIARAVRHIIESPESVDTTEITIRP
TASAN
>SEQF1516_EDU86078.1 hypothetical protein ECH7EC4501_1518 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITKRLFIISASLQGSQEVFAQISALERIRIFEYFYAE
>SEQF1516_EDU86079.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLHKKHVNEKSDWLMSNAINPRMAYFSLAAVLNLIEYGQDSD
>SEQF1516_EDU86080.1 hydrolase of the alpha/beta superfamily [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAFTRTLKTAMPVMLLFASLSGVTTMSYADSTNPNAPVSMTDKWDKTFAESQKVDHRKVSFPNRYGITLVGDLYLPKDR
GDRKLAAIAVSGPFGAVKEQSSGLYAQTLAERGFVTLAFDPSYTGESGGYPRNVASPDINTEDFSAAVDFLGLQKEVDRN
RIGLLGICGWGGMALNDAAMDTRVKAVATSVMYDMSRAMGHGVGDGEDRYSTADRRAVLQYLNEQRWKDAQSGTFAHGGH
DINVDSNGKVSAGERILPETLPANPHPVLKEFFDYYRMPRGFHERSVNSTGAWTATMPLSFMNMPLLSYASEITIPTLIV
TGEKAHSRYFAEDAYKAVGSKDKELVVVPGANHVDLYDNVAGKIPFAKFEQFFQTKLK
>SEQF1516_EDU86081.1 50S ribosomal protein L31 type B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPYVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRF
VSTKKGA
>SEQF1516_EDU86082.1 IS66 family element, transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQLDKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTL
TGRVYDPAVQRPLRQTRTRKPFPESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
DAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELRRSLLSGWVDACCRLLSPLEEALHGYVMT
DGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNAGSALAPAVWFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELY
RNGGITEAACWAHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWLREKMKT
LSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKNFLFFGSDHGGERGALLYSLIGTCKLNDVDP
ESYLRHVLGVIADWPVNRVSELLPWRIALPAE
>SEQF1516_EDU86083.1 putative activator encoded in prophage CP-933I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPRRNEQESEKAQMPEKQQQTLNRYGSASKLSSRQQIPV
>SEQF1516_EDU86084.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISLKAPHNNLMPYTQQSILNTVKNNQLPEDIKSSLVSCVDIFKVLIKQYYDYPYDCRDDLVDDDKLIHLMAAVRDCEWS
DDNALTINVQFNDFPGFYDWMDYPDHPVKFVFRILENQKGTVWVYDQDDAFLDIKANVQAGRFTGLKKLVQFINSVRTDC
KCILLEHHMPLLRLFPKGKECMHVEKWLREMSSIPETDAPIKQALAHGLLLHLKNIYPVFPESLVMLLLSVLDVKTYRDD
ARLNEGISNRVQELGDRYYPVNKHVKIRYTL
>SEQF1516_EDU86085.1 iron-sulfur cluster binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNQGEYPEDNRVGKHEPHDLSLTRRDLIKVSAATAAAAVVYPHSTLAASVPAATPAPEIMPLTLKVNGKTEQLEVDTRT
TLLDALRENLHLIGTKKGCDHGQCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFIKHDGFQCGY
CTSGQICSSVAVLKEIQDGIPSHVTVDLVSPPERTADEIRERMSGNICRCGAYANILAAIEDAAGEIKS
>SEQF1516_EDU86086.1 IS66 family element, orf2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPS
ARDGKVFLTQAQLAMLLEGIDWRQPKRLLTSLTML
>SEQF1516_EDU86087.1 oxidoreductase, zinc-binding dehydrogenase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKAVGSYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKHAP
GDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
ITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALGADEVVNSRNADEMAAHLKSFDF
ILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKSPEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIR
ADQINEAYERMLRGDVKYRFVIDNRTLTD
>SEQF1516_EDU86088.1 2-methylcitrate dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAQINNIRPEFDREIVDIVDYVMNYEISSKVAYDTAHYCLLDTLGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQ
FQLDPVQAAFNIGAMIRWLDFNDTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTGMIKAHEIQGCIAL
ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTGTRKSWAAGDATSRAVRLALMAK
TGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSYVMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKV
SIRTHEACIRIIDKKGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPVFTADYHDPEK
RAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQFPTRQQQRILEVSLDRARLEQMPVNEYLDL
YVI
>SEQF1516_EDU86089.1 FAD binding domain in molybdopterin dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAFTYERVNTPAEAALSAQRVPGAKFIAGGTNLLDLMKLEIETPTHLIDVNGLGLDKIEVTDAGGLRIGALVRNTDLVA
HERVRRDYAVLSRALLAGASGQLRNQATTAGNLLQRTRCPYFYDTNQPCNKRLPGSGCAALEGFSRQHAVVGVSEACIAT
HPSDMAVAMRLLDAVVETITPEGKTRSITLADFYHPPGKTPHIETALLPGELIVAVTLPPPLGGKHIYRKVRDRASYTFA
LVSVAAIIQPDGSGRVALGGVAHKPWRIEAADAQLSQGAQAVYDALFASAHPTAENTFKLLLAKRTLASVLAEARAQA
>SEQF1516_EDU86090.1 cytosine permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLGTGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLT
THLLARFSFGVKGSWLPSLLLGGTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSLIAVPA
IACLGGYSVWLAVNGMGGLDALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFGRNAKLAVLVAMVAFFLGNSLMF
IFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNIWTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNN
FVGWLTFLSAAIPPVGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGALSYLILNP
ILNRKTTAAMTHVEANSVE
>SEQF1516_EDU86091.1 cyanate hydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQQALPADAARQVGAKLDLDEDAILLLQMIPL
RGCIDDRIPTDPTMYRFYEMLQVYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF
>SEQF1516_EDU86092.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIDLNLLPIFIAVAEESNFSKAAARLGVTRSAVSQGIRRLEDAFGTMLVMRTTRSVNLTEAGERLHKSLSLPLSGIEAA
FEEMVSDHVPRGLLRIAVTSIAEEFLSGPLIASFAAANPAVTLDIVVTDEEFDIVAAGYDAGVRLGEVIEKDMIAVPLTG
RQREMVVASPSYLAANSTPVHPRELVNHKCIGWRQSPEVAPYRWPFEENGRAFDLAIEPQITTNDLRLMLRLALAGGGIT
IATQETFRPYIESGKLVSLLDDFLPQFPGFYLYFPQRRNIAPKLRALIDHVKEWRQQLA
>SEQF1516_EDU86093.1 cytosine deaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNNALQTIINARLPGKEGLWQIHLQDGKISAIDAQSGVMPITENSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSG
TLFEGIERWAERKALLTHDDVKQRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKLEVAPWIDLQIVAFPQEGI
LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDEIDDEQSRFVETVAALAHREGMG
ARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPW
YPLGTANMLQVLHMGLHVCQLMGYGQINDGLNLITHHSARTLNLQDYSIAAGNSANLIILPAENGFDALRRQVPVRYSVR
GGKVIASTQPAQTTVYLEQPEAIDYKR
>SEQF1516_EDU86094.1 2,5-diketo-D-gluconic acid reductase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKVKLNNGIEMPLLGFGVFQMTDAAECERAVIDAINTGYRLIDTAASYQNEPQVGNALKQSGIARNELFVTTKLWLQDT
SYEGAKAQFERSLNRLQLDYVDLYLIHQPYGDVHGAWRAMEELQQAGKIRAIGVSNFHPDRLADLIAFNNVVPAVNQVEV
NPFNQQLHAVPWMQSRGIQPEAWAPFAVTGR
>SEQF1516_EDU86095.1 beta-galactosidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTMITDSSAVVLQRRDRENPGVTQVNRLAAHPPFASWRNSEEARTNRPSQQLRSLNGEWQFVWFPAPEAVPESWLECDLP
DADTVVVPSNWQMHGYDAPIYTNVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
GYGQDSRLLSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHKPTTQISDFHVATLFNDDFSRAV
LEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFGGEIIDERGGYADRVTLGLNVENPKLWSAEIPNIYRAVVELHTAD
GTLIEAEACDVGFREVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSHYPNHPLWY
TLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRNHPSVIIWSLGNESGHGANHDALYRWIKSVD
PSRPVQYEGGGADTSATDIICPMYARVDEDQPFPAVPKWSIKKWLSLPGEMRPLILCEYAHAMGNSLGGFAKYWQAFRQY
PRLQGGFVWDLVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQQQFFQFRLSGRTIEVT
SEYLFRHSDNELLHWTVALDGKPLASGEVPLDVAPQGKQVIELPELPRLESTGQLWLTVHVVQPNATAWSEAGHISAWQQ
WRLAENLSVTLPSAPHAIPQLTTSETDFCIELDNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSEAT
RIDPNAWVERWKAAGHYQAEAALLQCTADTLADAVLITTVHAWQHQGKTLFISRKTYRIDGSGQMAITVDVEVASDTPHP
ARIGLTCQLAQVAERVNWLGLGPQENYPDRLTAACFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNI
SRYSQQQLMETSHRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK
>SEQF1516_EDU86096.1 putative invasin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRYKTGHKQPRFRYSVLARCVAWANISVQVLFPLAVTFTPVMAARAQHAVQPRLSMGNTTVTADNNVEKNVASFAANAG
TFLSSQPDSDATRNFITGMATAKANQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
RTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRASGWKKSPDIEDYQERPANGWDI
RAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQKDPHAISAEVTYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIG
EPLAKQLDTDSIRERRVLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTLSLGLVVSKATHGLKNVQWEAPS
LLAEGGKITGQGSQWQVTLPAYRPGKDNYYAISAVAYDNKGNTSKRVQTEVVITGAGMSADRTALTLDGQSRIQMLANGN
EQKPLVLSLRDAEGQPVTGMKDQIKTELTFKPAGNIVTRSLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITV
SVDGMSKTVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLRFVPQDTNGVTVGAISE
IKPGVYSAAVSSTRAGNVVVRAFSEQYQLVTLQQTLKFVAGPLDAAHSSITLNPDKPVVGGTVTAIWTVKDAYDNPVTSL
TPEAPSLAGAAAEGSTASGWTNNGDGTWTAQITLGSTAGELEVMPKLNGQNAAANAAKVTVVADALSSNQSKVSVAEDHV
KAGESTTVTLVAKDAHGNAISGLALSASLTGTASEGATVSSWTEKGNGSYVATLTTGGKTGELRVMPLFNGQPAATEAAQ
LTVIAGEMSSANSTLVADNKAPTVKTTTELTFTVKDAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVSTL
TLGSAAGQLSVMPRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITLTVVDTYGNPLQGQEVTLTLP
QGVTSKTGNTVTTNAAGKADIELMSTVAGEHNISASVNGAQKTVTVKFNADASTGQANLQVDAAAQKVANGKDAFTLTAN
VEDKNGNPVPGSLVTFNLPRGVKPLTGDNVWVKANDEGKAELQVVSVTAGTYEITASAGNSQPSNTQTITFVADKATATV
SGIEVIGNYALADGNAKQTYKVTVTDANNNLLKDSEVTLTASPANLVLTPNGTAKTNEQGQAIFTATTTVAAKYTLTAKV
SQADGQESTKTAESKFVADDTNAVLTASSDVTSLVADGISTAKLEVTLMSANNPVGGNMWVDIKTPEGVTEKDYQFLPSK
NDHFVSGKITRTFSTSKPGVYTFTFNALTYGGYEMKPVTVTITAVDADTAKGEEAMN
>SEQF1516_EDU86097.1 DNA-invertase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIGYVRVSTNDQNTDLQRNALNCAGCELIFEDKISGTKSERPGLKKLLRTLSAGDTLVVWKLDRLGRSMRHLVILVEEL
RERGVNFRSLTDAIDTSTPMGRFFFHVMGALAEMERELIVERTKAGLEAARAQGRIGGRRPKLTPEQWAQAGRLIAAGIP
RQKVAIIYDVGVSTLYKKFPAGDK
>SEQF1516_EDU86098.1 betaine aldehyde dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGREDVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILR
ERNDELAKLETLDTGKAYSETSTVDIVTGADVLEYYAGLIPSLEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTEHPGIAKVSFTGGVASGKKVMAN
SAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMMANFFSSGQVCTNGTRVFVPAKCNAAFEQKILARVERIRAGDVFD
PQTNFGPLVSFPHRDNVLRYIAKGKEEGARVLCGGDVLKGDGLDNGAWVAPTVFTDCSDEMTIVREEIFGPVMSILTYES
EDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQ
VEMAKFQSIF
>SEQF1516_EDU86099.1 fimbrillin MatA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTWQNDYSRDYEVENHMECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKDFVFINLNTDSLTEFINRDNE
WLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAGLSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGM
LPKSIARIENCSVKTVYTHRRNAEAKLYSKLYKLVQ
>SEQF1516_EDU86100.1 propionate--CoA ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFARWFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEE
ERTFTFRQLHDEVNAVASMLRSLGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQHIGARVPVAWLESNETSCILYT
SGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGVFFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWK
IVEKYQVSRMFSAPTAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESGWPIMAIAR
GLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGCIQTIWGDDDRFVKTYWSLFSRPVYATFDWG
IRDADGYHFILGRTDDVINVAGHRLGTREIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEK
AIMALVDSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLNQIRQAMEE
>SEQF1516_EDU86101.1 bacteriophage P4 DNA primase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGMKVSQAEKAARGHWSRILPALGVNVLKNRHQPCPVCAGKDRFRFDDQEGRGTWFCNQCGAGDGLALVSKVLDVGISE
AADRINGIIGNLLPVSQGMLESGSPEKEDGRKAAAVLAARLFDKSRQTTGNAYLTSKGFPALPCRELTAMHKVGGVAFRA
GDLVVPLYADGELVNLQLINANGGKCFLKGGQVKNAFYLVEGTAKAAKRLWIAEGYATALTINYLTGDAVMVAFSSVNFL
SLASIACSEYPTHQIIIAADRDLNGAGQTRGAAVTGACNCTMALPPVFGDWNDAFTQNGEEATRHAIHEVIKPAVASPFD
TMSEAEFTALSVSEKAQRVVDHYKNSLAVDPNGQLLSRYEAGAWKVIYYADFARDVAALFQRLDAPFSSAKIASLVETLK
LIVPQQQNPARQLIGFRNGVLDTRTGLFSPHDKKHWLRTLCEVDYTQPVDGESLETHAPAFWRWLDRAAGFNPEKRDIIL
AALFMVLANRYDWQLFLEVTGPGGSGKSILAEIATMLAGEDNATSATIEMLESPRERAALIGFSLIRLPDQEKWSGDGAG
LKAITGGDAVSVDPKYQNAYSTHIPAVILAVNNNPMRFTDRSGGVSRRRVILHFPDQIAPEERDTQLKEKIASELAVIVR
QLMQRFSDPMSARTLLQSQQNSDEALTIKRDADSAFDFCGYLEVLPDTTGMFMGNANIVPRQPRTYLYHAYLVYMEANGY
KNTLSLTMFGKGLPLMLKEYGLQYEKRRTNQGMQTNLALREESNADWLPKCDEFAAK
>SEQF1516_EDU86102.1 putative xanthine dehydrogenase accessory factor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYPLFDKDEHWHKPEQAFLTDDHRTILRFAVEALMSGKGAGLVTLVEIRGGAARPLGAQMVVREDGRYCGFVSGGCVEA
AAAFEALEMMGSGCDREIRYGEGSPWFDIVLPCGGGITLTLHKLRSAQPLLAVLNRLEQRKPAGLRYDPQAQSLVCLPTQ
TRTGWNLNGFEVGFRPCVRLMIYGRSLEAQATASLAAATGYDSHIFDLFPASASAQIDTDTAVILLCHDLNRELPVLQAA
REAKPFYLGALGSYRTHTLRLQKLHELGWSREETAQIRAPVGIFPKARNAHTLALSVLAEVASVRLHQEEDSCLPPSS
>SEQF1516_EDU86103.1 galactoside O-acetyltransferase LacA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMSMTERIKAGKLFTDMCEGLPEKRLRRKTLMYEFNHSHPSEVDKRESLIKEMFATVGENAWVEPPVYFSYGSNIHIGR
NFYANFNLTIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGA
GSIVTKDIPPNVVAAGVPCRVIREINDRDKQYYFRDYKVESSV
>SEQF1516_EDU86104.1 hypothetical protein ECH7EC4501_1487 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKSTIIFGIRNPFKNGYIPYTYSELLIQGLLRYTLMVYKKITDNNHVSSNSRDFI
>SEQF1516_EDU86105.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDITEFPSGVIEHLGWYVYRLIDPRDGSTFYVGKGKGNRVFAHMRGEVAAADDDDLLSNKLKQIREIRLAGLEVIHVIHR
HGMTDEKTAYEVEAALIDAYPGLTNIMNGAGSNEFGAAHVKELIATYQPETITFHHKALMISVNRSAKDSELYDAVRFSW
RINVSRASKAEVILATVRGIVRGVFIADKWLKSTREHFPTMKYWDEDPDFEATQSSRYGFEGREAPPEIANLYLGKKIPD
ELRKKGAMSPVRYSPNF
>SEQF1516_EDU86106.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITNQTEMVKSSNSYLIRFLTPLNSLKRMHILNISEMNSLLPLLIEMEG
>SEQF1516_EDU86107.1 putative AraC-type regulatory protein encoded in prophage CP-933H [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATTCSVILILESFDVYFGKESVFLERGSSVLVDSSSRDFFLTYPERVIVADFGAEFISRYLKANNLRDISDCREYPSYL
KINFADFSLIKGLISWANHCAEYIEIFDESIAFTCLSAFSSEKQFGVFLFGCLKSTGAKVKTIIHTDLSAPWRLKDISSR
LYLSESLLKRKLKEEGVSFSKIILDERMQMAEYLLSTRCYPISKVAKVCGYASVSYFTYVFRRYFGVSPSQYSQRSSESK
ILTHQGI
>SEQF1516_EDU86108.1 carbamate kinase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASDYDIVLTHGNGPQVGLDLRRAEIAHEREGLPLTPLAN
CVADTQGGIGYLIQQALNNRLARHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGAFFSESQRDELQKANPDWRFVEDAGRG
YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTDAGDYQSVDAVIDKDLSTALLAREIHADILVITTGVEK
VCIHFGKPEKQALDRVDIATMTRYMQEGHFPPGSMLPKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT
>SEQF1516_EDU86109.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIISKMLVGALAFAVTNVYAAELMTKAEFEKVESQYEKIGDISTSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNK
IHGTADIYKKK
>SEQF1516_EDU86110.1 iron-sulfur cluster binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDELGLWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQN
GGHVYFAKTKEDATRYILQVAQRKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQEPPSHVVVPAIHK
DRHQIRRVLHERLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCLVTNEGNARMCTTLPKTHIAVMG
MERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTGPREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMN
TCPAYRHIGGHGYGSIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDNVCPVRIPLSKLILRHRRVMAEKGITAKAEQ
RAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEARDLPEADGESFRSWFKKHQAQEKKNG
>SEQF1516_EDU86111.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVNLLIAMIIFALIWPVTALRAAVSKTTWADAPAREFVFVENNSDDNFFVTPGGALDPRLTGANRWTGLKYNGSGTIYQ
QSLGYIDNGYNTGLYTNWKFDMWLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDTSGFYGATVTSGGAKWMHGMLS
DAFYQYLQQMPVGSSFTMTINACQTSVNYDASSGARCKDQASGNWYVRNVTHTKAANLRLINTHSLAEVFINSDGVPTLG
EGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSIHIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEM
KSADSIYVFFSSNFFKQMVNQGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYTQTPSREGY
VGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGKAKVPFPATLSFITRNGATKTYDAGCDDSWR
DMTDALWLTTPWTDISGEVGQMDKTTVKFSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN
>SEQF1516_EDU86112.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQFDWTPPGQGNMQVVQALDNIADSPLADKIAAANQQALERIIQSHPVL
IGFDQAINVVPGMTPKTILHAGPPITWEKMCGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGVTSAS
MFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPILRDAMKIIGEIDLRLMLAQALHMGDECHNR
NNAGTTLLIQALTPGIIQAGYSVAQQREVFEFVASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSG
LPGQWFTGPAQQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSRQMREITLGENPN
VTIPLLGFMGVPSAVDITRVGSSGILPVINTAIAHKDAGVGMIGAGIVHPPFACFEKAILGWCERYGV
>SEQF1516_EDU86113.1 putative capsid morphogenesis protein encoded in CP-933I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIPEQNNNPIVEISIPVSTQQALEKVNATKSAWLEARRQQKAAADNIATIRQRRAEMEATTNALNEEWRTLFRESQGVV
SKEMKKLRTEIALGRETLEDFDELLAAQESENALLPQEAAELAGKYIHAHDTLVGIRAKQIWEDFMQSHGKALIQTLSLL
KSTMGREASAVVGVVHSVNDPDTLLKDFIHKHITRPALTNDAMPEQDPVFKLAGVAPDYAARLDFSNKLSPAAMHKMKVR
QERAEKEKAV
>SEQF1516_EDU86114.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQAFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIW
LDDGQLRIRKIQLEESEDNASVSEQTRQQLMALANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
IGQSSVNTLSSNLSYNFGIYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIGSGQQDSELYKAMYERDFAGHRF
AGGTLDTWNLQSLGPMTAISAGKIYGLSWGNQASSTIFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDT
RGLPYGIYDVEVEVIVNGRVISKRTQRVNKLFSRGRGVGAPLAWQVWGGSFHMDRWSENGKKTRPAKESWLAGASTSGSL
STLSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSSIGSISATLPGGFSSLWVNQEKTRIGNQLRRSDAD
NRAIGGTLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQNVYSGTFGSLGLRAGIQRYNNGDSNANTGKYIALDLSLP
LGNWFSAGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYVN
TNLTANGSVGWQGKNIAASGRTDGNAGVIFNTGLEDDGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSY
DIVSGRKSHLTLYPGNVAVIEPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYSGN
KTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES
>SEQF1516_EDU86115.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRRRGVTLTKALLTAVCMLAAPLTQAISVGNLTFSLPSETDFVSKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDG
ELLFAPRQLALQAGESEYFKFYYHGPQDNRERYYRVSFREVPTRNLTKRSPTGGEVSTEPVVVMDTILVVRPRQVQFKWS
FDQVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPEDVVHQPELRQPGNHYLVYNDKFIKISDSCPAKPPSAD
>SEQF1516_EDU86116.1 fimbrillin MatB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKKVLAIALVTVFTGMGVAQAADVTAQAVATWSATAKKDTTSKLVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIESDST
ATAFKLTSRLITNTLTQLDTSGSTLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS
>SEQF1516_EDU86117.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDIAISLHFDSQQSFSREFKKLFGCSPRVYRHRDYWDLANIFPSFLIRQQQKTECRLVNFPETPIFGNSFKYDIEVSNK
SPDEEVKLRRHHLARCMKNFKTDTYFVSTFEPSTKSVDLLTVETFAGTVCKQTDSEMPKEWTINRGLYASFRYEGEWEHY
PEWARNLYLMELPARGLARVNGSDIERFYYNEDFVEKDSNDVVCEIFIPVRPV
>SEQF1516_EDU86118.1 propionate catabolism operon regulatory protein PrpR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQLGFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLS
VPVILIKPSGYDVLQALAKAGKLTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAG
LITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDMLGQSPQMEQVRQTILLYARSSA
AVLIEGETGTGKELAAQAIHREYFARHDARQGKKSHPFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHG
GTLFLDEIGEMPLPLQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMRQGQFRRDLFYRLSILRLQLPPLRE
RVADILPLAESFLKVSLAALSAPFSAALRQGLQASETVLVHYDWPGNIRELRNMMERLALFLSVEPTPDLTPQFLQLLLP
ELARESAKIPAPRLLTPQQALEKFNGDKTAAANYLGISRTTFWRRLKS
>SEQF1516_EDU86119.1 phage DNA binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNISVSAPAPAAPLFPVSNHHERFLRLPEVMHLCGLSRSTVYDLISRDAFPKQIPLGGKNVAWAQSEVSAWMADRISAR
GRGCDA
>SEQF1516_EDU86120.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKHLLLLALLLSGISPAQALDVGDISSFMNSDSSTLSKTIKNSTDSGRLINIRLERLSSPLDDGQVISMDKPDELLLTP
ASLLLPAQASEVIRFFYKGPADEKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGTLT
NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKFIPVK
>SEQF1516_EDU86121.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSYSNFSNQIKETINNKFDHEIHDWDIIKNSITTLINKNIHGAGRNIVDFIDLGNWDFISNFSFDDSTRRLELEWHPND
KFHIYIESVVFVEFNDTIYAFLKGYYHNQLSLNRIYNTKCSSCSFENSGSYMVDVYRTVKRVNETIQTPNINCYTTCILT
RPANGHVTSTGFSRNLMDAINISLAEHKIASLHNEVMSIEEYDRDSLQEKGNTARRYLEYILMLVNIRIMHLNNVQYQEQ
MLGSLVSVIEALDYEPLMKNDVEITKDILNACSHHGGVRIEKKDVIFSLEVIENLIKAIKKTDINKLQLDGMFKSIQK
>SEQF1516_EDU86122.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSPVDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRD
WLGLTDPNAAVYTFAGHVFNWVGVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR
>SEQF1516_EDU86123.1 oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFSVLSNNLKMPMMGFGVFQVTDKNVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELFITSKLW
VQDMLNQDTAAAGIEASLKKSGLEYFDLYLLHQAMRDYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMV
NQVELHPYFAQPEALATMKYYNVQPEAWAPLGGGRHKPFENNLLQSIADAHQKSISQVILRWNIQRGVVVIPKSTHQQRI
EENFAIWDFSLTEKEMAQISSLDLGYVGESVKHFNPEFVRGCLAVKIHD
>SEQF1516_EDU86124.1 choline dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFRTQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECG
RGKGLGGSSLINGMCYIRGNAMDLDNWAKEPGLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVTTSKPGVNPLFEA
MIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRTHAMTDHIIFDCKRAVGVEWLEG
DSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAELLAEFDIPLVHDLPGVGENLQDHLEMYLQYECKEPVSLYPALQW
WNQPKIGAEWLFGGTGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSPSRGHVRIK
SRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISPGTECQTDEQLDEFVRNHAETAFHPCGTCKM
GYDEMSVVDGEGRVHGLEGLRVVDASIMPQIITGNLNATTIMIGEKMADMIRGKEALPRSTAGYFVANGMPVRAKKMSRD
LN
>SEQF1516_EDU86125.1 oxidoreductase, FAD/FMN-binding [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNKHPSLFSPFMLTEKIKLRNRIVMAPMTTWSANPDGTISEQELEFYKRRSQNVGLVITGCTYVTPSGIGFTHEFAAYD
DRFINSLEKLAAAAKSGGAPAILQIFHAGNKAIPELVPNNDVISASASSVKSGDFMKRVVQSREMTENEIQETIRAFGDV
TKRAIKAGFDGIELHGAHGFLLQNFFSPLFNQRNDRWGGDLEGRMRFPLAVLQEVKNVVYEYATKPFAIGYRISPEESAT
GGLRIEDTYKLLDRLISSGISYIHTSLVSINDSYPVESPNGPRTIELILNHIAGRVPVIAAGKIRTPSQAQEAISTGLPL
VAIGKGLVINPEWVTLAESGRGHEIQTTLNPQLVPELTIPDKLWDQIQASKGTGWFPLMD
>SEQF1516_EDU86126.1 cysteine-rich domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQPAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSC
TYAVKSYPTYLADEPEWASRAEKVAARMQDLTSFIVNKLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVAHLMEVRPEYLIGADVSCLLNISGRLQREGQKVKVMHIAEVLMSR
>SEQF1516_EDU86127.1 pyridine nucleotide-disulphide oxidoreductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCINIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRN
KNFHNLADMPNIDVINGQAEFINNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGH
LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREERDIADNIATILRDQGVDIILNAHVERISHHENQVQVHSEHAQ
LAVDALLIASGRQPATASLHPENAGIAVNERGAIVVDKRLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGKR
STDDRKNVPYSVFMTPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRILGASLLCVDSH
EMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK
>SEQF1516_EDU86128.1 hypothetical protein ECH7EC4501_1500 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCYCKLTGIILNFYFLHNNFIERQNAYKINKINNKNNLIRNNIKYLKTTKHH
>SEQF1516_EDU86129.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MICCESLLALRAALYRRAVACAWLALSNHQERYSGLTLAELEDAIARELEGFYLRQHGQQRGLEIACALLSDLMESGPLK
ACPVLSLLGMTVMDELCSRHLNKPALH
>SEQF1516_EDU86130.1 LuxR-family transcriptional regulator/cyclic diguanylate phosphodiesterase (EAL) domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASHDLSVFLEEFGATVNLTLPGIVSEKERLLLKLLMEGMSVTEISQYRNRSAKTISHQKKQLYEKLGIQSDITFWRDIF
FQYHPQVISGTGNKNNFYIPDNRCHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGIIPPDQFI
PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNLVKKLGNDKIKLVLELTERNPIP
VTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQAFPVDFIKIDKSFVQMAGVDEISGHIVDNIVELARKPGLSIVAEG
VETQEQADLMIGKGVHFLQGYLYSPPVPGNKFISEWVMKAGG
>SEQF1516_EDU86131.1 sugar ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQMPVLGILALAMAVTMLCGGINLSIIATANACSLVMA
WVATQYPPGIATVVATLLAGAGAAVIIGLCNGVLIAGIRVLPILATLGMMTLLKGINILVTGGSAIANYPSWVLWLNHAQ
WFGIPLPMWLFAAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVISALLCAVAAFLMMSKLNSAKAS
YGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFLLQIIESGFNILGISPYLTMALWGTLLLCFIQARGMLGLDRVV
>SEQF1516_EDU86132.1 hypothetical protein ECH7EC4501_1546 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLQREPLPSLIFHLSSWHDKFPDWKAGSERNAINVSQLTH
>SEQF1516_EDU86133.1 transcriptional repressor BetI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALP
QGSAEQRLQAIVGGNFDETQVSSAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRHQAQEAGYGLAAL
IDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD
>SEQF1516_EDU86134.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTVSIKHTYWDIAADIYFPDDFNSEKKYPAIISAHPIGSCKEQTSGSVYGAALAKAGFIVIAFDASFQGSSGGEPRYLE
DPTMRVKDFSIVVDYLTSLPYVDAGRIGVLGICGGGGYAINAAMTERRIKAIGTVTGANYGRLMREGFTAFNPIGALEAM
AQQRTDEANGAKLRVDDLLPSSPDAALEAGLTEIDLFEATEYYRSPRGYAPNGVNRSLFSHQTVAVGWDAFHLAEVLLTQ
PIMVVVGDRVGAFGAYRDGCEIIGRAASKHKELVVVEGYSHYDLYDKPEPVKQALDKLIPFYKTHL
>SEQF1516_EDU86135.1 IS66 family element, orf1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLDAAAEQPESLAEDPETLSISCEVTFRHGTLRFNGNVSEKLLTLLIQELKR
>SEQF1516_EDU86136.1 transporter, betaine/carnitine/choline transporter (BCCT) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSV
KLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIAL
SVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWT
LFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHPERGFYSLL
AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTVI
MGLPFSFVIFFVMAGLYKSLKVEDYRRESANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQ
ELRLRGAYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYRLETFLLEGSQGNDLMD
YSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA
>SEQF1516_EDU86137.1 sugar ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAELKKRHEFWLALLIVVLFVGLAWRSDEFLTFGNLYDLANNYAMLTILACGLFVVLISGGIDISFPAMTIIAQYGMVLL
LQKIGGNFAVAFALAGCIGILLGLINALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEQGVMLFKYTDA
DGYDYGLGLPLIAMITVVLLTAFIMNFTSVGRKIYALGGNRESASRIGFSVLKLQLFVYGYMGLMSGAAGVVQSWTVMTV
APDSLLGYELTVLAAVVLGGTSLLGGRGTLTGTLLGVVLLAVMQNGLNLLGVSSYWQTLITGIIIVASISATAWSQHQNR
SLL
>SEQF1516_EDU86138.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFFRNRKNIAMTIKEKFSQKYPHASFCTFGDSAALADHLATLIATGVKTASCGSLAGCIEDNAFPMIGEYKIVENSRGEP
VCVIRVIGLHLLRFSDVTAELARKEGEGDLSLEYWRNEHRRFFQAEGSYSPEMDVIFEEYALIDVV
>SEQF1516_EDU86139.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVVLCVAPFFLPPDVSISGVLKNLRLLKPGMSVEHVISIANSSGGLSGLKHAENLPVMDSYSVFMKEVNNRTKTIVMSER
FPEKQKKVLSLLLAGHSWEYSAQFLKTGIRQIWLAEQSLKKRWGIPDSMSLREALLLSSNKFHGDGNALEKTNAMTLREN
GNTNRYSVVVNAGTQVLSLHKYK
>SEQF1516_EDU86140.1 carbonic anhydrase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRLVPELVTQREPGDLFVIRNAGNIVPSYGPEPGGVSAS
VEYAVAALRVSDIVICGHSNCGAMTAIASCQCMDHMPAVSHWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANL
QTHPSVRLALEEGRIALHGWVYDIESGSIAAFDGATRQFVPLAANPRVCAIPLRQPTAA
>SEQF1516_EDU86141.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLEDAIADIARKYNASSWKVTSMRIDNNSTATAVLYK
>SEQF1516_EDU86142.1 putative outer membrane autotransporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFNALLFMQSWFYLDVLLEIVMNKIYRLKWNRSRNCWSVCSELGSRVKGKKSRAVLISAISLYSSLVFADDVIVNQDKT
IDFGKENQSIDYRITVTDNANLVINATDTSRPRLTLASGGGLDITGGKVTINGPLNFLLKGTGFLNVSNAGSELYADDLY
ESNSGMRHDRGYFNVSNGGKIHVKGTSRLTYLQGNVSGEGSQVNSETFFMGVYGSYGGNQYLSVNNGGEVNARKQISLGY
YDQVSDTTLAVSEGGKISAPTISLSTNSELALGAQEGSAAKAAGIIDAEKIEFVWAKTSEKKITLNHTDKDATISADIVS
GSEGLGYINALNGTTYLTGDNSAFSGKVKIEQNGALGITQNIGTAEINNRGKLHLKADDSMTFANKISGNGTISIDSGTV
ELTGNNYAFSGYIDVASGAVAVISEDKNIGRAELDVDGKLQINANKDWVFDNDLEGRGIVEINMGNHEFSFDEFAYTDWF
QGSLAFQNTTFNLEKNAEFLQKGGITAGQGSLVTVGKGAHSISTLGFSGGTVDFGALTAGAQMTEGTVNVSKTLDLRGEG
VIQVSDSDVVRSVSRDIDSALSLTEVDDGNSTIKLVDAQGAEVLGDAGNLQLQDKNGQILSSSAQRDIQQNGQKAAVGTY
DYRLTSGVNNDGLYIGYGLTQLDLHATDSDALVLSSNGKSENAADLSAKITGSGDLAFSSQKGQTVSLSNKDNDYTGVTD
LRSGTLLLNNDNVLGNTHELRLAAETELDMNGHSQTVGTLNGSADSLLSLNGGSLTVTNGGTSTGSLTGSGELNIQGGTL
DIAGDNSNLTANVNIANSANVLVSHAQGLGSANVENNGTLALNNSAEKRAAASVNYALGGNLTNNGTLMTGMSGQQAGNV
LVVKGNYHGNNGQLVMNTVLNGDDSVTDKLVVEGDTSGTTAVTVNNAGGTGAKTLNGIELIHVDGKSEGEFVQAGRIVAG
AYDYTLARGQGANSGNWYLTSGSDSPELQPEPDPMPNPEPNPNPEPNPNPTPTPGPDLNVDNDLRPEAGSYIANLAAANT
MFTTRLHERLGNTYYTDMVTGEQKQTTMWMRHEGGHNKWRDGSGQLKTQSNRYVLQLGGDVAQWSQNGSDRWHVGVMAGY
GNSDSKTISSRTGYRAKASVNGYSTGLYATWYADDESRNGAYLDSWAQYSWFDNTVKGDDLQSESYKSKGFTASLEAGYK
HKLAEFNGSQGTRNEWYVQPQAQVTWMGVKADKHRESNGTLVHSNGDGNVQTRLGVKTWLKSHHKMDDGKSREFQPFVEV
NWLHNSKDFSTSMDGVSVTQDGARNIAEIKTGVEGQLNANLNVWGNVGVQVADRGYNDTSAMVGIKWQF
>SEQF1516_EDU86143.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEHNINLVVKLYSDIPDEQLQSIIKNKIGKYDMEFNYE
>SEQF1516_EDU86144.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKGGGKIIGVKTVGRHDKTRQRRIRQLRTVSDAARAPYPTYGSGL
>SEQF1516_EDU86145.1 sugar ABC transporter, periplasmic sugar-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKRFVINMVSSLLLGAALISAPLQAAEKVVVNISKVDGMPWFNRMGEGVVEAGKAFGVNASQVGPSSTDAPQQVKIIED
LIARKVNAITIVPNDANVLEPVFKKARDAGIVVLTNESPGQPSANWDIEIIDNEKFAAEYVEHMAKRMGGKGGYVIYVGS
LTVPQHNLWADLLVKYQKEHYPDMHEVTRRMPVAESVDVSRRTTLDLMKTYPDLKAVVSFGSNGPIGAGRAVKEKRAKNK
VAVYGMMIPSQAASLIKSGDITEGITYDPASAGYALAAVASTLLKGEEIKPGLEMQNLGKADVDMDKRIIRFHKVLLVNK
DNIDSLY
>SEQF1516_EDU86146.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKIEPSILPSLAWFALIVRAGSFSRAVSEMGITLAALSQNLKSLEERLNTKLIYRTTRNISLTEEGQRLYEVLVSALGQ
IDDALKDVGDTQLEPTGLLRINSSRVAARMLVEPHIGEFLTRYPKTKIELIMDDGLSNIIADGCDVGIRLEQGLDEHMTA
VPVSPLIKLVTVASPDYLKEHGIPETPQELSNHNCLRLRHKSSGALSAWEFSKVVGGNEEFEIEVSGKYISNDDESMIRM
ALNGTGIIQHLDFAIAEHINAGKLQPILEDWAVSFPGFYIYVSSRVRMPSKVRAFIDFMVEKRVKLEN
>SEQF1516_EDU86147.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKYLHLLSRGDKIGLALIRLSIAIVFMWIGLLKFVPYEADSITPFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAW
QSANNTYGFSNGLGVVEVIIALLVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
LKDTLMLAGAVMIMADSAREILKQGSNESSSTLKTEY
>SEQF1516_EDU86148.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDHTKHSILSSLQDKEDDVDELKYSAEDFDSLTVADLYDIEIAMQDFLNDINFENSKDNKVRFDEDTYDFNINGKRRGMF
GKGTRAVMHAIFTICFAEFLSRKGNPFIGFVVLDSPLVTHFDKDRGGSLSDVNSVSLSDSFYHALIKRDYNFQIVILENK
GPTFQIKINDANKIHNLNKNGSSGFYPV
>SEQF1516_EDU86149.1 purine ribonucleoside efflux pump NepI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTLSQTPSPHHQHAYWGGIFAMTLCVFVLIASEFMPVSLLTPIARDLGVTEGLAGRGIAISGALAVLTSLTLSTLAGKM
NRKFLLLGMTVLMAVSGLIIALATSYLMYMVGRAMIGVAIGGFWSMSAATAIRLVPQHQVTRALAIFNAGNALATVVAAP
LGSYLGATVGWRGAFLCLVPMAVVAFIWQCISLPSMDANKSHTSCGAVFRLFSRRMVVVGMIACGLFFMGQFALFTYVRP
FLESVTRVNSLGLSLILLIIGVAGFIGTLVVSIFLNRKCYPTLMAIPGLMAVIAIGLMLTGHHVWMVSLLLGLWGMLATA
APTGWWTWIARTLPDNAEAGGGLMVAVIQLSIALGSTAGGIVFDRLGWQSTFAMSSVLLLCAGVLTFVTARQKAGAL
>SEQF1516_EDU86150.1 amidohydrolase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKENNSRREFLSQSGKMVTAAALFGTSVPLAHAAVSGTTNCEANNTMKITDPHYYLDNVLLETGFDYENGVAVQTRTARQ
TVEIQNGKIVALRENKQHPDATLPHYDAGDKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQP
YTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQAGFECEIVAFPQHGLLLSKSEPLMREAMQAGAH
YVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHLHETTPSGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQV
DELAHRMAAQQISIASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKANLYAQLYIRPNEQNLSRSLF
LATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHKGQLVWGSVAG
>SEQF1516_EDU86151.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNRGEFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTQLNQQQRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKE
LGDQSVVISGDTRLEELGISERLQQECNAVVWDPAKGAKNISQAEQAKVGVVYAEYGLTESGGVVLFSAAERGRSLSLLP
ESSLFILRKSTLLPRVAQLAERLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVHGPVKAVYLIIEDC
>SEQF1516_EDU86152.1 xanthine dehydrogenase family protein, molybdopterin-binding subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEESPNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLPV
ITASNAGALSKGDKNTARLLGGPTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVSQPPEDTPDK
NVGDFDGAFSSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRTDLAKTLKVPVENVRIISPYIGG
GFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIPNNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAV
QQSELLYAGANRHTGLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQIDPADPTRRFSRRQ
LIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGARVHLEPNGTVTVETDMTDIGTGSYTILAQTA
AEMLGVPLEQVAVHLGDSSFPVSAGSGGQWGANTSTSGVYAACVKLREMIASAVGFDPEQSQFADGKITNGTRSAILHEA
TAGGRLTAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARSQVIGAMTMGMGAALME
ELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPISSPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPIT
LDKLLDKLPDVV
>SEQF1516_EDU86153.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU86154.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLYIKLILSIVREISVNTICSLIVVVALSLLSFSSVAKTITAVGSTINSTEKEISLQAEKQGKSYKILGAFFKNRVYMI
AKLTPVSKNDAS
>SEQF1516_EDU86155.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHALTQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHV
DNESTCIVCGTLRLQHSARYFLTSLPETLFLAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
IAQVNTEKNILSLLLHPRLGAVIQQMLEMPGHAWSVESLASIAHMSRASFAQLFRDVSGTTPLAVLTKLRLQIAAQMFSR
EMLPVVVIAESVGYASESSFHKAFVREFGCTPGEYRERVRQLAP
>SEQF1516_EDU86156.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAWTSLNEEASGYYQCLSVYQAGTGVSHPSGQVYRAGVQQRHYRG
>SEQF1516_EDU86157.1 hypothetical protein ECH7EC4501_1530 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKFIGDHLLKFMPDKAFALHSAVQLFSRRQNVVRLMPK
>SEQF1516_EDU86158.1 transcriptional regulator cynR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLGVPLFDRSGRTIHLTDAGEVWRQYASRALQELGAGKR
AIHDVADLTRGSLRIAVTPTFTSYFIGPLMADFYARYPGITLQLQEMSQEKIEDLLCRDELDVGIAFAPVHLPELEAIPL
LTESLALVVAQHHPLAACEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVVIEANSISAVLELIRRTSLSTLL
PAAIATQHDGLKAIPLAPPLLERTAVLLRRKNSWQTAAAKAFLHMALEECADVGENESR
>SEQF1516_EDU86159.1 site-specific recombinase, phage integrase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCIGLCICSCSVWIPIHMPLNDMQIRRAKPEAKAYTFGDGLGLSLLIEPNGSKSWRFRYRYAGKPKMISLGVYPTITLAD
ARSRRDEARKLVAEGKNPSEVRKEQKLAMQTESENAFEKIAREWHQLKSAKWSAGYASDIMEAFKNDIFPYVGTRPVGEI
KPLELLNVLRKIEKRGALEKMRKVRQRCSEVFRYAIATGRAEYNPAADLSSALEVHQSNHFPFLKADEIPDFLRALEGYS
GSKLVQIATKLLMITGVRTIELRAALWQEFDLDNAIWEIPAERMKMRRPHLVPLSSQAVDLLNELKIMTGNYRYVFPGRN
DPNRPMSEASINQAIKRIGYGGKVTGHGFRHTLSTILHEQGFESAWIEIQLAHVDKNSIRGTYNHAQYFSGRKSMMDWYS
NLIFERLKRS
>SEQF1516_EDU86160.1 enterobacterial Ail/Lom family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKLYAAILSAAICLAVSGAPAWASEQQATLSAGYLHARTSAPGSDNLNGINVKYRYEFTDTLGLVTSFSYAGDKNRQLT
RYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
GAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF
>SEQF1516_EDU86161.1 polysaccharide biosynthesis protein WzxC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLREKTISGAKWSAIATVIIIGLGLVQMTVLARIIDNHQFGLLTVSLVIIALADTLSDFGIANSIIQRKEISHLELTTL
YWLNVGLGLVVCVAVFLLSDLIGDVLNNPDLAPLIKTLSLAFVVIPHGQQFRALMQKELEFNKIGMIETSAVLAGFTFTV
VSAHFWPLAMTAILGYLVNSAVRTLLFGYFGRKIYRPGLHFSLASVAPNLRFGAWLTADSIINYLNTNLSTLVLARILGA
GVAGGYNLAYNVAVVPPMKLNPIITRVLFPAFAKIQDDTEKLRVNFYKLLSVVGIINFPALLGLMVVSNNFVPLVFGEKW
NSIIPVLQLLCVVGLLRSVGNPIGSLLMAKARVDISFKFNVFKTFLFIPAIVIGGQMAGAIGVTLGFLLVQIINTILSYF
VMIKPVLGSSYRQYILSLWLPFYLSLPTLVVSYVLGIVLKGQLALGMLLAVQIAAGVLAFVVMIVLSRHPLVVEVKRQFC
RSEKMKMLLRAG
>SEQF1516_EDU86162.1 GDP-mannose 4,6-dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKVALITGVTGQDGSYLAEFLLDKGYEVHGIKRRASSFNTERIDHIYQDPHGSNPNFHLHYGDLTDSSNLTRILKEVQP
DEVYNLAAMSHVAVSFESPEYTADVDAIGTLRLLEAIRFLGLENKTRFYQASTSELYGLVQEIPQKESTPFYPRSPYAVA
KLYAYWITVNYRESYGIYACNGILFNHESPRRGETFVTRKITRGLANIAQGLESCLYLGNMDSLRDWGHAKDYVRMQWLM
LQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKMSFVGKGIEEKGIVDSVEGQDAPGVKPGDVIVAVDPRYFRPAEVDTL
LGDPSKANLKLGWRPEITLAEMISEMVAKDLEAAKKHSLLKSHGFSVSLALE
>SEQF1516_EDU86163.1 methionyl tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGHEVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQE
HQTDFAGFNISYDNYHSTHSEENRQLSELIYTRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCE
VCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANKMQEWFESGLQQWDISRDAPYFG
FEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSVSFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTN
LFVHGYVTVNGAKMSKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGF
INKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALADLANRYVDEQAPWVVAKQEGRDADLQAICSM
GINLFRVLMTYLKPVLPKLTERAEAFLNTELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTG
PLADDPIQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQALIGRHTIMVANLAPR
KMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK
>SEQF1516_EDU86164.1 glycosyl hydrolase family 25 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLRITSRKKLTALLCALGLISIVAIYPRQTVNFFYSTAVQITDYIHFYGYRPVKSFAIHIPASYTIHGIDVSRWQERID
WQRVAKMRDNGIRLQFAFIKATEGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVAAPVQARLFLQTVDFSQGDFPAVL
DVEERGKLSAKELRKRVSQWLKMVEKSTGKKPVIYSGAVFYHTNLAGYFNEYPWWVAHYYQRRPDNDGMAWRFWQHSDRG
QVDGINGSVDFNVFNGTEEELQAFVDGIKETP
>SEQF1516_EDU86165.1 colanic acid biosynthesis glycosyl transferase WcaE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLSIITVAFRNLEGIVKTHASLAHLAQAEDISFEWIVVDGGSNDGTREYLENLNGIYNLRFVSEPDNGIYDAMNKGIAM
AQGKFALFLNSGDIFHQDAAYFVRKLKMQKDNVMITGDALLDFGDGHKIKRSAKPGWYIYHSLPASHQAIFFPVSGLKKW
RYDLEYKVSSDYALAAKMYKAGYAFKKLNGLVSEFSMGGVSTTNNMELCADAKKVQRQILHVPGFWAELSWHLRQRTTSK
TKALYNKS
>SEQF1516_EDU86166.1 colanic acid biosynthesis protein WcaM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPFKKLSRRTFLTASSALAFLHTPFARALPARQSVNINDYNPHDWIASFKQAFSEGQTVVVPAGFVCDNINTGIFIPPGK
TLHILGSLRGNGRGRFVLQDGSQVTGEEGGSMHNITLDVRGSDCTIKGLAMSGFGPVTQIYIGGKNKRVMRNLTIDNLTI
SHANYAILRQGFHNQIIGANITNCKFSDLQGDAIEWNVAINDRDILISDHVIERINCTNGKINWGIGIGLAGSTYDNNYP
EDQAVKNFVVANITGSDCRQLIHVENGKHFVIRNIKARNITQDFSKKAGIDNATVAIYGCDNFVIDNIEMINSAGMLIGY
GVIKGNYLSIPQNFRVNNIQLDNTHLAYKLRGLQISAGNAVSFVALTNIEMKRASLELHNKPQHLFLRNIKVMQESSVGP
ALIMNFDMRKDVRGVFMAKEETLLSLANVHAVNEKGQSSVDIDRINHHIVNVEKINFRLPERRE
>SEQF1516_EDU86167.1 hypothetical protein ECH7EC4501_2460 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILTLSRYARDATFLKIDEDRPGAPFFKGWIDDSFTMSMNFDEFRR
>SEQF1516_EDU86168.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDVVNNHLQQRCGQLLQRVETNYRASSTAKGVTTEVVAVGNNDKRKIVLNRYD
>SEQF1516_EDU86169.1 fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHSIIAVAVLSSVFMSAGIFAAEVDTGTLTIKGNIAESPCTFVAGGDSVSINMPTVPTTVFDGKAKYSTYDGAVGVTSS
MLKITCPKTIDGVKLSLITNEKILGNDKAISSSNDTVGYYLYLGDSSDVLDISAPFNIESYKTADGQYAIPFKAKYLKLT
DSGVASGTVNSSLVMRVAQD
>SEQF1516_EDU86170.1 polysaccharide biosynthesis/export protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKSKMKLMPLLVSVTLISGCTVLPGSNMSTMGKDVIKQQDADFDLDKMVNVYPLTPRLIDQLRPRPNVARPNMTLESEI
ANYQYRVGPGDVLNVTVWDHPELTTPAGQYRSSSDTGNWVQPDGTMFYPYIGKVHVVGKTLAEIRSDITGRLATYIADPQ
VDVNIAAFRSQKAYISGQVNKSGQQAITNVPLTILDAINAAGGLTDTADWRNVVLTHNGREERISLQALMQNGDLNQNRL
LYPGDILYVPRNDDLKVFVMGEVKKQSTLKMDFSGMTLTEALGNAEGIDMTTSNASGIFVIRPLKGEGGRNGKIANIYQL
DMSDATSLVMATEFRLQPYDVVYVTTAPVSRWNRLINQLLPTISGVRYMTDTASDIHNW
>SEQF1516_EDU86171.1 nickel/cobalt efflux protein RcnA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIAIKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKR
FTAQSAEPWLQLISAVIIISTAFWMFWRTWRGERNWLENMHEHHHHDHEHHQDHDHDHDHDHDHEHHHHHEHGDNEEYQD
AHARAHANDIKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGATLVVSFSIGLALTLVTVGVGAAIS
VQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR
>SEQF1516_EDU86172.1 colanic acid biosynthesis protein WcaK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLLILGNHTCGNRGDSAILRGLLDAINILNPHTEVDVMSRYPVSSSWLLNRPVMGDPLFLQMKQHNSAAGVVGRVKKVL
RRRYQHQVLLSRVTDTGKLRNIAIAQGFTDFVRLLSGYDAIIQVGGSFFVDLYGVPQFEHALCTFMAKKPLFMIGHSVGP
FQDEQFNQLANYVFGHCDALILRESVSLDLMKRSNITTAKVEHGVDTAWLVDHHTEDFTASYAVQHWLDVAAQQKTVAIT
LRELAPFDKRLGTTQQVYEKAFAGVVNRILDEGYQVIALSTCTGIDSYNKDDRMVALNLRQHISDPARYHVVMDELNDLE
MGKILGACELTVGTRLHSAIISMNFATPAIAINYEHKSAGVMQQLGLPEMAIDIRHLLDGSLQAMVADTLGQLPALNARL
SEAVSRERQTGMQMVQSVLERIGEVK
>SEQF1516_EDU86173.1 glycosyl transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKETVSIIMPVYNGAKTIISSVESIIHQSYQDFVLYIIDDCSTDDTFSLINSRYKNNQKIRILRNKTNLGVAESRNYGI
EMATGKYISFCDADDLWHEKKLERQIEVLNNECVDVVCSNYYVIDNKRNIVGEVNAPHVINYRKMLMKNYIGNLTGIYNA
NKLGKFYQKKIGHEDYLMWLEIINKTNGAICIQDNLAYYMRSNNSLSGNKIKAAKWTWSIYREHLHLSFPKTLYYFLLYA
SNGVMKKITHSLLRRKETKK
>SEQF1516_EDU86174.1 ADP-ribosylglycohydrolase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTERILGALYGQALGDAMGMPSELWPRSRVKAHFGWIDRFLPGPKENNAACYFNRAEFTDDTSMALCLADALLEREGKI
DPNLIGRNILDWALRFDAFNKNVLGPTSKIALNAIRDGKPVAELENNGVTNGAAMRVSPLGCLLPARDVDSFINDVALAS
SPTHKSDLAVAGAVVIAWAISRAIDGESWSAIVDSLPSIARHAQQKRTTTFSASLAARLEIALKIVRNADGTESASEQLY
QVVGAGTSTIESVPCAIALVELAQTDPNRCAVLCANLGGDTDTIGAMATAICGALHGINAIDPALKAELDAVNQLDFNRY
ATALAKYRQQREAA
>SEQF1516_EDU86175.1 deoxycytidine triphosphate deaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTFRGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDESEA
FYLHPGELALAVTLESVTLPADLVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSF
EPLSGPAARPYNRREDAKYRNQQGAVASRIDKD
>SEQF1516_EDU86176.1 putative prophage tail fibre C-terminus family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNILKKLMQRLCGCGKHDGREHGQSLTAQLRLGPADILESDENGIIPEQDRVITQVVILDADKKQIQCVVRPLQILRADG
TWENIGGMK
>SEQF1516_EDU86177.1 putative colanic acid biosynthesis acetyltransferase wcaF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDLSGFSVPKGFRGGNAIKVQLWWAVQATIFAWSPQVLYRWRAFLLRLFGAKIGKNVVIRPSVKITYPWKLTLGDYVWV
GDDVNLYTLGEITIGAHSVISQKSYLCTGSHDHASQHFTINATPIVIGEKCWLATDVFVAPGVTIGDGTVVGARSSVFKS
LPANVVCRGNPAVVIRKRVETE
>SEQF1516_EDU86178.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSWDLSYIGEKQIAKMYSTESGNVSVSFIDANPIIFVLHLVNDDGRKGTYNISECSEL
>SEQF1516_EDU86179.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALTETANFVFVVIYTAVSHSLPDATLPRLIRPTKPNRRSDKAFTPHPTISA
>SEQF1516_EDU86180.1 fructose-bisphosphate aldolase, class 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNNRPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHS
AGASFAANPLYFDPKNIVELAIEAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMG
AVAVGATIYFGSEESRRQIEEISAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSADLTGQANHLAATIGADIVKQKM
AENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQLANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILG
RKAFKKSMADGVKLINAVQDVYLDSKITIA
>SEQF1516_EDU86181.1 galactitol-1-phosphate 5-dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDA
VACVPLLPCFTCPECLKGFYSQCAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCE
NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVP
QTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKILRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHR
GSFESFAQAVRDIARNAMPGKVLLIP
>SEQF1516_EDU86182.1 sensor histidine kinase BaeS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIKHGNEQRLQLLSDALGEQYAQHGNWRFLRNNDRFVFQ
ILRSFEHDNSEDKPGPGMPPHGWRTQFWVVDQNNKVLVGPRAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFD
KQQRQTSWLIVALATLLAALATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDELGKLAQDFNQLASTLEKNQQM
RRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPETVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLE
VAGGAFRERFASRGLKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFADSAPGVSDD
QLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGGVSITVELPLERDLQREV
>SEQF1516_EDU86183.1 phage minor tail protein L [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDIHGESLIESVKSEQSPRVVLWEIDLTVQGGERYFFCNELNEKGEAVTWQGREYQAYPIDGSGFEMNGKGSSARPSLT
VSNLFGLVTGMAEDLQSLVGATVVRRRVYARFLDAVNFVAGNPEADPEQELSDRWVVEQMSELTAMTASFVLATPTETDG
ALFPGRIMLANTCMWDYRGDECGYNGPAVADEFDNPTTDIRKDRCSKCMRGCEMRGMVANFGGFLSINKLSQ
>SEQF1516_EDU86184.1 GDP-mannose 4,6-dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKVALITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPHTCNPKFHLHYGDLSDTSNLTRILREVQP
DEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAIRFLGLEKKTRFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
KLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKMQWMM
LQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAPGVKPGDVIIAVDPRYFRPAEVETL
LGDPTKAHEKLGWKPEITLREMVSEMVANDLEAAKKHSLLKSHGYDVAIALES
>SEQF1516_EDU86185.1 diacylglycerol kinase catalytic domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKGDAARYVEEARKLGVATVIAGGGDGTINEVSTALIQC
EGDDIPALGILPLGTANDFATSVGIPEALDKALKLAIAGNAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALG
GVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALINDGLLQLRIFTGDEILPALVSTLK
SDEDNPNIIEGASSWFDIQAPHEITFNLDGEPLSGQNFHIEILPAALRCRLPPDCPLLR
>SEQF1516_EDU86186.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSNDILRSVRYILKANNNDLVRILALGNVEATAEQIAVWLRKEDEEGFQRCPDIVLSSFLNGLIYEKRGKDESALALEP
ERRINNNIVLKKLRIAFSLKTDDILAILTEQQFRVSMPEITAMMRAPDHKNFRECGDQFLRYFLRGLAARQHVKKS
>SEQF1516_EDU86187.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLLVTVIFVAMMPNAFALSHGDSATLKEGTFNCKKLTDFYEMISYIQDNDQQAMLSLITSNKCRVLDESMTVEIQSVD
DKGFVSFITPGGHGGWAVKQFFEN
>SEQF1516_EDU86188.1 nucleoside transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTTTKLSFMMFVEWFIWGAWFVPLWLWLSKSGFSAGEIGWSYACTAIAAILSPILVGSITDRFFSAQKVLAVLMFTGAA
LMYFAAQQTTFAGFFPLLLAYSLTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQMLGYADISPT
NIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILLRDKNFLVFFFCSFLFAMPLAFYYIFANGYLTEVG
MKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLLLGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGVSYDFYYVT
AYIYVDKKAPVHMRTAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYQEPVNGLTFNWSGMWTFGAVMIAIIAVLFMIFF
RESDNEITAIKVDDRDIALTQGEVK
>SEQF1516_EDU86189.1 galactitol utilization operon repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTMNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLEQKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQ
LASAPKNRIAQAAVKMIHEGMTVILDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMH
GSIAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNRRGFNQVLPIEKIDIIITDDA
VSDVDKLALQKTRVKLITV
>SEQF1516_EDU86190.1 PTS system, galactitol-specific IIC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSEVMRYILDLGPTVMLPIVIIIFSKILGMKAGDCFKAGLHIGIGFVGIGLVIGLMLDSIGPAAKAMAENFDLNLHVVD
VGWPGSSPMTWASQIALVAIPIAILVNVAMLLTRMTRVVNVDIWNIWHMTFTGALLHLATGSWMIGMAGVVIHAAFVYKL
GDWFARDTRNFFELEGIAIPHGTSAYMGPIAVLVDAIIEKIPGVNRIKFSADDIQRKFGPFGEPVTVGFVMGLIIGILAG
YDVKGVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAKQARSRLQAKFGGQEFLIGLDPALLLGHTAVVSASLIFIPLTILI
AVCVPGNQVLPFGDLATIGFFVAMAVAVHRGNLFRTLISGVIIMSITLWIATQTIGLHTQLAANAGALKAGGMVASMDQG
GSPITWLLIQVFSPQNIPGFIIIGAIYLTGIFMTWRRARGFIKQEKVVLAE
>SEQF1516_EDU86191.1 multidrug resistance protein MdtC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATPLERSLGRIAGVSEM
TSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST
QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAE
YQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIA
QDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVV
DDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLT
LTPMMCGWMLKASKPREQKRLRGFGRMLVALQQGYGKSLKWVLNHTRLVGMVLLGTIALNIWLYISIPKTFFPEQDTGVL
MGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGA
NLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDV
QAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSA
ASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVHPLTI
LSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLA
ALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKSKQTVTE
>SEQF1516_EDU86192.1 putative DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIETFDSVWDAVSDTPEQAENMRIRAELVTIINNWIEQQGFSQAQAASALGVTQPRISELARGKIQIFSIDKLITMMAH
AGLHIQRIEVQYPHAA
>SEQF1516_EDU86193.1 phosphomannomutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLTCFKAYDIRGKLGEELNEDIAWRIGRAYGEFLKPKTIVLGGDARLTSETLKLALAKGLQDAGVDVLDIGMSGTEEI
YFATFHLGVDGGIEVTASHNPMDYNGMKLVREGARPISGDTGLRDVQRLAEANDFPPVDETKRGRYQQINLRDAYVDHLF
GYINVKNLTPLKLVINSGNGAAGPVVDAIEARFKALGAPVELIKVHNTPDGNFPNGIPNPLLPECRDDTRNAVIKHGADM
GIAFDGDFDRCFLFDEKGQFIEGYYIVGLLAEAFLEKNPGAKIIHDPRLSWNTVDVVTAAGGTPVMSKTGHAFIKERMRK
EDAIYGGEMSAHHYFRDFAYCDSGMIPWLLVAELVCLKGKTLGELVRDRMAAFPSSGEINSKLAQPVEAINRVEQHFSRE
ALAVDRTDGISMTFADWRFNLRSSNTEPVVRLNVESRGDVPLMEARTRTLLTLLNE
>SEQF1516_EDU86194.1 colanic acid biosynthesis glycosyl transferase WcaA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKDNPLISIYMPTWNRQQLAIRAIKSVLRQDYSNWEMIIVDDCSTSWEQLQQYVTALNDPRITYIHNDINSGACAVRNQA
IMLAQGEYITGIDDDDEWTPNRLSVFLAHKQQLVTHAFLYANDYVCQGEVYSQPASLPLYPKSPYSRRLFYKRNIIGNQV
FTWAWRFKECLFDTELKAAQDYDIFLRMVVEYGEPWKVEEATQILHINHGEMQITSSPKKFSGYFHFYRKHKDKFDRASK
KYQLFTLYQIRNKRMTWRTLLTLLSVRNGKRLADGIRGR
>SEQF1516_EDU86195.1 DNA-binding response regulator BaeR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLSYVRQTPPDLILLDLMLPGTDGLTLCREIRRFS
DIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAEQSFIRAVYGVGYRWEADACRIV
>SEQF1516_EDU86196.1 tail assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNISAEPEAYFRIAPEDWLQAEMQGEIVALVHSHPGGLPWLSEADRRLQIKSALPWWLVCRGEIHKFRCVPHLTGRRFEH
GVTDCYTLFRDAYHLAGTDMPDFEREDDWWRNGQNLYLDNMEATGFYRISLPSAQPGDILLCCFGASVANHAAIYCGNGE
LLHHLPEQLSKRERYSEKWQRRTHSAWRHRHWHVSAFTGIYNDLAAASACM
>SEQF1516_EDU86197.1 perosamine synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYIPVYQPSLTGKEKEYVNECLDSTWISSKGNYIQKFENKFAEQNHVQYATTVSNGTVALHLALLALGISEGDEVIVPT
LTYIASVNAIKYTGATPIFVDSDNETWQMSVSDIEQKITNKTKAIMCVHLYGHPCDMEQIVELAKSRNLFVIEDCAEAFG
SKYKGKYVGTFGDISTFSFFGNKTITTGEGGMVVTNDKTLYDRCLHFKGQGLAVHRQYWHDVIGYNYRMTNICAAIGLAQ
LEQADDFISRKREIADIYKKNINSLVQVHKESKDVFHTYWMVSILTRTAEEREELRNHLADKLIETRPVFYPVHTMPMYS
EKYQKHPIAEDLGWRGINLPSFPSLSNEQVIYICESINEFYSDK
>SEQF1516_EDU86198.1 bacteriophage lambda tail assembly protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTAAEAIRALSLQVPGFRRQMNEGWYQIRIAGYDTAPEAVYARLHEQLGEGTVIHIVPRLAGAGKGGLQIVLGAAAIVG
SFFTAGASMALWGSALAAGGFSATTMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGRQNTYFSSLDNMIAQGNPMPVP
YGEMLVGSRRISQDISTRDEGGGGTVVVVGRQG
>SEQF1516_EDU86199.1 tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVKISGVLKDGTGKPVENCTIQLKARRNSATVVVNTVASENPDEAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYED
SQPGTLNDFLGAMSEDDVRPEALRRFELMVEEAARHAEEAKKNAGEAETSARNAGISASQAEESAANADTSAGDALESAR
QAAESAAAAKQSEEASSSSASAAAQKASESSQSAAEAELSRKTAESAAGNAARDATTATEKARESAESAQSAEQSRIAAE
EAVNRIPTVVGPPGPKGEQGPAGPQGPKGDKGERGDTGPVGATGERGPAGDAGPAGPQGPKGDRGERGETGLTGNAGPQG
PKGDTGAAGPAGPQGPKGETGAAGPVGATGPQGPKGDPGETQIRFRLGPASIIETNSNGWFPDTDGALITGLTFLDPKDA
TQVQGLFRHLQVRFGDGPWQDVKGLDEVGSDTGRTGE
>SEQF1516_EDU86200.1 PTS system, galactitol-specific IIB component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNLFVRSGISFVDRSEVLTHIGNEMLAKGVVHDTWPQALIAREAEFPTGIMLEQHAIAIPHCEAIHAKSSAIYLLRPTN
KVHFQQADDDNDVAVSLVIALIVENPQQQLKLLRCLFGKLQQPDIVETLITLPETQLKEYFTKYVLDSDE
>SEQF1516_EDU86201.1 membrane protein, TerC family/CBS/transporter associated domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEWIADPSIWAGLITLIVIELVLGIDNLVFIAILAEKLPPKQRDRARVTGLLLAMLMRLLLLASISWLVTLTQPLFSFRS
FTFSARDLIMLFGGFFLLFKATMELNERLEGKDSNNPTQRKGAKFWGVVTQIVVLDAIFSLDSVITAVGMVDHLLVMMAA
VVIAISLMLMASKPLTQFVNSHPTIVILCLSFLLMIGFSLVAEGFGFVIPKGYLYAAIGFSVMIEALNQLAIFNRRRFLS
ANQTLRQRTTEAVMRLLSGQKEDAELDAETASMLVDHGNQQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAP
EDEIRQLLERNQHTRLVVTDGDDAEDLLGVVHVIDLLQQSLRGEPLNLRVLIRQPLVFPETLPLLPALEQFRNARTHFAF
VVDEFGSVEGIVTLSDVTETIAGNLPNEVEEIDARHDIQKNADGSWTANGHMPLEDLVQYVPLPLDEKREYHTIAGLLME
YLQRIPKPGEEVQVGDYLLKTLQVESHRVQKVQIIPLRKDGEMEYEV
>SEQF1516_EDU86202.1 putative colanic acid biosynthesis acetyltransferase wcaB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLEDLRANSWSLRPCCMVLAYRVAHFCSVWRKKNVLNNLWAAPLLVLYRIITECFFGYEIQAAATIGRRFTIHHGYAVVI
NKNVVAGDDFTIRHGVTIGNRGADNMACPHIGNGVELGANVIILGDITLGNNVTVGAGSVVLDSVPDNALVVGEKARVKV
IK
>SEQF1516_EDU86203.1 class II aldolase, tagatose bisphosphate family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAPVIIAGTPGTFTHAGTENLLALVSAMAKHYHHPLAIH
LDHHTKFDDIAQKVRSGVRSVMIDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQA
REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDIQQTIKLGICKINVATELKNAFS
QALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIADCGCEGRA
>SEQF1516_EDU86204.1 colanic acid biosynthesis glycosyl transferase WcaC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNILQFNVRLAEGGAAGVALDLHQRALQQGLASHFVYGYGKGGKESVSHQNYPQVIKHTPRMTAMANIALFRLFNRDLFG
NFNELYRTITRTPGPVVLHFHVLHSYWLNLKSVVRFCEKVKNHKPDVTLVWTLHDHWSVTGRCAFTDGCEGWKTGCQKCP
TLNNYPPVKIDRAHQLVAGKRQLFREMLALGCQFISPSQHVADAFNSLYGPGRCRIINNGIDMATEAILADLPPVRETQG
KPKIAVVAHDLRYDGKTNQQLVREMMALGDKIELHTFGKFSPFTAGNVVNHGFETDKRKLMSALNQMDALVFSSRVDNYP
LILCEALSIGVPVIATHSDAAREVLQKSGGKTVSEEEVLQLVQLSKPEIAQALFGTTLAEFSQRSRAAYSGQQMLEEYVN
FYQNL
>SEQF1516_EDU86205.1 DNA-damage-inducible protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVEICIAKEKITKMPNGAVDALKEELTRRISKRYDDVEVIVKATSNDGLSVTRTADKDSAKTFVQETLKDTWESADEWF
VR
>SEQF1516_EDU86206.1 phosphomethylpyrimidine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQNTRGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGM
LAETDIVEAVAERLQRYQIQNVVLDTVMLAKSGDPLLSPSAVATLRSRLLPQVSLITPNLPEAAALLDAPHARTEQEMLE
QGRALLAMGCGAVLMKGGHLDDEQSPDWLFTREGEQRFTAPRIMTKNTHGTGCTLSAALAALRPRHTNWADTVQEAKSWL
SSALAQADTLEVGHGIGPVHHFHAWW
>SEQF1516_EDU86207.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPTLYTATGECVTPGRELGKGGEGAVYDINEFVDSVAKIYHTPPPALKQDKLAFMAATADAQLLNYVAWPQATLHGGRG
GKVIGFMMPKVSGKEPIHMIYSPAHRRQSYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVLIDS
DSFQINANGTLHLCEVGVSHFTPPELQTLPSFVGFERTANHDNFGLALLIFHVLFGGRHPYSGVPLISDAGNALETDIAH
FRYAYASDNQRRGLKPPPRSIPLSMLPGDVEAMFQQAFTESGVATARPTAKAWVAALDLLRQQLKKCTVSAMHVYPGHLT
DCPWCALDNQGVIYFIDLGEEVITTSGDFVLAKVWAMVMASVAPPALQLPLPDHFQPTGRPLPLGLLRREYIILIEIALS
ALSLLLCGLQAEPRYIILVPVLAAIWIIGSLTSKVYKAEIQQRREAFNRAKMDYDHLVSQIQQLGGLEGFIAKRAMLEKM
KDEILGLPEEEKRALAALHDTARERQKQKFLEGFFIDAASIPGVGPARKAALRSFGIETAADVTRRGVKQVKGFGDHLTQ
AVIDWKASCERRFVFRPNEAVTPAERQAVMAKMAAKRHRLESALTVGATELQRFRLHAPARTMPLMEPLRQAAEKLAQAQ
ADLSRC
>SEQF1516_EDU86208.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKYADHLKNVTAKEFCEGVGLKASFATEFSKMRNLTERLKAAGLDTTKL
>SEQF1516_EDU86209.1 hydroxyethylthiazole kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQVDLLSSAQSAHTLHLFHQHSPLVHCMTNDVVQTFTANTLLALGASPAMVIETEEASQFAAIASALLINVGTLTQPRAQ
AMRAAVEQAKSSQTPWTLDPVAVGALDYRRHFCHELLSFKPAAIRGNASEIMALAGVANGGRGVDTTDAAVNAIPAAQTL
ARETGAIVVVTGEVDYVTDGHRAVGIHGGDPLMTKVVGTGCALSAVVAACCALPGDMLENVASACHWMKQAGERAVARSE
GPGSFVPHFLDALWQLTQEVQA
>SEQF1516_EDU86210.1 von Willebrand factor type A domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEQITFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAGLVTFRDELLADPLALKRVELGIVTFGPVHVEQPFTSA
ANFFPPILFAQGDTPMGAAITKALDMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFQGEEDKKFAFFSIG
VQGADIKTLAQISVRQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTSV
>SEQF1516_EDU86211.1 gdp-mannose mannosyl hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLHSQDFATIVRSTPLISIDLIVENEFGEILLGKRINRPAQGYWFVPGGRVLKDEKLQTAFERLTEIELGIRLPLSVGK
FYGIWQHFYEDNSMGGDFSTHYIVIAFLLKLQPNILKLPKSQHNAYCWLSRAKLINDDDVHYNCRAYFNNKTNDAIGLDN
KDIICLMRQ
>SEQF1516_EDU86212.1 hypothetical protein ECH7EC4501_2450 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIYGGLLAKKYLESRSQKIKKPAGEAGSFIYYSDANLLIVQHFVPTNKL
>SEQF1516_EDU86213.1 colanic acid biosynthesis glycosyl transferase WcaL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVGFFLLKFPLSSETFVLNQITAFIDMGFEVEIVALQKGDTQNTHVAWTKYNLAARTRWLQDEPTGKVAKLRHRASQTL
RGIHRKNTWQALNLKRYGAESWNLILSAICGQVATPFRADVFIAHFGPAGVTAAKLRELGVIHGKIATIFHGIDISSREV
LNHYTPEYQQLFRRGDLMLPISDLWAGRLQKMGCPREKIAVSRMGVDMTRFSPRPVKAPATPLEIISVARLTEKKGLHVA
IEACRQLKEQGVAFRYRILGIGPWERRLRTLIEQYQLEDVVEMPGFKPSHEVKAMLDDADVFLLPSVTGADGDMEGIPVA
LMEAMAVGIPVVSTLHSGIPELVEADKSGWLVPENDARALAQRLAAFSQLDTDELAPVVKRAREKVEHDFNQQVINRELA
SLLQAL
>SEQF1516_EDU86214.1 von Willebrand factor type A domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSELNDLLTTRELQRWRLILGEAAETTLCGLDDNARQIDHALEWLYGRDPERLQRGERSGGLGGSNLTTPEWINSIHTLF
PQQVIERLESDAVLRYGIEDVVTNLDVLERMQPSESLLRAVLHTKHLMNPEVLAAARRIVRQVVEEIMARLAKEVRQAFS
GVRDRRRRSSIPLARDFDFKSTLRANLQHWHPQHGKLYIESPRFNSRIKRHSEQWQLVLLVDLSGSMVDSVIHSAVMAAC
LWQLPGIRTHLVAFDTSVVDLTADVADPVELLMKVQLGGGTNIASAVEYGRQLIEQPAKSVIILVSDFYEGGSSSLLTHQ
VKKCVQSGIKVLGLAALDSTATPCYDRDMAQALVNVGAQIAAMTPGELATWLAENLQS
>SEQF1516_EDU86215.1 multidrug resistance protein mdtD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFT
AIVLFTLGSLFCALSGTLNELLLARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEY
ASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSKGTGLSPLAITGLVAVGVVALVL
YLLHARNNNRALFSLKLFRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQV
VNRFGYRRVLVATTLGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNSLLSMIMQL
SMSIGVTIAGLLLGLFGSQHVSVDSSTTQTVFMYTWLSMAFIIALPAFIFARVPNDTHQNVAISRRKRSAQ
>SEQF1516_EDU86216.1 GDP-L-fucose synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRQRIFIAGHRGMVGSAIRRQLEQRGDVELVLRTRDELNLLDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFI
YQNMMIESNIIHAAHQNDVNKLLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRS
VMPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAASIHVMELAHEVWLENTQPML
SHINVGTGVDCTIRELAQTIAKVVGYKGRVVFDASKPDGTPRKLLDVTRLHQLGWYHEISLEAGLASTYQWFLENQDRFR
G
>SEQF1516_EDU86217.1 hypothetical protein ECH7EC4501_2449 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVQKELVAIYDYEVPVPEDPFSFRLEIHKCSELFTGSVYRLERFRLRSTFHQRDREDADPLINDALIYIRDECIDERKL
RGESPETVIAIFNRELQNIFNQEIE
>SEQF1516_EDU86218.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFIGFDYGTANCSVAVMRDGKPHLLKMENDSTLLPSMLCAPTREAVSEWLYRHHDVPADDDETQALLRRAIRYNREEDID
VTAKSVQFGLSSLAQYIDDPEEVWFVKSPKSFLGASGLKPQQVALFEDLVCAMMLHIRQQAQAQLPEAITQAVIGRPINF
QGLGGDEANAQAQGILERAAKRAGFRDVVFQYEPVAAGLDYEATLQEEKRVLVVDIGGGTTDCSLLLMGPQWRSRLDREA
SLLGHSGCRIGGNDLDIALAFKNLMPLLGMGGETEKGIALPILPWWNAVAINDVPAQSDFYSSANGRLLNDLVRDAREPE
KVALLQKVWRQRLSYRLVRSAEECKIALSSVAETRASLPFISDELATLISQQGLESALSQPLARIQEQVQLALDNAQEKP
DVIYLTGGSARSPLIKKALAEQLPGIPIAGGDDFGSVTAGLARWAEVVFR
>SEQF1516_EDU86219.1 gram-negative pilus assembly chaperone [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKGLLSLLISSMIFPVHAGMVIFGTRIIYPAEQKEVMVQLMNQGNRSSLMQAWIDDGDTSLPPEKIQVPFMLTPPVVKVA
ANSGQQIKIKIMPNKLPSNKESIFYLNVLDIPPNSPEDEGKNALKFAMQNRIKLFYRPAGIAPVNKTTFKKLRVSRSGNN
VVIKNDSPNWVTISDVKANNVKVNYETIMIAPQESQNVSEKNNNANGWQLTIIDDHGNYISDKI
>SEQF1516_EDU86220.1 UDP-N-acetylglucosamine 4-epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDNVLLIGASGFVGTRLLETAIADFNIKNLDKQQSHFYPEITQIGDVRDQQALDQALAGFDTVVLLAAEHRDDVSPTSL
YYDVNVQGTRNVLAAMEKNGVKNIIFTSSVAVYGLNKHNPDENHPHDPFNHYGKSKWQAEEVLREWYNKAPTERSLTIIR
PTVIFGERNRGNVYNLLKQIAGGKFMMVGAGTNYKSMAYVGNIVEFIKYKLKNVAAGYEVYNYVDKPDLNMNQLVAEVEQ
SLNKKIPSMHLPYPLGMLGGYCFDILSKITGKKYAVSSVRVKKFCATTQFDATKVHSSGFVAPYTLSQGLDRTLQYEFVH
AKKDDITFVSE
>SEQF1516_EDU86221.1 glycosyl transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKISVITVTYNNAEGLEKTLSSLSILKIKPFEIIIVDGGSTDGTNRVISRFTSMNITHVYEKDEGIYDAMNKGRMLAKGD
LIHYLNAGDSVIGDIYKNIKEPCLIKVGLFENDKLLGFSSITHSNTGYCHQGVIFPKNHSEYDLRYKICADYKLIQEVFP
EGLRSLSLITSGYVKYDMGGVSSKKRILRDKELAKIMFEKNKKNLIKFIPISIIKILFPERLRRVLRKMQYICLTLFFMK
NSSPYDNE
>SEQF1516_EDU86222.1 colanic acid polymerase WcaD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTSIRICSYLLLPLIYLLVNVKITQLGESFPITIVTFLPVLLLLFLERISVKKLMIALGICAGLTAFNYLFGQSLDASK
YVTSTMLFVYIVIIIGMVWSIRFKTISPHNHRKILRFFYLVVGLVVALAAVEMAQIILTGGSSIMESISKYLIYSNSYVL
NFIKFGGKRTTALYFEPAFFALALISIWLSIKQFGIKTPKTDAMILAGIILSGSFSGVMTFILFYLLEWAFQYLNKEAIK
KKLPLALISLAVFLVGVVIAFPYISTRLGDLGTEGSSSYYRIVGPLVMVGYSLTHIDGVVRFGSLYEYVASFGIFNGADV
GKTIDNGLYLLIIYFSWFAVFLSLWYMGKVIKMMINAFGDNRNFRVQLYLFTPVSLFFTGSIFSPEYAFLIVCPFILRKA
LNITR
>SEQF1516_EDU86223.1 capsular polysaccharide biosynthesis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNLKKRERAKTNASLISMVQRFSDITIMFAGLWLVCEVSGLSFLYMHLLVALITLVVFQMLGGITDFYRSWRGVRAATE
FALLLQNWTLSVIFSAGLVAFNNDFDTQLKIWLAWYGLTSIGLVVCRSCIRIGAGWLRNHGYNKRMVAVAGDLAAGQMLM
ESFRNQPWLGFEVVGVYHDPKLGGVSNDWAGNLQQLVEDAKAGKIHNVYIAMQMCDGARVKKLVHQLADTTCSVLLIPDV
FTFNILHSRLEEMNGVPVVPLYDTPLSGVNRLLKRAEDIVLATLILLLISPVLCCIALAVKLSSPGPVIFRQTRYGMDGK
PIKVWKFRSMKVMENDKVVTQATQNDPRVTKVGNFLRRTSLDELPQFINVLTGGMSIVGPRPHAVAHNEQYRQLIEGYML
RHKVKPGITGWAQINGWRGETDTLEKMEKRVEFDLEYIREWSVWFDIKIVFLTVFKGFVNKAAY
>SEQF1516_EDU86224.1 PTS system, galactitol-specific IIB component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRKIIVACGGAVATSTMAAEEIKELCQSHNIPVELIQCRVNEIETYMDGVHLICTTARVDRSFGDIPLVHGMPFVSGVG
IEALQNKILTILQG
>SEQF1516_EDU86225.1 transcriptional regulator, GntR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHGNILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRS
RGYGTQINNIFEYSLKEARGFSQQVVLRGKKPDTLWVNKRVVKCPEEVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESW
VPAHLIHDVDAIGISLYDYFRSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVIKQVALDQQQRPIEYSISHCRSD
LYVFVCEE
>SEQF1516_EDU86226.1 sensor histidine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWFAGMYDFNLVLLLLQQMCVFLVIAWLMSKTPLFIPLMQVTVRLPHKFLCYIVFSIFCIMGTWFGLHIDDSIANTRAIG
AVMGGLLGGPVVGGLVGLTGGLHRYSMGGMTALSCMISTIVEGLLGGLVHSILIRRGRTDKVFNPITAGAVTFVAEMVQM
LIILAIARPYEDAVRLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSATALKVAASTEGILRQGFNEVNSMKV
AQVLYLELDIGAVAITDREKLLAFTGIGDDHHLPGKPISSTYTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPL
RGENQRVMGTIKLYEAKNRLFSSINRTLGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIKAVI
RRDSEQASQLVQYLSTFFRKNLKRPSEFVTLADEIEHVNAYLQIEKARFQSRLQVNIAIPQELSQQQLPAFTLQPIVENA
IKHGTSQLLDTGRVAISVRREGQHLMLEIEDNAGLYQPVTNASGLGMNLVDKRLRERFGDDYGISVACEPDSYTRITLRL
PWRDEA
>SEQF1516_EDU86227.1 GDP-mannose mannosyl hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLRQEDFATVVRSTPLVSLDFIVENSRGEFLLGKRTNRPAQGYWFVPGGRVQKDETLEAAFERLTMAELGLRLPITAGQ
FYGVWQHFYDDNFSGTDFTTHYVVLGFRFRVAEEELLLPDEQHDDYRWLTPDALLASNDVHANSRAYFLAEKRAGVPGL
>SEQF1516_EDU86228.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKKLAFLDTSLDDLRAFPESSRQEIGYQLDRIQQGLNPYDWKPFSTIGPGVREIRTRDADGIYRVMYVAKFEEAVYVLH
CFQKKTQTTSQSDIDLAKRRYKELVQERKNEN
>SEQF1516_EDU86229.1 low molecular weight protein-tyrosine-phosphatase wzb [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFNNILVVCVGNICRSPTAERLLQRYHPELKVESAGLGALVGKGADPTAISVAAEHQLSLEGHCARQISRRLCRNYDLIL
TMEKRHIERLCEMAPEMRGKVMLFGHWDNECEIPDPYRKSRETFAAVYTLLERSARQWAQALNAEQV
>SEQF1516_EDU86230.1 O antigen flippase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKIKKILKFCTLKKYDTSSALGREQERYRIISLSVISSLISKILSLLSLILTVSLTLPYLGQERFGVWMTITSLGAALT
FLDLGIGNALTNRIAHSFACGKNLKMSRQISGGLTLLAGLSFVITAICYITSGMIDWQLVIKGINENVYAELQHSIKVFV
IIFGLGIYSNGVQKVYMGIQKAYISNIVNAIFILLSIITLVISSKLHAGLPVLIVSTLGIQYISGIYLTINLIIKRLIKF
TKVNIHAKREAPYLILNGFFFFILQLGTLATWSGDNFIISITLGVTYVAVFSITQRLFQISTVPLTIYNIPLWAAYADAH
ARNDTQFIKKTLRTSLKIVGISSFLLAFILVVFGSEVVNIWTEGKIQVPRTFIIAYALWSVIDAFSNTFASFLNGLNIVK
QQMLAVVTLILIAIPAKYIIVSHFGLTVMLYCFIFIYIVNYFIWYKCSFKKHIDRQLNIRG
>SEQF1516_EDU86231.1 multidrug resistance protein MdtA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPGATKQAQQSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLG
TITAANTVTVRSRVDGQLMALHFQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLTNARRDLARYQQLAKTNLV
SRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQISSGDTTGIVVITQTHPIDLLFTL
PESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTLLSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQN
AVVIPTAALQMGNEGHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVEAQSATTPE
EKATSREYAKKGARS
>SEQF1516_EDU86232.1 phage minor tail protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTFRWKVKPDMEVNSQPSVREVRFGDGYSQRMAAGLNADLKTYRVTLSVTREEARHLEAFLAEHGGWKAFLWKPPYAYR
QIKVTCAGWSARVGMLRVEFSAEFKQVVN
>SEQF1516_EDU86233.1 putative fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMFRNRILLIFILWANFTWAGCRTTASLNITDGINVGEILANETSFSKSVVFTGISCDTSTDKIVYKNIQSDWVEVGPFG
NGEKLKVKIESLGKTSDTIGKSSNAQAVLPYVVKIARGTPDFTGERKSTWFISDTVIANIGGESSSSIDFWLGICKALKF
NWCVNYLTSKLAGDTFTLGLNISYYPKNTTCKPENTVIKVDDIALFQLRNQGKIAANSKEGTITLKCDNLFGDKKQASRN
MVVYLSSSDLVKGSNTILRGKTDNGVGFVLDLTEPPKGTEAAIKISANGDQGAATSLWKTDKPGVSLNSNIINIPVMASY
YVYDEKKVKSGALEATALINVKYD
>SEQF1516_EDU86234.1 regulatory protein GalF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEIVAAGIKEILLVTHASKNAVENHFDTSYELESLLEQR
VKRQLLAEVQSICPPGVTIMNVRQGEPLGLGHSILCARPAIGDNPFVVVLPDVVIDDASADPLRYNLAAMIARFNETGRS
QVLAKRMPGDLSEYSVIQTKEPLDREGKVSRIVEFIEKPDQPQTLDSDIMAVGRYVLSADIWPELERTQPGAWGRIQLTD
AIAELAKKQSVDAMLMTGDSYDCGKKMGYMQAFVKYGLRNLKEGAKFRKGIEKLLSE
>SEQF1516_EDU86235.1 uridine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVIPEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEH
LQALKRGSAIDLPVYSYVEHTRMKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE
>SEQF1516_EDU86236.1 AsmA protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRFLTTLMILLVVLVAGLSALVLLVNPNDFRDYMVKQVAARSGYQLQLDGPLRWHVWPQLSILSGRMSLTAQGASQPLV
RADNMRLDVALLPLLSHQLSVKQVMLKGAVIQLTPQTEAVRSEDAPVAPRDNTLPDLSDDRGWSFDISSLKVADSVLVFQ
HEDDEQVTIRNIRLQMEQDPQHRGSFEFSGRVNRDQRDLTISLNGTVDASDYPHDLTAAIEQINWQLQGADLPKQGIQGQ
GSFQAQWQESRKRLSFNQISLTANDSTLSGQAQVTLTEKPEWQLRLQFPQLNLDNLIPLNETANGENGAAQQGQSQSTLP
RPVISSRIDEPAYQGLQGFTADILLQASNVRWRGMNFTDVATQMTNKSGLLEITQLQGKLNGGQVSLPGTLDATSINPRI
NFQPRLENVEIGTILKAFNYPISLTGKMSLAGDFSGADIDADAFRHNWQGQAHVEMADTRMEGMNFQQMIQQAVERNGGD
VKAAENFDNVTRLDRFTTDLTLKDGVVTLNDMQGQSPVLALTGEGMLNLADQTCDTQFDIRVVGGWNGESKLIDFLKETP
VPLRVYGNWQQLNYSLQVDQLLRKHLQDEAKRRLNDWAERNKDSRNGKDVKKLLEKM
>SEQF1516_EDU86237.1 molybdate metabolism regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTWLRLVITDDTALSTVEKYDFPPLYRDFRNFRAYLAMLLANNGVRGVSRILLEFTEDHSDNPTYLFERISETENLVKWL
WKTNHPDAIQILILGVIGKKKHLEYLSKASQKHPAAAIAAYATLLAIHEDKEWRKALVKLITATPELVCDVIPWVNAKAA
GILSECRPQSVAEECEYATVDMLPELLVSPPWMTKEKKKNTPVFDLPVLPVPSVSDVTPEITKKLTRTYLVTHFQQIAQQ
QATKQTLFTDLPPIKKASWEKHLIPLTPEQQILWHLGFEKWRESGEKIYEKIPAPQSAVDALLRFDFPALNAEFVHYHNN
AYKSWNLIALCYLPGQQAISFLNQIVKEDNYSGEGNILAIFGSAAIPAFMACLQRDPRRLCFFPFFLGVSELALPMAQQL
QKKMSYEDARNWLTDYPRHAAAGLLPVALGKKGKDRDCARQALRLLVNLNQRETIEEIAQGYNQPDVLAALATLFDSDPL
EEYPAKIAPLPGFYQFTLWRRPRLKSNNLPLSDDAMRHLGTMLSFPRDITAYAGLDIIREIFTRESLAEFGWDLYPAWTE
AGAPAKENWAFTSLGILGNDDTARKLTPLIRAWPGESQHKRAVSGLDVLADIGSDVALMLLNGIARKIKFKALQEHAREK
INIVAENRGLTMAELEDRLAPDLGLDSSGSLILDFGPRKFTVGFDETLKPVVCDANGKVLKDLPKPNQSDEKTQATDAVN
LFKQLKKDVRAIASQQIDRLEQAMCQRRRWTAEQFRLFLVEHPLVRHLTRRLLWGVYNDENALITCFRVAEDSTYSDAQD
ELFTLPAGNIGIPHVLEISPESAAAFRQIYADYELLPPFQQLERGSYHLADNERNTHELTRWQGRLCQAGRIVGLERRGW
QRLEESGSVYAMRKTTPHGDLELETEPFSLIYGETGYGDQHPVESVKITSPDDRYGKQSSLTFSMLDDITASELINDIES
LFD
>SEQF1516_EDU86238.1 putative tagatose-6-phosphate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIEATSNQVNQFGGYTGMTPADFREFVFAIADKVGFARE
RIILGGDHLGPNCWQQENVDAAMEKSVELVKAYVRAGFSKIHLDASMSCAGDPIPLAPETVAERAAVLCFAAESVATDCQ
REQLSYVIGTEVPVPGGEASAIQSVHITHVEDAANTLRTHQKAFIARGLTEALTRVIAIVVQPGVEFDHSNIIHYQPQEA
QALAQWIENTRMVYEAHSTDYQTRTAYWELVRDHFAILKVGPALTFALREAIFALAQIEQELIAPENRSGCLAVIEEVML
DEPQYWKKYYRTGFNDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLQGVDIPLGMISQYLPKQFERIQSGELSAIPH
QLIMDKIYDVLRAYRYGCAE
>SEQF1516_EDU86239.1 kinase, PfkB family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGARLHTLLPELTTRQPVMVIGAAVIDVIADAYALPWRGCDIELKQQSVNVGGCALNIAVALKRLGIEAGNALPLGQGV
WAEIIRNRMAKEGLISLIDNAEGDNGWCLALVEPDGERTFMSFSGVENQWNCQWLARLTVAPGSLLYFSGYQLASPCGEL
LVEWLEKLQDVTPFIDFGPRIGDIPEALLARIMACRPLVSLNRQEAEIAAERFALSAEITTLGKQWQEKFATPLIIRLDK
EGAWYFSNDASGCIPAFPTQVVDTIGAGDSHAGGVLAGLASGLPLADAVLLGNAVASWVVGHRGGDCAPTREELLLAHKN
V
>SEQF1516_EDU86240.1 molybdate metabolism regulator MolR homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKELPWLADNAQLELKYKKGKTPLSHRRWPGEPVSVITGSLIQTLGDELLQQAGQKENITWNYDKCSLEWQSAIQQAIN
LTGEHKPSIPALTMAALICIAQNDSQQLLDEIVQQEGLEYATDVVISRQCIARRYESDSLVVTLQYQDEDYGYGYGSATY
NDFDLRLRKHLSLAEESCWQRCADKLIAALPGIPKIRRPFIALILPEKPEIANELASLESSRSSLHSKEWLKVVATDNTA
VKKLERYWGLDVFSDREASYMSQENRFGYAACASLLREQGLAAVPRLAMYAHKEDCGSLLVQINHPQVIRTLLLVADKNK
PSLQRVAKYSKNFPHATLAALAELLALKEPPARPGYPIIEDKKLPAQQKAREEYWRTLLQTLMASQPQLAAEVMSWLSTQ
ARAVLKSYLSALPKPVIDGTDNSNLPEILVSPPWRSKKKMTAPRLDLARLELTPQVYWQPGERERLAATESARYFSTESL
AQRMEQKSGRVVLQELGFGDDVWLFLNYILPGKLDAARNSLIVQWHYYQGRVEEILNGWNSPEAQLAEQALRSGHIEALI
NIWENDNYSRYRPEKSVWNLYLLAQLPREMALTFWLRINEKKHLFAGEDYFLSILGLDALPGLLLAFSHRPKETFPLILN
FGATELALPVARVWRRFAAQRDLARQWILQWPEHTATALIPLVFTKSSDKSEAALLALRLLYEHGHGELLQTVANRWQRT
DVWPALEHLLKQGPMEIYPARIPKAPDFWHPQMWSRPRLITNNQPVTDDALEIIGEMLRFTQGGRFYSGLEQLKTFCQPQ
TLAAFAWDLFTAWQQAGAPAKDNWAFLALSLFGDESTARDLTTQILAWPQGKSARAVSGLNILTLMNNDMALIQLHHISQ
RAKSRPLRDNAAEFLQVVAENRGLSQEELADRLVPTLGLDDPQALSFDFGPRQFTVRFDENLNPVIFDQQNVRQKSVPRL
RADDDQLKAPEALARLKGLKKDATQVSKNLLPRLEAALRTTRRWSLADFHSLFVNHPFTRLVTQRLIWGVYPANEPRRLL
NAFRVAAEGGFCNAQDEPIDLPADALIGIAHPLEMTAEMRSEFAQLFADYEIMPPFRQLARRTVLLTPDESTSNSLTRWE
GKSATVGQLMGMRYKGWESGYEDAFVYDLGEYRLVLKFSPGFNHYNVDSKALMSFRSLRVYRDNKSVTFAELDVFNLSEA
LSAPDVIFH
>SEQF1516_EDU86241.1 colanic acid biosynthesis glycosyl transferase WcaI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKILVYGINYSPELTGIGKYTGEMVEWLAAQGHEVRVITAPPYYPQWQVGENYSAWRYKREEGAATVWRCPLYVPKQPST
LKRLLHLGSFAVSSFFPLMAQRRWKPDRIIGVVPTLFCTPGMRLLAKLSGARTVLHIQDYEVDAMLGLGLAGKGKGGKVA
QLATAFERSGLHNVDNVSTISRSMMNKAIEKGVAAENVIFFPNWSEIARFQHVADADVDALRNQLGLPDNKKIILYSGNI
GEKQGLENVIEAADRLRDEPLIFAIVGQGGGKARLEKMAQQRGLRNMQFFPLQSYDALPALLKMGDCHLVVQKRGAADAV
LPSKLTNILAVGGNAVITAEAHTELGQLCETFPGIAVCVEPESVEALVAGIRQALLLPKHNTVAREYAERTLDKENVLRQ
FINDIRG
>SEQF1516_EDU86242.1 ATPase, AAA family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSPQNNHLQRPPAAVLYADELAKLKQNDNAPCPPGWQLSLPAARAFILGDSAQNISRKVVISPSAVERMLVTLATGRGLM
LVGEPGTAKSLLSELLATSISGDAGLTIQGGASTTEDQIKYGWNYALLINHGPSTEALVPAPLYQGMRDGKIVRFEEITR
TPLEVQDCLLGMLSDRVMTVPELTGEASQLYAREGFNIIATANTRDRGVNEMSAALKRRFDFETVFPIMDFAQELELVAS
ASARLLAHSGIPHKVPDAVLELLVRTFRDLRANGEKKTSMDTLTAIMSTAEAVNVAHAVGVRAWFLANRAGEPADLVDCI
AGTIVKDNEEDRARLRRYFEQRVATHKEAHWQAYYQARHRLP
>SEQF1516_EDU86243.1 tyrosine-protein kinase wzc [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEKVKQHAAPVTGSDEIDIGRLVGTVIEARWWVIGITAVFALCAVVYTFFATPIYSADALVQIEQSSGNSLVQDIGSAL
ANKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVSKNTFPIFGAGWDRLMGRQNETVKVTTFNRPKEMEDQVFTLNVLDNK
NYTLSSDGGFSARGQAGQILKKEGVTLMVEAIHARPGSEFTVTKYSTLGMINQLQNSLTVTENGKDAGVLSLTYTGEDRE
QIRDILNSIARNYQEQNIERKSAEASKSLAFLAQQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQL
NELTFKEAEISKLYTKVHPAYRTLLEKRQALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKEQELKITE
ASTVGDVRIVDPAITQPGVLKPKKGLIILGAIILGLMLSIVGVLLRSLFNRGIESPQVLEEHGISVYASIPLSEWQKARD
SVKTIKGIKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLL
IDCDMRKGYTHELLGTNNVNGLSEILIGQGDITTAAKPTSIAKFDLIPRGQVPPNPSELLMSERFAELVNWASKNYDLVL
IDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFEQNGIPVKGVILNSIFRRASAYQDYGYYEYEYKSDAK
>SEQF1516_EDU86244.1 DNA-3-methyladenine glycosylase 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYTLNWQPPYDWSWMLGFLAARAVSGVETVADDYYARSLAVGEYRGVVTAIPDIARHTLHINLSADLEPVAAECLAKMSR
LLDLQCNPQIVNGALGKLGAARPGLRLPGSVDAFEQGVRAILGQLVSVAMAAKLTAKVVQLYGERLDDFPEYICFPTPQR
LAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRWTANYFALRGWQAKDVFLPDDYL
IKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEGWQPDEA
>SEQF1516_EDU86245.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIKNKMLLGALLLVTSAAWAAPATAGSTNTSGISKYELSSFIADFKHYKPGDTVPEMYRTDEYNIKQWQLRNLPAPDAG
THWTYMGGAYVLISDTDGKIIKAYDGEIFYHR
>SEQF1516_EDU86246.1 peptidase, U32 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFNHENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIR
DLKPVVEMGPDALIMSDPGLIMLVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKYEPIPVQNVEPTLGIGAPTDKVF
MIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVERLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDT
SLLETLEGLAHRGYTEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELMTPQGNINF
TLEHMENAKGEAMPVAPGDGYTVWLPVPQDLELNYALLMRNFSGETTRNPHGK
>SEQF1516_EDU86247.1 multidrug resistance protein MdtB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQF
GQMSGLKQMSSQSSGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPM
TQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGPSRAVTLSA
NDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESL
PKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMA
LTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAI
LISAVVSLTLTPMMCARMLSQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKG
FFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDRVQKV
IARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQATSLDALSTWVPQLMEKLQQLPQISDVSSDWQDKGLVAYV
NVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKIEQ
RFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIV
LGILYESFIHPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPRDAIYQA
CLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTKSRFARHEEEA
>SEQF1516_EDU86248.1 GDP-fucose synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKQRIFIAGHQGMVGSAITRRLKQRDDVELVLRTRDELNLLDSSAVLDFFSSQKIDQVYLAAAKVGGILANSSYPADFI
YENIMIEANVIHAAHKNNVNKLLFLGSSCIYPKLAHQPIMEDELLQGKLEPTNEPYAIAKIAGIKLCESYNRQFGRDYRS
VMPTNLYGPNDNFHPSNSHVIPALLRRFHDAVENNSPNVVVWGSGTPKREFLHVDDMASASIYVMEMPYDIWQKNTKVML
SHINIGTGIDCTICELAETIAKVVGYKGHITFDTTKPDGAPRKLLDVTLLHQLGWNHKITLHKGLENTYNWFLENQLQYR
G
>SEQF1516_EDU86249.1 fimbrial usher protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRMTPLASAIVALLLGIEAHAAEETFDTHFMMGGMKGEQVTNLRLDDNQPLPGQYDIDIYVNKQWRGKYEIIVKDNPHE
TCLTREIVKRLGINSDNFARENQCLTFEQLVQGGSYSWDIGIFRLDLAVPQAWVEELENGYVPPENWERGINAFYTSYYV
SQYYSDYKASGNSKSTYVRFNSGLNLLGWQLHSDASFSKTDNNPGEWKSNTLYLEHGFSQILGTLRIGDMYTSADIFDSV
RFTGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVTIEQNGFVVYQKEVPPGPFSISDLQLAGGGADLDVSVKEADGSVT
TYLVPYAAVPNMLQPGVSKYDFAAGRSHIEGASKQSDFVQAGYQYGFNNLLTLYGGTMVANNYYAFTLGTGWNTRIGAIS
VDATKSHSKQDNGDVFDGQSYQIAYNKFLSQTSTRFGLAAWRYSSRDYRTFNDYVWANNKDNYRRDKNDVYDIADYYQND
FGRKNSFSANMSQSLPEGWGSVSLSTLWRDYWGRSGSSKDYQLSYSNNWRRISYTLAASQAYDENHAEEKRFNIFISIPF
DWGDDVTTPRRQIYMSNSTTFDDQGFASNNTGLSGTVGNRDQFNYGINLSHQHQGNETTAGANLTWTAPAATVNGSYSQS
STYRQVGASVSGGLVAWSGGVNLANRLSETFAVMHAPGIKDAYVNGQKYRTTNCNGVVVYDGLTPYRENHLMMDVSQSDS
ETELRGNRKMTAPYRGAVVLVDFDTDQRKPWFIKALRSDGQPLTFGYEVNDMHGHNIGVVGQGSQIFIRTNEIPPAVNVA
IDKQQGLSCTITFGKEIDESKNYICR
>SEQF1516_EDU86250.1 glycosyl transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIALNSDGFYEWGGGIDFIKYILSILETKPEICIDILLPRNDIHSLIREKAFPFKSILKAILKRERPRWISLNRFNEQY
YRDAFTQNNIETNLTFIKSKSSAFYSYFDSSDCDVILPCMRVPSGNLNKKAWIGYIYDFQHCYYPSFFSKREIDQRNVFF
KLMLNCANNIIVNAHSVITDANKYVGNYSAKLHSLPFSPCPQLKWFADYSGNIAKYNIDKDYFIICNQFWKHKDHATAFR
AFKIYTEYNPDVYLVCTGATQDYRFPGYFNELMVLAKKLGIESKIKILGHIPKLEQIELIKNCIAVIQPTLFEGGPGGGV
TFDAIALGKKVILSDIDVNKEVNCGDVYFFQAKNHYSLNDAMVKADESKIFYEPTTLIELGLKRRNACADFLLDVVKQEI
ESRS
>SEQF1516_EDU86251.1 O antigen polymerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSAAKLIFLFLFTLYSLQLYGVIIDDRITNFDTKVLTSIIIIFQIFFVLLFYLTIINERKQQKKFIVNWELKLILVFLF
VTIEIAAVVLFLKEGIPIFDDDPGGAKLRIAEGNGLYIRYIKYFGNIVVFALIILYDEHKFKQRTIIFVYFTTIALFGYR
SELVLLILQYILITNILSKDNRNPKIKRIIGYFLLVGVVCSLFYLSLGQDGEQNDSYNNMLRIINRLTIEQVESVPYVVS
ESIKNDFFPTPELEKELKAIINRIQGIKHQDLFYGERLHKQVFGDMGANFLSVTTYGAELLVFFGFLCVFIIPLGIYIPF
YLLKRMKKTHSSINCAFYSYIIMILLQYLVAGNASAFFFGPFLSVLIMCTPLILLHDTLKRLSRNENISYNCDL
>SEQF1516_EDU86252.1 DNA-binding response regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVHKLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFL
TAFDEYAIKAFEEHAFDYLLKPIDEARLEKTLARLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRM
SGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILRNGLTVPVSRRYLKSLKEAIGL
>SEQF1516_EDU86253.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSWRLVYASAVGTSHISADLPCQDACQMQVAWLNDQQPLLVMFLADGAGSVSQGGEGAMLAINEAMAYVSQKVQHGEFGL
NDILATDIVLTVRQRLFAEAEAKELAVRDFACTFLGLISSANGTLIMQIGDGGVVVDFGHGLQLPLTPMVGEYANMTHFI
TDEDVVSRLETFTSTERAHKVAAFTDGIQRLALNMLDNSPHVPFFTPFFNGLAAATQEQLDLLPELLKQFLSSPAVNERT
DDDKTLTLALWLP
>SEQF1516_EDU86254.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGWFELSKSSDSQFRFVLKAGNGETILTSELYTSKASAEKGIASVRSNSPQEERYEKKTASNGKFYFNLKAANHQIIGS
SQMYATAQSRETGIASVKANGTSQTVKDNT
>SEQF1516_EDU86255.1 YohL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAAIRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDV
VLKVLDSYIK
>SEQF1516_EDU86256.1 mannose-1-phosphate guanylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQSKLYPVVMAGGSGSRLWPLSRVLYPKQFLCLKGDLTMLQTTICRLNGVECESPVVICNEQHRFIVAEQLRQLNKLTE
NIILEPAGRNTAPAIALAALAAKRHSPENDPLMLVLAADHVIADEDAFRAAVRNAMPYAEAGKLVTFGIVPDLPETGYGY
IRRGEVSAGEQDTVAFEVAQFVEKPNLETAQAYVASGEYYWNSGMFLFRAGRYLEELKKYRPDILDACEKAMSAVDPDLD
FIRVDEDAFLACPEESVDYAVMERTADAVVVPMDAGWSDVGSWSSLWEISAHTAEGNVCHGDVINHKTENSYVYAESGLV
TTVGVKDLVVVQTKDAVLIADRNAVQDVKKVVEQIKADGRHEHRVHREVYRPWGKYDSIDAGDRYQVKRITVKPGEGLSV
QMHHHRAEHWVVVAGTAKVTIDGDIKLLGENESIYIPLGATHCLENPGKIPLDLIEVRSGSYLEEDDVVRFADRYGRV
>SEQF1516_EDU86257.1 hypothetical protein ECH7EC4501_2410 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAGDGIQTRSGNIIPRMVSKLTLSLRPGRHQKIAHTLIGKQHL
>SEQF1516_EDU86258.1 mrp protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAWMDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGA
KAIDWKLSHNIATLKRVKNQPGINGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDYLVLDMPPGTGDIQLTLAQNIPV
TGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVENMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLR
EDLDKGTPTVISRPESEFTAIYRQLADRVAAQLYWQGEVIPGEISFRAV
>SEQF1516_EDU86259.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSLRPELLELTPQALTALSNAGFVKRSLKELENGNVPEISHENGALIATFSDGVRTQLANGQALKEAQCTCGASGMCRH
RVMLVLSYQRLCATTRPTEKEEEWQPAIWLEELATLPDATRKRAQVLVAKGITIELFCAPGEIPSARLPMSDVRFYSRSS
IRFARCDCIEGTLCEHVVLAVQAFVEAKTQQAEFTHLIWQMRSEHVTSSDDPFASEEGNACRQYVQQLSQALWLGGISQP
LIHYEAAFSRAQQAAERCNWRWVSESLRQLRASVDAFHARASHYHAGECLRQLAALNSRLNCAQEMARRDSVGEVPPVPW
RTVVGSGIAGEAKLDHLRLVSLGMRCWQDIEHYGLRIWFTDPDTGSILHLSRSWPRSEQENSPAATRRLFSFQAGALAGG
QIVSQAAKRSADGELLLATRNRLSSVVPLSPDAWRMLSAPLRQPGIVALREYLRQRPPSCIRPLNQVDNLFILPVAECIS
LGWDSSRQTLDAQVISGEGEDNLLTLSLPASASAPYAVERMAALLQQTDDPVCLVSGFVSFVDGQLTLEPQVMMTKTRAW
ALDAETAPVVASLPSASVLPVPSTAHQLLMRCQALLIQLLHNGWRYQEQSAIGQAELLANDLTAVGFYRLAHVLGQFRNT
ESEARVEAMNNGVLLCEQLFPLLQQQG
>SEQF1516_EDU86260.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAFNKLFSLVVASVLVFSLAGCGDKEESKKFSANLNGTEIAITYVYKGDKVLKQSSETKIQFASIGATTKEDAAKTLEP
LSAKYKNIAGVEEKLTYTDTYAQENVTIDMEKVDFKALQGISGINVSAEDAKKGITMAQMELVMKAAGFKEVK
>SEQF1516_EDU86261.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGEGEMKKIAAISLISVFLMSGCAVHNDETSIGKFGLAYKSNIQRKLDNQYYTEAEASLARGRISGAENIVKNDAAHFCV
TQGKKMQIVDLKTEGAGLHGVARLTFKCGE
>SEQF1516_EDU86262.1 transcriptional regulator, GntR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAENQSTVENAKEKLDRWLKDGITTPGGKLPSERELGELLGIKRMTLRQALLNLEAESKIFRKDRKGWFVTQPRFNYSPE
LSASFQRAAIEQGREPSWGFTEKNRTSDIPETLAPLIAVTPSTELYRITGWGALEGHKVFYHETYINPEVAPGFIEQLEN
HSFSAVWEKCYQKETVVKKLIFKPVRMPGDISKYLGGSAGMPAILIEKHRADQQGNIVQIDIEYWRFEAVDLIINL
>SEQF1516_EDU86263.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAHHQMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDV
QDKGLGTLMAMTLESVARQEGVKRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQ
LQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWGLIWLMLRERHLGGTIILADAHI
RYSKPISGKPHAVADLGALSGDLDRLARGRKARVQMQVEIFGDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE
>SEQF1516_EDU86264.1 CDP-diacylglycerol pyrophosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLPNQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMP
TYRINGTESPLLTDPSTPNFFWLAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLAN
ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQSDNSFVLLATQRNLLTLNRASAE
EIQDHQCEILR
>SEQF1516_EDU86265.1 met repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRRQVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKE
RSDEIPEAAKEIMREMGINPETWEY
>SEQF1516_EDU86266.1 hypothetical protein ECH7EC4501_4296 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLVSTLSRPIYIRLLRVQGVGVIFLCGRGRKGPELAQFPSIQEGFVTEYHNVGVCVLIWLRESEKNTAKRNRKCDKYHR
CSSN
>SEQF1516_EDU86267.1 ferredoxin--NADP(+) reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADWVTGKVTKVQNWTDALFSLTVHAPVHPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLA
ALKPGDEVQVVSEAAGFFVLDEVPDCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEK
RYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESAIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG
HMTAEHYW
>SEQF1516_EDU86268.1 hypothetical protein ECH7EC4501_4257 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVPNRHWNTVSISTDKTIDIRSEDNSVFISAFRLPAGRSADDSLEELKKMQRDNLKDQYNEETFQFHDCNAKHFTCKYQ
DVLINFDGQQKRTISVYLEDTPRAVGIIALMEPDTADKYRQQAMEIMLSAKNTVK
>SEQF1516_EDU86269.1 sensor histidine kinase CpxA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQRQGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAP
PGQRLLLVTTEGRVIGAERSEMQIIRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLL
FDRPLLLLIVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEFLAAGASFNQMVTALERMMTSQQ
RLLSDISHELRTPLTRLQLGTALLRRRSGESKELERIETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDN
AAFEAEQMGKSLTVNFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVSPEDREQIF
RPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIWLPLYKRS
>SEQF1516_EDU86270.1 universal stress protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYKHIGVAISGNEEDALLVNKALELARHNDAHLTLIHIDDGLSELYPGIYFPATEDILQLLKNKSDNKLYKLTKNIQWP
KTKLRIERGEMPETLLEIMQKEQCDLLVCGHHHSFINRLMPAYRGMINKLSADLLIVPFIDK
>SEQF1516_EDU86271.1 nitrogen regulation protein NR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATGTQPDAGQILNSLINSILLIDDNLAIHYANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIELMQESLEAGQGFTDNE
VTLVIDGRSHILSVTAQRMPDGMILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
DPSLLEYTKVIIEQADRLRNLVDRLLGPQLPGTRVTESIHKVAERVVTLVSMELPDNVRLIRDYDPSLPELAHDPDQIEQ
VLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGERYRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIAR
NLIDQHSGKIEFTSWPGHTEFSVYLPIRK
>SEQF1516_EDU86272.1 transcriptional activator RhaR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFCNNANLLNVFVRHIANNQFRSLAEVATVAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDFCELVIVWRGNGL
HVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFSASAGQPHWRLGSMGMAQARQVI
GQLEHESSQHVPFANEMAELLFGQLVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLR
QQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRHLNSQKD
>SEQF1516_EDU86273.1 formate C-acetyltransferase 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRAKATAYILEHVEISIRDEELIAGNRTVKPRAGIMSPE
MDPYWLLKELGQFPTRPQDRFAISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIID
YPRLLNHGLGELVAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAASCTDAQRREELLTIAEISRHNAEHK
PQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYMLPFYQASLTQGEDPAFLKELLESLWVKCNDIVLLRSTSSARYFA
GFPTGYTALLGGLTENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRLGTGIPQIFNDEVVVPA
FLNRGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHENEGNAALTYEGLLEQIRAKISHYITLMVEGS
NICDIGHRDWAPVPLLSSFISDCLEKGRDITDGGARYNFSGVQGIGIANLSDSLHALKGMVFDQQRLSFDELLSVLKANF
ATPEGEKVRARLINRFEKYGNDIDEVGNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVPLGSVVGATPDGRFAGE
QLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVKFTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNAD
TLREAQQRPQDYAGLVVRVAGYSAFFVELSKEIQDDIIRRTAHQL
>SEQF1516_EDU86274.1 hypothetical protein ECH7EC4501_4256 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNIILLFIYLLLIAVNHFRYKFLLSGNAGEMILYFANVFFNPLALSFIIATIICITIKKRSSRSFIRGTCWLMGLFLIY
SSYTVWERHSIWDYTFPEPGITVTVPSKQWVANIVKQGPTLVTRDAHAILAIVAFSQNELGVHSIEELTATQNGTAEMHV
CDVQGFACAYQEGVQTMSDGKVRHAIFMTLLDNTNLIQLVAAIDPDYLDEYQEEVMKMMLSARQ
>SEQF1516_EDU86275.1 TonB-dependent vitamin B12 receptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLAPTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGS
GQLSSIFIRGTNASHVLVLIDGVRLNLAGGSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEI
SAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQPDNDGFLSKTLYGALEHNFTDAWSGFVRG
YGYDNRTNYDAYYSPGSPLVDTRKLYSQSWDAGLRYNGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQW
ANNIIIGHGNVGAGVDWQKQSTAPGTAYVKDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQTSAGWEFI
EGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVNWRISGYRNDVSDLIDYDDHTLKYYNEGKAR
IKGVEATANFDTGPLTHTVSYDYVDARNAITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVK
MGGVSLWDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF
>SEQF1516_EDU86276.1 hypothetical protein ECH7EC4501_4294 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNFIILFINKMRVVAFSFFIYYVHSLIYIFIRQLNEKEFIIFRYYSRHHGPRSDGL
>SEQF1516_EDU86277.1 MOSC domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRYPVDVYTGKIQAYPEGKPSAIAKIQVDGELMLTELGLEGDEQAEKKVHGGPDRALCHYPREHYLYWAREFPEQAELFV
APAFGENLSTDGLTESNVYIGDIFRWGEALIQVSQPRSPCYKLNYHFDISDIAQLMQNTGKVGWLYSVIAPGKVSADAPL
ELVSRVSDVTVQEAAAIAWHMPFDDDQYHRLLSAAGLSKSWTRTMQKRRLSGKIEDFSRRLWGK
>SEQF1516_EDU86278.1 aspartokinase/homoserine dehydrogenase II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDMMVVSAAGSTTNQLINWLKLSQTDRLSAHQVQQTLRR
YQCDLISGLLPAEEADSLISAFVSDLERLAALLDSGINDAVYAEVVGHGEVWSARLMSAVLNQQGLPAAWLDAREFLRAE
RAAQPQVDEGLSYPLLQQLLVQHPGKRLVVTGFISRNNAGETVLLGRNGSDYSATQIGALAGVSRVTIWSDVAGVYSADP
RKVKDACLLPLLRLDEASELARLAAPVLHARTLQPVSGSEIDLQLRCSYTPDQGSTRIERVLASGTGARIVTSHDDVCLI
EFQVPTSQDFKLAHKEIDQILKRAQVRPLAVGVHNDRQLLQFCYTSEVADSALKILDEAGLPGELRLRQGLALVAMVGAG
VTRNPLHCHRFWQQLKGQPVEFTWQSDDGISLVAVLRTGPTESLIQGLHQSVFRAEKRIGLVLFGKGNIGSRWLELFARE
QSTLSARTGFEFVLAGVVDSRRSLLSYDGLDASRALAFFNDEAVEQDEESLFLWMRAHPYDDLVVLDVTASQQLADQYLD
FASHGFHVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNATVGAGLPINHTVRDLIDSGDTILSISGIFSGTLSWLFLQ
FDGSVPFTELVDQAWQQGLTEPDPRDDLSGKDVMRKLVILAREAGYNIEPDQVRVESLVPAHCEGGSIDHFFENGDELNE
QMVQRLEAAREMGLVLRYVARFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGAIQ
SDINRLAQLL
>SEQF1516_EDU86279.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQNAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV
>SEQF1516_EDU86280.1 N-acylglucosamine 2-epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKWFNTLSHNRWLEQETDRIFDFGKNSVVPTGFGWLGNKGQIKEEMGTHLWITARMLHVYSVAAAMGRPGAYSLVDHGIK
AMNGALRDKKYGGWYACVNDEGVVDASKQGYQHFFALLGAASAVTTGHPEARKLLDYTIEIIEKYFWSEEEQMCLESWDE
AFSKTEEYRGGNANMHAVEAFLIVYDVTHDKKWLDRAIRVASVIIHDVARNNHYRVNEHFDTQWNPLPDYNKDNPAHRFR
AFGGTPGHWIEWGRLMLHIHAALEARCEQPPAWLLEDAKGLFNATVRDAWAPDGADGIVYTVDWEGKPVVRERVRWPIVE
AMGTAYALYTVTGDRQYETWYQTWWDYCIKYLMDYENGSWWQELDADNKVTTKVWDGKQDIYHLLHCLVIPRIPLAPGLA
PAVAAGLLDINAK
>SEQF1516_EDU86281.1 transcriptional regulatory protein CpxR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDSIDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTAR
GSELDRVLGLELGADDYLPKPFNDRELVARIRAILRRSHWSEQQQNNDNGSPTLEVDALVLNPGRQEASFDGQTLELTGT
EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWFKTLRGRGYLMVSAS
>SEQF1516_EDU86282.1 5,10-methylenetetrahydrofolate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNSIDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKDR
TGLEAAPHLTCIDATPDELRTIARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAK
SAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFKQAKKFADMTNVRIPAWMAQMFD
GLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYTLNRAEMSYAICHTLGVRPGL
>SEQF1516_EDU86283.1 periplasmic protein CpxP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSHMFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELE
TMHRLVTAENFDENAVRAQAEKMANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLS
SSNSRSQ
>SEQF1516_EDU86284.1 tRNA-processing ribonuclease BN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSLLSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFL
PATGDVIQRYIEQFVANSNKMTAVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAI
SSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAALLFEAGKKGFALYITMFPSYQL
IYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYRKLKQAAEQEEDDEP
>SEQF1516_EDU86285.1 phosphoenolpyruvate carboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKSSRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLN
LANTAEQYHSISPKGEAASNPEVIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQ
LDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVPNYLRELNEQLEENLGYKLPVEF
VPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKATDLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLR
SRLMATQAWLEARLKGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVRIDIRQEST
RHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAETREVLDTCQVIAEAPQGSIAAYVISMAKTP
SDVLAVHLLLKEAGIGFAMPVAPLFETLDDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQA
QDALIKTCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLPEITVSSLSLYTGAILE
ANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYFRSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFA
WTQNRLMLPAWLGAGTALQKVVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKTLWPLGKELRN
LQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKEGQEPDPRVEQALMVTIAGIAAGMR
NTG
>SEQF1516_EDU86286.1 glycoporin RafY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKSTLSLAIGLLLACSTGMAKTQHLMLEQRMALLEERLEAAEMRAAKAESQVKQLQTQQAAEIREIKAAQGNTPVNGQA
TAESAKKNATSPNLLLSGYGDLKIYGDVEFNMDAESNHGLLAMTNADVNSDPTNEQWNLNGRILLGFDGMRKMDNGYFAG
FSAQPLGDMHGSVNIDDAVFFFGKENDWKVKVGRFEAYDMFPLNQDTFVEHSGNTANDLYDDGSGYIYMMKEGRGRSNAG
GNFLVSKQLDNWYFELNTLLEDGTSLYNDGNYHGRDMEQQKNVAYLRPVIAWSPTEEFTVSAAMEANVVNNAYGYTDSKG
NFVDQSDRTGYGMSMTWNGLKTDPDNGIVVNLNTAYLDANNEKDFTAGINALWKRFELGYIYAHNKIDEFSGVVCDNDCC
IDDEGTYTIHTIHASYQFANVMDMENFNIYLGTYYSILDSDGDKKHGDDTDDRYGARVRFKYFF
>SEQF1516_EDU86287.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPSSPSRSKGHAKARRKTREELNQEARDRKRQKKRRGHAPGSRAAGGNNTSGSKGQNAPKDPRIGSKTPIPLGVTEKVT
KQHKPKSEKPMLSPQAELELLETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQED
MMRLLRGN
>SEQF1516_EDU86288.1 HTH-type transcriptional activator RhaS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHGTGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLC
LTNVLYRSPDRFQFLAGLNQLLPQELDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKS
SLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLMKARHLLRHSEASVT
DIAYHCGFSDSNHFSTLFRREFNWSPRDIRQGRDGFLQ
>SEQF1516_EDU86289.1 glycerol uptake facilitator protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEISVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFAC
FDKRKVIPFIVSQVAGAFCAAALVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILM
GLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAGWGNVAFTGGRDIPYFLVPLFGP
IVGAIVGAFAYRKLIGRHLPCDICVVEEKETTTPSEQKASL
>SEQF1516_EDU86290.1 PTS system, fructose family, IIB component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYLVAVTACVSGVAHTYMAAERLEKLCLLEKWGVSIETQGALGTENRLADEDIRRADVALLITDIELAGAERFEHCRYV
QCSIYAFLREPQQVMSAVRKVLSAPQQTHLILE
>SEQF1516_EDU86291.1 tRNA (uracil-5-)-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHYRMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAA
SELINQLMTAMIAGVRNNPVLRHKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTK
IALDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELYCGNGNFSLALARNFDRVLATEI
AKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNGVREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRIL
YISCNPETLCKNLETLSQTHKVERLALFDQFPYTHHMECGVLLTAK
>SEQF1516_EDU86292.1 putative transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAAGKSNPLAISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTALRCIFGALVLFIVLLLRGRGMRPTPFKYTLAIALLQT
CGMVGLAQWALVSGGAGKVAILSYTMPFWVVIFAAVFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAMLAILS
GVSWGASAIVAKRLYARHPRVDLLSLTSWQMLYAALVMSVVALLVPQREIDWQPTVFWALAYSAILATALAWSLWLFVLK
NLPASIASLSTLAVPVCGVLFSWWLLGENPGAVEGSGIVLIVLALALVSRKKKEAVSVKRI
>SEQF1516_EDU86293.1 aminopeptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGSFVARKGNKGPKVAVVGHMDEVGFMVTHIDESGFLRF
TTIGGWWNQSMLNHRVTIRTHKGVKIPGVIGSVAPHALTEKQKQQPLSFDEMFIDIGANSREEAKKRGAEIGDFISPEAN
FACWGEDKIVGKALDNRIGCAMMAELLQTVNNPGITLYGVGSVEEEVGLRGAQTSAEHTKPDVVIVLDTAVAGDVPGIDN
IKYPLKLGNGPGLMLFDKRYLPNQKLVAALKNCAAHNGLPLQFSTMKTGATDGGRYNVMGGGRPVVALCLPTRYLHANSG
MISKADYDALLTLIRDFLTTLTAEKVNAFSQFRQVD
>SEQF1516_EDU86294.1 hypothetical protein ECH7EC4501_4283 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGHWQPGKDERDDVHNLLNCGDVMLTAFPENSRCILKNRRFLRGFPSKI
>SEQF1516_EDU86295.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKDVVDKCSTKGCAIDIGTVIDNDNCTSKFSRFFATREEAESFMTKLKELAAAASSADEGASVAYKIKDLEGQVELDAAF
TFSCQAEMIIFELSLRSLA
>SEQF1516_EDU86296.1 PTS system, fructose family, IIA component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAALTASCIDLNIQGNGAYSVLKQLATMALQNGFITDSHQFLQTLLLREKMHSTGFGSGVAVPHGKSTCVKQPFVLFARK
AQAIDWKASDGEDVNCWICLGVPQSGEEDQVKIIGTLCRKIIHQEFIHQLQQGDTDQVLALLNQTLSS
>SEQF1516_EDU86297.1 L-rhamnose isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRADLE
QAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWID
HCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLDPAHHIDAVESKLFGIGAESYTVG
SNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDR
VHIGLDFFDASINRIAAWIIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAG
SEWLESVRAYEKETLSRRG
>SEQF1516_EDU86298.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSLAGIDMGRIILDLSNEVIKQLDDLEVQRNLPRTELLREAVDQYLVNQSQTVRTSAFGIWQGCEEDGVEYQRKLREEW
>SEQF1516_EDU86299.1 sugar (Glycoside-Pentoside-Hexuronide) transporter family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDHNPLTLKLNLREKIAYGMGDVGSNLMLSIGTLYLLKFYTDELGMPAYYGGIIFLVAKFFTAFTDMLTGFLLDSRKNI
GPKGKFRPFILYAAVPAALIATLQFIATTFSLPVKTTIATALFMMFGLSYSLMNCSYGAMIPAITKNPNERAQLAAYRQG
GATIGLLICTVAFIPLQSLFSDSTVGYACAALMFSIGGFIFMMLCYRGVKEHYVDTAPTGHKASILKSFCAIFRNPPLLV
LCIANLCTLAAFNIKLAIQVYYTQYVLNDINLLSWMGFFSMGCILVGVLLVPLTVKCFGKKQVYLAGMVLWAVGDILNYF
WGSNSFTFVMFSCIAFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFFRKISAALAGFLPGIMLTQIGYVPN
IAQSDATLQGLRQLIFIWPCALAIIAALTMGFFYTLNEKRFALIIEEINQRKNKEMATEEKTASVTL
>SEQF1516_EDU86300.1 rhamnulokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHSQNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGID
TWGVDFVLLDQQGQRVGLPVAYRDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLM
PDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTAS
AVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIS
ATQALPACRFIINPNDDRFINPETMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGEDFSQLHIV
GGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSTTANLTTFTPNPDSEIAHYVARIHS
TRQTKELCA
>SEQF1516_EDU86301.1 N-acetyl-gamma-glutamyl-phosphate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNTLIVGASGYAGAELVTCVNRHPHMNITALTVSAQSNDAGKLISDLHPQLKGIVDLPLQPMSDISEFSPGVDVVFLAT
AHEVSHDLAPQFLDAGCVVFDLSGAFRVNDATFYEKYYGFTHQYPELLEQAAYGLAEWCGNKLKEANLIAVPGCYPTAAQ
LALKPLIDADLLDLNQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEIATHLGADVIFTPHLGNFPRGIL
ETITCRLKPGVTQAQVAQALQQAYAHKPLVRLYDKGVPALKNVVGLPFCDIGFAVQGEHLIIVATEDNLLKGAAAQAVQC
ANIRFGYAETQSLI
>SEQF1516_EDU86302.1 rhamnulose-1-phosphate aldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIALYHDNFHPQPRYIPLSQPMPLLANTPFIVTGSGKFFR
NVQLDPAANLGVVKVDSDGAGYHILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAV
FTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAEVLVK
VYSMGGMKQTISREELIALGQRFGVTPLASALAL
>SEQF1516_EDU86303.1 hippuricase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEHYIRGFEEELREIRHQIHENPELGLQEFKTSALVAEKLRQWGYEVEQGLATTGIVATLKVGDGEKSIGLRADMDALP
IYENSGKPWASKHPGLMHACGHDGHTTILLGAARYFAETRRFNGTLRLIFQPAEEMINGGEIMVKEGLFDHFPCDVIFGM
HNMPGLPVGKFYFQPGALMASMDQFHITVRGCGGHGAIPHKAIDPVLVAAHITTALQSIVSRNVDPLEAAVITVGSIVAG
EAANVIPDSAEMKISVRSLSRDTRQLLLTRIPALAQAQAASFGATAEVTHVNGTPVLVNDEEMARFAWQVACKTFGEDRA
EFGIKPLMGSEDFSFMLEAQPKGGFLLFGNGDVGEGSCMVHNPGYDFNDASLVPASSYWGALVEAWLQ
>SEQF1516_EDU86304.1 PTS system, fructose family, IIB component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIGLENELTAEDVASADMVILTKDIGIKFEERFAGKTIV
RVNISDAVKRADAIMSKIEAHLAQTA
>SEQF1516_EDU86305.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKASLALVSLLTAFTSYSLKSPAIPPTVVQIQANTNLAIADGARQQIGSTLFYDPAYVQLTYPGGDVPQERGVCSDVVIR
ALRSQKVDLQKLVHEDMAKNFAEYPQKWQLKRPDSNIDHRRVPNLETWFTRHDKTRPISKNPSDYQAGDIVSWRLDNGLA
HIGVVSDGFARDGTPLVIHNIGAGAQEEDVLFSWRMVGHYRYFVK
>SEQF1516_EDU86306.1 glycyl-radical enzyme activating protein family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSSAGQRISCNVVETRRNDVARIFNIQRYSLNDGEGIRTVVFFKGCPHLCPWCANPESISGKIQTVRREAKCLHCAKCL
RDADECPSGAFERIGRDISLDALEREVMKDDIFFRTSGGGVTLSGGEVLMQAEFATRFLQRLRLWGVSCAIETAGDAPAS
KLLPLAKLCDEVLFDLKIMDATQARDVVKMNLPRVLENLRLLVSEGVNVIPRLPLIPGFTLSRENMQQALDVLIPLKIRQ
IHLLPFHQYGEPKYRLLGKTWSMKEVPAPSSADVTTMREMAERAGFQVTVGG
>SEQF1516_EDU86307.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKTTSTETLFYFYRIIVFILKLITKKPPPLAMVHFLS
>SEQF1516_EDU86308.1 formate dehydrogenase-O, gamma subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLMQIMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNL
INRDDIFWAKNIRKIVVNEEVGDTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVAL
IVVIMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE
>SEQF1516_EDU86309.1 L-rhamnose 1-epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKARNLLFATVEIESEERWNAVASTEICQRWWKYM
TDVMPANPDNSPVSSELQEVFYLP
>SEQF1516_EDU86310.1 major facilitator superfamily [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAIVNETVSVKKKPSGRRVIFASAFGNALEFFDFGVYNFFVVYISTLFFPPSADKNVALLLAFATFGVSFFMRPLGGII
VGAWADRFGRKPAMVFTIALMSLGTLMIGIAPTYETAGYWGTATLVLARLIQGVAAGGEVGASMSLLVESAPANRRGFYS
SWSLATQGLATTFGGVVALGLSAWLPFATGSETVMAEWGWRVPFFIGVLLAPVGCWLRLSLENDVPEPAHNKKAAASESA
FSLLMQHKATIANGILLAIGSTVATYISLFYYGTWAAKYLGMNQNYSHAAMLLAGVITFVGALLVGMLCDSVGRKKLILI
SRVMVLICSWPSFWLLVNYPSPGMLLTVVFVMVSFTTLGGVPVMLLISELLPKRIRALGFALVYSIGVAIFGGFAQYFAT
QSIVLLDSLTAPAWYLGGGTLLSMLALLYVKEPAKELQ
>SEQF1516_EDU86311.1 protein RhsA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVTFGHPVNPLLGAKVLPGETDIALPGPLPFILSRTYSS
YRTKTPAPVGSLGPGWKMPADIRLQLRDNTLILSDNGGRSLYFEHLFPGEDGYSRSESLWLVRGGVAKLDEGHRLAALWQ
ALPEELRLSPHRYLATNSPQGPWWLLGWCERVPEADEVLPAPLPPYRVLTGLVDRFGRTQTFHREAAGEFSGEITGVTDG
AGRHFRLVLTTQAQRAEEARQQAISGGTEPSAFPDTLPGYTEYGRDNGIRLSAVWLTHDPEYPENLPAAPLVRYGWTPRG
ELAVVYDRSGKQVRSFTYDDKYRGRMVAHRHTGRPEIRYRYDSDGRVTEQLNPAGLSYTYQYEKDRITITDSLNRREVLH
TQGEGGLKRVVKKEHADGSVTQSQFDAVGRLRAQTDAAGRTTEYSPDVVTGLITRITTPDGRASAFYYNHHSQLTSATGP
DGLEIRREYDEWGRLIQETAPDGDITRYRYDNPHSDLPCATEDATGSRKTMTWSRYGQLLSFTDCSGYVTRYDHDRFGQM
TAVHREEGLSQYRAYDSRGQLIAVKDTQGHETRYEYNAAGDLTTVIAPDGSRNGTQYDAWGKAICTTQGGLTRSMEYDAA
GRVIRLTSENGSHTTFRYDVLDRLIQETGFDGRTQRYHHDLTGKLIRSEDEGLVTHWHYDEADRLTHRTVKGETAERWQY
DERGWLTDISHISEGHRVTVHYGYDEKGRLTGERQTVHHPQTEALLWQHETRHAYNAQGLANRCIPDSLPAVEWLTYGSG
WLAGMKLGDTPLVDFTRDRLHRKTLRRFGRYELTTAYTPAGQLQSQHLNSLQYDRDYTWNDNGELIRISSPRQTRSYSYS
DSGRLTGVHTTAANLDIRIPYATDPAGNRLPDPELHPDSTLSMWPDNRIARDAHYLYRYDRHGRLTEKTDLIPEGVIRTD
DERTHRYHYDSQHRLVHYTRTQYEEPLVESRYLYDPLGRRVAKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQND
RTRIQTIYQPGSFTPLIRVETATGELAKTQRRSLADALQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLA
SCGLTVAQMQSQMDPVYTPARKIHLYHCDHRGLPLALISKEGATEWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEES
GLYYNRHRYYDPLQGRYITQDPIGLKGGWNLYTYPLSPVNGMDPLGLYEFKSKNIDDIGIFALAMCNGESINENKEYGGL
ICKKQGEYFPMNPISSNDNDSVDLRNIKCPEGSERVGDYHTHGFYSDDKGNKVTKENDVYDSLNFSSKDLTNSYMNGMGK
KECSSYLGTPNNTYLKYNPKAKGNGVTIIRQGSN
>SEQF1516_EDU86312.1 superoxide dismutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALESLPEFANLPVEELITKLDQLPADKKTVLRNNAGGHA
NHSLFWKGLKKGTTLQGDLKAAIERDFGSVDNFKAEFEKAAASRFGSGWAWLVLKGDKLAVVSTANQDSPLMGEAISGAS
GFPILGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK
>SEQF1516_EDU86313.1 oxygen-independent coproporphyrinogen III oxidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQAVARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQH
KADQYLDALEQEIVHRAPLFAGRHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLR
AEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDLIYGLPKQTPESFAFTLKRVAELNPDRLSVF
NYAHLPTIFAAQRKIKDADLPSPQQKLDILQETIAFLTQSGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTD
LLGMGVSAISMIGDCYAQNQKELKQYYQQVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEKQWDLHFADYF
AEDLKLLAPLAKDGLVDVDEKGIQVTAKGRLLIRNICMCFDTYLRQKARMQQFSRVI
>SEQF1516_EDU86314.1 GTP-binding protein TypA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEKLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQERVMDSNDLEKERGITILAKNTAIKWNDYRINIVDTPGHAD
FGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAYGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF
PIVYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPFQMQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTII
DSEGKTRNAKVGKVLGHLGLERIETDLAEAGDIVAITGLGELNISDTVCDTQNVEALPALSVDEPTVSMFFCVNTSPFCG
KEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREIDGRKQEPY
ENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMTMTSGTGLLYSTFSHYDDVRPGEV
GQRQNGVLISNGQGKAVAFALFGLQDRGKLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVVLVPP
IRMTLEQALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRAPKDD
>SEQF1516_EDU86315.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALGLTGCDDKKAETETPLPANSQPAAPAPEAKPTEAPVAKADAKPETPAQPLVDEQAVFDEKMDVYIKCYNKLQIPVQR
SLARYADWLKDFKQGPTGKESTVYGIYGISESNLAECEKGVKSAVALTPALQPIDGVAVSYIDAAVALGNTINEMDKYYT
QENYKDDAFAKGKTLHQTFLKNLEAFEPVAESYHAAIQEINDKRQLAELKNIEEREGKTFHYYSLAVMISAKQINNLISQ
EKFDVDAAMKKVSELETLVAQAKEADKGGMNFSFINSADQYQLETKKYVRRVRDKVPYSDWDKEHLQDANTSWMVEDSFP
RALREYNEMVDDYNSLR
>SEQF1516_EDU86316.1 cation-efflux pump FieF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALVDSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAES
LAALAQSMFISGSALFLFLTGIQHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMM
NGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEIIDIVTSWPGVSGAHDLRTRQSG
PTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFPGSDVIIHQDPCSVVPREGKRSMLS
>SEQF1516_EDU86317.1 putative domain of unknown function [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFFTLFSPDGVMLETNVVCIVIALMFLYTFVGICAGFGGGLTTMPLVTLMLPVKMATPLSVIVGTATALYATWLSRKET
DWRSAMVLIIFSFLGIPVGLYALSYLPDHFMKVGLGGFLILYSFYSMFIPRLPIYDRSWIAAPIGAVAGALGAAFSTNGP
PMVIYGMLRNLGPAAFRGTLNAFFTANNIAVIGGLATSGILTVSIFKLVLFCIPTMILGSLVGQYVHKRISVKVFRVMVF
LLLIASGSMLIKGALGIPAAAALLPPFTLLVILQLVFGKKVAAIRQAEASK
>SEQF1516_EDU86318.1 putative sulfatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTNGIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWA
ASLAALCYYVIYGQEFSQSVLFVMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
YGLILHPIAMNMFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNENNALPPLANFKDESGNEPRTLV
LVIGESTQRGRMSLYGYPRETTPELNALHKTDPNLTVFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQA
GYKTFWITNQQTMTARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQEVLKDPAPKKLIIVHLLGTHIKYKYRY
PENQGKFDGNTDHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAADPNGFLVYFSDHGEEVYDTPPHKTQGRNED
NPTRHMYTIPFLLWTSEKWQATHPRDFSQDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKENTRWIGNPYKKN
ALIDYDTLPYGDQVGNQ
>SEQF1516_EDU86319.1 kinase, PfkB family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATAAVAAARLGAQVDFIGRVGDDDTGNSLLAELESWGVN
TRYTKRYKQAKSSQSAIMVDAKGERIIINYPSPDLLPDAEWLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLD
GDITPQDISELVALSDHAAFSEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGCDWLENGGRQHQPAFKVDVVDTT
GAGDVFHGALAVVLATGGDLAESVRFASGVAASKCTRPGGRAGIPDCDQTRSFLSLFV
>SEQF1516_EDU86320.1 transcriptional regulator, DeoR/GntR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRDIRKLSEQGLITRHHGGAGRASSVVNTAFEQREVSQT
EEKKAIAEAVADYIPDGSTIFITIGTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPS
AASFVADFRADYLVTSVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHASAAVEIGNVAQVTALFTDELPP
AALKSRLQDSQIEIILPQEDA
>SEQF1516_EDU86321.1 cell division protein FtsN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVLVTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPE
ERWRYIKELESRQPGVRAPTEPSAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQ
QLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHTTAQSKPQQAAPVTRAADAPKPTA
EKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSKITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG
>SEQF1516_EDU86322.1 PTS system, fructose-specfic family, IIBC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMESSLRIVAITNCPAGIAHTYMVAEALEQKARSLGHTIKVETQGSSGVENRLSSEEIAAADYVILATGRGLSGDDRAR
FAGKKVYEIAISQALKNIDQIFSELPTNSQLFAADSGVKLGKQEVQSGSVMSHLMAGVSAALPFVIGGGILVALANMLVQ
FGLPYTDMSKGAPSFTWVVESIGYLGFTFMIPIMGAYIASSIADKPAFAPAFLVCYLANDKALLGTQSGAGFLGAVVLGL
AIGYFVFWFRKVRLGKALQPLLGSMLIPFVTLLVFGVLTYYVIGPVMSDLMGGLLHFLNTIPPSMKFAAAFLVGAMLAFD
MGGPINKTAWFFCFSLLEKHIYDWYAIVGVVPVAAGLATFIAPKLFTRQEKEAASSAIVVGATVATEPAIPYALAAPLPM
ITANTLAGGITGVLVIAFGIKRLAPGLGIFDPLIGLMSPVGSFYLVLAIGLALNISFIIVLKGLWLRRKAKAAQQELVHE
H
>SEQF1516_EDU86323.1 soluble pyridine nucleotide transhydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGGCTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLR
SSFADILNHADNVINQQTRMRQGFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTH
PRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQEMSDSLSYHFWNSGVVIRHNEEY
EKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTDSLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLAS
AAYDQGRIAAQALVKGEATAHLIEDIPTGIYTIPEISSVGKTEQLLTAMKVPYEVGRAQFKHLARAQIVGMNVGTLKILF
HRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTMAEAYRVAALNGLNRLF
>SEQF1516_EDU86324.1 putative inner membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQANQDRGTLLLALVAGLSINGTFAALFSSIVPFSVFPIISLVLTVYCLHQRYLNRTMPVGLPGLAAACFILGVLLYST
VVRAEYPDIGSNFFPAVLSVIMVFWIGAKMRNRKQEVAE
>SEQF1516_EDU86325.1 argininosuccinate lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESD
AEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRA
QPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLS
AAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKD
MQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGK
PLEELPLTELQKFSPVIGEDVYPILSLQSCLDKRAAKGGVSPQQVARAIAFARARLG
>SEQF1516_EDU86326.1 ATP-dependent protease HslV [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELA
KDWRTDRMLRKLEALLAVADETASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDIC
IYTNHFHTIEELSYKA
>SEQF1516_EDU86327.1 nitrogen regulation protein NR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFMQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALASKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLP
VIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAISHYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRL
SRSSISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLF
LDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVQEGKFREDLFHRLNVIRVHLPPLRERRED
IPRLARHFLQVAARELGVEAKLLHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFESTVAESTSQM
QPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME
>SEQF1516_EDU86328.1 2-keto-3-deoxygluconate transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQIKRLIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMITGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVT
KIAVAWVVAAIASRIIPEHGVEVGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGT
AGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTVIAQTGLLGILLGVAVIIVTGIP
LIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKI
EILGTVK
>SEQF1516_EDU86329.1 heat shock protein HslVU, ATPase subunit HslU [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEELRHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIK
VEATKFTEVGYVGKEVDSIIRDLTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFR
KKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKIKDAMKLLIEEEAAKLVNPEELK
QDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREGVQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIP
ELQGRLPIRVELQALTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGARRLHTVLE
RLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL
>SEQF1516_EDU86330.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLVLFSLAGKNLLDIQTAAFCLVCLLWPTAAVTVKRLHDRGRSGAWAFLMI
VAWMLLAGNWAILPGVWQWAVGRFVPTLILVMMLIDLGAFVGTQGENKYGKDTQDVKYKADNKSSN
>SEQF1516_EDU86331.1 fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRELAIEFSRVTESAALAGYKWLGRGDKNTADGAAVNAMRIMLNQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGRGDAV
DIAVDPIEGTRMTAMGQANSLAVLAVGDKGCFLNAPDMYMEKLIVGPGAKGTIDLNLPLADNLRNVAAALGKPLSELTVT
ILAKPRHDAVIAEMQQLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSAAVIRALDGDMNGRLLARHDVKG
DNEENRRIGEQELARCKAMGIESGKVLRLGDMARSDNVIFSATGITKGDLLEGISRKGNIATTETLLIRGKSRTIRRIQS
IHYLDRKDPEMQVHIL
>SEQF1516_EDU86332.1 putative PTS system, IIA component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFTLNGKARISASGSAGYQLEIFERRSFFQLLQKHDNDD
RLLALLLLNTFTPRAQLASALNLPETWVAERLPRLKQRYERTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLA
GVTRDNLQHLSTACDNQHRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIVEHNGLFLGDNAVRTLTGLIEKQ
HQQAQVISADHVLGLLQRVPGLASLNIIDTQLVENITGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLR
EQLDIPLFDSDLIGLYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLHCRVIIARSLSELVAIREEIEPLLIIN
NSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGSFHYSNVRGESWQHITRQICAQLVAQHHITA
DEAQRIIAREGEGENLIVNRLAIPHCWSEQERRFRGFFITLAQPVEVNNEVINHVLIACAAADARHELKIFSYLASVLCQ
HPAEVIAGLTGYEAFMELLHKG
>SEQF1516_EDU86333.1 aldose-1-epimerase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQITNMHCSGQTVSLAAGDYHATIVTVGAGLAELTFQGCHLVIPHKPEEMPLAHLGKVLIPWPNRIANGCYRYQGQEYQL
PINEHGSKAAIHGLLAWRDWQISELTATSVTLTAFLPPSYGYPFMLASQVVYSLNARTGLSVEIASQNIGTVTAPYGVGI
HPYLTCNLTSVDEYLFQLPANQVYAVDEHANPTTLHHVDELDLNFTQAKKIAATKIDHTFKTANDLWEITITHPQQALSV
SLCSDQPWVQIYSGEKLQRQGLAVEPMSCPPNAFNSGLDLLLLEPGKTHRLFFNIYGQHN
>SEQF1516_EDU86334.1 ribbon-helix-helix protein, copG family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQQFPVRKAKGGRQKGEVVGVDDQCKEHKE
>SEQF1516_EDU86335.1 glycerol kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPGWVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGI
TNQRETTIVWEKETGKPIYNAIVWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGE
LLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEVRRSSEVYGQTNIGGKGGTRIPI
SGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNTGEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDE
MKLINDAYDSEYFATKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDVLEAMQADS
GIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGLAVGFWQNLDELQEKAVIEREFRPGIETTER
NYRYAGWKKAVKRAMAWEEHDE
>SEQF1516_EDU86336.1 AP endonuclease, family 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTINNARKILQRVDTLPLYLHAYAFHLNMRLERVLPADLLDIASENNLRGVKIHVLDGERFSLGNMDDKELSAFGDKAR
RLNLDIHIETSASDKASIDEAVAIALKTGASSVRFYPRYEGNLRDVLSIIANDIAYVREAYQDSGLTFTIEQHEDLKSHE
LVSLVKESEMESLSLLFDFANMINANEHPIDALKTMAPHITQVHIKDALIVKEQGGLGHKACISGQGDMPFKELLTHLIC
LGDEEPQVTAYGLEEEVDYYAPAFRFEDEDDNPWIPYRQMSETPLPEKHLLDERLRKEKEDAINQINHVRNVLQQIKQEA
SHLLNH
>SEQF1516_EDU86337.1 3-hydroxyisobutyrate dehydrogenase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAIAFIGLGQMGSPMASNLLQQGHQLRVFDVNAEAVRHLVDKGATPAANPAQAAKDAEFIITMLPNGDLVRSVLFGENG
VCESLSTDALVIDMSTIHPLQTDKLIADMQAKGFNMMDVPVGRTSANAITGTLLLLAGGTAEQVERATPILMAMGSELIN
AGGPGMGIRVKLINNYMSIALNALSAEAAVLCEALNLPFDVAVKVMSGTAAGKGHFTTSWPNKVLSGDLSPAFMIDLAHK
DLGIALDVANQLHVPMPLGAASREVYSQARAAGRGRQDWSAILEQVRVSAGMTAKVKM
>SEQF1516_EDU86338.1 hypothetical protein ECH7EC4501_4330 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTPSDGVSGGYGVPADARFGSSAGCAATFVAATTAVV
>SEQF1516_EDU86339.1 fatty acid biosynthesis regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFILWYSASSTFGKDSDIVMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGIAPTSFYRHFRDVDELGLT
MVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGNNPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLEL
ENHMPRAFTEAQAEAMVTIVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE
>SEQF1516_EDU86340.1 catalase/peroxidase HPI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVDLLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKA
LLTESQPWWPADWGSYAGLFIRMAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLGATEMGLIYVNPEGPDHSGEPLS
AAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAGPTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQ
TPTQWSNYFFENLFKYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRRFLNDPQAF
NEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDIIDLKFAIADSGLSVSELVSVAWASASTFRG
GDKRGGANGARLALMPQRDWDVNAAAVRALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDAR
QDQTDIEMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFDGSKNGVFTDRVGVLSN
DFFVNLLDMRYEWKATDESKELFEGRDRETGEVKYTASRADLVFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNL
DRFDLL
>SEQF1516_EDU86341.1 formate dehydrogenase accessory protein FdhD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNITGVRQIELWRRDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSC
NGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTH
AAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAE
RCNLTLVGFCKPGRATVYTHPQRLSN
>SEQF1516_EDU86342.1 primosomal protein N' [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVAHVALPVPLPRTFDYLLPEGMAVKAGCRVRVPFGKQQERIGVVVSVSDVSELPLNELKAVVEVLDSEPVFTHSVWRL
LLWAADYYHHPIGDVLFHALPILLRQGRPAANAPMWYWFATEQGHAVDLNSLKRSPKQQQALAALRQGKIWRDQVATLEF
NDAALQALRKKGLCDLASETPEFSDWRTNYAVSGERLRLNTEQATAVGAIHSAADTFSAWLLAGVTGSGKTEVYLSVLEN
VLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVLHSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVID
EEHDSSYKQQEGWRYHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYRLLRLTRRAGNARPAIQHVLDLKGQKVQ
AGLAPALITRMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDHYYTLHQAQQHLRCHHCDSQRPVPRQCPSCG
STHLVPVGLGTEQLEQTLAPLFPGVPISRIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVD
GALFSADFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDAFAEQALAERRMMQLPPWTSHVIVR
AEDHNNQHAPLFLQQLRNLILSSPLADDKLWVLGPVPALAPKRGGRWRWQILLQHPSRVRLQHIINGTLALINTIPDSRK
VKWVLDVDPIEG
>SEQF1516_EDU86343.1 glycosyl hydrolase, family 31 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDTPRPQLPDFEFHQNNDSFTLHFRQRLILTHSKDNPCLWIGSGIADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWL
IHFSRGSDISATLNISADDQGRLLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALWEDKATLRFECADTYISLLEKLT
ALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMRNAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRI
KQWNKEGVQFLAYINPYVASDKDLCEEAAKRGYLAKDVAGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKKNMIELGCG
GWMADFGEYLPTDTYLHNGISAEIMHNAWPALWAKCNYEALEETGKLGEILFFMRAGSTGSQKYSTMMWAGDQNVDWSLD
DGLASVVPAALSLAMTGHGLHHSDIGGYTTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFAR
MTTVFTTLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQTYSLKYQYLLGRDILVAPVHEEGRSDWTLYLPEDNWVHAWT
GETFHGGEITVEAPIGKPPVFYRADSEWAALFASLKNI
>SEQF1516_EDU86344.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTKKKWALFSLLTLCGGTIYKLPSLKDAFYIPMQEYFHLTNGQIGNAMSVNSFVTTVGFFLSIYFADKLPRRYTMSFSL
IATGLLGVYLTTMPGYWGILFVWALFGVTCDMMNWPVLLKSVSRLGNSEQQGRLFGFFETGRGIVDTVVAFSALAVFTWF
GSGLLGFKAGIWFYSLIVIAVGITIFFVLNDKEEAPSVEVKKEDGASQNTSMTSVLKDKTIWLIAFNVFFVYAVYCGLTF
FIPFLKNIYLLPVALVGAYGIINQYCLKMIGGPIGGMISDKILKSPSKYLCYTFIISTAALVLLIMLPHESMPVYLGMAC
TLGFGAIVFTQRAVFFAPIGEAKIAENKTGAAMALGSFIGYAPAMFCFSLYGYILDLNPGIIGYKIVFGIMACFAFCGAV
VSVMLVKRISQRKKEMLAAEA
>SEQF1516_EDU86345.1 multi-phosphoryl transfer protein 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALIVEFICELPNGVHARPASHVETLCNTFSSQIEWHNLRTDRKGNAKSALALIGTDTLAGDNCQLLISGADEQEAHQRL
SQWLRDEFPHCDAPLAEVKSDELEPLPVSLTNLNPQIIRARTVCSGSAGGILTPISSLDLNALGNLPAAKDVDAEQSALE
NGLTLVLKNIEFRLLDSDGATSAILEAHRSLAGDTSLHEHLLAGVSAGLSCAEAIVASANHFCEEFSRSSSSYLQERALD
VRDVCFQLLQQIYGEQRFPAPGKLTQPAICMADELTPSQFLELDKNHLKGLLLKSGGTTSHTVILARSFNIPTLVGVDID
ALTPWQHQTIYIDGNAGAIVVEPGEAVARYYQQEARVQDALREQQRVWLTQQARTADGIRIEIAANIAHSVEAQAAFGNG
AEGVGLFRTEMLYMDRTSAPGESELYNIFCQALESANGRSIIVRTMDIGGDKPVDYLNIPAEANPFLGYRAVRIYEEYAS
LFTTQLRSILRASAHGSLKIMIPMISSMEEILWVKEKLAEAKQQLRNEHIPFDEKIQLGIMLEVPSVMFIIDQCCEEIDF
FSIGSNDLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVLPLLVGLGLDELSMSAP
SIPAAKARMAQLDSRECRKLLNQAMACRTSLEVEHLLAQFRMTQQDAPLVTAECITLESDWRSKEEVLKGMTDNLLLAGR
CRYPRKLEADLWAREAVFSTGLGFSFAIPHSKSEHIEQSTISVARLQAPVRWGDDEAQFIIMLTLNKHAAGDQHMRIFSR
LARRIMHEEFRNALVNAASADAIASLLQHELEL
>SEQF1516_EDU86346.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYHDVSYLLSRLINGPLSLRQIYFASSNGPVPDLAYQVDFPRLEIVLEGEFVDTGAGATLVPGDVLYVAAGGWNFPQWQA
PATTFSVLFGKQQLGFSVVQWDGKQYQNLAKQHVARRGPRIGSFLLQTLNEMQMQPQEQQTARLIVASLLSHCRDLLGSQ
IQTASRSQALFEAIRDYIDERYASALTRESVAQAFYISPNYLSHLFQKTGAIGFNEYLNHTRLEHAKTLLKGYDLKVKEV
AHACGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLTEKPTTPE
>SEQF1516_EDU86347.1 6-phosphofructokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLGLYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDE
NIRAVAIENLKKRGIDALVVIGGDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSS
HQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAIVAITEHMCDVDELAHFIEKETG
RETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLLLAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY
>SEQF1516_EDU86348.1 formate dehydrogenase accessory protein FdhE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTAR
IKEASAQGKPPLDIHVLPRDKHWQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFI
WAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSGKLHY
WSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAVADDLASLVLDARMEQEGYARSSINPFLFPGEGE
>SEQF1516_EDU86349.1 glycerol dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDRIIQSPGKYIQGADVINRLGEYLKPLAERWLVVGDKFVLGFAQSTVEKSFKDAGLVVEIAPFGGECSQNEIDRLRGIA
ETAQCGAILGIGGGKTLDTAKALAHFMGVPVAIAPTIASTDAPCSALSVIYTDEGEFDRYLLLPNNPNMVIVDTKIVAGA
PARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLLEEGEKAMLAAEQHVVTPALERVIEANTYL
SGVGFESGGLAAAHAVHNGLTAIPDAHHYYHGEKVAFGTLTQLVLENSPVEEIETVAALSHAVGLPITLAQLDIKEDVPA
KMRIVAEAACAEGETIHNMPGGATPDQVYAALLVADQYGQRFLQEWE
>SEQF1516_EDU86350.1 glutamate racemase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLVFDSGVGGLSVYDEIRHLLPDLHYIYAFDNVAFPYGEKSEAFIVERVVAIVTAVQERYPLALAVVACNTASTVSLPAL
REKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEMLGSAEMVELAEAKLHGEDVSLDAL
KRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVLPEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPEA
EQLLPVLQRYGFETLEKLAVLG
>SEQF1516_EDU86351.1 hypothetical protein ECH7EC4501_4249 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVAAVSCFFAFTLTPRLARQAYYIHVYFTSATFLADSA
>SEQF1516_EDU86352.1 fructose-6-phosphate aldolase 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELYLDTANVAEVERLAHIFPIAGVTTNPSIIAASKESIWEVLPRLQKAIGDEGILFAQTMSRDAQGMVEEAKRLRDAIP
GIVVKIPVTSEGLAAIKILKKEGITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQALLEMHAPES
MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTTHL
>SEQF1516_EDU86353.1 deoxyribose-phosphate aldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKYTINDITRASGGFAMLAVDQREAMRMMFAAAGAPAPVADSVLTDFKVNAAKTLSPYASAILVDQQFCYRQVVEQNAI
AKSCAMIVAADEFIPGNGIPVDSVVIDRKINPLQIKQDGGKALKLLVLWRSDEDAQQRLDMVKEFNELCHSHGLVSIIEP
VVRPPRRGDKFDREQAIIDAAKELGDSGADLYKVEMPLYGKGPQQELLSASQRLNDHINMPWVILSSGVDEKLFPRAVRV
AMTAGASGFLAGRAVWASVVGLPDNELMLRDVCAPKLQQLGDIVDEMMAKRR
>SEQF1516_EDU86354.1 formate dehydrogenase-O, iron-sulfur subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKACQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVM
RFSEVEQNDKLEWLIRKDGCMHCSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFDIPRLNPEDNRVYKC
TLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAGVGGTHVMYVLHHADKPNLYHGL
PENPEISETVKFWKGIWKPLAAVGFAATFAASIFHYVGVGPNHADEEENNLHEEKDEERK
>SEQF1516_EDU86355.1 triosephosphate isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPEMYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSA
AMLKDIGAQYIIIGHSERRTYHKESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFE
GAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNAAELFAQPDIDGALVGGASLKAD
AFAVIVKAAEAAKQA
>SEQF1516_EDU86356.1 sulfate-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKWGVGLTFLLAATSVMAKDIQLLNVSYDPTRELYEQYNKAFSAHWKQQTGDNVVIRQSHGGSGKQATSVINGIEADVV
TLALAYDVDAIAERGRIDKEWIKRLPDNSAPYTSTIVFLVRKGNPKQIHDWNDLIKLGVSVITPNPKSSGGARWNYLAAW
GYALHHNNNDQAKAQDFVRALYKNVEVLDSGARGSTNTFVERGIGDVLISWENEALLAANELGKDKFEIVTPSESILAEP
TVSVVDKVVEKKGTKEVAEAYLKYLYSPEGQEIAAKNYYRPRDAEVAKKYENAFPKLKLFTIDEEFGGWTKAQKEHFANG
GTFDQISKR
>SEQF1516_EDU86357.1 sugar transporter family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFYTDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSR
RKIGPKGKFRPFILYASFPVTLLAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAW
RQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPANPAQKPGLLQSFRAIAG
NRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDPILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVLG
DLLNYFFSGGSVSFVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGFFPGWMLTQ
IGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRIVEEIEARKRTA
>SEQF1516_EDU86358.1 acetylornithine deacetylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFKDLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGH
TDTVPFDDGRWTRDPFTLTEHDGKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTAL
RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQLRDNLKERYHYEAFTVPYPTLN
LGHIHGGDASNRICAWCELHMDIRPLPGMTLNELNGLLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKL
LGAKTEVVNYCTEAPFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH
>SEQF1516_EDU86359.1 hydrogen peroxide-inducible genes activator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELGVMLLERTSRKVLFTQAGMLLVDQARTVLREVKVLKE
MASQQGETMSGPLHIGLIPTVGPYLLPHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCVILALVKESEAFIEVPL
FDEPMLLAIYEDHPWANRECVPMADLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTHFRATSLETLRNMVAAGSGITLL
PALAVPPERKRDGVVYLPCIKPEPRRTIGLVYRPGSPLRSRYEQLAEAIRARMDGHFDKVLKQAV
>SEQF1516_EDU86360.1 regulator of ribonuclease activity A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFEDNGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELAR
LAVQNEWEGLVIYGAVRQVDDLEELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDI
E
>SEQF1516_EDU86361.1 D-tyrosyl-tRNA(Tyr) deacylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANRLCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFT
LAADTERGMRPSFSKGASPDRAEALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV
>SEQF1516_EDU86362.1 1,4-dihydroxy-2-naphthoate octaprenyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARIMTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPLVALLALITAGLLQILSNLANDYGDAVKGSDKP
DRIGPLRGMQKGVITQQEMKRALIITVVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDI
SVLVFFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLVVRLGEVNARRYHACLLMGS
LVCLALFNLFSLHSLWGWLFLLAAPLLVKQARYVMREMDPVAMRPMLERTVKGALLTNLLFVVGIFLSQWAA
>SEQF1516_EDU86363.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIRLLILSLLVSVPAFAWQPQTGDIIFQISRSSQSKAIQLATHSDYSHTGMLVMRNKKPYVFEAVGPVKYTPLKQWIAH
GEKGKYVVRRVEGGLSVEQQQKLAQTAKRYLGKPYDFSFSWSDDRQYCSEVVWKVYQNALGMRVGEQQKLKEFDLSNPLV
QAKLKERYGKNIPLEETVVSPQAVFDAPQLTTVAKEWPLFSW
>SEQF1516_EDU86364.1 acetylglutamate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGGGCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALA
GTANKTLLAWAKKHQIAAVGLFLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVNA
DQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKVNAALDAARTLGRPVDIASWRHAE
QLPALFNGMPMGTRILA
>SEQF1516_EDU86365.1 O-succinylhomoserine (thiol)-lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAI
HLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAENPKLVLVESPSNPLLRVVDIAKIC
HLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYL
LLRGLRTLVPRMELAQRNAKAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSL
FTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG
>SEQF1516_EDU86366.1 hypothetical protein ECH7EC4501_4240 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEKPKGVNRKMTNDGEEKSGKMKKLQDGKKKKIRYAKQTGLQI
>SEQF1516_EDU86367.1 glutamine synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPF
FADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWN
SSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYK
YVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLSKNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSY
KRLVPGYEAPVMLAYSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDL
PPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV
>SEQF1516_EDU86368.1 phosphatase YihX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYIFDLGNVIVDIDFNRVLGTWSDLTRIPLATLKKSFHMGEAFHQHERGEISDEAFAEALCHEMALPLSYEQFSHGWQA
VFVALRPEVIAIMHKLREQGHRVVVLSNTNRLHTTFWPEEYPEIRDAADHIYLSQDLGMRKPEARIYQHVLQAEGFSPSD
TVFFDDNADNIEGANQLGITSILVKDKTTIPDYFAKVLC
>SEQF1516_EDU86369.1 50S ribosomal protein L31 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFFTGKQRDVATGGRVDRFNKRFNIPGSK
>SEQF1516_EDU86370.1 transcriptional repressor CytR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEV
TAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELELPTVHIDNLTA
AFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLLDLPQPPTAVFC
HSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHVGSGSRLMDCEL
IIRGSTRALP
>SEQF1516_EDU86371.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPGCTLFFLLCSALTVTTTAHAQTPDTATTAPYLLAGAPTFDLSISQFREDFNSQNPSLPLNEFRAIDSSPDKANLTRA
ASKINENLYASTALERGTLKIKSIQMTWLPIQGPEQKAAKAKAQEYMAAVIRTLTPLMTKTQSQKKLQSLLTAGKNKRYY
TETEGALRYVVADNGEKGLTFAVEPIKLALSESLEGLNK
>SEQF1516_EDU86372.1 outer membrane porin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNINAIILLSSLTSASVFAGAYVENREAYNLASDQGEVMLRVGYNFDMGAGIMLTNTYTFQREDELKHGYNEIEGWYPL
FKPTDKLTIQPGGLINDKSIGSGGAVYLDVNYKFTPWFNLTVRNRFNHNNYSSTDLNGDLDNNDSYEIGNYWNFIITDKF
SYTFEPHYFYNINDFNSGNGTKHHWEITNTFRYRINEHWLPYIELRWLDRNVEPYHREQNQIRIGTKYFF
>SEQF1516_EDU86373.1 phage protein GP46 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADIAVVWDQGCGSLQLNGADLLTDNSLLTAVIISLFTDRRALDSDEIPDGTRDRRGWWGDSFRERPVGSRLWLLSREKT
LSSVVSRAQAYADEALAWLHKSGAATSVVCHAMRVGHARLSLSVKITLPDGSRHPMIFYADMKGE
>SEQF1516_EDU86374.1 geranyltranstransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGGKRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYS
LIHDDLPAMDDDDLRRGLPTCHVKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQAL
DLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLAFQVQDDILDVVGDTATLGKRQG
ADQQLGKSTYPALLGLEQARKKAQDLIDDARQSLKQLAEQSIDTSALEALADYIIQRNK
>SEQF1516_EDU86375.1 protein ThiJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSASALVCLAPGSEETEAVTTIDLLIRGGIKVTTASVASDGNLAITCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAE
CFRDSTLLVETVKQFHRSGRIVAAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWQDKRVVWDARVKLLTSQGPGT
AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE
>SEQF1516_EDU86376.1 exodeoxyribonuclease VII, small subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQLARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE
>SEQF1516_EDU86377.1 protein gp37 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITETEQAYIARIREYFGNELVSVDTHPGDWSDSVLRTMLINAPAIYVAWLGAGEGRTRGRLVSHWVFYVIGDMLNGREA
SRPGLYQIVARLIAVLNGFRTEKTSPLYFEKAVNGYTETQADSGAVMYALYFSCEEMIAPLTDTSSLDDFLRHYETFVEP
PGTPPFEAHIDLPGNTTTAVEPPEEL
>SEQF1516_EDU86378.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKTITKQPILFTDVPVADLRNSMKQDLNQNLIERLWNKIRDFFLDSDKQKAFKSIHKYINTLSVLNYNSALTPDPNFNI
DATSDLDSYLKLDFDRLSPKQKQTTLCCFWNKIASSLPEPYNSTIKHNIIFYKDGENLMIRGTISIVNEVVKTYSLPIEK
DDNGYYDFSGLYLAHSNISGKDPNKDPDIDFGIDMGNCNCSNVNFEHTYFYGVKFTNANCTNANFNNCRFKKCDLTNMNC
TGAILDNAMIYGKEKEPEMQYPEADQIIQRITYQKSDGNETKGMILTNCSCVKTTFNWADLSESDCQNVDFSEANLSNTI
LPDIVRMKGTKLYRTDLFNPILKTEAESTEEKDISPLAKIILDYIESDKNPESLNFEEKSTVIKIKQDIDNFIFYNQHLK
KIFNRAMNLQEKISRKKYNEFFKYIQAEAKQYFKDQYKLTKNDYLKKVPLTAQLIAKYKMDDQLDQLLVTREIQDEIKSK
IQDKIDELSKNLFNTMTETIENNFDDIFRQQSENMSNYYEFVD
>SEQF1516_EDU86379.1 recombination-associated exonuclease RdgC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMGWVPPMGSHSDALTHVANGQIVICARKEEKILPSPVI
KQALEAKIAKLEAEQARKLKKTEKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
LPVVPLSMANPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEEITNHIEAGKVVTKLALDWQQRI
QFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFDADFILMTGELAALIQNLIEGLGGEAQR
>SEQF1516_EDU86380.1 putative 3-hydroxyphenylpropionic acid transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQAFALDKMQMGWIFSAGILGLLPGALVGGMLADRYGRK
RILIGSVALFGLFSLATAIAWDFPSLVFARLMTGVGLGAALPNLIALTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGF
AGANLAWQTVFWVGGVVPLILVPLLMRWLPESAVFAGEKQAAPPLRALFAPETATATLLLWLCYFFTLLVVYMLINWLPL
LLVEQGFQPSQAAGVMFALQMGAASGTLMLGALMDKLRPVTMSLLIYSGMLASLLALGTVSSFNGMLLAGFVAGLFATGG
QSVLYALAPLFYSSQIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGILVAGLAVFILMSRRLRMQPC
ADA
>SEQF1516_EDU86381.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAVNNALPALIAGACMAALGIIAVLVAAIWGMHQKTQRLEDNNQVLVRERDEARQVLANQQHTLQLISQISEAATNEKQ
QNIQHSEGQQSVVRRSLAAVPAASAPVPDDVADRVRRAVCEIRACEAGADPR
>SEQF1516_EDU86382.1 phage transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYVIAKELIGAPGMPATTKGIRQALQRYVQGKSCCSRRRSGSKATEYSIDCLPEVTQQALRERYALQLMTQKADESPAPV
VTKARRSSDVVDAVEAYRGSPQLMVERLNALTENQRQVADARIAIVSEVMKVAQQPGFSCAKAIRFIVDNLARSQLDERI
VAMVETANAKKGNSRALSEITLKRWIAAFNKAQNAAERLLLLAPGKRQEIKAEDINWLPEFLAQYRQSNGRPMTEAYEDF
VAEWQHRHADEPYMLDIMPSYDTIRRAMKKLPEVVKQKGRVTGSEYRQLEGFTRRDWSRMPVNYVWIGDGHGMKLKCAHP
VHGRPFAPEVTFVIDGGTRFVVGWSLDLAENVFAVAGAIQHGIRHHGKPFLYYSDNGSGETADILDKEVVGILPRLGINH
PTGIAGNPQGRGIIERLNRTLPMRIARKYRTYFGKGADRETLRKTNRDLRSAFTALQQGKRLNARQQSAMRDLPSWSELI
DAIRDGVEWYNNRPHDELPVKPNGKHYSPAEFRKKRLAEEDTEIEWLSDVELRDMFRPMVERPVRRCEIRWLNNIYYAPE
LRDEHGRKVLISYDIHDAERITVRRLDGSVICEAVWDGNKREAFPVSAEYYKQQQRLKGMRKRAEEKIRDAEDEVVNVLE
HKPQEPWLENIYRPVGNTVAVQQPAIDDEPDEEYERNFQRGLQLLEAKLKENDPLA
>SEQF1516_EDU86383.1 protein gp28 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNAEELSPLLTNTVSTRKIDLAGEKALLGVDVPDSLDLPGDMPVFLDYQARWFEDESEVCIAEKSRRTGLTWAEAGRNV
ITAAKPKRRGGRNVFYVGSKQEMALEYISACALFSRAFNQLADADVYEQTFWDRDKKEEILTYMIRFPNSGFKIQALSSR
PSNLRGLQGDVVIDEAAFHESLDELLKAAMALTMWGARVRIISTHNGVDNLFNQYIQEAREGRKDYSVHRITLDDAIADG
LYRRICYVTGREWSPESEQKWRDDLYKNAPTREDADEEYGCIPKKSGGAYIPHALIEMAMLRDIPILTFEAPDDFISRAA
WLRESEVLTWCEEHLKPLLEALNPRSRFSFGEDFARTGDLSCFVLLEITESLAKREVFRVELRNLPYAQQEQVMMYILTR
VPALVGAAFDATGNGGYLAEAALLAFGPDIIDCVMLSPKWYGEWMPKLKAEFEDQNILVARHQTTLDDLRHVKVVNGIPQ
IDKGRTKDQNATAVNARRHGDFAVALCMANRASYMEGFILDESACQALPERSRAMEGGYRDDDEAYHEFDRGCW
>SEQF1516_EDU86384.1 phosphate starvation-inducible protein PsiF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKITLLVTLLFGLVFLTTVGAAERTLTPQQQRMTSCNQQATAQALKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMREC
NNQATQQSLKGDDRNKFMSACLKKAA
>SEQF1516_EDU86385.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDDSDRAQAVMERGSERALCNRLTRKRQAVDTPGRRVCADCGGEIPAARLVAVPDAIRCVNCQNIMEARHVGQHR
>SEQF1516_EDU86386.1 hypothetical protein ECH7EC4501_4033 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDKNGQSIEVSYIFTDTIDDKSDGKLCLKICNSCNQNDSSTHEYKIDHQQLKNHIRQLEEWALLEKFYDNNAYYSKRTK
QLEKKIADAGFITRKVKAENFNVKEFKDDIASMLCEQPPMRTHQISSSGYVSADKLHKLYKTNLEDAQRDLKTTPVDIDG
VSLKSITREKIAEEIAKKTAEIIAKQNAKSIEEKNIEKNKKQTNSEDNFVLKFSPEEINEMLLDYSDEEQKKLRPFFTSD
HIYCLFDAFSQGLHNVARNGSPRYAGLLRQIASKSAILQDFDQQLFWRTFTGGVLHRHISVKSEPEKTDVWRFSSQFDFP
HINENGELSRTVLMFEGVAESNFKDIANHSSECFSYRCYAAPLDANAKK
>SEQF1516_EDU86387.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMQSCGNKMNLFDSLNSARRLTELAGAVLERSKRYPQRFALKTTPPVGNVQGTGEIEITIQTNGLRRRVKATRISGCTV
YWEV
>SEQF1516_EDU86388.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVFYIPDIYGRFYLVNFDNVKVISLAENKECGDLLFEFNDRTRMVISAGLDREGATDVYSGICRSVGAKQVS
>SEQF1516_EDU86389.1 preprotein translocase, YajC subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQKRTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGY
IAIALNDTTEVVIKRDFVAAVLPKGTMKAL
>SEQF1516_EDU86390.1 1-deoxy-D-xylulose-5-phosphate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVSRSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGH
QAYPHKILTGRRDKIGTIRQKGGLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
FEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSGVPPIKELLKRTEEHIKGMVVPG
TLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPS
YSKIFGDWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIYSTFLQRAY
DQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPRGN
AVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPEAAKVAESLNATLVDMRFVKPLDETLILEMAASHEALVTVEENA
IMGGAGSGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA
>SEQF1516_EDU86391.1 AroM protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREEVMAEYAPEAGEDTILTLLNDNHLAHVSRRKVERDLQ
GVVEVLDNQGYDVIILMSTANISSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEELLTVQAQKWQILQKPPVFSL
GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFNQRHRDLLQKQLDVPVLLSNVLIARLAAELLV
>SEQF1516_EDU86392.1 cytochrome o ubiquinol oxidase, subunit III [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATDTLTHATVHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILFATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSS
ITYGMAAIAMYKNNKSQVISWLALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM
>SEQF1516_EDU86393.1 HNH endonuclease family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTVHHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEAD
QYGTTVIAGEDAQKDVGEAKYNPFADLKAMMNKKK
>SEQF1516_EDU86394.1 cytochrome o ubiquinol oxidase, subunit I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYLWKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMR
SQQALASAGEAGFLPPHHYDQIFTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAPGMTMFKMPVFTWASLCANVLII
ASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYINLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWAT
VCITVLSFIVWLHHFFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFSVGGMTGVL
LAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNETWGKRAFWFWIIGFFVAFMPLYALGFMGMT
RRLSQQIDPQFHTMLMIAASGAVLIALGILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHE
RDAFWEMKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIITWIVKSFDEDVDYYVPV
AEIEKLENQHFDEITKAGLKNGN
>SEQF1516_EDU86395.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQNDQQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKL
LKHPRQ
>SEQF1516_EDU86396.1 Fe(3+) ions import ATP-binding protein FbpC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQKNFVELRNVTKRFGSNTVIDNINLTIPQGQMVTLLGPSGCGKTTILRLVAGLEKPSEGQIFIDGEDVTCNQVNHLIP
TRVLVKGGEITCKILK
>SEQF1516_EDU86397.1 hypothetical protein ECH7EC4501_4039 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSERFLQPNRIQLPVKQAKKTAAQIRHGFFNRTDLKHHYGRIDG
>SEQF1516_EDU86398.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRFIRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAA
EAIEKGAAALNPRGERYTPATIRERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG
>SEQF1516_EDU86399.1 Mhp operon transcriptional activator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSINMQNNEQTEYKTVRGLTRGLMLLNMLNKLDGGASVGLLAELSGLHRTTVRRLLETLQEEGYVRRSPSDDSFRLTIKV
RQLSEGFRDEQWISALAAPLLGDLLREVVWPTDVSTLDVDAMVVRETTHRFSRLSFHRAMVGRRLPLLKTASGLTWLAFC
PEQERKELIEMLASRPGDDYQLAREPLKLEAILARARKEGYGQNYRGWDQEEKIASIAVPLRSEQRVIGCLNLVYMASAM
TIEQAAEKHLPALQRVAKQIEEGVESQAILVAGRRSGVHLR
>SEQF1516_EDU86400.1 protein mom [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGNRKQVTSRIISTPELIRYNDNIVGYGSRELRVETISCWLARLVIVNKHYSHRFVNNSYLHLGIFSERELVGVMQWGYA
LNPNSGARVVTGTQNREYMELNRLWLHDCMPRNSESRAISYALKLIRQLYPQVQWVQSFADERCGCLGVVYQASNFDYVG
SHESIFYELDGEWYHEICRNAIKRGGQRGEHLRANIDRASVHKFRQFRYIRFLNKRARKRLNTKLFKVQPYPKPQTVKTG
LKESE
>SEQF1516_EDU86401.1 putative transcription regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAETQMSMFGGDSEQLHALIDRLDDIPDDVLKKNWPRTLSELVEVTGAELQRQGIEPVLAGKLARKVAAAQAAYMGGRGY
YLPVGESLFAELRNNEIFSRWDRGEKIESLRRHYRMSETQIYTVIREQRRLHLARTQPPLF
>SEQF1516_EDU86402.1 transcriptional regulator, NrdR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVAELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVS
SDDVEMAINHIKSQLRATGEREVPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED
>SEQF1516_EDU86403.1 thiamine-monophosphate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAISTDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMG
ADPAWLTLALTLPDVDEAWLESFSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLISDLGHIVKASDCGARIDLALLP
FSDALSRHVVPEQALRWALSGGEDYELCFTVPELNRGALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYD
HFATP
>SEQF1516_EDU86404.1 hypothetical protein ECH7EC4501_4004 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSSADKACNVLVKKVRYLKDVRKITKMMNGKLIYSWLKWPCGEFFSLNYKLTKRIYFITFIYNKG
>SEQF1516_EDU86405.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNSSLLFWCLYITSFFGAFVITRWLCRKIICFFDKRHPVERAADALIQQAIVLYSGEFFCRITTRDGWHIMIIPPTHHA
RWDEAEKAFHVRKKVNTV
>SEQF1516_EDU86406.1 acetaldehyde dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKRKVAIIGSGNIGTDLMIKILRHDQHLEMAVMVGIDPQSDGLARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSA
GAHVKNDAALREAKPDIRLIDLTPAAIGPYCVPVVNLEENVDQLNVNMVTCGGQATIPMVAAVSRVVRVHYAEIIASIAS
KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEASQDDIEASINEMAEAVQAYVPGY
RLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEVEGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA
>SEQF1516_EDU86407.1 6,7-dimethyl-8-ribityllumazine synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQVKDENITVVWVPGAYELPLAAGALAKTGKYDAVIALG
TVIRGGTAHFEYVAGGASNGLAHVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA
>SEQF1516_EDU86408.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRVNHLSSLSFLAVLVLAGCSSQAPQPLKKGEKAIDVASVVRQKMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVL
AVAQQESNYQADPAVPGLSKIAWQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSGIFDDLISMVPM
GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLLNYPASYSAPIYRFADFNAGWYA
SRNAAFQNAVSKASGVKLALDGDLIRYDSKEPGKTELATRKLAAKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAEA
KTGKSLPREMLPGIQLESPKITRNLTTAWFAKRVDERRARCMKQ
>SEQF1516_EDU86409.1 bacteriophage Mu P protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSRVELYLGGEIFSGWLTVSVRRSLEHLAGSFELGVMMPGVRLPSSVRAGQSLELRIDGQPVITGWLDQVRQRISATRF
QITLSGRDKTGDLVDCSAIHPGSQWRNRTLEHIASDLCAPFGVTVRWQVNDATAARPFSTFTLENSETVADALTRAARHR
GVLVTSNAAGELVFTQAGSQRGDTLTLGENLLDLDHNVDHRLRHSEYRVRGHGRGGGHAGDALTAGTLAAPVGTVTDSAI
HRYRPKIVLADHAVDADGARQRAVREMRRAVARSVRLTATVRHWFRENGQLWDINLLTAVTAPRTGVEERDLLVCQVEFS
LDANHGETTRLILAPRDGFIVPAEPGNSGSGNAGDVDAFVRAQMKKQGIKFNDE
>SEQF1516_EDU86410.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAAVRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVD
DTIELVRAYLK
>SEQF1516_EDU86411.1 putative tail fiber assembly protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVRGKQLPAHKSAVVQKTDYLNKYMMILSFQQKQGEIMELINVKRYYPEHKPYGEDVQYFQSEDGRDFYESIPLFTKKYK
LCISPVTGIICSVAEDVSALYPAGFTVVEVDELPEGVNIDGNWQFSDGLISKVPVNWKTVAEKRRSSLLQEANETVDDWK
TELKLDMISDENKLQLTRWMAYIRQLKEMHFNDIASEGHYQAIPWPEKPE
>SEQF1516_EDU86412.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRPLTVAIIAVAGFSPFHLSVPFIVFSEKMAEKKRFHVIICAEKPGNVDSADGFSVTATHDYTAVIQADIVIIPYWGTIT
QKPPQKLLEALTTARDNGAQIVGLCLGTFVLGYAGLLKNKRAATHWEFEREFQARFPQTHLDINALYVDDDGIITSAGTA
AALDCCLYIVRQHFGSDYANHIARRMVVPPYRTGGQAQFIEQPVPKNTHDERINLLLDYLRQNIAQQHDLDSLAQRVMMS
RRTLTRHFMKATGSSIAEWLITERLRRSQELLGSSQLPVERIAAEVGFLSPVTWRQHFKSHFGVSPAEWRKTFRGMA
>SEQF1516_EDU86413.1 hypothetical protein ECH7EC4501_3997 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNNEDTFVILEGVISLRREENVLIGITQAPYIMGLADGLMKN
DIPYKLISEGNCTGYHLPAKQTITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY
>SEQF1516_EDU86414.1 host nuclease inhibitor protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKNLIAWAWSSGLIEFGYVLPEGALPIVAGKPATVRHVIEVMARHGRDEQEQLLVPGIPEAVTEEEAFNAMIRFCREVR
RRVSYPNRTRTRG
>SEQF1516_EDU86415.1 maltodextrin glucosidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDNEEMSVPMHKQRSQPQPGVTAWRAAIDLSSGQPRRRY
SFKLLWHDRQRWFTPQGFSRMPPARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILR
DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHNTQQL
GMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSI
VRHWLKAPWNMDGWRLDVVHMLGEAGGARNNLQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFP
LWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARFKTLLGREVARLPLAVVWLFTWPGVPCI
YYGDEVGLDGKNDPFCRKPFPWQVEKQDMALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINR
GEACEVVLPASPFLNVVQWQRKEGHGQLTDGILALPAISATVWMN
>SEQF1516_EDU86416.1 protein gp27 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKPTRGRVRKVDLLPDSIRKPLLEMLREKRLTQVQIREEINRLIREAGLPEEQQLSPAAISREASRNELIARNLRDLRE
QTKAMMAELGDKPTGETTALILEMSRALMYRRLRAATESLNSDSDVDMRLIKDILLSAQRAESAAERSIKREKEIRAAFA
EEMANAVTDELRGVDGMSEQLESRIKGILLGKA
>SEQF1516_EDU86417.1 binding-protein-dependent transport systems inner membrane component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQTLALHPVKKRDAIFLWVLLGWLAFVLLPSWSLDYGLLESTSDEILGAYGWSHFNISWLWYLLPSLLLVRPFRQATRE
QRSRHYFDAGWALLCMAFIVISATVAGRGLGYAAIVLFVELGAIMTLALTRLEWLGGDRFVIGSLIAIVALIGIFIVWPS
IAIFIPMFTNDAGELAPLAFMTVLSQAHIVQVIVNSIVLSIAVGIGCAFFGLVLAIYTTRIAKRSAIIGRIFSILPIVTP
PFVVGLGVTLMMGRSGYVTEFMVEWFGLTNTNWLYGFTGIWLAQVLAFTPMAFMILDGAIKTIHPSLEEASYTLRASRWQ
TFNGVFVPLLKPALANAFLIVVVQSLADFSNPLVLGGNFDVLATQIYFYITGSQLDYQAASTLGAFLLLFSLLVFCIQYM
WIGKRSYVTVSGKSYRGDVQPLPVTLVWSVVAILAIWIAFNALLYGSIFYGSFTVNWGVDYTLTLDNFIKLFGQGMSDGA
WPSLLDTLLYAGIAAPITAIFGLLIAWVVVRQQFKGKKTIEFTTMLCFAVPGTVAGVSYILAFNSAPVYLTGTAAIVIIS
MVMRNVPVGIRAGIAGLGQIDKSLDEASLSLRAGSLRTITHILLPLLRPAILSALIYSFVRAITTVSAIVFLVTPDTRVA
TAYILNRVEDGEYGVAIAYGSILIVVMLAIIFLFDWLIGEARISRSKAKNQA
>SEQF1516_EDU86418.1 hypothetical protein ECH7EC4501_4032 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKIIIFTMFEKKFLLFFISSIFSAEMFTKFSFPEMKSDLP
>SEQF1516_EDU86419.1 protein gp29 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLVVGRIIDLDGKPFSFDPEMQSAVLDIPQIASRYIEHPASGITPNRAAQCLRGAERGDLIAQSDLAADIEEKDTHLFAE
LGKRRLAIQSVPWSIEPPPNASANEKKDAEMLDEYLHSADWFDAMLFDATDAILKGYSCMEIEHGMLGKMHIIRAIRWRD
SGHFCLNPDDLSELRLRDGSHAGVAFQPFGWVVHQSRSRTGYGGATGLVRTLIWPFIFKNYSVRDLAEFLEVYGLPMKVG
KYPSGATSEQKSALMRAVMDIGRRTGGIIPAGMSLEFQVAANGQADPFETMISWGERSISKAILGGTLTTEAGDKGARSL
GEVHNEVRREIRDSDLRQLAATLNRDLVYPLYALNTAHAIDIRRLPRICFQTKEPGDITKITSAVMQLSTGMDIPDPWVR
DQTGIPQPAPGEAIFRVRQSGNEPAQTDKEMPPEKQEKTEQTALSARLPEAKSSPRDELDDMGDAVPARRLQDAIDPLLE
PVIDAIRTRGLADALADLPALYREMDDSRLMTLLSDAMFAAEMKGMLDGTGD
>SEQF1516_EDU86420.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWVSIVKDYVVPILSATATAGGIFMALMRKTFVPREAFEKLSDRVEKVETRLSSLPTEAEVNRLNVEIVTLRGELKTTNA
TLRSVSYQNELLLEQAVRKKTQ
>SEQF1516_EDU86421.1 integral membrane sensor signal transduction histidine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRNLRHWVILLFIVLAWGTGWLMLWTLSFYLTNNGQQAVLFLPQGVYLALVILLSRRYWPALVLPPLLMMFWLHSEQLL
NGYLMLATPVISLFPALLAQNFWHRFPLYWQRLTLLLATVTAASLLNTALLSPFMSGPIMLPGLTSFTGGVLLTPFVYLI
FEFLRQQHRYQLLGLDTHNPPLRTSLIIWCSLFFIIGIGTQMVLSPEIERLLLIVVFLPNVVMAWKFGWQGGVLSGLLGS
MMITIARQIGVGFSNLVELEIFLATQALLGIGLGIAISRQQHLALNLHHYRQRLEAELAARRALAEKLIHTEEDTRKNLA
RELHDEIGQNITAIQIQSQLVKRARDPAQIQSAASQINELARRIHLSTRQLLRQLRPPALDELTFREALLHLINEFAFSE
RGIHCQFAYQLNSTPENETVRFTLYRLLQELLNNICKHAEASEVTIILRQQGEVLHLEVSDNGVGIASGKMAGFGIQGMR
ERVSALGGDLTLEKQHGTRVIVNLPTFLQQIAG
>SEQF1516_EDU86422.1 regulatory protein UhpC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHARSAREINQCYRTLRPRLLMCMIIGYAAFYLTRKSVNYVLPALQTDLGLDKGDIGLLGSLFYLSYGLSKFTAGLWHDS
HGQRGFMGVGLFATGLLNVVFAFGESLTLLLVVWTLNGFFQGWGWPPCARLLTHWYSRNERGFWWGCWNMSINIGGAIIP
LISAFAAHWWGWQAAMLTPGIISMALGIWLTLQLKGTPQEEGLPTVGHWRHDPLELRQEQQSPPMGLWQMLRTTMLQNPL
IWLLGVSYVLVYVIRIALNDWGNIWLTESHGVNLLSANATVMLFEVGGLLGALFAGWGSDLLFSGQRAPMILLFTLGLMV
SVAALWLAPVHHYALLAVCFFTVGFFVFGPQMLIGLAAVECGHKAAAGSITGFLGLFAYLGAALAGWPLSLVIERYGWPG
MFSLLSVAAVLMGLLLMPLLMAGITTTHARRIKQ
>SEQF1516_EDU86423.1 nuclease SbcCD, D subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAIIVAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVL
AGNHDSVATLNESRDIMAFLNTTVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
YQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYIALGHIHRAQIIGGMEHVRYCGS
PIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVTQPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDI
QRKIQALTESLPVEVLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFTTTLHTLAGEHEA
>SEQF1516_EDU86424.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEEMTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFH
LQVAEPTSYLCRYL
>SEQF1516_EDU86425.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNYATETDMRARYREDLLRPLLAVPRSDEPDTRKLNRALTDASALIDSYLSARYTLPLEVIPAVLVQHCCAIAFYYLCDQ
RASDQARDRYREALAWLKDVMNGNVPVGVDTNGAAPESGDLPQVQSDAAVFGRNQKGFI
>SEQF1516_EDU86426.1 putative regulatory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQGKEPVIERIGMLTKRYPSRSAAARAWGININTLNSYFKGGQTQPAPRESILIRISESEGVSLEWLKEGKGESPNDVG
ICGNFGCSGDKGDQLTQMLSFLTKDEREQLTNLLARKGVETVLTLLDKENQDLLQLEGRKRLAALMIVDMPDDCVREILE
KTETSRQSNPVESKAG
>SEQF1516_EDU86427.1 pyrroline-5-carboxylate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAALHDKFGINAAESAQEVAQIADIIFAAVKPGIMIKVL
SEITSSLNKDSLVVSIAAGVTLDQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLETGEHPGALKDMVCSPGGTTIEAV
RVLEEKGFRAAVIEAMTKCMEKSEKLSKS
>SEQF1516_EDU86428.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYFYFKLDRVQTNKYFTKYQQTVLPLRNSILRALLKNTGAAGLRLKPFAMDVISEFYFSGALPAGWRKRDDVAFIGDGP
CFIARPDESCPEGPAIAAMIETAERELRKRPDFLVWLCEKLGVMRIPSMFNTDSWWTPSLSRDALCVVFKVGAYGREIKG
CIPEECQEIKHSEYVALTEE
>SEQF1516_EDU86429.1 putative addiction module antidote protein, CC2985 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKITSVSVGEQLDSFITRMVQSGRYGSASEVMRSALRLLEQQESRDEAVRNAVIEGLESGESSMTLRDIAAERKQKHRV
>SEQF1516_EDU86430.1 nucleoside-specific channel-forming protein Tsx [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYADAPV
FFGGNSDAKGIWNHGSPLFMEIEPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
LSMNVYAKYQWQNYGAANENEWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLGDDSGNAINGIKTRTNNSIASSH
ILALNYDHWHYSVVARYWHDGGQWNDDAELNFGNGNFNVRSTGWGGYLVVGYNF
>SEQF1516_EDU86431.1 YjhS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPGNFTVKVSGGTAAFLEAPFPPAETKGGMTFADCLISFNTRDCLWVRPVSGDPSVEITGAGIGAVIPLSADVAGTAEPS
DWDNAETHTRPSGNETASSSPSWYYVVVLAGQSNGMAYGEGLPLPETYDRPEPRIMQLARRSTVTPGGKACQYNDIILAD
HCLHDVQDMSGKNHPKADVAKGQYGTVGQGLHIAKKLLPFIPADAGILLVPCCRGGSAFTAGADGTYSDSTGASEDSARW
GVDKPLYKDLISRTKAALAKNPKNRLLAVVWMQGEFDIDAKPTEHSALFLAMVEKFRADLAEQAEQCTGGSAAGVPWICG
DTTYFWKQKNEPAYQAIYGGYKNKTDKNIHFVPLMTDENDANVPTNNPAEDPDIESIGYYGSTWRNSAATWTSADRASHF
SSWARRGIISDRLATAVLTHAGRTTVKADVPSSETEAPVPSPSETEAVTTTLLSYRVSESEGNLKAQGWEPAGGKAEIIS
DAGGTGGKAMKLTKETGKSSWYLDHDAGTGAELLKNGGLISCRFKVPGDLVANQYVMGLYWPVSSLPQGVTLTGDAGNNL
LASFYIQTDAKDLNVMYHNAKVATNNQKLGTFGAFDNEWHTLAFRFAGNNSLQVIPVIDGQDGAAFTLTQSPVGTFPVDK
LRVTDITKNATYPVLIDSIVVEVKKAVTE
>SEQF1516_EDU86432.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVGLVTWVISFWLAGLIIRRRDEETENAQ
>SEQF1516_EDU86433.1 hypothetical protein ECH7EC4501_4057 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINFMAAMVRWQALSDLYREKYSSPHLRLHPGAEVYH
>SEQF1516_EDU86434.1 penicillin-binding protein AmpH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRSLLFSAVLCAASLTSVHAAQPITEPEFASDIVDRYADHIFYGSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLD
SVVRIASLTKLMTSEMLVKLLDQGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMKDTTYTPSPDQCRRLMVAERGAS
PCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQRSNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEG
RPGIIQKTGGGGGFITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS
>SEQF1516_EDU86435.1 major head subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTPITPAMITALMTGYRSDFQAGMSMAPSQYKKIAMTVPSTSKSNTYGWLGQFPQFREWIGSRVIEKMKAYGYAIVNKT
FEGTVAISRDDFEDDNLGIYSPLFQEMGRAAAVQPDELVFAALRDGISAACYDGQNFFDTEHPVYPKVDGSGDAQMVSNM
FVAKTGSVGAQADYSGPAWYLLDCSRAVKPLIYQDRRKAELVAQTKVDEGRAFTDNEFVFGASARRNVGYGFWQMAYMMQ
SPLTLDALWHGWSAMREFTADGGRKLGIKPTHIVVPTSLEKQAVQLLERELFADGNATVSNEMKGKLELVVADYL
>SEQF1516_EDU86436.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEENKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMN
RITIANGDIGFNFTDGNLIKKIFVDKLTQAQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
EQDEDNPYADFKVPDDLMW
>SEQF1516_EDU86437.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTRKKKTAVSEAAVMEAIREALEGADPRTAGLTEQLAKGYVDLLDGLPFGETREYRVTFRELTAKDSIDAEAEAERVVE
TNNGPMLIASPSLRGVALLRRQIAAVGDIEGPLSPRQIGQLSERDLSRLMAAVSLLDTALAGKLAADRGRSGAVSGSD
>SEQF1516_EDU86438.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPIPGDDTAVYLNNFSGKYSQPGAAKNSFSIYRVNAVSMTAPEAQFKRL
>SEQF1516_EDU86439.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRRLVFFAIIVPVWGVGFIFAVTGNLSMMPDIWFFIRMSLFLFIMNLLIDIYIRITGKHK
>SEQF1516_EDU86440.1 2,3-dihydroxyphenylpropionate 1,2-dioxygenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPELVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSA
AGELPVPVELAEACAHAVMKSGIDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGR
FTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVISAAEKFVEDQRTLHPLNPIWDNQ
FMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWVAAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN
>SEQF1516_EDU86441.1 puative autotransporter/pertactin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHSWKKKLIVSQLALACTLAITSQANAATNDISGQTYNTFHHYNDATYADDVYYDGYVGWNNYAADSYYNGDIYPVINNA
TVNGVISTYYLDDGISTNTNANSLTIKNSTIHGMITSECMTTDCADDRATGYVYDRLTLSVDNSTIDDNYEHYTYNGTYN
NAADTHVVDVYDMGTAITLDQEVDLSITNNSHVAGITLTQGYEWEDIDDNTVSTGVNSSEVFNNTITVKDSTVTSGSWTD
EGTTGWFGHTGNASNYSNTLTADDVAIAAIANPYADNAMQTTVTLDNSTLMGDVVFSSNFDENFFPQGANSYRDADGDVD
TNGWDGTDRMDVTLNNGSKWVGAAMSVHMVDEDGDGSYDGYAVGTEATATLLDIAANSLWPSSTVGVDNINTQYDENGHI
VGNEVYQSGLFNVTLNGGSEWDTTKSSLIDTLSINSGSQVNVADSRLISDTVSLTGGSNLNIGEDGHVATNTLTIDNSTV
KMSDDVSAGWGLEDAALYANTITVTNDGLLDINVDQFDANPFQADTLNLTSTTDTNGNIHAGVFDIHSSDYVMDTDLVND
RTNDTTKSNYGYGLIAMNSDGHLTINGNGDNDNTASIEAGQNEVDNNGDHVAAATGNYKVRIDNATGAGSIADYNGNELI
YVNDKNSNATFSAANKADLGAYTYQAEQRGNTVVLQQMELTDYANMALSIPSANTNIWNLEQDTVGTRLTNSRHGLADNG
GAWVSYFGGNFNGDNGTINYDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMNDRSGQVDQDSQTAYIYSSAHFANN
VFVDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFGLKAGYDFKLGDAGYVTPYGSISGLFQSGDDYQLSNDMKVDGQ
SYDSMRYELGVDAGYTFTYSEDQALTPYFKLAYVYDDSNNDNDVNGDSIDNGTEGSAVRVGLGTQFSFTKNFSAYTDANY
LGGGDVDQDWSANVGVKYTW
>SEQF1516_EDU86442.1 protoheme IX farnesyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEPQLQHDDALRAAVMMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLVGVSLVVASGCVFNNYIDRDID
RKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLWFGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAA
PPVIGYCAVTGEFDSGAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAVATLMLSL
GGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALSVMMSVDFMVPDSHTLLAAVW
>SEQF1516_EDU86443.1 2-dehydropantoate 2-reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVETDGSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAV
KSLASTLPVTTPILLIHNGMGTIEELQNIQQPLLMGTTTHAACRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
PDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIEREGHHTSAEDLRDYVMQVIDATAE
NISSMLQDIRTLRHTEIDYINGFLLRRARAHGIAVPENTRLFEMVKRKESEYERIGTGLPRPW
>SEQF1516_EDU86444.1 shikimate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMTVAEIVEREEWAGFRARETAALEAVTAPSTVIATGGG
IILTEFNRHFMQNNGIVVYLCAPVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
ISEIRSALAQTINC
>SEQF1516_EDU86445.1 alkaline phosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGARRLTADQTAALRDSLSDKPAKNIILLIGDGMGDSEI
TAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAG
EWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPT
LAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKDGNTLVIVTADHAHASQIVA
PDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
>SEQF1516_EDU86446.1 [acyl-carrier-protein] phosphodiesterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHMHRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVM
WDHFLSRHWSQLSPDFPLQEFVCYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALR
DSWYDLDAHYAALETRFWQFYPRMMAQASRKAL
>SEQF1516_EDU86447.1 e13 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFFKTSNPSALAAWQKYQQDCQKVKDEAKRLEAVLNVACRSVFVSGISGFCFKGLRFMDDKYPFHRDLWRKPTASNGWSC
TPRTSRIPKALRVASDELNSLWREYSPVTYARTDALLFWLGIDFSAILHGPVKWFCVDDVIYLQCEDDSAKRKMTEILSD
EFYAAEKRVGG
>SEQF1516_EDU86448.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNASAARRVLRDEIAMIVCSPVLLWEQYFVAGQFDKGIKRSC
>SEQF1516_EDU86449.1 putative endolysin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKLPAPLRKKLIALVLAGAGTFTIATHYTGYWEGKENSTYIDPTGTPTICYGHTGPDVKPGMTLTDEECLELLEKDMKW
AFAAIDRRVQVPLTRGQTVALASWIFWAGETNFRNSTLLRLINAGQMPASCKQYIRWIYSKGVKLPGLEARRSADEWLCR
YDLPKV
>SEQF1516_EDU86450.1 protein SbmA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKSFFPKPGTFFLSAFVWALIAVIFWQAGGGDWVARITGASGQIPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSP
HRWQYWSILGTALIIFVTWFLVEVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIAFLPVLVTLSAHVPELPIIGHIP
YGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVEAAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFN
IARILYLQVDNVFGLFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHELDGDKIQE
VTHTLS
>SEQF1516_EDU86451.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNINVFRLILLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLNQETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQI
GTLRMSLVNITPDTDGTTLTLRIQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
ISVDQLGFVRIHDIQPVMQ
>SEQF1516_EDU86452.1 plasmid stabilization system protein, RelE/ParE family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYKLSGKAVEDFRGIYDYTLGKFGDEQADRYTDSLGTFLDTLSQMPEIGQDYDAIPEVKKIAFRFHTVYYVIRVDDILIA
RILHQLMEPRRHW
>SEQF1516_EDU86453.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDAFTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKP
GDHVIPLYTAECGECEFCRSGKTNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAIDTNPKKFDLARRFGATDCINPND
YDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALESAHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGR
SQLPGMVEDAMKGDIDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY
>SEQF1516_EDU86454.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPYQPLPLAQLITQTQQDISQRLPGSQPGVNETTLNAIAYALAGLSAQEHEHLAWISRQIIPTEADEAELLKHCAFWGVI
RKPASRADGPVQLMLTTDAGITEGVLLQRSDGVVYRITGSATGKAGTLNVNVEAESAGRAGNTPTGTRLSFITPQAGINQ
TATVTGTGLTGGADVETVPELLSRLVFRVQNPPSGGTQYDFERWAREVPGVTRAWCKPEWPEAGSVGVTFVQDNNPDIFP
GEGDVKRVADYIRSHDDPATGQPVGQPLGPTISVFKLTNKPVAFEIRIVPKTPENQAAVKQALTDLLYNESRPGGLVLPS
SFWRAVAGVKGLEDFEVRSPLKSVMAGDTELLTVGEITWL
>SEQF1516_EDU86455.1 riboflavin biosynthesis protein RibD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQRAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGR
TPPCCDALIAAGVARVVAAMQDPNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWSELDVQTQALYPQHHLRQPVRIVIDSQNRVTP
EHHIVQQPGETWFARTQEDSREWPETVRTLLIPEHKGHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVY
IAPKLLGSDARGLCTLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA
>SEQF1516_EDU86456.1 Fe(3+) ions import ATP-binding protein FbpC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQIGIKKIAALYTHRSIQQRDICMVFQSYALFPHMSLGENVGYGLKMLGVSRSEVKQRVKEALAMVDLEGFEDRYVDQIS
GGQQQRVALARALILKPKVLLFDEPLSNLDANLRRSMRDKIRELQKQFNITSLYVTHDQSEAFAVSDTVLVMNKGHIMQI
GSPQDLYRQPASRFMASFMGDANLFPANFSEEYVDIYGYRLPRAAHFPVQGSGTVGIRPEAITLSNHGEESQRCVIRHVA
YMGPQYEVTVEWHGQEILLQVNATRLQPDIGEHYYLEIHPYGMFVLADAA
>SEQF1516_EDU86457.1 beta-lactamase fold protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKITQIRNATQIIQYAGKTFLIDPLLAPKGSYPGFAGTARAEIRNPTVELPCDLTTLLNVDALIVTHLHEDHWDETASRV
VPKDKLIYVQNEQDAESLNKQGFTHLTVLTDETKFGDITLHKTTGQHGSDRTYADPAMAKRLGAACGVVFQHPTEKTLYL
AGDTLWRDDVEATMLTFQPEVVVLNAGFAHVLGHGAIIMGAEDILKTHFTLPEAQIIATHMEAVNHCLLTRDALKEYARD
NQIIEFVNVPEDGETLTF
>SEQF1516_EDU86458.1 DNA circulation protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASGDGRGAFRGVPFLVWREQRERGGRNIVRREYPLRETGGADDLGPKLAEFTFSVLVMGDDVQTQRNRLRDALRAPGAG
ELLHPDYGTLNVLINSFESRYNAAEQGVVEFTINVTPVSDDTAPAVTQDTAAILEQKSTTALGKVFETLEAGWTVISDGM
HDVQAMTETISDKVSALENAVSGMGIVQDISAFTATFTALKGNATALLTAPSRMASSFAGLFSALITLPSLPSLSSGGLN
TRPGGSIGRTTSAFSQGMPQLYRTLSSLRYVLDEQDNPQTLIGLTPAAQKNIRLIRAVMQSAAVVAQAQTVGKLLDQVLS
QETLPDSDAAHRTWPVWLESSVDLQRINRDLSEALERQVMTLSGQGYTATALTLRDARLALTEDLNTRGVQLPGATVVTV
RTTEPALVTLYRATGNSTGWQRFVRRNGIVDPLFIPGGHSVEVISEQQG
>SEQF1516_EDU86459.1 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGSGPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSD
SIVNSGSRSDLNARILKSVVDQLDIAKIHLLGNSMGGHSSVAFTLNWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQ
LYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFPDFGPRLAEIKAQTLIVWGRNDR
FVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADAFNQLVLNFLARA
>SEQF1516_EDU86460.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKVRVIFEFKHVSHDEKPAGNDCVEVHEKIGVDVKTERDTNNRPTSLCDVYASILQYHSPEIIQFLSAEFQASVQAFGA
DAIIKRHRVHKASGTLQ
>SEQF1516_EDU86461.1 phosphate regulon transcriptional regulatory protein PhoB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVV
MLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTVRGTGYRFSTRF
>SEQF1516_EDU86462.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPIPAEWLADCLVPPAPEPFTFGASVTYNLQLLAVIKNCNVDKASIRRLETRRQHEFTDMAGTPAVPAGKTK
>SEQF1516_EDU86463.1 thiamine biosynthesis/tRNA modification protein ThiI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVVRHWDNIEVRAKDENQRLTIRDALTRIPGIHHILEVE
DVPFTDMHDIFEKALVQYRDQLDGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLL
LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEIGVRQVAHYLWNRFGSSHRVRFV
AINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVAERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYD
KEHIINLARQIGTEDFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTGQEVVEVET
VNDFGPNDVILDIRSVDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNRTWLLWCERGVMSRLQALYLREQGFKNVKVY
RP
>SEQF1516_EDU86464.1 tail fiber [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFHVDNNSGVANMPALAPAQSNTTTWFTEGDGQKGISWIGQDWLNILQAELLNILAEASIQPDKAQLNQLTLSIKAIIAA
NAFSRKNNLKEIADAGAEAQRLARGYLGLGALATKNSLGPGDVNALAKDQNLADLENAGTARNNLDVYSKSEGDNRYLRR
EQNGADIPDKGAFIDNVGLRETVNKAADALPSGGTAVAANRLATPRNINGVPFDGTLDINITSGMTQSTADGRYVQNVQL
GAQSYHSPGGNEMSWNYSAPSGCMLSGINVQETGSRSADNIGGVYYRPVQIYINNAWRTVSSV
>SEQF1516_EDU86465.1 phage virion morphogenesis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSIDAAVVVDVARLQRVFARLQFVGGGKDLARSVASSLLSSSEMAFEQEKEPDGERWHDWSDPYRKWRTRKGNMPGKIL
TLNGDLARRLTTDYGDTWALIGSNEPYAAIHQWGGLPGMPPGPAAIGARPYMGFDQVAEQEIMDEIRKRFKKATETP
>SEQF1516_EDU86466.1 hypothetical protein ECH7EC4501_4005 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFCVGNYLNKRNVSLVIKQKIFAQSISFAIKIIPPDTMKL
>SEQF1516_EDU86467.1 oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPIIKRALEGGINFFDTANSYSDGSSEEIVGRALRDFSRR
EDVVVATKVFHRVGDLPEGLSRAQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGRLTRPWGETTARLVSDEVGKNLY
KESDENDAQIAERLTGVSEELGATRAQVALAWLLSKPGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPV
VGFK
>SEQF1516_EDU86468.1 taurine dioxygenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSERLSITPLGPYIGAQISGADLTRPLSDNQFEQLYHAVLRHQVVFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVD
EIIVLDTHNDNPPDNDNWHTDVTFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
EYKYRKTEEEHQRWREAVAKNPPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKESEALLGFLFAHITKPEFQVRWRW
QPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGDKPFYRAG
>SEQF1516_EDU86469.1 taurine ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQISHLYADYGGKPVLEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSIQLAGKRIEGPGAERGVVFQNEG
LLPWRNVQDNVAFGLQLAGIEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD
AFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSPGPGRVLERLPLNFARRFVAGESSRSIKSDPQFIAMR
EYVLSRVFEQREAFS
>SEQF1516_EDU86470.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPEIKGTVTEELVKQALYSEEVNRVLKAQVRKDFEAQIDAYVDEVLARMVGRSPAENSTENDPQPVEQPEPVQPGTDGTM
M
>SEQF1516_EDU86471.1 D-alanine--D-alanine ligase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGIDKQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVP
GKHEHQLIDAQNGQPLPTVDVIFPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKVIVEQGIKGREIECAVLGNDNPQ
ASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAPEINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLP
GFTNISMYPKLWQASGLGYTDLITRLIELALERHAADNALKTTM
>SEQF1516_EDU86472.1 2-keto-4-pentenoate hydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHINVQYDVAQGRRVVGRKVGLTHPKVQQQLGVDQPDFG
TLFADMCYGDNEIIPFSRVLQPRIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNAS
CGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASLGEPLRAGDIILTGALGPMVAVN
AGDRFEAHIEGIGSVAAAFSSAAPKGSLS
>SEQF1516_EDU86473.1 bacteriophage Mu Gp45 protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMNDEVISRLLAPVMRGVRLLFGRGVLTGTTDTLKIQNVQITGMDGETFDDVERPQQYGQISVPLPGAEVFLACAGGQRD
QAVVLVVEDRRSRPTGLTAGDTGVYHHEGHRIRLTKNGRIIVTCKTLEIYADEGVQVDTPEAHFTGNVTVDKNLHVKGNV
SIDGTGRSQGTFTMSEAVIAGITYSGHVHHDNGEGSKTGGPENG
>SEQF1516_EDU86474.1 DNA transposition protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDINDVIKTIDELIDGGVLTQYAIAREAGISDGTLSAFRKGKYKGDNAAVAASLRSWYENWNKQSALPEPPQFVETQTV
QELRALFQAVRLMGCINVIVGVPGVGKTATARNYCQEQPNTWMITLSPAHSSVTECLLELADALGIDYTRANKGALSRAI
RRRLMGTRGLVIVDEADHLGIDGLEQLRAIQDATGIGMVLIGNPRGLFKGGRRAFDDLSRLFSRLARTKQLRKAKKADVL
AIARAWGISGEAELAVMQAIAEKPGALRVLTHTLNQAWLTASGEGAALTEKHINAAFKEVYTNPELLSQV
>SEQF1516_EDU86475.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTIFIKPAPGRLIRDPDTMRPLAQEGEEKPFTPFWCRRLDDGDVIQAEKAAEEAPAVSADATTATEKPVAQPASDKEKP
Q
>SEQF1516_EDU86476.1 protein araJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALLVVILQAITLLATVIGSRSGSCDGGMKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMISYYALGVV
VGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIKPGKVTAAVAGM
VSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDIRDEAKGKLREQFHFLRSPAPWLIFAATMFGN
AGVFAWFSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCGGMKTTS
LIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFNLGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSL
LLYGRYKRQQAADSPVLAKPLG
>SEQF1516_EDU86477.1 nuclease SbcCD, C subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKTTLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECL
AEVEFEVKGEAYRAFWSQNRARNQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQVQSLTASLQVLTDEEKQLLTAQQ
QEQQSLNWLTRLDELQQEASRRQQALQQALAEEEKAQPQLAALSLAQPARNLRPHWERIAEHSAALAHTRQQIEEVNTRL
QNTMALRASIRHHAAKQSAELQQQQQSLNTWLQEHDRFRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLNALA
AITLMLTADEVATALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLMVTIQNVTLEQTQRNAALNEMRQRYKEKTQQLADV
KTICEQEARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGAALRGQLDALTKQL
QRDENEAQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQDEHERQLRLLSQRHELQGQIAAHNQQIIQYQQQIE
QRQQQLLTALAGYALTLPQEDEEESWLATRQQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDDLPHSEETVALDNWR
QVHEQCLALHSQQQTLQQQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQTLV
TQTAETLAQHQQHRPDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDADNRQQQQTLLQQIAQMTQQVEDWG
YLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQLTRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSL
ALALALSDLVSHKTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVKKINGLGYSKL
ESTFAVK
>SEQF1516_EDU86478.1 4-hydroxy-2-oxovalerate aldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSIEVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHA
KIATLLLPGIGTIHDLKNAWQAGARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGA
TCIYVVDSGGAMNMSDIRDRFRALKAVLKPETQTGMHAHHNLSLGVANSIAAVEEGCDRIDASLAGMGAGAGNAPLEVFI
AAVDKLGWQHGADLYALMDAADDLVRPLQDRPVRVDRETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVG
GQEDMIVDVALDLRNNK
>SEQF1516_EDU86479.1 protein-export membrane protein SecD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVAASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDS
TDTQLRAREALMGVMGDKYVVALNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
KGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDARLSEAREYAVQQNINILRNRVNQ
LGVAEPVVQRQGADRIVVELPGIQDTARAKEILGATATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVI
LTGDHITDSTSSQDEYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEVINIANIQS
RLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNIEQGLEACLAGLLVSILFMIIFYKKFGLIAT
SALIANLILIVGIMSLLPGATLSMPGIAGIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITT
LIKVIILYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI
>SEQF1516_EDU86480.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRGKLISAIHVAKRELALDDETYTSALLAATGKTSCRDMSPDELSRVLDVFKKRGFKVRQNPVNRALKPGTVTAKIRAIW
KVMHRQGFITDGAETALNRWVKSQTAAQNGGEGVANWQWLEQHPALASDVLERLKRWHRRKMLAAMGMPERTLMGYDAVC
RQYEKSLPR
>SEQF1516_EDU86481.1 branched-chain amino acid transport system II carrier protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTAAFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKV
AGVLLATVCYLAVGPLFATPRTATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
ILSVAAIVWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGVTEARLLTRYTVWAGLMAGVGLT
LLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFGGGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFI
LGGFSMVVSNLGLSQLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAFSDILPSWA
QRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH
>SEQF1516_EDU86482.1 hypothetical protein ECH7EC4501_3990 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPERAHLIWLVNRRDTFAKTAKCANSLTIADFFLKTLCS
>SEQF1516_EDU86483.1 manno(fructo)kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIATLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANS
TWLNGQPFDKDLSARLQREVRLANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
PWMDEDELRYREEVPCYCGKQGCIETFISGTGFATDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVV
NILDPDVIVLGGGMSNVDRLYQTVPQLIKQFVFGGECETPVRKAKHGDSSGVRGAAWLWPQE
>SEQF1516_EDU86484.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFVHTMLLYFCAVVSALYLVSGGYKVIRNYIRRKIDDAAAEKLSKTAQAPSSPNDPTPL
>SEQF1516_EDU86485.1 phosphatidylglycerophosphatase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLAAIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMG
VHDHGSIVWDEFIGMWITLMALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILYFIG
HHWPLGIL
>SEQF1516_EDU86486.1 phage Mu protein F like protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQGIDLGYAATLPSKEAVAYFRAKGAHISWNWFETDADVHARSFTAAKAARLDVLTTLQAEVQRAIDEGISQKAFIRTL
TPRLQKLGWWGKQIVVDSAGNAEEVQLGSPRRLALIYNVNTRVAYNAGRYTQMMNNTDTHPFWQYVAVMDSRTRPSHSTL
NGLVFRYDDPFWKTHYPPNGWNCRCRVRPLSQARLDAMGLSVSSGEDHLSTRNVEAGVDKQTGEVREMPVTTYSDGTRTM
TPDVGWSYNPGSAAFGTDQALIRKLIEVKSPALREMVVQEMNNSPERQLAFRIWAKNIMKTRRGGHDIRTLGFMTESIAQ
AVESRTGTPPARLLAMSGKNVLHADSVKHQNDGIALTPEDFAQLPAMLAAPDAVLWDHVHQNLLYITETRDGTAKIAVNA
PYGVKRQPDKLDVVINAYRVNKFDIEKAIEGGKLELLEGKL
>SEQF1516_EDU86487.1 hypothetical protein ECH7EC4501_4016 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTADERNVVKAATDDSMEAAYMLKDNIRWYYHNGDLSLPANFSNKNKLVVNGNLTISGDYDDYLSGNGHLIVLGNVIVDN
FINHDFAYVKGQMTAKGLVYADYNDHNFEVMKGISARGIIVSDKATQFEVIKAEFYINEDGSGEGYNWDENIQKAYSLVT
ADLYDHTEIETDNISNAYPDYDSVADNIVQGLPLFRDKAAPEINEKLKWIETGKLDNFPANKIKHQDPLVARFLTHTESL
SPAVMLQLLQHPDDQTRESMAQSWPAQQMHWLTDELIKDEAVARGLVKNSNISADVNKKLMSVPVESVQLEQARQDNLSP
DIVASLSHSPFLSVRKTLLSHYDYAWLVPTAVADELINNEDPELRERITGADLTAQQAVMLSKDKSLKVREALARTLTEL
KITQLSATLRTEDIERIAEQMYLDNKENKNIVKVLLIALPEMRQLSLAKEDVHNLREGARYLTSKDVISYLLTQHDVPTV
WDELARDKLLPLEYKKQLWQRTLNLMMSKRQEDQEQAYEVQLALIDNGVVDEEMLNNAIDLLVDLPAEYRYRMRNQLFDN
KELPSGIINKLDQQYRFNSDWALAVVSMKNSTRRQSERGLHRWNHEDSDIFAELATIKDKSDDEWWRALLQSRNDHLRQT
ALRNAHTPASLLTTLTESQDRSLAINNPQLAADVKTVWLKEDPSLLLFVDKPDLSQLRDLVKTGATRKIRNEARHRLEEK
Q
>SEQF1516_EDU86488.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDASKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLD
VPENIVHSGKTWFVEAKLKQGIESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
FRD
>SEQF1516_EDU86489.1 delta-aminolevulinic acid dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFG
ISHHTDETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQG
ADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEK
KILR
>SEQF1516_EDU86490.1 hypothetical protein ECH7EC4501_4024 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKDAHNGSLAKKHGRDYTQTDVPFAFFCATEINNLKICATSFS
>SEQF1516_EDU86491.1 protein gp48 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVTLTPHQRALLQLLPDGLAWDKRPSSVLAALCLGLSHSTERVSWTGNQMLAERFPDSSRLLLEDWERYLGLPECDMTG
ATIQERQRYAGNKYRMKPSLNREFYIRFAAEFGYEIDIQPSPDSQWVSIVTINSETGYRNMNVLDDILTPLRIYEGGALE
CILNRYKPAWQTFIYVYANSHEEENI
>SEQF1516_EDU86492.1 taurine ABC transporter, periplasmic taurine-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNTFAKESGATVDWRKFDSGASIVRALASGDVQIGNLGS
SPLAVAASQQVPIEVFLLASKLGNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHPEVVKAFSKSAIDAQQPYIANPD
VWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQQQTAELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ
>SEQF1516_EDU86493.1 hypothetical protein ECH7EC4501_4031 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGLNLLNICPDRYERFLVLFAHDVMYNMLQDNPVVEQRYDNFKFEFIETVYYWY
>SEQF1516_EDU86494.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDFITEDQRLVILRSLADYNGELGESVLQDCLDDYGHRVSRDTVHTHIAWLAEQGLVRKRVLINGYFIAELTGRGQDVA
EGRVCVPGVKKPRARG
>SEQF1516_EDU86495.1 DNA-invertase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIGYIRVSTNDQNTGLQRNALECAGCEQIFEDKMSGKTTQRPGLKRALKKLKPGDTLMVWKLDRLGRSMRHLVALTDEL
QQQGINFRSLTDNIDTSTPMGRFFFHIMGALAEMERELIVERTRAGLAAARERGRTGGRPRRLTQEQYEQVGRLLAGGVS
RRQVALIFDIGLSTLYRYYPASVSEK
>SEQF1516_EDU86496.1 transcriptional regulatory protein UhpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRVVLVDDHVVVRSGFAQLLSLEDDLEVIGQYSSAAQAWSALIRDDVNVAVIDIAMPDENGLSLLKRLRAQKPQFRAII
LSIYDAPTFVQSALDAGASGYLTKRCGPEELVQAVRSVGLGGHYLCADAIRALRGGGQPAQALEILTPREREVFELLVKG
DSVKEIAFKLELSHKTVHVHRANVLGKLNCHSTIELVHFALDHHLLAGH
>SEQF1516_EDU86497.1 transcription termination/antitermination factor NusB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVDVLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQV
EKAVLRIALYELSKRSDVPYKVAINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK
>SEQF1516_EDU86498.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEHHTVAATDDSGLQVSGDNSVTVLAEVRCSRSAFRRAGFLFTRGRQQVEVTPEQLARLEEEPCLTVRILQTSADDAGS
VAGVVHAVAGTDLAEAEAEAEAEAEAEAEAEAEAEAEAEAEAGQDAPRKKTGNKAEQARA
>SEQF1516_EDU86499.1 queuine tRNA-ribosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPEEVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFM
QWKGPILTDSGGFQVFSLGDIRKITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVGEPKADMHRILEHVCPQIPADKP
RYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGHLFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDR
CNEILGARLNTIHNLRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD
>SEQF1516_EDU86500.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIDAKVLEGVKNWLSIYGRLTCGILAEKMNMPPSSMVYFLRDAVDAGVLTECNGFYDIPRPRPVQPVRRKCSQEGAADDV
QWCSFRKSLPWIEGHDIPSMAWEFAQGVLTCETVYVVVEVDEQAMKEGVPQFVMAYIDIRLGVIICGLSGWNITEHVLRY
LIVDRTAAPAGISAEVA
>SEQF1516_EDU86501.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEHPTAQEAMDAKKRYEDPDKE
>SEQF1516_EDU86502.1 cytochrome o ubiquinol oxidase, subunit IV [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHSTDHSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPAVILGTILAMAVVQVLVHLVCFLHMNTKSDEGWNMTA
FVFTVLIIAILVVGSIWIMWNLNYNMMMH
>SEQF1516_EDU86503.1 bacteriophage Mu Gam like protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKRVTKLKAAAEAAPQTREEVSRDIRTLGDIQREALRLETAMNDEVAEITARYTPQIENLKKEIKVLFKGIQDWCKTNR
DELTNGGKTKTANLTTGTVSWRLGNPSCSVSRDVEGVIEMLRRMGLERFIRTKEEVNKEAVLAEPDAVKGIAGIKVNKGA
ESFYVEPFEQDAGLNK
>SEQF1516_EDU86504.1 bacteriophage Mu tail sheath protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINFDGIGNDRRIPLIEVEFNNSMAVTGTPAQRQCVLLFGQARMKENAVDGAGVLDVPVRITRASQATELWGRGSMIALM
VAEFIAINPDAELYAIAQGNGTGQATAAAMNLTGTVTRDGIVYACVGGRRYTLPAPKGKKGKELTDELAALINADPDAPF
TASSGAGSGDNGAGLKGSLGITARFTGECSVHDVRLNYHDGEATPEGIQVAIAYPKQKAANPDITRSVAGMGDRQYNYVV
MPYKDDANLKIISDELLKRWGPAKMSDGVLWLAHTGTFGEVQAFGAKRNDFLATCTSIPKAPEPDYLWAAAVCATCAPSL
GADPARPLQTLALPSRMAPAPADRLTREERNSLLWGGIATVSVAAGDVVQIERQVTMYRQNVYGESDPSYLDVETIYTLS
WLRYSLRTFITQRFPRHKLADDGTPVRAGQNIVTPEIMKLQLISLGEEWVELGLVENLDTFKKNLLVERNASDRNRLDVL
CTPDLVNQFRFLAAQIRFIL
>SEQF1516_EDU86505.1 protein-export membrane protein SecF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGF
EEPMLQNFGSSHDIMVRMPPAEGETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVS
LTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPS
ILP
>SEQF1516_EDU86506.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQGASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPL
IVGGLAVFAAGSVIAALSDSIWGIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
KLGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLNFGIMCLHILLMSTFVALPGQLA
DAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRKMKQVFVFCVGLIVVAEIVLRNAQTQFWQLVVGVQLFFVAFNLME
ALLPSLISKESPAGYKGTAMGVYSTSQFLGVAIGGSLGGWIDGMFDGQGVFLAGAMLAAVWLAVASTMKEPPYVSSLRIE
IPANIAANEALKVRLLETEGIKEVLIAEEEHSAYVKIDSKVTNRFDVEQAIRQA
>SEQF1516_EDU86507.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKITTLSELQEMNMSIELRSSYEYRKILIAGGMKPEDAEKIVSFMDKECDKRDMPEIIMDDMILDSAVALSPLWIVHSL
AEIAKGTDKQAAVAALQTLNEMRISPRPTLIHMILSSMEDKANE
>SEQF1516_EDU86508.1 taurine uptake ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVAALQLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHL
AASLTRIVLALLAAVLIGIPVGIAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
VVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ
>SEQF1516_EDU86509.1 MASE2 domain/diguanylate cyclase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLPRAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAW
QIASRAVDPLSREIYNLKTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLELTGITV
SFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGVYNRRHWETMLRNEFDNCRRHNRDATLL
IIDIDHFKSINDTWGHDVGDEAIVALTRQLQITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTP
QVNLRISVGVAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA
>SEQF1516_EDU86510.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKLQPMGRKGRAPAHVRAWTPEEDALLIALYPSTPVKDIAVRIKRSFWGVHNRIVLLRGTYPELLKCKRLRFKPDEDKF
IRKNARTMTGKQIGEYLGRDRDSVHNRARYIGVSMKKYGELLPFTRIPDDDVHLIRELRDAESPRRLTFREIGEKFELSE
GTVSFIYHRRRTAEDVVLRELTT
>SEQF1516_EDU86511.1 3-(3-hydroxy-phenyl)propionate hydroxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVVEKLDKLIDYPRAIGIDDEALRTMQSVGLVDNVLPHT
TPWHAMRFLTPKGRCFADIQPMTDEFGWPRRNAFIQPQVDAVMLEGVSRFPNVRCLFSRELEAFSQQDDEVTLHLKTAEG
LREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDPVRPYVSAALPHAVRRFEFMVMP
GETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYTHNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAW
KLALVIQGKARDALLDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMRFKPMPQYY
GGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCNPLWGMSDEQIQQWRALSTRFIQVVPEVQIH
TAQDNHDGVLRVGDTQGRLRSWFAQHNASLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVEKVA
>SEQF1516_EDU86512.1 putative tape measure protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARNLRASLIVDLLGNISAKSRQWSQELGAFSRSGQAGLGGLGNAARRAGQETDVLGSRMQRTLAGVRGSIRHVTSDFDR
LQGSITGTIGRISNLYGMLAGGAAVYGFNRGFIRPAAEMETYMIRLNSLYKGDRAKTDDVRRWAIQNAKETTWGLAGVMQ
EYTSSLGFGMSDREARNFVTMLQDQGAVGGWSLSDAQGASLQLKQMYARGSIQAADANILATYGINAYRVLADRLGVDQK
VVRKLGEKGLLGPDSIRLLFQTLAEQARGAQKDAMNSWSGLTAMMGDVWDQFARDVMDSGPFEKLKGNLRGFLSWVDSAK
SDGSYHSLAESTASAMNQGFEYARDAVTGFYQAIRKVRDTLQALRDAGYGDALDRIGQGAQTAAKYLLYMYLATRALKMA
RAVGTGIIRPGAALLGYGLSAAAFLTSPFRRSPPAGTPPGTYQGRGQRFINFLTGVNPAAVQPVLVTNWPTGGLSGTGAT
DTSSGGRQGRGRRKRGPGRGRPVTPPLPPSPVPPSPSSGGAGFWGRMMGRAGGLLSSVGSRMGLGRFSGFFRSAGGLAGR
LGGGALWAGAMAAPVLLDGSASATDKGEAVGSLAGSIAGGALGAAAGPVGIAIGSTVGSYLGNYLGGWLTEAWQKLRGSD
DESSGQAVQKASARVELVAPEGWQARSIDIDDTSGHGLDVNVWNGGNYGLW
>SEQF1516_EDU86513.1 proline-specific permease ProY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSVLLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYA
QENLGPLAGYITGWTYCFEILIVAIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVAT
IIIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEIIGITAGEAKDPEKSIPRAINSV
PMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQHMGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAP
KIFSKTSRRGIPWVTVLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVKALKFKVP
GGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHDRQLAENQ
>SEQF1516_EDU86514.1 tail tube protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGKQYQGTATIRVNGQEYETLEGATFSPSGFEREVVKGAKVYGYRQKPREATLDCKFPAGGEGSPAADEINNWTAVTIE
FVADTGEVHMMTKAWSSEPASLDGGGEISVKFASASSTRVQ
>SEQF1516_EDU86515.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNLLVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIP
FLVGCLIFAVVALWLHWRHRRQ
>SEQF1516_EDU86516.1 protein gp32 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTKNTPKLAYAILNAISLSADGDGDWCQIMPAGRVKARDGRPEKPAEGWLINHAAVERMVSRVVALNQPVKIDYNHQTL
IEGHPAPAAGFVMASPENFRFSEERGFEVRPKWNPPALEHLRNNEFPWFSPVIGYDESTGEPVELRMLAITGDPGLTGMN
PVAALSADDLYNALNPPLKDTSMNEQLRQLLTALGLTVADGDEFTPELGTAALSALTGIKTRADAHDNLKTQVASLSAEL
ETAKGTPAGGIIDLTKYVPVETYNALRTEYVALSAQHGSTTLEQVLDKAESEGRIFKSERGYLEQLGGQIGVAALSAQLD
ARQPVAALTSLQTDTVTVPDKKTATAALSAEDIAAAKLLGKTEAEFLKMKEEMQ
>SEQF1516_EDU86517.1 phosphate regulon sensor protein PhoR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLERLSWKRLVLELLLCCLPAFILGAFFGYLPWFLLASVTGLLIWHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLH
QMQLRNKKRRRELGNLIKRFRSGAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTPLTVLQGYLEMMDEQPLEGAVRE
KALHTMREQTQRMEGLVKQLLTLSKIEAAPTQLLNEKVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRS
VISNLVYNAVNHTPEGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHAVNH
HESRLNIESTVGKGTRFSFVIPERLIVKNSD
>SEQF1516_EDU86518.1 S-formylglutathione hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELIEKHASFGGWQNVYRHYSASLKCEMNVGVYLPPKAAGEKLPVLYWLSGLTCNEKNFITKSGVQRYAAEHNIIVVAPD
TSPRGSHVADADRYDLGQGAGFYLNATQAPWNEHYKMYDYIRNELPDLVMNHFPATAKKSISGHSMGGLGALVLALRNPD
EYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKEAWLDYHPVSLISQGQRVAEIMVDQGLSDDFYAEQLRTQNLEKICQEM
NIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNMR
>SEQF1516_EDU86519.1 periplasmic ferric iron-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKMTFTSTLIASAVALATLTGAAQAKGRLVVYCSATNEMCEAETKAFGEKYDVKTSFIRNGSGSTLAKVDAEKKNPQADV
WYGGTLDPQSQAGEMGLLQAYKSPNLEQIMEKFRDPAKVKGNLSSAVYVGILGFGVNTDRLKEKNLPVPKCWKDLTKPEY
KGEIQIADPQSSGTAYTALATFAQLWGEDQAFDYLKQLNANVSQYTKSGIAPARNAARGETAIGIGFLHDYSLEKEQGAP
LELISPCEGTGYEIGGVSILKGARNLDNAKLFVDWVLSKEAQELAWKKGKSYQILTNTTAETSPNSLKLDDLKLINYDMD
KYGSTDVRKALINKWVSEVKMGK
>SEQF1516_EDU86520.1 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFTDLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEV
LVERMLDDKRILAHIRASKAPKPGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDA
DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVDTIEDHIMHSEYAEVPQDVVDAV
LAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPFFDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHT
MNAYKAAVEEKYRFFSYGDAMFITYNPQAINERVGE
>SEQF1516_EDU86521.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIFGVVMLAESRDFAELVAMKASALMKDMSMRSGVIKGNEFNQQG
>SEQF1516_EDU86522.1 putative tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQYNIFEVPDGCVLTGLDVAGDGNATVTAYYRPVQFLIDGSWKTASSA
>SEQF1516_EDU86523.1 multiple antibiotic resistance protein MarR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFKVLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVC
KGWVERLPNPNDKRGVLVKLTTSGAAICEQCHQLVGQDLHQELTKNLTADEVATLEHLLKKVLP
>SEQF1516_EDU86524.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLVCSVIFIHHAFNANILDKDYAFSDGEILMVDNAVRTHFEPYERHFKEIGFNENTIKKYLQCTNIQTVTMPVPAKFLR
ASNVPTGLLNEMIAYLNSEERNHHNFSELLLFSCLSIFATCKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCL
YISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYAFRKHFGNSPKRVSKEYRCQRHT
GMNTGNTMNALAI
>SEQF1516_EDU86525.1 diguanylate cyclase (GGDEF) domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHVHPISTFRVFQEGHLLRNSIAIFALTTLFYFIGAELRLVHELSLFWPLNGVMAGVFARYVWLNRLHYYAISYVAMLVY
DAITTEWGLVSLAINFSNMMFIVTVALLVVRDKRLGKNKYEPVSALRLFNYCLIAALLCAIVGAIGSVSIDSLDFWPLLA
DWFSEQFSTGVLIVPCMLTLAIPGVLPRFKAEQMMPAIALIVSVIASVVIGGAGSLAFPLPALIWCAVRYTPQVTCLLTF
VTGAVEIVLVANSVIDISVGSPFSIPQMFSARLGIATMAICPIMVSFSVAAINSLMKQVALRADFDFLTQVYSRSGLYEA
LKSPSLKQTQHLTVMLLDIDYFKSINDNYGHECGDKVLSVFARHIQKIVGDKGLVARMGGEEFAVAVPSVNPVDGLLMAE
KIRKGVELQPFTWQQKTLYLTVSIGVGSGRASYRTLTDDFNKLMVEADTCLYRSKKDGRNRTSTMRYGEEVV
>SEQF1516_EDU86526.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVDLTPYILPGVSFLSDIPQETLSEIRNQTIRGEAQVRLGELMVSIRPMQVNGYFMGSLNQDGLSNDNIQIGLQYIEHI
ERTLNHGSLTSREVTVLREIEMLENMELLSNYQLEELLDKIEVCAFNVEHAQLQVPESLRTCPVTLCEPEDGVFMRNSMN
SNVCMLYDKMSLIYLVKTRAAHPLSRESIAVSMIVGRDNCAFDSDRGNFVLKN
>SEQF1516_EDU86527.1 DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENLARFLSTTLKQLRQQRGWSLSRLAEATGVSKAMLGQIERNESSPTVATLWKIATGLNVPFSTFISPPQSATPSVYDP
QQQAMVIISLFPYDPQLCFEHFSIQMAPGAISESTPHEKGVIEHVVVIDGQLDLCVDGEWQTLNCGEGVRFAADVTHIYR
NGGEQTVHFHSLIHYPRS
>SEQF1516_EDU86528.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRAVFDSIDNIIIIILLRPDMSIRFARKADCAAIAEIYNHAVLYTAAIWNDQTVDADNRIAWFEARTIAGYPVLVSEED
GVVTGYASFGDWRSFDGFRHTVEHSVYVHPDHQGKGLGRKLLSRLIDEARDCGKHVMVAGIESQNQASLHLHQSLGFVVT
AQMPQVGTKFGRWLDLTFMQLQLDERTEPDAIG
>SEQF1516_EDU86529.1 mannitol dehydrogenase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGNNLLSAKATLPVYDRNNLAPRIVHLGFGAFHRAHQGVYADILATEHFSDWGYYEVNLIGGEQQIADLHQQDNLYTVAE
MSADAWTARVVGVVKKALHVQIDGLETVLAAMCEPQIAIVSLTITEKGYFHSPATGQLMLDHPMVAADVQNPHQPKTATG
VIVEALARRKAAGLPAFTVMSCDNMPENGHVMRDVVTSYAQAVDVKLAQWIEDNVTFPSTMVDRIVPAVTEDTLAKIEQL
TGVRDPAGVACEPFRQWVIEDNFVAGRPEWEKAGAELVSDVLPYEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDEHY
RHAAYALMLQEQAPTLKVQGVDLQDYANRLIARYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLAHDSKFDLLALGVA
GWMRYVGGVDEQGNPIEISDPLLPVIQKAVQSSAEGKARVQSLLAIKAIFGGDLPDNSLFTAKVTEAYLSLLAHGAKATV
AKYSVK
>SEQF1516_EDU86530.1 gram-negative porin family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLKIVAVVVTGLLAANVAHAAEVYNKDGNKLDLYGKVTALRYFTDDKRDDGDKTYARLGFKGETQINDQMIGFGHWEYD
FKGYNDEANGSRDNKTRLAYAGLKISEFGSLDYGRNYGVGYDIGSWTDMLPEFGGDTWSQKDVFMTYRTTGVATYRNYDF
FGLIEGLNFAAQYQGKNERTDNSHLYGADYTRANGDGFGISSTYVYDGFGIGAVYTKSDRTNAQERAAANPLNASGKNAE
LWATGIKYDANNIYFAANYAETLNMTTYGDGYISNKAQSFEVVAQYQFDFGLRPSLAYLKSKGIDLGRYGDQDMIEYIDV
GATYFFNKNMSTYVDYKINLIDESDFTRAVDIRTDNIVATGITYQF
>SEQF1516_EDU86531.1 nitrite extrusion protein 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALQNEKNSRYLLRDWKPENPAFWKNKGKHIARRNLWISVSCLLLAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPS
VSGALLRVPYSFMVPIFGGRRWTVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAR
QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWVPLLAIATIAAWSGMNDIASSRA
SIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFAMLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTL
INFIFMAIFSALLFLTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRMKMKGGSDEQAQREAVTET
AAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLTWLVYGRRKFSQK
>SEQF1516_EDU86532.1 peptidase, M16B family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLDNGLRYMIYPHAHPKDQVNLWLQIHTGSLQEEDNERGVAHFVEH
MMFNGTKTWPGNKVIETFESMGLRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAERGVI
TEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLLQFYQRWYQPNNMTFIVVGDIDSKEALALIKD
NLSKLPANKAAENRVWPTKAENHLRFNIINDKENRVNGIALYYRLPMVQVNDEQSFIEQAEWSMLVQLFNQRLQERIQSG
ELKTISGGTARSVKIAPDYQSLFFRVNARDDNMQDAANALMEELATIDQHGFSAEELDDVKSTRLTWLKNAVDQQAERDL
RMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQDAFWEQMVNNEVAAKKALSPAAILALEKEY
ANKKLAAYIFPGRNLSLTVDADPQAEISSKETLAENLTSLTLSNGARVILAKSAGEEQKLQIIAVSNKGDLSFPAQQKSL
IALANKAVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARTNNPEPGFQLINQRITHSTINDNIWASLQNAQ
IQALKTLDQRPAEKFAQQMYETRYADDRTKLLQENQIAQFTAADALAADRQLFSSPADITFVIVGNVAEDKLVALITRYL
GSIKHSDSPLAAGKPLTRATDNASVTVKEQNEPVAQVSQWKRYDSRTPVNLATRMALDAFNVALAKDLRVNIREQASGAY
SVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLTKGISEQELNEYQQNVQRSLDIQQRSVQQLANTIVNS
LIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLSHPVNTYTGVLLPK
>SEQF1516_EDU86533.1 nitrate reductase molybdenum cofactor assembly chaperone 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQILKVIGLLMEYPDEMLWECKEDALALIRRDAPMLTDFTRNLLNAPLLDKQAEWCEVFDRGRTTSLLLFEHVHAESRDR
GQAMVDLLAEYEKVGLQLDCRELPDYLPLYLEYLSVLPDDQAKEGLLNVAPILALLGGRLKQREAPWYALFDALLQLAGS
TLSSDSVTKQVNSEERDDTRQALDAVWEEEQVKFIEDNATACDSSPLNQYQRRFSQDVAPQYVDISAGGGK
>SEQF1516_EDU86534.1 hypothetical protein ECH7EC4501_2667 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTSVCNLLENSTKSPQRQNAMQNQEGRFQNFFALICKTE
>SEQF1516_EDU86535.1 transcriptional activator FtrA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPEMSKMMTTLQRPLVIALAYDGLCTFEFGVAVEIFGLPRPELGDNWYRFAVAAVEPGALQATGGIHVVADGGLELLPNA
DMIIIPGWRGIDAKVPEMLCQSLREAHQRGTRLVSICSGVFVLAAAGLLHQRKATTHWRYTEQLQHRYPSISVSDNVLYQ
DEGQVMTSAGSAAGIDLCLHIVRKDFGHEIANNVARRLVIQPHRQGDQPQNLTRPMASPRESQTLGALFDFLQQNLAQTH
TVSSLAERVNMSPRTFLRRFEALTGMTPARWLLNERLIRVQDYLQNSVFNIEKIAELTGFGNSALLRHHFHQRFLLSPSQ
YRKNSRSPSQ
>SEQF1516_EDU86536.1 oxidoreductase, zinc-binding dehydrogenase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAAVVTKDHHVDVTDKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRA
SVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIR
PGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSRTEDAAKIVQEKTGGAHAAVVTAVAKA
AFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDGIEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTE
MEEGKIRGRMVIDFRR
>SEQF1516_EDU86537.1 DNA-damage-inducible protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKGSVPALQQEMLRRVSKRYDDVEVIIKSTSNDGLSVTRTADKDSAKTFVQETLKDTWESADEWFVR
>SEQF1516_EDU86538.1 oxidoreductase, zinc-binding dehydrogenase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLRTVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVS
RVVESNHPDYQSGDWVLGYSGWQDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
PVGATVGQIGKLKGCRVVGVAGGAEKCRHATEVLGFDVCLDHHADDFAEQLAKACPKGIDIYYENVGGKVFDAVLPLLNT
SARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKRIRLQGFIIAQDYGHRIHEFQREMGQWVKEDKIHYREEITDGLEN
APQTFIGLLKGKNFGKVVIRVAGDD
>SEQF1516_EDU86539.1 glutamate:gamma aminobutyrate antiporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVFFLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVS
NTLGPRWGFAAISFGYLQIAIGFIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGF
FAGILLPAFILIALAAIYLHSGAPVAIEMDSKTFFPDFSKVGTLVVFVAFILSYMGVEASATHVNEMSNPGRDYPLAMLL
LMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFTVLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTA
QKNLLPAAFAKMNKNGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVLVLKHPDLK
RTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLVVSFLVVLALPFILYAVHDRKGKANTGVTLE
PINSQNAPKGHFFLHPRARSPHYIVMNDKKH
>SEQF1516_EDU86540.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTYAVEFDNVSRLYGDVRAVDGVSIAIKDGEFFSMLGPSGSGKTTCLRLIAGFEQLSGGAISIFGKPASNLPPWERDVNT
VFQDYALFPHMSILDNVAYGLMVKGVNKKQRHAMAQEALEKVALGFVQQRKPSQLSGGQRQRVAIARALVNEPRVLLLDE
PLGALDLKLREQMQLELKKLQQSLGITFICVTHDQGEALSMSDRVAVFNNGRIEQVDSPRDLYMRPRTPFVAGFVGTSNV
FDGLMAEKLCGMTGSFALRPEHIRLNTPGELQANGTIQAVQYQGAATRFELKLNGGEKLLVSQANMTGEELPATLTPGQQ
VMVSWSRDVMVPLVEER
>SEQF1516_EDU86541.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLSLRRSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLIGYAMTIALTIGVVFSLGFGILADKFDKKRYMLLAI
TAFASGFIAIPLVNNVTLVVLFFALINCAYSVFATVLKAWFADNLSSTSKTKIFSINYTMLNIGWTVGPPLGTLLVMQSI
NLPFWLAAICSAFPMFFIQIWVKRSEKIIATETGSVWSPKVLLQDKALLWFTCSGFLASFVSGAFASCISQYVMVIADGD
FAEKVVAVVLPVNAAMVVTLQYSVGRRLNPANIRALMTAGTLCFVIGLIGFIFSGNSLLLWGMSAAVFTVGEIIYAPGEY
MLIDHIAPPGMKASYFSAQSLGWLGAAVNPLVSGVVLTTLPSSSLFIILALVIIAAWALMLKGINARPQRQPALC
>SEQF1516_EDU86542.1 putative prophage tail fibre C-terminus family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNILKKIMQRLCGCGKHDDRENGELLTAQLRLGPADILESDENGIIPEQDRVITQVVILDADKKQIQCVVRPLQILRADG
TWENIGGMK
>SEQF1516_EDU86543.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTHICARFIHLAGRPYMSLYQHMLFFYAVMAAIAFLITWFLSHDKKRIRFLSAFLVGATWPMSFPVALLFSLF
>SEQF1516_EDU86544.1 putative ABC transporter periplasmic-binding protein yddS precursor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRSISFRPTLLALVLATTFPVAHAAVPKDMLVIGKAADPQTLDPAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEG
DLASSWKASNDQKEWTFTLKDNAKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYPGNKPNFKRVSVKIIGESASRRL
QLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLRVTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMR
GPIPEGMWGYDATAMQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKLANATMRDR
VGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKLLRNALATTDQTQRTRDYQQAQKIVIDDAAY
VYLFQKNYQLAMNKEVKGFVFNPMLEQVFNINTMSK
>SEQF1516_EDU86545.1 TonB-dependent receptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIVFVRQTVLPALLVLSPVVFAADEQTMIVSAAPQVVSELDTPAAVSVVDGEEMRLATPRINLSESLTGVPGLQVQNRQ
NYAQDLQLSIRGFGSRSTYGIRGIRLYVDGIPATMPDGQGQTSNIDLSSVQNVEVLRGPFSALYGNASGGVMNVTTQTGQ
QPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDVDYTVSTTRFTTHGYRDHSGAQKNLANAKLGVRIDDASKLSLIFN
SVDIKADDPGGLTKAEWKANPQQAPRAEQYDTRKTIKQTQAGLRYERSLSSRDDMSVMMYAGERETTQYQSIPMAPQLNP
SHAGSVITLQRHYQGIDSRWTHRGELGVPVTFTTGLNYENMSENRKGYNNFRLNSGMPEYGQKGELRRDERNLMWNIDPY
LQTQWQLSEKLSLDAGVRYSSVWFDSNDHYVTPGNGDDSGDASYHKWLPAGSLKYAMTDAWNIYLAAGRGFETPTINELS
YRADGQSGMNFGLKPSTNDTIEIGSKTRIGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQRFAG
DFRVNASWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYVPEDGWYAGMEARYMGDIMADDENTAKAPSYTLVGL
FTGYKYNYHNLTVDLFGRVDNLFDKEYVGSVIVNESNGRYYEPAPGRNYGVGVNIAWRFE
>SEQF1516_EDU86546.1 enterobacterial Ail/Lom family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKLYAAILSAAICLAVSGAPAWASEQQATLSAGYLHARTSAPGSDNLNGINVKYRYEFTDTLGLVTSFSYAGDKNRQLT
RYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
GAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF
>SEQF1516_EDU86547.1 fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLKHVGMIVVSVLAMSSAAVSAAEGDESVTTTVNGGVIHFKGEVVNAACAIDSESMNQTVELGQVRSSRLAKAGDLSSA
VGFNIKLNDCDTNVSSNAAVAFLGTTVTSNDDTLALQSSAAGSAQNVGIQILDRTGEVLILDGATFSAKTDLIDGTNILP
FQARYIALGQSVAGTANADATFKVQYL
>SEQF1516_EDU86548.1 multiple antibiotic resistance protein MarB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPLLSAIAAALILFSAQGVAEQTQQPLVTSCGDVVVVPPSQEQPPFDLNHMGTGSDKSDALGVPYYNQQAM
>SEQF1516_EDU86549.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQPVLDIQQLHLSFPGFNGDVHALNNVSLQINRGEIVGLVGESGSGKSVTAMLIMRLLPTGSYCVHRGQISLLGDDVLN
AREKQLRQWRGARVAMIFQEPMTALNPTRRIGLQMMDVIRHHQPISRREARAKAIALLEEMQIPDTVEVMSRYPFELSGG
MRQRVMIALAFSCEPQLIIADEPTTALDVTVQLQVLRLLKHKARDSGTAVLFISHDMAVVSQLCDSVYVMYAGSVIESGV
TADVIHHPRHPYTIGLLQCAPEHGVPRQPLPAIPGTVPNLTHLPDGCAFRDRCYAAGAQCENVPALTACGDNNQRCACWY
PQQEVISV
>SEQF1516_EDU86550.1 sugar efflux transporter SotB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKL
LICLFVVFIASHVLSFLSWSFTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIV
GQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLTVVVVTAHYTAYSYIEPFVQNIA
GFSANFATALLLLLGGAGIIGSVIFGKLGNQYASALVSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQ
VKVLALAPDATDVAMALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGTVPAFAALIWSIIIFRRWPVTLEEQTQ
>SEQF1516_EDU86551.1 30S ribosomal protein, S22 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAEK
>SEQF1516_EDU86552.1 formate dehydrogenase, gamma subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLTQTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNI
PDKKDIPWLLNIVEVLKGNEHKVADVGKYNAGQKMMFWSIMSMIFVLLVTGVIIWRPYFAQYFPMQVVRYSLLIHAAAGI
ILIHAILIHMYMAFWVKGSIKGMIEGKVSRRWAKKHHPRWYREIEKAEAKKESEEGI
>SEQF1516_EDU86553.1 peroxiredoxin OsmC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIHKKGQAHWESDIKRGKGTVSTESGVLNQQPYGFNTRFEGEKGTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDT
TADVSLDKVDAGFAITKIALKSEVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLDYQLKS
>SEQF1516_EDU86554.1 hypothetical protein ECH7EC4501_2592 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQIARIKIPEINVSFFGLNSAGFSDYPTINSDSDIGGLESCC
>SEQF1516_EDU86555.1 hypothetical protein ECH7EC4501_2535 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKINVMELFFRHQKSNAASLLRLQAIAGNVKSFRNFIPS
>SEQF1516_EDU86556.1 protein HipA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEIGRDSVGAVTLIPEDETVTRPIMAWEKLTEVRLEEVLTAYKADIPLGMIREENDFRISVAGAQEKTALLRIGNDWCI
PKGITPTTHIIKLPIGEIRQPNATLDLSQSVDNEYYCLLLAKELGLNVPDAEIIKAGNVRALAVERFDRRWNAERTVLLR
LPQEDMCQTFGLPSSVKYESDGGPGIARIMAFLMGFSEALRDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTP
FYDIISAFPVLGGTGIHISDLKLAMGLNASKGKKTAIDKIYPRHFLATAKVLRFPEVQMHEILSDFARMIPAALDNVKTS
LPTDFPENVVTAVETNVLRLHGRLSREYGIK
>SEQF1516_EDU86557.1 transferase homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKVYGVPGWGSTISELMLTLADIPYQFVDVSGFDHEGTSRELLKTLNPLCQVPTLALENDEIMTETAAIALMVLDRRPD
LAPPVGRAERQQFQRLLVWLVANVYPTFTFADYPERWASDAPEQLKKNVIEYRKSLYVWLNSQLTAEPYAFGEQLTLVDC
YLCTMRTWGPGHEWFQDNATNISAIADAVCQLPTLQEILKRNEII
>SEQF1516_EDU86558.1 diguanylate cyclase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEMYFKRMKDEWTGLVEQADPPIRAKAAEIAVAHAHYLSIEFYRIVRIDPHAEEFLSNEQVERQLKSAMERWIINVLSAQ
VDDVERLIQIQHTVAEVHARIGIPVEIVEMGFRVLKKILYPVIFSSDYSAAEKLQVYHFSINSIDIAMEVMTRAFTFSDS
SASKEDENYRIFSLLENAEEEKERQIASILSWEIDIIYKILLDSDLGSSLPLSQADFGLWFNHKGRHYFSGIAEVGHISR
LIQDFDGIFNQTMRNTRNLNNRSLRVKFLLQIRNTVSQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHA
NRTGTPLSVLIIDVDKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLRTAERIRSR
VEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGRNRVELWKASL
>SEQF1516_EDU86559.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRETVEIMRYPVTLTPAPEGGYMVSFVDIPEALTQGETVAEAMEAAKDALLTAFDFYFEDNELIPLPSPLNSHDHFIEVP
LSVASKVLLLNAFLQSEITQQELARRIGKPKQEITRLFNLHHATKIDAVQLAAKALGKELSLVMV
>SEQF1516_EDU86560.1 respiratory nitrate reductase 2, gamma subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIQYLNVFFYDIYPYICATVFFLGSWLRYDYGQYTWRASSSQMLDKRGMVIWSNLFHIGILGIFFGHLFGMLTPHWMYAW
FLPVAAKQLMAMVLGGICGVLTLIGGAGLLWRRLTNQRVRATSTTPDIIIMSILLIQCLLGLSTIPFSAQYPDGSEMMKL
VGWAQSIVTFRGGSSEMLNGVAFVFRLHLVLGMTIFLLFPFTRLVHVWSAPFEYFTRRYQIVRSRR
>SEQF1516_EDU86561.1 glutaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVAMDNAILENILRQVRPLIGQGKVADYIPALATVDGSRLGIAICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHY
SEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARS
EFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPVVTPMQARQINALMAT
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAIAVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY
>SEQF1516_EDU86562.1 hypothetical protein ECH7EC4501_2646 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSQTNIHNVFLFTTINNLITIIEMNDDLYKEYTLPPHPDNMICTLPS
>SEQF1516_EDU86563.1 inner membrane ABC transporter ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITIPITFCMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILGVVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPA
LLGIFVLISVNKTWLIKLLTIRWREWLTDYYLNRWFADKNYYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQ
SLSMLITFTVILWQSAGMLSFTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRPLNVEKQRSEATFRTNLVQHNKQ
AELIALSNAESLQRQELSDNFHTIKENWHRLMNRQRWLDYWQNIYSRSLSVLPYFLLLPQFISGQINLGGLMKSRQAFML
VSNNLSWFIYKYDELAELAAVIDRLYEFHQLTEQRPTNKPKNCQHAVQVADASIRTPDNKIILENLNFHVSPGKWLLLKG
YSGAGKTTLLKTLSHCWPWFKGDISSPADSWYVSQTPLIKTGLLKEIICKALPLPVDDKSLSEVLHQVGLGKLAARIHDH
DRWGDILSSGEKQRIALARLILRRPKWIFLDETTSHLEEQEAIRLLRLVREKLPTSGVIMVTHQPGVWNLADDICDISAV
L
>SEQF1516_EDU86564.1 hypothetical protein ECH7EC4501_2649 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVITIILYGYKTIGAASYPLSINDAKHPLTILKGINTTDEKMTNPFAG
>SEQF1516_EDU86565.1 protein rhsD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGKPAARQGDMTQYGGPIVQGSAGVRIGAPTGVACSVCPGGMTSGNPVNPLLGAKVLPGETDLALPGPLPFILSRTYSS
YRTRTPAPVGIFGPGWKAPSDIRLQLRDDALVLNDNGGRSIHFEPLLPGEAVYSRSESMWLVRGGKAAQPDGHTLARLWG
ALPPDIRLSPHLYLATNSAQGPWWILGWSERVPGAEDVLPAPLPPYRVLTGMADRFGRTLTYRREAAGDLAGEITGVTDG
AGREFRLVLTTQAQRAEEARKQHTASLSSPDTPRPLSDSAFPDTLPGTEYGPDRGIRLSAVWLTHDPAYPESLPGAPLAR
YTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGLSYRYQYEQDRITVTDSL
NRREVLHTEGGAGLKRVVKKELADGSVTHSGYDAAGRLTAQTDAAGRRTEYGLNVVSGDITDITTPDGRETKFYYNDGNQ
LTAVVSPDGLESRRAYDEPGRLVSETSRCGDVIRYAYDNPHSELPATTTDATGSTRQMTWSRYGQLLAFTDCSGYQTRYE
YDRFGQMTAVHREEGISRYRRYDNRGRLTSVKDAQGHETRYEYNAAGDLTAVITPDGNRSETQYDAWGKAVSTTQGGLTR
SMEYDLAGRITTLTNENGSRSEFTYDALDRLVQQRGFDGRTQRYHYDLTGKLTQSEDEGLVTLWHYDESDRLTHRTVNGE
PAEQWQYDEHGWLTEISHLSEGHQVAVHYGYDDKGRLAGERQTVHNPETGELLWQHETEHAYNEQGLANRVTPDSLPRVE
WLTYGSGYLAGMKLGGTPLVEFTRDRLHRETVRSFGNNAYELTSTYTPAGHLQSQRLNSQVYDRDYDWNDNGDLVRISGP
RQTWEYGYSATGRLESVRTLASDLDIRIPYATDPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYRHDEYGRLTEKTDR
IPAGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRERDLTGWMSLSRKPEVTWYGWDG
DRLTTVQTDTTRIQTVYEPGSFTPLIRVETENGEREKAQRRSLAETLQQEGSENGHGVVFPAELVRLLDRLEEEIRADRV
SSESRAWLAQCGLTVEQLARQVEPEYTPARKVHFYHCDHRGLPLALISEDGNTAWRGEYDEWGNQLNEENPYYLHQPYRL
PGQQHDEESGLYYNRNRYYDPLQGRYITQDPIGLAGGWNLYNYPLNPIIRMDPLGLYNLYQLLYDVWHDDSYGTSSIDIT
GSGDLISLGGHAGLGVAFAKKKGEMLSDICIYATACGHAGIGGGINAAITYSETKSLPTSGVSNSVGVTVGGGVGGHFAY
TYVVDVDNPESSTESVGIGAGVDASVMTLACRTWQECWVN
>SEQF1516_EDU86566.1 fimbrial usher family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHQVLLLPRFARLTIALSLATAVFPVDAEYYFNPRFLSNDLAESVDLSAFTKGREAPPGTYRVDIYLNDEFMTSRDITFI
TDDNNADLIPCLSTDLLVSLGIKKSALLDNKEHSAEKHVPDNSACTPLQDRLVDASTEFDVGQQHLSLSVPQIYVGRMAR
GYVSPDLWEEGINAGLLNYSFNGNSINNRSNHNAGKSNYAYLNLQSGINIGSWRLRDNSTWSYNSGSSNSSDSNKWQHIN
TSAERDIIPLRSRLTVGDSYTDGDIFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIARGTAQVSVKQNGYDVYQTTVPP
GPFTIDDINSAANGGDLQVTIKEADGSIQTLYVPYSSVPVLQRAGYTRYALAMGEYRSGNNLQSSPRFIQGSLMHGLEGN
WTPYGGMQIAEDYQAFNLGIGKDLGLFGAFSFDITQANTTLADGTRHSGQSVKSVYSKSFYQTGTNIQVAGYRYSTQGFY
NLSDSAYSRMSGYTVKPPTGDSNEQTQFIDYFNLFYSKRGQEQISISQQLGNYGATFFSASRQSYWNTSRSDQQISFGLN
VPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFRNSNASYSMSNDLKGGMTNLSGVYGTLLPDNNL
NYSVQVGNTHGGNTSSGTSGYSTLNYRGAYGNTNVGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGAD
NVKIENQTGIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQIGGKVLMTLKYGNK
SVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGNDKNSNCIVDYKLPEVSPGTLLNQQTAICR
>SEQF1516_EDU86567.1 formate dehydrogenase, nitrate-inducible, iron-sulfur subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKACQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVM
RFSETEQSGKLEWLIRKDGCMHCEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKC
TLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEGVGGTHVMYVLHHADQPELYHGL
PKDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHYIGIGPNKEVDDDEEDHHE
>SEQF1516_EDU86568.1 hypothetical protein ECH7EC4501_2660 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGLFDVVILHAARTVREISALTVRKIISYSYDLQYYP
>SEQF1516_EDU86569.1 autoinducer-2 ABC transporter, ATP-binding protein LsrA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTSDTRALPLLCARSVYKQYSGVNVLKGIDFTLHQGEVHALLGGNGAGKSTLMKIIAGITSADSGTLEIGGNNYARLTP
VHAHQLGIYLVPQEPLLFPSLSIKENILFGLAKKQLSMQKMKNLLAALGCQFDLHSLAGSLDVADRQMVEILRGLMRDSR
ILILDEPTASLTPAETERLFTRLQELLATGVGIVFISHKLPEIRQIADRISVMRDGTIALSGKTSELSTDDIIQAITPAV
REKSLSASQKLWLELPGNRPQHAAGTSVLTLENLTGEGFRNVSLTLNAGEILGLAGLVGAGRTELAETLYGLRTLRGGRI
MLNDKEINRLSTGERLLRGLVYLPEDRQSSGLNLDASLAWNVCALTHNLRGFWAKTAKDNATLELYRRALNIKYNQPEQA
ARTLSGGNQQKILIAKCLEASPQVLIVDEPTRGVDVSARNDIYQLLRSIAAQNVAVLLISSDLEEIELMADRVYVMHQGE
ITHSALTGRDINVETIMRVAFGDSQRQEAAC
>SEQF1516_EDU86570.1 protein bdm [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTYYQAENSTAEPALVNAIEQGLRAEHGVVTEDDILMELTKWVEASDNDILSDIYQQTINYVVSGQHPTL
>SEQF1516_EDU86571.1 transcriptional regulator, GntR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVETQLNPTQPVNQQIYRILRRDIVHCLIAPGTPLSEKEVSVRFNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISM
AQVRNGSFIRQAIECAVARRAASMITESQCYQLEQNLHQQRIAIERKQLDDFFELDDNFHQLLTQIADCQLAWDTIENLK
ATVDRVRYMSFDHVSPPEMLLRQHLDIFSALQKRDGDAVERAMTQHLQEISESVRQIRQENSDWFSEE
>SEQF1516_EDU86572.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLTQLEMFNAVAEAGSITQAAAIVHRVPSNLTTRLRQLETELGVDLFIRENQRLRLSPAGHNFLRYSQQILALVDEARS
VVAGDEPQGLFSLGSLESTAAVRIPATLAEFNRRYPKIQFSLSTGPSGTMLEGVLEGKLNAAFIDGPINHTAIDGIPVYR
EELMIVTPQGHAPVIRASQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESYHGMLACVVAGAGIALIPRSMLE
SMPGHHQVEAWPLAEQWCWLTTWLVWRRGAKTRPLEAFIQLLDVPDSTKQGYQ
>SEQF1516_EDU86573.1 multiple antibiotic resistance protein MarC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNGAERNRQSLMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAG
GLIVAFIGFRMLFPQQKAIDSPEAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIKTNH
>SEQF1516_EDU86574.1 tagaturonate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDLNSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKG
EAVSDARLIRSVNREISVYSEYDEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGA
LDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTGYPRDEVAKLEEELGYHDGFLDT
AEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKPYKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKA
IYEEIIPVLDLPRDELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFALAALIAFY
RGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKDHWEQDLTQVPGLVEQVANDLDAILEKGMREAVR
PLC
>SEQF1516_EDU86575.1 hypothetical protein ECH7EC4501_2560 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAPRPMVNNNDEARRALVERRRDKFICLSGSAFRYVLF
>SEQF1516_EDU86576.1 peptidyl-dipeptidase Dcp [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTINPFLVQSTLPYLAPHFDQIANHHYRPAFDEGIQQKRAEIAAIALNPQTPDFNNTILALEQSGELLTRVTSVFFAMT
AAHTNDELQRLDEQFSAELAELANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKV
LNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWLIPLLNTTQQPALAEMRDRATRE
KLFIAGWTRAEKNDANDTRAIIQRLVEIRAQQATLLGFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQ
AVIDKQQGGFSAQPWDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYHPDVRVWEI
FDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNETHPVIYNVCNYQKPAAGEPALLLWDDVITLFHEFGHTLHGLF
ARQRYATLSGTNTPRDFVEFPSQINEHWATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAALLDMR
WHCLEENEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVEQGGLTRENG
LRFREAILSRGNSEDLERLYRQWRGKAPQIMPMLQHRGLNI
>SEQF1516_EDU86577.1 tautomerase enzyme family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIALQQIQPESWQAIWDAEIAPQMEALIKKPGYSM
>SEQF1516_EDU86578.1 autoinducer-2 ABC transporter, periplasmic autoinducer-2-binding protein LsrB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLHRFKKIALLSALGIAAISMNVQAAERIAFIPKLVGVGFFTSGGNGAQQAGKELGVDVTYDGPTEPSVSGQVQLINNF
VNQGYNAIIVSAVSPDGLCPALKRAMQRGVRVLTWDSDTKPECRSYYINQGTPAQLGGMLVDMAARQVNKDKAKVAFFYS
SPTVTDQNQWVKEAKAKIAKEHPGWEIVTTQFGYNDATKSLQTAEGILKAYSDLDAIIAPDANALPAAAQAAENLKNDKV
AIVGFSTPNVMRPYVERGTVKEFGLWDVVQQGKISVYVADALLKKGSMKTGDKLDIQGVGQVEVSPNSVQGYDYEADGNG
IVLLPERVIFNKENIGKYDF
>SEQF1516_EDU86579.1 autoinducer-2 ABC transporter, permease protein LsrC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKFIQNNREITALLAVLLLFVLPGFLDRQYLSVQTLTMVYSSAQILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGM
LLNAGYSLPVACVATLLLGLLAGFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKQLSAPLLLGVS
AIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMAALAGIVFASQIGFIPNQTGTGL
EMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQIDSVLVLLRIPAWWNDFIAGLVLLAVLVFDGRLRCALELNLRRQKY
ARFMTPPPSVKPASSGKKREAA
>SEQF1516_EDU86580.1 diguanylate cyclase (GGDEF) domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKKTTEIDAILLNLNKAIDAHYQWLVSMFHSVVARDASKPEITDNHSYGLCQFGRWIDHLRPLDNDELPYVRLMDSAHQ
HMHNCGRELMLAIVENHWQDAHFDAFQEGVLSFTAALTDYKIYLLTIRSNMDVLTGLPGRRVLDESFDHQLRNTEPLNLY
LMLLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEEFIIIVKAANDEEACRAGVRICQLVDNHAITH
SEGHINITVTAGVSRAFPEETLDVVIGRADRAMYEGKQTGRNRCMFIDEQNVINRV
>SEQF1516_EDU86581.1 sulfatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAFAAHAADDVKLKATKTNVAFSDFTPTEYSTKGKPNIIVLTMDDLGYGQLPFDKGSFDPKTMENREVVDTYKIGIDKA
IEAAQKSTPTLLSLMDEGVRFTNGYVAHGVSGPSRAAIMTGRAPARFGVYSNTDAQDGIPLTETFLPELFQNHGYYTAAV
GKWHLSKISNVPVPEDKQTRDYHDNFTTFSAEEWQPQNRGFDYFMGFHAAGTAYYNSPSLFKNRERVPAKGYISDQLTDE
AIGVVDRAKTLDQPFMLYLAYNAPHLPNDNPAPEQYQKQFNTGSQTADNYYASVYSVDQGVKRILEQLKKNGQYDNTIIL
FTSDNGAVIDGPLPLNGAQKGYKSQTYPGGTHTPMFMWWKGKLQPGNYDKLISAMDFYPTALDAADISIPKDLKLDGVSL
LPWLQDKKQGEPHKNLTWITSYSHWFDEENIPFWDNYHKFVRHQSDDYPHNPNTEDLSQFSYTVRNNDYSLVYTVENNQL
GLYKLTDLQQKDNLAAANPQVVKEMQGVVREFIDSSQPPLSEVNQEKFNNIKKALSEAK
>SEQF1516_EDU86582.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTPPAGSKPPATTQQSSQPMRGIWLATVSRLDWPPVSSVNISNPTSRARVQQQAMIDKLDHLQRLGINTVFFQVKPDGT
ALWPSKILPWSDLMTGKIGENPGYDPLQFMLDEAHKRGMKVHAWFNPYRVSVNTKPGTIRELNSTLSQQPASVYVQHRDW
IRTSGDRFVLDPGIPEVQDWITSIVAEVVSRYPVDGVQFDDYFYTESPGSRLNDNETYRKYGGAFASKADWRRNNTQQLI
AKVSHTIKSIKPGVEFGVSPAGVWRNRSHDPLGSDTRGAAAYDESYADTRRWVEQGLLDYIAPQIYWPFSRSAARYDVLA
KWWADVVKPTRTRLYIGIAFYKVGEPSKIEPDWMINGGVPELKKQLDLNDAVPEISGTILFREDYLNKPQTQQAVSYLQS
RWGS
>SEQF1516_EDU86583.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTYDRNRNAITTGSRVMVSGTGHTGKILSIDTEGLTAEQIRRGKTVVVEGCEEKLAPLDLIRLGMN
>SEQF1516_EDU86584.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQSLTLAFLIAAGIGLVVQNSLMVRITQTSSTILIAMLLNSLVGIVLFVSILWFKQGMAGFGELVSSVRWWTLIPGLLG
SFFVFASISGYQNVGAATTIAVLVASQLIGGLVLDIFRSHGVPLRALFGPICGAILLVVGAWLVARRSF
>SEQF1516_EDU86585.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALERQLNGGVDFLSSVNNYFQSVMAEHRENKTGNKILMEKINSCVFGTDSNHFSCPESFLTCPITLDTPETGVFMRNSR
GAEICSLYDKDALVQLVETGGTHPLSREPITESMIMRKDECHFDAKREAFCCK
>SEQF1516_EDU86586.1 multiple antibiotic resistance protein MarA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYL
AERYGFESQQTLTRTFKNYFDVPPHKYRMTNMQGESRFLHPLNHYNS
>SEQF1516_EDU86587.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNKITQRDNYKEIMSVIVVILLLTLTLIAIFSAIDQLGISEMGRIARDLTHFIVNSLQD
>SEQF1516_EDU86588.1 malate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIQKRVSDMEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLGLLPEVVETIEEQAERAWIQYQGFKTEI
DKHIYLRNIQDTNETLFYRLVNNHLDEMMPVIYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIV
VTDGERILGLGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRITDDEYYEFVDEFI
QAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAAVTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIA
EMIIAQTQREGLSEEAARQKVFMVDRFGLLTDKMPNLLPFQTKLVQKRENLSDRDTDSDVLSLLDVVRNVKPDILIGVSG
QTGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVVWKDKIYPIAQCNNAFIFPGIG
LGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLVLPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDN
FWQAEYRDYRRTSI
>SEQF1516_EDU86589.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGHKGHEFVWVKNVDHQLRHEADSDELRAVAEESAEGLREHFYWQKSRKPEAGQR
>SEQF1516_EDU86590.1 nitrate reductase 2, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTGREGMEYAWFNNVETKPGIGYPKNWEDQEEWQGGWVRDVNGKIRPRLGS
KMGVITKIFANPVVPQIDDYYEPFTFDYEHLHSAPEGKHIPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNF
EAMQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRGWRLCISGCPYKKIYFNWKSGKS
EKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDADRIEEAASTEREVDLYERQCEVFLDPHDPSVIEEALKQGIPQNV
IDAAQRSPVYKMAMDWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPKSEGVLPAIESLRIPVQYLANMLSAGDTG
PVLRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSIAQVEEMYRYLAIANYEDRFVIPTSHREMAGDAFAERNGCGFTF
GDGCHGSDSKFNLFNSSRIDAINITEVRDKAEGE
>SEQF1516_EDU86591.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHLDEVIARVDAAIEESVIAHMNELLIALSDDAELSREDRYTQQQRLRTAIAHHGRKHKEDMEARHEQLTKGGTIL
>SEQF1516_EDU86592.1 radical SAM domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEIAMHVTAKPSSFQCNLKCDYCFYLEKESQFTHEKWMDDSTLKEFIKQYIAASGNQVYFTWQGGEPTLAGLDFFRKVI
HYQQRYAGQKRIFNALQTNGILLNNEWCAFLKEHEFLVGISIDGPQELHDRYRRSNSGNGTFAKVIAAIERLKSYQVEFN
TLTVINNVNVHYPLEVYHFLKSIGSKHMQFIELLETGTPNIDFSGHSENTFRIIDFSVPPTAYGKFMSTIFMQWVKNDVG
EIFIRQFESFVSRFLGNGHTSCIFQESCKDNLVVESNGDIYECDHFVYPQYKLGNINKSELKTMNSVQLTAQKKRISAKC
QQCAYKPICNGGCPKHRITKVNDETVSYFCEGYKILFSTMVPYMNAMVELAKNRVPLYHIMDVAKQMENN
>SEQF1516_EDU86593.1 nitrate reductase 2, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKLLDRFRYFKQKGDTFADGHGQVMHSNRDWEDSYRQRWQFDKIVRSTHGVNCTGSCSWKIYVKNGLVTWEIQQTDYPR
TRPDLPNHEPRGCPRGASYSWYLYSANRLKYPLIRKRLIELWREALKQHSDPVLAWASIMNDPQKSLSYKQVRGRGGFIR
SNWPELNQLIAAANVWTIKTYGPDRVAGFSPIPAMSMVSYAAGTRYLSLLGGTCLSFYDWYCDLPPASPMTWGEQTDVPE
SADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTKTIAITPDYSEVAKLCDQWLAPKQGTDSALAMAMGHVILKEFHL
DNPSDYFINYCRRYSDMPMLVMLEPRDDGSYVPGRMIRASDLVDGLGESNNPQWKTVAVNTAGELVVPNGSIGFRWGEKG
KWNLESIAAGKETELSLTLLGQHDAVAGVAFPYFGGIENPHFRSVKHNPVLVRQLPVKNLTLAGGSTCPVVSVYDLVLAN
YGLDRGLEDENSAKDYAEIKPYTPAWGEQITGVPRQYIETIAREFADTAHKTHGRSMIILGAGVNHWYHMDMNYRGMINM
LIFCGCVGQSGGGWAHYVGQEKLRPQTGWLPLAFALDWNRPPRQMNSTSFFYNHSSQWRYEKVSAQELLSPLADASKYSG
HLIDFNVRAERMGWLPSAPQLGRNPLGIKAEADKAGLSPTEFTAQALKSGDLRMACEQPDSGSNHPRNLFVWRSNLLGSS
GKGHEYMQKYLLGTESGIQGEELGASDGIKPEEVEWQTAAIEGKLDLLVTLDFRMSSTCLFSDIVLPTATWYEKDDMNTS
DMHPFIHPLSAAVDPAWESRSDWEIYKGIAKAFSQVCVGHLGKETDVVLQPLLHDSPAELSQPCEVLDWRKGECDLSPGK
TAPNIVAVERDYPATYERFTSLGPLMDKLGNGGKGISWNTQDEIDFLGKLNYTKRDGPAQGRPLIDTAIDASEVILALAP
ETNGHVAVKAWQALGEITGREHTHLALHKEDEKIRFRDIQAQPRKIISSPTWSGLESDHVSYNAGYTNVHELIPWRTLSG
RQQLYQDHPWMRAFGESLVAYRPPIDTRSVSEMRQIPPNGFPEKALNFLTPHQKWGIHSTYSENLLMLTLSRGGPIVWIS
ETDARELTIVDNDWVEVFNANGALTARAVVSQRVPPGMTMMYHAQERIMNIPGSEVTGMRGGIHNSVTRICPKPTHMIGG
YAQLAWGFNYYGTVGSNRDEFIMIRKMKNVNWLDDEGRDQVQEAKK
>SEQF1516_EDU86594.1 autoinducer-2 ABC transporter, permease protein LsrD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIRYGWELALAALLVIEIVSFGAINPRMLDLNMLLFSTSDFICIGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLF
QSGVPMPLAILLTLLLGALCGLINAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDV
LGLPVPLIIFLICLLVFWLWLHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMTGLASAVAAVLLVSYFGSARSDL
GASFLMPAITAVVLGGANIYGGSGAIIGTAIAVLLVGYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEW
LARRANNPLP
>SEQF1516_EDU86595.1 inner membrane metabolite transport protein ydfJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFQLYSLGAALVFHEIFFPESSTAMALILAMGTYGAGYVARIVGAFIFGKMGDRIGRKKVLFITITMMGICTTLIGVLP
TYAQIGVFAPILLVTLRIIQGLGAGAEISGAGTMLAEYAPKGKRGIISSFVAMGTNCGTLSATAIWAFMFFILSKEELLA
WGWRIPFLASVVVMVFAIWLRMNLKESPVFEKVNDSNQPTAKPAPAGSIFQSKSFWLATGLRFGQAGNSGLIQTFLAGYL
VQTLLFNKAIPTDALMISSIPGFMTIPFLGWLSDKIGRRIPYIIMNTSAIVLAWPMLSIIVDKSYAPSTIMVALIVIHNC
AVLGLFALENITMAEMFGCKNRFTRMAISKEIGGLIASGFGPILAGIFCTMTESWYPIAIMIMAYSVIGLISALKMPEVK
DRDLSALEDAAEDQPRVVRAAQPSRSL
>SEQF1516_EDU86596.1 protein YdeP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKGNIGKPGAGICPLRGHSNVQGDRTVGITEKPSVEFLARLGERYGFTPPHVPGHAAIASMQAICTGQARALICMGGNF
ALAMPDREASAVPLTQLDLAVHVATKLNRSHLLTARHSYILPVLGRSEIDMQKSGAQAVTVEDSMSMIHASRGVLKPAGV
MLKSECAVVAGIAQATLPQSVVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANFIT
SKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAKICRVKNGERVNLIALTPDGKRSSR
RMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHDPLSGIPGYKSIPVELEPSN
>SEQF1516_EDU86597.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLSGLLLIFTVGFPRIRQIPKGYLLAGSLLFVSYEICLA
LSLGYAATRHQAIEVGMVNYLWPSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYF
LAFIGAFIWAAYCTVTNKYARGFNGITVFVLLTGASLWVYYFLTPQPEMVFSTPVMIKLISAAFTLGFAYAAWNVGILHG
NVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGALMVCGGSLLCWLATRRG
>SEQF1516_EDU86598.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSLDPLFARLSRSKFRSRFRLGMKERQYCLEKGAPVIEQHAADFVAKRLAPALPANDGKQTPMRGHPVFIAQHATATCC
RGCLAKWHNIPHGVSLSEEQQRYIVAVIYHWLVVQMNQP
>SEQF1516_EDU86599.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHLRHLFSLRLRGSLLLGSLLVASSFSTQAAEEMLRKAVGKGAYEMAYSQQENALWLATSQSRKLDKGGVVYRLDPVTLE
VTQAIHNDLKPFGATINNTTQTLWFGNTVNSAVTAIDAKTGEVKGRLVLDDRKRTEEVRPLQPRELVADDATNTVYISGI
GKDSVIWVVDGENIKLKTAIQNTGKMSTGLALDSKGKRLYTTNADGELITIDTADNKILSRKKLLDDGKEHFFINISLDT
ARQRAFITDSKAAEVLVVDTRNGNILAKVAAPESLAVLFNPARNEAYVTHRQAGKVSVIDAKSYKVVKTFDTPTHPNSLA
LSADGKTLYVSVKQKSTKQQEATQPDDVIRIAL
>SEQF1516_EDU86600.1 addiction module antidote protein, HigA family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKMANHPRPGDIIQESLDELNVSLREFARAMEIAPSTASRLLTGKAALTPEMAIKLSVVIGSSPQMWLNLQNAWSLAEAA
KTVDVSRLRRLVAQ
>SEQF1516_EDU86601.1 tail fiber protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVKISGVLKDGTGKPVENCTIQLKARRNSATVVVNTVASENPDEAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYED
SQPGTLNDFLGAMSEDDVRPEALRRFELMVEEAARHAEEAKKNAGEAETSARNAGISASQAEESAANADTSAGDASESAR
QAAESAAAAKQSEEASSSSASAAAQKASESSQSAADAELSKKTAESAAGNAARDATTATEKARESAESAQSAEQSRIAAE
EAVNRIPTVVGPPGPKGEPGPAGPQGPKGDKGERGDTGPAGATGERGPAGDAGPAGPAGPAGPQGPKGETGAAGPVGATG
PQGPKGDPGETQIRFRLGPGNIIETNSHGWFPDTDGALITGLTFLDPKDATRVQGFFQHLQVRFGDGPWQDVKGLDEVGS
DTGRTGE
>SEQF1516_EDU86602.1 autoinducer-2 kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARLFTPSESKYYLMALDAGTGSIRAVIFDLEGNQIAVGQAEWRHLAVPDVPGSMEFDLNKNWQLACECMRQALHNAGIA
PEYIAAVSACSMREGIVLYNNEGTPIWACANVDARAAREVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRSD
IYRQASTITMISDWLAYMLSGELAVDPSNAGTTGLLDLTIRDWKPALLDMAGLRADILSPVKETGTLLGVVSSQAAELCG
LKVGTPVVVGGGDVQLGCLGLGVVRPAQTAVLGGTFWQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRW
FRDAFCAEEKLIAERLGIDTYTLLEEMASRVPPGSWGVMPIFSDRMRFKTWYHAAPSFINLSIDPDKCNKATLFRALEEN
AAIVSACNLQQIADFSTIHPSSLVFAGGGSKGKLWSQILADVSGLPVNIPVVKEATALGCAIAAGVGAGIFSSMAETGER
LVRWERTHTPDPEKHELYQDSRDKWQAVYQDQLGLVDHGLTTSLWKAPGL
>SEQF1516_EDU86603.1 glutamate decarboxylase GadB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKKQVTDLRSELLDSRFGAKSISTIAESKRFPLHEMRDDVAFQIINDELYLDGNARQNLATFCQTWDDENVHKLMDLSI
NKNWIDKEEYPQSAAIDLRCVNMVADLWHAPAPKNGQAVGTNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCG
PVQICWHKFARYWDVELREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADTGIDIDM
HIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHKFGLAPLGCGWVIWRDEEALPQELVFNVDYLGGQIGTFAINFSRP
AGQVIAQYYEFLRLGREGYTKVQNASYQVAAYLADEIAKLGPYEFICTGRPDEGIPAVCFKLKDGEDPGYTLYDLSERLR
LRGWQVPAFTLGGEATDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSDHPKLQGIAQQNSFKHT
>SEQF1516_EDU86604.1 putative ABC transport system ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDTLLTLRDVHINFPARKNWLGKTTEHVHAINGIDLQIRRGETLGIVGESGCGKSTLAQLLMGMLQPSHGQYIRSGSQR
IMQMMFQDPLSSLNPRLPVWRIITEPLWIAKHSSEQQRRALAEELAVQVGIRPEYLDRLPHAFSGGQRQRIAIARALSSQ
PDVIVLDEPTSALDISVQAQILNLLVTLQENHGLTYVLISHNVSVIRHMSDRVAVMYLGQIVELGEAQQVLTAPAHPYTR
LLLDSLPAIDKPLEEEWALRKTDLPGNRTLPQGCFFRERCPLATSGCEVRQSLTTRADGREIRCWRAL
>SEQF1516_EDU86605.1 ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMNVLQSPSRPGLGKVSGFFWRNPGLGLFLLLLGPLMWFGIVYFGSLLTLLWQGFYTFDDFTMSVTPELTLANIRALFN
PANYDIILRTLTMAVAVTIASAILAFPMAWYMARYTSGKMKAFFYIAVMLPMWASYIVKAYAWTLLLAKDGVTQWFLQHL
GLEPLLTAFLTLPAVGGNTLSTSGLGRFLVFLYIWLPFMILPVQAALERLPPSLLQASADLGARPRQTFRYVVLPLAIPG
IAAGSIFTFSLTLGDFIVPQLVGPPGYFIGNMVYSQQGAIGNMPMAAAFTLVPIVLIALYLAFVKRLGAFDAL
>SEQF1516_EDU86606.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLTSDIRSHSFNLGVEVVRARIVANGRGDITVGGETVSIVYDSTNGRFSSSGGNGGLLSELLLLGFNSGPRALGERMLS
MLSDSGEAQSQESIQNKISQCKFSVCPERLQCPLEAIQCPITLEQPEKGIFVKNSDGSDVCTLFDAAAFSRLVGEGLPHP
LTREPITASIIVKHEECIYDDTRGNFIIKGN
>SEQF1516_EDU86607.1 D-alanyl-D-alanine dipeptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHKDAITALAKSISIAQLSGLQLVIYDAYRPQQAQAMLW
QACPDPQYVVDVTVGSNHSRGTAIDLTLRDEHGNILDMGAGFDEMHERSHAYHPSVPPAAQRNRLLLNAIMTGGGFVGIS
SEWWHFELPQAASYPLLADQFTCFISPGTQHVS
>SEQF1516_EDU86608.1 rhodanese domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRYVTEFTTAKPEVAEAHFLARLSVETDCADVHDSLAYIGDDFVLLHVVGREEDFARRHIPGALHLPHKQMTAERMAEWP
DDTLFVVYCAGPHCNGADRAALKLARLGKPVKIMLGGITGWEDEGYAFASE
>SEQF1516_EDU86609.1 trans-aconitate 2-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDWNPSLYLHFAAERSRPAVELLARVPLENVDYVADLGCGPGNSTALLHQRWPAARITGIDSSPAMIAEARSALPDCQF
VEADIRNWQPEQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGRESLA
GVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFLTRYHQMLKEQYPLQENGQILLA
FPRLFIVARRTE
>SEQF1516_EDU86610.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLCFLIYITLPFIQLVYFISSEKKLTIHIVQMFHLLSQVFYNLKMFLMMDMLGVGDAININTNKNIRQVC
>SEQF1516_EDU86611.1 leucine-rich repeat protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFPSIFNKIKPQSIQQHPEKNQLNWMLELNKWKEERILTGEIHRPECRNEAAKRINCAFLSKQNDIDLSGLNLSTQPPG
LQNFTSINLDNNQLTHFDATNYDRLVKLSLNSNTLESINIHQGRNVSITHISMNNNCLRNIDIDRLSSITYFSAAHNKLE
FVQLESCEWLQYLNLSHNQLTDIVTGNKEELLLLDLSHNKLASLHNALFPNLNTLLINNNLLSEIKMFYSNFCKVQTLNA
ANNQLEKINLHFLTYLSSIKSLRLDNNKITRIDTENTSDIRSLFPIIKKSESLNFLNISGENNCPTIQLMLFNLFSPALK
LNTGLAILSPGAFEDHSDGLDVDNELFHYTINKAYTPYNIHTYKTEEVVNQRNIKIKNMTLDEINNTYCNNDYYNEAIRE
EPIDFLDRSFSSSSWPFYH
>SEQF1516_EDU86612.1 gamma-aminobutyraldehyde dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAAVRAADAAFAEWGQTTPKVRAECLLKLADVIEENGQV
FAELESRNCGKPLHSAFNDEIPAIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLA
PALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINVLFGRGKTVGDPLTGHPKVRMVSLTGSIATGEHIISHTAPSI
KRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNAGQDCTVACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTELG
PLSSLAHLERVSKAVEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTLFDNEEQVVNWAN
DSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLSGYGKDMSLYGLEDYTVVRHVMVKH
>SEQF1516_EDU86613.1 transporter, 10 TMS drug/metabolite exporter (DME) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFRGGRMSRKDGVLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVAFPAIFFVARPKVPLNLLLGYGLTISFAQF
AFLFCAINFGMPAGLASLVLQAQAFFTIVLGAFTFGERLHGKQLAGIALAISGVLVLIEDSFNGQHVAMLGFMLTLAAAF
SWASGNIFNKKIMSHSSRPAVMSLVVWSALIPIIPFFVASLILDGSGKMIHSLVTIDMTTILALMYLAFVATIVGYGIWG
TLLGRYETWRVAPLSLLVPVVGLASAALLLDERLTGLQFLGAVLIMAGLYINVFGLQWRKAVKVRG
>SEQF1516_EDU86614.1 competence/damage-inducible protein CinA C-terminal domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNINRNKIVQLADTDTIENLTSALSQRLIADQLRLTTAESCTGGKLASALCAAEDTPKFYGAGFVTFTDQAKMKILSVSQ
QSLERYSAVSEKVAAEMATGAIERADADVSIAITGYGGPEGGEDGTPAGTVWFAWHIKGQNYTAVMHFAGDCETVLALAV
RFALAQLLQLLL
>SEQF1516_EDU86615.1 lsrG protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHVTLVEINVHEDKVDEFIEVFRQNHLGSVQEEGNLRFDVLQDPEVNSRFYIYEAYKDEDAVAFHKTTPHYKTCVAKLES
LMTGPRKKRLFNGLMP
>SEQF1516_EDU86616.1 peptidase, U32 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKIAAIFQLLDKNVTVSSHRLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNASNSLKDIAELVPFAHRYGAKIF
VTLNTILHDDELEPAQRLITDLYQTGVDALIVQDMGILELDIPPIELHASTQCDIRTVEKAKFLSDVGFTQIVLARELNL
DQIRAIHQATDATIEFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLSMKDNDQTA
NLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEERGDLARASSGRTEHFFVPSTEKTFHRGSTDYFVNARKG
DIGAFDSPKFIGLPVGEVVKVAKDHLDVAVTEPLANGDGLNVLIKREVVGFRANTVEKTGENQYRVWPNEMPADLHKIRP
HHPLNRNLDHNWQQALTKTSSERRVAVDIELGGWQEQLILTLTSEEGVSITHTLDGQFDEANNAEKAMNNLKDGLAKLGQ
TLYYARDVQINLPGALFVPNSLLNQFRREAADMLDAARLASYQRGSRKPVADPAPVYPQTHLSFLANVYNQKAREFYHRY
GVQLIDAAYEAHEEKGEVPVMITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVNGDEVLTLKFDCRPCEMHVIGKIKNHI
LKMPLPGSVVASVSPDELLKTLPKRKG
>SEQF1516_EDU86617.1 ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPPQGLTLRWFSVAAQRSDILDAVTLSLKVAALATLMAL
VLGTLAAAALWRRDFFGKNAISLLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTLPLWLLNQLGRPRDVPVTNVVAL
LVMLVTTLPILGAWWLTREGDNGQ
>SEQF1516_EDU86618.1 transcriptional repressor LsrR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTINDSVISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTRLKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRR
QFSLQHVRVIPGLADADVGGRLGIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGI
GQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDDATIIRSGYISQGEQLMIGRKGA
VGDILGYFFDAKGDVVTDIKIHNELIGLPLSALKTIPVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS
>SEQF1516_EDU86619.1 aldehyde dehydrogenase (NAD) family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTITPATHAISINPATGEQLSVLPWAGADDIENALQLAAAGFRDWRETNIDYRAEKLRDIGKALRARSEEMAQMITREMG
KPINQARAEVAKSANLCDWYAEHGPAMLKAEPTLVENQQAVIEYRPLGTILAIMPWNFPLWQVMRGAVPIILAGNGYLLK
HAPNVMGCAQLIAQVFKDAGIPQGVYGWLNADNDGVTQMIKDSRIAAITVTGSVRAGAAIGAQAGAALKKCVLELGGSDP
FIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFIIEEGIASAFTERFVAAAAALKMDDPRDEENALGPMARFDLRDELH
HQVEKTLAQGARLLLGGEKMAGAGNYYPPTVLANVTPEMTAFREEMFGPVAAITIAKDAEHALELANDSEFGLSATIFTT
DETQARQMAARLECGGVFINGYCASDARVAFGGVKKSGFGRELSHFGLHEFCNIQTVWKDRI
>SEQF1516_EDU86620.1 periplasmic pilus chaperone family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTTRTPYSISFMATVLLLLLFACHSTVANAAVALGATRVIYPANQKQVLLPVTNNDPASVYLIQSWIENAGDQKDTQFV
ITPPLFSMQGKKENTLRIINATNHQLPGDRESLFWVNVKAIPAMEKDQKNENTLQLAIISRIKMFYRPTNLAMAPEEAPA
MLRFRRSGSNLTLINPTPYFITVTNMKAGNSNLPNTMVPPKGEVSVDIPHAATGDISFQTINDYGALTPRIKATMQ
>SEQF1516_EDU86621.1 phenazine biosynthesis protein PhzF family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPQVYHVDAFTSQPFRGNSAGVVFPADNLSEAQMQLIARELGHSETAFLLHSDDSDVRIRYFTPTVEVPICGHATVAAH
YVRAKVLGLGNCTVWQTSLAGKHRVTIEKHHDGYRISLEQGTPGFEPPLEGETRAAIINALHLTEDDILPGLPIQVATTG
HSKVMIPLKPEVDIDALSPDLNALTAISKQIGCNGFFPFQIRPGKNETDGRMFSPAIGIVEDPVTGNANGPMGAWLVHHN
VLPHDGNVLRVKGHQGRALGRDGMIEVTVTIRDNQPEKVTISGAAVILFHAEWAIKL
>SEQF1516_EDU86622.1 type VI secretion system Vgr family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTGLRFTLEVDGLPPDAFAVVSFHLNQSLSSLFSLDLSLVSQQFLSLEFAQVLDKMAYLTVWQGDDVQRRVKGVVTWFE
LGENDKNQMLYSMKVCPPLWRTGLRQNFRIFQNEDIESILATILKENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
AAEEGIFFYEEHAQKSIDQSLVLCDTVRYLPESFEIPWNPNTRTEVSTLCISQFRYSAQIRPSSVVTKDYTFKRPGWAGR
FDQEGQYQDYQRTQYEVYDYPGRFKGAHGQNFARWQMDGWRNNAEVARGTSRSPEIWPGRRIVLTGHPQANLNREWQVVA
SELHGEQPQAVPGRRGSGTTLNNHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRVRVKFNWDRYNPS
NQDSSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTYHQENRTPGSLPGTKTQMTIRSKNYKGSGFN
ELKFDDATGKEQVYIHAQKNMNTEVLNNRTTDVINNHAETIGNNQMIAVTNNQIQTVGVNQIETVGSNQIINVGSVQVET
IGLVRALTVGVAYQTTVGGIMNTSVALMQSSQIGLHKSLRVGLGYDVKVGNNVTFTVGKTKKDDTGQTAIYSAGEHLELC
CGKARLVLTKDGQIFLNGTKIHLQGKEQVNGDSLLINWNCAASKSPPKTPDEKQDTPDMREY
>SEQF1516_EDU86623.1 L-asparagine permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKHDTDTSDQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALALVYLICGLFSFFILRA
LGELVLHRPSSGSFVSYAREFLGEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNM
IGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQPLDGNTTGFHLITDNGGFFPHGLLPALVLIQGVVFAFASIEMVG
TAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLVMLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLN
SGLYCTGRILRSMAMGGSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIIVCQ
MRLRKAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYTIAALPIIGILLVIGWFGVRKRVAEIHSTAP
VVEEDEEKQEIVFKPETAS
>SEQF1516_EDU86624.1 transcriptional regulator, GntR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPGTEKMKHVSLTLQVENDLKHQLSIGALKPGARLITKNLAEQLGMSITPVREALLRLVSVNALSVAPAQAFTVPEVGKR
QLDEINRIRYELELMAVALAVENLTPQDLAELQELLEKLQQAQEKGDMEQIINVNRLFRLAIYHRSNMPILCEMIEQLWV
RMGPGLHYLYEAINPAELREHIENYHLLLAALKAKDKEGCRHCLAEIMQQNIAILYQQYNR
>SEQF1516_EDU86625.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPWYTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYV
EARKLWGQLMIASRSLLREVKTTLPDSASVREFARLQIAFAHCLRMTLRKQPQVEVLAHYLKTEDLQRVLASNSPANRIL
LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTVYLFCIMLPFALVVDLHYMTPFI
SVLISYTFISLDCLAEELEDPFGTENNDLPLDAICNAIEIDLLQMNDEAEIPAKVLPDRHYQLT
>SEQF1516_EDU86626.1 protein FimF homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYNNIIFLGLCLGLTTYSALSADSVIKISGRVLDYGCTVSSDSLNFTVDLQKNSARQFPTTGSTSPAVPFQITLSECSK
GTTGVRVAFNGIEDAENNTLLKLDEGSNTASGLGIEILDGNMRPVKLNDLHAGMQWIPLVPEQNNILPYSARLKSTQKSV
NPGLVRASATFTLEFQ
>SEQF1516_EDU86627.1 bacteriophage lambda tail assembly protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTAAEAIRALSLQMPGFRRQMNEGWYQIRIRGEDTAPEAVYARLHEPLGEGAVIHIVPRLAGAGKGGLQIVLGAAAIVG
SFFTAGASMALWGSALAAGGFSATTMLFSLGASMILGGVAQMLAPKAKTPDYRATDNGKQNTYFSSLDNMIAQGNPMPVP
YGEMLVGSRRISQDISTRDEGGDGKVVVIGRG
>SEQF1516_EDU86628.1 NADP-dependent l-serine/l-allo-threonine dehydrogenase ydfg [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQLDVRNRAAIEEMLASLPAEWCNIDILVN
NAGLALGMEPAHKASIEDWETMIDTNNKGLVYMTRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWWVSTLPAHVNINTLEMMPVTQSY
AGLNVHRQ
>SEQF1516_EDU86629.1 transcriptional regulator, GntR family/aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVSHAYQLLESQGYIIARPQSGYYVAPQAIKMPKVPVIP
VTRDEAVDINTYIFDMLQASRDPSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSVATDVKEGIDLQALELALQEYPV
KACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTLIEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRI
GWVAAGKHARKIQRLQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKIHHNDSGYF
LWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWLWGEREEQAVKQLGKLIQERL
>SEQF1516_EDU86630.1 ABC transporter, periplasmic substrate-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKTFARSSLCALSMTIMTAHAAEPPTNLDKPEGRLDIIAWPGYIERGQTDKQYDWVTQFEKETGCAVNVKTAATSDEMV
SLMTKGGYDLVTASGDASLRLIMGKRVQPINTALIPNWKTLDPRVVKGDWFNVGGKVYGTPYQWGPNLLMYNTKTFPTPP
DSWQVVFVEQNLQDGKSNKGRVQAYDGPIYIADAALFVKATQPQLGISDPYQLTEEQYQAVLKVLRDQHSLIHRYWHDTT
VQMSDFKNEGVVASSAWPYQTNALKAEGQPVATVFPKEGVTGWADTTMLHSEAKHPVCAYKWMNWSLTPKVQGDVAAWFG
SLPVVPEGCKASSLLGEKGCETNGFNYFDKIAFWKTPIAEGGKFVPYSRWTQDYIAIMGGR
>SEQF1516_EDU86631.1 TonB-dependent receptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRVLIPGVILCGADVAQAVDDKNMYMHFFEEMTVYAPVPVPVNGNTHYTSESIERLPTGNGNISDLLRTNPAVRMDSTQ
STSLNQGDIRPEKISIHGASPYQNAYLIDGISATNNLNPANESDASSATNISGMSQGYYLDVSLLDNVTLYDSFVPVEFG
RFNGGVIDAKFKRFNADDSSVKLGYRTTRSDWLTSHINENNKSAFNQGSSGSTYYSPDFKKNFYTLSFNQELADNFGVTA
GLSRRQSDITRADYVSNDGIVAGRAQYKNVIDTALSKFTWFASDRFTHDLTLKYTGSSRDYNTSTFPQSDREMGNKSYGM
AWDMDTQLAWAKLRTTVGWDHISDYTRHDHDIWYTELSCTYGDITGRCTRGGLGHISQAVDNYTFKTRLDWQKFAVGNVS
HQPYFGAEYIYSDAWTERHNQSESYVINAAGKKTNHTIYHKGKGSLGIDNYTLYMADRISWRNVSLMPGVRYDYDNYLSN
HNISPRFMTEWDIFADQTSMITAGYNRYYGGNILDMGLRDIRNSWTESVSGNKTLTRYQDLKTPYNDELAMGLQQKIGKN
VIARANYVYREAHDQISKSSRTDSATKTTITEYNNDGKTKTHSFNLSFELAEPLHISQVDINPQIVFSYIKSKGNLSLNN
GYEESNTGDNQVVYNGNLVSYDSVPVADFNNPLKISLNMDFTHQPSGLVWANTLAWQEARKARIILGKTNAQYISEYSDY
KQYVDEKLDSSLTWDTRLSWTPQFLKQQNLTISADILNVLDSKTAVDTTNTGVATYASGRTFWLDVSMKF
>SEQF1516_EDU86632.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFQAIVLASFLVIPYALADDQGGLKQDAAPPPPHAIEDGYRGTDDAKKMTVDFAKTMHDGASVSLRGNLISHKGEDRYV
FRDKSGEINVVIPATVFDGREVQPDQMINISGSLDKKSAPAVVRVTHLQK
>SEQF1516_EDU86633.1 lsrF protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADLDDIKDGKDFRTDQPQKNIPFTLKGCGALDWGMQSRLSRIFNPKTGKTVMLAFDHGYFQGPTTGLERIDINIAPLFE
HADVLMCTRGILRSVVPPATNKPVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLV
DAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGTQIIKTYYVEKGFERIVAGCPVPIVIAGGKKLPEREALEMCW
QAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHNETADRAYELYLSEKQ
>SEQF1516_EDU86634.1 inner membrane ABC transporter permease protein yddQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMLSEETSAVRPQKQTRFNGAKLVWMLKGSPLTVTGAVIIVLMLLMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDE
VGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAM
LAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLINWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLGAQ
QPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLTAVGFNLFGDGIRDLLDPKAGGKQS
>SEQF1516_EDU86635.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLGVLLALSGSVSGASLEVDNGQITNIDTDVAYDAYLVGWYGTGVLNILAGGNASLTTITTSVIGGNEDSEGTVNVLGG
TWRLYDSGNNARPLNVGQSGTGTLNIKQKGHVDGGYLRLGTQAAGVGTVNVEGEDSVLTTELFEIGSYGTGSLNITDKGY
VTSSIVAILGYQANSNGKVVVEKGGEWLIKNNDSSIEFQIGNQGTGEATIREGGLITAENTIIGGNATGVGTLNVQDQDS
VITVRRLYNGYFGNGAVNISNNGLINNKEYSLVGVQDGSHGVVNVTDKGHWNFLGTGEAFRYIYIGDAGDGELNVSREGK
VDSGIITAGMKETGTGNLTVKDKNSVITNLGTNLGYDGHGEMNISNEGLVVSNGGSSLGYGETGVGKVSITTGGIWEVNK
NVYTTIGVAGVGNLNISDGGKFVSQNITFLGDKASGIGTLNLMDATSSFDTVGINVGNFGSGIVNVSNGATLNSTGYGFI
GGNASGKGIVNISTDSLWNLKTSSTNAQLLQVGVLGTGELNITTGGIVKARDTQIALNDKSKGDVRVDGQNSLLETFNMY
VGTSGTGTLTLTNSGTLNVEGGEVYLGVFEPAVGTLNIGAAHGEAAADAGFITNATKVEFGSGEGVFVFNHTNNSDAGYQ
VDMLITGDDKDGKVIHDAGHTVFNAGNTYSGKTLVNDGLLTIASHTADGVTGMGSSEVTIASPGTLDILASTNSAGDYTL
TNALKGDGLMRVQLSSSDKMFGFTHATGTEFAGVAQLKDSTFTLERDNTAALTHAMLQSDIENTTSVNVGEQSIGGLAMN
GGTLIFDTDIPAATLAEGYISVDTLVVGASDYTWKGRNYQVNGTGDVLIGVPKPWNDPMANNPLTTLNLLEHDDNHVGVQ
LVKAQTVIGSGGSLTLRDLQGDEVEADKTLHIAQNGTVVAEGDYGFRLTTAPGDGLYVNYGLKALNIHGGQKLTLAEHGG
AYGATADMSAKIGGEGDLAINTVRQVSLSNGQNDYQGATYVQMGTLRTDADGALGNTRELNISNAAIVDLNGSTQTVETF
TGQMGSTVLFKEGSLTVNKGGISQGELTGGGNLNVTGGTLAVEGLNARYNALTSVSPNAEVSLDNTQGLGRGNIANDGLL
TLKNVTGELRNSISGKGIVSATARTDVELDGDNSRFVGQFNIDTGSALSVNEQKNLGDASVINNGLLTISTERSWAMTHS
ISGSGDLTKLGTGILTLNNDSSAYQGTTDIVGGEIAFGSDSAINTASQHINIHNSGVMSGNVTTAGDVNVMSGGTLRVAK
TTIGESAATWRMAARFK
>SEQF1516_EDU86636.1 phosphodiesterase, YfcE family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLMFASDIHGSLPATERVLELFAQSGAQWLVILGDVLNHGPRNALPEGYAPAKVAERLNEVAHKVIAVRGNCDSEVDQM
LLHFPITAPWQQVLLEKQRLFLTHGHLFGPENLPALNQNDVLVYGHTHLPVAEQRGEIFHFNPGSVSIPKGGNPASYGML
DNDVLSVIALNDQSIIAQVAINP
>SEQF1516_EDU86637.1 penicillin-insensitive murein endopeptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKTAIALLALLASSVSLAATPWQKITQPVPGSAQSIGSFSNGCIVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQR
LSSQVSNLGMGTVLIGDMGMPAGGRFNGGHASHQTGLDVDIFLQLPKTRRTSAQLLRPQALDLVSRDGKHVVSTLWKPEI
FSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPADSLECEDQPLPPPGDGCGAELQ
SWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI
>SEQF1516_EDU86638.1 IS629 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU86639.1 glycerol-3-phosphate transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSK
FIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV
WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELT
AKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFFYEYAGIPGTLLCGWMSDKVFRGN
RGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAA
SAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHQELLQKRNGG
>SEQF1516_EDU86640.1 putative outer membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEYGFAIYNRNNVNVTGVLTPVFFLDRFTAESGSKTYTNKPDGKSLQAVCCLFPWNNVFADRKVPKITINDNTVTWSNLE
QGMGSYIYTFWG
>SEQF1516_EDU86641.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHHDLGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGA
KRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVIGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGA
LAVGAPLGLLIHSHYGFAALALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFVS
LYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIF
PALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG
>SEQF1516_EDU86642.1 Smr domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKVSEVPVKRLIQEQVDASHYFSDEFQPLLNADGPVKYVRPGVD
HFEAKKLRRGDYSPELFLDLHGLTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPK
EYGGDAALLVLIEVEEWLPPELP
>SEQF1516_EDU86643.1 NADH-quinone oxidoreductase, J subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFAFYICGLIAILATLRVITHTNPVHALLYLIISLLAISGVFFSLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSE
IEQERQWLKPQVWIGPAILSAIMLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGR
EERAGEVLSNRKDDSAKRKTEEHA
>SEQF1516_EDU86644.1 hypothetical protein ECH7EC4501_4792 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAILKKYINILRISKVKLKKGFKIARLNIKMKLINYMR
>SEQF1516_EDU86645.1 multidrug resistance protein, SMR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIWLTLVFASLLSVAGQLCQKQATCFVAISKRRKHIVLWLGLALACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLA
AVKLWHEPVSPRHWCGVAFIIGGIVILGSTV
>SEQF1516_EDU86646.1 chaperone protein PapD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNLFCSARTAATTLALLITAASLSVQASVTPDRTRLIFNESDKSISVTLRNNDPKMPYLAQSWMEDGQGNRISSPLTVL
PPVQRIDSMMNGQVKVQGMPDINKLPADRESVFYFNVREIPPKSNKPNTLQIALQTRIKLFWRPKALENVSMKNPWQHKV
TLTLSGQEFTVNNPTPYFVVISNASAQKNGNPAAGFSPMVISPKTSVPLKVKMDSVPVLTYVNDYGARLPLFFRCTGNTC
QVDEEQNSKGQG
>SEQF1516_EDU86647.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEKLWTKDFWAITIISFIIFFVFYVLLTLLPIYISDRLHASPDKAGLLVTLFLIAAIVIRPFAGQWVGKYSNKTILVLS
SLAFLVVTALYPFCHSIESLLFIRVLHGITFGVITTVKGTISARLIPASRRGEGISFFSLAMGLAMVVGPWIGLNMARWE
AFNMAFWLCTGVAAVGIILSLIMTVPPVISHADGSKPKMGFAAMFDRAALPFAMVTFFMTFSYAGVSAFLALYARELNLM
SAASNFLLCYAIFLMICRTFTGNVCDKKGPKYVVYPCLLFFTVGLVVLGYTQGSVMMVVSGALIGIGYGSVTPVFQTQII
SSVEPHKIGVANSLFFNAMDAGLALGACVMGMMVAHTGYRMIYLLGALLVVVAGGVYALQMKGKSGVALVVAKEIH
>SEQF1516_EDU86648.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSTHHYEQLIEIFNSCFADDFNTRLIKGDDEPIYLPADAEVPYNRIVFAHGFYASAIHEISHWCIAGKARREQVDFGYW
YCPDGRDAQTQSQFEDVEVKPQALDWLFCVAAGYPFNVSCDNLEGDFEPDRVVFQRRVHAQVMDYLTNGIPERPARFIKA
LQNYYHTPELTAEQFPWPEALN
>SEQF1516_EDU86649.1 hypothetical protein ECH7EC4501_4852 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDVDILIAYSSKVAPDSLLFTADGRHIDSWGGIKKTLQSL
>SEQF1516_EDU86650.1 ribonucleoside-diphosphate reductase, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYL
AARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNR
VTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINAT
SSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLK
NNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFS
LMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINSLDELEE
LAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAK
EQGACPWFNETTYAKGILPIDTYKKDLDAIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRG
YVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLT
AYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>SEQF1516_EDU86651.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRGANIWFASRRIVGVSALLTSASHPVGGLLLNNQPLREFRICHTP
>SEQF1516_EDU86652.1 alpha-2-macroglobulin family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGTGLANADDSLPSSNYAPPAGGTFFLLADSSFSSSEESKVRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKN
LHRIVVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIIKPSRYVQNNQFSPLKKYPLV
EQFRYPLWQAKPVEPQQGVKLEGASSNFISPQPGNIYIPLGQQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGKELL
VWTAGKKQGEAKPGSEILWTDGLGVMTRGVTDDSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTD
RPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVDVTLDARNGGQGSFRLPENAVAGGYELRLAYR
NQVYSSSFRVANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVKNARVQLSLRAQQLSMVGNDLRYAGRFPVSL
EGSETVSDASGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESS
KQVPVTYEWLRLEDRTSHSGDLPSGGKSFTVNFDKPGNYNLTLRDKDGLILAGLSHAVSGKGSMSHTGTVDIVADKTLYQ
PGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQN
AGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSS
SLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDG
LVGQGRAYLRSEKNLYMKWSMPTVYRVGDKPSAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLAQNIQQSG
LLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMLGGGDNALMLPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGV
INTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVT
QQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTEDFSEEDTRDINDSLILDTPESP
LADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAVNSNQPLAHTVVLLNSGGDATQAAAILSGLTAEQSTIERALAMNW
LAKYMATMPSVVLPAPAGAWAKHKLTGGGEYWRWVGQGVPDILSFGDELSPQNVQVRWREAAKTAQQSNIPVTVERQLYR
LIPGEEEMSFTLQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAGKQQGQLLEKA
RNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAAGSEWTGMQVK
>SEQF1516_EDU86653.1 hypothetical protein ECH7EC4501_4818 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFQPSDMVVYSRNSKAPCQCYSREHEEEINVPDDERR
>SEQF1516_EDU86654.1 hypothetical protein ECH7EC4501_4899 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWLPGIFAYTIPCPMYALQRSENSSENVSQRLKLADVKGLG
>SEQF1516_EDU86655.1 naphthoate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSTDGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNVGVIILTGAGDK
AFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVG
SFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADC
DGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQPDFSKFKRNP
>SEQF1516_EDU86656.1 NADH-quinone oxidoreductase, B subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLNDMVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVAR
FGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPP
RPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPDEI
>SEQF1516_EDU86657.1 fatty oxidation complex, alpha subunit FadJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEMTSAFTLNVRLDNIAIITIDVPGEKMNTLKAEFASQVRAIIKQLRENKELRGVVFVSAKPDNFIAGADINMIGNCKTA
QEAEALARQGQQLMAEIHALPIPVIAAIHGACLGGGLELALACHGRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIG
VSTALEMILTGKQLRAKQALKLGLVDDVVPHSILLEAAVELAKKDRPSSRPLPVRERILAGPLGRAQLFKMVGKKTEHKT
QGNYPATERILEVVETGLAQGTSSGYDAEARAFGELAMTPQSQALRSIFFASTEVKKDPGSDAPPAPLNSVGILGGGLMG
GGIAYVTACKAGIPVRIKDINPQGINHALKYSWDQLEGKVRRRHLKASERDKQLALISGTTDYRGFAHRDLIIEAVFENL
ELKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSPVEKMPLVEIIPHAGTSAQTIATTVKLAKKQ
GKTPIVVRDKAGFYVNRILAPYINEAIRMLTEGERVAHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFS
APANVVSSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGAQGQGRLSAPQVAERCVMLMLNEAVRCVDEQVIR
SVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLATQYGSRFTPCERLVEMGARGESFWKTTATDLQ
>SEQF1516_EDU86658.1 undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLASGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANN
FGVRAGVIFATLLTAALVTWFTLRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKG
KSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLTVLPWGLTIAQREPDFWHYFFWV
EHIQRFALDDAQHRAPFWYYVPVIIAGSLPWLGLLPGALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCF
APLAMLMAHYALLAAKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLWAFFGWYTL
TNVEKTWSFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSRYILTDSVGVAAGLAWSLQRDDIIMYRQTGE
LKYGLNYPDAKGRFVSGDEFANWLNQHRQEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK
>SEQF1516_EDU86659.1 lipoprotein, VacJ family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEE
PAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRD
DGGDMADGLYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA
IQDDLKDIDSE
>SEQF1516_EDU86660.1 3-demethylubiquinone-9 3-O-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLRLSYIAERAGGLFGKKVLDVGCGGGILAESMAREGAT
VTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNPITNTFKLGPGVDVNYMLHTQNK
>SEQF1516_EDU86661.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPYIDITTMRGMMPRVVTSMLPEHSAVLAEDCHFRFGVITPERQISGVEKTFTIKPKTIFHYRDDFWFAWPDVVDVIRSP
IAQDPHGRIYYTDGRFPKVTDATIATKGDGNHPTSSYRLGIPAPTTAPVCTVQQGGDVSDDNPNDDETRFYTETFVSDYG
EEGPPGPASLEVTLRTPGTAVQLTLAPVPLQNASIKRRRIYRSASGGGEADFLLVAELDASVLSYTDKIPAKNLGPSLAT
WDYLPPPENMTGLCLMANGIAAGFAGNEVMFSEAYLPYAWPEVNRHTTAEDIVAICPLGTSLVVATKGEPYLFSGVSPST
ISGSKIPSMQACLSRRSMVAMEGFVLYAGTNGLVSVDANGNVALATEQIVSPEQWQSQFNPASIVAYPWRGEYIACYTKP
DGKQDVFVFSPVNMDIRYLSTPFDCAWVDLAKDMMRVVTGDKMSVLAGGALPSTIRWHSKIFSLPERTSFSCIRVKSPAP
ERVGITIMADDVPVIHFAPGTFKGSVVRLPAATGQNWQVMVSGFGQVERITLSTSMSEMPV
>SEQF1516_EDU86662.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGFAQGLLAGFSTVDQAMTRRKELGLREAQLARQQKNNERDFEFAQSQFEHNKNVDQRNFDYRAKVDDRNYALKEREFN
ANQNYRNASLGMEQQRLQLQKYNQRRLEYNDMIAHSQPLMEALGKAIEAGDQEAATRLFGQLPKGHPLILMSNEGYAAKA
GQAVINLQKIFGDKPDMAIDSLNTPENLDVLSGVFAPELQQRIGMPDSTGDKTIKEARIGSIVPAQQEGYVLIGLDLTYS
DGSTAHKPVTEYGSAHPDDQTVLAIPVDKAIAQVRDRSKFAEISKNYGYFMPKQQGLSLKELQKGASNVAADAIKNGGNA
QAAVDEYYAATGSQPHQQKIQQQKLQQQVINWAGDDPDKLSFARNVAARQPEMLEPQNQKLLENGYANFLRIQKARGEQA
RDESASSASQFIRGLKQNYAQ
>SEQF1516_EDU86663.1 CinA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVGDNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSAL
AAATAKGEGLVLHEAWLKEMERYFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAVQLNRCLMFFTPGVPSEFKVM
VEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPIIELKLTGPASEQQAMEKLWLDVK
RVAGQSVIFEGTEGLPAQISRELQNRQFSLTLSEQFTGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHF
AGLALAVSGFENEHLNFALATPDGTLALRVRFSTTRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEVVESMTLSV
>SEQF1516_EDU86664.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGLIWGLFSVIIASVAQLSLGFAASHLPPMTHLWDFIAALLAFGLDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALL
SMSYVLVWIASMVLPGWEGTFSLKALLGVACIMSGLMLIFLPTTKQRY
>SEQF1516_EDU86665.1 NADH-quinone oxidoreductase, I subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRYRGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKA
ETKDGRWYPEFFRINFSRCIFCGLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDG
KDKGEAENEAKPIDVKSLLP
>SEQF1516_EDU86666.1 C4-dicarboxylate anaerobic carrier protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQGNICAMSAITESKPTRRWAMPDTLVIIFFVAILTSLATWVVPVGMFDSQEVQYQVDGQTKTRKVVDPHSFRLLTNEAG
EPEYHRVQLFTTGDERPGLMNFPFEGLTSGSKYGTAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRHTRGNEILFIPA
LFILFSLGGAVFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQGIAGVPVLSGSGLRI
VVWVIATLIGLIFTMVYASRVKKNPLLSRVHESDRFFREKQADVEQRPFTFGDWLVLIVLTAVMVWVIWGVIVNAWFIPE
IASQFFTMGLVIGIIGVVFRLNGMTVNTMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGDASVLNTILNSIANAIS
GLDNAVAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFGDGFSHIIYPTSASLMATLGVCRV
DFRNWLKVGATLLGLLFIMSSVVVIGAQLMGYH
>SEQF1516_EDU86667.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPNTSIHLSRCNILQNNKLQPTEIYKESQQTAKLEFFCDEFLKISQSRYGLSTSTDSIANLLAFFTKASDAIDSIKTQKI
DVHSYGFVPIRHFVEHVITYKNEFAADYEPYTLTFTRGENNEGILSVESKEGFISQRTINLNEYETAINIINEHVIKENI
HNTVQSPTEKYISKINSSDKPYKTSSKESIKSQLYSDQRNIQTCYYILRKNTEWYKYASSEERYDKFKNSSKEIKNTYKQ
IVQAQKKLNQMKYINKLSGELIDITDKKLAPLINDSFSYTRDFFAYSKQEKNIFTFDNSKFVDPKEKEGLMVQHSNGQLV
ITGKYCPEGVQTAFTQEQYDKLIRYINIFFTFPKLE
>SEQF1516_EDU86668.1 ribosomal large subunit L3 protein glutamine methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKIFVDEAVNELQTIQDMLRWSVSRFSAANIWYGHGTDNPWDEAVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERV
IRRVNERIPVAYLTNKAWFCGHEFYVDERVLVPRSPIGELINNKFAGLISKQPQHILDMCTGSGCIAIACAYAFPEAEVD
AVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSDLPNEYRHEPELGLASGTDGLKL
TRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDVPFTWLEFDNGGDGVFMLTKAQLLAAREHFAIYKD
>SEQF1516_EDU86669.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQGPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGL
SSQYLPPEMTLTPEQRQLAQNWNQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYH
TGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR
>SEQF1516_EDU86670.1 NADH-quinone oxidoreductase, G subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATIHVDGKEYEVNGADNLLEACLSLGLDIPYFCWHPALGSVGACRQCAVKQYQNAEDTRGRLVMSCMTPASDGTFISID
DEEAKQFRESVVEWLMTNHPHDCPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRY
YKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRKWDMQFAPSICQQCSIGCNISPG
ERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLKDRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRA
SVESNFALRELVGEENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALAVRQAVKGK
AREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAPVEDQARLGFAIAHALDNSAPAVDGIEPELQ
SKIDVIVQALAGAKKPLIISGTNAGSLEVIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGR
ADAVVVLENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNEGRAQRFFQVYDPAYYD
SKTVMLESWRWLHSLHSTLLSREVDWTQLDHVIDAVVAKIPELAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANIS
VHEPRQPQDIDTMFTFSMEGNNQPTAHRSQVPFAWAPGWNSPQAWNKFQDEVGGKLRFGDPGVRLFETSENGLDYFTSVP
ARFQPQDGKWRIAPYYHLFGSDELSQRAPVFQCRMPQPYIKLNPADAAKLGVNAGTRVSFSYDGNTVTLPVEIAEGLTAG
QVGLPMGMSGIAPVLAGAHLEDLKEAQQ
>SEQF1516_EDU86671.1 fimbrial usher protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGSYVNAWAENEIQFDSRFLELKGDTKIDLKRFSSQGYVEPGKYNLQVQLNKQPLTEEYDIYWYASENDASKTYACLTP
ELVAQFGLKEDVAKNLQWIHDGKCLKPGQLEGIDIKADLSQSALVISLPQAYLEYTDINWDPPSRWDDGISGLIADYSIT
AQTRHEENGGDDSNEISGNGTVGVNLGAWRLRADWQTDYLHSKSNDDDVINGDDTQKNWEWSRYYAWRALPSLKAKLGLG
EDYLNSDIFDGFNYVGGSISTDDQMLPPNLRGYAPDISGVAHTTAKVTVSQLGRVIYETQVPAGPFRIQDLGDSVSGTLH
IRIEEQNGQVQEYDINTASMPFLTRPGQVRYKLMMGRPQEWGHHVEGGFFSGGEASWGIANGWSLYGGALADEHYQSAAL
GVGRDLSVFGAVAFDITHSHTRLDKETAYGKGSLDGNSFRLSYSKDFDELNSRVTFAGYRFSEENFMTMSEYLDASDSEM
VRTGNDKEMYTATYNQNFRDAGVSVYLNYTRHTYWDRDEQTNYNVMLSHYFNLGSIRNMSISMTGYRYEYDNQADKGVYI
SLSMPWGDSSTISYNGNYGSGSDSSQVGYFSRVDDATHYQLNVGTSDNHSSVDGYYSHDGSLAQVDLSANYHEGQYTSAG
ISLQGGATLTAQGGALHRTQNMGGTRLLIDADGVAGVPVEGNGAAVYTNMFGKAVVADVNNYYRNQAYIDLNNLPENAEA
TQSVVQGTLTEGAIGYRKFSVISGQKAMAVLRLQDGSYPPFGAEVKNDSAQNVGLVDDDGNVYLAGVKPGEHMIVSWGGV
AHCDIHLPDPLPADLFNGLLLPCQQTGAISPSMPHEIKPVIQEQTQQVMPTEAPVSVSAN
>SEQF1516_EDU86672.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic), K-small subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRAR
AKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYK
DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIAT
SSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRNIPGL
ELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
>SEQF1516_EDU86673.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTVVSNYCQLSQTQLSQTFAEKFTVTEELLQSLKKTALSGDEESIELLHNIALGYDEFGKKAEDILYHIVRNPTNDTLS
IIKLIKNACLKLYNLAHTATKHPLKSHDSDNLLFKKLFSPSKLMAIIGEDIPLISEKQSLSKVLLNDKNNELSDGTNFWD
KNRQLTTDEIACYLKKIAANAKNTQVNYPTDFYLPNSNSTYLEVALNDNIKSDPSWPKEVQLFPINTGGHWILVSLQKIV
NEKNNTQQIKCIIFNSLRALGHEKENSLKRIINSFNSFNCDPTRETPNNKNITDHLTEPEIIFLHADLQQYLSQSCGAFV
CMAAQEVIEQMESNSDSAPYTLLKNYADRFKKYSAEEQYEIDFQHRLENRNCYLDKYGDANINHYYRNLEIKNSHPKNRA
SSKRVS
>SEQF1516_EDU86674.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEWQDLHHSELSVSQLYALLQLRCAVFVVEQNCPYQDIDGDDLTGDNRHILGWKNDELVAYARILKSDDDLEPVVIGRV
IVSEALRGEKVGQQLMSKTLDTCTHHWPDKPVYLGAQAHLQNFYQSFGFIPVTEIYEEDGIPHIGMAREVIQA
>SEQF1516_EDU86675.1 NADH-quinone oxidoreductase, L subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALVTAFIGVDFFANGEQAYSQPLWTWMSVGDFNIGFNLVLD
GLSLTMLSVVTGVGFLIHMYASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTDPK
NGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWATLMLLGGAVGKSAQLPLQTWLADA
MAGPTPVSALIHAATMVTAGVYLIARTHGLFLMTPEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLA
LGVQAWDAAIFHLMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLVTAGFFSKDEI
LAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKGVTHSLPLIVLLILSTFVGALIVPPLQGVLPQT
TELAHGSMLTLEITSGVVAVVGILLAAWLWLGKRTLVTSIANSAPGRLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKR
DPLNSMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR
>SEQF1516_EDU86676.1 erythronate-4-phosphate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKILVDENMPYARDLFSRLGEVIAVPGRPIPVAQLADADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQA
GIGFSAAPGCNAIAVVEYVFSSLLMLAERDGFSLHERTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADCGDEGDFRS
LDELVQRADILTFHTPLFKDGPYKTLHLADEKLIRSLKPGAILINACRGAVVDNTALLTCLNEGQKLSVVLDVWEGEPEL
NVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSKFIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVR
RDDAPLRKVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR
>SEQF1516_EDU86677.1 NADH-quinone oxidoreductase, E subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHENQQPQTEAFELSAAEREAIEHEMHHYEDPRAASIEALKIVQKQRGWVPDGAIHAIADVLGIPASDVEGVATFYSQIF
RQPVGRHVIRYCDSVVCHINGYQGIQAALEKKLNIKPGQTTFDGRFTLLPTCCLGNCDKGPNMMIDEDTHANLTPEAIPE
LLERYK
>SEQF1516_EDU86678.1 putative lipopolysaccharide kinase InaA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVSAKHDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAG
VIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYAQHAVTPYSDEVRQAMLKAVALAFKKMHSVNRQHGCCYVRHIY
VKTEGKAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
>SEQF1516_EDU86679.1 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLGGNQLEARFPEHPHPLFVVAESGFGTGLNFLTLWQAF
DQFREAHPQAQLQRLHFISFEKFPLTRADLALAHQHWPELAPWAEQLQAQWPMPLPGCHRLLLDEGRVTLDLWFGDINEL
ISQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRRGLQEAGFTMQKRKGFGRKREML
CGVMEQTLPLPCSTPWFNRTGSSKREVAIIGGGIASALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDE
ALNRFFSNGFTFARRLYDSLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPEELAVAVEANAVEQITGVTTNCSGITY
PQGGWLCPAELTRNVLELAQQQGLQIYYQYQLQDLSRKDDCWLLTFAGDQQATHSVVVLANGHQISRFSQTSSLPVYSVA
GQVSHIPTTPELAKLKQVLCYDGYLTPQNPANQHHCIGASYHRGSEETAYSEDNQQQNRQRLIDCFPHAQWAKTVDVSKK
EARCGVRCATRDHLPMVGNVPDYEATLVEYASLAEQKDKAVSAPVFDDLFMFAALGSRGLCSAPLCAEILAAQMSDEPIP
MDASTLAALNPNRLWVRKLLKGKAVKAG
>SEQF1516_EDU86680.1 aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPAPFGFDAPDEILVDVIRNLPTAQGYCDSKGLYSARKA
IMQHYQARGMRDVTVEDIYIGNGVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDAEHHSIAPLAPDLLTITFNGLSK
TYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRLCANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDI
PGVSCVKPCGALYMFPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRVDDIELSLSKFARFLS
GYHQL
>SEQF1516_EDU86681.1 acetate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSKLVLVLNCGSSSLKFAIIDAVNGEEYLSGLAECFHLPEARIKWKMDGNKQEAALGAGAAHSEALNFIVNTILAQKPE
LSAQLTAIGHRIVHGGEKYTSSVVIDESVIQGIKDAASFAPLHNPAHLIGIEEALKSFPQLKDKNVAVFDTAFHQTMPEE
SYLYALPYNLYKEHGIRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVSAIRNGKCVDTSMGLTPLEGLVM
GTRSGDIDPAIIFHLHDTLGMSVDAINKLLTKKSGLLGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGAYTAL
MDGRLDAVVFTGGIGENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIAQDASRLTA
>SEQF1516_EDU86682.1 histidine ABC transporter, permease protein HisQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYGFSGVILQGALVTLELAISSVVLAVIIGLIGAGGKLSQNRLSGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNTVT
EAMGVGQIDIDPMVAGIITLGFIYGAYFTETFRGAFMAVPKGHIEAARAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQV
ILKSTALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLFLERRYSVGVKRADL
>SEQF1516_EDU86683.1 long-chain fatty acid transport protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSGEGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPD
VNISGTSPSGRSLKADNIAPTAWVPNMHFVAPINDQFGWGASITSNYGLATEFNDTYAGGSVGGTTDLETMNLNLSGAYR
LNNAWSFGLGFNAVYARAKIERFAGDLGQLVAGQIMQSPAGKTPQGQALAATANGIDSNTKIAHLNGNQWGFGWNAGILY
ELDKNNRYALTYRSEVKIDFKGNYSSDLNRVFNNYGLPIPTATGGATQSGYLTLNLPEMWEVSGYNRVDPQWAIHYSLAY
TSWSQFQQLKATSTSGDTLFQKHEGFKDAYRIALGTTYYYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRFWLSAGTTY
AFNKDASVDVGVSYMHGQSVKINEGPYQFESEGKAWLFGTNFNYAF
>SEQF1516_EDU86684.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLTQINSLLAVLDYGGFTEASKRLFMTQSAVSQAIAALEQELGVNILLRDRRKAIQLTTAGHRIVQHLRAINREVNAVK
EIAEQEKQNPQRTLRLGCFPSVCACILPVVIRYFEIHHPNIKIIPFEENSTAIIDSLQNESIDAGFVHFPVSGMYSVPIY
QDKFTVVLPPNHALAKNSTITVEELMGEPLIISKGRYELSIMALFKEKNITPQIKYEFNHPDTAISFIRQGLGIALLPEL
TLKTIADELCSVPLEPTFYRQISLLAKEKPVEGSPLFLLQMCTEQLVVSGKI
>SEQF1516_EDU86685.1 isochorismate synthase, menaquinone-specific [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWLASQQTYPQFYWQQRNGDEEAAVLGAITRFTSLDQAQ
RFLRQHPEHADLRIWGLNAFDPSQGNLLLPRLEWRRCGGKATLRLTLFSESSLQHDAIKAREFIATLVSIKPLPGLHLTT
TREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLNLNCYHFYMAFDGENAFLGSSPE
RLWRRRDKALRTEALAGTVANHPDDKQAQQLGEWLMADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLR
RCIWTSLNKADDVICLHQLQPTAAVAGLPRDLARQFIAHHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKISGNVVRLYA
GAGIVRGSDPEQEWQEIDNKAAGLRTLLQME
>SEQF1516_EDU86686.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKWTIFLTSLILLALSLETPKCYAGDKLMSASFSSTKIYYAMKNVTASGSLYFYVTVVTPGEVSYGQYNSNARKGDTLK
LISWSGSGPAPTLVLTDYRRTDTSNCPGINTRVFVCAYMTFNVTVESDNYGCPWIASFYSVSEAFGFGTYTSPTVHDSIC
PTIPVASFDISWSDNYVSHNKALRLQSDGSTITTTLSTYLMESGKLCDGSIFDSRGAYCRAVSDLLTFTSYGCDNAKVTV
TPSRQPLTDRKLHDIVVQVNTSSREPIDSTCRFQYVLNEL
>SEQF1516_EDU86687.1 phosphate acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPRTGGDAPDQTTTIVRANSSTTTAAEPLKMSYVEGLLS
SNQKDVLMEEIVANYHANTKDAEVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLKERIELTRNSFG
GAKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSSKAKVNNVDPAKLQESSPLPVLGAVPWSFDLIATRAIDMARHLN
ATIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSLLVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCE
RAFATGLPVFMVNTNTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIDSLTATSERSRRLSPPAFRYQLTELA
RKAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPAEINRVAASQGVELGAGIEIVDPEVVRESYVGRLVELRKNKG
MTETVAREQLEDNVVLGTLMLEQDEVDGLVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPD
PTAEQLAEIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGPLQYDAAVMADVAKSKA
PNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQGMRKPVNDLSRGALVDDIVYTIALTAIQSAQQQ
>SEQF1516_EDU86688.1 fimbrial subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLWSFSFMALSNVSFHGYLVQPPNCSISNGQNIELTFRDVNIDDINGSNYEQVVPYTITCDTAVRDPQMEMTLTWSGTQS
DFDDSAVATDLNGLGIHLKQAGSDFKLHTPLVVNETSLPVLTAVPVKKSGVDLPESDFEAWATLQVDYQ
>SEQF1516_EDU86689.1 undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFEIHPVKKVSVVIPVYNEQESLPELIRRTTTACESLGKEYEILLIDDGSSDNSAHILVEASQAENSHIVSILLNRNYGQ
HSAIMAGFSHVTGDLIITLDADLQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
CMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHAEREYGESKYSFMRLINLMYDLVTCLTTTPLRMLSLLG
SIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAVLFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKE
NE
>SEQF1516_EDU86690.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDKILWYMQRVVRNSRNPEFMNEVKDACLKKQAFCFEAPDGFLVLRSVLSADGIPYVLVLLGVCTGSNSVERYLPEVKT
LTHLAGGRWAEFHTARRGFIRLGKRLGFERMPDDEDGFMVFRIAV
>SEQF1516_EDU86691.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METFNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALMAAGMSPANALATNKLQACGGSISATIYFIRRKVVSL
SDQKLNIAMTFVGSMSGALLVQYVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFG
PAAGSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVGQFLGARMGSRLVLSKGQKLIRP
MIVIVSAVMSAKLLYDSHGQEILHWLGMN
>SEQF1516_EDU86692.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGMIGYFAEIDSEKINQLLESTEKPLMDNIHDTLSGLRRLDIDKRWDFLHFGLTGTSAFDPAKNDPLSRAVLGEHSLEDG
IDGFLGLTWNQELAATIDRLESLDRSELRKKFSIKRLNEMEIYPGVTFSEELEGQLFASIMLDMEKLISAYRRMLRQGNH
ALTVIVG
>SEQF1516_EDU86693.1 putative transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNGELIWVLSLLAVAIVLFATGRVRMDAVALFVIVAFALSGTLTVPEVFSGFSDPNVVLIAALFIIGDGLVRTGVATVMG
TWLVKVAGNSEIKMLVLLMLTVAGLGAFMSSTGVVAIFIPVVLSVAMRMQTSPSRLMMPLSFAGLISGMMTLVATPPNLV
VNSELLREGYHGFSFFSVTPIGLVVLVLGILYMLVMRFMLKGDTQTPQREGWTRRTFRDLIREYRLTGRARRLAIRPGSP
MIGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVNGVSEFRARDVLLIDMSAADVDLRQFCSEQLLEPMVLRGEYFSDQ
ALDVGMAEISLIPESELIGKSVREIGFRTRYGLNVVGLKRNGVALEGSLADEPLLLGDIILVVGNWKLIGMLAKQGRDFV
ALNLPEEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPVAAIIACLLMGKFRCIDAESAYKSIHWPSIILIVGMMPFA
VALQKTGGVALAVKGLMDIGGGYGPHMMLGCLFVLSAVIGLFISNTATAVLMAPIALAAAKTMGVSPYPFAMVVAMAASA
AFMTPVSSPVNTLVLGPGNYSFSDFVKLGVPFTIIVMAVCVVMIPMLFPF
>SEQF1516_EDU86694.1 histidine ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLK
VADKNQLRLLRTRLTMVFQHFNLWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQR
VSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHVSTHVIFLHQGKIEEEGAPEQLF
GNPQSPRLQQFLKGSLK
>SEQF1516_EDU86695.1 hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGERIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEI
YMIYLIFDCVSANREVKINEEFQDYAWVKPEDLAHYDLNVATRKTLRLKGLL
>SEQF1516_EDU86696.1 phosphohistidine phosphatase SixA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQVFIMRHGDAALDAASDSVRPLTTNGCDESRLMANWLKGQKVEIERVLVSPFLRAEQTLEEVGDCLNLPSSAEVLPELT
PCGDVGLVSAYLQALTNEGVASVLVISHLPLVGYLVAELCPGETPPMFTTSAIASVTLDESGKGEFNWQMSPCNLKMAKA
I
>SEQF1516_EDU86697.1 mandelate racemase/muconate lactonizing enzyme family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLPKIKQVRAWFTGGATAEKGAGGGDYHDQGANHWIDDHIATPMSKYRDYEQLRQSFGINVLGTLVVEVEAENGQTGFA
VSTAGEMGCFIVEKHLNRFIEGKCVSDIKLIHDQMLNATLYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAV
RDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGEDFWLMLDCWMSQDVNYATKLAHACA
PYNLKWIEECLPPQQYEGYRELKRNAPVGMMVTSGEHHGTLQSFRTLSETGIDIMQPDVGWCGGLTTLVEIAAIAKSRGQ
LVVPHGSSVYSHHAVITFTNTPFSEFLMTSPDCSTMRPQFDPILLNEPVPVNGRIHKSVLDKPGFGVELNRDCNLKRPYS
H
>SEQF1516_EDU86698.1 DNA gyrase, A subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPH
GDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP
TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKV
YIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNL
YSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHA
PTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKE
LLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQ
RRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEF
EEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVEGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTG
VRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITD
AGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
>SEQF1516_EDU86699.1 o-succinylbenzoate-CoA ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIFSDWPWRHWRQVRGEAIALRLNDEQLNWRELCARVDELASGFAVQGVVEDSGVMLRAWNTPQTLLAWLALLQCGARVL
PVNPQLPQPLLEELLPNLTLQFALVPDGENTFPALTSLHIQRVEGAHVATWQPTRLCSMTLTSGSTGLPKAAVHTYQAHL
ASAEGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWRWLYAGARMTVRDKQPLEQMLAGCTHASLVPTQLWRLLVNRSSVSL
KAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFASTVCAKEADGLADVGSPLPGREVKIVNNEVWLRAASMAEGYWRNG
QLVSLVNYEGWYATRDRGEMHNGKLTIVGRLDNLFFSGGEGIQTEEVERVIAAHPAVLQVFIVPVADKEFGHRPVAVMEY
DHESVDLSEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQALKEWVQRQQ
>SEQF1516_EDU86700.1 acetyl-CoA carboxylase, carboxyl transferase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLEVCPKCDHHMRMTARNRLHSLLDEGSLVELGSELEPK
DVLKFRDSKKYKDRLASAQKETGEKDALVVMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFS
ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNIAEPKALIGFAGPRVIEQTVREK
LPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAKLMNLPAPNPEAPREGVVVPPVPDQEPEA
>SEQF1516_EDU86701.1 sensor histidine kinase/response regulator RcsC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQRESDIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENR
LSAENGVLSPRGRETQADVPAFEPLFADSDCSAMSNTWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGL
RDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANRLQALLGVEQTIRMENFFLPGTL
PMGVTILDENGHTLISLTGPESKIKADPRWMQERSWFGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAI
LLNVLAGAALFTLARMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLNMLTHEDRQ
RLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRVKMEESLQEMAQAAEQASQSKSMFLATVSHE
LRTPLYGIIGNLDLLQTKELPKGVDRLVTAMNNSSSLLLKIISDILDFSKIESEQLMIEPREFSPREVMNHITANYLPLV
VRKQLGLYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVRADGDYLSIRVRDTGVGIPAKEVVRLFDPF
FQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGSQFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQ
FLETSLQRSGIVVTTYEGQEPTPEDVLITDEVVSKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARIYL
IEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTANDGVDALNVLSKNHIDIVLSDVNMPN
MDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRCLESGMDSCLSKPVTLDVIKQTLTVYAERVRKSRES
>SEQF1516_EDU86702.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASFSQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKV
QQGRLVVNGASMPQRIESDGSFARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHV
VTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYYGGRSETELTTAQLTLITDEGSVNEKQETF
IVPMRNAGELTLVKSFDW
>SEQF1516_EDU86703.1 hydrolase, alpha/beta fold family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILHAQAKHGKPGLPWLVFLHGFSGDCLEWQEVGEAFADYSRLYVDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILSF
WLVGYSLGGRVAMMAACQGLAGLCGVVVEGGHPGLQNAEQRAERQRSDRQWAQRFRSEPLTAVFADWYQQPVFASLNDDQ
RRELVVLRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAAELAADCHVIPRAGHNAHRENPA
GVIASLAQILRF
>SEQF1516_EDU86704.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFANRAEAEQTLAALTEKARSVESEPCKISPTFTEESDGVRLDIDFTF
ACEAEMLIFQLGLR
>SEQF1516_EDU86705.1 putative minor fimbrial subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKGAYSAWAWLLLCSIVSTPVMAGSKSVAMVLRVLVDAPPPCTVTGASVEFGNVFISKIDGVSYKRPIDYSLVCNNLAMD
DLRLNMQATTTVINGETVIDTGIAGFGIRIQKVSDHSILDLTPGAWLPFNFSSGALALEAVPVVQSGVSLTAAEFSASAT
IVVDYQ
>SEQF1516_EDU86706.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU86707.1 histidine ABC transporter, periplasmic histidine-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLVLSLSLVLAFSSATAAFAAIPQNIRIGTDPTYAPFESKNSQGELVGFDIDLAKELCKRINTQCTFVENPLDALIPS
LKAKKIDAIMSSLSITEKRQQEIAFTDKLYAADSRLVVAKNSDIQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIV
SYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPSVKDEKLFGVGTGMGLRKEDNELREALNKAFAEMR
ADGTYEKLAKKYFDFDVYGG
>SEQF1516_EDU86708.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTESTTSSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQTLRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCV
IEHQSSAEKNMAFRLMRYATAAMQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDIT
IVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQCGDTSRFTRFIQEIAERSPLQK
ERLMTIAERLRQEGHQIGWQEGKLEGLQEGMHEQAIKIALRMLEQGFDRDLVLAATQLSEADLAANNH
>SEQF1516_EDU86709.1 tRNA pseudouridine synthase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALSQVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKD
AAWTLGVNANLPGDIAVRWVKAVPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGEND
FTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHNQPESWIAELLAAKDRTLAAATA
KAEGLYLVAVDYPDRYDLPKPPMGPLFLAD
>SEQF1516_EDU86710.1 glycerophosphoryl diester phosphodiesterase GlpQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLPEHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDH
YLDRVTDVADRFPDRARKDGRYYAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNH
STGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRIKNELEPKMGMDLNLVQLIAYTD
WNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADGIGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKL
PEYTTDVNQLYDALYNKAGVNGLFTDFPDKAVKFLNKE
>SEQF1516_EDU86711.1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTLSLETDFSLREVQALADVTHDARDIAASISSGSFQTL
GMVILPCSIKTLSGIVHSYTDGLLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
DVINQTVNRVLDQFAITLPEDLFARWQGA
>SEQF1516_EDU86712.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQDNQMARYGVNRPDNPDSNTLGLRNALAIAGAKNGIREAEQDRQMNILTGASAPARQKLSVGGQLVAA
>SEQF1516_EDU86713.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNDKIDQHSDEIEVESEEKERGKKIEIDEDRLPSRAMAIHEHIRQDGEKELERDAMALLWSAIAAGLSMGASLLAKGIF
HVELEGVPGSFLLENLGYTFGFIIVIMARQQLFTENTVTAVLPVMQKPTMSNVGLLMRLWGVVLLGNILGTGIAAWAFEY
MPIFNEETRDAFVKIGMDVMKNTPSEMFANAIISGWLIATMVWMFPAAGAAKIVVIILMTWLIALGDTTHIVVGSVEILY
LVFNGTLHWSDFIWPFALPTLAGNICGGTFIFALMSHAQIRNDMSNKRKAEARQKAERAENIKKNDKNPA
>SEQF1516_EDU86714.1 NAD-binding domain 4 protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIVITGGTGLIGRHLIPRLLELGHQITVMTRNPQKASSVLGPRVTLWQGLADQSNLNGIDAVINLAGEPIADKRWTHEQ
KERLCQSRWNITQKLVDLINASDTPPSVLISGSATGYYGDLGEVVVTEEEPPHNKFTHKLCARWEEIACRAQSDKTRVCL
LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRGPFNMVSPYPIRNEQFAHALGHA
LHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRLEEAGFAFRWYDLEEALADVVR
>SEQF1516_EDU86715.1 polymyxin B resistance protein pmrD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEWLVKKSCCNKQDNRHVLMLCDAGGAIKMIAEVKSDFAVKVGDLLSPLQNALYCINREKLHTVKVLSASCYSPDEWERQ
CKVAGKTQ
>SEQF1516_EDU86716.1 outer membrane protein, YfaZ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIALAGLAGMLLVSASVNAMSISGQAGKEYTNIGVGFGTESTGLALSGNWTHNDDDGDVAGVGLGLNLPLGPLMATVG
GKGVYTNPNYGDEGYAAAVGGGLQWKIGNSFRLFGEYYYSPDSLSSGIKSYEEANAGARYTIMRPVSIEAGYRYLNLSGK
DGNRDNAVADGPYVGVNASF
>SEQF1516_EDU86717.1 div protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIQPISGPPPGQPPGQGDNLPSGAGNQPLSSQQRTSLESLMTKVTSLTQQQRAELWAGIRHDIGLSGDSPLLSRHCPAAE
HNLAQRLLAAQKSHSARQLLAQLGEYLRLGNNRQAVTDYIRHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREAT
DRPLLPAEHNALKQLVTKLAAATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWLQARQTLSQQNTPTLESLQMTLK
QPLDASELAALSAYIQQKYGLSAQSSLSSAQAEDILNQLYQRRVKGIDPRDMQPLLNPFPPMMDTLQNMATRPALWILLV
AIILMLVWLVR
>SEQF1516_EDU86718.1 NADH-quinone oxidoreductase, C/D subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATRTGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGM
DERLRTHREGLPAADFSVFYHLISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMM
PQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFLNLGPNHPSAHGAFRIVLQLDGE
EIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIEYLGGCVNEMPYVLAVEKLAGITVPARVNVIRVMLSELFRINSHL
LYISTFIQDVGAMTPVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLASYEKAALQ
NTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENFDFEIPVGGGVSDCYTRVMLKVEELRQSLRI
LEQCLNNMPEGPFKADHPLTTPPPKERTLQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTR
IRTPSYAHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR
>SEQF1516_EDU86719.1 anaerobic glycerol-3-phosphate dehydrogenase, subunit B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFDTIIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGSLDLLSHLPDGQAVTDIHSGLESLRQQAPAHPYSLLG
PQRVLDLACQAQALIAESGAQLQGSVELPHQRITPLGTLRSTWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLR
ELDLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMILMPACFGLADDKLWRWLNEKLP
CSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPGDEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLV
AERNGIREPILGLDVLQTATRGEWYKGDFFAPQPWQQFGVTTDQTLRPSQAGQTIENLFTIGSVLGGFDPIAQGCGGGVC
AVSALHAAQQIAQRAGGQQ
>SEQF1516_EDU86720.1 NADH-quinone oxidoreductase, K subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASALAFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALL
LQLHRRRQNLNIDSVSEMRG
>SEQF1516_EDU86721.1 ribonucleoside-diphosphate reductase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRKMPYPALNSQQDTLMAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDY
QALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVT
NEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERE
LMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKD
ILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDSEVDTDDLSNFQL
>SEQF1516_EDU86722.1 sporulation and cell division repeat protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASKFQNRLVGTIVLVALGVIVLPGLLDGQKKHYQDEFAAIPLVPKAGDRDEPDMMPAATQALPTQPPEGAAEEVRAGDA
AAPSLDPATIAANNTEFEPEPAPVVPPKPKPVEPPKPKVEAPPAPKPEPKPVVEEKAAPTGKAYVVQLGALKNADKVNEI
VGKLRGAGYRVYTSPSTPVQGKITRILVGPDASKDKLKGSLGELKQLSGLSGVVMGYTPN
>SEQF1516_EDU86723.1 chorismate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHDLDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTS
IGLLIENTDQRSQDYSAIKDVFRPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
GDIPLEIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGLGEPVFDRLDADIAHALMSINAV
KGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGILGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRH
DPCVGIRAVPIAEAMLAIVLMDHLLRQRAQNADVKTDIPRW
>SEQF1516_EDU86724.1 hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQRRLASTEWVDIVNEENEVIAQASREQMRAQCLRHRATYIVVHDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQ
LLESARREAEEELGIAGVPFAEHGQFYFEDKNCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLKA
LALWMKRNAKNEAVETETAE
>SEQF1516_EDU86725.1 YfbU domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQMRELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQ
DQQSIDERRVTFLGFDAATEARYLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQ
IINA
>SEQF1516_EDU86726.1 NADH-quinone oxidoreductase, A subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARARSKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDV
EALYLFAWSTSIRESGWVGFVEAAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR
>SEQF1516_EDU86727.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFVIEGLLAVGAGVFTFFWLDDTPEQARFLSKLEKTLLINQLASEEQQKVTSRLSDALRNGRVWQLAIIYLTIQVAVYGL
IFFLPTQVAALLGTKVGFTASVVTAIPWVAALFGTWLIPRYSDKTGERRNVAALTLLAAGIGIGLSGLLSPVLAIVALCV
AAIGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLLGAVGGFIAPILRVKAETLFASDAAGLLTLAAVAVIGSLIIFTLRV
NRTVAQTDVAHH
>SEQF1516_EDU86728.1 capsular synthesis regulator component B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPS
LSIIVLTMNNNPAILSAVLDLDIEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD
>SEQF1516_EDU86729.1 o-succinylbenzoic acid (OSB) synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGEISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQM
PSVAFGVSCALAELADTLPQAANYRTAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
DANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLREPDFAFVAEEGVRAVVIKPTLTG
SLEKVREQVQAAHALGLTAVISSSIESSLGLTQLARIAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL
>SEQF1516_EDU86730.1 anaerobic glycerol-3-phosphate dehydrogenase subunit, A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKR
IARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLD
AKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRI
NQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVAS
DDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEPAEVTLRKV
ISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAA
GLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
>SEQF1516_EDU86731.1 putative inner membrane protein YfbV [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMTRYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFAL
SLPMQGLWWLGKRSVTPLPPAILNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL
>SEQF1516_EDU86732.1 polysaccharide deacetylase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDNMGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTA
WPGKEIGHANADIIREAAKYHEVGLHAWDHHAWQARSGNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQQVIE
AKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLLNRILRDKGTPVYTIHAEVEGCA
YQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVVRGNIAGREGWLGCQQIAGSR
>SEQF1516_EDU86733.1 NADH-quinone oxidoreductase, M subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALITMGLTLALSLQLWLQGGYSLTQSAGIPQWQSEFDMPWIPRFGISIH
LAIDGLSLLMVVLTGLLGVLAVLCSWKEIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHK
ASDGKTRITAATKFFIYTQASGLVMLIAILALVFVHYNATGVWTFNYEELLNTPMSSGVEYLLMLGFFIAFAVKMPVVPL
HGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSLPLFPNASAEFAPIAMWLGVIGIFYGAWMAFAQTDIKRLIAYTSV
SHMGFVLIAIYTGSQLAYQGAVIQMIAHGLSAAGLFILCGQLYERIHTRDMRMMGGLWSKMKWLPALSLFFAVATLGMPG
TGNFVGEFMILFGSFQVVPVITVISTFGLVFASVYSLAMLHRAYFGKAKSQIASQELPGMSLRELFMILLLVVLLVLLGF
YPQPILDTSHSAIGNIQQWFVNSVTTTRP
>SEQF1516_EDU86734.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQKSLITVTICMTVIFTIWMLHGSLCEFRLNLWGAEFAAFLQCKQ
>SEQF1516_EDU86735.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELESGDDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTD
MWENLFQQASQQ
>SEQF1516_EDU86736.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGYGLLDIANQSRREALQGISDADRRREEIEAANKQMAAQQKAQNKQNIGTGIGTGAAIGASVGGPVGAVAGAVIGGIAG
SLF
>SEQF1516_EDU86737.1 sugar-phosphatase, YfbT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRCKGFLFDLDGTLVDSLPAVERAWSNWARRHGLAPEEVLAFIHGKQAITSLRHFMAGKSEADIAAEFTRLEQIEATETE
GITALPGAIALLNHLNKAGIPWAIVTSGSMPVARARHKIAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
VEDAPAGVLSGLAAGCHVIAVNAPADTPRLNEVDLVLHSLEQITVTKQPNGDVIIQ
>SEQF1516_EDU86738.1 5'-nucleotidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHALAAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPT
PVKYFNSQIAQEYKAIEKIAQQKLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAK
TRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL
>SEQF1516_EDU86739.1 histidine ABC transporter, permease protein HisM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEILHEYWKPLLWTDGYRFTGVAITLWLLILSVVIGGVLALFLAIGRVSSNKYIQFPIWLFTYIFRGTPLYVQLLVFYS
GMYTLEIVKGTEFLNAFFRSGLNCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSTFKMYRCIILPSALRIAL
PAYSNEVILMLHSTALAFTATVPDLLKIARDINAATYQPFTAFGIAAVLYLIISYVLISLFRRAEKRWLQHVKPSSTH
>SEQF1516_EDU86740.1 membrane protein, DedA family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLVVTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLI
AAIVGDAVNYTIGRLFGEKLFSNPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
VIGALLWVLLFTYAGYFFGTIPMVQDNLKLLIVGIIVVSILPGVIEIIRHKRAAARAAK
>SEQF1516_EDU86741.1 NADH-quinone oxidoreductase, F subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIIRTPETHPLTWRLRDDKQPVWLDEYRSKNGYEGARKALTGLSPDEIVNQVKDAGLKGRGGAGFSTGLKWSLMPKDE
SMNIRYLLCNADEMEPGTYKDRLLMEQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVNLRRAIAEATEAGLLGKNI
MGTGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPATSGVWGKPTCVNNVETLCNVPAILANGVEWYQNIS
KSKDAGTKLMGFSGRVKNPGLWELPFGTTAREILEDYAGGMRDGLKFKAWQPGGAGTDFLTEAHLDLPMEFESIGKAGSR
LGTALAMAVDHEINMVSLVRNLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLGPGKTFCAH
APGAVEPLQSAIKYFREEFEAGIKQPFSNTHLINGIQPNLLKERW
>SEQF1516_EDU86742.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQYAGSGPEKTLSPLVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIEGSIRRIVY
EHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPLLFAATSDSQLSKTEISSIKINSETIPVYQL
RYNGNNALMFATYQDKMLVFSSTDMLFKDDQQDTEATAIASDLLSGKKRWQASFGLEERAAEKTPVRQRIVASARLLGFG
YQRLMPSFAGVRFEMGNDGWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAEEMLSHISQENDKLNGA
LDGAAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNIGAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPK
AQAAQPDQLMSDYFFRVSLAMQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGVAKLLRNETLTSL
PKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPIIWQPL
>SEQF1516_EDU86743.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTISTTSTPHDAVFKSFLRHPDTARDFIDIHLPAPLRKLCDLTTLKLEPNSFIDEDLRQYYSDLLWSVKTQEGVGYLYVV
IEHQSKPEELMAFRMMRYSIAAMQNHLDVGYKELPLVIPMLFYHGCRSPYPYSLCWLDEFAEPAIARKIYSSAFPLVDIT
VVPDDEIMQHRKMALLELIQKHIRQRDLLGLVDQIVSLLVTGNTNDRQLKALFNYVLQTGDAQRFRAFIGEITERAPQEK
EKLMTIADRLREEGAMQGKHEEALRIAQEMLEKGFDHEVILTLTRLSPDDLIAQSH
>SEQF1516_EDU86744.1 putative outer membrane autotransporter adhesin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIASLFSANGVAAAIDLCQGYDIKASCHASRQSLSGITQVWSIADGQWLVFSDMTNNASGGAVFLQQGAEFTLSPENETG
MTLFANNTVSGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAIDLRVTNAVFRNNIANDGKGGAIY
TINNDIYLSDDVFNNNQAYTSTSYSDGDGGAIDVTDNNSDSKHPSGYTIINNTAFTNNTAEGYGGAIYTNSATAPYLIDI
SVDDSYSQNGGVLVDENNSAAGYGDGPSSAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSGDL
VLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDKYQNQAELNVGSTQQTFAHSLTGFQNGT
LNIDAGGNVTVNQGSFAGTIEGAGQLTIAQNGSYVLAGAQSMALTGDIVVDAGAVLSLEGDAADLAALQDDPQSIVLNGG
MLDLSDFSTWQSGTSYKDGLEVSGSSGTVIGSQDVVDLAGGNDMHIGGDGKDGVYVVIDAGDGQVSLANDNQYLGTTQIA
SGTLMVSDNSQLGYTHYNRQVIFTDKPQESVMEITANVDTRSTTTEHGRDIEMRADGEVAVDAGVDTQWGALMADSSGQH
QDEGSTLTKTGAGTLELTASGTTQSAVRVEEGTLQGDVADIFPYASSLWVGDGATFVTGADQDIQSIDATSSGTIDISDG
TVLRLTGQDTSVALNASLFNCDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNTSGAVSLQNGVAGDTLTVN
GDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVNSITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVN
MGAYDYTLVEDNNDWYLRSQEVTPPSPPDPDPTPDPDPTQDPDPTPDPEPTPAYQPVLNAKVGGYLNNLRAANQAFMMER
RDHAGGDGQTLNLRVIGGDYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGTDGEWMLGIVGGYSDNQGDSRSSMTGTRADN
QNHGYAVGLTSSWFQHGKQKQGAWLDNWLQYAWFSNDVSEHEDGVDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQ
GVQQDDFTAANRARVSQSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDASTISDDAVKQRGEIKVGVTG
NISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW
>SEQF1516_EDU86745.1 hypothetical protein ECH7EC4501_4774 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRSDASRCYSGNDNAVKKGEQYAPPNRKKIAIINEVI
>SEQF1516_EDU86746.1 outer membrane protein Lom [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSIATLVVCAISGIACVNLSAHAAEGEHTISLGYAHFQFPGLKDFVKDATAHNRETFSHFVNRNYFSSLGEYTDGRVSG
YEGKDKNPQGINIRYRYEITDDFGVITSFTWTRSLTNSQTFIDVQSADHTRKIKNPAASARTDIRANYWSLLAGPSWRVN
QYMSLYAMAGMGVAKVSADLKIKDNINSSGGFSESNSTKKTSLAWAAGAQFNLNESVTLDVAYEGSGSGDWRTSGVTAGI
GLKF
>SEQF1516_EDU86747.1 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEGKAMSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNHALEQAFCQLTGNQHAIAVSSATAGMHITLMALEIGKGD
EVITPSLTWVSTLNMISLQGATPVMVDVDRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADINAIRAIGERYGIAVIED
AAHAVGTYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENIARQLRMLKFHGLGVDAYDRQTWGRAPQAEVLTPGY
KYNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPFQPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALK
ERGIGTGLHFRAAHTQKYYRERFPSLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ
>SEQF1516_EDU86748.1 phosphoglycerate mutase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLGRLAQQHPVVVLFRHAERCDRSTNQCLSDKTGIT
VKGTQDARELGNAFSADIPDFDLYSSNTVRTIQSATWFSAGKKLTVDKRLLQCGNEIYSAIKDLQSKAPDKNIVIFTHNH
CLTYIAKDKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH
>SEQF1516_EDU86749.1 2Fe-2S iron-sulfur cluster-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDI
EIEL
>SEQF1516_EDU86750.1 glutathione S-transferase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKPAITLWSDAHFFSPYVLSAWVALQEKGLLFHIKTIDLDSGEHLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLE
DRFAPPTWERIYPLDLENRARARQIQAWLRSDLMPIREERPTDVVFAGAKKAPLTAEGKASAEKLFAMAEHLLVLGQPNL
FGEWCIADTDLALMINRLVLHGDEVPECLVDYATFQWQRASVQRFIALSAKQSG
>SEQF1516_EDU86751.1 acetyl-CoA C-acyltransferase FadI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMVVGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREI
VLGTGMNVHTDAYSVSRACATSFQAVANVVESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLF
SRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWSDGKLKEEVMTAFIPPYKQLLAE
DNNIRGNSSLADFAKLRPAFDRKHGTVTAANSTPLTDGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPA
WSTPLALERAGLTMADLTLIDMHEAFAAQTLANIQLLGSERFAREALGRAHATGEVDDSKFNVLGGSIAYGHPFAATGAR
MITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE
>SEQF1516_EDU86752.1 fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKFVKTAIAATMVMGAFASTSTIAAGNNGTARFYGTIEDSPCSIVPDDHKLEVDMGDIGSGILKNNGTSTPKAFQIHLQ
DCVFDTQTTMTTTFTGNASSTNSGNYYTIYNTDTGAAFNNVSLAIGDAQGTSYKSGAGIEQKIVNDTATNKGKAKQTLDF
KAWLVGAADAPDLGNFEANTTFQITYL
>SEQF1516_EDU86753.1 transcriptional regulator LrhA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQQMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARK
ILRFNDEACSSLMFSNLQGVLTIGASDESADTILPFLLNRVSSVYPKLALDVRVKRNAYMAEMLESQEVDLMVTTHRPSA
FKALNLRTSPTHWYCAAEYVLQKGEPIPLVLLDDPSPFRDMVLATLNKADIPWRLAYVASTLPAVRAAVKAGLGVTARPV
EMMSPDLRVLSGVDGLPPLPDTEYLLCYDPSSNNELAQVIYQAMESYHNPWQYSPISAPEGDDSLLIERDIE
>SEQF1516_EDU86754.1 UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGSVARLAAERGIPVYAPDNVNHPLWVERIAQLSPEVIF
SFYYRHLICDEILQLAPAGAFNLHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRVAIAPDDIAIT
LHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLHNMVRAVADPWPGAFSYVGNQKF
TVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEIVTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACTARRRTRVLI
LGVNGFIGNHLTERLLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAIATPIEYTR
NPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSNLIVGPVNKPRWIYSVSKQLLDRVIWAYGEK
EGLQFTLFRPFNWMGPRLDNLNAARIGSSRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDG
EIINIGNPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIRNAHHCLDWEPKIDMQE
TIDETLDFFLRTVDLTDKPS
>SEQF1516_EDU86755.1 3-oxoacyl-[acyl-carrier-protein] synthase 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSME
QAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSIS
SACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKASRTYDAHRDGFVIAGGGGMVVV
EELEHALARGAHIYAEIVGYGATSDGADMVAPSGEGAVRCMQMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDK
SPAISATKAMTGHSLGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATLV
MRKLKD
>SEQF1516_EDU86756.1 amidophosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFRLRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGS
SSASEAQPFYVNSPYGITLAHNGNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAAT
NRLIRGAYACVAMIIGHGMVAFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLGFDFLRDVAPGEAIYITEEGQLF
TRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSARVNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKP
YRQGFVKNRYVGRTFIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVYLASAAPEI
RFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIEAVRAENPDIQQFECSVFNGVYVTKDVDQGYLDFLD
TLRNDDAKAVQRQNEVENLEMHNEG
>SEQF1516_EDU86757.1 NADH-quinone oxidoreductase, N subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIGLNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLV
LLASLATCTFAYPWLEGYNDNKDEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYT
ILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKLSLVPFHLWTPDVYQGAPAPVST
FLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAIIAFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGE
MSMEAVGVYLAGYLFSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGFIGKFYVLA
VGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQYSAGGIVVLISALLVLVLGVWPQPLISIVRL
AMPLM
>SEQF1516_EDU86758.1 NADH-quinone oxidoreductase, H subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQNRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDR
VIFTLAPMIAFTSLLLAFAIVPVSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFL
GLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAEQELADGYHIEYSGMKFGLFFVG
EYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTAFFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVI
LWQAQ
>SEQF1516_EDU86759.1 CvpA protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVWIDYAIIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHYYTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIV
NFVIGLLVEKTGLSGTDRVLGVCFGALRGVLIVAAILFFLDSFTGVSKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP
RA
>SEQF1516_EDU86760.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGGSKGGGDTKVKPTAAQIAQEEVAWKGWQDYKNILRPAEDNFMEKVDDLNSEQQYDNIAGTTNLGYQKQFGEARKELAG
NLAQSGVDPSSGRFNAVMNANQSDQVTGQIDTTTRGQVSQADKYVAGLQDVAALGSGQKADALQSFNSLADSSLAKAKSD
AQAAFTKQQGRASLVGAGLGAAGAYAMHKAGGSGGSGGAKTPGTGANAIQHQAQNWRL
>SEQF1516_EDU86761.1 glutathione S-transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIDLYFAPTPNGHKITLFLEEAGLDYRLIKVDLGKGGQFRPEFLLISPNNKIPAIVDHSPADGGEPLSLFESGAILLYLA
EKTGLFLSHETRERAATLQWLFWQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
IADIACWPWVNAWTRQRIDLAMYPAVKNWHERIRSRPATGQALLKAQLGDERSDS
>SEQF1516_EDU86762.1 transcriptional regulator, IclR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLESSKVPALTRAIDILNLIARIGPCNAATIIDTLGIPKSTAYLLLNELRRQRFLSLDHQENFCLWTKLVELSGHALSKM
DLRELARPRLTQLMDTTGLLCHLGIIDNGSAYYILKVESSATISVRSHEGKSLSLYRSGIGKCLLAWQPATVQQSIIEGL
VWEQATPTTITHPQQLHEELARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAISVVGTRLQINEEYRDYLAGKAIA
CARDISRLLGWKSPFDLQAS
>SEQF1516_EDU86763.1 tetrahydrofolate synthase/dihydrofolate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGVLKPAPFVFTVAGTNGKGTTCRTLESILMAAGYKVGV
YSSPHLVCYTERVRVQGQELPESAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVD
ADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGALLQRRGVEWNYSVTDHDWAFSD
AHGTLENLPLPLVPQPNAATALAALRASGLEVSENAIRDGIASAILPGRFQIVSESPRVIFDVAHNPHAAEYLTGRMKTL
PKNGRVLAVIGMLHDKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADAKAEDTVLV
CGSFHTVAHVMEVIDARRSGGK
>SEQF1516_EDU86764.1 aspartate-semialdehyde dehydrogenase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEGWNIAVLGTTGAVGEALLETLAERQFPVGEIYALARNESAGEQLRFGGKTITVQDAAEFDWTQAQLAFFVAGKEATA
AWVEEATNSGCLVIDSSGLFALEPDVPLVVPEVNPFVLTDYRNRNVIAVPDSLTSQLLAALKPLIDQGGLSRISVTSLIS
ASAQGKKAVDALAGQSAKLLNGIPIDEEDFFGRQLAFNMLPLLPDSEGSVREERRIVDEVRKILQDEGLMISASVVQAPV
FYGHAQMVNFEALRPLAAEEARDAFVQGEDIVLSEENEFPTQVGDASGTPHLSVGCVRNDYGMPEQVQFWSVADNVRFGG
ALMAVKIAEKLVQEYLY
>SEQF1516_EDU86765.1 hypothetical protein ECH7EC4501_4869 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLLVAKVVLNEDKKRQLIALNIVRKEMNKYQKSLNMPV
>SEQF1516_EDU86766.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYGLSIMKPDGSVWISPGFTPQCLINKGTIPATEKSFFKTSIPSGKSCFFFIRTEKKADVMYTHEQIDGYHALRLHVIVR
GTNPGVTTVYAFANMVTPPSEYGIAMYNPDGEMIYHGEMMLLDAKLIPVDIKFEKDLGYPCAIMPALVGYYNWKRTPYDR
PIYTTSTGATGNKIYSCEHYSGGATWDIRKPYIDKVLVINTSVYD
>SEQF1516_EDU86767.1 ribonuclease Z [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRDELMELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQHQLLHTAFNPGKLDKIFISHLHGDHLFGLP
GLLCSRSMSGIIQPLTIYGPQGIREFVETALRISGSWTDYPLEIVEIGAGEILDDGLRKVTAYPMEHPLECYGYRIEEHD
KPGALNAQALKAAGVPPSPLFQELKAGKTIMLEDGRQINGADYLAAPVPGKALAIFGDTGPCDAALDLAKGVDVMVHEAT
LDITMEAKANSRGHSSTRQAATLAREAGVGKLIITHVSSRYDDKGCQHLLRECRSIFPATELANDFTVFNV
>SEQF1516_EDU86768.1 fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNNRAWALISGLILFSGTAPAADNLHFTGNLLGKSCTPVINGNLLAEIHFPTIAASDLMQRGQSDRVPLVFQLKDCKST
TAFNVKVTLMGTEDTDLPGFLSIDSSSSATGVGIGIETAGGAAVPINSTTGASFPLNQGNNSVNFNAWLQTVNGRNVTSG
DFTATMTVTFEYF
>SEQF1516_EDU86769.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNQFGDTRIDDDLTLLSETLEEVLRSSGDPADQKYVELKARAEKALDDVKKRVSQASDSYYYRAKQAVYRADDYVHEKP
WQGIGVGAAVGLVLGLLLARR
>SEQF1516_EDU86770.1 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAENSAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSG
TAVANLYPALIEAGLTGEKLILLTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLH
AGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWRQKRGVVVAGRMSAEEGKKVALW
AQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSELQQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAH
HRGRRLIANIADWLELHPAEKRQPWCVEIPRLAEQAMQAVIACRDAFGEAQLAHRISDYLPEQGQLFVGNSLVVRLIDAL
SQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLNALALLRQVSAPLVLIVVNNNGGQIFSLLPT
PKSERERFYLMPQNVHFEHAAAMFELKYHRPQNWQELETVLADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL
>SEQF1516_EDU86771.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTALLDAVVKKNRVRLIPFMLALYVLAFLDRSNIGFAKQTYQIDTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKLGA
RTWIGTTTLLWGFLSAAMAWADTEAKFLIVRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
GALLEMHGFMGHPEPPRVSWRVFYL
>SEQF1516_EDU86772.1 lysine-arginine-ornithine-binding periplasmic protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKSILALSLLVGISAAASSYAALPETVRIGTDTTYAPFSSKDAKGDFVGFDIDLGNEMCKRMQVKCTWVASDFDALIPS
LKAKKIDAIISSLSITDKRQQEIAFSDKLYAADSRLIAAKGSPIQPTLDSLKGKHVGVLQGSTQEAYANETWRSKGVDVV
AYANQDLVYSDLAAGRLDAALQDEVAASEGFLKQPAGKDFAFAGSSVKDKKYFGDGTGVGLRKDDAELTAAFNKALGELR
QDGTYDKMAKKYFDFNVYGD
>SEQF1516_EDU86773.1 tRNA-specific adenosine deaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEVEFSHEYWMRHAMTLAKRAWDEREVPVGAVLVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATL
YVTLEPCVMCAGAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVEITEGILADECAALLSDFFRMRRQEIKAQK
KAQSSTD
>SEQF1516_EDU86774.1 surface antigen family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFKKCLLPVAMLASFTLAGCQSNADDHAADVYQTDQLNTKQETKTVNIISILPAKVAVDNSQNKRNAQAFGALIGAVAG
GVIGHNVGSGSNSGTTAGAVGGGAVGAAAGSMVNDKTLVEGVSLTYKEGTKVYTSTQVGKECQFTTGLAVVITTTYNETR
IQPNTKCPEKS
>SEQF1516_EDU86775.1 exodeoxyribonuclease VII, large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPASGHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQV
LVRANITLYEPRGDYQIIVESMQPAGEGLLQQKYEQLKAKLQAEGLFDLQYKKPLPSPAHCVGVITSKTGAALHDILHVL
KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQCNECDVLIVGRGGGSLEDLWSFNDERVARAIFASRIPVVSAVGHET
DVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQSTRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLE
RLQKRMSFALENQLKRAGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTHLEAVSPLS
TLARGYSVTTATDGKVLKKVKQVKAGEMLTTRLEDGWVESEVKNIQPVKKSRKKVH
>SEQF1516_EDU86776.1 iron-sulfur cluster-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACGACACACPTNALTIQTDDQQNSRTWQLYLGRCIYCGR
CEEVCPTRAIQLTNNFELTVTNKADLYTRATFHLQRCSRCERPFAPQKTVALAAELLAQQQNAPQNREMLRAQASVCPEC
KQRATLINDDTDVPLVAKEQL
>SEQF1516_EDU86777.1 ethanolamine utilization protein EutS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDAGAIGIMTLTPGETAMIAGDLALKAADVHIGFLDRFSGALVIY
GSVGAVEEALSQTVSGLGRLLNYTLCEMTKS
>SEQF1516_EDU86778.1 sigma-54 dependent response regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHKPAHLLLVDDDPGLLKLLGLRLTSEGYSVVTAESGAEGLRVLNREKVDLVISDLRMDEMDGMQLFAEIQKVQPGMPV
IILTAHGSIPDAVAATQQGVFSFLTKPVDKDALYQAIDDALEQSAPATDERWREAIVTRSPLMLRLLEQARLVAQSDVSV
LINGQSGTGKEIFAQAIHNASPRNSKPFIAINCGALPEQLLESELFGHARGAFTGAVSNREGLFQAAEGGTLFLDEIGDM
PAPLQVKLLRVLQERKVRPLGSNRDIDINVRIISATHRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANH
LLRQAAERHKPFVRAFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFVEARNQFEL
NYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE
>SEQF1516_EDU86779.1 sigma-E factor regulatory protein RseB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYELSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPR
REVVQRGNEISYFEPGLEPFTLNGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
DTESKLPMRVDLLDRDGETLEQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKAKFSWTPTWLPQGFSEVSSSRRP
LPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQMLRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGAAQ
>SEQF1516_EDU86780.1 Fe-S protein assembly co-chaperone HscB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQLAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLA
SEQHTVRDTAFLMEQLELREELDEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAAADTVRKLRFLDKLRSS
AEQLEEKLLDF
>SEQF1516_EDU86781.1 N-acetylmuramoyl-L-alanine amidase AmiA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKDEPLKTSNGHSKPKAKKSGGKRVVVLDPGHGGIDTGAIGRNGSKE
KHVVLAIAKNVRSILRNHGIDARLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMA
KYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKLHSRNTEQAAFVVLKSPSVPSVL
VETSFITNPEEERLLGTAAFRQKIATAIAEGVISYFHWFDNQKAHSKKR
>SEQF1516_EDU86782.1 peptidase, M48 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTLSIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLG
MRLVSHANSVKTPFHFFLINNDEINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRNAPLT
WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFDPQAMPTFLEKLLDQARYSSRPP
EILLTHPLPESRLADARNRANQMRPMVVQSSEDFYLAKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAM
EANKYDEARKTLQPLLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQPQEAANILN
RYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLLSSASSQVKLGSLQQARYDARIDQLRQLQER
FKPYTKM
>SEQF1516_EDU86783.1 hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQQITLIKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDRGNGATILLYNAKKKTVVLIRQFRVATWVNGNESGQL
IETCAGLLDNDEPEVCIRKEAIEETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDNQRANAGGGVEDEDIEVLELPF
SQALEMIKTGEIRDGKTVLLLNYLQMSHLID
>SEQF1516_EDU86784.1 beta-lactamase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRTMLYLSLLAVSCSVSAAKYPVLTESSPEKAGFNVERLNQMDRWISQQVDAGYPGVNLLIIKDNQIVYRKAWGAAKKY
DGSVLMAQPVKATTGTLYDLASNTKMYATNFALQKLMSEGKLHPDDLIAKYISGFADSPNDTIKGKNTLRISDLLHHSGG
FPADPQYPNKAVAGALYSQDKGQTLEMIKRTPLEYQPGSKHIYSDVDYMLLGFIVESVTGQPLDRYVEESIYRPLGLTHT
VFNPLLKGFKPQQIAATELNGNTRDGVIHFPNIRTSTHWGQVHDEKAFYSMGGVSGHAGLFSNTGDIAVLMQTMLNGGGY
GDVQLFSAETVKMFTTSSKEDATFGLGWRVNGNATMTPTFGTLASPQTYGHTGWTGTVTVIDPVNHMAIVMLSNKPHSPV
ADPQKNPNMFESGQLPIATYGWVVDQVYAALKQK
>SEQF1516_EDU86785.1 3-phenylpropionate dioxygenase beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAQVSLELHHRISQFLFHEASLLDDWKFRDWLAQLDEEICYTMRTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIAR
LETGMAWAEEPPSRTRHLISNCQISETDIPNVFAVRVNYLLYRAQKERDETFYVGTRFDKVRRLEDDNWRLLERDIVLDQ
AVITSHNLSVLF
>SEQF1516_EDU86786.1 GTP-binding protein LepA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLDYKASDGETYQLNFIDTPG
HVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVR
CSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLRKGDKVKVMSTGQTYNADRLGIF
TPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTLARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLN
DASLFYEPESSSALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPAVNNIYELR
EPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEVVLDFFDRLKSTSRGYASLDYNFKRFQASDM
VRVDVLINGERVDALALITHRDNSQNRGRELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISR
KKKLLQKQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK
>SEQF1516_EDU86787.1 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEATVNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVN
VPLVADIHFDYRIALKVAEYGVDCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLES
AMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAVKSAIGLGLLLSEGIGDTLRVSL
AADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQEFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGV
TGGNKKSGLYEDGVRKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK
>SEQF1516_EDU86788.1 cysteine desulfurase IscS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDN
LAIKGAANFYQKKGKHIITSKTEHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVV
QDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYVRRKPRVRIEAQMHGGGHERGMR
SGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNRLWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDL
AVSSGSACTSASLEPSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQGVDLNSIE
WAHH
>SEQF1516_EDU86789.1 ethanolamine utilization protein EutE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQQDIEQVVKAVLLKMQSSDTPPAAVHEMGVFASLDDAVAAAKIAQQGLKSVAMRQLAIAAIREAGEKHARDLAELAVS
ETGMGRVEDKFAKNVAQARGTPGVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAP
HPAAKKVSQRAITLLNQAIVAAGGPENLLVTVANPDIETAQRLFKFPGIGLLVVTGGEAVVEAARKHTNKRLIAAGAGNP
PVVVDETADLARAAQSIVKGASFDNNIICADEKVLIVVDSVADELMRLMEGQHAVKLTAEQAQQLQPVLLKNIDERGKGT
VSRDWVGRDAGKIAAAIGLKVPQETRLLFVETTAEHPFAVTELMMPVLPVVRVANVADAIALAVKLEGGCHHTAAMHSRN
IENMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSARTFVRLRRCVLVDAFRIV
>SEQF1516_EDU86790.1 serine hydroxymethyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAID
RAKELFGADYANVQPHSGSQANFAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEK
QAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGGLIL
AKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFL
VDLVDKNLTGKEADAALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEVEAKELAGWMCDVLDSINDEAVIE
RIKGKVLDICARYPVYA
>SEQF1516_EDU86791.1 malate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVAAPCLEIEKDPLKAYKYTARGNLVAVISNGTAVLGLG
NIGALAGKPVMEGKGVLFKKFAGIDVFDIEVDELDPDKFIEVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFH
DDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVVCDSKGVIYQGREPNMAETKAAY
AVVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKKMARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNN
VLCFPFIFRGALDVGATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKIAPAVAKAA
MESGVATRPIADFDVYIDKLTEFVYKTNLFMKPIFSQARKAPKRVVLPEGEEARVLHATQELVTLGLAKPILIGRPNVIE
MRIQKLGLQIKAGVDFEIVNNESDPRFKEYWTEYFQIMKRRGVTQEQAQRALISNPTVIGAIMVQRGEADAMICGTVGDY
HEHFSVVKNVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNDEPDAEELAEITLMAAETVRRFGIEPRVALLSHSNFGSS
DCPSSSKMRQALELVRERAPELMIDGEMHGDAALVEAIRNDRMPDSPLKGSANILVMPNMEAARISYNLLRVSSSEGVTV
GPVLMGVAKPVHVLTPIASVRRIVNMVALAVVEAQTQPL
>SEQF1516_EDU86792.1 formate hydrogenlyase maturation protein HycH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEECGEIVFWTLRKKFVASSDEMPEHSSQVMYYSLAIGHHVGVIDCLNVTFRCPLTEYEDWLALVEEEQARRKMLGVMT
FGEIVIDASHTALLTRAFAPLADDATSVWQARSIQFIHLLDEIVLEPAIYLMARKIA
>SEQF1516_EDU86793.1 RNA methyltransferase, TrmH family, group 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDSQAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTS
ARSRTLPWPMLDPRECGLKSVAEAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW
LATQENGEQVEHEETPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTRARPESQELNILRGILASIEQQN
KGNKA
>SEQF1516_EDU86794.1 hydrogenase-4 transcriptional regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMSDEAMFAPPQGITIEAVNGMLAERLAQKHGKASLLRAFIPLPPPFSPVQLIELHVLKSNFYYRYHDDGSDVTATTEY
QGEMVDYSRHAVLLGSSGMAELRFIRTHGSRFTPQDCTLFNWLARIITPVLQSWLNDEEQQVALRLLEKDRDHHRVLVDI
TNAVLSHLDLDDLIADVAREIHHFFGLASVSMVLGDHRKNEKFSLWCSDLSASHCACLPRNMPGDSVLLTQTLQTRQPTL
THRADDLFLWQRDPLLHLLASNGCESSLLIPLTFGNHTPGALLLAHTSTTLFSEENCQLLQHIADRIAIAVGNADAWRSM
TDLQESLQQENHQLSEQLLSNLGVGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLSPRRDKPLV
KINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGDLPLELQPKLLRVLQEREIERLGGSRTIPVN
VRVIAATNRDLWQMVEDRQFRSDLFYRLNVFPLELPPLRDRPEDIPLLAKHFTQKMARHMNRAIDAIPTEALRQLMSWDW
PGNVRELENVIERAVLLTRGNSLNLHLNVRQSRLLPTLNEDSALRSSMAQLLHPTTPENDEEERQRIVQVLRETNGIVAG
PRGAATRLGMKRTTLLSRMQRLGISVREVL
>SEQF1516_EDU86795.1 tetratricopeptide repeat protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYGVTDTLSEQKTLKSWQAVWLENDYIKVMILPELGGRV
HRAWDKVKQRDFVYHNEVIKPALVGLLGPWISGGIEFNWPQHHRPTTFMPVDFTLEAHEDGAQTVWVGETEPMHGLQVMT
GFTLRPDRAALEIASRVYNGNATPRHFLWWANPAVKGGEGHQSVFPPDVTAVFDHGKRAVSAFPIATGTYYKVDYSAGVD
ISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLHVANHHIAPGKKQWSWGHSEFGQAWDKSLTDNNGPYIELMTGIFA
DNQPDFTRLDAYEEKRFEQFFLPYHSLGMVQNASRDAVIKLQRSERGIEWGLYAISPLNGYRLAIREIGKCDALLDDAVA
LTPATAIQGVLHGINPERLTIELSDADGNIVLSYQEHQPQELPLPDVAKAPLSAQDITSTDEAWFIGQHLEQYHHASRSP
FDYYLRGVALDPLDYRCNLALAMLEYNRADFPQAVAYATQALKRAHALNKNPQCGQASLIRASAYERQGQYQQAEEDFWR
AVWSGNSKAGGYYGLARLAARNGNFDAGLDFCQQSLRACPINQEVLCLHNLLLVLSGRQDNARLQREKLLRDYPLNATLW
CLNWFDGRSESALAQWRGLCQGRDVNALMTAGQLINWGMPTLAAEMLNALDCQRTLPLYLQASLLPKAERGELVAKAIDV
FPQFVRFPNTLEEVAALESIEECWFARHLLACFYYNKRSYNEAIALWQRCVEMSPEFADGWRGLAIHAWNKQHDYELAAR
YLDNAYQLAPQDARLLFERDLLDKLSGTTPEKRLARLENNLEIALKRDDMTAELLNLWHLTGQADKAADILATRKFHPWE
GGEGKVTSQFILNQLLRAWQHLDAREPQQASELLHAALHYPENLSEGRLPGQTDNDIWFWQAICAKAQGDETEATRCLHL
AATGDRTINIHSYYNDQPVDYLFWQGMALRLLGEQHTAQQLFSEMKQWAQEMAKTSIEADFFAVSQPDLLSLYGDLQQQH
KEKCLMVAMLAAAGLGEIAQYESARAELTAINPAWPKAALFTTVMPFIFNYVH
>SEQF1516_EDU86796.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALPVNKRVPKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGPDPWSAESVEFTAKDGTRLQGWFIPSSTGPADNAIAT
IIHAHGNAGNMSAHWPLVSWLPERNFNVFMFDYRGFGKSKGTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
NILAVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIPLLLIHGKADHVIPWQHSEKLYS
LAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVNFILSALNPQN
>SEQF1516_EDU86797.1 ribonuclease III [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLGDSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNT
LAELAREFELGECLRLGPGELKSGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRL
QEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQALKKLELE
>SEQF1516_EDU86798.1 esterase, AB hydrolase 2 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHDHFVVQSPDKPAQQLLLLFHGVGDNPVAMGEIGSWFAPLFPDALVVSVGGAEPSGNPAGRQWFSVQGITEDNRQARV
DAIMPTFIETVRYWQKQSGVGANATALIGFSQGAIMALESIKAEPGLASRVIAFNGRYASLPETASTATTIHLIHGGEDP
VIDLAHAVAAQEALISAGGDVTLDIVEDLGHAIDNRSMQFALDHLRYTIPKHYFDEALSGGKPGDDDVIEMM
>SEQF1516_EDU86799.1 pyridoxine 5'-phosphate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITVHLREDRRHITDRDVRILRQTLDTRMNLEMAVTEEML
AIAVETKPHFCCLVPEKRQEVTTEGGLDVAGQRDKMRDACKRLADAGIQVSLFIDADEEQIKAAAEVGAPFIEIHTGCYA
DAKTDAEQAQELARIAKAATFAASLGLKVNAGHGLTYHNVKAIAAIPEMHELNIGHAIIGRAVMTGLKDAVAEMKRLMLE
ARG
>SEQF1516_EDU86800.1 glycine cleavage system transcriptional repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLSSQHYLVITALGADRPGIVNTITRHVSSCGCNIEDSRLAMLGEEFTFIMLLSGSWNAITLIESTLPLKGAELDLLIV
MKRTTARPRPPMPASVWVQVDVADSPHLIERFTALFDAHHMNIAELVSRTQPAENERAAQLHIQITAHSPASADAANIEQ
AFKALCTELNAQGSINVVNYSQHDEQDGVK
>SEQF1516_EDU86801.1 acriflavine resistance protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVRVTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSS
QSSGTGQASVTLSFKAGTDPDEAVQQVQNQLQSAMRKLPQAVQNQGLTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQLGGTPSVDKQALNATINAQSLL
QTPEQFRDITLRVNQDGSEVRLGDVATAEMGAEKYDYLSRFNGKPASGLGVKLASGANEMATAELVLNRLDELAQYFPHG
LEYKVAYETTSFVKASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNTLTMFAMVL
AIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGTTGAIYRQFSITIVAAMVL
SVLVAMILTPALCATLLKPLKKGEHHGQKGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPT
SFLPLEDRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVARMFIRLKDWSERDSKT
GTSFAIIERATKAFNQIKEARVIASSPPAISGLGSSAGFDMELQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLD
DSPQLQIDIDQRKAQALGVAIDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVPFS
AFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLEWTAMSYQERLSGAQAPALYAISLL
VVFLCLAALYESWSVPFSVMLVVPLGVIGALLATWMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEA
TLHACRQRLRPILMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRFPLKPRPE
>SEQF1516_EDU86802.1 ethanolamine utilization protein EutD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIERCCELALRAPARVVFPDALDQRVLKAAQYLHQQGLATPILVANPFELRQFALSHGVAMDGLQVIDPHGNLAMREEF
AHRWLARAGEKTPPDALEKLTDPLMFAAAMVSAGKADVCIAGNLSSTANVLRAGLRIIGLQPGCKTLSSIFLMLPQYSGP
ALGFADCSVVPQPTAAQLADIALASAETWRAITGEEPRVAMLSFSSNGSARHPCVANVQQATEIVRERAPKLVVDGELQF
DAAFVPEVAAQKAPASPLQGKANVMVFPSLEAGNIGYKIAQRLGGYRAVGPLIQGLAAPMHDLSRGCSVQEIIELALVAA
VPRQTEVNRESSLQTLVE
>SEQF1516_EDU86803.1 ethanolamine utilization protein EutG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGSVSSCGQQAQTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAM
TLWPCPVGEPCITDVCAAVAQLRESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAIEAYSALNATPFTDSLAIGAIAM
IGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAGLGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRERFSQ
IGRALRTKKSDDRDAINAVSELIAEVGIGKRLGDVGATSAHYGAWAQAALEDICLRSNPRTASLEQLVGLYAAAQ
>SEQF1516_EDU86804.1 uracil phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEATADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAG
LGMMDGVLENVPSARISVVGMYRNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLV
AAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK
>SEQF1516_EDU86805.1 transcriptional regulator, RpiR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEAGVSQSSVVKFAQKLGYKGFPALKLALSEALASQPES
PSVPIHNQIRGDDPLRLVGEKLIKENTAAMYATLNVNSEEKLHECVTMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPNALQQRASHCLYTIAEEQATNSA
SISACHAQGMLTDLLFIALIQQDLELAPERIRHSEALVKKLV
>SEQF1516_EDU86806.1 GMP synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEAQIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGV
PVFGVCYGMQTMAMQLGGHVEASNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAVARIREQVGDDKVILGLSGGVDS
SVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDMFGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFD
EEALKLEDVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELGLPYDMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE
>SEQF1516_EDU86807.1 putative dimethyl sulfoxide reductase subunit C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHELPLMAFTLLLQASVGMTLWLAFLHRHILITSSARPVMRPPLLLAFLAGAVGLLISTLHLGYPLNAMHALSHFSSSWL
SREIIFGALYLALLGLSTLLVMLRKGGWQLLLMLAAVVGIVDVFCMAQVYIHTSIITWQHYNTLIMFLGTVGILGSALVA
VFRISGILPQIDALRNGCVLVIALLVLLRLLVQPLWIGDLTANAMQIATLPHAPLAMLGQLKPILTLSWGISVIGMMFFA
VGGCKKNIPAALFGSVMLVGSEVMLRFVFFSIG
>SEQF1516_EDU86808.1 ethanolamine ammonia-lyase, large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQERVAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDV
NETAYNQIKNWSISELREYVLSDETSVDDIAFTRKGLTSEVVAAVAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSAR
LQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNIPTQGCVLAHVTTQIEAIRRGAP
GGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFNRIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDP
FIVNTVVGFIGPEYLYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIMGMPLGDDI
MLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPSLFF
>SEQF1516_EDU86809.1 putative transglycosylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGELRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGV
KLKVTVRQNISQLFDDLDNGNADLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVV
VNDLQTLKETKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELAVALDITDEQPVTWFSPLDGDNT
LSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVDTRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQ
ATSPTGVRGMMMLTKNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHMQDARALTAK
TKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQISLVGYLQEKEKQATEAAMQLAQDYPAVSPTE
LGKEKFPFLSFLSQSSSNYLTHSPSLLFSRKGSEEKQN
>SEQF1516_EDU86810.1 3-phenylpropionate dioxygenase ferredoxin--NAD(+) reductase component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDEQHLPYERPPLSKSMLLEDSPQLQSVLPAHWWQENNVHLHSGVT
IKTLGRDTRELVLANGESWHWDQLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELA
ASATQRRCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVVDGEKVELTLQSGETLQADVVIYGIGIS
ANDQLAREANLDTTNGIVIDEACRTCDPAIFAGGDVAITRLDNGALHRCESWENANNHAQIAAAAMLGLPLPLLPPPWFW
SDQYSDNLQFIGDMRGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRSIRKWIQSGKTFDAKQLTDENIALKSL
>SEQF1516_EDU86811.1 HAD hydrolase YhfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATHERRVVFFDLDGTLHQQDMFGSFLRYLLRRQPLNALLVLPLLPIIAIALLIKGRAARWPMSLLLWGCTFGHSEARLQ
ALQADFVRWFRDNVTAFPLVQERLTTYLLSSDADIWLITGSPQPLVEAVYFDTPWLPRVNLIASQIQRGYGGWVLTMRCL
GHEKVAQLERKIGTPLRLYSGYSDSNQDNPLLYFCQHRWRVTPRGELQQLE
>SEQF1516_EDU86812.1 N-acetylmuramic acid 6-phosphate etherase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERVLPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILD
ASECPPTYGVKPGLVVGLIAGGEYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
TVGISCNPGSAVSTTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGKVFGNLMVDVVATNEKLHVRQVN
IVKNATGCNAEQAEAALIACERNCKTAIVMVLKNLDAAEAKKRLDQHGGFIRQVLDKE
>SEQF1516_EDU86813.1 dimethylsulfoxide reductase, chain B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQFKEFASVSDKQLGFFIDSSRCSGCKACQVACKDKNNLEVGRRFRRVYEVNGGGFIATGEGGVSHNVFAYTLSVSCNH
CADPICTKNCPTMAMHKRPGDGIVRVNTDKCVGCGYCAWSCPYGAPQMNEQTGQMSKCDFCIDLQAKGEQPICVATCPLG
AIKFGPIDELREKYGDVSDVKGLPDSSITQPNLVIKPHQGAEKEASHHA
>SEQF1516_EDU86814.1 ferredoxin, 2Fe-2S type, ISC system [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKIVILPHQDLCPDGAVLEANSGETILDAALRNGIEIEHACEKSCACTTCHCIVREGFDSLPESSEQEDDMLDKAWGLE
PESRLSCQARVTDEDLVVEIPRYTINHAREH
>SEQF1516_EDU86815.1 peptidase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLIQRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKA
PKGTRKVEWPDLDDAQRQELDNRLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVASDRVTYRITKGEDLREQGYMGL
HTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSDMGGAATVTGALAFAITRGLNKR
VKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNTDAEGRLVLADGLIDASAQKPEMIIDAATLTGAAKTALGNDYHAL
FSFDDALAGRLLASASQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGWLHIDCSAT
YRKAPVEQWSAGATGLGVRTIANLLTA
>SEQF1516_EDU86816.1 phosphoribosylglycinamide formyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLERARQAGIATHTLIASAFDSREAYDRELIHEIDMYAP
DVVVLAGFMRILSPAFVSHYAGRLLNIHPSLLPKYPGLHPHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGD
TEDDVTARVQTQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQGYAADE
>SEQF1516_EDU86817.1 putative transcriptional regulator EutR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKTRTANLHHLYHEPLPENLKLTPKVEVDNVHQRQTTDVYEHALTITAWQQIYDQLHPGKFHGEFTEILLDDIQVFREY
TGLALRQSCLVWPNSFWFGIPATRGEQGFIGSQCLGSAEIATRPGGTEFELSTPDDYTILGVVLSEDVITRQANFLHNPD
RVLHMLRSQSALEVKEQHKAALWGFVQQALATFCENPENLHQPAVRKVLGDNLLMAMGAMLEEAQPMVTAESISHQSYRR
LLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNAFHAILGIGPNAWLKRIRLNAVRRELISPWSQSTTVKDAAMQWGF
WHLGQFATDYQQLFAEKPSLTLHQRMREWG
>SEQF1516_EDU86818.1 aldose 1-epimerase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIYTLSHGSLKLGVSDQGGVIEGFWRDTTPLLRPGKKSGVATDASCFPLVPFANRVSGNRFVWQGREYQLQPNVEWDAH
YLHGDGWLGEWQCVSHSDDSLCLVYEHRSGVYHYRVSQAFHLTADTLTVTLSVTNQGAETLPFGTGWHPYFPLSPQTRIQ
AQASGYWLEREQWLAGEFCEQLPQELDFNQLAPLPRQWVNNGFAGWNGQARIEQPQEGYAIIIETTPPAPCYFIFVSDPA
FDKGYAFDFFCLEPMSHAPDDHHRPEGGDLIALAPGESTTSEMSLRVEWL
>SEQF1516_EDU86819.1 ethanolamine utilization protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLAVVTGQIVCTVRHHGLAHDKLLMVEMIDPHGNPDGQCAVAIDNIGAGTGEWVLLVSGSSARQAHKSETSPVDLCVIG
IVDEVVSGGQVIFHK
>SEQF1516_EDU86820.1 4Fe-4S binding domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALLITKKCINCDMCEPECPNEAISMGDHIYEINSDKCTECVGHYETPTCQKVCPIPNTIVKDPQHVETEEQLWDKFVLM
HHADKI
>SEQF1516_EDU86821.1 hydrogenase-4 component B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDALQLLTWSLILYLFASLASLFLLGLDRLAIKLSGITSLVGGVIGIISGITQLHEGVTLVARFATPFDFADLTLRMDSL
SAFMVLVISLLVVVCSLYSLTYMREYEGKGAAAMGFFMNIFIASMVALLVMDNAFWFIVLFEMMSLSSWFLVIARQDKTS
INAGMLYFFIAHAGSVLIMIAFLLMGRESGSLDFASFRTLSLSPGLASAVFLLAFFGFGAKAGMMPLHSWLPRAHPAAPS
HASALMSGVMVKIGIFGILKVAMDLLAQTGLPLWWGILVMAIGAISALLGVLYALAEQDIKRLLAWSTVENVGIILLAVG
VAMVGLSLHDPLLTVVGLLGALFHLLNHALFKGLLFLGAGAIISRLHTHDMEKMGALAKRMPWTAAACLIGCLAISALPP
LNGFISEWYTWQSLFSLSRVEAVALQLAGPIAMVMLAVTGGLAVMCFVKMYGITFCGAPRSTHAEEAQEVPNTMIVAMLL
LAALCVLIALSASWLAPKIMHIAHAFTNTPPVTVASGIALVPGTFHTQVTPSLLLLLLLAMPLLPGLYWLWCRSRRAAFR
RTGDAWACGYGWENAMAPSGNGVMQPLRVVFSALFRLRQQLDPTLRLNKGLAHVTARAQSTEPFWDERVIRPIVSATQRL
AKEIQHLQSGDFRLYCLYVVAALVVLLIAIAV
>SEQF1516_EDU86822.1 oxidoreductase UcpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKLTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEKLADELCGRGHRCTAVVADVRDPASVAAAIKRAKEKE
GRIDILVNNAGVCRLGSFLDMSDDDRDFHIDINIKGVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKA
AIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTEMAKAIPLRRLADPLEVGELAAFLASDESS
YLTGTQNVIDGGSTLPETVSVGI
>SEQF1516_EDU86823.1 ethanolamine utilization protein, EutP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRIAFVGTVGAGKTTLFNALQGNYTLARKTQAVEFNDKGDIDTPGEYFSHPRWYHALITTLQDVDMLIYVHGANDPESR
LPAGLLDIGVSKRQIAVISKTDMPDADVAATRKLLLETGFEEPIFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHSE
>SEQF1516_EDU86824.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRYRIFLLFFFALLPTSLVWAAPAQRAFSDWQVTCNNQNFCVARNTGDHNGLVMTLSRSAGAHTDAVLRIERGGLKSPDA
SEGEIAPRLLLDGEPLALSGDKWRISPWLLVTDDTATITAFLQMIQEGKAITLRDGNQTISLSDLKAALLFIDAQQKRVG
SETAWIKKGDEPPLSVPPAPALKEVVVVNPTPTPLSLEERNDLLDYGNWRMNGLRCSLDPLRREVNVTALTDDKALMMIS
CEAGAYNTIDLAWIVSRKKPLASRPVRLRLPFNNGQETNELELMNATFDEKSRELVTLAKGRGLSDCGIQARWRFDGQRF
RLVRYAAEPTCDNWHGPDAWPTLWITR
>SEQF1516_EDU86825.1 nitrate/nitrite sensor histidine kinase NarQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVKRPVSASLARAFFYIVLLSILSTGIALLTLASSLRDAEAINIAGSLRMQSYRLGYDLQSGTPQLNAHRQLFQQALHS
PVLTNLNVWYVPEAVKTRYAHLNANWLEMNNRLSKGDLPWYQANINNYVNQIDLFVLALQHYAERKMLLVVAISLAGGIG
IFTLVFFTLGRIRHQVVAPLNQLVTASQRIEHGQFDSPPLDTSLPNELGLLAKTFNQMSSELHKLYRSLEASVEEKTRDL
HEAKRRLEVLYQCSQALNTSQIDVHCFRHILQIVRDNEAAEYLELNVGENWRISEGQPNPELPMQILPVTMQETVYGELH
WQNSHVSSSEPLLNSVSSMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRSIPEDNATAQS
IMADFSQALNDAYRQLRELLTTFRLTLQQADLPSALREMLDTLQNQTSAKLTLDCRLPTLALDAQMQVHLLQIIREAVLN
AMKHANASEIAVSCVTAPDGNHTVYIRDNGIGIGEPKEPEGHYGLNIMRERAERLGGTLTFSQPSGGGTLVSISFRSAEG
EESQLM
>SEQF1516_EDU86826.1 ethanolamine utilization protein EutJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAHDEQWLTPRLQTAATLCNQTPAATESPLWLGVDLGTCDVVSMVVDRDGQPVAVCLDWADVVRDGIVWDFFGAVTIVRR
HLDTLEQQFGRRFSHAATSFPPGTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVT
YSADEATGGHHISLTFAGNRRISLEEAEQYKRGHGEEIWPTVKPVYEKMADIVARHIEGQGITDLWLAGGSCMQPGVAEL
FRKQFPALQVHLPQHSLFMTPLAIASSGREKAEGLYAK
>SEQF1516_EDU86827.1 DnaA family protein Hda [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNFSRFCEILVEVSLNTPAQLSLPLYLPDDETFASFWPGDNSSLLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACA
ELSQRGDAVGYVPLDKRTWFVPEVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNL
GLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRTLFMTLDQLDRASITAQRKLTIP
FVKEILKL
>SEQF1516_EDU86828.1 3-phenylpropionate dioxygenase ferredoxin subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRIYACPVADVPEGEALRIDTSPVIALFNVGGEFYAINDRCSHGNASMSEGYLEDDATVECPLHAASFCLKTGKALCLP
ATDPLTTYPVHVEGGDIFIDLPEAQP
>SEQF1516_EDU86829.1 polyphosphate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSNNLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKI
QSRVLKADQEFDGLYNELLLEMARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILINPDTDLVQFLKDDYTYLAVE
IIRGDTIRYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYDALNAYSMKMTRDAEYDLVHEME
ASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVLREKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLR
HIWFDKAQFRNGFDAIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHNGKKVTVVV
ELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVVRYAHIGTGNFNEKTARLYTDYSLLTADARI
TNEVRRVFNFIENPYRPVTFDYLMVSPQNSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASSSGVPVN
LLVRGMCSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEVATPLLDPRLKQRVLDI
IDILFSDTVKARYIDKELSNRYVPRGNRRKVRAQLAIYDYIKSLEQPE
>SEQF1516_EDU86830.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQATSMRKRHRFNSRMTRIVLLISFIFFFGRFIYSSVGAWQHHQSKKEAQQSTLSVESPVQR
>SEQF1516_EDU86831.1 Fe-S protein assembly chaperone HscA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTAN
TISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYF
DDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDD
FDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALK
DAGVEADEVLEVVMVGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVIPLSLGLET
MGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRSLARFALRGIPALPAGGAHIRVTFQVDADGL
LSVTAMEKSTGVEASIQVKPSYGLTDSEIASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQ
VIDDAAAHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV
>SEQF1516_EDU86832.1 outer membrane assembly lipoprotein YfgL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTPTTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGL
VKALNADDGKEIWSVSLAEKDGWFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDG
LVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPATAFGAAVVGGDNGRVSAVLMEQGQMIWQQRISQATGSTE
IDRLSDVDTTPAVVNGVVFALAYNGNLTALDLRSGQIMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQS
DLLHRLLTSPVLYNGNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSITR
>SEQF1516_EDU86833.1 GTP-binding protein Era [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNK
AASSSIGDVELVIFVVEGTRWTPDDEMVLNKLREGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGL
NVATIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVERE
GQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLELWVKVKSGWADDERALRSLGYVDDL
>SEQF1516_EDU86834.1 flavohemoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFNMSNQRNGDQREALFNAIAAYASNIENLPALLPAVEK
IAQKHTSFQIKPEQYNIVGEHLLATLDEMFSPGQEVLDAWGKAYGVLANVFINREAEIYNENASKAGGWEGTRDFRIVAK
TPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYRIAVKREEGGQVSNWLHNHANVG
DVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLAMLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGQSLPRFTA
HTWYRQPSEADRAKGQFDSEGLMDLSKLEGAFSDPTMQFYLCGPVGFMQFAAKQLVDLGVKQENIHYECFGPHKVL
>SEQF1516_EDU86835.1 putative permease, PerM family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLEMLMQWYRRRFSDPEAIALLVILVAGFGIIFFFSGLLAPLLVAIVLAYLLEWPTVRLQSIGCSRRWATSIVLVVFVGI
LLLMAFVVLPIAWQQGIYLIRDMPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRSRMLTMGDSVVKISLASLVGLL
TIAVYLVLVPLMVFFLLKDKEQMLNAVRRVLPRNRGLAGQVWKEMNQQITNYIRGKVLEMIVVGIATWLGFLLFGLNYSL
LLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGAGTEFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFG
GLWGFWGVFFAIPLATLIKAVIHAWPDGQIAQE
>SEQF1516_EDU86836.1 putative ethanolamine utilization protein EutK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINALGLLEVDGMVAAIDAADAMLKAANVRLLSHEVLDPGRLTLVVEGDLAACRAALDAGCAAAMRTGRVISRKEIGRPD
DDTQWLVTGFNRQPKQPVKEPDAPVIVAESADELLALLTSVRQGVTAGEVAAHFGWPLEKARNALEQLFSAGTLRKRSSR
YRLKPH
>SEQF1516_EDU86837.1 radical SAM enzyme, Cfr family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQVMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAP
EVVEEQRSSDGTIKWAIAVGDQRVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVG
AAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPALDKLGDMIDVALAISLHAPNDE
IRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVTIEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPAAPYG
RSSNSRIDRFSKVLMSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV
>SEQF1516_EDU86838.1 Hca operon transcriptional activator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMELRHLRYFVAVAQALNFTRAAEKLHTSQPSLSSQIRDLENCVGVPLLVRDKRKVALTAAGECFLQDALAILEQAENAK
LRARKIVQEDRQLTIGFVPSAEVNLLPKVLPMFRLRQPDTLIELVSLITTQQEEKIRRGELDVGLMRHPVYSPEIDYLEL
FDEPLVVVLPVDHPLAHEKEITAAQLDGVNFVSTDPAYSGSLAPIVKAWFAQENSQPNIVQVATNILVTMNLVGMGLGVT
LIPGYMNNFNTGQVVFRPIAGNVPSIALLMAWKKGEMKPALRDFIAIVQERLASVTA
>SEQF1516_EDU86839.1 putative sugar ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSASSLPLPQGKSVSLKQFVSHHINEIGLLVVIAILYLVFSLNAPGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEID
VSVGPMVAFVSVCLAFLLQFEVPLAIACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPID
ENEVLDWLGGQFLGVPVSALIMMVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGINVRRVRILIFTLSGLLAAVTGIL
LAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRGSLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLAN
ILLTQRSSKAKR
>SEQF1516_EDU86840.1 FeS cluster assembly scaffold IscU [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYSEKVIDHYENPRNVGSFDNNDENVGSGMVGAPACGDVMKLQIKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGK
SLDEAQAIKNTDIAEELELPPVKIHCSILAEDAIKAAIADYKSKREAK
>SEQF1516_EDU86841.1 nucleoside diphosphate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTVEQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGE
NAVQRHRDLLGATNPANALAGTLRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR
>SEQF1516_EDU86842.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDWLAKYWWILVIVFLVGVLLNVIKDLKRVDHKKFLANKPELPPHRDFNDKWDDDDDWPKKDQPKK
>SEQF1516_EDU86843.1 iron-sulfur cluster assembly protein IscA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEFVDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFV
KEGLNEGFKFTNPNVKDECGCGESFHV
>SEQF1516_EDU86844.1 ethanolamine utilization protein EutA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTRQLLSVGIDIGTTTTQVIFSHLELVNRAAVSQVPRYEFIKREISWQSPVFFTPVDKQGGLKEAELKSLILEQYQAAG
IAPESVDSGAIIITGESAKTRNARPAVMALSQSLGDFVVASAGPHLESVIAGHGAGAQTLSEQRLCRVLNIDIGGGTANY
ALFDAGKISGTACLNVGGRLLETDSQGRVVYAHKPGQMIVDECFGAGTDVRSLTGAQLVQVTRRMAELIVEVIDGTLSPL
AQALMQTGLLPAGVTPEIITLSGGVGECYRHQPADPFCFADIGPLLATALHDHPRLREMNVQFPAQTVRATVIGAGAHTL
SLSGSTIWLEGVQLPLRNLPVAIPIDETDLVSAWQQALIQLDLDPKTDAYVLALPASLPVRYAAVLTVINALVDFVARFP
NPHPLLVVAGQDFGKALGMLLRPQLQQLPLAVIDEVIVRAGDYIDIGTPLFGGSVVPVTVKSLAFPS
>SEQF1516_EDU86845.1 hydrogenase-4 component D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENLALTTLLLPFIGALVVSFSPQRRAAEWGVLFAALTTLCMLSLISAFYQADKVAVTLTLVNVGDVALFGLVIDRVCTL
ILFVVVFLGLLVTIYSTGYLTDKNREHPHNGTNRYYAFLLVFIGAMAGLVLSSTLLGQLLFFEITGGCSWVLISYYQSDK
AQRSALKALLITHIGSLGLYLAAATLFLQTGTFALSAMSELHGDARYLVYGGILFAAWGKSAQLPMQAWLPDAMEAPTPI
SAYLHAASMVKVGVYIFARAIIDGGNIPHVIGGVGMVMALVTILYGFLMYLPQQDMKRLLAWSTITQLGWMFFGLSLSIF
GSRLALEGSIAYIVNHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLHTLPLPGVGFCVAALAITGVPPFNGFFSKFPLFA
AGFALSVEYWILLPAMILLMIESVASFAWFIRWFGRVVPGKPSEAVADAAPLPGSMRLVLIVLIVMSLISSVIAATWLQ
>SEQF1516_EDU86846.1 ethanolamine utilization protein EutH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGSGGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVI
IPVYEMLGANPSMFAGTLLACDMGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
GIVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVIIVAILVALGLKFIPEKMINGFQIFAKFLVALITLGLA
AAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEVIGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMV
ATLANNIPMFGMMKQMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLVPKDDATAA
KTEAEAQS
>SEQF1516_EDU86847.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNHNKPAIDTPAEEKIPVYQLADYLSTECSDIWALQGKSTETNPLYWLRAMDCADRLMPAQSRQQARQYDDGSWQNTFK
QGILLADAKITPYERRQLVARIEALSTEIPAQVRPLYQLWRDGQALQLQLAEERQRYSKLQQSSDSELDTLRQQHHVLQQ
QLELTTRKLENLTDIERQLSTRKPAGNFSPDTPHESEKPAPSTHEVTPDEP
>SEQF1516_EDU86848.1 hydrogenase-4, F subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYSVMFALLLLTPLLFSLLCFACRKRGHSATRTVTVLHSLGITLLLILALWVVQTAADAGEIFAAGLWLHIDGLGGLFL
AILGVIGFLTGVYSIGYMRHEVEHGELSPVTLCDYYGFFHLFLFTMLLVVTSNNLIVMWAAIEATTLSSAFLVGIYGQRS
SLEAAWKYIIICTVGVAFGLFGTVLVYANAASVMPQAEMAIFWSEVLKQSSLLDPTLMLLAFVFVLIGFGTKTGLFPMHA
WLPDAHSEAPSPVSALLSAVLLNCALLVLIRYYIIICQAIGSDFPNRLLLIFGMLSVAVAAFFILVQRDIKRLLAYSSVE
NMGLVAVALGIGGPLGIFAALLHTLNHSLAKTLLFCGSGNVLLKYGTRDLNVVCGMLKIMPFTAVLFGGGALALAGMPPF
NIFLSEFMTVTAGLARNHLLIIVLLLLLLTLVLAGLVRMAARVLMAKPPQAVNRGDLGWLTTSPMVILLVMMLAMGTHIP
QPVIRILAGASTIVLSGTHDLPAQRSTWHDFLPSGTASVSEKHSER
>SEQF1516_EDU86849.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKVFLCAILASLSYPAIASSLQDQLSAVAEAEQQGKNEEQRQHDEWVAERNREIQQEKQRRANAQAAANKRAATAAANK
KARQDKLDAEATADKKRDQSYEDELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANRNMTEGGR
DLMKSVGKAEENKSDSWFN
>SEQF1516_EDU86850.1 ROK family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAVSNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEG
DWTLCLNVTPTSIECQVANACLSPKGEFEYLQIDAPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIGSSFVINEQIYRGSLYGSGQIGH
TIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLKSQPVNTQLDPEKLTTAQLIAAWQSGEPWITSWVDRSANAIGLSL
YNFLNILNINQIWLYGRSCAFGEHWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVETQLRQI
>SEQF1516_EDU86851.1 iron-sulfur cluster assembly transcription factor IscR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQLFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVI
SAVDESVDATRCQGKGGCQGGDKCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKL
RA
>SEQF1516_EDU86852.1 phosphoribosylformylglycinamidine synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLNAPLNDDEHAQLERLLKYGPALASHAPQGKLLLVTPR
PGTISPWSSKATDIAHNCGLQQVNRLERGVAYYIEAGTLTNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTS
VDLLGQGRQALIDANLRLGLALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHETGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEG
ATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVNSHN
GEELRGYHKPIMLAGGIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQL
PLFDELCKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGDALVREGITIADAVKRV
LHLPTVAEKTFLVTIGDRSVTGMVARDQMVGPWQVPVANCAVTTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEAL
TNIAATQIGDIKRIKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEGNEEREMTSPLSL
VISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGATALAQVYRQLGDKPADVRDVAQLKGFYDAIQALVAQRKLL
AYHDRSDGGLLVTLAEMAFAGHCGIDADIATLGDDRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVS
GDRFVITANGQTVFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINEDVAAPYIATGARP
KVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRTGLEDFHALVACGGFSYGDVLGAGEGWAKSILFNDRVRDEF
ATFFHRPQTLALGVCNGCQMMSNLRELIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGR
VEVRDAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHPERVFRTVSNSWHPENWGED
GPWMRIFRNARKQLG
>SEQF1516_EDU86853.1 PTS system, N-acetylmuramic acid-specific EIIBC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVDPDIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMS
ELLGEAPVQDAAEIAAQNKRQLKAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALN
FMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDFFGLPIDPRGNIIGVLIAAWACA
RIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIMPLGGWLFEGMSWLFMHLNSNPLGCAVLAGLFLIAVVFGVHQGFI
PVYLALMDSQGFNSLFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMKPFITACLG
GAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAGGILVAWVCGFIFTTLFGCRNVNLD
>SEQF1516_EDU86854.1 hydrogenase-4 component E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTGSMIVNNLAGLMMLTSLFVISVKSYRLSCGFYACQSLVLVSIFATLSCLFAAEQLLIWSASAFITKVLLVPLIMTYAA
RNIPQNIPEKALFGPAMMALLAALIVLLCAFVVQPVKLPMATGLKPALAVALGHFLLGLLCIVSQRNILRQIFGYCLMEN
GSHLVLALLAWRAPELVEIGIATDAIFAVIVMVLLARKIWRTHGTLDVNNLTALKG
>SEQF1516_EDU86855.1 signal peptidase I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANMFALILVIATLVTGILWCVDKFFFAPKRRERQAAAQAAAGDSLDKATLKKVAPKPGWLETGASVFPVLAIVLIVRSF
IYEPFQIPSGSMMPTLLIGDFILVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDP
VSKELTIQPGCSSGQACENALPVTYSNVEPSDFVQTFSRRNGGEATSGFFEVPKNETKENGIRLSERKETLGDVTHRILT
VPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNRDNSADSRYWGFVPEANLVGRATAIWMSFDKQEGEWPTGVRLSRI
GGIH
>SEQF1516_EDU86856.1 putative polyferredoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSHNITIGAECARQRFRFATCHACVEACPAQALTLTEEGIAVDAEQCIDCAVCQFICPQEAIRGVNSPLRYFCNHTLVA
PFTTIAPTLEELLLWHKEQGITAIAIDLSQAKAWERALLLLNECLRQYGEEGWSVVSPHTSEVNVSRRRLFHVQRADVQM
TQIQPGLRRLHYLWPQISDARPMMDPQKCQLCGACWRACEQQVFSLNEGHLQINDALCNGCQNCIAVCFHQAMTVELTIL
PAKIVNLHANRKVCKTCQKSFLTFQQNAQNCLYCQRHRYGMRTP
>SEQF1516_EDU86857.1 putative sugar ABC transporter, periplasmic sugar-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKKMRTTRNLLLMATLLGSALFARAADKEMTIGAIYLDTQGYYAGVRQGVQDAAKDSSVQVQLIETNAQGDISKESTFV
DTLVARNVDAIILSAVSENGSSRTVRRASEAGIPVICYNTCINQKGVDKYVSAYLVGDPLEFGKKLGNAAADYFIANKID
QPKIAVINCEAFEVCVQRRKGFEEVLKSRVPGAQIVANQEGTVLDKAISVGEKLIISTPDLNAIMGESGGATLGAVKAVR
NQNQAGKIAVFGSDMTTEIAQELENNQVLKAVVDISGKKMGNAVFAQTLKVINKQADGEKVIQVPIDLYTKTEDGKQWLA
THVDGLP
>SEQF1516_EDU86858.1 ethanolamine utilization protein EutM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEALGMIETRGLVALIEASDAMVKAARVKLVGVKQIGGGLCTAMVRGDVAACKAATDAGAAAAQRIGELVSVHVIPRPHG
DLEEVFPIGLKGDSSNL
>SEQF1516_EDU86859.1 transaldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGLSQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNF
GAEILKIVPGRVSTEVDARLSFDKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYETIVMGASFRRTEQILALTGCDR
LTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMSEAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL
>SEQF1516_EDU86860.1 inosine-5'-monophosphate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSVTLCIMPRQYLLTTLVEILPMLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPMLSAAMDTVTEARL
AIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLPTTTLREVKELTERNGFAGYPVVTEENELVGIITGR
DVRFVTDLNQPVSVYMTPKERLVTVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGR
LRVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGGNVATAAGARALAEAGCSAVKV
GIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIPVIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELY
QGRSYKSYRGMGSLGAMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTIDELRTKA
EFVRISGAGIQESHVHDVTITKESPNYRLGS
>SEQF1516_EDU86861.1 dyp-type peroxidase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQVQSGILPEHCRAAIWIEANVKGEVDALRAASKTFADKLATFEAKFPDAHLGAVVAFGNNIWRALSGGVGAEELKDFP
GYGKGLAPTTQFDVLIHILSLRHDVNFSVAQAAMEAFGDCIEVKEEIHGFRWVEERDLSGFVDGTENPAGEETRREVAVI
KDGVDAGGSYVFVQRWEHNLKQLNRMSVHDQEMMIGRTKEANEEIDGDERPETSHLTRVDLKEDGKGLKIVRQSLPYGTA
SGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAMLRFTKPVTGGYYFAPSLDKLMAL
>SEQF1516_EDU86862.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAELTALHTLTAQMKREGIRRLLVLSGEEGWCFDHALKLRDALPGDWLWISPQPDAENHCSPSALQTLLGREFRHAVFDA
RHGFDAAAFAALSGTLKAGSWLVLLLPVWEEWENQPDADSLRWSDCPDPIATPHFVQHFKRVLTADNDAIFWRQNQPFSL
AHFTPRTDWHPATGAPQPEQQQILQQLLTMPSGVAAVTAARGRGKSALAGQLISRIAGSAIITAPAKAATDVLAQFAGEK
FRFIAPDALLASDEQADWLVVDEAAAIPAPLLHQLVSRFPRTLLTTTVQGYEGTGRGFLLKFCARFPHLHRFELQQPIRW
AQGCPLEKMVSEALVFNDENFTHTPQGNIVISAFEQTLWRSEPETPLKVYQLLSGAHYRTSPLDLRRMMDAPGQHFLQAA
GENEIAGALWLVDEGGLSQELSQAVWAGFRRPRGNLVAQSLAAHGSNPLAATLRGRRVSRIAVHPARQREGVGQQLIASA
LQYRPGLDYLSVSFGYTGELWRFWQRCGFVLVRMGNHREASSGCYTAMALLPMSDAGKQLAEREHYRLRRDAQALAQWNG
ETLPVDPLNNAVLSDDDWLELAGFAFAHRPLLTSLGCLLRLLQTSELALPALRGRLQKNVSDAQLCTTLKLSGRKMLLVR
QREEAAQALFALNDVRTERLRDRITQWQFFH
>SEQF1516_EDU86863.1 penicillin-binding protein 1C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRLLTKRGCWITLAAAPFLLFLAAWGADKLWPLPLHEVNPARVVVAQDGTPLWRFADADGIWRYPVTIEDVSPRYLEAL
INYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGSTLTMQVARLLDPHPKTFGGKIRQLWRALQLEWHLSKREILTLY
LNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAMLAVLPQAPSRLRPDRWPERAEVARNKVLERMAVQGVWSREQVKES
REEPIWLAPRQMPQLAPLFSRMMLGKSKSDKIVTTLDAGLQRRLEELAQNWKGRLPPRSSLAMIVVDHTDMRVRGWVGSV
DLNDDSRFGHVDMVNAIRSPGSVLKPFVYGLALDEGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPISMSEALVRSLNLP
AVQVLEAYGPKRFAAKLRNVGLPLYLPNGAAPNLSLILGGAGAKLEDMAAAYTAFARHGKAGKLRLQPDDPLLERPLMSS
GAAWIIRRIMADEALPLPDGALPRVAPLAWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTPVVGQFGFASAVPLLNQV
NNILLSRSANLPEDPRPNSVTRGVICWPGGQSLPEGDGNCRRRLATWLLDGSQPPTLLLPEQEGINGIRFPIWLDENGKR
VAADCPQARQEMINVWPLPLEPWLPASERRAVRLPPASTICPPYGHDAQLPLQLTGVRDGEIIKRLPGAAEATLPLQSSG
GAGERWWFLNGEPLTERGRNVTLHLTDKGDYQLLVMDDVGQIASVHFSFQ
>SEQF1516_EDU86864.1 hydrogenase-4, I subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSPVLTQHVSQPITLDEQTQKMKRHLLQDIRRSAYVYRVDCGGCNACEIEIFAAITPVFDAERFGIKVVSSPRHADILLF
TGAVTRAMRMPALRAYESAPDHKICVSYGACGVGGGIFHDLYSVWGGSDTIVPIDVWIPGCPPTPAATIHGFAVALGLLQ
QKIHAVDYRDPTGVTMQPLWPQIPPSQRIAIEREARRLAGYRQGQEICDRLLRHLSNDPTGNRVNTWLRDADDPRLNSIV
QQLFRVLRGLHD
>SEQF1516_EDU86865.1 3-phenylpropionic acid transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVLQSTRWLALGYFTYFFSYGIFLPFWSVWLKGIGLTPETIGLLLGAGLVARFLGSLLIAPRVSDPSRLISALRVLALLT
LLFAVAFWAGAHVAWLMLVMIGFNLFFSPLVPLTDALANTWQKQFPLDYGKVRLWGSVAFVIGSALTGKLVTMFDYRVIL
VLLTLGVASMLLGFLIRPTIQPQGASRQQESTGWSAWLALVRQNWRFLACVCLLQGAHAAYYGFSAIYWQAAGYSASAVG
YLWSLGVVAEVIIFALSNKLFRRCSARDMLLISAICGVVRWGIMGATTALPWLIVVQILHCGTFTVCHLAAMRYIAARQG
SEVIRLQAVYSAVAMGGSIAIMTVFAGFLYQYLGHGVFWVMALVALPAMFLRPKVVPSC
>SEQF1516_EDU86866.1 inositol-1-monophosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQ
WVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNYMLTG
NIVAGNPRVVKAMLANMRDELSDALKR
>SEQF1516_EDU86867.1 uracil permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPATVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVL
LLLPLGYEVALGGFIMCGVLFCLVSFIVKKAGTGWLDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPDSKTII
ISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTLYTPRFEWFAILTILPAALVVIA
EHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVISGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVG
KLAAAIQMIPLPVMGGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGMALATIVGI
GLSLIFKLISVLRPEEVVLDAEDADITDK
>SEQF1516_EDU86868.1 succinyl-diaminopimelate desuccinylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMDFADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWIN
PPFEPTIRDGMLFGRGAADMKGSLAAMVVAAERFVAQHPNHTGRLAFLITSDEEASAHNGTVKAVEALMARNERLDYCLV
GEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIEWDQGNEFFPATSMQIANIQAGT
GSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLEKHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLT
TGGTSDGRFIARMGAQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA
>SEQF1516_EDU86869.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEIYENENDQVEAIKRFFAENGKALAVGVILGVGALIGWRYWNSHQVDSARSASLAYQNAVTAVSEGKPDSIPAAEKFAA
ENKNTYGALASLELAQQFVDKNELEKAAAQLQQGLADTSDENLKAVINLRLARVQVQLKQADAALKTLDTIKGEGWAAIV
ADLRGEALLSKGDKQGARSAWEAGVKSDVTPALSEMMQMKINNLSI
>SEQF1516_EDU86870.1 hydrogenase-4, G subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVNSSSNRGEAILAALKTQFPGAVLDEERQTPEQVTITVKINLLPDVVQYLYYQHDGWLPVLFGNDERTLNGHYAVYYA
LSMEGAEKCWIVVKALVDADSREFPSVTPRVPAAVWGEREIRDMYGLIPVGLPDQRRLVLPDDWPEDMHPLRKDAMDYRL
RPEPTTDSETYPFINEGNSGARVIPVGPLHITSDEPGHFRLFVDGEQIVDADYRLFYVHRGMEKLAETRMGYNEVTFLSD
RVCGICGFAHSVAYTNSVENALGIEVPQRAHTIRSILLEVERLHSHLLNLGLSCHFVGFDTGFMQFFRVREKSMTMAELL
TGSRKTYGLNLIGGVRRDILKEQRLQTLKLVREMRADVSELVEMLLATPNMEQRTQGIGILDRQIARDYSPVGPLIRGSG
FARDLRFDHPYADYGNIPKTLFTFTGGDVFSRVMVRVKETFDSLAMLEFALDNMPDTPLLTEGFSYKPHAFALGFVEAPR
GEDVHWSMLGDNQKLFRWRCRAATYANWPVLRYMLRGNTVSDAPLIIGSLDPCYSCTDRVTLVDVRKRQSKTVPYKEIER
YGIDRNRSPLK
>SEQF1516_EDU86871.1 hypothetical protein ECH7EC4501_1320 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVAAKASTFDAHTDNPTVVACAWGLFYLIRRYRGGSQP
>SEQF1516_EDU86872.1 nitrogen regulatory protein P-II 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTELYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRT
AQTGKIGDGKIFVFDVARVIRIRTGEEDDAAI
>SEQF1516_EDU86873.1 formate/nitrite transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNKLSFDLQLSARKAAIAERIAAHKIARSKVSVFLMAMSAGVFMAIGFTFYLSVIADAPSSQALTHLVGGLCFTLGFIL
LAVCGTSLFTSSVMTVMAKSRGVISWRTWLINALLVACGNLAGIACFSLLIWFSGLVMSENAMWGVAVLHCAEGKMHHTF
TESVSLGIMCNLMVCLALWMSYCGRSLCDKIVAMILPITLFVASGFEHCIANLFVIPFAIAIRHFAPTSFWQLAHSSADN
FPALTVSHFITANLLPVMLGNIIGGAVLVSICYRAIYLRQES
>SEQF1516_EDU86874.1 phosphoribosylformylglycinamidine cyclo-ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGGFGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRH
DTIGIDLVAMCVNDLVVQGAEPLFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFC
VGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPLADHLLAPTRIYVKSVLELIEKV
DVNAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQWPEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALL
NANGENAWKIGIIKASDSEQRVVIE
>SEQF1516_EDU86875.1 dihydrodipicolinate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGTTGESATLNHDEHADVVMMTLELADGRIPVIAGTGAN
ATAEAISLTQRFNDSGIVGCLTVTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGI
KEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMCKLAAEGHFAEARVINQRLMPLH
NKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITDSGRETVRAALKHAGLL
>SEQF1516_EDU86876.1 ribosome-associated GTPase EngA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIE
EADVVLFMVDARAGLMPADEAIAKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTLTNRILGEERVVVYDMPGTTRDS
IYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVIKTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVV
NKWDGLSQEVKEQVKETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAVEDHQPPLV
RGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMGSPIRIQFKEGENPYANKRNTLTPTQMRKRK
RLMKHIKKNK
>SEQF1516_EDU86877.1 peroxiredoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTPGCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSR
FAEKELLNFTLLSDEDHQVCEQFGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFDDFKTSNHHDVVLNWLKEHA
>SEQF1516_EDU86878.1 phosphoribosylaminoimidazole-succinocarboxamide synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECL
VKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKAND
VLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD
>SEQF1516_EDU86879.1 coproporphyrinogen III oxidase, aerobic [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPDAHQVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREGGGGGRSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPE
LAGRSFEAMGVSLVVHPHNPYVPTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGKDVY
PRYKKWCDDYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTDAYLPIVERRKAMAYGERERNFQLYRRGRY
VEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEYDYQPKDGSPEAALSEFIKVRDWV
>SEQF1516_EDU86880.1 anaerobic dimethyl sulfoxide reductase chain a [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDTPDEKERITFPQVSRRSFLQATSALITLPFISSTAKAQSPDASPEVTAPVADKVVPTCSTFDCGGKCDIRAHMRDGVV
TQITTLPDNELDPQMPIMRACVRGRGYRKFVYHPDRLKYPMKRVGKRGEGKFERISWDEATTLIADNLKRITQQYGPASR
YVHVGTAVSGGTFSGDAMARRLLNLTGGYLEYYHSVSLGNTAAATPYTYGVAASGNSMDTLLDTKLVILWGHNPTETIFG
HTNYYFQKMKQNGTRFIVVDPRYSDTVSSLADQWIPLLPTTDNALMDAMMYVIISENLHDKTFIDTYTLGFDENSMPEGV
PANESLVAYLFGAKDGIHKTPEWAEKITHVPAQSIRQLARDYATTKPAALIQGWGPQRHICGERTARGSTLLASITGNVG
IKGGWAAGYGGSSNRKFCVGPDMPENPVQAKISIMNWMQAADDASKVTPQDGLKGVDKLDSNIRLLFSLAGNYLANQNPD
VHQAAKLLEDESKIEFIVLSDLFMTPSAKYADVLLPETSFMERWNIGETWGTASYLILSEKPIEPDFERRTDYDWLRDVA
KKLGVEAEFSQGRDEKQWIEHIWEQTRLAMPDENLPDFATLQKTRRHLFKSAPHIAFEANIRDPQNNPFPTPSGKIEIFS
KRLFDMQDPEIPALSHYVPAFEGPEDKLTAKYPLQLITWKGKNRANSTQYANPWLQEVQTQKLWLNPQDAKQRGISEGDS
VKIYNDRGVSIIPVEITPRIIPGVVAMQAGAWWQPDAQGIDRGGCANVLSSTRITALAKGNSHQTMLVEVEKA
>SEQF1516_EDU86881.1 helix-turn-helix DNA-binding domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTVRDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELL
PGLEKQAPLRAAKVAPMQSFSLGKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELSSNSEQ
GQSVPLNTSTTTDPATTSTPPASVDTTATNTQTPVVTAPAPAVDPQQNAVVSPSQANVDTAATPAPTAATTPDGAAPLPT
DQAGVTTPVADPNALVMNFTADCWLEVTDATGKKLFSGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIR
TNQVARLTLNAEQSPAQ
>SEQF1516_EDU86882.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSLRLMLCAMPLMLTGCSTMSSVNWSAANPWNWFGSSTKVSEQGVGELTASTPLQEQAIADAVDGDYRLRSGMKTANGN
VVRFFEVMKGDNVAMVINGDQGTISRIDVLDSDIPADTGVKIGTPFSDLYSKAFGNCQKADGDDNRAVECKAEGSQHISY
QFSGEWSGPEGLMPSDDTLKNWKVSKIIWRR
>SEQF1516_EDU86883.1 ethanolamine utilization protein EutQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLITANDIREAHARGEQAMSVVLRASIITPEAREVADLLGFTITECDELIPVTASVPASVPADKTESQRIRETIIAQL
PEGQFTESLVAQLMEKVMKEKQSLEQGAMQPSFKSVTGKGGIKVIDGSSVKFGRFDGAQPHCVGLTDLVTGDDGSSMAAG
FMQWENAFFPWTLNYDEIDMVLEGELHVRHEGETMIAKAGDVMFIPKGSSIEFGTTSSVKFLYVAWPANWQSL
>SEQF1516_EDU86884.1 3-mercaptopyruvate sulfurtransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMR
ELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDV
LLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCGS
GVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPVEPLK
>SEQF1516_EDU86885.1 holo-(acyl-carrier-protein) synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAILGLGTDIVEIARIEAVIARSGERLARRVLSDNEWEIWKTHHQPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVF
NDELGKPRLRLWGEALKLAEKLGVANMHVTLADERHYACATVIIES
>SEQF1516_EDU86886.1 transcriptional regulator, RpiR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYLTKIRNAESEFTENEQKIADFLRANVSELKSVSSRKMAKQLGISQSSIVKFAQKLGAQGFTELRMALIGEYSASREK
TNATAQHLHSSITSDDSLEVIARKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGCDLSFKLMKI
GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSLADSPLRRLAHFTLDTVSGETEW
RSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIQRSSELTQRLK
>SEQF1516_EDU86887.1 hydrogenase-4 component A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRFVVAEPLWCTGCNTCLAACSDVHKTQGLQQHPRLALAKTSTLTAPVVCHHCEEAPCVQVCPVNAISQRDDAIQLNES
LCIGCKLCAVVCPFGAISASGSRPVNAPAQYVFQAEGSLKDGEENAPTQHALLRWEPGVQTVAVKCDLCDFLPEGPACVR
ACPNQALRLITDDSLQRQMKEKQRLAASWFANGREDPLSLTQEQR
>SEQF1516_EDU86888.1 ethanolamine ammonia-lyase, light chain [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDQKQIEEIVRSVMASMGQTAPAPSEAKCATTTCAAPVTSESCALDLGSAEAKVWIGVENPHRADVLTELRRSTVARVCT
GHAGPRPRTLALLRFLADHSRSKDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPD
VQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILGAKVVILLVGERPGLGQSESLSC
YAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVIVDLAKRMLEQKASGINMTR
>SEQF1516_EDU86889.1 arsenate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKQVKIYHNPRCSKSRETLNLLKENGVEPEVVLYLETPADAATLRDLLKMLGMNSARELMRQKEDLYKELNLADSSLSE
EALIQAMVDNPKLMERPIVVANGKARIGRPPEQVLEIVG
>SEQF1516_EDU86890.1 histidyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLPIVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTL
RPEGTAGCVRAGIEHGLLYNQEQRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEH
VTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQALLNDAPALGDYLDEESREHFAGL
CKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSLGSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVN
PEFKADPVVDIYLVASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEVANGTAVVK
DLRSGEQTAVAQDSVAAHLRTLLG
>SEQF1516_EDU86891.1 DNA repair protein RecO [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRSTLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALP
LSGITLYSGLYINELLSRVLEYETRFSELFFDYLHCIQSLAGVTGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDD
TMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLGGKPLKSRELFRQFMPKRTVKTH
YE
>SEQF1516_EDU86892.1 hypothetical protein ECH7EC4501_1282 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDFHDLHTLSPLRGSHKKNRRIIPPFFKAAILFSLTLVKMITV
>SEQF1516_EDU86893.1 putative cytochrome C-type biogenesis protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLNATYIKIRDKWWGLPLFLPSLILPIFAHINTFAHISSGEVFLFYLPLALMISMMMFFSWAALPGIALGIFVRKYAEL
GFYETLSLTANFIIIIILCWGGYRVFTPRRNNVSHGDTRLISQRIFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMP
FNLGTLINYQALLVGNLIGVPLCYFIIRVVRNPFYLRSYYSQLKQQVDVKVTKKEFALWLLALGALLLLLCMPLNEKSTI
FSTNYTLSLLLPLMMWGAMRYGYKLISLLWAVVLMISIHSYQNYIPIYPGYTTQLTITSSSYLVFSFIVNYMAVLATRQR
TVVRRIQRLAYVDPVVHLPNVRALNRALRDAPWSALCYLRIPGMEMLVKNYGIMLRIQYKQKLSHWLSPLLEPGEDVYQL
SGNDLALRLNTESHQERITALDSHLKQFRFFWDGMPMQPQIGVSYCYVRSPVNHIYLLLGELNTVAELSIVTNAPENMQR
RGAMYLQRELKDKVAMMNRLQQALEHNHFFLMAQPITGMRGDVYHEILLRMKGENDELIGPDSFLPVAHEFGLSSSIDMW
VIEHTLQFMAENRAKMPAHRFAINLSPTSVCQARFPVEVSQLLDKYQIEAWQLIFEVTESNALTNVKQAQITLQHLQELG
CQIAIDDFGTGYASYARLKNVNADLLKIDGSFIRNIVSNSLDYQIVASICHLARMKKMRVVAEYVENEEIREAVLSLGID
YMQGYLIGKPQPLIDTLNEIEPIRESACNKWGRQFFLCRASDAYMDSGVLSLQFSTASQPRLPSILAPFPDQAVPAHSD
>SEQF1516_EDU86894.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHAVDGTYIKAQQDKMVNSSLCKKSSVDTYFNVMEVNLIIYNDDVIMMN
>SEQF1516_EDU86895.1 sulfate/thiosulfate ABC transporter, periplasmic sulfate/thiosulfate-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVNLLKKNSLALVASLLLAGHVQATELLNSSYDVSRELFAALNPPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGL
KADVVTYNQVTDVQILHDKGKLIPADWQSRLPNNSSPFYSTMGFLVRKGNPKNIHDWNDLVRSDVKLIFPNPKTSGNARY
TYLAAWGAADKADGGDKAKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFESEVNNIRKQYEAQGFEVVIPKT
NILAEFPVAWVDKNVQANGTEKAAKAYLNWLYSPQAQTIITDYYYRVNNPEVMDKLKDKFPQTELFRVEDKFGSWPEVMK
THFTSGGELDKLLAAGRN
>SEQF1516_EDU86896.1 putative ethanolamine utilization protein EutL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPALDLIRPSVTAMRVIASVNADFARELKLPPHIRSLGLISADSDDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPT
AGEVLIMLGGPNPAEVRAGLDAMVAHIENGAAFQWANDAQDTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVAPPLEATY
GIDAALKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLEIARNPIQRA
>SEQF1516_EDU86897.1 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVASLRQRFGEHILAVEGNVTCYADYQRAVDQILTRSGK
LDCFIGNAGIWDHNASLVNTPAETLETGFHELFNVNVLGYLLGAKACAPALIAGEGSMIFTLSNAAWYPGGGGPLYTASK
HAATGLIRQLAYELAPKVRVNGVGPCGMASDLRGPQALGQSETSIMQSLTPEKIAAILPLQFFPQPADFTGPYVMLASRR
NNRALSGVMINADAGLAIRGIRHVAAGLDL
>SEQF1516_EDU86898.1 hydrogenase-4 component C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRQTLCDGYLVIFALAQAVILLMLTPLFTGISRQIRARMHSRRGPGIWQDYRDIHKLFKRQEVAPISSGLMFRLMPWVLI
SSMLVLAMALPLFITVSPFAGGGDLITLIYLLALFRFFFALSGLDTGSPFAGVGASRELTLGILVEPMLILSLLVLALIA
GSTHIEMISNTLATGWNSPLTTVLALLACGFACFIEMGKIPFDVAEAEQELQEGPLTEYSGAGLALAKWGLGLKQVVMAA
LFVALFLPFGCAQELSLACLLTSLVVTLLKVLLIFVLASIAENTLARGRFLLIHHVTWLGFSLAALAWVFWLTGL
>SEQF1516_EDU86899.1 putative inner membrane protein YfeZ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLFVIAGASREQGTALLNLFYPDHDNFWLGLIPGIPAVLAFLLSGRRATFPRTWRVLYFLLLLAQVVLLCWQPWLWLNGE
SVSGIGLALVVADIVALIWLLTNRRLRACFNEVKE
>SEQF1516_EDU86900.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENKELATGNGFLFRFVMQIFHFITFFLKNTKEPFTLQGYFL
>SEQF1516_EDU86901.1 alpha-2-macroglobulin domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSENASSAKLSAPERQKLAQQSAGKALTLLDLSEVQLDGA
ATLVLTFSIPLDPDQDFSRVIHVVDKKSGKVDGAWELSDNLKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDYEKTIT
TRDIQPSVGFASRGSLLPGKVVEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRNSLANWQSDKLLQMADLVYTGRF
DLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAGRYDYSNPATLFTLSDIGVSAHRYHNRLDIFTQSLENGAAQQGIE
VSLLNEKGQTLTQATSDAQGHVQLENDKNAALLLARKDGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFGPRDLYRPG
ETVILNGLLRDADGKALPNQPIKLDVIKPDGQVLRSVVSQPENGLYHFTWPLDSNAATGMWHIRANTGDNQYRMWDFHVE
DFMPERMALNLTGEKTPLTPNDEVKFSVVGYYLYGAPANGNTLQGQLFLRPLREAVSALPGFEFGDIAAENLSRTLDEVQ
LTLDDKGRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALPGIRPQFASKSVYDYRTDSTVKQPIV
DEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSEDEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGA
YRLEVKAPNEAVSSVRFWAGYSWQDNSDGSGAVRPDRVTLKLDKAGYRPGDTIKLHIAAPTAGKGYAMVESSEGPLWWQE
IDVPAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGDENRRLDLALETPAKMRPNQPLTVKIK
ASTKNGEKPKQVNVLVSAVDSGVLNITDYVTPDPWQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKP
PVNHVNIVAQQALPVTLNEQGEGSVTLPIGDFNGELRVMAQAWTADEFGSNESKVIVAAPVIAELNMPRFMASGDNSRLT
LDITNLTDKPQKLNVALTASGLLELVSDSPAAVELAPGVRTTLFIPVRALPGYGDGEIQATISGLALPGETVADQHKQWK
IGVRPAFPAQTVNYGTALQPGETWAIPADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLY
TNAAQLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDFLVRAGEQGYSVPTDAINRGN
ERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLARQQKAPLGALREIWEHRADAASGLPLLQLGVALKTMGDATRDE
EAIALALKTPRNSDERIWLGDYGSPLRDNALMLSLLEENKLLPDEQYSLLNTLSQQAFGERWLSTQESNALFLAARTIQD
LPGKWQAQTSFSAEPLTGEKAQNSNLNSDQLATLQVTNSGEQPLWLRVDASGYPQSAPLPANNVLQIERHILGTDGKSKS
LDSLRSGDLVLVWLQVKASNSVPDALVVDLLPAGLELENQNLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVA
AVAVDEYQPVTLVYLARAVTPGTYQVPQPMVESMYVPQWRATGAAEDLLIVRP
>SEQF1516_EDU86902.1 hypothetical protein ECH7EC4501_1367 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDCGIWKRPRICYAKCNKASEITGSRLPKMFQIAQAQAAMPRLR
>SEQF1516_EDU86903.1 stationary phase inducible protein CsiE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPTLAPPSVLSAPQRRCQILLTLFQPGLTATMATFSELNGVDDDIASLDISETGREILRYHQLTLTTGYDGSYRVEGTV
LNQRLCLFHWLRRGFRLCPSFITSQFTPALKSELKRRGIARNFYDDTNLQALVNLCSRRLQKRFESRDIHFLCLYLQYCL
LQHHAGITPQFNPLQRRWAESCLEFQVAQEIGRHWQRRALQPVPPDEPLFMALLFSMLRVPDPLRDAHQRDRQLRQSIKR
LVNHFRELGNVRFYDEQGLCDQLYTHLAQALNRSLFAIGIDNTLPEEFARLYPRLVRTTRAALAGFESEYGVHLSDEESG
LVAVIFGAWLMQENDLHEKQIILLTGNDSEREAQIEQQLRELTLLPLNIKHMSVKAFLQTGAPRGAALIIAPYTMPLPLF
SPPLIYTDLTLTTHQQEQIRKMLESA
>SEQF1516_EDU86904.1 lipoprotein, NlpB/DapX family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYSVHKSRLATVAGVSLVLLLAACSSDSRYKRQVSGDEAYLEAAPLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKAL
DIRPPAQPLALVSGARTQFTGDTASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGR
YQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAANAAQNRASTTMDVQSAADDTGLP
MLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNMAVTYKPLSDSDWQELGASDPGLASGDYKLQVGDLDNRSSLQFID
PKGHTLTQSQNDALVAVFQAAFSK
>SEQF1516_EDU86905.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLIVVLVAGYYGVDLTGLMTGQPVSQQQSTRSISPNEDEAA
KFTSVILATTEDTWGQQFEKMGKTYQQPKLVMYRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFA
QGYVIAHEVGHHVQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWGHSMQQQGVLETGDLEEALNAAQAIGD
DRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGDPAQCNTFGKSI
>SEQF1516_EDU86906.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKMNHDVSLFLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEFRG
RGIANALLNRLEKKLIARGCPKIQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY
>SEQF1516_EDU86907.1 sseB protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSETKNELEDLLEKAATEPAHRPAFFRTLLESTVWVPGTAAQGEAVVEDSALDLQHWEKEDGTSVIPFFTSLEALQQAVE
DEQAFVVMPVRTLFEMTLGETLFLNAKLPTGKEFMPREISLLIGEEGNPLSSQEILEGGESLILSEVAEPPAQMIDSLTT
LFKTIKPVKRAFICSIKENEEAQPNLLIGIEADGDIEEIIQVAGSVATDTLPGDEPIDICQVKKGEKGISHFITEHIAPF
YERRWGGFLRDFKQNRII
>SEQF1516_EDU86908.1 sensor histidine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQAALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDD
PTLAKVYQSQRKRYSEMLDAHAGVLPDDKLYQALRQDLNNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSR
GQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLGNSVSFSGPSELRSVGQRILWLS
ERLSWLESQRHQFLRHLSHELKTPLASMREGTELLADQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAV
ELDNVELAPLVETVVSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSLHGARVYID
VINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQGELYLVDESGQDVCFRIELPSSKNTK
>SEQF1516_EDU86909.1 FeS assembly protein IscX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGLKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICDLEDFDDDPQASNEKILEAILLVWLDEAE
>SEQF1516_EDU86910.1 ethanolamine utilization cobalamin adenosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKDFITEAWLRANHTLSEGAEIHLPADSRLTPSARELLESRHLRIKFIDEQGRLFVDDEQQQPQPVHGLTSSDEHPQACC
ELCRQPVAKKPDTLTHLSAEKMVAKSDPRLGFRAVLDSTIALAVWLQIELAEPLGCQAIVGLSDEDLHRLSHQPLRYLGH
DHLVPEASHGRDAALLNLLRTKVREAETVAAQVFITRSFEVLRPDILQALNRLSSTVYVMMILSVTKQPLTVKQIQQRLG
ETQ
>SEQF1516_EDU86911.1 putative inner membrane protein YphA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSLRYFDFGAARPVLLLIARIAVVLIFIIFGFPKMMGFDGTVQYMASLGAPMPMLAAIIAVVMEVPAAILIVLGFFTRP
LAVLFIFYTLGTAVIGHHYWDMTGDAVGPNMINFWKNVSIAGAFLLLAITGPGAISLDRR
>SEQF1516_EDU86912.1 protein aegA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRFIMANSQQCLGCHACEIACVMAHNDEQHVLSQHHFHPRITVIKHQQQRSAVTCHHCEDAPCARSCPNGAISHVDDSI
QVNQQKCIGCKSCVVACPFGTMQIVLTPVAAGKVKATAHKCDLCAGRENGPACVENCPADALQLVTDAALSGMAKSRRLR
TARQEHQPWHASTAAQEMPVMSKVEQMQATPARGEPDKLAIEARKTGFDEIYLPFRADQAQREASRCLKCGEHSVCEWTC
PLHNHIPQWIELVKAGNIDAAVELSHLTNTLPEITGRVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDL
SHVTKVDKRVAIIGAGPAGLACADVLIRNGVAVTVYDRHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGIHFELNCEV
GKDVSLDSLLEQYDAVFVGVGTYRSMKAGLPNEDAPGVYDALPFLIANTKQVMGLEELPEEPFINTAGLNVVVLGGGDTA
MDCVRTALRHGASNVTCAYRRDEANMPGSKKEVKNAREEGANFEFNVQPVALELNEQGHVCGIRFLRTRLGEPDAQGRRR
PVPVEGSEFVMPADAVIMAFGFNPHGMPWLESHGVTVDKWGRIIADVESQYRYQTTNPKIFAGGDAVRGADLVVTAMAEG
RHAAQGIIDWLGVKSVKSH
>SEQF1516_EDU86913.1 putative sugar ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTATEAVPVAKVVAGNKRYPGVVALDNVNFTLNKGEVRALLGKNGAGKSTLIRMLTGSERPDSGEIWIGETRLEGDEAT
LTRRAAELGVRAVYQELSLVEGLTVAENLCLGQWPRRNGMIDYLQMAQDAQRCLQALGVDVSPEQLVSTLSPAHKQLVEI
ARVMKGEPRVVILDEPTSSLASAEVELVIRAVKKMSALGVAVIYVSHRMEEIRRIASSATVMRDGQVAGDVMLENTSTHH
IVSLMLGRDHVDIAPVAPQEIVDQAVLEVRALRHKPKLEDISFTLRRGEVLGIAGLLGAGRSELLKAIVGLETYEQGEIV
INGEKITRPDYGDMLKRGIGYTPENRKEAGIIPWLGVDENTVLTNRQKISANGVLQWSTIRRLTEEVMQRMTVKAASSET
PIGTLSGGNQQKVVIGRWVYAASQILLLDEPTRGVDIEAKQQIYRIVRELAAEGKSVVFISSEVEELPLVCDRILLLQHG
TFSQEFHAPVNVDELMSAILSVH
>SEQF1516_EDU86914.1 ArsC family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTLYGIKNCDTIKKARRWLEANNIDYRFHDYRVDGLDSELLNGFINELGWEALLNTRGTTWRKLDETTRNIITDAASAA
ALMTEMPAIIKRPLLCAPGKPMLLGFSDSSYQKFFHEV
>SEQF1516_EDU86915.1 transketolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYD
LPLEELKNFRQLHSKTPGHPEIGYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGHDPQAVKEAILEAQSVKDKPSLI
ICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKLGWHHPPFEIPKDIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQL
AEEFTRRMSGGLPKDWEKTTQKYINELQANPAKIATRKASQNTLNAYGPMLPELLGGSADLAPSNLTIWKGSVSLKEDPA
GNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALMKARQIMVYTHDSIGLGEDGPTHQAVEQLAS
LRLTPNFSTWRPCDQVEAAVGWKLAVERHNGPTALILSRQNLAQVERTPDQVKEIARGGYVLKDSGGKPDIILIATGSEM
EITLQAAEKLAGEGRNVRVVSLPSTDIFDAQDEEYRESVLPSNVAARVAVEAGIADYWYKYVGLKGAIVGMTGYGESAPA
DKLFPFFGFTAENIVAKAHKVLGVKGA
>SEQF1516_EDU86916.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKIIPGATGYFNKTLNSNQFDNEDAIKGKVNSIYGKSIDYSTMRHRDIIIAKIDLFIQRITHNLWTAREKNVTLIKQIN
DLKMCVNEYIGDCTDEELNDREFIASVVDRAIFHFAINSICNPEDNKDATLIERCTFDVETKNGLPSTVQLFYEESKDNE
PLANIHLQAIGSGFLTFVNACQEHDDNSLKLFASLLISLSYSSVYSDFAGRVNINEYNDNYLKAQFEELSQRDMKKYLGE
MKRLADGGEMNFDGYLDKMSHLVNEGTLAPDILSKMRDAAPKLIDFAKSFDPNSKEKIKIYTGTSKLIYDLFGVKSEK
>SEQF1516_EDU86917.1 maltose/maltodextrin ABC transporter, ATP-binding protein MalK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMV
FQSYALYPHLSVAENMSFGLKLAGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP
LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKPLELYHYPADRFVAGFIGSPKMN
FLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQVGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQI
PSIRQNLVYRQNDVVLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGV
>SEQF1516_EDU86918.1 phosphonate ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTIICVEQLSKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAGSHIELLGRTVQREGRLARD
IRKSRANTGYIFQQFNLVNRLSVLENVLIGALGSTPFWRTCFSWFTREQKQRALQALTRVGMAHFAYQRVSTLSGGQQQR
VAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDGSSQQF
DNERFDHLYRSINRVEENAKAA
>SEQF1516_EDU86919.1 ribosomal large subunit pseudouridine synthase F [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGDQVKPGDVVKVNGQLIEPREAEDLVLIALNKPVGIVS
TTEDGERDNIVDFVNHSKRVFPIGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIL
GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPLGEWRDLTDDELIDLFKLIENSS
SEAKPKAKAKPKTAGIKRPVVKMEKTAEKGGRPASNGKRFTSPGRKKKGR
>SEQF1516_EDU86920.1 fumarate reductase, iron-sulfur protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYIKDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKT
FLRDYTDGMKVEALANFPIERDLVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKHVDPAAAIQQGKVESSKDFLIAT
LKPR
>SEQF1516_EDU86921.1 homoserine O-succinyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLMPKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNT
PAEHLNNFYCNFEDIQEQNFDGLIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTR
TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGDAYLFASKDKRIAFVTGHPEYDA
QTLAQEYFRDVEAGLDPEVPYNYFPHNDPQNKPRASWRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD
>SEQF1516_EDU86922.1 malate synthase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEQATTTDELAFIRPYGEQEKQILTAEAVEFLTELVTHFTPQRNKLLAARIQQQQDIDNGTLPDFISETASIRDADWKI
RGIPADLEDRRVEITGSVERKMVINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNP
AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQSWQEAAWWSEVFSYAEDRFNLPR
GTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGRWDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCH
KRGAFAMGGMAAFIPSKDEEHNNQVLNKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEVMREQDAPI
TADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAATAEISRTSIWQWIHHQKTLSNGKPVTKALFR
QMLGEEMKVIASELGEERFSQGRFDDAARLMEQITTSDELIDFLTLPGYRLLA
>SEQF1516_EDU86923.1 periplasmic binding protein/LacI transcriptional regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTALCAGALLAAAPFAQAKELKSIGVTVGDLANPFFVQITKGAELEARKLAGDNVKVTLVSSGYDLGQQVSQIDNFIAAN
VDMIILNAADSKGIGPAVKRAKDAGIVVVAVDVAAEGADATITSDNTQAGEMACKYITDRLKGKGNVVIINGPPVSAVQN
RVEGCQTEFKRHPDIKVLSDNQNAKGSREGGLEVMTGLLAANPKIDGVFAINDPTAIGADLAAKQAQRNEFFIVGVDGSP
DAEEALKRENSLFVATPAQDPQVMAAKAVEIGYDILQGKPAPKEPVLIPVTMIDKNNVGNYKGWTVK
>SEQF1516_EDU86924.1 aspartate ammonia-lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDIPEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAAC
DEVLNNGKCMDQFPVDVYQGGAGTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSL
IKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNIQRTAELLLEVNLGATAIGTGLN
TPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGAYVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAG
SSIMPAKVNPVVPEVVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCINGITANKEV
CEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTEAELDDIFSVQNLMHPAYKAKRYTDESEQ
>SEQF1516_EDU86925.1 transcriptional regulator AdiY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRICSDQPCIVLLTEKDVWIRVNGKEPISLKANHMALLNCENNIIDVSSLNNTLVAHISHDIIKDYLRFLNKDLSQIPVW
QRSATPILTLPCLTPDVFRVAAQHSMMPAETESEKERTRALLFTVLSRFLDSKKFLSLMMYMLRNCVSDSVYQIIESDIH
KDWNLSMVASCLCLSPSLLKKKLKSENTSYSQIITTCRMRYAVNELMMDGKNISQVSQSCGYNSTSYFISVFKDFYGMTP
LHYVSQHRERTVA
>SEQF1516_EDU86926.1 quinone oxidoreductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATRIEFHKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAAGIVSKVGSGVKHIK
AGDRVVYAQSALGAYSSVHNINADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQW
AKALGAKLIGTVGTAQKAQSALKAGAWQVINYREENLVERLKEITGGKKVRVVYDSVGRDTWERSLDCLQRRGLMVSFGN
SSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREELTEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILESRATQ
GSSLLIP
>SEQF1516_EDU86927.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDQALLDGGYRCYTGEKIDVYFNTAICQHSGNCVRGNGKLFNLKRKPWIMPDEVDVATVVKVIDTCPSGALKYRHK
>SEQF1516_EDU86928.1 hypothetical protein ECH7EC4501_0213 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVFAITGTFILNGLLSHQERSSPPVCDLVCKGENILSSCPSISVAGLVA
>SEQF1516_EDU86929.1 mechanosensitive ion channel family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLIITFLMAWCLSWGAYAATAPDSKQITQELEQAKAAKPAQPEVVEALQSALNALEERKGSLERIKQYQEVIDNYPKLS
ATLRAQLNNMRDEPRSVSPGMSTDALNQEILQVSSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLG
TLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSELAEKESQQLDAYLQALRNQLNSQRQLEAERA
LESTELLAENSADLPKDIVAQFKINRELSAALNQQAQRMDLVASQQRQAASQTLQVRQALNTLREQSQWLGSSNLLGEAL
RAQVARLPEMPKPQQLDTEMAQLRVQRLRYEDLLNKQPLLRQIHQADGQPLTAEQNRILEAQLRTQRELLNSLLQGGDTL
LLELTKLKVSNGQLEDALKEVNEATHRYLFWTSDVRPMTIAWPLEIAQDLRRLISLDTFSQLGKASVMMLTSKETILPLF
GALILVGCSIYSRRYFTRFLERSAAKVGKVTQDHFWLTLRTLFWSILVASPLPVLWMTLGYGLREAWPYPLAVAIGDGVT
ATVPLLWVVMICATFARPNGLFIAHFGWPRERVSRGMRYYLMSIGLIVPLIMALMMFDNLDDREFSGSLGRLCFILICGA
LAVVTLSLKKAGIPLYLNKEGSGDNITNHMLWNMMIGAPLVAILASAVGYLATAQALLARLETSVAIWFLLLVVYHVIRR
WMLIQRRRLAFDRAKHRRAEMLAQRARGEEEAHHHSSPEGAIEVDESEVDLDAISAQSLRLVRSILMLIALLSVIVLWSE
IHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLELAILQHLDLTPGTGYAITTITKYL
LMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFGLQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTIS
DWDRKEIIVPNKAFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTEILLTAARRCSLVIDNPAPEVFLVDLQQGIQIF
ELRIYAAEMGHRMPLRHEIHQLILAGFHAHGIDMPFPPFQMRLESLNGKQTGRTLTSAGKGRQAGSL
>SEQF1516_EDU86930.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRHSTLFLFTLLTLTTVPAQADIIDDTIGNIQQAINDASNPDRGRDYEDSRDDGWQREVSDDRRRQYDDRRRQFEDRRR
QLDDRQHQLNQERRQLEDEERRMEDEYGQ
>SEQF1516_EDU86931.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKRHLLSLLALGISTACYGETYPAPIGPSQSDFGGVGLLQTPTARMAREGELSLNYRDNDQYRYYSASVQLFPWLETTL
RYTDVRTRQYSSVEAFSGDQTYKDKAFDLKLRLWEESYWLPQVAVGARDIGGTGLFDAEYLVASKAWGPFDFTLGLGWGY
LGTSGNVKNPLCSASDKYCYRDNSYKQAGSIDGSQMFHGPASLFGGVEYQTPWQPLRLKLEYEGNNYQQDFAGKLEQKSK
FNVGAIYRVTDWADVNLSYERANTFMFGVTLRTNFNDLRPSYNDNARPQYQPQPQDAILQHSVVANQLTLLKYNAGLADP
QIQAKGDTLYVTGEQVKYRDSREGIVRANRIVMNDLPDGIKTIRVTENRLNMPQVTTETDVASLKNHLAGEPLGHETKLA
QKRVEPVVPKSTEQGWYIDKSRFDFHIDPVLNQSVGGPENFYMYQLGVMGTADLWLTDHLLTTGSLFANLANNYDKFNYT
NPPQDSHLPRVRTHVREYVQNDVYVNNLQANYFQHLGNGFYGQVYGGYLETMFGGAGAEVLYRPLDSNWAFGLDANYVKQ
RDWRSAKDMMKFTDYSVKTGHLTAYWTPSFAQDVLVKASVGQYLAGDKGGTLEIAKRFDSGVVVGGYATITNVSKEEYGE
GDFTKGVYVSVPLDLFSSGPTRSRAAIGWTPLTRDGGQQLGRKFQLYDMTSDRSVNFR
>SEQF1516_EDU86932.1 transcriptional activator CadC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHSGEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLK
DNDEDSPVYIATVPKRGYKLMVPVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFW
VWFFFLLSLGICVALVAFSSLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLSYAIGVGDLVATSLNTFSTFMVH
DKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSIKLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQ
RMQETLQQILPHRGALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPLDEKQLAAL
NTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSWLNYVLLGKVYEMKGMNREAADAYLTAFNLR
PGANTLYWIENGIFQTSVPYVVPYLDKFLASE
>SEQF1516_EDU86933.1 phosphonate ABC transporter, periplasmic phosphonate-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAKIIASLAFTSMFSLSTLLSPAHAEEQEKALNFGIISTESQQNLKPQWTPFLQDMEKKLGVKVNAFFAPDYAGIIQGM
RFNKVDIAWYGNLSAMEAVDRANGQVFAQTVAADGSPGYWSVLIVNKDSPINNLNDLLAKRKDLTFGNGDPNSTSGFLVP
GYYVFSKNNISASDFKRTVNAGHETNALAVANKQVDVATNNTENLDKLKTSAPEKLKELKVIWKSPLIPGDPIVWRKNLS
ETTKDKIYDFFMNYGKTPEEKAVLERLGWAPFRASSDLQLVPIRQLALFKEMQSVKGNKGLNEQDKLAKTTEIQAQLDDL
DRLNNALSAMSSVSKAMQ
>SEQF1516_EDU86934.1 KamA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAGRNAKKLFALRVPRSFIDRMEKGNPDDPLLRQVLTSQ
DEFVVAPGFSTDPLEEQHSVVPGLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTALEYVAAHPELDEM
IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITDALVERFSHSTLQILLVNHINHANEIDETFRQAM
AKLRRAGVTLLNQSVLLRGVNDNAQTLANLSNALFDAGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVP
KLAREIGGEPSKTPLDLQLRQQ
>SEQF1516_EDU86935.1 phosphate-starvation-inducible E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLADVLFAPEQASKYELVEGLVVYFLYFEFIALIVKYFQS
GFHFPLRYFVYIGITAIVRLIIVDHKSPLDVLIYSAAILLLVVTLWLCNSKRLKRE
>SEQF1516_EDU86936.1 lysyl-tRNA synthetase LysU [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDHTSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIM
GKASFVTLQDVGGRIQLYVARDSLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGL
QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGASARPFITHHNALDLDMYLRIAP
ELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDF
GKPFEKLTMREAIKKYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITEYPAEVSPL
ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAGDDEAMFYDEDYVTALEYGLPPTAGLGIGID
RMIMLFTNSHTIRDVILFPAMRPQK
>SEQF1516_EDU86937.1 ShET2 enterotoxin, N- region family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITHIPRSSFSANINNTAQTNEHQTLSELFYKELEDKFSGKELATPLLKSFSENCRHNGRHIFSNKDFVIKFSISVLQAD
KKEITIINKNENTTLTQTIAPIFEEYLMEILPQRSDALDKKELNLNSDRKEKEFPRVKLNGQCYFPGRPQNRIVCRHIAA
QYINDIYQNVDYKPHQDDYSSAEKFLTHFNKKCKNQTLALISSRPEGRCVAACGDFGLVMKAYFDKMESNDLSVMAAILL
VDNHALTVRLRIKNTTEGCIHYVVSVYDPNVTNDKIRIMSESKEDIKHYSLMDFMNVDYSLLKWSNDHVINQSVAIIPAL
PKEQLLMLKGTVDEITPPLSPATMNLLMAIGQNHQLKQLMIQLQKMPELHRTEMLTAYNSINLPGLYLAINYGNADIVET
IFNSLSEPGYEGLLSKKNLMHILEAKDKNGFSGLFLAISRKDKNVVTSILNALPKLAATHHLDNEQVYKFLSAKNSTSSH
VLYHVMANGDADMLKIVLDALSLLIRTCHLTKEQVLDLLKAKDFYGCPGLYLAMQNGHSDIVKVILEALPSLAQEINISA
SDIVDLLTAKSLARDTGLFMAMQRGHMNVINTIFNALPTLFNTFKFDKKNMKPLLLANNSNEYPGLFSAIQHKQQNVVEM
VYLALSDHARLFGFTAEDIMDFWQHKAPQKYSAFELACELGHRVIAELIFNTLNKMAESFGFTDNPRYIAEKNYMEALLK
KASPHTVR
>SEQF1516_EDU86938.1 suppressor of F exclusion of phage T7 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLII
AGLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDDRDRLDHKDDRQD
>SEQF1516_EDU86939.1 entericidin B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAATKAQQ
>SEQF1516_EDU86940.1 aromatic-amino-acid transaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIPQLKAVAEAEARLNAVPHGASLYLPMEGLNSYRHAIA
PLLFGADHPVLQQQRVATIQTLGGSGALKVGADFLKRYFPESGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRF
NDLLAMLKTLPARSIVLLHPCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGFGAGMEEDAYAIRAIASAGLPAL
VSNSFSKIFSLYGERVGGLSVLCEDAEAAGRVLGQLKATVRRNYSSPPNFGAQVVAAVLNDEALKASWLAEVEEMRTRIL
AMRQELVKVLSTEMPERNFDYLLNQRGMFSYTGLSAAQVDRLREEFGVYLIASGRMCVAGLNTANVQRVAKAFAAVM
>SEQF1516_EDU86941.1 CsbD family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKDEAGGNWKQFKGKVKEQWGKLTDDDMTIIEGKRDQLVGKIQERYGYQKDQAEKEVVDWETRNEYRW
>SEQF1516_EDU86942.1 thiol:disulfide interchange protein DsbD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPVDQAFAFDFQQNQHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLP
QGVWHEDEFYGKSEIYRDRLTLPVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAASQPVSVPQQEQPT
AQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMALTYTALGLVVAAAGLQFQAALQ
HPYVLIGLTIVFTLLAMSMFGLLTLQLPSSLQTRLTLMSNRQQGGSPGGVFIMGTIAGLICSPCTTAPLSAILLYIAQSG
NMWLGGGTLYLYALGMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDVWGLRLWSALGVAFFGW
AFITSLQAKRGWMRVVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNFTQIKTVDELNQALVEAKGKPVMLDLYADWC
VACKEFEKYTFSDPQVQKALADTVLLQANVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHL
RDRQP
>SEQF1516_EDU86943.1 phosphonates metabolism transcriptional regulator PhnF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHLSTHPTSYPTRYQEIAAKLEQELRQHYRCGDYLPAEQQLAARFEVNRHTLRRAIDQLVEKGWVQRRQGVGVLVLMRPF
DYPLNAQARFSQNLLDQGSHPTSEKLLSVLRPASGHVADALGITEGENVIHLRTLRRVNGIALCLIDHYFADLTLWPTLQ
RFDSGSLHDFLREQTGIALRRSQTRISARRAQAKECQRLEIPNMSPLLCVRTLNHRDGESSPAEYSVSLTRADMIEFTME
H
>SEQF1516_EDU86944.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHVKYLAGIVGAALLMAGCSSSNELSAAGQSVRIVDEQPGAECQLIGTATGKQSNWLSGQHGEEGGSMRGAANDLRNQAA
AMGGNVIYGISSPSQGMLSSFVPTDSQIIGQVYKCPN
>SEQF1516_EDU86945.1 replicative DNA helicase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLDNERWDDVAERVVADDFYTRPHRHIFTEMARLQESGS
PIDLITLAESLERQGQLDSVGGFAYLAELSKNTPSAANISSYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL
AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKTAGLQPSDLIIVAARPSMGKTTF
AMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASLSRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTP
TEVRSRARRIAREHGGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQRADKRPVNS
DLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVRLTFNGQWSRFDNYAGPQYDDE
>SEQF1516_EDU86946.1 4-hydroxybenzoate polyprenyl transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVPQLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKR
TANRPLPSGAVTEKEARALFVVLVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGILQIGVLALMAIIGELNGLGWGYY
WSILVAGALFVYQQKLIANREREACFKAFMNNNYVGLVLFLGLAMSYWHF
>SEQF1516_EDU86947.1 chaperonin GroS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVGNGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDN
EEVLIMSESDILAIVEA
>SEQF1516_EDU86948.1 cytochrome c nitrite reductase, pentaheme subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVLRSLLTAGVLASGLLWSLNGITATPAAQASDDRYEVTQQRNPDAACLDCHKPDTEGMHGKHASVINPNNKLPVTCTN
CHGQPSPQHREGVKDVMRFNEPMYKVGEQNSVCMSCHLPEQLQKAFWPHDVHVTKVACASCHSLHPQQDTMQTLSDKGRI
KICVDCHSDQRTNPNFNPASVPLLKEQP
>SEQF1516_EDU86949.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSNGSSEAKTLTGAEHLIDLVGQPRLANSWWPGAVISEELATAAALRQQQALLTRLAEQGADSSADDAAAINALRQQIQ
ALKVTGRQKINLDPDIVRVAERANPPLQGNYTLWVGPPPSTVTLFGLISRPGNQPFTPGRDVASYLSGQSLLGGADRSYA
WVVYPDGRTQKAPVAYWNKRHVEPMPGSIIYVGLADSVWSEMPDALNADILQTLTQRIPQ
>SEQF1516_EDU86950.1 acetate operon repressor IclR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVAPIPAKRGRKPAVATAPATGQVQSLTRGLKLLEWIAESNGSVALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELG
HWAIGAHAFMVGSSFLQSRNLLAIVHPILRNLMEESGETVNMAVLDQSDHEAIIIDQVQCTHLMRMSAPIGGKLPMHASG
AGKAFLAQLSEEQVTKLLHRKGLHAYTHATLVSPVHLKEDLAQTRKRGYSFDDEEHALGLRCLAACIFDEHREPFAAISI
SGPISRITDDRVTEFGAMVIKAAKEVTLAYGGMR
>SEQF1516_EDU86951.1 entericidin A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS
>SEQF1516_EDU86952.1 integral membrane sensor hybrid histidine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAHPGRHFFASARGRLLLLNLLVVAVTLMVSGVAVMGFRHASQMQELVQQQTVDDMTGSLNLARDTANVATAAVRLSQVV
GALEYKGEAERLQETQRALKSSLAQLANAPLAQQEAGLVTRIITRSNELQTSVGGMLERGQRRHLERNALLSSLYQNLSY
LRHLQKVTHAQDDILLNEMNRLIVAAIATPAPQAIIHQLVGVMSALPTHSDTPLVNTLLNDFNDFNDEMRKLAPLSAALE
QSDLAISWYMFHIKALVAILNGDINRYAEQVATLSGQRVAQSYQDLRSGERVIMIFALLAVVITAFAGWYIYRNLGTNLT
AISRAMSRLAHGEADVTFPALQRRDELGELARAFNVFARNTASLERTSRLLKEKTTQMEIAQTERQGLEEALLHSQKLKA
VGQLTGGLAHDFNNLLAVIIGSLELVNPDSPDAPRIQRALQAAERGALLTQRLLAFSRKQSLHPQAVELKTLLEELSELM
RHSLPATLALEIEAQSPAWPAWIDISQLENAIINLVMNARDAMEGQTGIIKIRTWNQRVTRSSGQRQDMVALEVIDHGCG
MSQAVKSQVFEPFFTTKQTGSGSGLGLSMVYGFVRQSGGRVEIESAPGQGTTVRLQLPRALTAAKNLSPAAVEQASVSGD
KLVLVLEDEAAVRQTICEQLHLLGYLTLEASSGEQALDLLAASAEIDIFISDLMLPGGMSGAEVVNAARKLYPHLTLLLI
SGQDLRPSHNPALPDVALLRKPFTRAQLAQALGQEN
>SEQF1516_EDU86953.1 biodegradative arginine decarboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDGFAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKL
HERQQNVPVFLLGDREKALAAMDRDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAA
PGHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVFGADRSWSVVVGTSGSNRTIMQ
ACMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSRNRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVT
NCTYDGVCYNAKEAQDLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLNALSQASYIHV
REGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEVIDEAVDFRQAMARLYKEFAADGSWFFKPW
NKEVVTDPQTGKTYDFADAPTKLLTTVQDCWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALV
TAWLGRHGIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKRHYDANTPLAQVMPELVEQYPDTYANMGIHDLGDTMF
AWLKENNPGARLNEAYSGLPVAEITPREAYNAIVDNNVELVSIENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVS
YLRSLQSWDHHFPGFEHETEGTEIIDGIYHVMCVKA
>SEQF1516_EDU86954.1 single-stranded DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYI
EGQLRTRKWTDQSGQDRYTTEVVVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSA
PAAPSNEPPMDFDDDIPF
>SEQF1516_EDU86955.1 LexA repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAEEHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVG
RVAAGEPLLAQQHIEGHYQVDPSLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKK
QGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL
>SEQF1516_EDU86956.1 hypothetical protein ECH7EC4501_0323 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYDMNFSSIVADEYGIPRQLNENSFAITTSLAASEIEDLIRLKCLDLPDIDFDLNIMTVDDYFRQFYK
>SEQF1516_EDU86957.1 probable fructose-bisphosphate aldolase 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLISLAEGLAHAREHHYSLGAFNVLDSHFLRALFAAARQERSPFIINIAEVHFKYISLDSLVETVKFEAARHDIPVVLN
LDHGLHFESVVQALRLGFSSVMFDGSTLGYEENVRQTREVVKMCHAVGVSVEAELGAVGGDEGGALYGHADESLFTDPQL
ARDFVDRTGIDALAVAIGNAHGKYRGEPKLDFPRLDAIRQQAAIPLVLHGGSGISDADFRRAIELGIHKINFYTGMSQAA
LAAVEARMAHRQPMYDEFAELLLAVEAAISDTVAQQMRIFGSAGQA
>SEQF1516_EDU86958.1 phosphonate metabolism protein PhnM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIINNVKLVLENEVVNGSLEMQDGEIRAFAESQSRLPEAMDGEGGWLLPGLIELHTDNLDKFFTPRPKVDWPAHSAMSSH
DALMVASGITTVLDAVAIGDVRDGGDRLENLEKMINAIEETQKRGVNRAEHRLHLRCELPHNTTLPLFEKLVQREPVTLV
SLMDHSPGQRQFANREKYREYYQGKYSLTDAQMQQYEEEQLALAARWSQPNRESIAAMCRARQIALASHDDATHAHVAES
HQLGSVIAEFPTTFEAAEASRKHGMNVLMGAPNIVRGGSHSGNVAASELAQLGLLDILSSDYYPASLLDAAFRVADDQSN
RFTLPQAVKLVTKNPAQALNLQDRGVIGEGKRADLVLAHRKGNHIHIDHVWRQGKRVF
>SEQF1516_EDU86959.1 maltose/maltodextrin ABC transporter, permease protein MalF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAITTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVL
FPLVCTIAIAFTNYSSTNQLTFERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGREQKLQLK
ETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQIGFYQSI
TADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKPFLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVL
LILPYAVPSFISILIFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLLKAIPDDLY
EASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNGGPDRLGTTTPAGYTDLLVNYTYRIAFEGGG
GQDFGLAAAIATLIFLLVGALAIVNLKATRMKFD
>SEQF1516_EDU86960.1 melibiose carrier protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTATRYPMSISMTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLVGTLFLVARIWDAINDPIMGWIVNATRSR
WGKFKPWILIGTLANSVILFLLFSAHLFEGTTQIAFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPYPRFFA
SLAGFVTAGVTLPFVNYVGGGDRGFGFQMFTLVLIAFFIVSTIITLRNVHEVFSSDNQPSAEGSHLTLKAIVALIYKNDQ
LSCLLGMALAYNVASNIITGFAIYYFSYVIGDADLFPYYLSYAGAANLVTLVFFPRLVKSLSRRILWAGASILPVLSCGV
LLLMALMSYHNVVLIVIAGILLNVGTALFWVLQVIMVADTVDYGEYKLHVRCESIAYSVQTMVVKGGSAFAAFFIAVVLG
MIGYVPNVEQSTQALLGMQFIMIALPTLFFMVTLILYFRFYRLNGDTLRRIQIHLLDKYRKIPPEPVHADIPVGAVSDVK
A
>SEQF1516_EDU86961.1 hypothetical protein ECH7EC4501_0269 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPHFIWGHSLILRALFIQNSDEKQAVVSFDVTKRNTA
>SEQF1516_EDU86962.1 fumarate reductase, D subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGLFPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGL
HRMHHAMHDLKIHVPAGKWVFYGLAAILTVVTLIGVVTI
>SEQF1516_EDU86963.1 lysine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLKLIENNARLCGVIFDWDKYNLELCEEISKMNENLPLY
AFANTYSTLDVSLNDLRLQISFFEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
SPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTNGTSTANKIVGMYSAPAGSTILI
DRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIPQSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKK
TLDVKSIHFDSAWVPYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEAYMMHTTTS
PHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWFFDVWQPDHIDTTECWPLRSDSTWHGFKNID
NEHMYLDPIKVTLLTPGMEKDGTMSDFGIPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAF
DLNLRVKNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAFQKELHGMTEEVYLDEM
VGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEIGAHYPGFETDIHGAYRQADGRYTVKVLKEESKK
>SEQF1516_EDU86964.1 isocitrate dehydrogenase kinase/phosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQQAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAEFLL
RVKEHYTRLLPDYPRFEIAESFFNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDL
PLRLHWQNKSRDIHYIIRHLTETLGPENLSKSHLQVANELFYRNKAAWLVGKLITPSGTLPFLLPIHQTDDGELFIDTCL
TTTAEASIVFGFARSYFMVYAPLPAALVEWLREILPGKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRG
MVMLVFTLPGFDRVFKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMELLLQEAAEK
ITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAAANIFPGDMLFKNFGVTRHGRVVFYDYDEIC
YMTEVNFRDIPPPRYPEDELASEPWYSVSPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDV
YAYRRRQRFSVRYGEMLF
>SEQF1516_EDU86965.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKTLLDGPGRVLESVYPRFLVDLAQGDDARLPQAHQQQFRERLMQELLARVQLQTWTNGGMLNAPLSLRLTLVEKLASM
LDPGHLALTQIAQHLALLQKMDHRQHSAFPELPQQIAALYEWFSARCRWKEKALTQRGLLVQAGEQSEQIFTRWRAGAYN
AWSLPGRCFIVLEELRWGAFGDACRLGSPQAVALLLGDLRVKATQHLAESINAAPTTRHYYHQWFASSTVPTGGDHADFL
SWLGKWTTADKQPVCWSVTQRWQTVALGMPRLCSAQRLAGAMLEEIFSVNLV
>SEQF1516_EDU86966.1 glucose-6-phosphate isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSATFDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIK
SMFSGEKINRTENRAVLHVALRNRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDL
GPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTNAHSARDWFLKAAGDEKHVAKHF
AALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSAIGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALI
GIWYNNFFGAETEAILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLIHQGTKMVP
CDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKDPATLDYVVPFKVFEGNRPTNSILLREITPF
SLGALIALYEHKIFTQGVILNIFTFDQWGVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG
>SEQF1516_EDU86967.1 alkylphosphonate utilization operon protein PhnA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFLSNENDRRLKSAVPPTNSGILCIIAAFFGNLPFFGAFALLTFEEIHMSLPHCPKCNSEYTYEDNGMYICPECAYEWN
DAEPAQESDELIVKDANGNLLADGDSVTIIKDLKVKGSSSMLKIGTKVKNIRLVEGDHNIDCKIDGFGPMKLKSEFVKKN
>SEQF1516_EDU86968.1 PfkB domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMERKGIIAAGNMLVDHVHQIIQWPERGWLAEITHSERSTGGAPLNVLLTLAKMRTGLPLQAVGLIGQDSDGDYIMAMLE
QYHVNRQHVQRTTFAPTSMSQVMTDPSGQRTFFHSPGANRLLDLPAFDQLDNTMKIFHLGYLLLLDSLDMPDDVYGTRSA
RLLAQMRDTGFETSLDLVSRKGDPRYQPLVLPALRHLDYLVINELEAGEFSGLEIRLPNGEPHIAHIAAAARELLDAGVR
QRVVIHYPEGAWGETPEQGGVWIPSQKLEQREIIGSVGAGDAFCAGFLYGCHERWTLTESIKLAHACARASLLCANAIDG
AKTLEELQTEMSD
>SEQF1516_EDU86969.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRYNGLNNMFFPLCLINDNHSVTSLSHTKKTKSDNYSKHHKNTLIDNKALSLFKMDDHEKVIDLIQKMKRIYDSLPSGKI
TKETDRKIHKYFIDIASYANNKCDDRITRRVYLNKDKEVSIKVVYFINNVTVHNNTIEIPQTVNGGYDFSHLSLKGIVIK
DEDLSNSNFAGCRLQNAIFQDCNMYKTNFNFAIMEKILFDNCILDDSYFAQIKMTDGTLNSCSAMHVQFYNATMNRANIK
NTFLDYSNFYMAYMAEVNLYKVIAPYINLFRADLSFSKLDLINFKHADLSRVNLNKAILQNINLIDSKLFFTRLTNTFLE
MVICTDSNMANVNFNNANLNNCHFNCSVLTKAWMFNTRLYRVNFDEASVQGMGISILRGEENIPINSDTLVTLQKFFEED
CTSHTGMSQTENNTHEVAMKITADIMQHAD
>SEQF1516_EDU86970.1 sensory box sensor histidine kinase DcuS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRHSLPYRMLRKRPMKLSTTVILMVSAVLFSVLLVVHLIYFSQISDMTRDGLANKALAVARTLADSPEIRQGLQKKPQES
GIQAIAEAVRKRNDLLFIVVTDMQSLRYSHPEAQRIGQPFKGDDILKALNGEENVAINRGFLAQALRVFTPIYDENHKQI
GVVAIGLELSRVTQQINDSRWSIIWSVLFGMLVGLIGTCILVKVLKKILFGLEPYEISTLFEQRQAMLQSIKEGVVAVDD
RGEVTLINDAAQELLNYRKSQDDEKLSTLSHSWSQVVDVSEVLRDGTPRRDEEITIKDRLLLINTVPVRSNGVIIGAIST
FRDKTEVRKLMQRLDGLVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEDYILKTANNYQEEIGSLLGKIKSPVIAGF
LISKINRATDLGHTLILNSESQLPDSGSEDQVATLITTLGNLIENALEALGPEPGGEISVTLHYRHGWLHCEVNDDGPGI
APDKIDHIFDKGVSTKGSERGVGLALVKQQVENLGGSIAVESEPGIFTQFFVQIPWDGERSNR
>SEQF1516_EDU86971.1 glycerol-3-phosphate acyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFCYPCRAFALLTRGFTSFMSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYVLPYNSKADLLTLRAQC
LAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEV
NPPLRMLNGVQKFFAVLWLGRDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKL
LASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEL
VYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSV
EYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLR
NLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNIAADLMVRINNAGAANAMNLCCTALLASRQRSL
TREQLTEQLNCYLDLMRNVPYSTDSTVPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLP
SLMAAIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQDDELHINPVHSRTLQLLA
AGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAET
MKVYQLLAELITSDVRLTIESATQGEG
>SEQF1516_EDU86972.1 outer membrane lipoprotein Blc [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWYEIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYN
PDRGMWQQSEGKAYFTGAPTRAALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
REGFDVSKFIWVQQPGS
>SEQF1516_EDU86973.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWYQKTLTLSAKSRGFHLVTDEILNQLADMPRVNIGLLHLLLQHTSASLTLNENCDPTVRHDMERFFLRTVPDNGNYEHD
YEGADDMPSHIKSSMLGTSLVLPVHKGRIQTGTWQGIWLGEHRIHGGSRRIIATLQGE
>SEQF1516_EDU86974.1 acetate--CoA ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQIHKHTIPANIADRCLINPQQYEAMYQQSINAPDTFWGEQGKILDWIKPYQKVKNTSFAPGNVSIKWYEDGTLNLAAN
CLDRHLQENGDRTAIIWEGDDASQSKHISYKELHRDVCRFANTLLKLGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHS
VIFGGFSPEAVAGRIIDSNSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVVVLKRTGGKIDWQEGRDLWWHDQ
VEQASDQHQAEEMNAEDPLFILYTSGSTGKPKGVLHTTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGP
LACGATTLMFEGVPNWPTPARMAQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINPEAWEWYWK
KIGNEKCPVVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVDNEGNPLEGATEGSLVITDSWPGQARTLFGD
HERFEQTYFSTFKNMYFSGDGARRDEDSYYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHNIKGQAIY
AYVTLNHGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTSNLGDTSTLADPGVVEK
LLEEKQAIAMPS
>SEQF1516_EDU86975.1 sorbitol-6-phosphate 2-dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTWLNLQDKIIIVTGGASGIGLAIVEELLAQGANVQMVDIHGGDGQYEGHKGYQFWPTDISSAKEVNHTVAEIIQRFGR
IDGLVNNAGVNFPRLLVDEKAPAGQYELNEAAFEKMVNINQKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSC
YAATKAALNSFTRSWSKELGKHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQLREGYTKNAIPIGRAGRLAEIA
DFVCYLLSERASYITGVTTNIAGGKTRG
>SEQF1516_EDU86976.1 dipeptidase E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQTWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENA
EIVIVGGGNTFQLLKQCRERGLLAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTN
ALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGEEAVPLEAGHRF
>SEQF1516_EDU86977.1 ribose transport system permease protein RbsC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTSAKTSAKKMLMSDLMQTVGILPILILIVAVFGFITPNFFTESNLLNITRQASINIVLAAGMTFIILTGGIDLSVGSI
LGTTAVAAMVVSLSPEFAMLSIPAALMLGLLLGLFNGALVAFAGLPPFIVTLGTYTALRGAAYLLADGTTVINSNINFEW
IGNNYLGPVPWLVVIALAVIVVCWFILRRTTLGVHIYAVGGNMQAARLTGIKVWLVLLFVYGMSGLLSGLGGIMSASRLY
SANGNLGMGYELDAIAAVILGGTSFVGGIGTITGTLVGALIIATLNNGMTLMGVSYFWQLVIKGAMIIIAVLIDKYRTRH
HQSA
>SEQF1516_EDU86978.1 phosphatidylserine decarboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKYYKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDT
DPNVLVMPADGVISQLGKIEEDKILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTITPPREGIIKRWTWPAGENDGSVA
LLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSVTKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKD
QV
>SEQF1516_EDU86979.1 formate-dependent nitrite reductase complex, subunit NrfG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQPQIPVKMLTTLTILMVFLCIGSYLLSPKWQAVRAEYQRQRDPLHQFASQQNPEAQLQALQDKIRANPQNSEQWALLG
EYYLWQNDYSNSLLAYRQALQLRGENAELYAALATVLYYQASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANY
AQAIELWQKVMDLNSPRINRTQLVESINMAKLLQRRSD
>SEQF1516_EDU86980.1 D-xylose-proton symporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTQYNSSYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVAPQNLSESAANSLLGFCVASALIGCIIGGALGGYCSN
RFGRRDSLKIAAVLFFISGVGSAWPELGFTSINPDNTVPVYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIR
GKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLYTVPESPRWLMSRGKQEQAEGIL
RKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVGVIVIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTII
VGVINLTFTVLAIMTVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQAPGIVALLSMLFYVAAFAMSWGPVCWVLLSEIFP
NAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGCMGVLAALFMWKFVPETKGKTLEELEALWEP
ETKKTQQTATL
>SEQF1516_EDU86981.1 hypothetical protein ECH7EC4501_0251 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVAGLSNLSSDSENGWQWLPVFIFSAHCVSFCDILKK
>SEQF1516_EDU86982.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRTLKPLILNTGALALTLILIYTGISAHDKLTWLMEVTPVIIVVPLLLATAKRYPLTPLLYTLIFFHAIILMVGGQYTY
AKVPIGFEVQEWLGLSRNPYDKLGHFFQGLVPALVAREILVRGMYVRGRKMVAFLVCCVALAISAMYELIEWWAALAMGQ
GADDFLGTQGDQWDTQSDMFCALLGALTTVIFLARFHCRQLRRFGLITG
>SEQF1516_EDU86983.1 Sel1 repeat protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIIALMLFLTFFAHANDSEPGSQYLKAAEAGDRRAQYFLADSWFSSGDLSKAEYWAQKAADSGDADACALLAQIKITN
PVSLDYPQAKVLAEKAAQAGSKEGEVTLAHILVNTQAGKPDYPKAISLLENASEDLENDSAVDAQMLLGLIYANGVGIKA
DDDKATWYFKRSSAISRTGYSEYWAGMMFLNGEEGFIEKNKQKALHWLNLSCMEGFDTGCEEFEKLTNG
>SEQF1516_EDU86984.1 putative sulfatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKRLLKRPSLNLLAWLLLAAFYISICLNIAFFKQVLQALPLDSLHNVLVFLSMPVVAFSVINIVLTLSSFLWLNRPLAC
LFILVGAAAQYFIMTYGIVIDRSMIANIIDTTPAESYALMTPQMLLTLGFSGVLAALIACWIKIKPATSRLRSVLFRGAN
ILVSVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVRIGEDAHRNPLMQNEKRKNLTIL
IVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTASCGTATAVSVPCMFSDMPREHYKEELAQHQEGVLDIIQRAGINV
LWNDNDGGCKGACDRVPHQNVTALNLPDQCINGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHRPTYYNRYPPQFRKF
TPTCDTNEIQTCTKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSLVYLSDHGESLGENGIYLHGLPYAIAPDSQK
QVPMLLWLSEDYQKRYQVDQNCLQKQAQTQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSE
>SEQF1516_EDU86985.1 cytochrome c nitrite reductase, Fe-S protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTWSRRQFLTGVGVLAAVSGTAGRVVAKTLNINGVRYGMVHDESLCIGCTACMDACREVNKVPEGVSRLTIIRSEPQGEF
PDVKYRFFRKSCQHCDHAPCVDVCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVTKTADKCDFCRKTNL
QAGKLPACVEACPTKALTFGNLDDPNSEISQLLRQKPTYRYKLALGTKPKLYRVPFKYGEVSQ
>SEQF1516_EDU86986.1 tRNA-dihydrouridine synthase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKINQTSAMPEKTDVHWSGRFSVAPMLDWTDRHCRYFLRLLSRNTLLYTEMVTTGAIIHGKGDYLAYSEEEHPVALQLG
GSDPAALAQCAKLAEARGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDDQDSYEF
LCDFINTVSGKGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDFPHLTMSINGGIKSLEEAKAHLQHMDGVM
VGREAYQNPGILAAVDREIFGSSDTDADPVAVVRAMYPYIERELSQGTYLGHITRHMLGLFQGIPGARQWRRYLSENAHK
AGADINVLEHALKLVADKR
>SEQF1516_EDU86987.1 sensor histidine kinase BasS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLMRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQIQLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMV
SLTLFICYQAVRRITRPLAELQKELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDVILPSYDELSTMLDQRQQTLL
LPESAADITVQGDATLLRMLLRNLVENAHRYSPQGSNIMIKLQEDGGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGG
IGLGLSIVSRITQLHHGQFFLQNRQETSGTRAWVRLKKDQNVANQI
>SEQF1516_EDU86988.1 hypothetical protein ECH7EC4501_0198 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFFYPSRAHWAASAISRTSGREVAAVTSQRHAELSSAINHGKLPLHE
>SEQF1516_EDU86989.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLGHISKFDGNNSLIKHGVVQGNNIVDFDLLRNFNGGPGLNRENFIYISNIFLNIKQRNEKNHSINMFREVSISGDIVSV
KFYRNEKIECACDFMMAKDAQGYIDLSELDLTSCHFKGDVISKVSFISSNLQHVTFECKEIGDCNFTTAIVDNVIFKCRR
LHNVIFIKASGDYVDFSKNILDTVDFSQSQLTHSNFCECQIRNSNFDHCYLYASHFTRAEFLTDKEISFIKSNLTAVMFD
HVRISTGNFKDSVTQLMVLSIDYSDIFGNEYLDGYINNIIKMIDSLPDDPAILKSVLAVKLVMQLKILNIVNKNFIENMK
KIFSHGPYIKDPIIRSYIHPDEDNKFDNFMRQNRFSKVNFDTQQMIDFINRFNMNKWLIDRNNNFFIQLIDQALRSTNDT
IKENAWHLYKEWIRSDDVSPLFIEIEDNLRTFNTNELTRNDNIFILFSSVDDGPVMVVSSQRLHDMLNPTKDTNWNSTYI
YKSRHEMLPVNLTPETLFGSKSYDKHALFPIFTASWRANRIKNKGI
>SEQF1516_EDU86990.1 inorganic phosphate transporter, sodium-dependent [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTLLNLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKKPLAFCAGIGVTALVQSSNATTMLVTSFVAQDLVALA
PALVIVLGADVGTALMARILTFDLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGV
QVIFASLTGDILLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANLGSGLLAMLNNSAANAAARRVAL
GSLLFKLVGSLIILPFVHLLAETMGKLSLPKAELVIYFHVFYNLVRCLAMLPFVDPMARFCKTIIRDEPELDTQLRPKHL
DVSALDTPTLALANAARETLRIGDAMEQMMEGLNKVMHGEPRQEKELRKLADDINVLYTAIKLYLARMPKEELAEEESRR
WAEIIEMSLNLEQASDIVERMSSEIADKSLAARRAFSLDGLKELDALYEQLLSNLKLAMSVFFSGDVTSARRLRRSKHRF
RILNRRYSHAHVDRLHQQNVQSIETSSLHLGLLGDMQRLNSLFCSVAYSVLEQPDEDEGRDEY
>SEQF1516_EDU86991.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTVLSRMAMQLKKTAWIIPVFMVSGCSLSPAIPVIGAYYPSWFFCAIASLILTLITRRVIQRANIKLAFVGIIYTALFA
LYAMLFWLAFF
>SEQF1516_EDU86992.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALPRITQKEMTEREQRELKTLLDRARIAHGRVLTNSETNSIKKEYIDKLMVEREAEAKKARQLKKKQAYKPDPEASFSW
SANTSTRGRR
>SEQF1516_EDU86993.1 translation elongation factor P [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLRRLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGE
FWHFMNNETFEQLSADAKAIGDNAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
VVKVPLFVQIGEVIKVDTRSGEYVSRVK
>SEQF1516_EDU86994.1 anaerobic C4-dicarboxylate transporter DcuB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLFTIQLIIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQPGKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEK
LLRRNPKYVSIVAPFVTCTLTILCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
NVTFDGRHLEFLDLLAITIPSTLIGILAIGIFSWFRGKDLDKDEEFQKFISVPENREYVYGDTATLLDKKLPKSNWLAMW
IFLGAIAVVALLGADSDLRPSFGGKPLSMVLVIQMFMLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAET
MFGAHMSEIQGVLGEMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYILPTYPSDLA
AIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL
>SEQF1516_EDU86995.1 regulatory protein SoxS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDL
GYVSQQTFSRVFRRQFDRTPSDYRHRL
>SEQF1516_EDU86996.1 bacterial phosphonate metabolism protein PhnH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLETAFMLPVQDAQHSFRRLLKAMSEPGVIVALHQLKRGWQPLNIATTSVLLTLADNDTPVWLAAPLSNDIVSQSLRFH
TNAPLVSQPEQATFAVTDEAISSEQLNALSTGTAVAPEAGATLILQVASLSGGRMLRLTGAGIAEERMIAPQLPECILHE
LTERPHPFPLGIDLILTCGERLLAVPRTTHVEVC
>SEQF1516_EDU86997.1 phosphonate C-P lyase system protein PhnK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGKTTLLKSISARLTPQQGEIHYENRSLYGMSEADRRRL
LRTEWGVVHQHPLDGLRRQVSAGGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLVMKQGQVVESGLTDRVLDDPHHP
YTQLLVSSVLQN
>SEQF1516_EDU86998.1 lysyl-tRNA synthetase homolog GenX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMSQATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYH
MKRLLVAGCGPVFQLCRSFRNEEMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPASQASLAQISTEDHRVAERFEVYY
KGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQHPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAF
SVDRA
>SEQF1516_EDU86999.1 cytochrome c-type biogenesis protein NrfE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSLGVNVLTPLTAFAGVRLRWPAMMRLTCIGILAQFALLLLAFGVLTYCFLISDFSVIYVAQHSYSLLSWKLKLAAVWG
GHEGSLLLWVLLLSAWSALFAWQYRQQTDPLFPLTLAVLSLMLAALLLFVVLWSDPFVRIFPPAIEGRDLNPMLQHPGLI
FHPPLLYLGYGGLMVAASVALASLLRGEFDGACARICWRWALPGWSALTAGIILGSWWAYCELGWGGWWFWDPVENASLL
PWLSATALLHSLSLTRQRGIFRHWSLLLAIVTLMLSLLGTLIVRSGILVSVHAFALDNVRAVPLFSLFALISLASLALYG
WRARDGGPAVRFSGLSREMLILATLLLFCAVLLIVLVGTLYPMIYGLLGWGRLSVGAPYFNRATLPFGLLMLVVIVLATF
VSGKRAQLPALLAHAGILLFAAGIVVSSVSRQEISLNLQPGQQVTLAGYTFRFERLDLQAKGNYTSEKAIVALFDHQQRI
GELTPERRFYEARRQQMMEPSIRWNGIHDWYAVMGEKTGADRYAFRLYVQSGVRWIWGGGLLMIAGALLSGWRGKKRDV
>SEQF1516_EDU87000.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRSAINDILGHTRQFFSQHDVHLPPFASFSPAQWQQLDTAAWEEVFDLKLGWDVTAFGRNNFAAHGLTLFTLRNGSAKG
MPYVKCYAEKIMHVRDAQVTPMHFHWRKREDIINRGGGNLIVELWNADSNEQTADSDITVVIDGCRQKHTAGSQLRLSPG
ESICLPPGLYHSFWAEAGFGDVLVGEVSSVNDDDHDNHFLQPLDRYNLIDEDEPAQLVLCNEYRQFR
>SEQF1516_EDU87001.1 inorganic anion transporter, sulfate permease (SulP) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVIVVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWAN
LPLAIGCAISLTAFTAFSLVLGQHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANG
VGLVIKNPLDGLPVALGDFATFPVIMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGLIFDPNVHFSGVFAMPSLSDENG
NSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVY
IESAAGTAAGGKTGLTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGLVTAVFIVL
TCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI
>SEQF1516_EDU87002.1 hypothetical protein ECH7EC4501_0264 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRWFVDFFNAYDQYHLRGMLRNPLTTELFAALMHNNASLWQD
>SEQF1516_EDU87003.1 chorismate lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHPALTQLRALRYCKEIPALEPQLLDWLLLEDSMTKRFEQQGKTVSVTMIREGFVEQNEIPEELPLLPKESRYWLREIL
LCADGEPWLAGRTVVPVSTLSGPELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLP
ASPLY
>SEQF1516_EDU87004.1 class B acid phosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKITQAISAVCLLFALNSSAVALASSPSPLNPGTNVARLAEQAPIHWVSVAQIENSLAGRPPMAVGFDIDDTVLFSSPG
FWRGKKNFSPESEDYLKNPVFWEKMNNGWDEFSIPKEVARQLIDMHVRRGDAIFFVTGRSPTKTETVSKTLADNFHIPAT
SMNPVIFAGDKPGQNTKSQWLQDKNIRIFYGDSDNDITAARDVGARGIRILRASNSTYKPLPQAGAFGEEVIVNSEY
>SEQF1516_EDU87005.1 phosphonate metabolism protein PhnI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYVAVKGGEKAIDAAHALQESRRRGDTDLPELSVAQIEQQLNLAVDRVMTEGGIADRELAALALKQASGDNVEAIFLLRA
YRTTLAKLAVSEPLDTTEMRLERRISAVYKDIPGGQLLGPTYDYTHRLLDFTLLANGEAPTLTTADSEQQPSPHVFSLLA
RQGLAKFEEDSGAQPDDITRTPPVYPCSRSSRLQQLMRGDEGYLLALAYSTQRGYGRNHPFAGEIRSGYIDVSIVPEELG
FAVNVGELLMTECEMVNGFIDPPDESPHFTRGYGLVFGMSERKAMAMALVDRALQAPEYGEHATGPAQDEEFVLAHADNV
EAAGFVSHLKLPHYVDFQAELELLKRLQQEQNHG
>SEQF1516_EDU87006.1 maltose-inducible porin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGEQQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGD
KSFYFDTNVAYSVAQQNDWEATDPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVG
FGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEVNPGGTLELGVDYGRANLRDNYRLVDGASKDGWLF
TAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSGVAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDI
NWDNDNGTKWWTVGIRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFATYAKWDEK
WGYDYNGDSKVNPNYGKAVPADFNGGSFGRGDSDEWTFGAQMEIWW
>SEQF1516_EDU87007.1 melibiose operon regulatory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTDTFMCSSDEKQTRSPLSLYSEYQRMEIEFRAPHIMPTSHWHGQVEVNVPFDGDVEYLINNEKVNINQGHITLFWACI
PHQLTDTGTCQSMAIFNLPMHLFLSWPLDKDLINHVTHGMVIKSLATQQLSPFEVRRWQQELNSPNEQIRQLAIDEIGLM
LKRFSLSGWEPILVNKTSRTHKNSVSRHAQFYVSQMLGFIAENYDQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYI
TAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYSTFGKYVGMSPQQYRKLSQQRRQTFPG
>SEQF1516_EDU87008.1 zinc uptake regulation protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKTTTQELLAQADKICAQRNVRLTPQRLEVLRLMSLQDGAISAYDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVE
STNSYVLCHLFDQPTHTSAMFICDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
DHSVQVKKKPR
>SEQF1516_EDU87009.1 phosphonate utilization protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLTLTLTGSGGAQGVPAWGCECAACARARRSPHYRRQPCSGVVKFNEAITLIDAGRHDLADRWSPGSFQQFLLTHYHMD
HVQGLFPLRWGVGDPIPVYGPPDEQGCDDLFKHPGLLDFSHTVEPFVVFDLQGLQVTPLPLNHSKLTFGYLLETAHSRVA
WLSDTAGLPEKTLKFLRNNQPQVMVIDCSHPPREDAPRNHCDLNTVLALNQVIRSPRVVLTHISHQFDAWLMENALPSGF
EAGFDGMEIGVA
>SEQF1516_EDU87010.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAISIKGVNTGVIRKSNNFIALALKIKEPRNKESLFFMSVMELRDLLIALESRLHQKHKLDAAARLQYEQARDKVIKKMA
ENIPEILVDELKNADINRRVNTLELTDNQGENLTFVLTLHDGSKCELVVNELQIEMLARAIIHAINNAEMRELALRITSL
LDFLPLYDVDCQQNGNLEYDTYSQPEWKHNLFDHYLAVLYRFKDESGKEQFSGAVVKTREATPGKEIEAITRRMLDFSPR
LKKLVGVPCQVYVRTVAANNAQPLTQDQCLRALHHLRVQSTSKTAPQAK
>SEQF1516_EDU87011.1 isocitrate lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECTLAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQ
AKAGIEAVYLSGWQVAADANLAASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEA
GFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARLAADVTGVPTLLVARTDADAADL
ITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRGLAYAPYADLVWCETSTPDLELARRFAEAIHAKYPGKLLAYNCSP
SFNWQKNLDDNTIASFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKDGYTFVSHQ
QEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF
>SEQF1516_EDU87012.1 multidrug resistance protein MdtO [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSALNSLPLPVVRLLAFFHEELSERRPGRVPQTVQLWVGCLLVILISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILF
VVATVLEIGSLFLIYKWSYGEPLIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCI
VVGLYPTLLMTLIGVLWFPSRAISQMHQALNDRLDDAISHLTDSLAPLPETRIEREALALQKLNVFCLADDANWRTQSAW
WQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKLASEINKLQHAITEGQCWQSDWRISESEAMAARECNLENICQTLL
QLGQMDPNTPPTPAAKPPSMVADAFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVANPNVGSSYQKMVL
RFGGAFCGAILALLFTLLVMPWLDNIVELLFVLAPIFLLGAWIATSSERSSYIGTQMVVTFALATLENVFGPVYDLVEIR
DRALGIIIGTVVSAVIYTFVWPESEARTLPQKLAGALGMLSKVMRIPRQQEVTALRTYLQIRIGLHAAFNACEEMCQRVA
LERQLDSEERALLIERSQTVIHQGRDLLHAWDATWNSAQALDNALQPDKAGQFADALEKYAAGLATALSRSPQITLEETP
ASQAILPTLLKQEQHVCQLFARLPDWTAPALTPATEQAQGATQ
>SEQF1516_EDU87013.1 transcriptional regulator, TetR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQREDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPDKEAILYDALRYLSQQIDVWRRQLMLDETQTAEQKLL
ARYQALSECVKNNRYPGCLFIAACTFYPDPGHPIHQLADQQKSAAYDFTHELLTTLEVDDPAMVAKQMELVLEGCLSRML
VNRSQADVDTAHRLAEDILRFARCRQGGALT
>SEQF1516_EDU87014.1 hypothetical protein ECH7EC4501_0274 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGEYRNPKLMSLAFGGAEAPKSIYFKNIYSQLINKIYKL
>SEQF1516_EDU87015.1 phosphonate ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDAVQAPYPAYRPEPNMQTITIAPPKRSWFSLLSWAVVLAVLVVSWQGAEMAPLTLIKDGGNMATFAADFFPPDFSQWQ
DYLTEMLVTLQIAVWGTALAVVLSIPFGLMSAENLVPWWVYQPVRRLMDACRAINEMVFAMLFVVAVGLGPFAGVLALFI
HTTGVLSKLLSEAVEAIEPGPVEGIRATGANKLEEILYGVLPQVMPLLISYSLYRFESNVRSATVVGMVGAGGIGVTLWE
AIRGFQFQQTCALMVLIIVTVSLLDFLSQRLRKHFI
>SEQF1516_EDU87016.1 chaperonin GroL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSFGAPTITKDGVSVAREIELEDKFENMGAQMVKEVASK
ANDAAGDGTTTATVLAQAIITEGLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGK
LIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESPFILLADKKISNIREMLPVLEAV
AKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAVKAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQA
KRVVINKDTTTIIDGVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDAL
HATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAPLRQIVLNCGEEPSVVANTVKGGDGNYGYNA
ATEEYGNMIDMGILDPTKVTRSALQYAASVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM
>SEQF1516_EDU87017.1 amino acid/peptide transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDNHAISLFSAYASLVYVTPILGGWLADRLLGNRTAVIA
GALLMTLGHVVLGIDTNSTFSLYLALAIIICGYGLFKSNISCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLA
AQWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVMLCLAPVFFTLLLENDWSGYLLA
IVCLIAAQIIARMMIKFPEHRRALWQIVLLMFVGTLFWVLAQQGGSTISLFIDRFVNRQAFNIEVPTALFQSVNAIAVML
AGVVLAWLASPESHGNSTLRVWLKFAFGLLLMACGFMLLAFDARHAAADGQASMGVMVSGLALMGFAELFIDPVAIAQIT
RLKMSGVLTGIYMLATGAVANWLAGVVAQQTTESQISGMAIAAYQRFFSQMGEWTLACVAIIVVLAFATRFLFSTPTNMV
QESND
>SEQF1516_EDU87018.1 alanine racemase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAGGITKPVLLLEG
FFDARDLPTISAQHFHTAVHNEEQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHF
ARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVSPLEDRSTGADFGCQPVMSLTSS
LIAVREHKVGEPVGYGGTWISERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGD
PVILWGEGLPVERIAEMTKVSAYELITRLTSRVAMKYVD
>SEQF1516_EDU87019.1 phosphonate C-P lyase system protein PhnG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHADTATRQHWMSVLAHSQPAELAARLNALNITANYEVIRAAETGLVQIQARMGGTGERFFAGDATLTRAAVRLTDGTLG
YSWVLGRDKQHAERCALIDALMQQTRHFQNLSETLIAPLDADRMARIAARQAEVNASRVDFFTMVRGDNA
>SEQF1516_EDU87020.1 phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMGKLIWLMGPSGSGKDSLLAELRLREQTQLLVAHRYITRDASAGSENHIALSEQEFFTRAGQNLLALSWHANGLYYGVG
VEIDLWLHAGFDVLVNGSRAHLPQARARYQSALLPICLQVSPEILRQRLENRGRENASEINARLARAARYTPQDCHTLNN
DGSLRQSVDTLLTLIHQKEKHHACL
>SEQF1516_EDU87021.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVISIRRSRHEEGEELVAIWCRSVDATHDFLSAEYRAELEELVRSFLPEAPLWVAVNERDQPVGFMLLSGQHMDALFIDP
DVRGCGVGRMLVKHALSMAPELTTNVNEQNEQAVGFYKKVGFKVTGRSEVDDLGKPYPLLDLAYVGE
>SEQF1516_EDU87022.1 PTS system, mannose/fructose/sorbose family, IID component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQRKITRGDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIKRLYPVKEDQVAALRRHLVFFNTTPAVCGPVIGVTAA
MEEARANGAEIDDGTINGIKVGLMGPLAGVGDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNAVRLAMKWYGLQL
GFRKGVNIVSDMGGNVLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTHAADGSTVTMTVQNILDQLCPGLLALGLT
LLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS
>SEQF1516_EDU87023.1 RND efflux system, outer membrane lipoprotein, NodT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKLADDIHLASSGWPQAQWWKQLNDPQLDALIQRTLSGS
HTLAEAKLREEKAQSQADLLDAGSQLQVAALGMLNRQRVSANGFLSPYAMDAPALGMDGPYYTEATVGLFAGLDLDLWGV
HRSAVTAAIGAHNAALAETAAVELSLTTGVAQLYYSMQASYQMLDLLEQTRDVIDYAVKAHQSKVAHGLEAQVPFHGARA
QILAVDKQIAAVKGQITETRESLRALIGAGASDMPEIKPVALPRVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDS
ARALFYPSFDIKAFFGLDSIHLDTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVLNAVRDVAV
NGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPVLAEEMSLLMLDSRRVIQSIQLMKSLGSGYQ
AAPVVEKK
>SEQF1516_EDU87024.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALFSKILIFYVIGVNISFVIIWFISHEKTHIRLLSAFLVGITWPMSLPVALLFSLF
>SEQF1516_EDU87025.1 Na+/H+ antiporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEIFFTILIMTLVVSLSGVVTRVMPFQIPLPLMQIAIGALLAWPTFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLE
HGREIFGLALALVVVTVVGIGFLIYWVVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGL
VSLKFAVAVAMGTMIFTVGGATVEFMKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEPATQIVLLFLLPFASYLIAEHIG
VSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWAMLEFVFNGMVFLLLGLQLPGILETSLMAAEIDPNVEIWMLFTDI
ILIYAALMLVRFGWLWTMKKFSNRFLKKKPMEFGSWTTREILIASFAGVRGAITLAGVLSIPLLLPDGNVFPARYELVFL
AAGVILFSLFVGVVMLPILLQHIEVADHSQQLKEERIARAATAEVAIVAIQKMEERLAADTEENIDNQLLTEVSSRVIGN
LRRRADGRNDVESSVQEENLERRFRLAALRSERAELYHLRATREISNETLQKLLHDLDLLEALLIEENQ
>SEQF1516_EDU87026.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLTTGVVLLRWQLLSAVMMFLASTLNIRFRRSDYVGLAVISSGLGVVSACWFAMGLLGITMADITAIWHNIESVMIEE
MNQTPPQWPMILT
>SEQF1516_EDU87027.1 DNA-damage-inducible protein F [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVYLGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAK
NPQALARALVQPLLLALGAGALIALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
PVILLVVGNILNIVLDVWLVMGLHMNVRGAALATVIAEYATLLIGLLMVRKILKLRGISGEMLKTSWRGNFRRLLALNRD
IMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTLLTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGI
VALLFSVVYLLAGEHIIALLASLTQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAAGFALTLLT
LPWLGNHGLWLALTVFLALRGLSLAAIWRRHWRNGTWFAAT
>SEQF1516_EDU87028.1 putative cadaverine:lysine antiporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSAKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWIISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPA
FGFQTGVLYYHANWIGNLAIGITAVSYLSTFFPVLNDPVPAGIACIAIVWVFTFVNMLGGTWVSRLTTIGLVLVLIPVVM
TAIVGWHWFDAATYAANWNTADTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKRTVPLATMLGTGLAGIVYIAATQ
VLSGMYPSSVMAASGAPFAISASTILGNWAAPLVSAFTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDSNGIPK
KGLLLAAVKMTALMILITLMNSAGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGVNIRNFVSLICSVLGCVFCFIA
LMGASSFELAGTFIVSLIILMFYARKMHERQSHSMDNHTASNAH
>SEQF1516_EDU87029.1 anaerobic C4-dicarboxylate transporter DcuA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGNIPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLL
RRNPKYITILAPIVTYFLTIFAGTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH
GISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIEIKSGAKTSVWLFLLGVVGVVIY
AIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVICKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKD
TAGEVIQGHPWLLAVIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQMDDTGTTR
IGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML
>SEQF1516_EDU87030.1 proline/betaine transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKRKKVKPITLRDVTIIDDGKLRKAITAASLGNAMEWFDFGVYGFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRP
LGGLFFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGEYTGASIFVAEYSPDRK
RGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIPFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDRE
GLQDGPKVSFKEIATKYWRSLLTCIGLVIATNVTYYMLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSD
RFGRRPFVLLGSVALFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAAFNISVLVA
GLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETANRPLKGATPAASDIQEAKEILVEHYDNIEQKIDDIDHE
IADLQAKRTRLVQQHPRIDE
>SEQF1516_EDU87031.1 maltose/maltodextrin-binding periplasmic protein MalE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATG
DGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPA
LDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE
AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVN
KDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK
>SEQF1516_EDU87032.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYTQTLYELSQEAERLLQLSRQQLQLLEKMPLSVPGDDAPQLALPWSQPNIAERHAMLNNELRKISRLEMVLAIVGTMKA
GKSTTINAIVGTEVLPNRNRPMTALPTLIRHTPGQKEPVLHFSHVAPIDCLIQKLQQRLRDCDIKHLTDVLEIDKDMRAL
MQRIENGVAFEKYYLGAQPIFHCLKSLNDLVRLAKALDVDFPFSAYAAIEHIPVIEVEFVHLAGLESYPGQLTLLDTPGP
NEAGQPHLQKMLNQQLARASAVLAVLDYTQLKSISDEEVREAILAVGQSVPLYVLVNKFDQQDRNSDDADQVRALISGTL
MKGCITPQQIFPVSSMWGYLANRARHELANNGKLPPPEQQRWVEDFAHAALGRRWRHADLADLEHIRHAADQLWEDSLFA
QPIQMLLHAAYANASLYALRSAAHKLLNYAQQAREYLDFRAHGLNVACEQLRQNIHQIEESLQLLQLNQAQVSGEIKHEI
ELALTSANHFLRQQQDALKVQLAALFQDDSEPLSEIRTRCETLLQTAQNTISRDFTLRFAELESTLCRVLTDVIRPIEQQ
VKMELSESGFRPGFHFPVFHGVVPHFNTRQLFSEVISRQEATDEQSTRLGVVRETFSRWLNQPDWGRGNEKSPTETVDYS
VLQRALSAEVDLYCQQMAKVLAEQVDESVTAGMNTFFAEFASCLTELQTRLRESLALRQQNESVVRLMQQQLQQTVMTHG
WIYTDAQLLRDDIQTLFTAERY
>SEQF1516_EDU87033.1 two component transcriptional regulator, winged helix family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPVVLVVDDDTAICALLQDVLSEHVFTVSVCHTGQEAILRIEGDPDIALVVLDMMLPDTNGLRVLQQIQKLRPTLPVVM
LTGMGSESDVVVGLEMGADDYICKPFTPRVVVARLKAVLRRVGALAVNDEKSAGLSFNGWYLDTMRCQLHNPLQQHVELT
QGEYGLLLALAQNARRVLSREQLLAFTHSDSVEVFDRTIDVLIMRLRRKIELNPHQPMLIKTLRGLGYVFAADVH
>SEQF1516_EDU87034.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRPAFILICLLLQACSATTKELGNSLWDSLFGTPGVQLTDDDIQNMPYASQYMQLNGGPQLFVVLAFAEDGQQKWVTQD
QATLVTQHGRLVKTLLGGDNLIEVNNLAADPLIKPAQIIDGATWMRTMGWTEYQQVRYATARSVFKWDGTGTVKVGSDET
AVRVLDEEVSTDQARWHNRYWIDSGGQIRQSEQYLGADYFPVKTTLIKAAKQ
>SEQF1516_EDU87035.1 fumarate reductase, flavoprotein subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRSHTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQ
DVVDYFVHHCPTEMTQLELWGCPWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
ILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMALSHGVPLRDMEFVQYHPTGLPGS
GILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLGEPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHL
GEKKLHERLPFICELAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRLGSNSLAEL
VVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWAKIRDEMGLAMEEGCGIYRTPELMQKTIDKL
AELQERFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTKRDDVNFLKHTLAFRDADG
TTRLEYSDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG
>SEQF1516_EDU87036.1 amino acid-polyamine-organocation (APC) permease family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGLKQELGLAQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWAWPILIILVFPIAIVFAILGRHYPSAGGVAHFVGMAF
GSRLERVTGWLFLSVIPVGLPAALQIAAGFGQAMFGWHSWQLLLAELGTLALVWYIGTRGASSSANLQTVIAGLIVALIV
AIWWAGDIKPASIPFPAPGNIELTGLFAALSVMFWCFVGLEAFAHLASEFKNPERDFPRALMIGLLLAGLVYWGCTVVVL
HFDAYGEQMAAAASLPKIVVQLFGVGALWIACVIGYLACFASLNIYIQSFARLVWSQAQHNPDHYLARLSSRHIPNNALN
AVLGCCVVSTLVIHALEINLDALIIYANGIFIMIYLLCMLAGCKLLQGRYRLLAVVGGLLCVLLLAMVGWKSLYALIMLA
GLWLFLPKRKTPENGITT
>SEQF1516_EDU87037.1 fumarate hydratase class I, anaerobic [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNKPFIYQAPFPMGKDNTEYYLLTSDYVSVADFDGETILKVEPEALTLLAQQAFHDASFMLRPAHQKQVAAILHDPEAS
ENDKYVALQFLRNSEIAAKGVLPTCQDTGTAIIVGKKGQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNT
GTNLPAQIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRTLGTAACPPYHIAFVIGGTSVET
NLKTVKLASAHYYDELPTEGNEHGQAFRDVQLEQELLEKAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSA
DRNIKAKINREGIWIEKLEHHPGQYIPQELRQAGEGEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVGRDIAHAKL
KELIDAGKELPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDLLQSHGGSMIMLAKGNRSQQVTDACHKHGGF
YLGSIGGPAAVLAQQSIKHLECVAYPELGMEAIWKIEVEDFPAFILVDDKGNDFFQQIINKQCANCTK
>SEQF1516_EDU87038.1 PTS system, mannose/fructose/sorbose family, IIA component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNAIFCAHGKLACAMLESVQMVYGNANVEAVEFVPGENAGDIVAKLEKLVSIHNQNEWLIAVDLQCGSPWNAAAMLAMR
NPRLRVISGLSLPLALELVDNQDSMNVDELCEHLTQIAKQTCVVWKQLATTEEDF
>SEQF1516_EDU87039.1 ribose import ATP-binding protein RbsA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSTPVLEMRNIAKAFGKFYALKGVDLTVYPGEIHALMGENGAGKSTLMKVLAGAYTATSGEILIDGKPFHIRTPKDALS
AGITLIYQEMQLAPNLSVAENIFLGSELSHGGLVQRKEMLVQAQKVIDRLGAQFNASDKVMTLTIAEQQQVEIARALHRN
SRILVMDEPTAALSSRETHRLFELIMRLRDEGMAIIYISHRMAEVYELSDRVSVLRDGQYVGSLTRDNLNAGELVRMMVG
RPLSDLFNKERDIPLGKARLNVHHLTDGGKVQPSSLLVRSGEIVGLAGLVGAGRSELAQLIFGVRKATGGMIEVDGEPVV
IHSPREAIDLGIGFLTENRKEQGLFLEMAAAENITMATLERDARWGMLNRKKAQTISDDAIKLLNIRVPHAQVRAGGLSG
GNQQKLLISRWVAIGPRILLLDEPARGVDVGAKSEIYRIMNEMARKGVAILMISSELPEIVGMSDRVYVMREGSIAGELN
GKNITQENIMTLATGVNDAHSQAVTS
>SEQF1516_EDU87040.1 methionine synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIE
TNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTARTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLV
AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA
LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAQAGFLNIVGGCCGTTPQHIAA
MSRAVEGLAPRKLPEIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDI
NMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLLRRYGAAV
VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISG
GVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRG
SKTDDTANAQQAEWRSWEVNKRLEYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK
SARVMKQAVAYLEPFIEASKEQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNADL
IGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFV
ARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDFAFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY
PRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLRQQTEKTGFAN
YCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENL
SNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQV
EDYARRKGMSVSDVERWLAPNLGYDAD
>SEQF1516_EDU87041.1 maltose/maltodextrin ABC transporter, permease protein MalG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNFATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFP
VLLWLWNSVKVAGISAIGIVALSTTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHG
GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVVFILSFIAAITEVPVASLLLRDV
NSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITIVFLLAQRWLVNGLTAGGVKG
>SEQF1516_EDU87042.1 arginine/agmatine antiporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIYGWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRC
FGPFLGYQTNVLYWLACWIGNIAMVVIGVGYLSYFFPILKDPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALI
PIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVKNPKRNVPIATIGGVLIAAVCYV
LSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGAIVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKA
GTPVAGLIIVGILMTIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTTIAFLYCIW
AVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD
>SEQF1516_EDU87043.1 ribosome small subunit-dependent GTPase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIVISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVV
WRPGKPAAEGVNVKGIVEAVHERTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLN
KIDLLDDEGMAFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGVGKSSLLNALLGLQKEILTNDVS
DNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLWHLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGK
IAETRFENYHRILESMAQVKTRKNFSDTDD
>SEQF1516_EDU87044.1 phosphonate metabolism protein PhnJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANLSGYNFAYLDEQTKRMIRRAILKAVAIPGYQVPFGGREMPMPYGWGTGGIQLTASVIGESDVLKVIDQGADDTTNAV
SIRNFFKRVTGVNTTERTDDATVIQTRHRIPETPLTEDQIIIFQVPIPEPLRFIEPRETETRTMHALEEYGVMQVKLYED
IARFGHIATTYAYPVKVNGRYVMDPSPIPKFDNPKMDMMPALQLFGAGREKRIYAVPPFTRVESLDFDDHPFTVQQWDEP
CAICGSTHSYLDEVVLDDAGNRMFVCSDTDYCRQQSEAKSQ
>SEQF1516_EDU87045.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEIREGHNKFYINDEQGKQIAEIVFVPTGENLAIIEHTDVDESLKGQGIGKQLVAKVVEKMRREKRKIIPLCPFAKHEFD
KTREYDDIRS
>SEQF1516_EDU87046.1 cation/acetate symporter ActP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRNDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE
AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATERE
ELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMMGGWLGLITAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSITVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH
>SEQF1516_EDU87047.1 excinuclease ABC, A subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS
PAISIEQKSTSHNPRSTVGTITEIHDYLRLLYARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLAESFETALELSGGTAVVADMDDP
KAEELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQM
LKSLADHYKFDVEAPWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSAVREELAKF
ISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAGQRAKIAEKILKEIGDRLKFLVNVGLNYLTL
SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDI
GPGAGVHGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLKDVTLTLPVGLFTCITG
VSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHFDKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPE
SRARGYTPGRFSFNVRGGRCEACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEAREFF
DAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLDVLHKLRD
QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVSGTPETVAECEASHTARFLKPML
>SEQF1516_EDU87048.1 alpha-galactosidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMSAPKITFIGAGSTIFVKNILGDVFHREALKTAHIALMDIDPTRLEESHIVVRKLMDSAGASGKITCHTQQKEALQDAD
FVVVAFQIGGYAPCTVTDFEVCKRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPDATMLNYVNPMAMNTWAM
YARYPHIKQVGLCHSVQGTAEELARDLNIDPATLRYRCAGINHMAFYLELERKTADGSYVNLYPELLAAYDAGQAPKPNI
HGNTRCQNIVRYEMFKKLGYFVTESSEHFAEYTPWFIKPGREDLIERYKVPLDEYPKRCVEQLANWHKELEEYKNASRID
IKPSREYASTIMNAIWTGEPSVIYGNVRNDGLIDNLPQGCCVEVACLVDANGIQPTKVGTLPSHLAALMQTNINVQTLLT
EAILTENRDRVYHAAMMDPHTAAVLGIDEIYALVDDLIAAHGDWLPGWLHR
>SEQF1516_EDU87049.1 L-sorbose 1-phosphate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTTALRLYGKRDLRLETFDLPEMQEDEILATVVTDSLCLSSWKEANLGENHKKVPDDVATNPIIIGHEFCGDILAVGKK
WQHKFQPGQRYVIQANLQLPDRPDCPGYSFPWVGGEATHVVIPNEVMEQDCLLAYDGETYFEGSLVEPLSCVIGAFNANY
HLQEGSYNHTMGIRPQGRMLILGGTGPMGLLAIDYALHGPVNPSLLVITDTDNDKLSYARKHYPSEPQTLIHYLNAADAA
FDTLMALSGGHGFDDIFVFVPNEGLVTLASSLLATDGCLNFFAGPQDKHFSAPINFYDVHYAFTHYVGTSGGNTDDMRAA
VKLIEEKKVQAAKVVTHILGLNAAGETTLELPAVGGGKKLVYTGKYLPLTSLTQIQDQALAAILARHQGIWSGEAEQYLL
THAEAISHD
>SEQF1516_EDU87050.1 multidrug resistance protein MdtN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYVSADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRID
PRPYEANLAKSEASLAALDKQIMLTQRSVDAQQFGADSVNATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTA
QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGRVISLKTSVGQFASAMRPIFTLI
DTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKTFEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKI
MVDKPDPEMFRIGASAVANLEPQ
>SEQF1516_EDU87051.1 diacylglycerol kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANNTTGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVVIACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVV
DRIGSEYHELSGRAKDMGSAAVLIAIIVAVITWCILLWSHFG
>SEQF1516_EDU87052.1 redox-sensitive transcriptional activator SoxR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKKLPRIKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSGNQRRYKRDVLRYVAIIKIAQRIGIPLATIGEAFGVL
PEGHTLSAKEWKQLSSQWREELDRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN
>SEQF1516_EDU87053.1 phosphonate C-P lyase system protein PhnL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINVQNVSKTFILHQQNGVRLPVLNRASLTVNAGECVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAP
ARKVVEIRKTTVGWVSQFLRVIPRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWRLAPSTFSGGEQQRVNI
ARGFIVDYPILLLDEPTASLDAKNSAAVVELIREAKARGAAIVGIFHDEAVRNDVADRLHPMGASS
>SEQF1516_EDU87054.1 putative phnB protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLSPYLSFAGNCSDAIAYYQRTLGAELLYKISFGEMPKSAQDSAENCPSGMQFPDTAIAHANVRIAGSDIMMSDAIPSG
KASYSGFTLVLDSQQVEEGKRWFDNLAANGKIEMAWQETFWAHGFGKVTDKFGVPWMINVVKQQPTQ
>SEQF1516_EDU87055.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNGTIYQRIEDNAHFRELVEKRQRFATILSIIMLAVYIGFILLIAFAPGWLGTPLNPNTSVTRGIPVGVGVIVISFVLTG
IYIWRANGEFDRLNNEVLHEVQAS
>SEQF1516_EDU87056.1 maltose operon protein MalM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKMNKSLIALCLSAGLLASAPGISLADVNYVPQNTSDAPAIPSAALQQLTWTPVDQSKTQTTQLATGGQQLNVPGISGPV
AAYSVPANIGELTLTLTSEVNKQTSVFAPNVLILDQNMTPSAFFPSSYFTYQEPGVMSADRLEGVMRLTPALGQQKLYVL
VFTTEKDLQQTTQLLDPAKAYAKGVGNSIPDIPDPVARHTTDGLLKLKVKTNSSSSVLVGPLFGSSAPAPVTVGNTAAPA
VAAPAPVPVKKSEPMLNDTESYFNTAIKNAVAKGDVDKALKLLDEAERLGSTSARSTFISSVKGKG
>SEQF1516_EDU87057.1 fumarate reductase, cytochrome b subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELIFGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAA
LLHTKTWFELAPKAANIIVKDEKMGPEPIIKSLWAVTVVATIVILFVALYW
>SEQF1516_EDU87058.1 beta-lactamase precursor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGS
VSKTFTGVLGGDAIARGEIKLSDPATKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
GTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAETYGVK
STIEDMACWVRSNMNPRDINDKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDIIVNGSDNKIALAARPVKAITPP
TPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNYPNPARVAAAWQILNALQ
>SEQF1516_EDU87059.1 quaternary ammonium compound-resistance protein SugE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMALLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGE
SANPMRLASLALIVLGIIGLKLSTH
>SEQF1516_EDU87060.1 phage shock protein G [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLELLFVIGFFVMLMVTGVSLLGIIAALVVATAIMFLGGMLALMIKLLPWLLLAIAVVWVIKAIKAPKVPKYQRYDRWRY
>SEQF1516_EDU87061.1 sorbitol operon regulator SorC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENSDDIRLIVKIAQLYYEQDMTQAQIARELGIYRTNISRLLKRGRDQGIVTIAINYDYNENLWLEQQLKQKFGLKDVVV
VSGNDEDEETQLAMMGLHGAQLLDRLLEPGDIVGFSWGRAVSALVENLPQAGQSRQLICVPIIGGPSGKLESRYHVNTLT
YSAAAKLKGESHLADFPALLDNPLIRNGIMQSQHFKTISAYWDNLDVALVGIGSPAIRDGANWHAFYGGEESDDLNARQV
AGDICSRFFDIHGEMVETNMSEKTLSIEMNKLKQARYSIGIAMSEEKYSGIIGALRGKYINCLVTNSSTAELLLK
>SEQF1516_EDU87062.1 aspartokinase III, lysine-sensitive [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEIVVSKFGGTSVADFDAMNRSADIVLSDANVRLVVLSASAGITNLLVALAEGLEPGERFEKLDAIRNIQFAILERLRY
PNVIREEIERLLENITVLAEAAALATSPALTDELVSHGELMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDVA
ALAELAALQLLPRLNEGLVITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVDIWTDVPGIYTTDPRVVSAAKRI
DEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFVGSSKDPRAGGTLVCNKTENPPLFRALALRRNQTLLTLHSLNMLH
SRGFLAEVFGILARHNISVDLITTSEVSVALTLDTTGSTSTGDTLLTQSLLMELSALCRVEVEEGLALVALIGNDLSKAC
GVGKEVFGVLEPFNIRMICYGASSHNLCFLVPGEDAEQVVQKLHSNLFE
>SEQF1516_EDU87063.1 formate-dependent nitrite reductase complex, nrfF subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYKGLLTLLLLFTCFARAQVVDTWQFANPQQQQQALNIASQLRCPQCQNQNLLESNAPVAVSMRHQVYSMVAEGKSEVEI
IGWMTERYGDFVRYNPPLTGQTLVLWALPVVLLLLMALILWRVRAKR
>SEQF1516_EDU87064.1 hypothetical protein ECH7EC4501_0320 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHQLPCVTNFLSIISDEAGNSKGVRMIGYIGEETLATETASAV
>SEQF1516_EDU87065.1 cyclic diguanylate phosphodiesterase (EAL) domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNHRARHQLLALPGIIFLVLFPIILSLWIAFLWAKSEVNNQLRTFAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQ
KRMLNIIRGYLYINELIYARDNHFLCSSLIVPVNGYTIVSADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPL
FWSEVMSDDPTLQWGVYDTVTKTFFSLSKEASAATFSPLIHLKDLTVPRNGYLYATVYSTKRPIAAIVATSYQRLIAHFY
NHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQRALEKHQLCLYYQPIIDIKTEKCIGAEALLRWPGEQGQVMNPAE
FIPLAEKEGMIEQVTDYVIDNVFRDLGAYLATHADRYVSINLSASDFHTSRLIARINQKTEQYAVRPQQIKFEVTEHAFL
DVDKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVETLTTHKTSHLIAEHIIELAHSLGLKTIAEG
VETEEQVNWLRKRGVRYCQGWFFAKAMPPQVFMQWMEQLPARELTRGQ
>SEQF1516_EDU87066.1 formate-dependent cytochrome c nitrite reductase, c552 subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPAKPVTVEAKNETFAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWA
GYPFSRDYNKPRGHAFAVTDVRETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGC
ADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYFDGKNKAVKFPWDDGMKVENMEQ
YYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHGKNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQ
DKAALQKVVAERKQSINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHMHAPEEGLR
MLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQIKAEKQDFIKTVIPQWEEQARKNGLLSQ
>SEQF1516_EDU87067.1 hypothetical protein ECH7EC4501_0310 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFIFIIQLYNHFPVSLCFSENWSFIRTQEYMYEDLQRPTLYCFID
>SEQF1516_EDU87068.1 amino acid permease family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGAFYTRAEMKDGFMPHTIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAIPFYIFSALLFFIPFALMMAEMGAAYRK
EEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVSTSAKVWVPFSTFLYGSDMTQHWRIAGLEPTQVVGLLAVAWMILVT
VVASKGINKIARITAVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINFLASPNPGYQSGLAMLSFVVFAIFAYGGIEAV
GGLVDKTENPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGSVNLGNITYVLMKSLGVTLGNALHLSPEASL
SLGVWFARITGLSMFLAYTGAFFTLCYSPLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTVFILLVSFGGGTA
SAFFNKLTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTRMSAMIATVVVVLVVTFANVFTIIQPVVEAGDWDST
LWMIGGPVFFSLLAMAIYQNYCSRMANKPELALD
>SEQF1516_EDU87069.1 transcriptional regulatory protein DcuR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINVLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIFNSDTPIDLILLDIYMQKENGLDLLPVLHNARCKSDV
IVISSAADAATIKDSLHYGVVDYLIKPFQASRFEEALTGWRQKKMALEKHQYYDQAELDQLIHGSSSNEQDPRRLPKGLT
PQTLRTLCQWIDAHQDYEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTGRPVYRYRIQAEHYSLLKQYCQ
>SEQF1516_EDU87070.1 proton glutamate symport protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNIKFSLAWQILFAMVLGILLGSYLHYHSDSRDWLVVNLLSPAGDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRI
GAKTIIYFEVITTVAIILGITLANVFQPGAGVDMSQLATVDISKYQSTTEAVQSSSHGIMGTILSLVPTNIVASMAKGEM
LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVTVANFGFSSLWPLAKLVLLVHFA
ILFFALVVLGIVARLCGLSVWILIRILKDELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQ
SIAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVG
NALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ
>SEQF1516_EDU87071.1 hypothetical protein ECH7EC4501_0209 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKVLYGIFAISALAATSAWAAPVQVGEAAGSAATSVSAGSSSATSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ
>SEQF1516_EDU87072.1 hypothetical protein ECH7EC4501_0214 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFQRNIVDFSRIAGGWESPEWVIFELPALVRFVLPDAPPGAAYPAYG
>SEQF1516_EDU87073.1 nrfD protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQTSAFHFESLVWDWPIAIYLFLIGISAGLVTLAVLLRRFYPQAGGADSTLLRTTLIVGPGAVILGLLSLVFHLTRPWT
FWKLMFHYSFTSVMSMGVMLFQLYMVVLVLWLAKIFEHDLLALQQRWLPKLGIVQKVLSLLTPVHRGLETLMLVLAVLLG
AYTGFLLSALKSYPFLNNPILPVLFLFSGISSGAAVALIAMAIRQRSNPHSTEAQFVHRMEIPVVWGEIFLLAAFFVGLA
LGDDGKVRALVAALGGGFWTWWFWLGVAGLGLIVPMLFKPWVNRSSGIPAVLAACGASLVGVLMLRFFILYAGQLTVA
>SEQF1516_EDU87074.1 hypothetical protein ECH7EC4501_0283 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDSCEVVDISTPSQESKCKMSEAVHICHIAIFLHGA
>SEQF1516_EDU87075.1 PTS system, mannose/fructose/sorbose family, IIC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEISTLQIIAIFLFSCIAGMGSVLDEFQTHRPLIACTVIGLILGDLKTGIILGGTLELIALGWMNVGAAQSPDSALASII
SAILVIVGQQSIATGIAIALPVAAAGQVLTVFARTITVVFQHAADKAAEEARFRTLDILHVSALGVQALRVAIPALIVSL
FVSADMVSNMLNAIPEFVTRGLQIAGGFIVVVGYAMVLRMMGVKYLMPFFFLGFLAGGYLDLSLLAFGGVGVIMALVYIQ
LNPQWRKAEPQLLAPASTALDQLDD
>SEQF1516_EDU87076.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTISELLQYCMAKPGAEQSVHNDWKATQIKVEDVLFAMVKEVENRPAVSLKTSPELAELLRQQHSDVRPSRHLNKAHWST
VYLDGSLPDSQIYYLVDASYQQAVNLLPEEKRKLLVQL
>SEQF1516_EDU87077.1 metallo-beta-lactamase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNSRLFRLSRIVIALTAASGMMVNTANAKEEAKAATQYTQQVNQNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDAN
GKVYYRADDYKFDINAAAPETVNPSLWRQSQINGISGLFKVTDKMYQVRGQDISNITFVEGEKGIIVIDPLVTPPAAKAA
LDLYFQHRPQKPIVAVIYTHSHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISENVLAGNIMSRRALYSYGLLLPH
NAQGNVGNGLGVTLATGDPSIIAPTKTIVRTGEKMIIDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFY
TLRGAKTRDTSKWTEYLNETLDMWGNDAEVLFMPHTWPVWGNKHINDYIGKYRDTITFIHDQTLHLANQGYTMNEIGDMI
KLPPALANNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLHPYGQVEMGKRYVKALGGSARVINLAQEANKQGDYRWSA
ELLKQVIAANPGDQVAKNLQANNFEQLGYQAESATWRGFYLTGAKELREGVHKFSHGTTGSPDTIRGMSVEMLFDFMAVR
LDSAKAAGKNISLNFNMSNGDNLNLTLNDSVLNYRKTLQPQADASFYISREDLHAVLTGQAKMADLVKAKKAKIIGNGAK
LEEIIACLDNFDLWVNIVTPN
>SEQF1516_EDU87078.1 DNA-binding response regulator BasR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTA
RDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR
LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVANEEN
>SEQF1516_EDU87079.1 IS1203 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTSETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU87080.1 IS1203 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAVRMVLESQGEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGSGDGGLTTAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU87081.1 DNA repair protein, RadC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQQLSFLPGEMTPGERSLILRALQTLDRHLHEPGVAFTSTRAAREWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGT
INRTEVHPREVIKRALYHNAAAVVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGNQVFSFAEHGLL
>SEQF1516_EDU87082.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDITISRPEVVNGHTDVICSTSIRHILAVRKSTLLQIDTLIRQLAEISVLTESIGGKTAPDWAMKQDFRCGCWLMEKPE
TAMKAITRNLDREIWRDLMQRSGMLSLMDTQARDTWYRSLEYDNFPEISEANILSTFEQLHQNKDEVFERGVINVFRGLN
WNYKTNCPCKFGSKIIVNNLVRWDRWGFHLITGQQADRLADLERMLHLFSGKPIPDNRGNITLRLDDHIQSVQGKESYED
EMFSIRYFKKGSAHITFRKPELVDRLNDIIAKHYPDMLAV
>SEQF1516_EDU87083.1 hemagglutinin/hemolysin-related protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMINLSKEATVGKALTPIAILMMLSFPVASQAAGLVIKNGTVYNANGVPVVDINKPNGSGLSHNIWDNLNVDKNGVVFN
NSANESSTSLAGNIQGNSNLTSGSAKVILNEVTSKNPSTINGMMEVAGDKADLIIANPNGITVNGGGSINTGKLTLTTGT
PDIQDDKLAGYSVNGGTITLGKLDNASPTEILSRNVVVNGKVSADELNVVAGNNYVNAAGQVTGSVSATGSRNGYSVDVA
KLGGMYANKISLVSTEKGVGVRNLGVIAGGVNGVSIDSKGNLLNSNAQIQSASTINLTTNGTLDNTTGTVTSVGTISLNT
NKNTIVNTRAGNISTMGDIYVNSGTIDNTNGKLAAAGMLAVDTNNATLINSGKGSSVGIEAGLVALKTGTLNNSNGQIRG
GYVGLESAALNNNNGDIQTTGDIAIISNGNVDNNKGLIRSSTGHIVIGAAGSVNNGSTKTADTGSSDSLGIIADTGVEIG
ANNINNNGGQIASNGNVSLSSYSTIDDYAGKILSNSKVIIKGSSLRNDTGGISGKQGIEVAVGGSLTNNIGVISSEEGDI
SLLANSVDNHGGFMMGQNITMESMSGVNNNTALIVASKKLKINARGSIENRDGNNFGNAYGLYFGMPQQTGGMVGKEGIE
LSGQNIYNNNSRLIAEDGPLTLQAQNTFDNTRALVTSGADASIQVGGTYYNNYATTWSAGNLDIDATTLQNSSSGTMIDN
NATGFIASDKNLSLEVVNSLTNYGWISGKGDVDVTVNNGNLYNRNTIAAEKGLDIAALNGIENWKDISAGGDLTMNTNRH
VTNNSNSNMVGQNIVINAVNDINNRGNIVSDADLNVTTKGNLYNYLYMVGYGDIALSANSVANNNATIEATGDLIIDSKG
NVGNNRGNLHALNGVLSVKGNNLNNDNGEIRGYGDVTLALTGNYDSYKGSLTSETGDVTLTANIVDNAYGLIAGENVSVD
AKSTIYNNTALIAANKKLVINAGGNLENRDGNNFLRNNGALFGITDNVGGIVGKEGVTLSAQNVYNNNSSIIAENGPLNL
LSRGTLDNTRALLSSGADAIIRAAGTFYNNYATTYSAGNLDVYAASLNNASDGRLEDNTATGVIASDKNLDLSVDNSVTN
YGWISGKGDVHFNVLKGTLYNRNAIAADNALTINALNGVENFKDIVAGTALTIDTQKYVTNNSNSNMLGQTIAINAVNDI
NNRGNIVGDYSLGVKTTGNIYNYLNMLSYGVAGVSANKVTNSGKDAVLGGFYGLALEANETDNTGTIVGM
>SEQF1516_EDU87084.1 curli production assembly/transport component CsgF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVKHAVVLLMLISPLSWAGTMTFQFRNPNFGGNPNNGAFLLNSAQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQIL
GGLLSNINTGKPGRMVTNDYIVDIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF
>SEQF1516_EDU87085.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTITEIIGRVNTQLVDPMMVRWPLQELCDYYNDAVRAVILARPDAGASLETISCVPGARQVLPDGVIQLLDVICLSDGS
AVRPLSREVLDAQYPEWPTMKGIPECFISNDLSPRVFWLFPAPDKEISIDAVVSRIPEAVYVLTQDDDTPVPLEEAYVNP
LVEWMLFRAFSKDAAGGAESGLAAQHYQSFVEQLGIKQGADSALYARKKVFNGGGV
>SEQF1516_EDU87086.1 major curlin protein CsgA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLLKVAAIAAIVFSGSALAGVVPQYGGGGGNHGGGGNNSGPNSELNIYQYGGGNSALALQADARNSDLTITQHGGGNGA
DVGQGSDDSSIDLTQRGFGNSATLDQWNGKDSHMTVKQFGGGNGAAVDQTASNSTVNVTQVGFGNNATAHQY
>SEQF1516_EDU87087.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEKSIYLSSWALTEPDDIFYFYQPTWLNAWEAHMYERGLYGTRANGWGLKRFGVENDIYAPERIRNPQYMPYLEAMEQV
TDSALQQMPTKERMKLMKSRTAFIYADSWGESGSFEKISSALHIATIDTLPKNLLKKFSITEPTCKIRGEKQAFVQALRM
AQDYLAWDVFDNVVICAAYRAIPVLVFSEEDVGKPPKRLFPRRADEVNLSVERVGCFILSQRESAIRLQCGEYHSGTAPQ
HATDIDVMAFSERQQMPSRPAAGVIDLVAHYGESGCLTPALSMDYLTRHIQPGGKMRTVIADKQFGYHYFDLEYLEG
>SEQF1516_EDU87088.1 IbrA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDTLLTEKILTGENVLRAAIARIEWIFETFPSVCLSFSGGKDSTVLFHLVAEVARRRKRHFSVLFIDWEAQYRCTIEHI
QKMREMYHDVTETFYWVALPLTTVNGVSQFQPEWICWEPGVTWVRQPPEEAITDMTYFPFFRYAMTFEEFVPAFSSWFAG
NRCGVAVLTGVRADESLNRFMGLVSQRKLRYADDKPWTTASPEGFYYTMYPLYDWKARDIWIYNARACAIYNPLYDLMYR
ADVPLRNMRVCEPFGPEQRKGLWLYHVLEPETWARMCERVSGAASGALYANESGAYFALRKRISKPAHHTWRSYAMFLLD
VMPERTAEHYRNKIAVYLRWYQTRGFPDDIPDEQENDLGSRDIPSWRRICKTLIKNDFWCRPLSFSPNKPRHYERYLQRM
KERRKEWGIL
>SEQF1516_EDU87089.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLASRFGYANQIRRDRPLTHEELMRHVPSIFGENRHTSRSEHYAYIPTITVLENLQQEGFQPFFACQTRVRDQSRREYT
KHMLRLRRAGQITGQHVPEIILLNSHDGSSSYQMLPGYFRAICTNGLVCGQSLGELRVPHRGNVVDRVIEGAYEVVGVFD
RIEEKRDAMQSLVLPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWSAYQTIQENMLKGGISGRSAKGK
RIHTRAIHSIDTDIKLNRALWVMAETLLESMR
>SEQF1516_EDU87090.1 beta-ketoacyl synthase, C- domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNAAIISGYSVWMPYAEDCSQLIDNLKQGKRVARTPWFTSNEEAIKCGFKGNPSVATLKQVDDSALDLLSQLIDEALEQ
AMLDKHCLAGRNVRVYLTGIGPRIDGLDYKSFYNYNDVEDINLTQSITNLHASKMSQDTISSHLARKYRLQYLPPNMNCT
SNSSLTAVHLATQGIEQGGIDLAIVLNCSKIKTQDIWFLETQSMLDSEQVQPFGENSKGVAFAEGFSALLLESAHHRRAR
QQSEGVRVQTTYTQISAGRSNDASWLSTNVHKVMQAAMKQAEIALDDLAAILPHGNGSAVSDNAEAKAIAMFAGERQIPV
LAYKGQIGYTATGSGVVDLIIGHHSLTHHQLIAPVGNDVIIDSMASLVLTDGSVTNHSKRHLLKVGVGVDGSVIGVVMTN
MQAGRAK
>SEQF1516_EDU87091.1 glycosyl transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKRILFIGPPLYGLLYPLISLAQAFRVIGHDVVISSAGKFANKAAEAGLVVFDAVPGLDSEAGYRHQEELRKKSNIIGH
FSFFSDEMADNLIDFAGKWRPDLIVYPPLDPAGPLVAAKYRIPSVMLAVGFAHTSAHIQMLNRSLSNAYRRHGVSGPLCD
LAWIDVAPPSMSILKNAGEPVISMRYIPYNGGAVKETWWDRDSDRKRLLISLGTVKPMVDGLELISWVMDSANEVDADII
LQLAINARTGLRKLPSNVRLVDWIPMGVFLNGADGFIHHGGAGNTLTALYSGIPQIVFGEGADRSVNAEIVAKRGCGIIP
DKHGLTSDLVNRLLYDDSLRFCSDQVAAEMAEQPSPAEIAEVLMRKLKNNGKQL
>SEQF1516_EDU87092.1 putative purine permease ycdG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMFGLPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRV
PSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
IAVKSVSASGFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLGLGKAVDFTLVSHAAWFGLPHFS
TPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGRNMDPYMGRAFVGDGLATMLSGSVGSSGVTTYAENIGVMAVTKVY
STLVFVAAAVIAMLLGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTLVLGAGDFA
LTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVVHQEP
>SEQF1516_EDU87093.1 IS66 family transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISLPSGTRIWLVAGVTDMRKSFNGLGEQVQHVLDENPFSGHLFIFRGRRGDTIKILWADADGLCLFTKRLEEGQFIWPA
VRDGKVSITRSQLAMLLDKLDWRQPKTSRLNALTML
>SEQF1516_EDU87094.1 ISSd1, transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCQVFGVSRSGYYNWVQHEPSDRKQSDERLKLEIKVAHIRTRETYGTRRLQTELAENGIIVGRDRLARLRKELRLRCKQK
RKFRATTNSNHNLPVAPNLLNQTFAPTAPNQVWVADLTYVATQEGWLYLAGIKDVYTCEIVGYAMGERMTKELTGKALFM
ALRSQRPPAGLIHHSDRGSQYCAYDYRVIQEQFGLKTSMSRKGNCYDNAPMESFWGTLKNESLSHYRFKSRDEAISVIRE
YIEIFYNRQRRHSRLGNISPAAFREKYHQMAA
>SEQF1516_EDU87095.1 putative chaperone protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSVLLLLTILFVQSVEAGIMPASSRIIYRDGDREKTLMLVNTNDYPVLVQSWVDNGEGSPEAASPPFVVLPPVFRLAAR
RTQGLRIIYNHDPLPQDRESAFWLNLYEMPPETPHQDPTHLTLAMNTQLKIFYRPKSVTMTPQEAMRKISWHLGNDGSSS
YIELNNPTPLNISFTSISIGATKVQQESDMMIKPFSQRRYWLASNNVSGVVAATYLDDNGAQIKQQLAQ
>SEQF1516_EDU87096.1 hypothetical protein ECH7EC4501_3530 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFIPGKSFLLQIYIDKLAFDEKHTISMKCRMRQNFVMFFNSRKNKCGLLQNPVNVN
>SEQF1516_EDU87097.1 hypothetical protein ECH7EC4501_3565 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFFAIFSGCKFCIMAEPITFYVKKAVFIRIKQRYLRVLAAEKRVNTVI
>SEQF1516_EDU87098.1 immunoglobulin-binding regulator B homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGDSVTPEIIGNMIRQYFSQERPEEETIQALNHLRRVLHEVSPFAHEPVDCVLWVKADEVVANDYNPNVMAPGEKKLLKQ
SLEKDGFTQPVVVSEEKNHYLVVDGFHRQVLGREAGTGKRLKGWLPVVCINPERKGQASRIAATIRHNRARGKHQITSMS
DIVRDLSRLGWTNERIGTELGMDQDEVLRLKQISGLTELFQEEDFSPAWTVR
>SEQF1516_EDU87099.1 fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSTFKKAALLAAIALPFSTMAAPTVTFQGEVTDQTCSVNINGQTNSVVLMPTVAMADFGATLADGQSAGQTPFTVSVSN
CQAPTGADQAINTTFLGYDVDASTGVMGNRDTSSDAAKGFGIQLMDSSTSGNPVTLAGATNVPGLTLKVGDTEASYDFGA
RYFVIDSAAATAGKITAVAEYTLSYL
>SEQF1516_EDU87100.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRHPGNEYDQMTSDAAVDEAILINAYIFTETGQRAG
>SEQF1516_EDU87101.1 putative exogenous TonB-dependent siderophore receptor R4 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRITTLASVVIPCLGFSASSIAAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSSQYHDLAEALRSVEGVDVESGTGK
TGGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGFSAMNTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKN
ADKWLSSVNAGLNLQESNKWGNSSQFNFWSSGPLVDDSVSLQVRGSTQQRQGSSVTSLSDTAATRIPYPTESQNYNLGAR
LDWKASEQDVLWFDMDTTRQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHTFTFGTWKSYLNWNETENKGRELVRSV
LKRDKWGLAGQPRELKESNLILNSLLLTPLGESHLVTVGGEFQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALA
LTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPRMGQLHKGISGVSGQGKTNLLGNPDLKPEESVSYEA
GVYYDNPAGLNANVTGFMTDFSNKIVSYSINDNTNSYVNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNK
GAPLSYTPEHMVNAKLNWQITEEVASWLGARYRGKTPRFTQNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKMTDALT
LNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSSTTGYVIPERNYWMSLNYQF
>SEQF1516_EDU87102.1 IS66 family transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVELASQPGASVARIAREHDINDNLLFKWLRLWQNEGRISRRLQVTTSSDTGVELLPVEITPDEQKEPVAAIAPSLSTST
QTSVSAGSCKVEFRHGNMTLENPSPELLTLLIRELTGRGR
>SEQF1516_EDU87103.1 appr-1-p processing enzyme domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRAAGPALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAVVH
TVGPVWRGGEQNEDQLLQDAYLNSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYD
EENAHLYERLLTQQGDE
>SEQF1516_EDU87104.1 prophage CP4-57 Regulatory protein AlpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPLSKYYDATFPRPVRLGSGSVGWRSSAIDEWLTLHTVPARSAVKGVNDEVRHTLSSDMTMSR
>SEQF1516_EDU87105.1 transposase InsI for insertion sequence element IS30B/C/D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRTFTAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLRDTGGIKPHERKRAVAHLTLSEREEIRAGLSAKMSIRAI
ATALNRSPSTISREVQRNRKRTA
>SEQF1516_EDU87106.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGYGLLDIANQSRREALQGISDADRRREEIEAANKQMAAQQKAQNKQNIGTGIGTGAAIGASVGGPVGAVAGAVIGGIAG
SLF
>SEQF1516_EDU87107.1 rutC protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLFADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFI
TDWKNYAAINETYAEFFPGDKPARFCIQCGLVKPDALVEIATIAHIAK
>SEQF1516_EDU87108.1 IS1 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVCAEMDEQWGYVGAKSRQRWLFYAYDRIRRTVVAHVFGERTLATLERLLSLLSAFEVVVWMTDGWPLYESRLKGKLHV
ISKRYTQRIERHNLNLRQHLARLGRKSLSFSKSVELHDKVIGHYLNIKHYQ
>SEQF1516_EDU87109.1 hypothetical protein ECH7EC4501_3477 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVGYEKGKVYVKNTCVFFENTQQYQVIYVYTVRSKLT
>SEQF1516_EDU87110.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYYMKIYWTRKRIPELSALPPSLRKKNFTDAYNAASSHIEYWIGAGVSFISMMILSRVYDFLLPAQDTFPGDIIRSLCV
VCPSILIWFQFSVYVMRKYYRHILVRGKETETISERLIREADTREYELWRPVRRFFSIVFLIVLLGCIHSLITTIK
>SEQF1516_EDU87111.1 Tat-translocated enzyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQYEDKNGVNEPSRRRLLKGIGALALAGSCPVAHAQKTQSAPGTLSPVARNEKQPFYGEHQAGILTPQQAAMMLVAFDVL
ASDKADLERLFRLLTQRFAFLTQGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKM
TRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHAARSKGKETPINLLGFKDGTANP
DSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQFRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPE
GKGIALDSHIRLANPRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALEEYVKPIGG
GYFFALPGVKDANDYLGSALLRV
>SEQF1516_EDU87112.1 hypothetical protein ECH7EC4501_3626 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRSDASRCYSGNDNAVKKGEQYAPPNRKKIAIINEVI
>SEQF1516_EDU87113.1 hypothetical protein ECH7EC4501_3480 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIKKIKCADNDATSVVGGNMQIVVICLHCILRSVSYQT
>SEQF1516_EDU87114.1 TraT complement resistance protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTKKVMMIALVSSALALSGCGAMGTAIKKRNLEVKTQMSET
>SEQF1516_EDU87115.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADEECAQLVDLLQQTWSVISAGGQCRVERCFRVARPGSSGQYVALKTAVQSFMSQVIATIIR
>SEQF1516_EDU87116.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHEKNIALLCDEADRLLQLNINLLRQMVDEPDVLSDSKNENGLLFDKRKALKRIEELEGEQIKTARREMVLAVVGTMKAG
KSTTINAIVGQEILPNRNRPMTSVPTLIRHVPGKTEPVLHLEHIQPVRNLLITLQEKLATPAGQQVAQSLQQTGDTRELL
DILADDVWLKNEYHGEDEIFTGLASLNDLVRLAAAMGTEFPFDEYAEVQKLPVIDVAFSHLVGMDACQGTLTLLDTPGPN
EAGQPQMEMMMRDQLQKASAVLAVMDYTQMNSKADEEVRKELNAIADVSAGRLFVLVNKFDEKDRNGDGADAVRQKVPAM
LNSDVLPASRVYPGSSRQAYLANRALHELRKNGALPVDEAWVDDFIREAFGPMVEEDDWKDSTKVNKKAEKLWNISLIDQ
LITEVIQSSHSRAAALAVDSAAAKLMQNAENVSEYLSLRHQGLQQSIQSLQAHITSLLADIQEIEECQNQVTGDVRMAME
DINTKTGELLTKVCASLEEELNDYFRSGKRKEQQMLEEENSAQPRERNAFAFFHDIFGTGNQHDRMRDFDPDSPEIKFSD
RRAALELMTQIESTVTSLHREAEAQFRPELEKIVSGIETGFRGTALYATENIAGRINARLEDEGFTVKISFPAVSQLQTR
LAVKINLSALMEERTETVTRRRRQSGVWGTVCRWFGTSDLGWENYDEDVSRSVININKAREEVMSLTRAYFGELQASIEQ
DINQPVRQEIDAFFCAFREKVEQLRNTLIQSSEDHKRDQQAQERLTGRLQALNERVPELITDSKALREELETML
>SEQF1516_EDU87117.1 glucans biosynthesis protein C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPL
KKWWKVRVERVGIPMLTAIPLLTLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGTFNFIVMQTLFYLPFFILGALAFIFPHLKALF
TTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHH
PLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR
>SEQF1516_EDU87118.1 tellurium resistance protein TerD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVSLSKGGNVSLSKAAPSMKNVLVGLGWDARSTDGQDFDLDASAFLLASNGKVRGDSDFIFYNNLTSSDGSVTHTGDNR
TGEGDGDDESLKIKLDAVPSEVDKIIFVVTIHDAQARRQSFGQVSGAFIRLVNDDNQTEVARYDLTEDASTETAMLFGEL
YRHNGEWKFRAVGQGYAGGLASVCAQYGINAS
>SEQF1516_EDU87119.1 putative aminomethyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSLAEFHLKNNAVMGVYNNRTLPSSYHDAMTEYKAVRENALLVDYSHLSIVSVMGDDAWALINQLVSADVSIIRDEQAI
YSLVLNEEGTIRGDVYVLCSIDGYYLLSEDISAAELIASMNTILEKAEELDIQSMPEIQDMRENNWGAILLEGPYSWEIM
SEIHGFDVIGLPYYEYMNTEEDLLLFRCGKHGEYAYMTIGEQAKLAEQWEKLLTVGEKYLMQTGGLDYQKIVRLENPCWD
ASLWEGQAVNPVQLQMQWAVQYDKDDFIGKDAVTELSQEYTGNKLIGMIAQEECEGIEAGDRVLVEGQDVGYVVKALFSP
ALQRFIALTLLEKDYAWSDISGYEIQTAHGIIPAQSKCMPFIYNLSMLVSPTEHSYIDASKNKSAA
>SEQF1516_EDU87120.1 outer membrane protein Lom [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSIATLVVCAISGIACVNLSAHAAEGEHTISLGYAHFQFPGLKDFVKDATAHNRETFSHFVNRNYFSSLGEYTDGRVSG
YEGKDKNPQGINIRYRYEITDDFGVITSFTWTRSLTNSQTFIDVQSADHTRKIKNPAASARTDIRANYWSLLAGPSWRVN
QYMSLYAMAGMGVAKVSADLKIKDNINSSGGFSESNSTKKTSLAWAAGAQFNLNESVTLDVAYEGSGSGDWRTSGVTAGI
GLKF
>SEQF1516_EDU87121.1 urease accessory protein UreF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTPEKRLRLMQLASNSLPVGGYSWSQGLEWAVEAGWVEDSAAFEHWQQLQMEQSFFAVDLPLLARLYRACEAGDPDSAG
RWTAYLLACRETRELRDEERNRGAAFTRLLVDWQPDCPAEWRKLCQQSQLTGMAWLGVRWQISVSDLALSLGYSWIESAV
MAGVRLVPYGQLAAQQLIMRLCARYAANMDSALATPDHAIGSATPLASIASARHETQYSRLFRS
>SEQF1516_EDU87122.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNAIACSSSLVIVCTWEAIYRSTSHYGKNVLLLQLA
>SEQF1516_EDU87123.1 biofilm PGA synthesis protein PgaD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLLTGYYWQSEARSRLQFYFLLAVANAVVLIVWALYNKLRFQKQQHHAAYQYTPQEYAESLAIPDELYQQLQKSHRMSV
HFTSQGQIKMVVSEKALVRA
>SEQF1516_EDU87124.1 TerA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLTPGGNAPVPAQELRVRITSGGQVDASAFRLYADGKVQGDADMVFYGQPRNDDGTVSLVSEGQYSTFTVALNRLKPDV
QKIAFTVTCDGGQTVSGLRNLSIDVEQGATGLVSGSVELSGRQEAALILGEFYRRNNDWKFRFVAQGFNGGLKPLAEHFG
VNIADEPAPAAPTPPVVTPPPVETKISLSKVSLTKEKPAISLTKRDNFGEIRINLNWHRGSSKSGFAGMFGSKGIDLDLG
AFVELQDGYKSVIQALGNAFGDYRDEPYVQLKGDDRTGDVSDGEWLHINGREWKHIREVLIYAFIYEGVPSWDKTDGVVT
IHVPDQPPIETRLTEGENRRTLCAIARLVNENGAIKVERINQYFKGQDEMDRAFGWGFRWSAGSK
>SEQF1516_EDU87125.1 diguanylate cyclase (GGDEF) domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTVQFLYLLIIERDLQPTDWCSFMEKDYLRISSTVLVSLLFGLALVLVNSWFNQPGVEEVVPRSTYLMVMIALFFIDTV
AFIFMQLYFIYDRRQFSNCILSLAFLSCLIYFVKTVIIIQQIIEGRLTSSVVQNDIAIYYLFRQMSLCILIFLVLVNKVS
ENTKQRNLFSKKMTLCISLFFVFGGAIVAHILSSHYESYNLHIAELTNENGQVVWKASYVTIMIFMWLTLLSVNLYFNGL
RYDIWNGVTVIAFCAVLYNISLLFMSRYSVSTWYISRTIEVVSKLTVMVIFMCHIFSALRVTKNIAHRDPLTNIFNRNYF
FNELTVQSASAKKTPYCVMIMDIDHFKKVNDTWGHPVGDQVIKTVVNIIGKSIRPDDLLARVGGEEFGVLLTDIDTERAK
ALAERIRENVERLTGDNPEYAIPQKVTISIGAVVTQGNALNPNEIYRLADNALYEAKETGRNKVVVRDVVNFCESP
>SEQF1516_EDU87126.1 ATP/GTP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNRLSPWNLGATLYMPATREDIADAVLHGKIPGLRSLVICLEDAVSEADIPVALKNLEHLLHELSNSMSSLGKNDWPLV
FIRPRHAEMGRWLKAHYDLSAVDGFVLPKFTLSSLAEWWDIMVGTHLCMMPTLETEDVFDVVQMRELATRLEEHPCHDRI
IALRIGGNDLMNVVSLRRPRDLTLYDSPMGYVIKMLVSVFGPRDFALTAPVCEHIDDHAVMARELALDMAHGLVGKTAIH
PGQIEVIQNALMVTQGEHSDALRILNSTQAVFKSQGAMCEPATHRRWAAGILDRARFYGLQNEQSADGIRLLTVTQHH
>SEQF1516_EDU87127.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSPEQYLSSSEPASDTSLAVAPAQQNKSTIVRLRSFVCIADDAPEKRVNMSSPEYY
>SEQF1516_EDU87128.1 biofilm PGA synthesis protein PgaA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLLTAAFLAASPAAKSAVNNAYDALIIEARKGNTQPALSWFALKSALSNNQIADWLQIALWAGQDKQVITVYNRYRHQQ
LPARGYAAVAVAYRNLQQWQNSLTLWQKALSLEPQNKDYQRGQILTLADAGHYDTALVKLKQLNSGAPDKANLLAEAYIY
KLAGRHQDELRAMTESLPENASTQQYPTEYVQALRNNQLAAAIDDANLTPDIRADIHAELVRLSFMPTRSESERYAIADR
ALAQYAALEILWHDNPDRTAQYQRIQVDHLGALLTRDRYKDVISHYQRLKKTGQIIPPWGQYWVASAYLKDHQPKKAQSI
MTELFYHKETIAPDLSDEELADLFYSHLESENYPGALTVTQHTINTSPPFLRLMGTPTSIPNDTWLQGHSFLSTVAKYSN
DLPQAEMTARELAYNAPGNQGLRIDYASVLQARGWPRAAENELKKAEVIEPRNINLEVEQAWTALTLQEWQQAAVLTHDV
VEREPQDPGVVRLKRAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYSPPLKDNWRGFAGFGYADGQFSEGKGIV
RDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDNWRIGSQLERLSHRVPLRAMKNGVTGNSAQAYVRWYQ
NERRKYGVSWAFTDFSDSNQRHEVSLEGQERIWSSPYLIVDFLPSLYYEQNTEHDTPYYNPIKTFDIVPAFEASHLLWRS
YENSWEQIFSAGVGASWQKHYGTDVVTQLGYGQRISWNDVIDAGATLRWEKRPYDGDREHNLYVEFDMTFRF
>SEQF1516_EDU87129.1 putative outer membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEYGFAIYNRNNVNVTGVLTPVFFLDRFTAESGSKTYTNKPDGKSLQAVCCLFPWNNVFADRKVPKITINDNTVTWSNLE
QGMGSYIYTFWG
>SEQF1516_EDU87130.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPDYLTFIRFQDKRSLIYIYAIGLILIGFYWKNAGFTFPSEDIGVVSGILALVLYNFIFDLKAYWAYKCVTKNIDFSWF
KKKQNHKIELFLTQPLVAGFLSLIMLSAMSWGLYQRLPSLYALFLISLLGPLVIFLLFRMIRTSYVKQVAISVAKKVKYK
SLTRYVLLSVCISTVVNLLTISPLRNSDSFVIEGQWLTFKSIIALLILCGVVLAINLFFLRFSRRYAFLGRLFLQEIDLF
FSSENALSTFFAKPLWLRLFILLVIEVMWITLVSVLATLVEWRIWFEAYFLLCYVPCLIYYFFYCRFLWHNDFMMACDMY
FRWGHFNK
>SEQF1516_EDU87131.1 transcriptional regulator CsgD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQRSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNN
NIKILLLNTPEDYPYRDIENWPHINGVFYAMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR
>SEQF1516_EDU87132.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGFRFRKSINIIPGVRLNLSNGAPSLSVGPRGASVSFGSRGTYANLGLPGTGLSYRTRLDRAARSRGENRTATDPGLRQA
LEQKAAELMSAVTAIRNIHELTPDPKTGISWAELEAVYLHNRTSPFQVPAPVRPEKPDYLVLPEKPAESEGISFLGKWFE
SESAKAERHAENLRRWQQELIDVERENTLRQHRYQQQRTAWAEQYANWKFEAEEHEKRLATAQADARQQFRTDAAFFESY
LAGVLAETEWPRETLVAFEVKPELSAVLLDVDLAEIEDFPDKIYGVNARGTELTEKAMTQKAVRENYAHHVHGCLFRLVG
IVLHTLPFDNVIVSGFTQRVSKRTGYLEDEYILSCKCTRSQMSSVNFAGIKHIDPVEALGDQPVIRKMSSTFIFQPIEPL
TL
>SEQF1516_EDU87133.1 integral membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKKISINFLFLMLMIDVVFATLFNIPVWMHLFNIINNLDGVKLGFIISLPVFLISALNFVFTPFSFRYIFKPFFCILFI
CSSIVTYATMKYGVQFDKTMMQNIFETNAGEMTSYFNMSVVLWFLFTGILPCGLLLLVNIRYPETWIKGITYRLISMFAS
LLIIFAIAFFFYKDYASVGRNNSSLNKEIIPTNYIYSGFKYVRDFFVSPGEFRQTGTDASRTINEKQKPVIMFLVVGETA
RSQNYALNGYSRGTNDFTKKYNELISFHNVQSCGTSTAISVPCMFSDMKRKEFNSRKAVNSENVLDILYRTGVNLLWIEN
DGGCKGVCKRIPTINIEPSNSDNTLCKKNSCYDEVMLKNIDEYINNNSEDKLIVFHLMGSHGPTYYLRYPESHKYFKPTC
DRSDIENCTHEQLINTYDNTIRYTDYIISKLIDKLIEYKDEYDTVLLYVSDHGESLGENGLYLHGTPYNVAPAEQTHVPL
ITWMSPGFVSSKKIDLNCLSEHALNRTVSHDNIFSSLLGLWNVNTSVYNKEDDIISSCR
>SEQF1516_EDU87134.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKSTFLHILISSIILVALIQSSAWANCTNTQIGQTEDGRTALIEFGKINMTDTYFAPAGSLLATTVVPPTNYTSGGATG
SSVLWECDATDLPNIYFLVATNGDDRVGGFYDAGGPDGLSDVYATWFAFVGLKQTMAGVTLGRYWKKVPITSYATQGTKI
QIRLQDIPPLHAELYRISTLPDTSATTSWCGNNNTDSSGVGFAKPSGTIYNCVQPNAYIQLSGTSGILFGHDEPGEDSSV
HWDFWGADNGFGYGMRSANRLYNNATCVARSATPLVLLPTIAEAQLNAGMESTGNFNVRVECSNSVQSGISDTQTALGIQ
VSEGAYTAAQKLGIINSNGGVSALVSDNYDAAEMAKGVGIYISNSAHPDTAMTLVGQPGIAKLTPGGNAAGWYPVFEGAT
LEGATHPGYSSYSYSFIARLKKLPNQTVSAGKVRATAYILVKMQ
>SEQF1516_EDU87135.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEDVPLPKVNQRYKDDHGALVTLTSVEETRVVFMQDGYPHPCMRPMYNFLGKFKPEPREETE
>SEQF1516_EDU87136.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQKSLITVTICMTVIFTIWMLHGSLCEFRLNLWGAEFAAFLQCKQ
>SEQF1516_EDU87137.1 hypothetical protein ECH7EC4501_3526 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKTNIRIIQTKTHWKGIIFYITRKSGSLLSFYLYLSGA
>SEQF1516_EDU87138.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQLTFLKGATAKNVRECNLMKNSVAEH
>SEQF1516_EDU87139.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKLALTLEADSVNVQALNMGRIVVDVDGIELAELINMVCDNGYSLRVVDESDQTSAECTPPFATLTGIRCSTAHITETD
NAWLYSLSHQTSDFGESEWIHFTGNGYLLRTDAWSYPVLRLKRLGLSKTFRRLVVTLIRRYGVSLIHLDASAECLPGLPT
FDW
>SEQF1516_EDU87140.1 ISSfl3 OrfC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDISLLSTTSDPEQLRALAIAMVQKVMAENAELQNRIRILEEQMKLARQQRFGKKCESLAGMQRSLFEEDVDADIAEISA
HLDKLLPQTGDEEKTTTRPVRKPLPSPLPRAEKVIPPAEERCPDCDAPLHFIRDEVSEKLEYIPAQVVVNRYIRPQYSCP
CCEKVFSGKMPAHILPKSAVEPSVIAQVVISKYTDHLPLYRQQHIFSRMGVELPVSTMADMVGVAGAALAPLAKLLRHEL
LTRDVIHADETSLRLLDTRKGGKSCSGWLWAYVSGERVSVNGAPY
>SEQF1516_EDU87141.1 transcriptional regulator RutR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAP
LKAFREDFAPLAAIKEYIRLKLEVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKSLIDEKSALIAGWVKSGKLAPIDPQ
HLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR
>SEQF1516_EDU87142.1 TerW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLNTRQARIFKLANLLGTGKPVSAADIITSLECSEPTLTRALKELRESYSAEIKYSKAGHSYHLVNPGQLDKKTLRRMN
EALAQNAELKTGESTGKVVLDKDKKTAVSLSLRMRILRKIDRLAALSDSTRSEAVEKLALHSVDELIKEYSAKKS
>SEQF1516_EDU87143.1 hypothetical protein ECH7EC4501_3485 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLAENPRQGMTTEARVVIRILLISDHVNRQDNTQIQTIMRIIYICLLQKIKIIDKTKYK
>SEQF1516_EDU87144.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFRPFLNSLMLGSLFFPFIAIAGSTAQGGVIHFYGQIVEPACDVSTQSSPVEMNCPQNGSVPGKTYSSKALMSGNVKNAQ
IASVKVQYLDKQKKLAVMNIEYN
>SEQF1516_EDU87145.1 putative GTPase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTSHEPVIGIMGKSGAGKSSLCNALFQGEVTPVSDVHAGTREVRRFRLS
GHGHSMVITDLPGVGESRDRDAEYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILHRGHQQVLFVVTQADKTEPC
HEWDMAGIQPSPAQEQNIREKTDAVFRLFRPVHPVVAVSARTGWELDTLVSALMTALPDHAASPLMTRLQDELCTESVWG
QAREQFTGAVDRIFDTVESVCVASVARTVLRAVRDTVVSVARAVWNWIFF
>SEQF1516_EDU87146.1 2-deoxy-D-gluconate 3-dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFSIEDFSLDFFSLHNKVAIVTGAAGELGRGLCSALAKAGANLLLVDIKEPDNRYLKHLTHEGVEVEFMTIDITKPDAS
CTIINRCLERFGQLDILVNNAGVCNINRPIDFNRNDWDPMINLNLNAAFDMSQAALNIFVPQRKGKIINMCSVLSFHGGR
WSPGYAATKHALAGLTKAYADDFAEYNIQINGIAPGYYVSEMTAIIYNNPKIKELIKGRIPAQRWGRAQDLMGAMVFLAS
AASDYVNGQLLVIDGGYSIR
>SEQF1516_EDU87147.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAELSDFLPYVRRHISGPLNIMMTDALSMAAVAFSRQSLVCRREVTVVPVAGKEIVLPYDKDDEECVHIIRISDDNHELF
VGRDVDISSGRSLRFACSPGEVSVLYAVAPKAGRSQIPDELLTWPEEVAAGALERLFMQTGVSWSDPLRAQYFSVQFSEG
IRRAYRHTLATSPYSSYRNPVRRQRFF
>SEQF1516_EDU87148.1 hypothetical protein ECH7EC4501_3424 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPVVIAIERSMFMPRMIAENAAMNEIEHTFYATANYLLQL
>SEQF1516_EDU87149.1 phopholipase D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRLASAVLPLCSQHPGQCGLFPLEKSLDAFAARYRLAEMSEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLD
DNNTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVVTLVGGRNIGDAYFGAGEEPL
FSDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDVPEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTL
PLIWAKTRLLSDDPAKGEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAILTNSLAAND
VAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKTFSIDGKTVFIGSFNFDPRSTLLNTEMGF
VIESETLAQLIDKRFIQSQYDAAWQLRLDRWGRINWVDRHAKKEIVLKKEPATSFWKRVMVRLASILPVEWLL
>SEQF1516_EDU87150.1 putative rutE protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEAVSPGALSTLFTDARTHNGWRETPVSDETLRELYALMKWGPTSANCSPARIVFIRTAEGKERLRPALSSGNLQKTLT
APVTAIVAWDSEFYERLPQLFPHGDARSWFTSSPQLAEETAFRNSSMQAAYLIIACRALGLDTGPMSGFDRQHVDDAFFA
GSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL
>SEQF1516_EDU87151.1 glucans biosynthesis protein G [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHKLQMMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPKSNLPSVFRDMKYADYQQIQFNHDKAYWNNL
KTPFKLEFYHQGMYFDTPVKINEVTATAVKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGA
SYFRVIGAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAYKFVVMPGRDTVVDVQS
KIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNGLSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQ
RGRDFSRFEDLDDRYDLRPSAWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDEDKL
HAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTSIGDNGEIVESTVRYNPVTKGWRLV
MRVKVKDAKKTTEMRAALVNADQTLSETWSYQLPANE
>SEQF1516_EDU87152.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPQKTIIVGMLCLTMLLTVWVLHASPCEFRVSFMWSEIAAFLQCKP
>SEQF1516_EDU87153.1 MchS1 protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESNLTVYTGGHDYAWWRGAIIDELANYNCRKVSNNNSV
>SEQF1516_EDU87154.1 phospholipase, patatin family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTEMKTGLVLSGGGAVGAYQAGVVKALAECGTQISMVSGTSIGAFNGAIIAASPDLSEAAVRLEALWEHLGNNQVLSVN
RLVYFSLLKKLFQAMNLCQIPGRAGALLTTLLRHISTINGFDNLMAQPLLSDEPLTALMDHYLDTDALADGLPLYVSLYP
TEGGMQDIIDCIRAELGVGTTKNAVFQHIQSLPRGQQKEALLASAALPLLFRPREVQGTMFGDGGMGGWRNMQGNTPVTP
LVDAGCNMVIVTHLSDGSLWDRQAFPDTTILEIRPRKRLKYAGDGGNSGGLLSFTSAHTDAWRQQGYEDTMLAMEHIRKP
LAARQALTRSEAVLQKSLDITEEADLALRNAMARIK
>SEQF1516_EDU87155.1 large subunit terminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEAEQRLFIMTKLSNPWWRLNHLYKIQNEKGELVTFRMRPAQRQLFRSMHNKNIILKARQLGFSTAIDIYLLDQALFIP
HLKCGIVAQDKQAASEIFRTKIAVPFDHLPDWLRASFTIVERRSGASGGYILFGHGSSIQVATSFRSGTVQRLHISEHGK
ICAKYPAKAKELRTGTLNAVSDECIIFDESTAEGVGGDFYEMSNRAQEITASGLLLTAQDYKFHFYAWWQDPKYSARVPE
SGLKLSREKMTYFSAVEKAMNITLTDEQKQWYINKETEQREEMKQEFPSTPQEAFLTSGRRVFSAESTLQAESFCSPPMI
VYDIEPVTGAKTKAQSLREGNKNELQRTLMNYLLVWELPDPDEEYVCGADTAEGLEHGDRSSLDVVKRSNGEQVAHWFGH
LDAELFAHLISQVCRMYNNAFVGPERNNHGHAVILKLRELYPTRYIYNEQHLDQAYDDDTPRLGWLTTRQSKPVLTEGMK
TLLNNGISGIRWSGTLSEMNTYVYDAKGSMNAQEGCFDDQLMSYMIAQEMRARMPVRVKQKTDKRRTTHWMAH
>SEQF1516_EDU87156.1 urease, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSWRQMMSNISRQAYADMFGPTTGDKIRLADTELWIEVEDDLTTYGEEVKFGGGKVIRDGMGQGQMLSAGCADLVLTNAL
IIDYWGIVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGVSTEIIAAEGRIVTAGGVDTHIHWICPQQAEEALTSGITTM
IGGGTGPTAGSNATTCTPGPWYIYQMLQAADSLPVNIGLLGKGNCSNPDALREQVAAGVIGLKIHEDWGATPAVINCALT
VADEMDVQVALHSDTLNESGFVEDTLTAIGGRTIHTFHTEGAGGGHAPDIITACAHPNILPSSTNPTLPYTVNTIDEHLD
MLMVCHHLDPDIAEDVAFAESRIRQETIAAEDVLHDLGAFSLTSSDSQAMGRVGEVVLRTWQVAHRMKVQRGPLPEESGD
NDNVRVKRYIAKYTINPALTHGIAHEVGSIEVGKLADLVLWSPAFFGVKPATIVKGGMIAMAPMGDINGSIPTPQPVHYR
PMFAALGSARHRCRVTFLSQAAAANGVAEQLNLHSTTAVVKGCRTVQKADMRHNSLLPDITVDSQTYEVRINGELITSEP
ADILPMAQRYFLF
>SEQF1516_EDU87157.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKTILAPSLSERVYTGTHGNESVAEGVFTVNAAEADSVIHLLSLPVGIRINSLQLVSTGGLGTATVSIKSGEHALIDNS
EAVSAKFARYVPVEPYTTQRDGELVTVTIKTAAATGTLNVLLRYTVVGY
>SEQF1516_EDU87158.1 chaperone, TorD family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEFSILCRVLGSLYYRQPQDPLLVPLFTLIREGKLAANWPLEQDELLTRLQKSCDMTQVSADYNALFIGDECAVPPYRS
AWVEDATEAEVRAFLSERGMPLADTPADHIGTLLLAASWLEDQSTEDESEALETLFSEYLLPWCGAFLGKVEAHATTPFW
RTMAPLTRDAISAMWDELEEDSEE
>SEQF1516_EDU87159.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEILRIAQTYEPWLDFWELVVQNVSTIASHTATNRPLPEAIMANYQLDEQLLEGCRP
>SEQF1516_EDU87160.1 acidic protein MsyB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTMYATLEEAIDAAREEFLADNPGIDAEDANVQQFNAQKYVLQDGDIMWQVEFFADEGEEGECLPMLSGEAAQSVFDGDY
DEIEIRQEWQEENTLHEWDEGEFQLEPPLDTEEGRAAADEWDER
>SEQF1516_EDU87161.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTRIDYLADKYCFTERNESPRLRRQWQDVLEECRQTEAGPEERLRIALLNVDYVTSFELPFRLLLTRTPQLIAALREEW
GISQKNVVFNDKRFGCVYSLKASLSGVPDTYRYHLSHRIRRVVGNENTSLPYQQVAREVKAPRERLKYALEAGLLVTALD
GLFRFGSQRIAADVLRLRKAGMPVVTTTVEVHDNLTGTTRKVPAYHL
>SEQF1516_EDU87162.1 IS66 family element, orf2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPS
ARDGKVFLTQAQLAMLLEGIDWRQPKRLLTSLTML
>SEQF1516_EDU87163.1 oxidoreductase, short chain dehydrogenase/reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMYKYNDLNEKTVLVTGASGDIGLGICEKYLEQNCDVYALYKSNDVQLTALKASHPAGDKLHIVQCDLACPQSVSALCE
QIERQAGKIDVLVNNAGIVKDSLFASMSYEDFTQVIETNMFSIFRLTKDALMLLRAAENPAIINVASIAALIPSVGQANY
SASKGAILGFTRTLAAEMAPWGVRVNAVAPGMIESKMVKKVSRAVVRAVTSTIPLRRLGKCEEVANTIVFLSSSASSYIV
GQTIVIDGGLVMR
>SEQF1516_EDU87164.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYNFITIMYDVFSCFGVLAKNQNSRDIRNIKNFSSHQHSLGDMFDELINIIDKEQVLSKEQRKVIFRRYEDLYVKLMHYS
VFTDKTHQIIKQKYFNDIVPMILALDIRNTYRPDNEMAFYYHIHSFLTQIPDNEDDIYHAARTYLRNYVKLCLSGYTPAN
AHFKDIFDGVYEFIRNIRKNSTPGKTKLIATINTCKETCKHLLYLSNEDKEKIISDLDKVQVACYYLTILLAFERRTSLT
STLATLYKMLISEREVSEYECQLLYLTNPIDVMNILNKYIYYFPNENSPFYTLKIDSALSWDAIDAIRDYSISDIYLYPE
QKTINCVVEIENIVFGGYIYTLNNGVTLQNIENSLKDSSCHYVLNGYTEFVNCLRQLTSGKTESVHRTINKLNYEKLPFG
FIIAAFAILKIAFKIKFSKNHVNIRALLNDINYFMTYQGESINLISLDHEYPESCLQNDTNTYLLGRVIFLYNSMIYKFI
NCQEHETNNIHSAMINNLLQEVDIALGKINDIIDSRNISAPHELANILTREKILTTREKKGNLISLFDGFTLFHCVGMIT
FLIHYLRTPEEKVENIFMLYGADKNNKLRRRLIYDALGIIQSQQE
>SEQF1516_EDU87165.1 complement resistance protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSPDKAYYWIQANVLKADKMDLRESQGWLSRGYEGAAVGAALGGGITAYNTGSAGTTLGVGLATGLIGMAADAMVEDIN
YTMITDVQIAERTRTSVRTDNVAALRQGTSGSKIQTSTETGNQHKYQTRVVSSANQVNLKFEEAKPHLEDQLAKSIANIL
>SEQF1516_EDU87166.1 putative flavin reductase rutF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTDTPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEP
LSNLFGGKTPMEHRFAAARWQNGVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALM
RPAC
>SEQF1516_EDU87167.1 lipoprotein-releasing system ATP-binding protein LolD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSTIKSLPAISLSNIYKCYGAGAGKVDALKSINLDINKGEFLALCGPSGSGKSTLLNILSGIDKPTSGTVIFLNKLLNQ
LPEEQLAVIRGKHLGFIFQFFNLMPVLNVFDNVYFPLVLNGQFSKKEATERTLHYLDSVGLSGFGDRKPGQLSGGQQQRV
AIARALAHEPMVVIADEPTGNLDLATGEAILDLLLTINQQTGTTFVISTHSSELKARARRVVEIQDGVLIHDSDA
>SEQF1516_EDU87168.1 diacylglycerol kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANTTTGVTRIIKAAGYSWKGLCAAWRYEAAFRQECILVLSALIISFWLDVDSVTRVLLIGSAMMVIIVEIINSAIEAVV
DRIGSEHHELSGRAKDMGSAAVLITILVAIIIWGVLLLS
>SEQF1516_EDU87169.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLAGQVLITLITWRSHVSGSIPLSFAATDQAVHHCRTIARHLKVLSRQQEGIILSRHFSRGPVR
>SEQF1516_EDU87170.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMFTPYRRGTIPAIRIADGTIQAHDDIDEEFFQPVLDGFLISKYTPFDILHALKDGVLQRTG
>SEQF1516_EDU87171.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLVNTHGFTTGDDSHDVIPLKTEDKSENRCDVVVTG
>SEQF1516_EDU87172.1 sodium/proline symporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGPFVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAI
GLTLGAWINWKLVAGRLRVHTEYNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSY
ETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGFGDSLEVIKQKSIENVDMLKGLNFVAIIS
LMGWGLGYFGQPHILARFMAADSHHSIVHARRISMTWMILCLAGAVAVGFFGIAYFNEHPSVAGAVNQNAERVFIELAQI
LFNPWIAGILLSAILAAVMSTLSCQLLVCSSAITEDLYKAFLRKHASQKELVWVGRVMVLVVALVAIALAANPENRVLGL
VSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFGWLGLYEIIPGFIFGSIGIVVFSLLGKAPSAAM
QKRFAEADAHYHSAPPSRLQEG
>SEQF1516_EDU87173.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQPHETFTGSYQPGDVEFLLKPVVIEMTPVEKKEELIQSGKKHYSDMLSQEPAPTQWHLDLFHRALDRGAERLAKEVTQL
AIALAERFGDEPIVLASLVRAGVPLGVMLHQALRDMGKTSWHYGISIIRDRGIDGAALDVIEERHGTSGIVFVDGWTGKG
AITGELVRALKDRPGYPEQPRLVVLADPCGCSWLAASDDDWLIPFGIMGAPVSGLISRSVWSSEGLHGCMVCEHLSEFEC
SRMLADTVAHFRKKLTPSSLAPLSWNTESARVLWQTSRDVIAFLADEFKVDSVNRIKPGIAEATRAVLRRVPDHVFVRSI
DDPDVALLVGLAREKGIVVTEMGGTLGQYRAVTIIKKVL
>SEQF1516_EDU87174.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQRYFLFAGIILCAFIAAILSHIAFHHANEPAEQNISCNAHVINFTDHTKMDQYFSLNMISENNTGNMYLTGAYTVDGK
KIGFIRRYVSFTYKKFRDTVYFTTVKIQKIQKDDNISDEILENITSDFFIKVDTSINFYVTRQNDYNYVFSTGRTPRFIC
ISH
>SEQF1516_EDU87175.1 urease, gamma subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELTPREKDKLLLFTAALLAERRLARGLKLNYPESVALISAFIMEGARDGKSVAALMEEGRHVLSREQVMEGIPEMIPDI
QVEATFPDGSKLVTVHNPII
>SEQF1516_EDU87176.1 potra domain, shlb-type family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSLTLMSALLSPLSLQAADVRRSGDEAFIIQQQRQEALEQQLTPSAPDVRLSAPGSFAHKINFPVETPCFQIKQTELKG
ADALPHWLPLQKIANGAVGHCLGAKGINLLMSTLQNRLVDHGYVTTRVLAPSQDLKSGILRLVIIPGVVRHVRLTPDSDD
YIQLYSSFPAHEGSLLDLRDIEQGLDLGNSRIQGQHTELNATSGNLSTQNAQLSADTLSARTAGQFSSNGGTINADTLQI
SAQSLSNRKGSLIQTGTGDFSLSLPGSVDNREGLLAANGAVRLDALSLDNRKGKVQAEQSPSLQKSPPTFLKPFVAGVCA
ALLAVSVAIPGWQFLTQPSPEEQHFTWGNGCKKQ
>SEQF1516_EDU87177.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIHQQHPASRLFPFCTGKYRWHGSAEAYTGREVQDIPGVLAVFAERRKDSFGPYVRLMSVTLN
>SEQF1516_EDU87178.1 hypothetical protein ECH7EC4501_3587 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHRKKLLFNAMIKGVKKNNNLHETHPDGSIVNSPITGIPPAFYGCFH
>SEQF1516_EDU87179.1 transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATYGGQFTLTDNAMAESINGLYKAEVIHRKSWKNRAEVELATLTWVDWYNNRRLLERLGHTPPAEAEKAYYASIGNDDL
AA
>SEQF1516_EDU87180.1 iron permease FTR1 family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFVPFLIMLREGLEAALIVSLIASYLKRTQRGRWIGVMWIGVLLAAALCLGLGIFINETTGEFPQKEQELFEGIVAVIAV
VILTWMVFWMRKVSRNVKVQLEQAVDSALQRGNHHGWALVMMVFFAVAREGLESVFFLLAAFQQDVGIWPPLGAMLGLAT
AVVLGFLLYWGGIRLNLGAFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFDMSAVLSTHSLFGTLMEGIFGYQ
EAPSVSEVAVWFIYLIPALVAFALPPRAGATASRSA
>SEQF1516_EDU87181.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMAFYGKWFACLWLATSCVQAASTDNKALEIIRRADEIRSPNKPFRYTLTVTEYKAGATQPENKQVLDISMRFMKPQGN
EKADARSLVRFIYPPRDKGKIMLSDWYDLWFYTPELRRPMPISRQQRLIGQISNGDVIVTNFEYAYDSTLMGEVTCAEKQ
CYKLALVRKSADITWPKVIYYVEKDGDNRPWKAAYYSQDDQLIKEVLYQDFQPVLGKTRPMKITVTDVRHGNNYSVMEYS
DVRLESLPEFHFTKEYIQRGAK
>SEQF1516_EDU87182.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCLLAPENPYPIYALPPLVRNAIIETQKNTQAPLAMVATSALTAISIACQNQIDVCRPGNLHGPVNLYSLILADSGERKT
TVDKVFMKAFYLRDEALADEYAKLVENYSTEKEIWEQKQKALESKFHKEIRAGKDYKATESELETHLNKPPVPPQIRRTI
FNETTIEGMLKYYSDSNRSFALVSSEGGVIFDSRAMSKLGIINTLWDGGSLFIDRKSSPGINLKEPRLTISVMIQPDVYH
KGFCTRKKEIVKTSGHHARFLMCQPTSTQGTRIMINELIDESLAMSGERRCLHFSPQAARIWTDYYNDVESKLGGLGPLR
HCREYAAKNAEYMARLAGLIYHSSGEEGEISPYTAEMARELAIWYGNEYVRLSNPLTFDNSALTVPVRLIPEELELFNWI
KSYCIEKGILCMKKNDILQRGPNRFRKKDKINWLLDLLYEQNRVVPVIEGKTLCVAPNFDL
>SEQF1516_EDU87183.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGFAQGLLAGFSTVDQAMTRRKELGLREAQLARQQKNNERDFEFAQSQFEHNKNVDQRNFDYRAKVDDRNYALKEREFN
ANQNYRNASLGMEQQRLQLQKYNQRRLEY
>SEQF1516_EDU87184.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRPSWRLLPMNKPVVLSDLDDTLFQTRRKMVDELALEPFRTGAVDRTLNPRSFMTEEQSMLVDWLLEQAELIPVTARGTE
EISRVRIPFHSWAITTHGAVILTPEGKPDEEWKAHMLGQLAPYQEKLTSMQRLITEMMDAKGINAWARLNFEYGEMAVYM
VMKHRDSTRLDELNAIADEIETVFPTEGFYIHRNSNNVAWLPTPVEKGLAVSWLLEKLRAERGVFPVIGLGDSLSDHRFM
KLCSWFGIPRQSQFADAISQRIFGEN
>SEQF1516_EDU87185.1 hypothetical protein ECH7EC4501_3602 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIFLFTPVYKDYYAPSANCASWIPWFHAVNTEGFEKCIYCLLALLLLTAFIPFFHEQQ
>SEQF1516_EDU87186.1 IS66 family transposase orfC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRKYLIRITELERLLSEQAEALRQKDQQLSLVEETEAFLRSALARAEEKIEEEEREIEHLRAQIEKLRRMLFGTRSEKL
QREVEQAEAQLKQREQESDRYSGREDDPQVPRQLRQSRHRRPLPAHLPREIHRLEPEESCCPECGSELDYLGEVSAEQLE
LVSSALKVIRTVRVKKACTKCDCIVEAPAPSRPIERGIAGSGLLARVLTGKYCEHLPLYRQSEIFARQGIELSRALLSNW
VDACCQLMTLLNDTLYRYVMNTRKVHTDDTPVKVLAPGRKKAKTGRIWTYVRDDRNAGSSEPPAVWFAYSPDRQGKHPVQ
HLRPFRGILQADAFSGYDRLFSAEREGGALTEVACWAHARRKIHDVYISSKSATAEEALKRISELYAIEDEIRGLPESER
LAVRQQRSKVLLTSLHEWMVEKNGTLSKKSRLGEACSYVLNQWDALCYYSDDGLAEADNNAAERALRAVCLGKKNFMFFG
SDHGGERGALLYGLIGTCRLNGIDPEAYLRHILSVLPEWPSNRVDELLPWNVVLTNK
>SEQF1516_EDU87187.1 ISSfl3 OrfC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDGYSVYKSLADNDPGITSACCWSHARRGFANLYKASREPRAAMALRKIAGLYRIEKFIRERPVEKIRQWRQRYSRPIV
NDLFAWPEEQEPCCPPDGPLNKAINYILNRRDELSCFLSDGAVPLDNNICERAIRPVVMGRKAWLFAGSLMAGNRAAQIM
SLLETAKRNGLEPHAWLTDVLTRLPEWPEDRLEELLPLEGFTFSG
>SEQF1516_EDU87188.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVSLRKMKNRNIFFSLSEQTFISRYIKLNKLITLIKSTDKDQQVRQVTLTRYEWDIYYLYFKIDNKRILHTLLKKDVKY
ISHYKISVFNKFEIACDSDGFYIFKALIQLRRFTGFKNVRLYQLH
>SEQF1516_EDU87189.1 curli production assembly/transport subunit CsgG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQRLFLLVAVMLLSGCLTAPPKEAARPTLMPRAQSYKDLTHLPAPTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSAT
AMLVTALKDSRWFIPLERQGLQNLLNERKIIRAAQENGTVAINNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFG
IGADTQYQLDQIAVNLRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGEVGYTSNEPVMLCLMSAIETGVI
FLINDGIDRGLWDLQNKAERQNDILVKYRHMSVPPES
>SEQF1516_EDU87190.1 hypothetical protein ECH7EC4501_3582 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMTDMKKAVCFQQDLHQASVHDRRMRRERLIRLPNPHRL
>SEQF1516_EDU87191.1 hypothetical protein ECH7EC4501_3467 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTFFISHDADSRMANTRLAEQQQTSYLCSFMLFPQPA
>SEQF1516_EDU87192.1 AntB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSQLIPVFNGTIANETTLLVNARDLHTFLGVGKRFASWITERIEEYGFVENQDYIAISQKREIGYGRGKKDYHLTLDTA
KETAMVERNEKGRQIRRYFIECEKKLRNMQSAQAEPQQQFTDEEIILLCYMQLWMEKAQDLSKHLYPIMKELNSSYTNKL
YDIAFETIYMVTKNRDVLLREAARLDQSSFVVQRARPMLKSLRARQFEF
>SEQF1516_EDU87193.1 bifunctional protein PutA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQLENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLD
FAEQILPQSVSRAAITAAYRRPETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGKLVSTHNEASLSRSLNRIIGKSG
EPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLEEKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGI
YEGPGISIKLSALHPRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPELAGWNGIG
FVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGLEGYPVYTRKVYTDVSYLACAKKLLAVPNLI
YPQFATHNAHTLAAIYQLAGQNYYPGQYEFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLEN
GANTSFVNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDLANEHRLASLSSALLNS
ALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPREVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQ
MQQLIGILVREAGKTFSNAIAEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNSVL
AKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGSTEVATLLQRNIASRLDAQGRPIPL
IAETGGMNAMIVDSSALTEQVVIDVLASAFDSAGQRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVI
DSEAKANIERHIQTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYNRNQLPELIEQ
INASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPFGGEGLSGTGPKAGGPLYLYRLLANRPESALAV
TLARQDAEYPVDAQLKAALTQPLNALREWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDE
QDALTQLAAVLAVGSQVLWPDDALHRQLVKALPSTVSERIQLAKAENITAQPFDAVIFHGDSDQLRALCEAVAARDGAIV
SVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
>SEQF1516_EDU87194.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARSDYDIINLSLEHELNEWLAERGYAGLVDNRNRLAEVVTRKLQDSFYINVSRDALNTAYSEHPEWFSGLVSGDEN
>SEQF1516_EDU87195.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDILEDMIYRRTLSCGTIQVTRDQGEVSLDDLFDIAERRNPKRAFLFVSKVLGRHIPVPPSVMRQAYRQLASQFPSTLT
GPVLFIGMAETAVGLGAGVFDEVRHQHRESVYLTSTRHPVDGTLLCEFKEEHSHATDHLIYLPDDEEKRRRVTNARTLVL
IDDEATTGNTFINLLSALRNTGKLQHIEQVIAVTLTDWSGNALSERTPLPVTSVSLVSGQWGWTPLPDAPVPDMPKVNVT
SRGEWDIQGKQSWGRLGMLAPAADLGHEVSVHKGERILVLGTGEFVWEPFLLAERLEAAGAQAFYGSTTRSPVAVGYAIE
SAISFTDNYGLGIPNFVYNVAHQQFDRILVCTETPAESIDTQLLKALAEVAPVVEIVTYE
>SEQF1516_EDU87196.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFSVIFFWVITGLITILFLKSIITDLIKNLNKTDIALYILAFLSAGYTFQYIYNDNIFSELWGVGLFVTLIVLNIVFNL
FFRLLFILSKMILMSRHIRKMQKKLKQTSVPDFIYYSIEKHNKYPIYVLHMPSNNIIEIGYNIINTDLVIGEKIHFRTLS
NRSLYFNLTHPPLIATIKDDVFCTLHDYYNHNNETKSTIDNYISKIKDNHNTPWLLNNENVQE
>SEQF1516_EDU87197.1 IS1203 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLLDKLHEQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLKREIQRVYDENHQVYGVRKVWRQLLREGIR
VARCTVARLMAVMGLAGVLRGKKVRTTVSRKAVSAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGCIV
GWRVSSSMETTFVLDALEQALWARRPSGTVHHSDKGSQYISLAYTERLKEAKLLASTGSTGDSYDNAMAESINGLYKAEV
IHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHIPPAEAEKAYYASIRNDDLAA
>SEQF1516_EDU87198.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQDNQMARYGVNRPDNPDSNTLGLRNALAIAGAKNGIREAEQDRQMNILTGASAPARQKLSVGGQLVAA
>SEQF1516_EDU87199.1 putative isochorismatase family protein, rutB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYV
EAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFT
SIATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFVQKAALFNIETFFGWVSDVETFCDALSPTSFARIA
>SEQF1516_EDU87200.1 transposase subfamily [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQWVTAARKGLGTPGSRTVAELESEILQLRKALNEARLE
RDILKKAAVDSICQCNTPFNYLFHCPRRYRLSV
>SEQF1516_EDU87201.1 tellurite resistance [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVSLVKGGNVSLTKEAPTMNVAMVGLGWDARVTDGQGFDLDASVFAVGEDGKVLSDAHFIFFNNKTSPDGAVEHQGDNR
TGEGDGDDEQVKIDLTKVSADIKKLVFAVTIYDAEARKQNFGMVSNSFMRVYNNDNGTEIARFDLSEDASTETAMVFGEL
YRHGTEWKFKAVGQGFAGGLSALASQHGVNV
>SEQF1516_EDU87202.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIAHSQPLMEALGKAIEAGDQEAATRLFGQLPKGHPLILMSNEGYAAKAGQAVINLQKIFGDKPDMAIDSLNTPENLDVL
SGVFAPELQQRIGMPDSTGDKTIKEARIGSIVPAQQEGYVLIGLDLTYSDGSTAHKPVTEYGSAHPDDQTVLAIPVDKAI
AQVRDRSKFAEISKNYGYFMPKQQGLSLKELQKGASNVAADAIKNGGNAQAAVDEYYAATGSQPHQQKIQQQKLQQQVIN
WAGDDPDKLSFARNVAARQPEMLEPQNQKLLENGYANFLRIQKARGEQARDESASSASQFIRGLKQNYAQ
>SEQF1516_EDU87203.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARTPDENQAGRGGRFTTTGEVKGQSFQKGQAPAPENAAGRQGETLEGDMVRRGLPSPDAQNATAPVREGLPAPDIARNV
RMPQPESLPRTVRDSLPELAQQAEVRRQAGGNRDIPQPETIAPESETTVSTDREATVRGGEVRGKKIEDFGEEIKGAAKH
RYAQLAETLGKTLEDRDYATQPLSKLFPKPDYAKLANEGADADTLAMIALYRSDIPAKTKHNTAGWGESIKKVRHSVSEM
LNGTVSAKRLAEWMEGRMPSRYADTWQLLRTLPPSQMDRASAYRVVSGVYQAAGGKRYDPPQKLYSLRNKDNKGSNLFFS
ESRDELLAKAKVWFAEQEEKSQAKGDEKTAPSPDDKIRFDVYRNTRSGDIFIAYGKNKMRVRGGFKSASDARKYIDSHRD
ELVRHVKEMREISREEQRNATNRDRTGPERRKGNVSPEQFSDAFGFRGVQFGNYVEGPRRQADLNRAYDSLHDLAEVLNV
PTKALSLNGRLGLAFGARGKGKAAAHYESGEVAINLTKGNGPGALAHEWFHSLDNYFGRYDVSNDGKITSGGDFMTEAQR
VRRIFKDGRYVDAEYPVRQEVYDAFKGVIQAIKNSDMPRRSALLDEVRSKPYWSTDVEMAARAFERYVQDKARMAGVEND
YLVNIRKAPEHNTDNTYAYPTNAELDGGIREAFDHLFRTLKTRETDKGVAFYSRKGVTRTPEGNLISDVNRSAEAKGSPV
PQVEAVARGVMSGIKDSDLKVRVVKSQKEAEALAGELFDGYGRVHAFYRPDKREIVLVADNIPDGRTVREKLRHEIIHHA
MEHVVTPAEYQTIIKTVLKTRDSDNVTIREAWRKVDASYGKESPEVQAGEFLAHMAEKQPNKFVAAWERVVALVKGVLRR
TGLLKPTELNDIRLVRETIRTLGQRVREGYTPREDGAGASFQYSRSGKRDPFKVPEGEGERYRDDLARMMKSLRTTDLTV
NIGRTPPVLRHLGAPDLPLVISRDTVRKATNGVKHVVPMDVIERLPELMHDPDAIYRSATERNAVVMLLDAVDKNGDPVV
SAVHMKAVRSRLEINKVASVYGTENGKKLKSMEMTGLTLYRREKLSRDNLLHRGLQLPKGEHSYRGSADKILYPEDIRKG
PYYSRTSSLTPEETIASRFVRQMQDKFQVLKAVQENIRKTGGKVDDSNNAYMAEELFHGKAENDLNVMKERYVQPLAKLL
ADYKIAQADLDEYLYARHAPERNAHIAKINPKMPDGGSGMTNAEAAEIMQRVRNSGKQAQYDRLAGIIDDMLARRRELIR
EAGLEENGVVDAWQNAYRYYVPLKGQDVDGVVSLPRTGKGFTIGGRESRQAMGRASRAQSPSTQAIQDLSESLIRHRKNE
VGNAFLKLVQDNPDKDYWQVFTDDRPDTMRTIAERKDQETGETIREVVERPVPMAMMADRYFTTKKNGKTYYIKLHDPRL
MRAMKSMGPETSNAFVRTLGKVNRFLATVNTSYNPEFLVSNFIRDVQTAVMNLKAEQGRSDGKLKGLDNLSALAVVKDSR
SAMSAVYASLRGKTLTGKGAQWQKVWKEFVEDGGKTGWFNMGDLEGQQKEMDRLVSLAKGGWKGQSIGAWNSFLNLVEDA
NGAVENALRLSAYKHARDAGLSRQQAASLAKNMTVNFNRRGEHGALMNSLYMFANASIQGTANLVRTLGHLNGEGPLLER
LRWKNLNVPQKIALAAVGAGYLLGSLNRSVAGEDDDGVNWYDKVPSHVKERNLVIMKSVFGGKAGEYWSIPLPYGYNVFF
LLGHTAEGVAAGDLTASRAAGNVVGGVLGAFSPIGSETSETLSGALLKNAAPTILRPFANLAMNENFMGAQIYQENMPFG
TPKPDSQLGRRSTPEAYKAFASWLNAFSGGSQYRPGAVDITPESLKFWIDYISGGTGRFISKTTDAAVKSLNGIDIPEQQ
VPFLGKISGEVMPYADQQKMYDRMTEIAQYHAELKSLTGAERTAFIDENNGKLSMNGLMQDTRKRLKDLRKQRDAIYADS
TLSLAQQSAMVKSVERDMKIAVDRFNREYNKKVGVD
>SEQF1516_EDU87204.1 efflux ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGEILAVNCVLLLILFFVFYQLLFYSRDVKFAFLNLFRHKRRSFSTITAIVLGGVAIFLYGGFIDYSFWILKEQTIRTN
IGHVQIYNQHYFETSNKNKSLIADYAALKKAILSDPTLAADISTLSGQLEFTGVISHYESETSSYFSALGVEPLPALKLG
SFDKIIAGSDLSRVKGDEITLGSGLAKTLNAKYDDWLDVMVVNTAGGQGALSLKMRGIFESGIKDYDDVAMKIPLDTAQR
MMGTDGVSKVLILLKEDDTAAFSAKLRQFIERNHLPLVVKDWRDVSLFYQQVEGLLSGIYFFIKLIVALIVIFMIGNSMA
MNIVERTREITTLRAIGLKPLHVTRLFLTEGIFIGVIGAVGSLLVGGVLAWIINLYGIAMPPSPGQTIGYTAFIKTSNPE
LIWVTVVLPILTATGASVLPALRASRLNISDAFKFS
>SEQF1516_EDU87205.1 putative dead/deah box helicase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVHKSDSDELAALRAENARLVSLLEAHGIEWRRKPQTPVQRVSVLSTDEKVALFRRLFRGRDDVWALRWESKTSGKSGYS
PACANEWQARICGKPRIKCGDCAHRQLIPVSDLVIYHHLAGTHTVGMYPLLEDDSCYFLAVDFDEAEWQKDASAFMRSCD
ELGVPAALEISRSRQGAHVWIFFASRVSAREARRLGTAIISYTCSRTRQLRLGSYDRLFPNQDTMPKGGFGNLIALPLQK
RPRELGGSVFVDMNLQPYPDQWAFLVSVTPMNVQDIEPTILRATGSIHPLDVNFINEEDLGTPWEEKKSSGNRLNISIAE
PLKITLANQIYFEKAQLPQVLINRLIRLAAFPNPEFYKAQAMRMSVWNKPRVIGCAENYPQHIALPRGCLDSVLSFLRDN
NIAAELIDKRFAGTECNAVFMGNLRAEQEEAVSALLRYDTGVLCAPTAFGKTVTAAAVIAKRKVNTLILVHRTELLKQWQ
ERLAVFLQAGDSIGIIGGGKHKPCGNIDIAVVQSISRQGEVEPLVRNYGQIIVDECHHIGAVSFSAILKETNARYLLGLT
ATPIRRDGLHPIIFMYCGAIRHTAVRPKESPHNLEVLIRSRFTSGHLPSDARIQDIFREIALDHDRTVAIAEEAMKAFGQ
GRKVLVLTERTDHLDEIASVMNSLKLSPFILHGRLSKKKRAMLISGLNALPPDSPRILLSTGRLIGEGFDHPPLDTLILA
MPVSWKGTLQQYAGRLHREHTGKSDVRIIDFVDTAYPVLLRMWDKRQRGYKAMGYRIIADGDESVI
>SEQF1516_EDU87206.1 D-isomer specific 2-hydroxyacid dehydrogenase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALAWHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEM
LKPSVPLFRLEDTGMGEQMQEYAVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRF
PLRCWSRTRKSWPGVQSFAGWEELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPDGAYLLNLARGVHVVEDDLLAAL
DSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHVAAITRPAEAVEYISRTIAQLEKGERVCGQVDRARGY
>SEQF1516_EDU87207.1 tellurium resistance protein TerC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSTHIGFPTETVIVFIALSVGAIFIDLFMHRDDKPISLKSAALWSVFWVVVAMAFAGFLYIHHGAEVASLFVTGYALEK
VLSVDNLFVMMAIFSWFAVPDRYRHRVLYWGIIGAIVFRGIFVAIGTSLLSLGPYVEVVFAIIVAWTAVMMLKSGDDDDE
IEDYSQHLAYRMVKRFFPIWPKLRGHAFLLNQKEVDAELAKPENSDVTIGRGKKAALYATPLFLCVAVVELSDVMFAFDS
VPAIIAVSREPLIVYSAMMFAILGLRTLYFVLEALKQYLVHLEKAVIVLLFFIAAKLGLNVTDHIWHHGYSIAATTSLYV
VLGVLALGILASVMFPGKPESEEKGS
>SEQF1516_EDU87208.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRTLKISSLLCVALPLTVQADCLSGDEVAQNSDVTLYEQVSYVNKQASAWQIAGKNPYTRHNGYQEAGIGINSGCSIID
NTLDLKLNLYGINEYALKPAGKFETDDSRTRALINRLSLVYSASDSVQFEAGKFAAPSGMFFLRSPSDLQTHYYTGFQST
RLHDPKMTSAYQASSWGAKMSVDTRDYAFSASVIPKLATIDKRYVTSGNWSANQQGNSDEAYLLSFSDHRFGEHTPTVNV
RLGPSPSLALSDSYHYTPQLTLNVDAAYHRSQQWRHLSHRETAQVEEYQFPDSLYETKDESGVELALGGQYTSDNFSVFG
VEYYFQSEGYSRAEQRQQRELIDFLNTTTGYAPLDQAFDSYKYLMASEISNTANQGMLQGKHYLNAWASLPLAGESTLQP
SLVVNLVDGSTLLGLHYSTPLSAISNQLEAYAGGYSALGSRYSEFALFGDTLGLYLGFKYYL
>SEQF1516_EDU87209.1 putative acyl-carrier protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTMNDAIEQRKEVLMTIKTEIIQRLNIQRDEAQIDDDTALFGNGFKLDSVDATEIVVLLDKVFDIKISESDDPSYMRSI
NSLATFVIQKKND
>SEQF1516_EDU87210.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRGMNILLSIAITTGILSGIWGWVAVSLGLLSWAGFLGCTAYFACPQGGLKGLAISAATLLSGVVWAMVIIYGSALAPHL
EILSYVITGIVAFLMCIQAKQLLLSFVPGTFIGACATFAGQGDWKLVLPSLALGLIFGYAMKNSGLWLAARSAKTALREQ
EIKNKA
>SEQF1516_EDU87211.1 biofilm PGA synthesis N-glycosyltransferase PgaC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMRFVFFWPFFMSIMWIVGGVYFWVYRERRWPWGENAPAPQLKDNPSISIIIPCFNEEKNVEETIHAALAQRYENIEVIA
VNDGSTDKTRAILDRMAAQIPHLRVIHLAQNQGKAIALKTGAAAAKSEYLVCIDGDALLDRDAAAYIVEPMLYNPRVGAV
TGNPRIRTRSTLVGKIQVGEYSSIIGLIKRTQRIYGNVFTVSGVIAAFRRSALAEVGYWSDDMITEDIDISWKLQLNQWT
IFYEPRALCWILMPETLKGLWKQRLRWAQGGAEVFLKNMTRLWRKENFRMWPLFFEYSLTTIWAFTCLVGFIIYAVQLAG
VPLNIELTHIAATHTAGILLCTLCLLQFIVSLMIENRYEHNLTSSLFWIIWFPVIFWMLSLATTLVSFTRVMLMPKKQRA
RWVSPDRGILRG
>SEQF1516_EDU87212.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLIVVSIMVTLLSGCGSIISRTIPGQGHGNQYYPGVQWDVRDSAWRYVTILDLPFSLVFDTLLLPIDIHHGPYE
>SEQF1516_EDU87213.1 putative outer membrane transporter of ShlA/HecA/FhaA exoprotein family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLRFNFGLLLILCCFQVAAKDSLDNLIKQQKNADESTLRAHKLEKKDVYSNAQRNAFTLGDLPQEKNCFIINRIELEDN
FLGGQLISEVQKAIAGRCVGSAGVQKIAAALQDYYINAGYITTRISIPSQDISKGKLRFQVNAGKIEKTIVEGNDISEWM
LPFQRNDILNIRDIEQGLENLQRVPDVDVKINIEPGTRDGYSIVHIDTHRGKNWSVRASYNNWGDEETGRYQTTSVGYLF
NPAKMGDLFYLAGTRSTTGQYENVSSYYSIPVGYWEYGFFYSKSKSQQVIPLSYISLDYVGISEYLSAKATHTVYRDKTK
KFAGSAELIRRKSNYTLNGEELTLQARDMGNIKLGLNYKQQLPGAFWDSTLSWQRFLTWFGGEKTPDMQYGDVSPVSNIF
NFEGNYTRQIENGYYNTAFFAQYAPRELTLQDKITVGDRWSIRGFENSVGLSGNDGFYIKNTLAFPLPGMKANYYAGLDF
GQVYQDASYGDESLVGSAVGIDGNIKSLEYNFSVSTPLKYPATLDIDRVNVNFNFSYQM
>SEQF1516_EDU87214.1 ATP-grasp domain family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKKIWFMEGLSSQRDIIQGVKSFAQKNNFAITVFASHRNERNEILSVADYSLTEPEDPQKRLQFIQETIQTYGIHHIHT
GRNSQWFEEHRSAIEPTGATLTTGATGVDWLTLADEKVTFAQFMEQKGLPVVPSWRVNTLAELKTHLAAPPFTDSPVCVK
PVTGIYGMGFWRFDDSASPMAVFNHPEHRLVSPQQYIAAASAAESFKPLVLMPYLPGPEFSVDILADKGEILAAVGRRKE
GAIQYLVNEGSAWELACDCARVMKADGLVNVQTRNDVNGNPVLLETNMRPSGGVGYTLHSGVNLPGLFAAFKLGLMSEDM
VRQSAKNTFSPVAVRSITDVIAYPESLSNLLN
>SEQF1516_EDU87215.1 antirestriction protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTVSHNSTTPSVSVTTASGNNPPQLVATPVPDEQRISFWPQHFGLIPQWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNN
GGAFMAPEPDDDDDETWVLFNAMNGNRAEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRII
D
>SEQF1516_EDU87216.1 ribosomal protein L31 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPNIHPEYRTVVFHDTSIDEYFRIGSTIKTDRVIELDGVTYPYVTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRF
VDAKKGG
>SEQF1516_EDU87217.1 LdaB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVAQKLEAAGCWRRASDRWLFVMGNVECTEAQREWLLLRRNYCLAQISSPPLPETLDISEVAKAADATLRRMGIATPSGE
VFRKGTPVC
>SEQF1516_EDU87218.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTINFRRNALQLSVAALFSSAFMANAADVPQVKVTVTDKQCEPMTITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERE
NIAPGFSQKMTANLQPGEYDMTCGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDA
IKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHRLEKALFGDNTTKGMDQYADQLY
TDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKISGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKV
DANFKKVDTILAKYRTKDGFETYDKLTDADRNALKGPITALAEDLAQLRGVLGLD
>SEQF1516_EDU87219.1 curli production assembly/transport subunit CsgE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRYLRWIVAAEFLFAAGNLHAVEVEVPGLLTDHTVSSIGHDFYRAFSDKWESDYTGNLTINERPSARWGSWITITVNQD
VIFQTFLFPLKRDFEKTVVFALIQTEEALNRRQINQALLSTGDLAHDEF
>SEQF1516_EDU87220.1 gram-negative pili assembly chaperone [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIFAYLLVLVFSMSMSSSAFASVVMTGTRIIFPGDAKEKTIQLRNTSDQPYIINIHVEDERGSDKNVPFMPTPQTFRME
AAAGQALRLLYTGNNLPQDRESVFWFSFSQLPYLNKNDKSQNQLILALTNRVKIFYRPSSIVGKSSDAPKNLTYQVKQNR
IEVTNPTGYYVTIRAAELLNNGKKVPLANSVMIAPQSTTEWTLPSGISVAPGAQIHLVTVNDYGVNVTSEHAL
>SEQF1516_EDU87221.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSPFIQQIADNRVCQVLTCLPEKFVVDFANGIDVAQEHIRTAGERTFFRRLKEGLTGEGAARQNAINASLAQGVEASLR
WLTEMTTSLATTNYAITRVNDRVSSLVSDTARLAHYSADTREQLLTLADQVHHKLNHLEEKLHRVDQVQRAQLHLEQIFS
WWSAGRYASFSPAGRCYVALEELRWGAFGDVIRQGETGQVNQLLDILRHKALTQMAQESGGSATVRLNTLDWLGGQGREQ
ADNEWHDAINWLGDWCSEEQHPVIWSTTQAAEHLPVRMPRLCSAERLSESMVDEIFQKGAA
>SEQF1516_EDU87222.1 biofilm PGA synthesis lipoprotein pgaB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRNGNKYLLMLVSIIMLTACISQSRTSFIPPQDRKSLLAEQPWPHNGFVAISWHNVEDEAADQRFMSVRTSALREQFAW
LRENGYQPVSIAQIREAHRGGKPLPEKAVVLTFDDGYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDELVD
REYFATWQQVREVARSRLVELASHTWNSHYGIQANATGSLLPVYVNRAYFTDHARYETAAEYRERIRLDAVKMTEYLRTK
VEVNPHVFIWPYGEANGIAIEELKKLGYDMFFTLESGLANASQLDSIPRVLIANNPSLKEFAQQIITVQEKSPQRIMHID
LDYVYDENLQQMDRNIDVLIQRVKDMQISTVYLQAFADPDGDGLVKEVWFPNRLLPMKADIFSRVAWQLRTRSGVNIYAW
MPVLSWDLDPTLTRVKYLPTGEKKAQIHPEQYHRLSPFDDRVRAQVGMLYEDLAGHAAFDGILFHDDALLSDYEDASAPA
ITAYQQAGFSGSLSEIRQNPEQFKQWARFKSRALTDFTLELSARVKAIRGPHIKTARNIFALPVIQPESEAWFAQNYADF
LKSYDWTAIMAMPYLEGVAEKSADQWLIQLTNQIKNIPQAKDKSILELQAQNWQKNGQHQAISSQQLAHWMSLLQLNGVK
NYGYYPDNFLHNQPEIDLIRPEFSTAWYPKND
>SEQF1516_EDU87223.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGEMNEVYCLRSPSLANHVLSCIPASPVQLTFSIADNPPEICSLVVFVSSPKIK
>SEQF1516_EDU87224.1 minor curlin protein CsgB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYDQVQGDNMKNKLLFMMLTILGAPGIAAAAGYDLANSEYNFAVNELSKSSFNQAAIIGQAGTNNSAQLRQGGSKLLAVV
AQEGSSNRAKIDQTGDYNLAYIDQAGSANDASISQGAYGNTAMIIQKGSGNKANITQYGTQKTAIVVQRQSQMAIRVTQR
>SEQF1516_EDU87225.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQGMANSISMTWQLLCDEHGFTREHYNQLKKFSPETLREIIAEIASCHPSTSVLLRNKWLTPPEDILEQITREYERRIQ
NCPPFRSEKEAESWLNELSFAVIAPLYRVAPEQTEQVESFVLQLIAEQERVWELILTNDGYSWHCALYDILFHLVLRNME
DQPEHQKQRITKIFYEPDARLVAEEIKFRIQSLYDDEQKRALSELVNDFTSKE
>SEQF1516_EDU87226.1 hypothetical protein ECH7EC4501_3511 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIFPSDYRGASGQPDYCVFPADWHKNAFKICVLRYFLTFRMRFL
>SEQF1516_EDU87227.1 protein phoH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTSCTGHVLDNQRATTRGVFSSGSHLVTLHFQPHPFFSCVTDAVNGARSRFSAFYPKANYGLQGSQPSDVRAHNRAANG
ACDEYKQLKVLSMGRQKAVIKARREAKRVLRRDSRSHKQREEESVTSLVQMGGVEAIGMARDSRDTSPILARNEAQLHYL
KAIESKQLIFATGEAGCGKTWISAAKAAEALIHKDVDRIIVTRPVLQADEDLGFLPGDIAEKFAPYFRPVYDVLVRRLGA
SFMQYCLRPEIGKVEIAPFAYMRGRTFENAVVILDEAQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLPRGVCSGLSDA
LERFEEDEMVGIVRFGKEDCVRSALCQRTLHAYS
>SEQF1516_EDU87228.1 hypothetical protein ECH7EC4501_3543 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGLIWHFIPHSVVNCRYSLYSPGKFVCVKKWVEKKDNK
>SEQF1516_EDU87229.1 holo-(acyl-carrier-protein) synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIGTDIVEIARITKAIINGEMAFYERVYTSHERLLINPAEPDYERASGFWAAKEALVKAIGCGFRDGVRFQDIEIKHDA
AKAPYFVISGRLQEIFIGQGLQNNSLSISHCRTHAIATVIVY
>SEQF1516_EDU87230.1 urease accessory protein UreG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIIKQPLRVGVGGPVGSGKTALLEALCKSMRDTWQLAVVTNDIYTREDQRILTEAGALEAERIVGVETGGCPHTAIRED
ASMNLAAVEALSEKFGNLELIFVESGGDNLSATFSPELADLTIYVIDVAEGEKIPRKGGPGITKSDFLVINKTDLAPYVG
ASLEVMERDTLRMRGERPWGFTNLKSGEGLQNIIAFIEEQGMLGK
>SEQF1516_EDU87231.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDKILWYMQRVVRNSRNPEFMNEVKDACLKKQAFCFEAPDGFLVLRSVLSADGIPYVLVLLGVCTGSNSVERYLPEVKT
LTHLAGGRWAEFHTARRGFIRLGKRLGFERMPDDEDGFMVFRIAV
>SEQF1516_EDU87232.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNENKIKRLEQLLQARQREFATKWGRAALPHERLTYFPLEDLIKNNGKKIRSDKKHFLECNEDK
>SEQF1516_EDU87233.1 urease accessory protein UreE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYLTRRVETPAQTTASVTLPVDMRVKSRIKVTLNDGRQAGLLLPRGLLLRDGDILSNENGDEFIKVIAADEAVSVVRCA
DPFMLAKACWHLGNRHVPLQIMPGELRYHHDHVLDDMLRQFGLDVDFAHLPFEPEAGAYASKSHAHNHDQEHSH
>SEQF1516_EDU87234.1 putative fatty acyl chain dehydrase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKYTIPSKIFLEMGGWRQPLLMVDKIADYKYGENGFVSVVKHVTYNEPYLLGHFPEDPIMPGVIISEIFGQASEYLSFL
TDICDIWRERFEEELKSLRDIHARIHRPEMLEIIRTWRSQVRGVLAAQNLKFKDIAYPGDSIDVVSKLAFSDASGFKHYS
VTAYVGKKLISQGTIINFRETK
>SEQF1516_EDU87235.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYNCGESYSEYDISLSDDENYDDDYYRERPCPGEVFGYDNTEDNDEAASDYALKINENSD
>SEQF1516_EDU87236.1 serine proteAse eata [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVGLNAEIRDNIRFGLEFEKSASGKYNVDNAVNANFRYSF
>SEQF1516_EDU87237.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRGANIWFASRRIVGVSALLTSASHPVGGLLLNNQPLREFRICHTP
>SEQF1516_EDU87238.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKPRWTLDQKKHHVAAWRASGLTREQYCELYDIPFKSLRQWPQDVAKAEKRARAPEIIPVSVSGSSGMTDGRPLSDEPV
TLFLPGGIRMCCQPSQLTDVFRALRHADA
>SEQF1516_EDU87239.1 putative phage portal protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNETNTMATKNDNGATPRFSQRQLQALCSDIDSQPKWRDAANKACAYYDGDQLPPEVLQVLKDRGQPMTIHNLIAPTVD
GVLGMEAKTRTDLVVMSDEPDDETEKLAEAINAEFADACRLGNMNKARSDAYAEQIKAGLSWVEVRRNSDPFGPEFKVST
VSRNEVFWDWLSREADLSDCRWLMRRRWMDTDEAKATFPGMAQVIDYAIDDWRGFVDTTVTEGQPSPLMSAWEEYQSWDR
QQNEWLQRERRRVLLQVVYYRTFERLPVIELSNGRVVAFDKNNLMQAVAVASGRVQVKVGRVSRIREAWFVGPHFIVDRP
CSAPQGMFPLVPFWGYRKDKTGEPYGLISRAIPAQDEVNFRRIKLTWLLQAKRVIMDEDATQLSDNDLMEQIERPDGIIK
LNPVRKNQKSVADVFRVEQDFQVASQQFQVMQESEKLIQDTMGVYSAFLGQDSGATSGVAISNLVEQGATTLAEINDNYQ
FACQQVGRLLLAYLLDDLKKRRNHAVVINRDDRQRRQTIVLNAEGDNGELTNDISRLNTHIALAPVQQTPAFKAQLAQRM
SEVIQGLPPQVQAVVLDLWVNLLDVPQKQEFVERIRAALGTPKSPDEMTPEEQEVAAQQQALQQQQAELQMREMAGRVAK
LEADAARAHAAAQRDNASAQREVALTQGQRYVDALNQAHTAEIITGVQNMEQEQDVLQQQMLYTLQQRMNEMSL
>SEQF1516_EDU87240.1 curli production protein CsgC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNALLLLAALSSQITFNTTQQGDMYTIIPEVTLTQSCLCRVQILSLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNIS
PDDRVKIVVTVSDGQSLHLSQQWPPSSEKS
>SEQF1516_EDU87241.1 putative monooxygenase rutA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDFALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSR
IQIYATAATLTLPPAIVARMAATIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKS
DFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFAPTAARMKQAAEQTGRDVGSYVL
FMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQKDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVAS
VPGAEGVLLTFDDFLSGIETFGERIQPLMQCRAHLPVLTQEVA
>SEQF1516_EDU87242.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTLSDTHVREVSRCPSPVTIWQTLLIRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
STCPRSQLINSIDILRARRATGLMTRDNYRTVNNITLGKYPEAK
>SEQF1516_EDU87243.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYGLSIMKPDGSVWISPGFTPQCLINKGTIPATEKSFFKTSIPSGKSCFFFIRTEKKADVMYTHEQIDGYHALRLHVIVR
GTNPGVTTVYAFANMVTPPSEYGIAMYNPDGEMIYHGEMMLLDAKLIPVDIKFEKDLGYPCAIMPALVGYYNWKRTPYDR
PIYTTSTGATGNKIYSCEHYSGGATWDIRKPYIDKVLVINTSVYD
>SEQF1516_EDU87244.1 glucans biosynthesis glucosyltransferase H [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPIAASEKAALPKTDIRAVHQALDAEHRTWAREDDSPQGSVKARLEQAWPDSLADGQLIKDDEGRDQLKAMPEAKRSSMF
PDPWRTNPVGRFWDRLRGRDVTPRYLARLTKEEQESEQKWRTVGTIRRYILLILTLAQTVVATWYMKTILPYQGWALINP
MDMVGQDLWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQLLIGRDKYSISASTVGDEPLNPEHRTALIMPI
CNEDVNRVFAGLRATWESVKATGNAKHFDVYILSDSYNPDICVAEQKAWMELIAEVGGEGQIFYRRRRRRVKRKSGNIDD
FCRRWGSQYSYMVVLDADSVMTGDCLCGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFATRVYGPLFTAGLHFWQLG
ESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDFVEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRW
CHGNLMNFRLFLVKGMHPVHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPELAIAL
FASTMVLLFLPKLLSILLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLFHTVFVVSAFLGWEVVWNSPQRDDDST
SWGEAFKRHGSQLLLGLVWAVGMAWLDLRFLFWLAPIVFSLILSPFVSVISSRATVGLRTKRWKLFLIPEEYSPPQVLVD
TDRFLEMNRQRSLDDGFMHAVFNPSFNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRRLVLLSDPVTMAR
LHFRVWNSPERYSSWVSYYEGIKLNPLALRKPDAASQ
>SEQF1516_EDU87245.1 protein YgiW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKVLIAALISGVSFGAFAQQGGFQGPEAERSTVAQAKELKDDAWVILEGSIVKKVGDERYEFRDNSGTIVTDIDDSIWA
GQNVSPKDKVRIEGEIDKDLSSVEVDVKALKLLK
>SEQF1516_EDU87246.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKIAVVYIGPKPVKKDTITGSRTLFPRLEPVHVDSAMAWQLLGFPDVWVRHEELDDVLKKQQQNEQLRQAQQAQERVL
AALAEAENSFVVSVNGQEVDLSKLTSARLATLCEAEELDIHKDPKETAEAFRIRVREAFRRRVAETEQHGGTE
>SEQF1516_EDU87247.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQMHKGFLLIGVFLYAAFVAPKIYAATPDAVNQVLQQGLPAQPAALATLTEALKKEYEARHNVVALVFYAYGLLRQADG
YAATNDFIHASEYAKSGFFWLDEAVDLQEKNQRVRYLRARVDAYLPADSGRCVVTVKDTEHMLADPAIWTTTIRDHILAM
RYRALRHCKDTTRANALLAQIKGQNAALAQSLTQDFNVVPEWDSEELTQVLLPLMKGE
>SEQF1516_EDU87248.1 hypothetical protein ECH7EC4501_3455 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQMVNNSNIILQEVFTVIELPPDKVYSLRNYSTETFPVSFEQ
>SEQF1516_EDU87249.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFEFTGEETPEQLEKMLEGLGDVDIDSHAQDVVTEDTTEKHADEEAQTQTGDNNVAPTPDASVEQTQDVKEPEAKGVLT
RDGKHVIPYEVLEAERSGKQRAEQEAALLRGQIAEEKRRVELLTSQIHQAGMKPTPLPENEKISDEQIARIREMYPEIGD
AVASLIRKNNYLQSRVQQSAQQAEGNGGEDLSPVLDAMNAVPVLKTWQESDPDRFSVAVSIDGKLQNDPAWKDKTLTERF
AEVARRTQVAFGEVSESSADNKADKTDIRKTAEEKVKTAEQEQAVPASPSDLGTTASVGTGDNFERLLGASHSEAEAIMR
GMTNAEIDALLEKLG
>SEQF1516_EDU87250.1 hypothetical protein ECH7EC4501_3527 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHENTVASPRKGEIIICMTRPVLSHEHSVSVSSFRINESVILLLYQQVIPITP
>SEQF1516_EDU87251.1 antigen 43 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAAVTSVPALAADKVVQAGETVNDGTLTNHDNQIVFGTA
NGMTISTGLELGPDSEENTGGQWIQNGGIAGNTTVTTNGRQVVLEGGTASDTVIRDGGGQSLNGLAVNTTLNNRGEQWVH
EGGVATGTIINRDGYQSVKSGGLATGTIINTGAEGGPDSDNSYTGQKVQGTAESTTINKNGRQIILFSGLARDTLIYAGG
DQSVHGRALNTTLNGGYQYVHRDGLALNTVINEGGWQVVKAGGAAGNTTINQNGELRVHAGGEATAVTQNTGGALVTSTA
ATVIGTNRLGNFTVENGKADGVVLESGGRLDVLESHSAQNTLVDDGGTLAVSAGGKATSVTITSGGALIADSGATVEGTN
ASGKFSIDGTSGQASGLLLENGGSFTVNAGGQAGNTTVGHRGTLTLAAGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAG
EIRFDNQTTPNAALSRAVAKSNSPVTFHKLTTTNLTGQGGTINMRVRLDGSNASDQLVINGGQATGKTWLAFTNVGNSNL
GVATTGQGIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYLRSENAYRAEVPLYTSMLTQAMDYDRILAGS
RSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDD
DGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQ
YTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDMTFGEGTSSRDTLRDSAKHSVSELPVNWWVQPSVIRTFSSR
GDMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARIRENITLGVQAGYAHSVSGSSAEGYNGQATLNMTF
>SEQF1516_EDU87252.1 hypothetical protein ECH7EC4501_3418 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFIKHDETPLFLLIAHLTAASKIEAPEVLTDVALLCVVINQP
>SEQF1516_EDU87253.1 urease, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPGEYKVKPGYIELNIGRATCSIIVENHGDRPIQVGSHYHFAEVNPALKFDRQKARGYRLNIAAGTAVRFEPGQKREVE
LVALSGARIVHGFRGDIMGELEANDE
>SEQF1516_EDU87254.1 hypothetical protein ECH7EC4501_3479 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLLVINPLLLLVKQCAVVPYATALMVLIRFIESENKL
>SEQF1516_EDU87255.1 putative rutD protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVCYDQRGTGNNPDTLAEDYSITQMAAELHQALVAAGIE
HYAVVGHALGALVGMQLALDHPASVTVLVCVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPR
LEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSSELHAALPDSQKMVMRYGGHACN
VTDPETFNALLLNGLASLLHHREAAL
>SEQF1516_EDU87256.1 PHP domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDMEDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVD
GEIDCSGKMFDSLDLIIAGFHEPVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNS
SFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPERILNVSPRRLLNFLESRGMAPIA
EFADL
>SEQF1516_EDU87257.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRKPWRAGKDLSTVVENMEIGTGQRGDGRHAFVTREELVGLKLARRRTSGGASYALNPGIEIDSTLMTVDFPTKPLNFK
ATGGFGSVLLEWDMPNYRGHSLTEIWRGTEDDLADAVLVATTPGQVYGDPVDPGWSGFYWIRFVNAAGVKGPWNAEKGTQ
AQTQIGVKAIIDQIRDEAAKSPVVSELRKEIKNAQGQAVKDAAIKTTEVVGTLREETTRTIGGIETRISTLDSSTSESLN
EVDKRITKLDKEGGEAFLAMWSKKAGVDGITAGIGIVAGKDSEGRPVSQVAISASQLFVFDPNNPDNTAYPFAVSGGKVV
IPKAMIYDAVIETLVSRKVVADEVKAGVSITSPVIRSAVIQNGNFQVDSQGNLNIGGLFSVTSQGQLTIRYSNQNVGLVI
RNDKIEVYDQNGRLAVRIGRLR
>SEQF1516_EDU87258.1 fimbrial usher protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKSVVSISAAMLVLLCQPVMGSEISPATPSDEDNYTFDPQLFRGSRFSQSSLAKLTTRESVAPGNYKMDIYTNNKLSGS
WNVTFKEAADGRVLPCLTPEVADAIGLKTGEDKGEKDPVCTFAKELAPGITSQTQLSQLRLDLSVPQSQLISRPRGYVPP
SELDTGASLAFMNYIANYYNVAYSGQNAHSQRSLWASFNGGINLGAWQYRQLSNMTWDNDKGNQWNNIRSYLQRPLPAIN
SQLMMGQLITSGRFFSGLSYHGVSLATDERMLPDSMRGYAPTIRGVAATNARVSVMQNGHEIYQTTVAPGPFEINDLYPT
SYSGDLDVTVTEANGAVSRFSVPFSAVPESMRPGTSRYNVEVGKTQDSGDDSMFGDLTWQHGMTNTLTFNSGSRIADGYQ
ALMLGGVYGSSLGAFGANLTWSHARVPESEAQSGWMSQLTWSKTFQPTSTTVSLAGYRYSTSGYRDLADVLGERHAASNK
QSWDSSQWRQQSRFDLTLSQSLANYGNLFVSGSTQNYRGGKSRDTQLQLGYSNSFSHGISMNLSVGRQRMGGYKDNSDDM
QTVTSLSFSFPLGGNGPRVPSLSNSWTHSTDGSSQLQSSLTGMLDEAQTTNYSLNVMRDQQYKQTTLSGNMQKRFSQTTV
GLNASKGQDYWQASGNVQGAMAVHGGGITFGPYLGETFALVEAKGAEGAKVYNSSQLEINDSGYALVPAVTPYRYNRISL
DPQGMDGDAELVDSERQVAPVAGAAVKVIFRTRPGKALLIKSRMADGSELPMGADVLDENNTVVGIAGQGGQIYLRTEQT
KGHLSVRWGEGANDSCQLPFDISGKDSNSPIIRLNETCQS
>SEQF1516_EDU87259.1 TerB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFFDKVKGAINSGRDELTRQVGRFKNKKFMQGTVAVCARIAVSSDGVSSEEKQKMMGFLRSSEELKVFDTNEVIEFFNK
LVSSFDFDVEIGKGETMKYILALKDQPEAAQLALRVGIAVAKSDGNFDQDEKLASREIAIALGFDPAEFGL
>SEQF1516_EDU87260.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYNANPNYEMDFMILKDVNEHMEGLFQRFSKLLPFRIDFAYRKDTPSFGHSCRHSMCIEMHRLLSETQTMLAGYYWVMEY
TSNKGLHIHFIGYLDGQRHNKSYRISRQLGDIWRRITEGEGYFHLCRAKDKYPVRIDHVIHYSDKSAVDDLRYALSYLAK
QDQKEHGIILRRSRLPEKSNRGRPRHN
>SEQF1516_EDU87261.1 transcriptional regulatory protein, C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIYIINDEVRFNSSSNKLTSLLTSEEVILTYPAGKCLKLLLDNAYSVVSHNQFFEKVWSDSSADVATNTLYQNISMIRRS
FREISSATIFNDVIRTVPRKGFKINEEISITVLDNNHNENESVESEENGTHTENINKNHIAKGIFTTKNTLLIVCFFAAW
GIVYISSYFFDMAFQSKSHTIKKIDAFSNYAQHPTQEGCSYFYDNKYFNSVDMLSPIIEKLQKMEINCKIHPYIYIATND
SMSGFYAFTCSQMLNSESPNNCNSLYYKAE
>SEQF1516_EDU87262.1 hypothetical protein ECH7EC4501_3417 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAEIFLITHPRVVFFFFCSYQSIKTHVNTLLSTQKIFCFLLNLRFPLAKNTRQSFFLPVADCCDMSCAQAVTNLVFLQ
>SEQF1516_EDU87263.1 hypothetical protein ECH7EC4501_3462 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLFFKLTNCIKSIQWNNFLHFSSNYGYKFCNVLFLRYLSE
>SEQF1516_EDU87264.1 hypothetical protein ECH7EC4501_3590 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNQRFRQDTVALVKHKLCYPVPVADITASFDIADNNFLETLDGY
>SEQF1516_EDU87265.1 hypothetical protein ECH7EC4501_3513 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFNIPDKNNHTKIHIHIILEKTSFLVLWYISFSSCLYNDMYSFSNTFCNYRFILSLLSKHHQKLEVTTAIMNIKRQIRMA
VNQ
>SEQF1516_EDU87266.1 malonyl CoA-acyl carrier protein transacylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMNNASQPTVLLFAGQGNPVIGMGSDLWDLNASTKHIWDCASDISGLNLRRLCQKGPMNRLIQTTVQQLAVTAINVTLYT
LCRERLENLTVVGSCGHSVGEYSALYAAGAISLETLFGMIHFRASLMHDESQRNKGAMLAVKGINREQLQTMITESGIAL
DISCDNTPRQQVIGGTQAALNEFATLLMAAGYEPVKLGVSGAWHTRLMEDGVQAMRDYLAGLDIASPEHQVLMNVTAKSE
VAPSIIKENLSLHLTHTVKWTESLDTFLNMPTSVAFLEISNKPYLGNMFNDFAGVDQQRVMHCRKAFSDAKVFK
>SEQF1516_EDU87267.1 IS66 family element, transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQLDKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTL
TGRVYDPAVQRPLRQTRTRKPFPESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
DAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELRRSLLSGWVDACCRLLSPLEEALHGYVMT
DGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNAGSALAPAVWFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELY
RNGGITEAACWAHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWLREKMKT
LSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKNFLFFGSDHGGERGALLYSLIGTCKLNDVDP
ESYLRHVLGVIADWPVNRVSELLPWRIALPAE
>SEQF1516_EDU87268.1 hypothetical protein ECH7EC4501_3409 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNQPFRQQNPGIVQHAGSWIKHLIATVFTFRASPKDRSIDFV
>SEQF1516_EDU87269.1 tellurium resistance protein TerZ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSLVKNQTVSLSKESSALSQLHFGLGWDPVKKKGLLGGLFGGNDSIDLDAGCVLMDSTGKTIDTIWFRKLKSTCGAVVH
SGDNLTGEGDGDDEVIKVNLSRLPANVEYLAFTVNSFRGQSFNDVENAFCRVVDQTGKELARYKLTEQGSHTGIVISSLR
RNNGNWDFTALGHACRGRTIDDMHSDIVSAVIR
>SEQF1516_EDU87270.1 integrase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVLTDTKARHIKPDDKPLPHGGITGLTLHPSSVKGRGKWVFRYVSPVTQKRRNAGLGTYPEVSIAEAARTARIMREQLA
AGDDPLEIKKAESEKVAIPTFADAARRVHAELSPGWENPKHVRQWLSTLENYAFPQLGAKTLDSITAADVAETLRPVWLT
LSETASRVKQRIHVVMQWGWAHGFCVANPVDVVDHLLPQQTRGRDEHQPAMPWRQLPLFVATSVYTDEPYNVTRALLLMV
ILTATRSGEARGMRWAEIDFHKRVWTIPAERMKARIQHRVPLSRQAIYILENIRGLHDELVFPSPRKQQILSDMVLTSFL
RKKKAVSDIPGRVATAHGFRSTFRDWCSEQGYSRDLAERALAHTLKNKVEAAYHRTDLLEQRVPMMQAWADYVMSQIVNK
>SEQF1516_EDU87271.1 putative antitoxin module of toxin-antitoxin system [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRPCFGARLVQEGNRLHYLADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTSGELNPRYQHTVTLNAKGLTCEADTLG
SCGYVYLAVYPTPAPATTS
>SEQF1516_EDU87272.1 IS1203 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU87273.1 transposase OrfA, ISEc8 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKLASQPGASVARIAREHDINDNLLFKWLRLWQNERRISRRLPVTTSSGAGVELLPVEITPDEQKEPMAALTPLLSTPS
QSTVSASSCKVEFRHGNMTLENPSPELLTVLIRELTGRGR
>SEQF1516_EDU87274.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSLTTETALDILIAWLQDNIDCGSGIIFDNDEDKTDSAALLPCIEQAREDVRTLRHLQLLHQNR
>SEQF1516_EDU87275.1 hypothetical protein ECH7EC4501_3483 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIHNSSSAFSISDEINMKITIYDNYYNNGFNWNTYITTYYI
>SEQF1516_EDU87276.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQRKVNRSDSDYHYAKEKYKRNIYKMMLECKNEEIKSGEKSDYFKVFS
>SEQF1516_EDU87277.1 hypothetical protein ECH7EC4501_3564 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCFSKLGSSPFDEKTITLSCFFESLFQLIFRDFLLRQVIGFAAIIFADIP
>SEQF1516_EDU87278.1 putative beta-ketoacyl-[acyl carrier protein] synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTNRKRVVITGLGILSSLAENIQDFREALLNKKNGVKDSERFAKWFENARAAEVLHDIEYSDLNEDVIDSLDNAALWAY
KVGKDALSQAGLMDSRDTLKETGMIVGVSSAGTEAFLPLFEQRMEDFSLRKALFSGAFSSCCSSVSTLLGLQGGVELVAT
ACTASPNAVGMAFDYIQNGKSKTMLAVGTEPIYLPTFAGFYALNVMHPDTCTPFSGQSGMSIGEGAGAIVLEEYEHAVAR
GATIYGEILSYATSCDAFHETGPDPRASGAVQVMNKAMANAGVTPEQIDYVNAHGTGTEANDRIETLAMKKVFANHDKLL
VSSTKSYFGHNIGAAGIVELIACLATLPDNRVLPTLNFSHARPNCDLDYVPNEFRDRKVNIFMKNNYAFGGNNCCMILSM
EPASIPVSTYDSKRVAISGVGAVSAIGHTLNQVLENIWAQDHHVELGSVTFPDDTLEEAKELLAVLDESNQFAELFDEEY
SFSEATLPETESNFKTFQVSGLEPRKHLRRFDQRKATRGGTFALIALTEALEQAKRKIKRDGDELGMIMGMSRGPQETTY
KYLQSLKPDPRKVRTSEFPGSLMNAIPTFCGISEGIKGYTTTLATGENSALGALTYGYEIVRQNLQPQVLVGGADEYFPS
MSLYMDAVTQKIHMTAEASDYQIYGKDPQGYVPGEGACMLLLEDPQLAVARGAEVLAEVVGYGKSCSNTYFDASLLEEKS
ASMALAIERALTHAGISAGDIDLVCGTSNGSDDHSRIEIDAIYNTFAAQNPAVPVVNYNACFGFVASAAGLLNLAVITDC
IKKQAVPAIPNTVEFFDERVNFVRQSMKLALNHVLLVGATEGGNYYAFVIKG
>SEQF1516_EDU87279.1 TerF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLQSGQNIPLQQSTIRLNLQYPAKSGFKGEPDTCLFMLNAQGKVSGDSDFIFYNNLSSPEGAVRLVTGSQQASIEIALD
RVPANVSKIAITVVIDGEDTIS
>SEQF1516_EDU87280.1 site-specific recombinase, phage integrase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVWYQTLQEYEQLDYRTLSDCAPLLAGEGMISLSNFAQSIELPISQLIREVVNRNLPVFWLATGQFGFYVDEFNAVERE
PGAKREKQSDDEKDQPKEVIILNSAFELGIESFANGYLRPFNPRHTLDCLLSAGVSEGEAAFRTSGDNQSGGWFFDLPGV
DITADSLLISKVHAEGLRLTWLVKTTPPAVSIHPAVPLVAPVIANEYVHRKHYNENLSWLREEYLKHRRKGKVSEAALRD
IRYYFDLMIEVMGDIQLEDFDRDFLRAYESKLRTIPANRNLMKGKHGVKTLDELIAKAAECGDKLMTEESVKKYINGLYG
AMEWAVDDGKFLKSPCDNFFPPDDKGEREQDHTDIFEPHEIKAIFSQPWFVAGTVERNAQGRFHQYCPFHYWAPLLGLMT
GARVNEIAQLMLDDVLADDGVYYLNLESDSENGKKLKNANSRRKIPVHSTLIELGFIEYVDALKAAGYDRLFPELKPHKT
KGYGRPVSAWFNESLLAGRLKLERDRSKSFHSFRHSVSTLLKEKGVSSELRGQLLGHVRGKTETEVRYSKDLKPVHMVEV
VEKIDFSLPEIARFNIPDGLDAVRDALRRKRGKQTG
>SEQF1516_EDU87281.1 anaerobic ribonucleoside-triphosphate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPHVMKRDGCKVPFKSERIKEAILRAAKAAEVDDADYCATVAAVVSEQMQGRNQVDINEIQTAVENQLMSGPYKQLARA
YIEYRHDRDIEREKRGRLNQEIRGLVEQTNASLLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASHIYGGTTINRIDEVLAPFVTASY
NKHRKTAEEWNIPDAEGYANSRTIKECYDAFQSLEYEVNTLHTANGQTPFVTFGFGLGTSWESRLIQESILRNRIAGLGK
NRKTAVFPKLVFAIRDGLNHKKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQIH
DGRNNLGVISLNLPRIALEAKGDEATFWKLLDERLVLARKALMTRIARLEGVKARVAPILYMEGACGVRLNADDDISEIF
KNGRASISLGYIGIHETINALFGGEHVYDNEQLRAKGIAIVERLRQAVDQWKEETGYGFSLYSTPSENLCDRFCRLDTAE
FGVVPGVTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDVWDYSYQHVPYYGTNTP
IDECYECGFTGEFECTSKGFTCPKCGNHDASRVSVTRRVCGYLGSPDARPFNAGKQEEVKRRVKHLGNGQIG
>SEQF1516_EDU87282.1 multidrug resistance protein MdtM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRFFARHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFNADVSLAPAAVSLYLAGGMALQWLLGPLSDRIGRKPV
LITGALIFTLACAATMFTTSMTQFLIARAIQGTSICFIATVGYVTVQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAAL
MHFVHWKVLFAIIAVMGFISFVGLLLAMPETVKRGAVPFSAKSVLRDFRNVFCNRLFLFGAATISLSYIPMMSWVAVSPV
ILIDAGGLTTSQFAWTQVPVFGAVIVANAIVARFVKDPTEPRFIWRAVPIQLVGLALLIIGNLLSPHVWLWSVLGTSLYA
FGIGLIFPTLFRFTLFSNNLPKGTVSASLNMVILMVMSVSVEIGRWLWFNGGRLPFHLLAVVAGVIVVFTLAGLLNRVRQ
HQAAELAEEQ
>SEQF1516_EDU87283.1 HSP20-like domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDTHSIAQPFEAEVSPANNRQLTVSYASRYPDYSRIPAITLKGQWLEAAGFATGTVVDVKVMEGCIVLTAQPPAAAESE
LMQSLRQVCKLSARKQRQVQEFIGVIAGKQKVA
>SEQF1516_EDU87284.1 trehalose operon repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSQRTRERVEAVMNQHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLA
VQTMLPAFYEQGYDPIMMESQFSPQLVAEHLGVLKRRNIDGVVLFGFTGITEEMLAHWQSSLVLLARDAKGFASVCYDDE
GAIKILMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAHKLHPVAALPGLAMKQGYENVAKVITPETTALLCAT
DTLALGASKYLQEQRIDTLQLASVGNTPLMKFLHPEIVTVDPGYAEAGRQAACQLIAQVTERSEPQQIIIPANLS
>SEQF1516_EDU87285.1 outer membrane protein, OMP85 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRYIRQLCCVSLLCLSGSAVAANVRLQVEGLSGQLEKNVRAQLSTIESDEVTPDRRFRARVDDAIREGLKALGYYQPTIE
FDLRPPPKKGRQVLIAKVTPGVPVLIGGTDVVLRGGARTDKDYLKLLDTRPAIGTVLNQGDYENFKKSLTSIALRKGYFD
SEFTKAQLGIALGLHKAFWDIDYNSGERYRFGHVTFEGSQIRDEYLQNLVPFKEGDEYESKDLAELNRRLSATGWFNSVV
VAPQFDKARETKVLPLTGVVSPRTENTIETGVGYSTDVGPRVKATWKKPWMNSYGHSLTTSTSISAPEQTLDFSYKMPLL
KNPLEQYYLVQGGFKRTDLNDTESDSTTLVASRYWDLSSGWQRAINLRWSLDHFTQGEITNTTMLFYPGVMISRTRSRGG
LMPTWGDSQRYSIDYSNTAWGSDVDFSVFQAQNVWIRTLYDRHRFVTRGTLGWIETGDFDKVPPDLRFFAGGDRSIRGYK
YKSIAPKYANGDLKGASKLITGSLEYQYNVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGVGVRWESPVGPIKLDFAVPVA
DKDEHGLQFYIGLGPEL
>SEQF1516_EDU87286.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKLIELRRAKMLALSLLLIAAATFVVTLFLPPNFWVSGVKAIAEAAMVGALADWFAVVALFRRVPIPIISRHTAIIPRN
KDRIGENLGQFVQKKFLDTQSLVALIRRHEPALLIGNWFSQPENARRVGQHLLQIMSGFLELTDDARIQRLLKRAVHRAI
DKVDLSGTSALMLESMTKNDRHQVLLDTLIAQLIALLQRDKSRKFIAQQIVRWLESEHPLKAKILPTEWLGEHSAELVSD
AVNSLLDDISRDRAHQIRHAFDRATFALIDKLKNDPEMTARADAVKSYLKEDEAFLSELWGDLREWLKADINSEDSRVKE
RIARAGQWFGETLIADDALRASLNGHLEQAAHRVAPEFSAFLTRHISDTVKSWDARDMSRQIELNIGKDLQFIRVNGTLV
GGCIGLILYLLSQLPALFPLGNF
>SEQF1516_EDU87287.1 ribosomal protein S18 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRITGTRAKYQRQLARAIKRARYLSLLPYTDRHQ
>SEQF1516_EDU87288.1 DNA polymerase III, chi subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPV
EIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>SEQF1516_EDU87289.1 putative transcriptional regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQVSLSQQLKEGNLFAEQCPSREVLKHVTSRWGVLILVALREGTHRFSDLRRKIGGVSEKMLAQSLQALEQDGFLNRIA
YPVVPPHVEYSLTPLGEQVSEKVAALADWIELNLPEVLAVRDERAA
>SEQF1516_EDU87290.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNIAPQSPVMRRLTLQDNPAIARVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPL
AGSESDICELQKMYFLPAIRGKGLAKKLALKAMEEAREMGFKRCYLETTAFLKEAIGLYEHLGFQHIDYALGCTGHVDCE
VRMLREL
>SEQF1516_EDU87291.1 pemI protein 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQMRITIKRWGNSAGMVIPNIVMKELNLQPGQSVEVQVSNNQLILTPISRRYSLDELLAQCDMNAAELSEQDVWGKSTPA
GDEIW
>SEQF1516_EDU87292.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLIALPIAWLGRVRLRQLARRDWLTALMLTMMGNLIYYF
CLASAIQRTGAPVSTMIIGTLPVVIPVFANLLYSQRDGKLAWGKLAPALICIGIGLACVNIAELNHGLPNFDWARYTSGI
VLALVSVVCWAWYALRNARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNTQTPDFSLPFGPRPLVFISLMIAI
AVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGLLYTFLLRQQMPPLMTLSGIALLVIGVVIAVRAKPEKPLTESVSE
S
>SEQF1516_EDU87293.1 ribosomal protein L9 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNIEFFEARRAELEAKLAEVLAAANARAEKINALETVTI
ASKAGDEGKLFGSIGTRDIADAVTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE
>SEQF1516_EDU87294.1 methyl-accepting chemotaxis protein I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQTIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNN
IGSGSTVAELMQSASISLKQAEKNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQ
DGFEKQYVAYMEQNDRLYDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKP
IEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNA
ENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVA
GEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
DRVTQQNAALVEESAAAAAALEEQASRLTEAVAVFRIQQQQQQQRETSAVVKTVTPATPRKMAVADSGENWETF
>SEQF1516_EDU87295.1 L-ribulose-5-phosphate 3-epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETDERLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHR
RFPLGSEDDAVRAQGLEIMRKAIQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYP
LMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPGVFKNVPFGEGVVDFERCFETLK
QSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMAKAGMVEAA
>SEQF1516_EDU87296.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHSENQSKGVHYAKSQRLLEINHAHLQLMESLLDEGKKYNIFKPDIDPLQVNINIAALGGYYLINQHTLGLVYPVRRKTP
SFRAGIYGAVFHLTRCLLLFNVLTDGGYWRTSAATGKIARTPQNAFVVIPDCNIWSISSQ
>SEQF1516_EDU87297.1 phospholipase/carboxylesterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEIESRELADIPVLHAYPVGQKDTPLPCVIFYHGFTSSSLVYSYFAVALAQAGLRVIMPDAPDHGSRFSGDAARRLNQF
WQILLQSMQEFTTLRAAIAEEKWLLDDRLAVGGASMGAMTALGITARHPTVRCTASMMGSGYFTSLARSLFPPLIPETVA
QQNEFNNIVAPLAEWEATNHLEQLSDRPLLLWYGLDDDVVPADESLRLQQALSETGRDKLLTCSWQPGVRHRITPEALDA
AVTFFRQHL
>SEQF1516_EDU87298.1 ascorbate-specific phosphotransferase enzyme IIA component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLRDSLAENKSIRLQAEAETWQEAVKIGVDLLVAADVVEPRYYQAILDGVEQFGPYFVIAPGLAMPHGRPEEGVKKTGF
SLVTLKKPLEFNHDDNDPVDILITMAAVDANTHQEVGIMQIVNLFEDEENFDRLRACRTEQEVLDLIDRTNAAA
>SEQF1516_EDU87299.1 putative sugar ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTDQHQEILRTEGLSKFFPGVKALDNVDFSLRRGEIMALLGENGAGKSTLIKALTGVYHADRGTIWLEGQAISPKNTAH
AQQLGIGTVYQEVNLLPNMSVADNLFIGREPKRFGLLRRKEMEKRATELMASYGFSLDVREPLNRFSVAMQQIVAICRAI
DLSAKVLILDEPTASLDTQEVELLFDLMRQLRDRGVSLIFVTHFLDQVYQVSDRITVLRNGSFVGCRETCELPQIELVKM
MLGRELDTHALQRAGRTLLSDKPVAAFKNYGKKGTIAPFDLEVRPGEIVGLAGLLGSGRTETAEVIFGIKPADSGTALIK
GKPQNLRSPHQASVLGIGFCPEDRKTDGIIAAASVRENIILALQARRGWLRPISRKEQQEIAERFIRQLGIRTPSTEQPI
EFLSGGNQQKVLLSRWLLTRPQFLILDEPTRGIDVGAHAEIIRLIETLCADGLALLVISSELEELVGYADRVIIMRDRKQ
VAEIPLAELSVPAIMNAIAA
>SEQF1516_EDU87300.1 transcriptional repressor NsrR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVKIINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVV
RELEPLSLVNCSSEFCHITPACRLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE
>SEQF1516_EDU87301.1 beta-aspartyl peptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIDYTAAGFTLLQGAHLYAPEDRGICDVLVANGKIIAVASNIPSDIVPDCTVVDLSGQILCPGFIDQHVHLIGGGGEAGP
TTRTPEVALSRLTEAGVTSVVGLLGTDSISRHPESLLAKTRALNEEGISAWMLTGAYHVPSRTITGSVEKDVAIIDRVIG
VKCAISDHRSAAPDVYHLANMAAESRVGGLLGGKPGVTVFHMGDSKKALQPIYDLLENCDVPISKLLPTHVNRNVPLFEQ
ALEFARKGGTIDITSSIDEPVAPAEGIVRAVQAGIPLARVTLSSDGNGSQPFFDDEGNLTHIGVAGFETLLETVQVLVKD
YDFSISDALRPLTSSVAGFLNLTGKGEILPGNDADLLVMTPELRIEQVYARGKLMVKDGKACVKGTFETA
>SEQF1516_EDU87302.1 soluble cytochrome b562 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDNLKVVEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEM
KDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNSYHKKYR
>SEQF1516_EDU87303.1 transcriptional regulator, GntR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRSQNLRHNVINQVIDDMARGHIPSPLPSQSALAEMYNISRTTVRHILSHLRECGVLTQVGNDYVIARKPDHDDGFACT
TASMSEQNKVFEQAFFTMINQRQLRPGETFSELQLARAAGVSPVVVREYLLKFGRYNLIQSEKRGQWSMKQFDQSYAEQL
FELREMLETHSLQHFLNLPDHDPRWLQAKTMLERHRLLRDNIGNSFRMFSQLDRDFHSLLLSAADNIFFDQSLEIISVIF
HFHYQWDESDLKQRNIIAVDEHMTILSALICRSDLDATLALRNHLNSAKQSMIRSINENTRYAH
>SEQF1516_EDU87304.1 type 1 fimbriae regulatory protein FimB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNKADNKKRNFLTHSEIESLLKAANTGPHAARNYCLTLLCFIHGFRASEICRLRISDIDLKAKCIYIHRLKKGFSTTHP
LLNKEVQALKNWLSIRTSYPHAESEWVFLSRKGNPLSRQQFYHIISTSGGNAGLSLEIHPHMLRHSCGFALANMGIDTRL
IQDYLGHRNIRHTVWYTASNAGRFYGIWDRARGRQRHAVL
>SEQF1516_EDU87305.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELTMKQLLASPSLQLVTYPASATAQSAEFASADCVTGLNEIGQISVSNISGDPQDVERIVALKADEQGASWYRIITMYE
DQQPDNWRVQAILYA
>SEQF1516_EDU87306.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDGVMLDSDVIAGLEWLASTQENKQHFYQRLAKAQQFYIATTQKAANFGKQFDPEWYGSDVVAGYFAQAKSLIDNRRSY
EVTNASNIIPWVKQLGVCAKSLDRITGARDRAIRMLKNTTVLPDTALLELVLAGNYASEGYEVEFIPEQKGIAKTPEFRC
RLGDGDYFFVECKRLQKGPYVKQEILQHHIRSHLAELHIKSKKMNVWTDVTYLCEVKDAPENYIISHLKNFKGVFYEWND
DYGKGTIRPANLNLIREDITENGSLLVNTKLARLIKGSPLEDENYQVVAMGRPDERDSRFITKVKLASLITWRCINEKSF
DARSRHVTKTLAEIDNQLLDYGLGVGHIALDVDIQKDVADKRREKNYAAIVNFEQKSKIVRLNVHYLVPRIDENSAWMVD
ETADDFFTHDLVKYVIPLTKIFPEAEVFENDQPGWHQN
>SEQF1516_EDU87307.1 fructuronate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTIVDSNLPVARPSWDHSRLESRIVHLGCGAFHRAHQALYTHHLLESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYT
VAEKGAESTELKIIGSMKEALHPEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKS
AIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENVTFPCTMVDRIVPAATPETLQEI
ADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKVGAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTMTN
PDYRKAAFALMMQEQAPTLSMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQNGGSWRHLA
LGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKINAQYQGADRVKALLGLSGIFADDLPQNADFVGAVTAAYQQLCERGAR
ECVAAL
>SEQF1516_EDU87308.1 putative sugar ABC transporter, periplasmic sugar-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWKRLLVVSAVSAAMSSMALAAPLTVGFSQVGSESGWRAAETNVAKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGV
DAIFIAPVVATGWEPVLKEAKDAEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVG
ASVAIDRKKGFAEAIKNAPNIKIIRSQSGDFTRSKGKEVMESFIKAENNGKNICMVYAHNDDMVIGAIQAIKEAGLKPGK
DILTGSIDGVPDIYKAMMDGEANASVELTPNMAGPAFDALEKYKKDGTMPEKLTLTKSTLYLPDTAKEELEKKKNMGY
>SEQF1516_EDU87309.1 RNA chaperone Hfq [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTS
SNYHHGSSAQNTSAQQDSEETE
>SEQF1516_EDU87310.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTWNPLALATALQTVPEQNIDVTNSENALIIKMNDYGDLQINILFTSRQMIIETFICPVSSISNPDEFNTFLLRNQKMMP
LSSVGISSVQQEEYYIVFGALSLKSSLEDILLEITSLVDNALDLAEITEEYSH
>SEQF1516_EDU87311.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGSLFNIYKDIFPTLGMYSGLKACHEKNNLPFDINTEIETIQKQINYDINHLNDGLIKRVLNLFIHLISNPDNLELTLNR
YSSTTEQIIGRTKRNGLHEFDDGDLKIIFNRQDDNESVLTVKDKDKDKDKDKDISHHCNVKTEQLQQFIKIMEQKAQLPI
YIDKNNLKESIFSVLHNDPQQVDKDQHLPCEKFLKHACKSSNSFEVKLDATHQYQHLNNFMISFDPVENQLTIRDNNNKT
ETFSFTNLQWENLLQYYKENHQQPNIAGSRNLTDNIDKIKNTISTSEIIECASPEIRSSVLNDLYSIANFLPDNNLTPNE
SWKRFCETCERFYVAQKSITGDKSERLTRKLSISDAGITMTFKIGDVVINTISTAIPEDATGQRCIEGLNLAEMDLTDID
LSKMALRNVNFNGSILRNAKFSGTICEGVDFTDCDLRNAEFENASLENNDFRKVRHLTYVNFKNANLRNSNFNGKVLTGV
TFTGSDLSNAYLEHIDFTTVILYETSKIPGIPGTPQIPGTPKVILTGAILNYSDLSGKDLSEYNLTGILCMYTNFSNANL
TNCKISNANFSNAKFYNTNCTGANCSNILFDYAWFDNTIFIKTLFKNTCFYNVRAKNVYLEGAYLNNDNIVNQANNSTEK
QSIDSTDKQANDSTVQQSIDSTVQQANDSTDKQANDNIDKQVNDSTDKQAKNSTEQQDSNSFNQARLKKEVNRRFSIPGL
TSYQPTYIVEE
>SEQF1516_EDU87312.1 HflC protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNKPLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFV
TKEKKDLIVDSYIKWRISDFSRYYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSA
GTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTEVSEAIYNRMRAEREAVARRHRS
QGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGDAEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDS
DFFRYMKTPTSATR
>SEQF1516_EDU87313.1 PspA/IM30 family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGILKSLFTLGKSFISQAEESIEETQGVRMLEQHIRDAKAELDKAGKSRVDLLARVKLSHDKLKDLRERKASLEARTLEA
LSKNVNPSLINEVAEEIARLENLITAEEQVLSNLEVSRDGVEKAVAATAQRIAQFEQQMEVVKATEAMQRAQQAVTTSTV
GASSSVSTAAESLKRLQTRQAERQARLDAAAQLEKVADGRDLDEKLAEAGIGGSNKSSAQDVLARLQRQQGE
>SEQF1516_EDU87314.1 high-affinity gluconate transporter GntP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHVLNILWVVFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGMDLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVD
SGAAHQIAHTLLARLGLRYVQLSVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQ
PGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVDMNNLPSFGVSILVPLIPAIIMI
STTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVAFVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTII
DTGIGDTIGMLMSHGNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLATAAGSNTLT
HINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA
>SEQF1516_EDU87315.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDIL
SECALNADLIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH
>SEQF1516_EDU87316.1 putative sugar ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKRNLPLMITIGVFVLGYLYCLTQFPGFASTRVICNILTDNAFLGIIAVGMTFVILSGGIDLSVGSVIAFTGVFLAKVI
GDFGLSPLLAFPLVLVMGCAFGAFMGLLIDALKIPAFIITLAGMFFLRGVSYLVSEESIPINHPVYDTLSSLAWKIPGGG
RLSAMGLLMLAVVVIGIFLAHRTRFGNQVYAIGGNATSANLMGISTRSTTIRIYMLSTGLATLAGIVFSIYTQAGYALAG
VGVELDAIASVVIGGTLLSGGVGTVLGTLFGVAIQGLIQTYINFDGTLSSWWTKIAIGILLFIFIALQRGLTVLWENRQS
SPVTRVNIAQQ
>SEQF1516_EDU87317.1 protein fimG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKWRKRGYLLAAILALASATIQAADVTITVNGKVVAKPCTVSTTNATVDLGDLYSFSLMSAGAASAWHDVALELTNCPVG
TSRVTASFSGAADSTGYYKNQGTAQNIQLELQDDSGNTLNTGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQAVI
SITYTYS
>SEQF1516_EDU87318.1 magnesium-translocating P-type ATPase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLKMAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENK
LPAQQPSPWWVHLWVCYRNPFNILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLPVEKAATTRQPEHSNPLECDTLC
FMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQESEPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALF
ALSVAVGLTPEMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDISGKTSERVL
HSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERRRMSVVVAENTEHHQLVCKGALQEILNVCSQ
VRHNGEIVPLDDIMLRKIKRVTDTLNRQGLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKA
SGITVKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKERIVTLLKREGHVVGFMG
DGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFL
PFLPMLPLHLLIQNLLYDVSQVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPETQT
LFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQALPLSYFPWLVAILAGY
MTLTQLVKGFYSRRYGWQ
>SEQF1516_EDU87319.1 glutathionylspermidine synthase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRHNVPVRRDLDQIAADNGFDFHIIDNEIYWDESRAYRFTLRQIEEQIEKPTAELHQMCLEVVDRAVKDEEILTQLAIP
PLYWDVIAESWRARDPSLYGRMDFAWCGNAPVKLLEYNADTPTSLYESAYFQWLWLEDARRSGIIPRDADQYNAIQERLI
SRFSELYSREPFYFCCCQDTDEDRSTVLYLQDCAQQAGQESRFIYIEDLGLGVGGVLTDLDDNVIQRAFKLYPLEWMMRD
DNGPLLRKRREQWVEPLWKSILSNKGLMPLLWRFFPGHPNLLASWFEGEKPQIAAGESYVRKPIYSREGGNVTIFDGQNN
VVDHADGDYADEPMIYQAFQPLPRFGDSYTLIGSWIVDDEACGMGIREDNTLITKDTSRFVPHYIAG
>SEQF1516_EDU87320.1 carbon starvation family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILGIIGAFCLAVVALRRGEHVSALWIVVASVSVYLVAYRYYSLYIAQKVMKLDPTRATPAVINNDGLNYVPTNRYVLFG
HHFAAIAGAGPLVGPVLAAQMGYLPGTLWLLAGVVLAGAVQDFMVLFISSRRNGASLGEMIKEEMGPVPGTIALFGCFLI
MIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFIRPGRVGEVSVIGIVLLVASIYFGGVIAHDPYWGPALT
FKDTTITFALIGYAFVSALLPVWLILAPRDYLATFLKIGVIVGLALGIVVLNPELKMPAMTQYIDGTGPLWKGALFPFLF
ITIACGAVSGFHALISSGTTPKLLANETDARFIGYGAMLMESFVAIMALVAASIIEPGLYFAMNTPPAGLGITMPNLHEM
GGENAPIIMAQLKDVTAHAAATVSSWGFVISPEQILQTAKDIGEPSVLNRAGGAPTLAVGIAHVFHKVLPMADMGFWYHF
GILFEALFILTALDAGTRSGRFMLQDLLGNFIPFLKKTDSLVAGIIGTAGCVGLWGYLLYQGVVDPLGGVKSLWPLFGIS
NQMLAAVALVLGTVVLIKMKRTQYIWVTVVPAVWLLICTTWALGLKLFSTNPQMEGFFYMASQYKEKIANGTDLTAQQIA
NMNHIVVNNYTNAGLSILFLIVVYSIIFYGFKTWLAVRNSDKRTDKETPYVPIPEGGVKISSHH
>SEQF1516_EDU87321.1 HNH nuclease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASSKSLQQAIANIKIWHKGEQRAPHKPLLLLYVLAGYLNGHPRLFDYGTEIYEPLHSLLERFGPQRSQYRPDMPFWRLQ
GDGIWQLHNAERCSTAGSSRQPPVKELNEYHVAGGFDEQHYALVTGNKKLINTLAQQILEAHFTESIQEEIADELGFDLQ
QTRKQRDPLFRKNVLRAYNYQCAICGFNMRHDDTTVALEAAHIKWKQHGGPCEIPNGLALCAIHHKAFDKGSIGLDENMR
VLVSDAVNGGGIVERLFWDFDGKTIALPQVRKNYPYEGFVGER
>SEQF1516_EDU87322.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIHILGICGTFMGGLAMLARQLGHEVTGSDANVYPPMSTLLEKQGIELIQGYDASQLDPQPDLVIIGNAMTRGNPCVEA
VLEKNIPYMSGPQWLHDFVLRDHWVLAVAGTHGKTTTAGMATWILEQCGYKPGFVIGGVPGNFEVSARLGESDFFVIEAD
EYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRIIWPENDINLKQTMAMGCWSEQEL
VGEQGHWQAKKLTTDASEWEVLLDGEKVGEVKWSLVGEHNMHNGLMAIAAARHVGVAPADAANALGSFINARRRLELRGE
ANGVTVYDDFAHHPTAILATLAALRGKVGGTARIIAVLEPRSNTMKMGICKDDLAPSLGRADEVFLLQPAHIPWQVAEVA
EACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLAKKAEAAQ
>SEQF1516_EDU87323.1 RNA methyltransferase, TrmH family, group 3 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALESQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQY
QENDLPDLIASLDQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLART
MRMLQEENIWIVGTAGEADHTLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGICLFEAVR
QRS
>SEQF1516_EDU87324.1 IS1203 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU87325.1 type I restriction-modification system, R subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAELNLSNLTEADIITKCVMPAILNAGWDNTTQIRQEVKLRDGKVIVRGKVAARRTVKSADIVLYHKPGIPLAVIEAKAN
KHEIGKGMQQGIEYARLLDVPFVFATNGDGFIFRDATAAEGECLEKQITLDDFPSPAELWQKFCLWKGYTQAQLPVITQD
YYDDGSGKSPRYYQLQAINKTIEAVSNGQNRVLLVMATGTGKTYTAFQIIWRLWKSKNKKRILFLADRNILVDQTKNNDF
QPFGTAMTKVSGRTIDPAYEIHLALYQAITGPEEDQKAFKQVAPDFFDLIVIDECHRGSASEDSAWREILDYFSSATQIG
LTATPKETHEVSSTDYFGDPVYVYSLKEGIEDGFLAPYKVVRVDIDVDLQGWRPTKGQTDLNGEVIDDRIYNQKDFDRTM
VIDERTELVARTITDYLKRTNPMDKTIVFCNDIDHAERMRRALVNLNPEQVKKNDKYVMKITGDDEIGKAQLDNFINPKK
PYPVIATTSELMTTGVDAKTCKLVVLDQNIQSMTKFKQIIGRGTRIDERYGKLWFTILDFKKATELFADERFDGIPEKVM
DTTPEDIADPESDFEEKLEEISEHDDEQVTGVDEPPAPPYQVKDTDDVGPLPEEDEKKIRKFHVNGVAVGVIAQRVQYYD
ADGKLVTESFKDYTRKTLLKEYASLDDFTRKWQDADRKEAIIHELEQQGIIWEVLAEEVGKDLDPFDMLCHVVYGQPPLT
RKERAENVRKRNYFTKYSEAAQAVLDNLLDKYADAGVQEIESIQVLKLKPFDSMGTLPEIIKTGFGDRNGYNQALSELEN
EIYQLPPRSA
>SEQF1516_EDU87326.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSRVLALLAVLLLSANTWAAIEINNHQARNMDDVQSLGVIYINHNFATESEARQALNEETDAQGATYYHVILMREPGSN
GNMHASADIYR
>SEQF1516_EDU87327.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSRKRNSVIYRFASLLLVLMLSACSALQGTPQPAPPVTDHPQEIRRDQTQGLQRIGSVSTMVRGSPDDALAEIRAKAVA
AKADYYVVVMVDETIVTGQWYSQAILYRK
>SEQF1516_EDU87328.1 hypothetical protein ECH7EC4501_2812 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNYGGHMYAVVLPNFRTLYQYNGKHITPVHQLRIMNGD
>SEQF1516_EDU87329.1 acyl-CoA dehydrogenase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLASIGQQLGTAESLELGRLANVNPPELLRYDAQGRRLD
DVRFHPAWHLLMQALCTNRVHNLAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPAPFQDWTTPL
LSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFSVPQSDAHLVLAQTAGGLSCFFV
PRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDAIGWLLGQEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYH
AHQRHVFGNPLIQQPLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPFVAEAMEVL
GGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLSEAFVEVKGQDRYFDCAVRRLQQQLRKPAEE
LGREITHQLFLLGCGAQMLKYASPPMAQAWCQVMLDTRGGVRLSEQIQNDLLLRATGGVCV
>SEQF1516_EDU87330.1 2',3'-cyclic-nucleotide 2'-phosphodiesterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKDTATEKFGLVRTASLINNARNEVKNSVLVDNGDLIQG
SPLADYMSAKGLKAGDIHPVYKALNTLDYTVGTLGNHEFNYGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKDT
EVVDKDGKKQTLKIGYIGVVPPQIMGWDKANLSGKVTVNDITETVRKYEPEMREKGADVVVVLAHSGLSADPYKVMAENS
VYYLSEIPGVNAIMFGHAHAVFPGKDFADIEGADITKGTLNGVPAVMPGMWGDHLGVVDLQLSNDSGKWQVTQAKAEARP
IYDIANKKSLAAEDSKLVETLKADHDATRQFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQGDPDLAKL
PVLSAAAPFKVGGRKNDPASYVEVEKGQLTFRNAADLYLYPNTLIVVKASGKEVKEWLECSAGQFNQIDPNSTKPQSLIN
WDGFRTYNFDVIDGVNYQIDVTQPARYDGECQMINANAERIKNLTFNGKPIDPNAMFLVATNNYRAYGGKFAGTGDSHIA
FASPDENRSVLAAWIADESKRAGEIHPAADNNWRLAPIAADKKLDIRFETSPSDKAAAFIKEKGQYPMNKVATDDIGFAI
YQVDLSK
>SEQF1516_EDU87331.1 type-1 fimbrial protein homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFALAGNKWNTTPPGGNMQFQGVIIAETCLIEAGDKQMTVNMGQISSNRFHAVGEDSAPVPFVIHLRECSTVVSERVGVA
FHGVADGKNPDVLSVGEGPGIATNIGVALFDDEGNLVPINRPPANWKRLYSGSTSLHFIAKYRATGRRVTGGIANAQAWF
SLTYQ
>SEQF1516_EDU87332.1 DEAD/DEAH box helicase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPSVVSRQVADSVAAFLRAAFPLNSPLFNGENNDNVSMLEQFLAQPETLLKGPYLSAQLPFRKSDLPLNFFPNLTLPFP
PHAHQARAFQRLGSDAPQPTLVATGTGSGKTECFMFPLLNHCAGASQAGVKAIIIYPMNALATDQASRFAKTIASDPQLH
GKVTVGLFVGDSEIEPSKKMSAEKVITCKHTLRESPPDILLTNYKMLDYLLMRPGDQPLWRYNQPGSLRYLVVDELHTFD
GAQGSDLACLVRRLKHHIGVDNQRFACVGTSATVGDELGQLLDYAKTIFDQPFTDDAVIREDRYTAAEYLQNYAIAYSQY
PGPEVASALDPQSYATPVAYLNGQIPLWFPDSDLQLPDDLESDDGREKRIALGSLLRRHSVMHVLLHDLQGGILSERECL
ENLQVMLAESADHARRVLQSILALIAQARLEVPETEHDRQKRLQAKKARPVLPFVQLRSQLWLREMRRLVASVAKTPRLV
FADDVAVEDREHYLPVIHCRDCHATGWASLRHGQSVQLETDLDGIYRQFFEKGRSIVLAFPDNNEKAVSGAHQKLCPTCL
KLNRQSSVQCGHCGHTELLQVLIPDMLKERKDELEFANECPYCNSKQGISILGSRAASLSAVMIHQLYGSQFNEHKKLIT
FSDSVQDAAHRASFFTARTWPLMIRGQIASVLSEKETLPLDAFAARVCQQTRERSPDDAHFAANVIAPNMQWLNDYQTLK
NEGKLAENSDLPELVSLRLDWEVYSEFTLRARIGRTLEATGYAVAGVDKDRFNPAITALHQQLCEELGDEMSGVSVEQVA
HLALGVIWYQRQAGAVMHPAFESYRRDGTTFMMTQKERTSRYMPSIGPKTRKPAYASFEKINGFHRLIGAKSNPSWYQHW
INRTLSNGNNLFISSVAETVLRRLFTALKIAGVVKDFDTKGREAWGLVPSALVVSRDVVQLNCSCCREVVRAPADQGWQW
RNAPCLSLRCEGRYQEVDNTATWRWENMDIARVQGAEHTGLLSREDREVTEKSFYRGNQPWNINLLSATPTLEMGIDVGD
LSTVLLCSVPPAQANYLQRIGRAGRKDGNALNITVAEGNPHDQFFFEEPLEMMQGQVQAPGVFLNATAILERQLAAFCMD
NWVKTGVPESAICKNVKQMLDELEFGRKSGFPYNLLRYIEQHHAEIAAQFTAIFPDLAAETRQQLLSYLQGAPGQRSLVQ
RIEEALKLLVEDRKSLRSRIDKLKRSIDKLENAPRDQNFDSDMRELTSERQALMALVNQINNKQTLNFLTDEGLLPNYAF
PEAGITLRSVLWRRKEGGEAREYQNTTFEYERPASTALAELAPLNNFYAGGHKVEIEQIDLKVSEPENWRICSHCNYSEN
IDQTGDQHKYCPKCGTPGWADAGQKTTLLKLRQVYARASARDSQISDESDSREPAFFQRQLLVSFEKEDVSAAYAIEEGE
VPFGFEFLSKVTLRDINFGKMADDANELMIAGEAKKRTGFKVCLGCGMVQRPRDHEPRHDLSCKYRTEPEKAKFEDYLYL
YRQLESEALRILLPVSSYSNDRVVEASLGAAIQLGLKHYFKGNVDHLKGVVYREPENEGESWRQYLVIYDTVPGGTGSLK
ELMRTPDNLLKLLELAYQAIVECSCNNDTHKDGCYRCVYAYRDRGRMKYVSRDQARLLLAKILQARDSIRVIDSIKNISL
EAMMGSELEKRFISCLQENKNLIVSRSYAHQGAGWIINTRSEPMMSWHLKAQVDLGAKEAVGIPCRPDYVLYPLMQSDAI
KPVAIFLDGFAFHKNSVAEDVQKRQAIRDSGNFWVWTVTWADLKEPGLKHVQDVLGLGHNPDMKQPKFYNLFHDTNFAAL
EASFRERNSFALLLDYLADPGGRTQLWQRMAAAHAWVWLDVKKSQDAGTKQKYAYEMQENAPAWRLAELLPDEPFVFGGL
LDSCNSSQQFIELASVLPQQAIKPTTSVAQMRSWLRLHICFDDRYTQDDGYEAGLNGFWRLVNLLQFLPDMTFTSRKAVH
LPQESVDTKVSATPEAVPETDESWAEIIEFGLLSAEEIALLQSHSLSAPTLGYELQNDEGEIIAEADLAWPSQKWALIID
NQEFIPLFTTRGWHVAFGPIDENTLQHLSGGDK
>SEQF1516_EDU87333.1 alpha,alpha-phosphotrehalase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTL
DDFDELVTQAKSRGIRIILDMVFNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPDDLDGDGRRFYTDGPRAHEFLHEMNRDV
FTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVALNALF
WCNHDQPRIVSRFGDEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELRNDGRDADE
LLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALADESSVFYTYQKLIALRKQEAILTWGNYQDL
LPNSPVLWCYRREWKGQTLLVIANLSREIQPWQPGQMRGNWQLVMHNYEEASPQPCAMTLRPFEAVWWLQK
>SEQF1516_EDU87334.1 putative transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNSILVILCLIAVSAFFSMSEISLAASRKIKLKLLADEGNINAQRVLNMQENPGMFFTVVQIGLNAVAILGGIVGDAAF
SPAFHSLFSRYMSAELSEQLSFILSFSLVTGMFILFADLTPKRIGMIAPEAVALRIINPMRFCLYVCTPLVWFFNGLANI
IFRIFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTPRENVIWFDLHEDEQSLKNKVAE
HPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSLALNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVV
GIITLNDVMTTLMGDLVGQGLEEQIVARDENSWLIDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRKIPKRTDSV
KFAGYKFEVVDIDNYRIDQLLVTRIDSKATALSPKLPDAKDKEESVA
>SEQF1516_EDU87335.1 fimbrial protein FimF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNKPFYLLCAFLWLAVSHALAADSTITIRGYVRDNGCSVAAESTNFTVDLMENAAKQFNNIGATTPVVPFRILLSPCGN
AVSAVKVGFTGVADSHNANLLALENTVSAASGLGIQLLNEQQNQIPLNAPSSAISWTTLTPGKPNTLNFYARLMATQVPV
TAGHINATATFTLEYQ
>SEQF1516_EDU87336.1 putative transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQQGDAVAGELATEKVGIKGYLAFFLTIIFFSGVFSGTDSWWRVFDFSVLNGSFGQLPGANGATTSFRGAGGAGAKDGF
LFALELAPSVILSLGIISITDGLGGLRAAQQLMTPVLKPLLGIPGICSLALIANLQNTDAAAGMTKELAQEGEITERDKV
IFAAYQTSGSAIITNYFSSGVAVFAFLGTSVIVPLAVILVFKFVGANILRVWLNFEERRNPTQGAQA
>SEQF1516_EDU87337.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKIYQEKGHQLPHIHIDYGKQAHAASYAIQSGDRIEGDLPKKYDSDVSSWLGRNRDKILEIWNALQAGAPYEPLIAEL
TGGV
>SEQF1516_EDU87338.1 leucyl aminopeptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGK
ERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVG
QGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVL
AGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHN
PLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKG
ATGRPVALLAQFLLNRAGFNGEE
>SEQF1516_EDU87339.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLPTTIYSFPAYLSRFSSTDKPVKLKFHQYARATLLSNRGRDHNCDGRRTVEIHKLDLSDWQAFNKLATKCNAYDGVTM
NGDNSFGWNHEATLDNIHAQKYNKAYAGARLTAELKYLLQDVESFEPNSKYTIHEVVLGPGYGTPDYTGQTIGYVVTLPA
QMPNCWSSELPTIDLYIDQLRTVTGVSNALGFIIAALLNAYSDLPHDLKIGLRSLSSSAAIYSGLGFERVPQERDISCAR
MYLTPANHPDLWTQENGEWIYLRN
>SEQF1516_EDU87340.1 hypothetical protein ECH7EC4501_2794 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRCEESVANKQVESVTIQLSYALECAGTLPGAFFIKGRGFNSAKFGDA
>SEQF1516_EDU87341.1 oxidoreductase, zinc-binding dehydrogenase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSMIKSYAAKEAGGELEVYEYDPGELRPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKG
LQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKP
LLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKALSGQFDLIINTVN
VSLDWQPYFEALTYGGNFHTVGAVLTPLPVPAFTLIAGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDA
IKHVRDGKARYRVVLKADF
>SEQF1516_EDU87342.1 FKBP-type 22 kDa peptidyl-prolyl cis-trans isomerase FklB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTPTFDTIEAQASYGIGLQVGQQLSESGLEGLLPEALVAGIADALEGKHPAVPVDVVHRALREIHERADAVRRQRFQAM
AAEGVKYLEENAKKEGVNSTESGLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIPGWIE
ALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL
>SEQF1516_EDU87343.1 methionine-S-sulfoxide reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGMEIAIFAMGCFWGVERLFWQLHGVYSTAAGYTGGYTPN
PTYREVCSGDTGHAEAVRIVYDPSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAA
MLAADDDRHITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA
>SEQF1516_EDU87344.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKIIGKQLPKKDQDNEHWVSMSDLMAGLMMVFMFISIAYMHYVRIEKEKIKEVAVAYENAQLQLYNALDIEFAKDLQDW
DAEIDKQTLEVRFKSPDVLFGLGSTELKPKFKLILDDFFPRYLKVLDNYQEHITEVRIEGHTSTDWTGTTNPDIAYFNNM
ALSQGRTRAVLQYVYDIKNIATHQQWVKSKFAAVGYSSAHPILDKTGKEDPNRSRRVTFKVVTNAELQIRKIIQE
>SEQF1516_EDU87345.1 chaperone protein FimC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNKNVNVRKSQEITFCLLAGILMFMAMMVAGRAEAGVALGATRIIYPAGQKQVQLAVTNNDENSTYLIQSWVENADGVK
DGRFIVTPPLFAMKGKKENTLRILDATNNQLPQDRESLFWMNVKAIPSMDKSKLTENTLQLAIISRIKLYYRPAKLALPP
DQAAEKLRFRRSANSLTLINPTPYYLTVTELNAGARVLENALVPPMGESTVKLPSDAGSNITYRTINDYGALTPKMTGVM
E
>SEQF1516_EDU87346.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKDAIFSPCGKYRYSLSRVWDESKPYTLFIGLNPSYADAEKDDRTLSRCISFAKSWGYGGVYMANLFAFVHTQRHEMMK
ASDPIGKDNDSHLIRLVSGAGLVVAAWGNEGRHLKRSTTVRQLLPESTMCFVLNATGEPKHPLYMKNDSVLIPLG
>SEQF1516_EDU87347.1 endoribonuclease L-PSP family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVERTAVFPAGRHSLYAEHRYSAAIRSGDLLFVSGQVGSREDGTPEPDFQQQVRLAFDNLHATLAAAGCTFDDIIDVTSF
HTDPEKQFEDIMTVKNEIFSAPPYPTWTAVGVTWLAGFDFEIKVIARIPEL
>SEQF1516_EDU87348.1 (R)-2-hydroxyglutaryl-CoA dehydratase activator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTYSIGIDSGSTATKGILLADGVITRRFLVPTPFRPATAITEAWETLREGLETTPFLTLTGYGRQLVDFADKQVTEISCH
GLGARFLAPATRAVIDIGGQDSKVIQLDDDGNLCDFLMNDKCAAGTGRFLEVISRTLGTSVEQLDCITENVTPHAITSMC
TVFAESEVISLRSAGVAPEAILAGVINAMARRSANFIARLSCEAPILFTGGVSHCQTFARMLESHLRMPVNTHPDAQFAG
TIGAAVIGQRVRTRR
>SEQF1516_EDU87349.1 adenylosuccinate synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTLVINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAAL
MKEMKELEDRGIPVRERLLLSEACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAE
KLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDFVMFEGAQGTLLDIDHGTYPYVT
SSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGAGPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAV
QLNSLSGFCLTKLDVLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGLPQAALNYI
KRIEELTGVPIDIISTGPDRTETMILRDPFDA
>SEQF1516_EDU87350.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLRKILALTCLLLPMMASAHQFETGQRVPPIGITDRGELVLDKDQFSYKTWNSAQLVGKVRVLQHIAGRTSAKEKNATL
IEAIKSAKLPHDRYQTTTIVNTDDAIPGSGMFVRSSLESNKKLYPWSQFIVDSNGVARGAWQLDEESSAVVVLDKDGRVQ
WAKDGALTQEEVQQVMDLLQKLLK
>SEQF1516_EDU87351.1 putative type I restriction-modification system, S subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVEKLIVDHMETWTSALQTRSTAGRGSSGKIDLYGIKKLRELILELAVRGKLVPQDPNDEPASELLKRIAAEKAELVKQ
GKIKKQKPLPEISEEEKPFELPEGWEWVRISEIGHDWGQKTPDKDFTYIDVGSINKEYGIIEELSILSAKDAPSRARKIV
QQGTIIYSTVRPYLLNIAIIENEILPEPIASTAFAIIHPYTAMDANFIYYYLRSPVFVCYVENCQTGVAYPAINDKQFFS
GITPVPPSLEQVRIANKIKELMSLCDQLEQQSLTSLDAHQQLVETLLGTLTDSQTAEELAENWARISEYFDTLFTTEASV
DALKQTILQLAVMGKLVPQDPNDEPASELLKRIAQEKAQLVKEGKIKKQKPLPPISDEEKPFELPEGWEWCLFEDIIDIQ
SGITKGRNLSNRTLVKVPYLRVANVQRGYLDLTEIKQIEIPIEEKEKYQVVKGDLLITEGGDWDTVGRTTVWCHDWYIAN
QNHVFKGRNIGQDVDPYWLETYMNSPFSRQYFANASKQTTNLASINKTQLRGCPVAIPPSSEAKKIMSKLHIFYKLCEEL
KNHIQSAQQTQLHLADALTDAAVN
>SEQF1516_EDU87352.1 putative P-loop hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRVIPLPDEQATLDLGERVAKACDGATVIYLYGDLGAGKTTFSRGFLQALGHQGNVKSPTYTLVEPYTLDNLMVYHFDL
YRLADPEELEFMGIRDYFANDAICLVEWPQQGTGVLPDPDVEIHIDYQAQGREARVSAVSSAGELLLARLAG
>SEQF1516_EDU87353.1 CobW/P47K family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPIAVTLLTGFLGAGKTTLLRHILNEQHGYKIAVIENEFGEVSVDDQLIGDRATQIKTLTNGCICCSRSNELEDALLDL
LDNLDKGNIQFDRLVIECTGMADPGPIIQTFFSHEILCQRYLLDGVIALVDAVHADEQMNQFTIAQSQVGYADRILLTKT
DVAGEAEKLRERLARINARAPVYTVTHGDIDLGLLFNTNGFMLEENVVSTKPRFHFIADKQNDISSIVVELDYPVDISEV
SRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGVQRLYSADWDRPWGDEKPHSTMVFIGIQLPEEEIRAAFAGLRK
>SEQF1516_EDU87354.1 transcriptional regulator, GntR family/aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQQAYQTLETMKLITPQPRSGYFVAQRKAQPPVPPMTR
PVQRPVEITQWDLVLDMLVAHSDSSIVPLSKSTPDVETPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQVARLML
DSGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRGMGVKVIEIPTDPETGISVEALELALEQWP
IKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIVIFEDDVYGELATEYPRPRTIHSWDIDGRVLLCSSFSKSIAPGLR
VGWVAPGRYHDKLMHMKYAISSFNVPSTQMAAATFVLEGHYHRHIRRMRQIYQRNLALYTCWIREYFPCEICITRPKGGF
LLWIELPEQVDMVCVTRQLCRMKIQVAAGSIFSASGKYRNCLRINCALPLSETYREALKQIGEAVYRAME
>SEQF1516_EDU87355.1 hypothetical protein ECH7EC4501_2840 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADYAEINNFPPELSSSGDKYFHLRNYSEYSEYTSGFFLSLMIFIKS
>SEQF1516_EDU87356.1 PTS system, trehalose-specific IIBC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANARPKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALI
ASTGQAQVDKEQVKKAARQNMKWHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFL
WLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDFGMFSIAKVGYQAQVIPALLAGL
ALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHALIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITG
VHQTTLAIDLQMIQSMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGINLKYRFPML
CAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMAIAIIIPIVLTSFIYQRKYRLGTLDIV
>SEQF1516_EDU87357.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAIISPDYYYVLTVAGQSNAMAYGEGLPLPDREDAPHPRIKQLARFAHTHPGGPSCHFNDIIPLTHCPHDVQDMQSYHH
PLATNHQTQYGTVGQALHIARKLLPFIPDNAGILIVPCCRGGSAFTAGSEGTYSERHGASHDACRWGTDTPLYQDLVSRT
RAALVKNPQNKFLGVCWMQGEFDLMTSDYASHPQHFNHMVEAFRRDLKQYHSQLNNITDAPWFCGDTTWYWKENFPHAYE
AIYGNYQNNILANIIFVDFQQQGARGLTNAPDEDPDDLSTGYYGSAYRSPENWTTALRSSHFSSAARRGIISDRFVEAIL
QFWRER
>SEQF1516_EDU87358.1 hypothetical protein ECH7EC4501_2804 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLNGLIHINNIELNSYSEQGLTGFNWFQNPNAVAFT
>SEQF1516_EDU87359.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSTSHPVERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMLAEGEFSFSELSWIASGNYAGYLAGSLLFSFGAFHLPSR
LRPFLLASALATGLLILAMAWLPPFLLVFIIRFLAGVASAGMLIFGSTLIMQHTRHPFVLAALFSGVGVGIALGNEYVLA
GLHFALSSQTLWQGAGALSAIILLALALLIPSNKHVIPPAPLAKIAQQPMSWWLLAILYGLAGFGYIIVATYLPLMAKDA
GQPVLTAHLWTLVGLSIVPGCFGWLWAAKRWGALPCLTANLLVQAICVLLTLASSSPLLLIISSIGFGGTFMGTTSLVMT
IARQLSVPGNLNLLGFVTLIYGIGQILGPALTSMLGNGTSALASATLCGAAALFIAALICGMQIFKLHTNYS
>SEQF1516_EDU87360.1 regulator of cell morphogenesis and NO signaling [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARKELDVEVIEAELAKLAEQPIEKDWRSAPLAEIIDHII
VRYHARHREQLPELILQATKVERVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEH
DEAGELLEVIKHNTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVLFPRALAGE
>SEQF1516_EDU87361.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIG
ALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHSFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWL
VKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMMAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFAS
FICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDPRKD
>SEQF1516_EDU87362.1 hypothetical protein ECH7EC4501_2825 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHHPENTNINKPLQIDFRSDQLQATNQETYFMMRIMLSLMAGKH
>SEQF1516_EDU87363.1 transcriptional regulator, TetR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLV
DILRDDRPVGECLAEVLKEAARRYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETAIYDYIARLHPQSAQCVTDFM
STVMSGLSAKAREGHSLEQLCATAALAGEAIKTILKE
>SEQF1516_EDU87364.1 helix-turn-helix domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKMTLRKLFGQRVKELRIATGMSQEAFADRCGFARSYMSRIERGGSNASLDAIEVLANALSVEPWRLLVSDSSEDSDPEL
LVPYAADGSCFHPGLASTRDGSFGVGDKTAQKRFGTFSEALEYLRSMETAKWRRPNPSGNWGIVSAVRWDKLRK
>SEQF1516_EDU87365.1 transcriptional regulator, GntR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLDVTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSH
NTDSPDANVCNDAGPFELLQARQLLESNIAEFAALQATREDIVKMRQALQLEERELASSAPGSSESGDMQFHLAIAEATH
NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKLAMWQHLENVKQRLLEFSNVDDI
YFDGYLFDSWPLDKVDA
>SEQF1516_EDU87366.1 aspartate carbamoyltransferase, catalytic subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKVIASCFFEASTRTRLSFETSMHRLGASVVGFSDSANT
SLGKKGETLADTISVISTYVDAIVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAM
VGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEEVMAEVDILYMTRVQKERLDPSE
YANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIATDVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL
>SEQF1516_EDU87367.1 helicase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKQNYAPGMRVVIRDAEWRIRRADDSGDGGYLLTCDGISELVRGKEGLFLTKLEQKVEILDPAKTHLVEDESANYQAAQ
LYIESQLRQRVPTDSKVHFGHLAAMDSMPFQLDPTRMALAQPRQRILIADAVGLGKTLEAGILVSELIRRGRGKRILVLA
VKSMLTQFQKEFWSRFAIPLTRLDSAGLQKVRNRIPTNHNPFHYFDKTIISIDTLKQDIEYRHHLENAWWDIIVIDEAHN
VAERGTSSLRSKLAKLLAGRSDTLIMLSATPHDGKAESFASLMNMLDPTAIANPKEYEYADFADKNLVVRRFKKDVKDQM
SGEFPERNIVKLTRLASGAEEEAYRRLVESQFRDDDDEQAQSNKGRLFKITLEKALFSSPMACASVVANRLKRLESRKDH
NSQSQINELESLLLALNNIDASQFSKYQLLLDTIRKDLAWKANNTEDRLVIFTESIKTLEFLEQQLRADLKLKDDQIATL
RGDQGDTVLMETVEAFGKTQSPLRLLVCSDVASEGINLHHLSHKMIHFDIPWSLMVFQQRNGRIDRYGQKHQPQIRYLLT
EASEPQINGDMRVLEVLINKDEQAQKNIGDSSEFTGKFTQEEEEEQVAEFMMQDDGASLFDQLLNSNVSESAEHDLFGEI
CSAVSSDASMVTETDTSLFASEQAYCERALGYLKASGQTIQYETLPDNTLSLVAPEELRRRFNQLPPEIAPENWQLYLSQ
DKTVITDAIARARGEQHAWPDVQYLWQINPVVQWLDDKISSAFGRHQAPVIRLPYLLEPDEDHFILSGLFPNRKSHPMVN
PWIVVSFNRESLIGSQPFAEFLQRHPQLSNKLTNSGGKDRNHQRQQDLLEAAIAHAREVFIHDRNAFETHINQQLNEHLQ
KLDVLRGRQLSQLELDFADNKQQLSVKQSRKEQRQREIEHNFDSYIEWIEDTMTTEKEPYIQVIAVITGAEG
>SEQF1516_EDU87368.1 inorganic diphosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDRFMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPL
QPGSVIRCRPVGVLKMTDEAGEDAKLVAVPHSKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWVKVEGWENAE
AAKAEIVASFERAKNK
>SEQF1516_EDU87369.1 ascorbate-specific permease IIC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKGTIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGIN
GAISDTYASMMATIDRMGDAYSWVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTII
CTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVEDLKLPGWLNIFHDNIVSTAIVM
TIFFGAILLSFGIDTVQAMAGKVHWTVYILQTGFSFAVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYS
FAPNAVVWGFMWGTIGQLIAVGILVACGSSILIILGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEIFGCVWAVK
LTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRALRAEEDAEKQLAEQSA
>SEQF1516_EDU87370.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRLFYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGM
TFSTQPAGTPDTDWLADKDIAFLPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA
>SEQF1516_EDU87371.1 ribosomal protein S6 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGRRQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRF
NDAVIRSMVMRTKHAVTEASPMVKAKDERRERRDDFANETADDAEAGDSEE
>SEQF1516_EDU87372.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIFVYGSLRHKQGNSHWMTNAQLLGDFSIDNYQLYSLGHYPGAVPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQL
IQTPYGSAWMYVYQRPVDGLKLIESGDWLDRDK
>SEQF1516_EDU87373.1 putative 2-hydroxyglutaryl-CoA dehydratase, D-component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLVTDLPAIFDQFSEARQKGFLTVMDLKVRGIPLVGTYCTFMPQEIPMAAGAVVVSLCSTSDETIEEAEKDLPRNLCPL
IKSSYGFGKTDKCPYFYFSDLVVGETTCDGKKKMYEYMAEFKPVHVMQLPNSVKDDASRALWKAEMLRLQKAVEERFGHE
ISEDALRDAIALKNRERRALANFYHLGQFNPPALSGSDILKVVYGATFRFDKEALINELDAMTARIRQQWEEGQRLDPRP
RILITGCPIGGAAEKVVRAIEENGGWVVGYENCTGAKATEQCVAETGDVYDALADKYLAIGCSCVSPNDQRLKMLSQMVE
EYQVDGVVDVILQACHTYAVESLAIKRHVRQQHNIPYIAIETDYSTSDVGQLSTRVAAFIEIL
>SEQF1516_EDU87374.1 anaerobic ribonucleoside-triphosphate reductase activating protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNYHQYYPVDIVNGPGTRCTLFVSGCVHECPGCYNKSTWRVNSGQPFTKAMEDQIINDLNDTRIKRQGISLSGGDPLHPQ
NVPDILKLVQRIRAECPGKDIWVWTGYKLDELNAAQMQVVDLINVLVDGKFVQDLKDPSLIWRGSSNQVVHHLR
>SEQF1516_EDU87375.1 hypothetical protein ECH7EC4501_2744 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGFSLLFNPYYWIFVKPFNGVPGAGKKDIQEKMCAISDSYAV
>SEQF1516_EDU87376.1 D-serine/D-alanine/glycine transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMGSGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLS
NLEYKSFSDFASDLLGPWAGYFTGWTYWFCWVVTGMADVVAITAYAQFWFPDLSDWVASLAVIVLLLTLNLATVKMFGEM
EFWFAMIKIVAIVSLIVVGLVMVAMHFQSPTGVEASFAHLWNDGGWFPKGLSGFFAGFQIAVFAFVGIELVGTTAAETKD
PEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSVVPEKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSR
MLFGLAQEGVAPKAFAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILCSYLVYRKQ
RPHLHEKSIYKMPLGKLMCWVCMAFFVFVVVLLTLEDDTRQALLVTPLWFIALGLGWLFIGKKRAAELRK
>SEQF1516_EDU87377.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFLIQGIFMAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLPWALMKCKRYLYASMEVNGQRFSYGITG
GNVFFSCLVFVFFYFAILMTVSADMPLIGCVLTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSMKGVWWVTFFLPI
LMAIGMGTVFFISTKMLHANSSSSVIVSVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFKVKLDTAYCIKYAI
LAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQRKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSL
NDGRIRFRSTLTYHGMLYRMCALVVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLASISRGI
MPSLPFL
>SEQF1516_EDU87378.1 hypothetical protein ECH7EC4501_2771 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAIIDTERQFPSRITVNKNTYILTYNSNKPFALTKYCIKCLHRF
>SEQF1516_EDU87379.1 transcriptional regulator UlaR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLDESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEK
VRIAKAASQLVNPGESVVINCGSTAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSEN
SLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLFSRADQIDMLITGKNANPEILQQ
LEAQGVSILRV
>SEQF1516_EDU87380.1 hypothetical protein ECH7EC4501_2728 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKNLASVSGDKDQVNMHQENTMPSTPDIGFFFHRPKYHLACETTTGI
>SEQF1516_EDU87381.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLARL
KNIDVNDWQPHANPVVVWDIFGEKGHSVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQY
IGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKGVINILSAEKLYQMPKLYAASLL
WMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQ
HALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLIN
HSPVYGKYEDEVDRESAYEMLQKGFQASTEQQNNPPAKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAAR
QVTNQIVRGMLGSLLGGRRR
>SEQF1516_EDU87382.1 putative L-ascorbate-6-phosphate lactonase ulaG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLGCTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGH
QMQRMAGVKKLQPNLRTTPFVLDPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKER
CIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPGGSLYHSGDSHYSNYYAKHGNEH
QIDVALGSYGENPRGITDKMTSADMLRMGEALNAKVVIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGK
FTWPLDKDNFEYHYPRGFDDCFTIEPDLPFKSFL
>SEQF1516_EDU87383.1 prophage P4 integrase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALTDTKVRSAKPEEKEYSLVDGDGMSLLVKPGGSKYWRFRFRFGGKQHLMAFGVYPDVSLADARKKREEARKLVAAGID
PREHKRAVKEEQAKEIITFEKVAREWLVTNQKWSEDHANRVKKSLEDNIFPTIGTRNIAELGTRDLLIPIKAVEKSGRLE
VASRLQQRTTAIMRYAVQSGLIDYDPAQEMSGAVASSNRQHRPALELKRIPELLDKIDSYTGRPLTHCTTELTLLIFIRS
SKLHFARWSEIDFETSMWTIPLDWYCSKQRVGLVQ
>SEQF1516_EDU87384.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLSIDISELIQLGKKMLPEGVDFFLDESPIDFDPIDIELSTGKEVSIEDLDPGSGLISYHGRQVLLYIRDHSGRYDAAI
VDGEKGKRFHIAWCRTLDEMRHKNRFERYHATNRIDGLFEIDDGSGRSQDVDLRVCMNCLERLNYKGSIDKQRKREIFKS
FSLNEFFSDYSTCFRHMPKGIYDKTNSGYVENWKEISKEIREKANYVCNDCGVNLSTAKNLCHVHHKNGIKYDNHHENLL
VLCKDCHRKQPLHEGIFVTQAEMAIIQRLRSQQGLLKAESWNEIYDLTDPSVHGDINMMQHKGFQPPVPGLDLPNSEHEI
IATVEAAWPGLKIAVNLTPAEVEGWRIYTVGELVKEIQTGAFTPAKL
>SEQF1516_EDU87385.1 valyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTD
HAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRL
YKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDP
RYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNE
SDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENG
DIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEEEVRKENNLGADVALRQDEDVLDTWFSSA
LWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKG
NVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRN
FCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELT
KPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWL
KQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIIDGAELLIPMA
GLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>SEQF1516_EDU87386.1 outer membrane usher protein fimD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHIRKHRLAGFFVRLFVACAFAVQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVT
FNTGDSEQGIVPCLTRAQLASMGLNTASVAGMNLLADDACVPLTTMVQDATAHLDVGQQRLNLTIPQAFMSNRARGYIPP
ELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDRSSGSKNKWQHINTWLERDII
PLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDI
YAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQ
LADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYS
RMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRSSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINW
TLSYSLTKNAWQKGRDQMLARNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGY
AGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQT
GVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMV
TSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR
>SEQF1516_EDU87387.1 protein PmbA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTTGISVSTRYGEVENVEFNSDGALGITVYHQNRKGSAS
STDLSPQAIARTVQAALDIARYTSPDPCAGVADKELLAFDAPDLDLFHPAEVSPDEAIELAARAEQAALQADKRITNTEG
GSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMSDLQTPEWVGADCARRTLSRLSPRKLS
TMKAPVIFANEVATGLFGHLVGAIAGGSVYRKSTFLLDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDIIK
DGILTQWLLTSYSARKLGLKSTGHAGGIHNWRIAGQGLSFEQMLKEMGTGLVVTELMGQGVSAITGDYSRGAAGFWVENG
EIQYPVSEITIAGNLKDMWRNIVTVGNDIETRSNIQCGSVLLPEMKIAGQ
>SEQF1516_EDU87388.1 protein FimH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVNLAPAVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQ
RGSAYGGVLSNFSGTVKYSGSSYPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTKNYNS
DDFQFVWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYLSGTTADAGNSIFTNTASFSPAQ
GVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTANYARTGGQVTAGNVQSIIGVTFVYQ
>SEQF1516_EDU87389.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLWKKISLGVVIVILLLLGSVAFLVGTTSGLHLVFKAADRWVPGLDIGKVTGGWRDLTLSDVRYEQPGVAVKAGNLHLA
VGLECLWNSSVCINDLALKDIQVNIDSKKMPPSEQVEEEEDSGPLDLSTPYPITLTRVALDNVNIKIDDTTVSVMDFTSG
LNWQEKTLTLKPTSLKGLLIALPKVAEVAQEEVVEPKIENPQPEEKPLGETLKDLFSRPVLPEMTDVHLPLNLNIEEFKG
EQLRVTGDTDITVRTMLLKVSSIDGNTKLDALDIDSNQGILNASGTAQLSDNWPVDITLNSTLNVEPLKGEKVKLKVGGA
LREQLEIGVNLSGPVDMDLRAQTRLAEAGLPLNVEVNSKQIYWPFTGEKQYQADDLKLKLTGKMTDYTLSMRTAVKGLEI
PPATITLDAKGNEQQVNLDKLTVAALEGKTELKALLDWQQAISWRGELTLNGINTAKEIPEWPSKLNGLIKTRGSLYGGT
WQMEVPELKLTGNVKQNKVNVDGTLKGNSYMQWMIPGLHLELGPNSAEVKGELGVKDLNLDATINAPGLDNALPGLGGTA
KGLVKVRGTVEAPQLLADITARGLRWQELTVAQVRVEGDIKSTDQIAGKLDVRVEQISQPDVNINLVTLNAKGSEKQHEL
QLRIQGEPVSGQLNLAGSFDRKEERWKGTLSNTRFQTLVGPWSLTRDIALDYRNKEQKISIGPHCWLNPNAELCVPQTID
AGAEGRAVVNLNRFDLAMLKPFMPETTQASGIFTGKADVAWDTTEEGLPQGSITLSGRNVQVTQTVNDAALPVAFQTLNL
TAELRNNRAELGWTIRLTNNGQFDGQVQVTDPQGRRNLGGNVNIRNFNLAMINPIFTRGEKAAGMVSANLRLGGDVQSPQ
LFGQLQVTGVDIDGNFMPFDMQPSQLAVNFNGMRSTLAGTVRTQQGEIYLNGDADWSQIENWRARVTAKGSKVRITVPPM
VRMDVSPDVVFEATPNLFTLDGRVDVPWARIVVHDLPESAVGVSSDVVMLNDNLQPEEPKTASIPINSNLIVHVGNNVRI
DAFGLKARLTGDLNVVQDKQGLGLNGQINIPEGRFHAYGQDLIVRKGELLFSGPPDQPYLNIEAIRNPDATEDDVIAGVR
VTGLADEPKAEIFSDPAMSQQAALSYLLRGQGLESDQSDSAAMTSMLIGLGVAQSGQIVGKIGETFGVSNLALDTQGVGD
SSQVVVSGYVLPGLQVKYGVGIFDSIATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF
>SEQF1516_EDU87390.1 putative permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGL
GMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLG
VVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFY
VLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>SEQF1516_EDU87391.1 mannonate dehydratase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEEILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQ
WIANYQQTLRNLAQCGIRTVCYNFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAE
RFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKAIIPVAEEVGVRMAVHPDDPPRP
ILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYGVRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGD
VDMYEVVKAIVEEEHRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFFSH
>SEQF1516_EDU87392.1 type I restriction-modification system, M subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEYNMSISSVIKSLQDIMRKDAGVDGDAQRLGQLSWLLFLKIFDAQEEALELEQDNYQYPIPQRYLWRSWAANAQGITGD
SLLEFVNDDLFPALKNLTAPIDKNPRGYVVKQAFSDAYNYMKNGTLLRQVINKLNEIDFTSASERHLFGDIYEQILKDLQ
SAGNAGEFYTPRAVTRFMVDRVDPKLGESIMDPACGTGGFLACAFDHVKNKYVKSVADHQTLQQQIHGVEKKQLPHLLAT
TNMLLHGIEVPVQIRHDNTLNKPLSSRDEQLDVIVTNPPFGGTEEDGIEKNFPAEMQTRETADLFLQLIVEVLAKNGRAA
VVLPDGTLFGEGVKTKIKKLLTEECNLHTIVRLPNGVFNPYTGIKTNLLFFTKGQPTKEIWFYEHPYPAGVKNYSKTKPM
KFEEFQAEIDWWGNEADGFASRVENEQAWKVSIDDVIARNFNLDIKNPHQAETVSHDPAELLAQYAKQQAEIQTLRNQLR
DILGAALSGKEVN
>SEQF1516_EDU87393.1 type 1 fimbriae regulatory protein FimE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKRRYLTGKEVQAMMQAVCYGATGARDYCLILLAYRHGMRISELLDLHYQDLDLNEGRINIRRLKNGFSTVHPLRFDER
EAVERWTLERANWKGADRTDAIFISRRGSRLSRQQAYRIIRDAGIEAGTVTQTHPHMLRHACGYELAERGADTRLIQDYL
GHRNIRHTVRYTASNAARFAGLWERNNLINEKLKREEV
>SEQF1516_EDU87394.1 ornithine carbamoyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLTGKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPS
GSQIGHKESIKDTARVLGRMYDGIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKPFNEMTLV
YAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTEDVAKGVEGADFIYTDVWVSMGEA
KEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLPAFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENR
MHTIKAVMVATLSK
>SEQF1516_EDU87395.1 ribonuclease R [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVELHIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPE
RLDLVKGTVIGHRDGYGFLRVEGRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEA
GVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNMGTGMAVDIALRTHEIPYIWPQA
VEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDARDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRG
TSVYFPSQVIPMLPEVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQGDQDLREQY
APLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQTQRNDAHKLIEECMILANISAARFVEKAKEP
ALFRIHDKPSTEAITSFRSVLAELGLELPGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLAL
QSYAHFTSPIRRYPDLMLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRADEATRDVSDWLKCDFML
DQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYYRFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKI
DFSLISSERAPRNVGKTAREKAKKGDAGKKGGKRRQVGKKVNFEPDSAFRGEKKTKPKAAKKDARKAKKPSAKTQKIAAA
TKAKRAAKKKVAE
>SEQF1516_EDU87396.1 SdiA-regulated protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKRITFIVFLCAIVAASLFFVQSCVRKSQHVAGFQNYQATIDGKEITGVTKNISSLTWSAQSNTLFSTINKPATIVEMT
TEGDLIRTIPLDFVKDLETIEYIGDNKFVISDERDYAIYVISLNADSEVSILKKIKIPLQETPTNCGFEGLAYSSQDHTF
WFFKEKNPIEVYKVTGLLRSDELHISKDKTLQRQFTLDDVSGAEFNPQKNTLLVLSHESRALQEVTVRGDVIGEMSLTKG
KYGLSHNIKQAEGIAMDDSGNIYIVGEPNLFYRFTSTKSR
>SEQF1516_EDU87397.1 HflK protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAWNQPGNNGQDRDPWGSSKPGGNSEGNGNKGGRDQGPPDLDDIFRKLSKKLGGLGGGKGTGSGGGSSSQGPRPQLGGRV
VTIAAAAIVIIWAASGFYTIKEAERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNVEAVRELAASGVMLTSDENVVRVE
MNVQYRVTNPEKYLYSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQRELEETIRPYDMGITLLDVNFQA
ARPPEEVKAAFDDAIAARENEQQYIREAEAYTNEVQPRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYKAAPE
ITRERLYIETMEKVLGNTRKVLVNDKGGNLMVLPLDQMLKGGNAPAAKSDNGASNLLRLPPASSSTTSGASNTSSTSQGD
IMDQRRANAQRNDYQRQGE
>SEQF1516_EDU87398.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTQVRKNVMDMFIDGARRGFTIATTNLLPNVVMAFVIIQALKITGLLDWVGHICEPVMALWGLPGEAATVLLAALMSMG
GAVGVAASLATAGALTGHDVTVLLPAMYLMGNPVQNVGRCLGTAEVNAKYYPHIITVCVINALLSIWVMQLIV
>SEQF1516_EDU87399.1 resolvase TnpR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFPAGHPIFITVFWQGPDEEMTMAIFGYGRVSTSQQDTENQRMELEQAGWTFDFWFSDVVSGKVPAVQRKAFFEMLSKI
RDGETLVVAKLDRLGRDAIDVLQTVRTLADRNIKVIVHQLGTTDLTSAAGKLLLSMLAAVAEMERDLLIERTNAGLLRAK
AEGRKLGRPAKIAPEARGAILDKRAAGVSVSALAREYGVSRATLAALLNKGY
>SEQF1516_EDU87400.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGFFQRLFGKDNKPAIARGPLGLHLNSGFTLDTLAFRLLEDELLIALPGEEFTVVAVSHIDLGGGSQIFRYYTSGDEFL
QINTTGGEDIDDIDDIKLFVYEESYGISKENHWREAINAKTMGAMTLNWQEKRWQRFFNSEEPGNIEPVYMLEKVENQNH
AKWEVHNFTMGYQRQVTEDTYEYLLLNGEESFNDLGEPEWLFSRALGVDIPLTSLHIIG
>SEQF1516_EDU87401.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRSGESRQQITDYPEMRFSLARHMRKMSGRLKKDSDACAFIF
>SEQF1516_EDU87402.1 NmrA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIAITGATGQLGQYVIESLMKTVPASQIVAIVRNPAKAQALTAQGITVRQADYGDEAALTSALQGVEKLLLISSSEVGQR
APQHRNVINAAKTAGVKFIAYTSLLHADKSPLGLADEHIETEKMLADSGIVYTLLRNGWYTENYLASAPAALEHGVFIGA
AGDGKIASATRADYAAAAARVISEAGHEGKVYELAGDSAWTLTQLAAELTKQSGKQVTYQNLSEADFAAALKSVGLPDGL
ADMLADSDVGASKGGLFDDSKTLSKLIGHPTTTLAESVSHLFNVNN
>SEQF1516_EDU87403.1 putative permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLY
TESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLF
IESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVA
LDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNG
GKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>SEQF1516_EDU87404.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFGNLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMSYEEFFRERQNARYGGDGKGGMRCC
>SEQF1516_EDU87405.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIFQRYNPLQVAKYVKILFRGRLYIKDVGAFEFDKGKILIPKVKDKLHLSVMSEVNRQVMRLQTEMA
>SEQF1516_EDU87406.1 3'(2'),5'-bisphosphate nucleotidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDQVCQLARNAGDAIMQVYDGAKPMDVVSKADNSPVTAADIAAHTVIMDGLRTLTPDIPVLSEEDPPGWEVRQHWQRYW
LVDPLDGTKEFIKRNGEFTVNIALIDHGKPILGVVYAPVMNVMYSAAEGKAWKEECGVRKQIQVRDARPPLVVISRSHAD
AELKEYLQQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTNIWDTAAGHAVAAAAGAHVHDWQGKPLDYTPRESFLNPG
FRVSIY
>SEQF1516_EDU87407.1 tRNA delta(2)-isopentenylpyrophosphate transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSALIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYS
AADFRRDALAEMADITAAGRIPLLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEIDPVAAARI
HPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRFHQMLASGFEAEVRALFARGDLH
TDLPSIRCVGYRQMWSYLGGEISYDEMVYRGVCATRQLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG
>SEQF1516_EDU87408.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSMPLSNVLQSQIITDNHFLHHPKVESELTRKYERARLDTENIYLLPLARGNNHNYDGKSVVEIRKLDISKESWPFNYVT
EACRESDGITTTGRMLYRNLKITSALDEIYGGICKKAHAATELAEGLRLNLFMKSPFDPVEDYTVHEITLGPGCNVPGYA
GTTIGYISTLPASQAKRWTNEQPRIDIYIDQIITVSGVANSSGFALAALLNANIELGNDPIIGIEAYPGTAEIHAKMGYK
VIPGDEDAPLKRMTLQPSSLPELFELKNGEWNYIGK
>SEQF1516_EDU87409.1 DEAD/DEAH box helicase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDVQQLHYAPLLNQLHQRAVRSVVSQLALRSKSLTHYLESQYFQPPGQEGSLLADPVFESTFGWMPADETMEDLRDKLIS
SPLVDALSKAPVPFRHQLTAWRTILEDKKSLLVSSGTGSGKTECFMVPVLEDLIRQQKSTRQSLTGTQAIFLYPLNALIN
SQQERLREWTRGFKGKIRFALYNGETRHTKYEIQEDQLKVPEQALSREAIYEAPPSIMVTNTTMLEYMLIRRKDAPIIEK
SQGMLKYIVLDEAHSYIGSQAAELALLLRRVMQAFNVGPGTDKPVQIIATSATIGEDSPEGNKELAKFVADLAGVTERDV
KVVRGYRQIPRVSESLIRHEYPTSLTSLKSLSPQDLYQQLCHYRVAQQLRQALTHPGRQAVRLSELLNVARRTWPDINHR
ELLQLLDLMARSREGELAFTPLRMHGFIRTLAGLWACSNKQCSHKAHELNQSDWPFGQVWFEQRQYCDCGAPVFEVLRCS
GCGSAYLSAKEEMRGDGTNWLVAQPAAAEVDEFALDVDVYSEDEDNDELDNNSQFDRLIASDGEKYIISLEETTAGKIDS
EAQKHYEINLLRPESRGEGRNNSFACVCCGDTQRKNNPLFRPLRLGAPFFLNEIIPTLLEFSPLPQTREEQLGPFNGRRL
LTFTDSRQGTARISARLQQDADKATLRALCYQELANITEPSAKLSPAHCALLEKVISQFSVLPLKNSIDALKKAMAANEE
LSPTDIQALKIIEPMVSSLSTEHAEAMQILQANSGNQQKKTMSWQTLSEQLVGSVDLADRMRGSFKELSGLDLTKQQFAD
FCLYSEFGRRPKNAWTLESLGLVAIHYPFIDKVTTCPQDWKTLLPDPDKQLAEWRNLLKITLDFFIRENSAVFYENEQYP
RWMGARFPVKMLQGPDKKNKGQKRDQLWPQIRDRHYNRVIKLLIAVFPAIQPEQAHWKSLVNHLMIEVWDAIRPCLRQFE
SGYQLDIKQQAEFYSPKQVWRCPYTRRALDVTLLGYSPYLPGSKEIAPEKAVLIEMPELPVRHWRLSGGGEIAREERLEW
LESNALIQHAREEGLWSTRSDRLALKDSWYRLEEHSAQRTPEQNQFNEKQFKSGKVNVLNCSTTMEMGVDIGGMSLVAMN
NVPPAPANYLQRAGRAGRRGESASAAITLCKNTAHGMEVFKDPLWAFNTTASAPRVRFGSSSIVQRHVNALVLGLFLRAE
VPDATKLSCKWFFEGDESQCLRFLHWLNHQADQLADKLKRLTQGTVLMSLTATQLLTRTQAMMQQVDIRWRSQLAILLEN
IEALKADNSAWEETPAGKAIAYQLRDYRGAYLFSKLISEAFLPGHGFPVGVVNFNYLTADELEKRRAIKATQADPNEGGE
SFSRRIEKLPSRDLPTALREYAPGADVVLGGKVYRSSGIMLGKVLASGQELSGDHHIPWFWHCRKCGAGATSTTHPVECS
HCKADIQQLDVKRYLQPVGFATDIRYQAHNDVSMPAQLPWKDPRVLVPSSVWVSLPDAGLGRYRFSHSGELFHFSEGEFG
HGYAICLSCGRAESQTQPQRTPENLKNPERENTHYLLRGGSNDRQGSNKLCHGHVHKDLWLGYSSRTDMVELQLNDDNGL
LIRDEVAARSLAVALREGLAHKLGIENTELGVTTQQARDINGYTGYSIFIYDNNAGGAGYAVQLIDHWADVFNYARKLLD
CSCDKFCHHCLLSYDSQHYVNRLDRHHALTLLTNVRLQRLNLAPEYQYFGDGSRVETNPLSLRIAQCLNSEIYDSCSLVL
AGPQEQWDFAQWPLFKELLQFASSGGNVELLVATPLANLTDSSRHQLSALAAMPGGRLQVKSIATAQLMQGKGRWLAQVT
REGQSQQWAADDSATVAPGELWGQSASSPVVTLKGTSGKTFSGQTLSAEDLLPALPTGAVRINLCEQLDGPLEGFGSRFW
SLVTQQHAGWKQAFTRHKEITHVEYSDRYLNSPFTARLLGEILTELVEQGMAERASLTVCVKKLDYNSRQHDALYNAWLN
EEDRQQVVTTLLEEGYLGPAWPGAISWLTGDNQSTEHGRELTVTFSDGSQHYVLLDMGLSYWRCIEDTFFDFALRVPQQV
ERLANTRARAVAPGNDLRSYIIAG
>SEQF1516_EDU87410.1 type-1 fimbrial protein homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKTLAIVVLSALSLSSTAALAAATTVNGGTVHFKGEVVNAACAVDAGSVDQTVQLGQVRTASLAQDGATSSAVGFNIQ
LNDCDTNVASKAAVAFLGTAIDAGHTNVLALQSSAAGSATNVGVQILDRTGAALTLDGATFSEQTTLNNGTNTIPFQARY
YAIGEATPGAANADATFKVQYQ
>SEQF1516_EDU87411.1 hypothetical protein ECH7EC4501_2773 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVGQQGKQRFFLPFGYPQDLRHEQKIYIYQEPLLADDVSKQNPDIMGNGWA
>SEQF1516_EDU87412.1 hypothetical protein ECH7EC4501_2814 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGGNAHKLRMIFKQKLLKSELGQLPWKISPGEQLFIQR
>SEQF1516_EDU87413.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPRIRHNNFIGAVELFVKSSYTKTHSNNFFNNIHHAFKKKDWISNYDSLLTLREFFRCATQIDKSSYQVLSSKNETVNA
MDKFLISFSLKDNGAEYTMTLRGSGFEYEEIPITINEYNSFMDFKNREFPLEQNRRLYAWDILQKKQSDIPKRIKGYIHQ
AIGDVSLGYALLDDIVSKLKRGKFELQGPGGGIKQCDGWYIYEKIIDDNFAIVIESLGFALKIYGGDERFRNGSSVVLED
EDYSLIYNFLVNAGCQQVELAEQVDAIVSANLAADSDITKEKICEKYKSTIEAFKKEQLALPVLVRRKNSET
>SEQF1516_EDU87414.1 putative sugar ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPQSLPDTTPPKRRFRWPTGMPQLAALLLVLLVDSLVAPHFWQVVLQDGRLFGSPIDILNRAAPVALLAIGMTLVIATGG
IDLSVGAVMAIAGATTAAMTVAGFSLPIVLLSALGTGILAGLWNGILVAILKIQPFVATLILMVAGRGVAQLITSGQIIT
FNSPDLSWFGSGSLLFLPTPVIIAVLTLILFWLLTRKTALGMFIEAVGINIRAAKNAGVNTRIIVMLTYVLSGLCAAIAG
IIVAADIRGADANNAGLWLELDAILAVVIGGGSLMGGRFNLLLSVVGALIIQGMNTGILLSGFPPEMNQVVKAVVVLCVL
IVQSQRFISLIKGVRSRDKT
>SEQF1516_EDU87415.1 hypothetical protein ECH7EC4501_2763 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLSGGYRSKSSLSPGNAGHSGVLSVSMLFLLIFQPANSLKNLHNAVAPVIRTLCFLL
>SEQF1516_EDU87416.1 hypothetical protein ECH7EC4501_2776 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLALIRKAGTRLPISCDKTIIHALRLAELIIFSYNGGNETLF
>SEQF1516_EDU87417.1 IS1203 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU87418.1 IS605 family transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRLQAFKFQLRPGGQQEREMRRFAGACRFVFNRALALQNENHEAGNKYIPYGKMASWLVEWKNATETQWLKDAPSQPLQ
QSLKDLERAYKNFFRKRAAFPRFKKRGQNDAFRYPQGVKLDQENSRIFLPKLGWMRYRNSRQVTGVVKNVTASQSCGKWY
ISIQTENEVSTPVHPSALMVGLDAGVAKLATLSDGTVFGPVNSFQKNQKTLARLQRQLSRKVKFSNNWQKQKRKIQRLHS
CIANICRDYLHKVTTTVSKNHAMIVIEDLKVSNMSKSAAGTVSQPGRNVRAKSGLNRSILDQGWYEMRRQLEYKQLWRGG
QVLAVPPAYTSQRCACCGHTAKENRLSQSKFRCQACGYTANADVNGARNILAAGHAVLACGEMVQSGRPLKQEPTEMIQA
TA
>SEQF1516_EDU87419.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFHENKAKTPFIRLVQLWQAVRRWRRQMQARRVLQQMSDERLRDIGLRREDVE
>SEQF1516_EDU87420.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSTIWLALALVLVLEGLGPMLYPKAWKKMISAMTNLPDNILRRFGGGLVVAGVVVYYMLRKTIG
>SEQF1516_EDU87421.1 hypothetical protein ECH7EC4501_2847 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLEPGKFLELKNLISHVGMGKMQVCFWLCVFCIGEKLRCVEKVLRRIELQKIHKPSDNDIGK
>SEQF1516_EDU87422.1 ATP-dependent DNA helicase, UvrD/REP family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVQTPKVALSDGFLGAFARIPKAQQKKVQEFISKFRQDPTSNGLNYEKIHDARSKNVHSVRIDQTYRGIVLKPEQGALY
MLMWVDKHDEAYDWARRHDCSIHPVTGAIQVIDISYIKPAAETVVDKPKLFAAYSAEQILALGVPPVFIDQVMALTDEAG
LNQLESIMPAEAWEPLHWLAEGLDYQEVLEEFNDHRDEPVDTNDFMEAIERSKRRFHVVENEQELLQMLNAPLEKWRVFL
HPSQRKLVESPANGPVRVLGGAGTGKTVVAMHRARWLSQRLADKPGKKVLFTTFTRNLAADIRANLQRLCTREEMARIDV
VNIDAWMSDQLKRHGYDFRVVYDSDEGRRKCWNYALQQAPAELGLPDNFYAEEWQRVVQPNAVYTREEYLKVSRVGRGTA
LSRIQRAKIWPVFEEFRAQMARAKLREMGDAMHEAIVLFKEKQVQLPYSSIVVDEAQDIGAPAFTLIRSLVPESPNDLFI
VGDGHQRIYRNKVVLGQCGINVRGRRSKKLKINYRTTEETRQFAVGLLTGVKVDNLDGEADTSNDYLSLLHGEKPMITHA
ADFKEEAATLVKQIQALLANQVRSQDICITARTKHACDRYASALNDAGIETFNLGNDSGDSDARPGVRVATMHRIKGLEF
QYVFLVGINEGVVPEIKALASDDPVEQRDALFNERALLHVAATRAVKGLFVSSSGVPSPLLVAD
>SEQF1516_EDU87423.1 fructose-1,6-bisphosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGAENVQGEVQQKLDLFANEKLKAALKAR
DIVAGIASEEEDEIVVFEGCEHAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVV
YGSSTMLVYSTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVKKYIKFCQEEDKSTNRPYTSRYI
GSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYECNPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVE
DVERFICEFPDA
>SEQF1516_EDU87424.1 aspartate carbamoyltransferase, regulatory subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITIGLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQ
ATVNRIDNYEVVGKSRPSLPERIDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN
>SEQF1516_EDU87425.1 oxidoreductase, short chain dehydrogenase/reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAERLAQETGATAVFTDSADRDAVIDVVRKSGALDILV
VNAGIGVFGDALELNADDIDRLFKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGL
ARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSFMAIKRHGQPEEVAGMVAWLAGPEASFVTGAMHTIDGAFGA
>SEQF1516_EDU87426.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARKRKSRNNSKIGHGAISRIGRPNNPFEPRRNRYAQKYLTLALMGGAAFFVLKGCGDSGDVDNDGDGTFYSTVQDCIDD
GNNADICARGWNNAKAAFYADVPKNMTQQNCQSKYENCYYDNVEQSWIPVVSGFLLSRVIRKDRDEPFVYNSGGSSFASR
PVWRNTSGDYSWRSGSGKKESYSSGGFTTKKASTVSRGGYGRSSSARGHWGG
>SEQF1516_EDU87427.1 hypothetical protein ECH7EC4501_2841 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKREWLWKMSINTVVPGVQGKPHMLLNVRSAQNDAPITSGCFT
>SEQF1516_EDU87428.1 hypothetical protein ECH7EC4501_2786 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEEDQKQDEEYRQLAFERLPHQISYDYHFKYARKNSSFAGF
>SEQF1516_EDU87429.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNRDFDHLSTLLHLFFEREDICQKLNIIDQNNITGWEVWFQVEFANMLCSTDHEWWREQALSCDMRKKPERPTLRTDFL
LRKKGWAQDSYIALEIKQNRDATSCVKNMIADLEKSAKIKRSELDLRSFWTLGITPMIDRERLDSLIDCYLDEKFYLTKS
RKKHVLLKEINNTPYCYIVI
>SEQF1516_EDU87430.1 hypothetical protein ECH7EC4501_2866 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVLAPHPHRAKYLDISSVNMGKVQLKINENKMKISVKYKFW
>SEQF1516_EDU87431.1 kelch repeat protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKTITALAILMASFAANASVLPETPVPFKSGTGAIDNDTVYIGLGSAGTAWYKLETQAKDKKWTALAAFPGGPRDQATS
AFIDGNLYVFGGIGKNSEGLTQVFNDVHKYNPKTNSWVKLISHAPMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNE
AGKDSTAVDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGESPWYGTAGAAVVNKGDKTWLINGEAKPGLRTDAVFE
LDFTGNNLKWNRLAPVSSPDGVAGGFAGISNDSLIFAGGAGFKGSRENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSG
ELSQGRAYGVSLPWNNSLLIIGGETAGGKAVTDSVLISVKDNKVTVQN
>SEQF1516_EDU87432.1 putative inner membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHILDSLLAFSAYFFIGVAMVIIFLFIYSKITPHNEWQLIKNNNTAASLAFSGTLLGYVIPLSSAAINAVSIPDYFAWGG
IALVIQLLVFAGVRLYMPALSEKIINHNTAAGMFMGTAALAGGIFNAACMTW
>SEQF1516_EDU87433.1 L-ribulose-5-phosphate 4-epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKLKQQVFEANMDLPRYGLVTFTWGNVSAIDRERGLVVIKPSGVAYETMKADDMVVVDMSGKVVEGEYRPSSDTATHLE
LYRRYPSLGGIVHTHSTHATAWAQAGLAIPALGTTHADYFFGDIPCTRGLSEEEVQGEYELNTGKVIIETLGNAEPLHTP
GIVVYQHGPFAWGKDAHDAVHNAVVMEEVAKMAWIARSINPQLNHIDSFLMNKHFMRKHGPNAYYGQK
>SEQF1516_EDU87434.1 ascorbate-specific phosphotransferase enzyme IIB component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEYKSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLS
PADFGPKLLEVIKEHFPQDVK
>SEQF1516_EDU87435.1 type II restriction enzyme, methylase subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALVGINNENEFYSNHYLGEVFTSDIRDVLEPWIAQENAAREAERAAREQGKDVEPGYRAPWNQFNSLATEFFRKLAEHE
KQRQIPQRLADQRNRWQPLLKALGYEITPQIQMLDDDTPLPVLARYNSTDGSPWLWIVEAHDQEEGTLDPLALSLLTAQF
PADTDKHKHDSLRKKANGEYRSWQDLLSTAVFTQNEPPRFVLLLGNRQLLLLDRTKWAQNRLLRFDFEEILSRRETDTLK
ATAVLLHKDSLLPGSGAPYLDSLDDNSHKHAFGVSEDLKYALRESIELLGNEAMHYLIDRGLANYTGNRAVDPDELSREC
LRYMYRLLFLFYIEARPELGYAPMTAKTYLQGYSLETLRDLEMIPLTSEEDRNGRYFHDSLNMLFKLVREGYNGGVKMQS
DLESGDRITIHSHQFSVPRLESHLFDANNTRILNRVVFRNETLQQIIQAMSLSRPAKGRFNRRGRISYRQLGINQLGAVY
EALLSYRGFFASEDLYEVKKAGEEFNELETGYFVSKDEISKYHEDEKVYEKDGSLRIHRKGSFIYRMAGRDREKSASYYT
PEVLTRSLVKYALKELFKEQIDPISDPHAKADAILNLTVCEPAMGSAAFLNEAINQLAEAYLFHKQQAEGRRIPQDRYTQ
ELQRVKMYIADNNVFGVDLNPVAVELAEVSLWLNAISGDAFVPWFGYQLHCGNSLVGARRQVFNKSELTYKKAKDPSWLN
SEPVELAMNTPREETQIFHFLLPDGGMANYSDKTVKQRYPDDFKALDSWRKEFIKSFAGHEIADVQRISEKVEALWNTYR
QQLKAERLKTADSYPVWPAENSEQTRSSLSSKDETFSGRLEDNSAYQKLRWVMDYWCALWFWPIDKADELPDRGTWLFEI
ETLLDGIVITEKVTEVAEHTTGDLFAEEGLLREESSLFSVAGRLKTEVLFRHLPRLAIVDALRKQHRFFHWDLEFCDLFA
ERGGFDLMLGNPPWLKVEWQEAGVLGDYEPEFVLRKLSASKLATLRIDTFNQIPALEAAWRSEYEGCEGMQNFLNAQQNY
PVLRGVQTNLYKCFLPQAWRLGAQKGVAGFLHPEGIYDDPKGGQLRAAVYPRLRAHFQFQNELNLFVEVDHHAKFSSNIY
SASPSTVGFEHISNLYAPQTIDACFEHSGSGDIPGLKDEIESEGKLKVVWNTSGHRSRLISIATHELELFARLYDSEGTP
AWQARLPALHAKQLVAVLEKFANQPNRLGDLQGQYFSTVMFDETYAQRDGTILRQTQFPQDSSQWVLSGPHFFVGTPFYK
TPRENCTLNSDYDCLDLLTLPDDYLPRTNYIPACDAQEYAKRTPCVTWTELAEDEPKKVTDYYRLAIRAMLAQSGERTLI
SAIYPPEISHMNAVRSYCYSSQNLLLEHSGMCFSLPFDFICKSTGKANLHQMLDGFSYVLFNPRQKALLYCLVLSLNSVN
DVYAGLWQSCYTPDFNTQRWSRDLPQLPQDFFAKLTPEWQRNCALRSDYSRRQALVEIDVLVAQALGLTLEELLTIYRVQ
FPVMRQYEADTWYDQNGRIIFTPSKGLVGVGLPRTARKADLKNGFVFNVDSPEWTGGDCTDQAIGWDDVKHLKTGTVSVT
FDDYTRSDEGERRTVTWQAPFIKPDREDDYKVAWAFFAQDKESA
>SEQF1516_EDU87436.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIENESGYLITYFRRIYQALRGQSSQYPAAKIAQELGDTIPVTMQNELVYEIAGEFCETLCRLLSEHPPHSSDPVSALRK
LSPDWHLQLPLVLPEANAAEIVRRLLSQSSEIRSASSLQVERIWVDVDDSWYCDARFRFPATMRTEQLTSLFECHIQPEQ
TRLIISGKWKNGGARLAMLSRYEQQDWRVELLPIAMQKLSGADAMAEISLSLHEGPILLGHTIPKGGYELTEELPWVFEA
MNESESQLKLVGMGSVSSRLNALFISLPKNSHLDISGEGEFDIPRLLKNSERSLTKISGVFSVVLHDGAVCTIRTQQLYD
SAIEYYIKSTEVELVKSDYPVHRAWPKIGWKKDLQYGIVPEKELFWRSIRSGNNAWYSVASEMPKGQIEVRRIVNDEVLF
SGKVVVLPADFDINIIPESAQQGIIMLSGITDTRIDKYSNNEKVTLKSDYSQNECAIYYNSSLMLENTVDLRVSWKDGSN
LKLLLPKPVSGGRFVTNDGSVHFDGVASIAHLHGIDAELLTISCAGRGYLNIELLDENPVAEKFRYLHADLPLLSGRNDK
LQQISLYENYNLLNAMLACAWNSNSTLCVDFYSDRFGKDKATLNIKRYDGSFIEHDQGLLVDIKNSVVFPANRIDELVVD
AISLKNPGLHISLLKKDEFAYDLSALNVQDSPWLIVGKLDGTARIAPVIKWMLPVLQTNDLLLNALCEADPEQRKKNFNE
LIFEIDNNPLQNYCCLLTEYIKKYKMNNGLSLLDLDLFRGISSNYRVVVQLLISSCLSGDSDTIYDIQEELPFSWGWIPV
SIWKDVFQKCWTYLEKQINDKTLALHILQPFIAFMNHRAHIDRRLAPIANMLLTYSESLPTGCDVLPTVSREQFNEAKQM
LLRNPDSFGRISIFPKELWSSAITPELKSVFNKLWIEDKYHSRLEKRFNLMLVAALLTQKDNNLIHQLSALFEFHYQQAP
QQLGVIYQYYFEQAGVCH
>SEQF1516_EDU87437.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEFLFLFHSTVGVIQTRKALQAAGMTFRVSDIPRDLRGGCGLCIWLTCPPGEEIQWVIPGQTEAIYCQQGSDWQCVVHY
DAEASTRQ
>SEQF1516_EDU87438.1 YjgA protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGAEIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRR
QLQLIGKMLRQRDVEPIRQALDKLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKE
GNKPPKSARQIFQYLRELAENEG
>SEQF1516_EDU87439.1 putative endoribonuclease L-PSP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQTFYRCNKGEIMSKTIATENAPAAIGPYVQGVDLGNMIITSGQIPVNPKTGEVPADVAAQARQSLDNVKAIVEAAGLK
VGDIVKTTVFVKDLNDFATVNATYEAFFTEHNATFPARSCVEVARLPKDVKIEIEAIAVRR
>SEQF1516_EDU87440.1 opacity-associated family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPGRFELKPTLEKVWHAPDNFRFMDPLPPMHRRGIIIAAIVLVVGFLLPSDDTPNAPVVTREAQLDIQSQSQPPTEEQLR
AQLVTPQNYPDQVAPVAPEPIQEGQPEEQPKTTQTQPFQPDSGIDNQWRSYRVEPGKTMAQLFRDHGLPATDVYAMAQVE
GAGKPLSNLQNGQMVKIRQNASGVVTGLTIDTGNNQQVLFTRQPDGSFIRAR
>SEQF1516_EDU87441.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKTRLSKPGFSAKSVLTIMLIAASSASYAAESIDQLATRIGMDHFREAIKKGERSAFKTLPAKGYKNGLTGLLIKTNTY
VNPEYSFADCDTDTVIISVQEHKTLPGCRISLKLATKDADGSYHDNGIRVEYGIAIGSKKFIANNSAWAQHAISGDKVLE
GALHPDKTNNNKDQMNNNKDQMCMGMAQFTANVTEGRNSGMTKREYYQRLDNMNGKADVTQQMITLYKTFVDYVYEHPKQ
DAKISGTYIYTNCMNNF
>SEQF1516_EDU87442.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRAFDSAKSMTAVLDAFYASADWRSGPREDIIGSIENCIKTVISLPSESVKGLRMQS
>SEQF1516_EDU87443.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAQLFEQLFQSIDSTLITNIFIWAVIFVFLSAWWCDKKNIHSKFREYAPTLMGALGILGTFIGIIIGLLNFNTESIDTS
IPVLLGGLKTAFITSIVGMFFAILFNGMDAFFFANKRSALAENNPESVTPEHIYHELKEQNQTLTKLVSGINGDSEGSLI
AQIKLLRTEISDSSQAQLANHTHFSNKLWEQLEQFADLMAKGATEQIIDALRQVIIDFNQNLTEQFGENFKALDASVKKL
VEWQGNYKTQIEQMSEQYQQSVESLVETKTAVAGIWEECKEIPLAMSELREVLQVNQHQISELSRHLETFVAIRDKATTV
LPEIQNKMAEVGELLKSGAANVSASLEQTSQQILLNADSMRVALDEGTEGFRQSVTQTQQAFASMAHDVSNSSETLTSTL
GETITEMKQSGEEFLKSLESHSKELHRNMEQNTTNVIDMFSKTGEKINHQLSSNADNMFDSIQTSFDKASAGLTSQVRES
IEKFALSINEQLHAFEQATEREMNREMQSLGNALLSISKGFVGNYEKLIKDYQIVMGQLQALISANKHRG
>SEQF1516_EDU87444.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMRQSLQAVLPEISGNKTSLLRKSVCSDLLTLFNSPHSTLPSLLVSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRI
AALQVNLKEAYCHTLAISLEIMLYHDDEPLTFDLVWDNGGWRSATLENVS
>SEQF1516_EDU87445.1 N-acetylneuraminic acid porin NanC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESNTWNTIHDNKKENAALNDVQVEVNYAIKLDDQWTVRPGMLTHFSSNGTRYGPYVKLSWDATKDLNFGIRYRYDWKAY
RQQDLSGDMSRDNVHRWDGYVTYHINSDFTFAWQTTLYSKQNDYRYANHKKWATENAFVLQYHMTPDITPYIEYDYLDRQ
GVYNGRDNLSENSYRIGVSFKL
>SEQF1516_EDU87446.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKISDLNYSQHITLADNFKQKSEVLNTWRVGMNNFARNAGGQDNTRNILNPKTFLEFLVKIFTLGYVDFSKRSNEAGRN
MMAHIESSSYIKNNDGSEIMKFVMNNPEGERADSPKVIIEISLSTITTMGTRQGHTAIIFPQPDGSTNRYERKSFERKDE
SSLHLITNKVLACYQREANKEIARLLNNHQKLNNLQKLNNLQKLNNLQKLNNIQKLNNIQELNNSQELNNSQELNNSQEL
NNSQDLKNSQVSCKGSVDFTITDLLEKSLNNALLAIRNEHLLLMPHVCSESISYLLGENGILEEIDKLYELNDHGIDNDK
EGNNEINDIMINLSHILIESLDDAKVNLTPVIHSMLMTFLELPYNNDVKILEWCFNKSMQYFDDSAKIEHACSVINHINF
RRDQSKVAETLFFNLDKEPYKNSPELQELIWKKLVVYVNDFNLSNREKTYLIQRIFNNVESLFNKVPVSILVNDIFMNDF
FMKNTEMINWYFPRLLKSYEDEKIYFDKLGYNFNNKESNEEIMKNQPKDVIEEKLNNELKLRFRMMQTILKSEVNVSPFI
DQQRLNTLNPPENLRIAIEKFGWKKKTITA
>SEQF1516_EDU87447.1 orotidine 5'-phosphate decarboxylase / HUMPS family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGVRAVRDLKALYPHKIVLADAKIADAGKILSRMCFEAN
ADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLS
DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG
>SEQF1516_EDU87448.1 pemK protein 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLRARLAKRIGLAADEVVEEALLRLQAVVE
>SEQF1516_EDU87449.1 nitrogen regulatory protein P-II 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAELYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKA
AYTGKIGDGKIFVAELQRVIRIRTGEADEAAL
>SEQF1516_EDU87450.1 transporter, small conductance mechanosensitive ion channel (MscS) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQDLISHVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIILHWVVLRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGII
VNIQAVFWLQKGTEAADILTTCAQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGAVIDIGLTTVKVRNWDNTITTIP
TWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRFLDEDEMQRLNKAHLLKPYLTSRHQEINEWNRQQGSTESVLNLRR
MTNIGTFRAYLNEYLRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEEFGLRLHQS
PTGNDIRSLAGAFKQ
>SEQF1516_EDU87451.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQFTFNEGHIQLPSQWQDQSMQVLVSTDNSGINLVITREPVSQGTLTPELYQETLALYQGKLDGYTEHACREITLAEAPA
WLLDYSWNGPEDEGNQGRISQIAVFQRRGDTLLTFTFSTSLSLKNSQKTMLLEVIKSFTPLPPENDIQKDQPR
>SEQF1516_EDU87452.1 hypothetical protein ECH7EC4501_3166 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGQDGKAPALHFRPRSVMAAGDFVLRAMMSFADRSPKQDSLYK
>SEQF1516_EDU87453.1 ureidoglycolate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSHGAVRVEYYAERISKGGTNREPEFRLEETGPCSAILH
ADNAAGQVAAKMGMEHAIKTAQQNGVAVVGISRMGHSGAISYFVQQAARAGLIGISMCQSDPMVVPFGGAEIYYGTNPLA
FAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPFAVHALLPAAGPKGYGLMMMIDVLSGVLL
GLPFGRQVSSMYDDLHAGRNLGQLHVVINPNFFSSSELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRQAAVEG
IEIVDDIYQYLISDALYNTSYETKNPFAQ
>SEQF1516_EDU87454.1 alcohol dehydrogenase, iron-containing [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGVRAIAAAQTKLPPAFGLPGAKHILFRGHCSESDVQQLA
AESGDDRSVVIGVGGGALLDTAKALARRLGLPFVAAPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
NAPQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALADQQNQQLTQSFCDVVDAIIAGG
GMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGTKVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINN
QAEIDKVIAHTLRPVESIHYLPVTLTPDTLRAAFEKVESFKA
>SEQF1516_EDU87455.1 bacteriophage N4 adsorption protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDWLLDVFATWLYGLKVIAITLAVIMFISGLDDFFIDVVYWVRRIKRKLSVYRRYPRMSYRELYKPDEKPLAIMVPAWNE
TGVIGNMAELAATTLDYENYHIFVGTYPNDPDTQRDVDEVCARFPNVHKVVCARPGPTSKADCLNNVLDAITQFERSANF
AFAGFILHDAEDVISPMELRLFNYLVERKDLIQIPVYPFEREWTHFTSMTYIDEFSELHGKDVPVREALAGQVPSAGVGT
CFSRRAVTALLADGDGIAFDVQSLTEDYDIGFRLKEKGMTEIFVRFPVVDEAKEREQRKFLQHARTSNMICVREYFPDTF
STAVRQKSRWIIGIVFQGFKTHKWTSSLTLNYFLWRDRKGAISNFVSFLAMLVMIQLLLLLAYESLWPDAWHFLSIFSGS
AWLMTLLWLNFGLMVNRIVQRVIFVTGYYGLTQGLLSVLRLFWGNLINFMANWRALKQVLQHGDPRRVAWDKTTHDFPSV
TGDTRSLRPLGQILLENQVITEEQLDTALRNRVEGLRLGGSMLMQGLISAEQLAQALAEQNGVAWESIDAWQIPSSLIAE
MPASVALHYAVLPLRLENDELIVGSEDGIDPVSLAALTRKVGRKVRYVIVLRGQIVTGLRHWYARRRGHDPRAMLYNAVQ
HQWLTEQQAGEIWRQYVPHQFLFAEILTTLGHINRSAINVLLLRHERSSLPLGKFLVTEGVISQETLDRVLTIQRELQVS
MQSLLLKAGLNTEQVAQLESENEGE
>SEQF1516_EDU87456.1 large repetitive protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPASAVGALGEASYTVTANVTDSAGNSNSASHNVQVNTALPGVTINPVATDDIINAAESGNAQTISGQVTGAAAGDTVTV
TLGGKTYTATVQGNLSWSVDVPAADIQAIGNGNLTVNASVTNGVGNTGSGSRDITIDANLPGLRVDTVAGDDVVNSIEHA
QALVITGSSSGLAAGAALTVVINTVTYAATVLADGTWSVGVPAADVSNWPAGTVNITVSGTNTAGTTSTITHPVTVDLAA
VAISINTVSGDDVINAAEKGADLTLSGSTSGVEVGQTVTVTFGGKTYTATVAGDGSWTTTVPAADLSVLRDGDATVQASV
STINGNTASATHAYSVDATAPTLAINTIATDDILNAAEAGNPLTISGSSTAEAGQTVTVTLNGVTYSGSVQADGSWSVSL
PTADLSNLTASQYTVSASVSDKAGNPASANHGLAVDLTVPVLTINTVSGDDIINAAEHGQALVISGSSTGGEAGDVITVT
LNSKTYTTMLDASGNWSVGVPAADVTALGSGPQTITAAITDAAGNSDDASRTVTVNLAAPTIGINTIATDDVIKATEKGA
DLQITGTSNQPAGTTITVTLNGQNYTATTDSNGNWSATVPASAVSALGEANYTVTANVTDTAGNSNSASHNVLVNSALPA
VTINAVATDDIINAAESGNAQTISGQVTGAAQGDTVTVTLGGNTYTATVQSNLSWSVDVPAADIQALGNGDLTVNASVTN
GVGNTGSGSRDITIDANLPGLRVDTVAGDDVINSIEHNQALVITGSSSGLTAGTALTVEINNVTYGATVLADGTWSLGVP
AVDVSNWPAGTVNITVSGTNSAGTTSTITHPVTVDLAGVAITINTLSGDDVINAVEKGETLVVSGSTSGVEAGQTVTVTF
GGKNYTTTVEANGSWTVNVPPADLAALPDGAGNVQASVSNINGNSAQADRAYSVDATAPLVTINTIASDDILNVSEAGAG
ITISGTTTAQAGQTLTVTLNNNTYQTTVLADGTWSVNVPAADLSGLTASSYTVTATVSDKAGNPASADHALVVDITAPDL
TINTVAGDDIINAIEHGQALVVSGTSTGAAAGDVVTVTLNGKNYTTTLDASGNWSVGIPAADVTALATGSQTITASLSDR
AGNSDSTTHDVTVDLSGPTLTINTVSGDDIINAAEIVVAQTISGQVTGTAVAGNTVIVTIGGNQYNATVQSDLSWSVSVP
ANVLQALGNGELTISASLTNSANNTGTATHDIVIDANLPGLRVDTVAGDDVINSIEHTQALVITGSSSGLAAGAALTVVI
NSVTYGATVLADGSWSVGVPVADVTNWPAGTVNIAVSGTNTAGTTTSISHPVTVDLAAVAITINTLSTDDVINAAEKGSD
LQLSGTTSGVEAGQTITVIFGGKSYTTTVAADNTWGLTIPAVDVATLPDGAANVQASVSNVAGNSTQATHAYSVDATAPS
VTINTIATDDILNAAEAGSALTISGTSTAEAGQTVTVTLNGVNYSGNVQADGSWSVSVPTGDLASLTASSYTVNASVSDK
ARNSASATHNLTVDLAAPVVTINTVAGDDIINATEHGQAQIISGSATGATTGNTVSVTIGTTTYTTVLDANGNWSIGVPA
SVISALAQGDVTITATVTDSAGNSGTASHTVTVALGAPVLAINTIAVDDIINAAEKGADLAITGTSNQPAGTQITVTLNG
QNYTTTADASGNWSVTVPASRVSALGEATYTVTAAATDADGNSGSASHNVQVNTALPGVTINVVATDDIINAAEAGVEQT
ISGQVTGAAAGDTVTVTLGGATYTATVQANLSWSVDVPASALQELGNGELTISASVTNSVGNTGNGTREITIDANLPGLR
VDTVAGDDVVNIIEHGQALVITGSSSGLAAGSNVTLTINGQTYVAAVLADGTWSVGVPAVDVSAWPAGSVTIAASGSTSA
GNPVSVTHPVTVDLSAVAVSINAITADDVINAAEKGAALTLSGSTSGVEAGQTVTVTFGGKTYSATVAANGSWSTSVPAA
DMAALRDGDASAQASVSNVNGNSATTTHAYSVDASAPTVTINTIAGDDILNAAEAGAALTITGSSTAEAGQTVTVTLNGT
NYTGTVQTDGSWSVSVPSADLSTLTASNYTVNAAVSDKAGNPASVNHNLTVDTSVPVVTINTVAGDDVINATEHAQAQII
SGSATGAATGSTVTVTIGTNTFTTVLDASGNWSVGVPASVVSALANGTVTINASVTDAGGNSGSATHQVTVNTGLPTITF
NAISGDNILNADEKGQPLTISGGSTGLATGAQVTVTLNGHNYSATTDASGNWTLTVPVSDLAALGQANYTVSASATSAAG
NTASSQANLLVDSGLPDVTINTVAGDDIINAAEAGADQTISGVVTRAAAGDTVTVTLGGNTYTATVQSNLSWSVSVPTAD
LQALGNGDLTITASVTNANGNTGSGTRDITIDANLPGLRVDTVAGDDIVNSIEHGQALVITGGSSGLNAGAVLTVTINSV
AYSATVQADGSWSVGIPAANVSAWPAGPLTVEVDGQSSANNPVSVSHPFTVDLTAVAISINTVASDDVINAAEKGTNLTL
SGSTSGIESGQTVTVTFGGKTYTASVAANGSWSVNVPAADLATLPEGAANVQASVSSASGNSASATHAYSVDASAPTLTI
NTIASDDILNAAEAGSPLTISGTSTAETGQTVTVTLNGATYTGTVQADGSWSVSVPTSALGALNASNYTVSATVNDKAGN
PGSASHNLAVDTTAPVLTINTVAGDDIINDAEHAQALVISGTSSGGEAGDVVSVVLNGKTYTTTLDASGNWSVGVPAADV
TALGSGAQTITASVSDRAGNSDDASRTVTVSLSAPVISINTIAGDDVINATEKGSDLALSGTSDQPAGTAITVTLNGQNY
SATTDASGNWSVTVPASAVSALGEATYSVTASVTNAQGNSSTASHNVQVNTALPGITINPVATDDIINASEAGSAQTISG
QVTGAAAGSTVTVELGGKTYTATVQADLSWNVSVPAADWQALGNGELTVNASVTNAVGNTGSGTRDITIDASLPGLRVDT
VAGDDVVNIIEHAQAQVITGSSSGFAAGTALTVVINNQTYAATVLANGSWSVGVPATDVSNWPAGTLNITVSGANSAGTQ
TSITHPLTVDLTAVAISMNSITSDDAINAAEKGAALTLSGSTSGVEAGQTVTVTFGGKTYTTTVAANGSWSTTVPAADLA
ALRDGDASAQVRVTNVNGNSATATHEYSVDSAAPTVTINTIASDNIINASEAAAGVTVSGTSTAQTGQTLTVTLNGTNYQ
TTVQTDGSWSLTLPASDLTALANNGYTLTATVSDLAGNLGSASKGVTVDTTAPVISFNTVAGDDVINNVEHIQAQIISGT
ATGAVAGDRLVVTIAGQQYVTSTDASGNWSVGVPASVISGLADGTVTISATITDSAGNSSTQTHNVQVNTAAVSLSVSTI
SGDNLINAAEAGSALTLSGTGTNFATGTVVTVLLNGKGYSATIQSNGSWSVNVPAADVAALSDGTSYTVSASAQDSAGNS
ATASRSVAVDLTAPVISINTVSTDDRLNAAEQQQPLTLNGSTSAEVGQTVTVTFGGKTYTATVAANGTWALNVPAVDLAA
LGQGAQTITASVNDRAGNPGQATHALTVDTVAPTVTIATVAGDDIINNAEQLAGQTISGTTTAEVGQTVTVTFNGQTWSA
TVGSGGSWSVFIPAQQFAGLSDGSYTISATVSDQAGNPGSASRGVTLNGDVPTVTINTFAGDDVVNAAEHGSSLVISGTT
TAPVGQTLTLTLNGKTYTTTVQTGGSWSYTLGSADVTALADGNAYVINASVSNAIGNTGSSNHTITVDLSAPAMGINIDS
LQADTGLSASDFITSVSPVVVNGSLTAALASNETAQISIDGGTTWTTLTVTGTTWRYNDSRTLTDGNYLYQVRVIDAAGN
VGATDSQNVVIDTTAPDPAVKTIAISAITTDMGLITNDFVTSDTTLAVSGTLGATLSAGEFAQISLDGGVTWTTLTVVGT
SWSYADGHTLTDGTWNYTVRVVDLAGNVGQTATQNVVVDTTSPEAAKSITITGISDDTGTSSSDFITSDTTLTVRGVLGA
ALGANEFAQISTDNGATWVNVTVAADSLNWSYVDGRTLTNGTTTWQVRVVDLAGNVGATSSQSALIDTVNPAQVLTIASI
STDTGSSATDFITSDTMLTLTGSLGAGLASGEVAQISLDSGATWTTLTTNGTQWTYTDSRTLTDGSYVYQVRVLDLAGNT
GPVVSKTVVVDTINPTATPTIVSYTDDVGQRQGTLSSSQATDDTTPLLNGVLSAPLASGEVVYLYRNGLLLGAVTMVGAL
NWTYSDSGLVSGAYTYSARVVDLAGNITSSSDFVLTVDTSIPTTLAQITSQTTRDTTPIISGVITAALASGQYVEVVING
KTYTSEPGGAVVVDPAHNTWYVQLPDTDALTVSATAYTVTAQVKSSAGNGNNANISNGTVTVNAAIDYTPTWTTASKTTA
WGLTYGLDSHGMWTVLANQQVMQSTDPLTWSKTALTLYQSGNNYATSSIADYDRNGTGDLFITRDDYGTGYINGFTNNGD
GTFSSAIQVTVGTLTWYGSIVAFDKEGDGYLDFWIGDAGGPDSNTFLWNNAGTLVGNSTTSNSGGSATVGGAVTGYLSLN
EGSGVDLNNDGRIDLVQHTYNLNNYYTLSSLINQGNGTFVWGQNTTNTFLSGAGSGAMSSSVSMTWADFDGDGDMDLFLP
ASQGRANYGSLLFNTNGVLGCPVAVGATATTYASQFSLAVDWNHDGLMDIARIAQTGQSYLYTNVSNASNWTQSALGGSQ
SGTTSGVAAMDYDWDGAVDVLVSKQSGSVFLSRNTNTVSYGTSLHLRITDPNGINVYYGNTVKLYNSAGVLVATQIINPQ
SGMGVNDTSALVNFYGLNAGETYNAVLIKSTGTTASNIDQTVNTSWGGLQATDATHAYDLSAEAGTASNNGKFVGTGYND
TFFATAGTDTYDGSGGWVYSSGTGTWLANGGMDVVDFRLSTVGVTANLSSTAAQATGFNTSTFTNIEGISGSNFNDILTG
SSGDNQLEGRGGNDTLNIGNGGHDTLLYKLLNASDATGGNGSDVVNGFTVGTWEGTADTDRIDIRELLQGSGYTGNGKAS
YVNGVATLDAQAGNIGDFVKVTQSGSDTIVQIDRDGTGGTFATTNVVTLTGVHTDLATLLANHQLMVV
>SEQF1516_EDU87457.1 ferrienterobactin receptor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQNLQAPGVSTITADEIRKNPVARDVSEIIRTMPGVNLT
GNSTSGQRGNNRQIDIRGMGPENTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAA
GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLDKTQADAWDINQGHQSARAGTYA
TTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYSRQGNLYAGDTQNTNSDAYTRSKYGDETNRLYRQNYSLTWNGGWD
NGVTTSNWVQYEHTRNSRIPEGLAGGTEGKFNEKATQDFVDNDLDDVMLHSEVNLPIDFLVNQTLTLGTEWNQQRMKDLS
SNTQALTGTNTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTPGLRFDHHSIVGNNWSPALNISQGLGDDFTL
KMGIARAYKAPSLYQTNPNYILYSKGQGCYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGITWFRNDYRNKIEA
GYVAVGQNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSIIPEYTLNSTLSWQARED
LSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLSATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGA
NYIAGAGAYTYNEPGRTWYMSVNTHF
>SEQF1516_EDU87458.1 ferric enterobactin ABC transporter, ATP-binding protein FepC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVA
RRIGLLAQNATTLGDITVQELVARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ
ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIVTAELIERI
YGLRCMIIDDPVAGTPLVVPLGRTAPSTANS
>SEQF1516_EDU87459.1 [citrate (pro-3S)-lyase] ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTRDEKLIACGGIAGNIIKCVAISESVRGEGLALTLATE
LINLAYERHSTHLFIYTKTEYEALFRQCGFSTLTSVPGVMVLMENSATRLKRYAESLKKFRHPGNKIGCIAMNANPFTNG
HRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRGSEYIISRATFPCYFIKEQSVINHCYTEID
LKIFRQYLAPALGVTHRFVGTESFCRVTAQYNQDMRYWLETPTISAAPIELVEIERLRYQEMPISASRVRQLLAKNDLTA
IAPLVPAVTLHYLQNLLEHSRQDAAARQKTPA
>SEQF1516_EDU87460.1 ATP-dependent protease La [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAMDHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQM
LKLPDGTVKVLVEGLQRARISALSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKE
LGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEIL
NTDHYGLERVKDRILEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIRGHRRTYIG
SMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNVAFSDHYLEVDYDLSDVMFVATSNSMNIPAP
LLDRMEVIRLSGYTEDEKLNIAKRHLLPKQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLL
LDKSLKHIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKLTYTGSLGEVMQESIQA
ALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGIAMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLK
EKLLAAHRGGIKTVLIPFENKRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK
>SEQF1516_EDU87461.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSPRFHAWLLYRSWFGSYLRFWQKHHAMPRGVKPRAILL
ILLTFAISLWFVQMPWVRIMLLVILACLLFYMWRIPVIDEKQEKH
>SEQF1516_EDU87462.1 membrane spanning export protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNGQLQYNRGLTEPRLPRSALAVRVTAVMLLCFLGWAWYFQLDEVTTGSGTVEPSGREQVVQSLEGGILYHLDVKVGDIV
EQGQPLAQLNRTKTESDVQEAMSRLYAALATSARLRAEVSNKPLVFPDELNKFPELIESETALYNTRRDGLNKATTGLTQ
GISLVNRELAMTQPLVKQGAASSVEVLRLQRQANELENKLSDVRTQYYVQAREELAKANAEVETQRSVIRGREDSLTRLN
FTAPVRGIVQDIDVTTVGGVIAPGGKLMTIVPLDEQLLIEAKISPRDVAFIHPGQKSLVKITAYDYSIYGGLPGEVAVIS
PDTVQDEVRRDVYYYRVYIRTFSNHLENKSKQQFPIFPGMVATVDIRTGKKSVLDYLLKPFNKAQEALRER
>SEQF1516_EDU87463.1 hypothetical protein ECH7EC4501_3297 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSRQFILCGLNTTAQNDKFNAKKPGNCPVLEGISLFGGIR
>SEQF1516_EDU87464.1 YbaK/EbsC protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPAVKSLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQVYKTLLVAVNGDMKHLAVAVTPVAGQLDLKKVAKALG
AKKVEMADPMVAQRSTGYLVGGISPLGQKKRLPTIIDAPAQEFATIYVSGGKRGLDIELAAGDLAKILDAKFADIARRD
>SEQF1516_EDU87465.1 acyl-CoA thioesterase II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQALYAAKETVPEERLVHSFHSYFLRPGDSKKPIIYDVET
LRDGNSFSARRVAAIQNGKPIFYMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQIAQSLAHLLPPVLKDKFICDRPLEV
RPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIGFLEPGIQIATIDHSMWFHRPFN
LNEWLLYSVESTSASSARGFVRGEFYTQDGVLVASTVQEGVMRNHN
>SEQF1516_EDU87466.1 inosine kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLVDIEAKVDDEFIERYGLSAGHSLVIEDDVAEALYQEL
KQKNLITHQFAGGTIGNTMHNYSVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKKYNVPVVLTLGTKFVIAENPQWW
QQFLKDHVSILAMNEDEAEALTGESDPLLASDKALDWVDLVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYE
FSRAMRHKDCQNPLRVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYSSLAQVCKY
ANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR
>SEQF1516_EDU87467.1 protein YbbN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVENIVNINESNLQQVLEQSMTTPVLFYFWSERSQHCLQLTPILESLAAQYNGQFILAKLDCDAEQMIAAQFGLRAIPT
VYLFQNGQPVDGFQGPQPEEAIRALLDKVLPREEELKAQQAMQLMQEGNYTDALPLLKDAWQLSNQNGEIGLLLAETLIA
LNRSEDAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVAENPEDAALATQLALQLHQVGRNEEALELLF
GHLRKDLTAADGQTRKTFQEILAALGTGDALASKYRRQLYALLY
>SEQF1516_EDU87468.1 UDP-2,3-diacylglucosamine hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFEAWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNR
DFLLGKRFARESGMTLLPEEKVLELYGRRVLIMHGDTLCTDDAGYQAFRTKVHKPWLQTLFLALPLFVRKRIAVRMRANS
KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGAWHTEGSMVKVTADDVELIHFPF
>SEQF1516_EDU87469.1 transcriptional regulatory protein DpiA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARMMIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGD
VVFTTAASDMETVSEAVRCGVFDYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGID
PLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGRPQRIYHSG
>SEQF1516_EDU87470.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAINLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYL
DDTFMLFSSYGINMQDLQKWRKSGNRLFRCFVNATKENPASLSC
>SEQF1516_EDU87471.1 transcriptional regulator, AsnC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDKIDRKLLALLQQDCTLSLQALAEAVNLTTTPCWKRLKRLEDDGILIGKVALLDPEKIGLGLTAFVLIKTQHHSSEWY
CRFVTVVTEMPEVLGFWRMAGEYDYLMRVQVADMKRYDEFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE
>SEQF1516_EDU87472.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYVDGFVVAVPADKKDAYREMAAKAAPLFKEFGALRIVECWASDVPDGKVTDFRMAVKAEENEEVVFSWIEYPSKEVRD
AANQKMMSDPRMKEFGESMPFDGKRMIYGGFESIIDE
>SEQF1516_EDU87473.1 transporter, monovalent cation:proton antiporter-2 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHHATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAGPFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKD
LMAVKAIAIPGAIAQIAVATLLGMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLV
MVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMARSAATGSRELFTLSVLALALGIAF
GAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLPLRDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIILFGKSLAA
FFLVRLFGHSQRTALTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFALLEKYLAKTETLEEQ
TLEEAIEEEKQIPVDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSRTRVDELRERGVRAVLGNAANEEIMQLAHLE
CAKWLILTIPNGYEAGEIVASARAKNPDIEIIARAHYDDEVAYITERGANQVVMGEREIARTMLELLETPPAGEVVTG
>SEQF1516_EDU87474.1 citrate (pro-3S)-lyase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLEESVALREKDTARRMVYHALQHPLYRDIETIVRVNAL
DSEWGVNDLEAVVRGGADVVRLPKTDTAQDVLDIEKEILRIEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGI
ALGAEDYVRNLRTERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEAAHIKQLGFDGKSLINPRQIDLL
HNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNGKMVDGPVIDRARLVLSRAELSGIREE
>SEQF1516_EDU87475.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKVTINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDA
ARRIEETQKEKMASVSSGMQLPPGFKMPF
>SEQF1516_EDU87476.1 tRNA 2-selenouridine synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMNNDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRM
DAWRAACLQNPQGILCCARGGQRSHIVQSWLHAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQ
QQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQNLRLWVLEDESRMIGSNHLPECLRERMTQAAIA
VVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQEYCEYLHHGLSAIKRRLGLQRYNELAARLDAALTTQLTTGSTDG
HLAWLVPLLEEYYDPMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ
>SEQF1516_EDU87477.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENTGVALFFRTTRSVTLTAAGEHLLSQARDWLSWLESMP
SELQQVNDGVERQVNIVINNLLYNPQAVAQLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSARTLTKRVAWRLPGQKEIIVPDMETKIAAHLAGVGIGF
LPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKFGSGKAVEDIVTLFTQRRPEISGFLEIFGNPRS
>SEQF1516_EDU87478.1 hypothetical protein ECH7EC4501_3304 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMFRNGKGRESDLFLLQLQSIFLRGGFRIIAVPTHRQF
>SEQF1516_EDU87479.1 siderophore transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQIQMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYE
RKKVILLARGTCGIGFIGLCLNALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
ISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFRFLLASPLVGGIALLGGLLTMAS
AVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGALTSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLAL
FGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGVLLLLVLVE
LRRFRQTPPQVTASDG
>SEQF1516_EDU87480.1 nodulation efficiency family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMELIVVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGLVVWLVPLGWEWQGVMFAVLTLLAAWLWWKWLSRRVR
EQKHSDSHLNQRGQQLIGRRFVLESPLVNGRGHMRVGDSSWPVSASEDLGAGTHVEVIAIEGITLIIRAVIA
>SEQF1516_EDU87481.1 hypothetical protein ECH7EC4501_3288 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQWSELRANYRQKCVMCATIVDVTILLTTLPARKVSPLVH
>SEQF1516_EDU87482.1 putative outer membrane export protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARFQFKNRKNNGLIFFISFMVMGEAAIAAPLPQWANAPAVTPVAQLSLQESILRAFARNPGVTQQAAQIGIGEAQIDEA
KSAWYPHVGLTGNAGPSRQTDSSGRLDNNVSYGITLTQLVYDFGKTNNDINLQTAARDSYRFKLMATLTDVAEKTATAYM
EVSRYQALCDAAQRNIHSLENVYNMAALRANAGLNSSSDELQAQTRIAGMRSTLEQYQAQMASAKAQLAVLTGVQPEAIA
APPAELAEQPVSLKNIDYQSIPLVLAAENLRQSAQYGVEKTKAQYWPTLSIQGGKTRYQTSDRSYWDDQLQLNVNAPLYQ
GGAVSAQVQQAEGQQKISASQVEQAKLDVLQRASVAYANWTGARGREEAGLAQSESAHKTRDVYQNEYKLGKRSLNDLLT
VEQDVFQAQSAEINANYDGWVAAVNYAAAVNNLIPLAGIKQGLYNDLPDLK
>SEQF1516_EDU87483.1 hypothetical protein ECH7EC4501_3243 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEHEMISFFIYIRNHFCFLLMVFTLTTDKNALYITQMAA
>SEQF1516_EDU87484.1 glycerate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADGGEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGIT
GDGKTAVIEMAAASGLMLVAPEKRNPLLASSFGTGELIRHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQV
LVANGGNLARVASIEMEECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEMVEELEQGLQNYARVLQQQTEIN
VCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLRAVNLEQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVI
GIAGVLGDGVEVVHQYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN
>SEQF1516_EDU87485.1 oxygen-insensitive NAD(P)H nitroreductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYVFNERKILDASH
VVVFCAKTAMDDAWLKLVVDQEDADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLD
AVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV
>SEQF1516_EDU87486.1 oxidoreductase, zinc-binding dehydrogenase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKALTYHGPHHVQVENVPDPGIEQADDIILRITATAICGSDLHLYRGKIPQVKHGDIFGHEFMGEVVETGKDVKNLQKGD
RVVIPFVIACGDCFFCRLQQYAACENTNAGKGAALNKKQIPAPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
SDDKALFLSDILPTAWQAAKNAQIQQGSSVAVYGAGPVGLLTIACARLLGAEQIFVVDHHPYRLRFAADRYGAIPINFDE
DSDPAQSIIEQTAGHRGVDAVIDAVGFEAKGSTTETVLTNLKLEGSSGKALRQCIAAVRRGGIVSVPGVYAGFIHGFLFG
DAFDKGLTFKMGQTHVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAQSAEAAQKAV
SGLVNAMPGGTI
>SEQF1516_EDU87487.1 hydrolase Cof [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGRHALEMQHILGAISLDAYLITGNGTRVHSLEGELLHR
DDLPADVAELVLYQQWDTRASMHIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQI
QLHEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGNAMPQLRAEL
PHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE
>SEQF1516_EDU87488.1 sodium:sulfate symporter family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAMIVGMILEPIPATAISFIAVTICVIGSNYLLFDAKELADPAFNAQKQA
LKWGLAGFSSTTVWLVFGAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNTARTGGTVFPVI
KNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVLGLEFVSKIAGIQISWLQWFLCFLPVGVILLIIA
PWLSYVLYKPEITHSEEVATWAGDELKTMGALTRREWTLIGLVLLSLGLWVFGSEVINATAVGLLAVSLMLALHVVPWKD
ITRYNSAWNTLVNLATLVVMANGLTRSGFIDWFAGTMSTHLEGFSPNATVIVLVLVFYFAHYLFASLSAHTATMLPVILA
VGKGIPGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIYGCGYVKSKDYWRLGAIFGVIYISMLLLVGWPILAMWN
>SEQF1516_EDU87489.1 peptidylprolyl isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRVINGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTR
GTLAMARTQAPHSATAQFFINVVDNDFLNFSGESLQGWGYCVFAEVVEGMDVVDKIKGVATGRSGMHQDVPKEDVIIESV
TVSE
>SEQF1516_EDU87490.1 hypothetical protein ECH7EC4501_3246 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIGAFIFAFLQVVLLASLVHAVNVNNEIQEGLFQSGRIMVESLQHILSVQTGIH
>SEQF1516_EDU87491.1 protein RhsA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGKPAARQGDMTQYGGPIVQGSAGVRIGAPTGVACSVCPGGMTSGNPVNPLLGAKVLPGETDLALPGPLPFILSRTYSS
YRTRTPAPVGIFGPGWKAPSDIRLQLRDDALVLNDNGGRSIHFEPLLPGEAVYSRSESMWLVRGGKAAQPDGHTLARLWG
ALPPDIRLSPHLYLATNSAQGPWWILGWSERVPGAEDVLPAPLPPYRVLTGMADRFGRTLTYRREAAGDLAGEITGVTDG
AGREFRLVLTTQAQRAEEARKQHTASLSSPDTPRPLSDSAFPDTLPGTEYGPDRGIRLSAVWLTHDPAYPESLPAAPLVR
YTYTEAGELLAVYDRSNTQVRAFTYDAQHPGRMVGHRYAGRPEMRYRYDDAGRVVEQLNPAGLSYHYQYEQDRITVTDSL
NRREVLHTEGGAGLKRVVKKELADGSVTHSGYDAAGRLTAQTDAAGRRTEYGLNVVSGDITDITTPDGRETKFYYNDGNQ
LTAVVSPDGLESRRAYDEPGRLVSETSRSGETVRYRYDDAYSELPATTTDATGSTRQMTWSRYGQLLAFTDCSGYQTRYE
YDRFGQMTAVHREEGISLYRRYDNRGRLISVKDAQGHETRYEYNAAGDLTAVITPDGNRSETQYDAWGKAVSTTQGGLTR
SMEYDLAGRITTLTNENGSRSEFTYDALDRLVQQRGFDGRTQRYHYDLTGKLTQSEDEGLVTLWHYDESDRLTHRTVNGE
PAEQWQYDEHGWLTEISHLSEGHQVAVHYGYDDKGRLAGERQTVHNPETGELLWQHETEHAYNEQGLANRVTPDSLPRVE
WLTYGSGYLAGMKLGGTPLVEFTRDRLHRETVRSFGNNAYELTSTYTPAGHLQSQRLNSQVYDRDYDWNDNGDLVRISGP
RQTREYGYSATGRLESVRTLASDLDIRIPYATDPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYRHDEYGRLTEKTDR
IPAGVIRTDDERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRTGKRVWRRGRDLTGWMSLSRKPEVTWYGWDG
DRLTTVQTDTTRIQTVYEPGSFAPLIRIETDNGEREKAQRRSLAEKLQQEGSEDGHGVVFPAELVRLLDRLEEEIRADRV
SSESRAWLAQCGLTVEQLARQVEPEYTPARKVHLYHCDHRGLPLALISEDGNTAWSGEYDEWGNQLNEENPHHLHQPYRL
PGQQYDKESGLYYNRNRYYDPLQGRYITQDPIGLEGGWSLYAYPLNPVNGIDPLGLSPADVALIRRKDQLNHQRAWDILS
DTYEDMKRLNLGGTDQFFHCMAFCRVSKLNDAGVSRSAKGLGYEKEIRDYGLNLFGMYGRKVKLSHSEMIEDNKKDLAVN
DHGLTCPSTTDCSDRCSDYINPEHKETIKALQDAGYLK
>SEQF1516_EDU87492.1 chaperone protein HtpG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAADKLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISD
NGVGMTRDEVIDHLGTIAKSGTKSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEG
EYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDGETVISWEKINKAQALWTRNKSE
ITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTSLLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRF
VRGLIDSSDLPLNVSREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFANQEAIAKLL
RFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELLRKKGIEVLLLSDRIDEWMMNYLTEFDGKPF
QSVSKVDESLEKLADEVDESAKEAEKALTPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQK
VPEVKYIFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
>SEQF1516_EDU87493.1 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSNPASQIYVASKRKACEEVGFVSRSYDLPETTSEAELL
ELIDALNADNTIDGILVQLPLPAGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGL
NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPGDWIKEGAIVIDVGINRLENGKV
VGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTLQACVEYHDPQGE
>SEQF1516_EDU87494.1 isochorismatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQP
KEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTT
ATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPIPASKAALREVILPLLDESDEPFDDDNLID
YGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLSREVK
>SEQF1516_EDU87495.1 bacterial extracellular solute-binding protein, family 5 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLLNRLNQYQRLWQPSAGKPQTVTVSELAERCFCSERHVRTLLRQAQEAGWLEWQAQSGRGKRGQLRFLVTPESLRNAM
MEKALETGKQQDVLELAQLAPGELRTLLQPFMGGQWQNDTPTLRIPYYRPLEPLQPGFLPGRAEQHLAGQIFSGLTRFDN
NTQRPIGDLAHHWETSADGLRWDFYLRSTLHWHNGDAVKASHLHQRLLMLLQLPALDQLFISVKRIEVTHPQCLTFFLHR
PDYWLAHRLASYCSHLAHPQFPLIGTGPFRLTQFTAELVRLESHDYYHLRHPLLKAVEYWITPPLFEKDLGTSCRHPVQI
TIGKPEELQRVSQVSSGISLGFCYLTLRKSPRLSLWQARKVISIIHQSGLLQTLEVGENLITASHALLPGWTIPHWQVPD
EVKLPKTLTLVYHLPIELHTMAERLQATLAAEGCELTIIFHNAKNWDDTTLLAHADLMMGDRLIGEAPEYTLEQWLRCDP
LWPHVFDAPAYAHLQSTLDAVQVMPDEENRFNALKAVFSQLMTDATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFTEAW
LPAPSQ
>SEQF1516_EDU87496.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKFIFVLLTLLLVSPFSFAMKGIIWQPQNRDSQVTDTQWQGLMSQLRLQGFDTLVLQWTRYGDAFTQPEQRALLFKRAA
AAQQAGLKLIVGLNADPEFFMHQKQSSAALESYLNRLLAADLQQARLWSAVPGVTPDGWYFSAEIDDLNWRSEAARQPLL
TWLNNAQRLISDVSAKPVYISSFFAGNMSPDGYRQLLEHVKATGVNVWVQDGSGVDKLTAEQRERYLQASADCQSSAPAS
GIVYELFVAGKGKTFTAKPKPDAEIASLLAKRSSCGKDTLYFSLRYLPVAHGILEY
>SEQF1516_EDU87497.1 cation efflux system protein CusC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVNAADNYQNAGWRTFFVDNQVKTLISEALENNRDLRMA
TLKVQEARAQYRLTDADRYPQLNGEGSGSWSGNLKGDSATTREFSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRA
VHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQARGVIESTRSDIAKRQGELAQANN
ALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQILLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSD
LSSLFNASSGMWNFIPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQISAQQRYLAS
LQITLQRARALYQHGAVSYLEVLDAERSLFATRQTVLDLNYARQVNEISLYTALGGGWQQ
>SEQF1516_EDU87498.1 fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQTVAIELRNSDRSRLALGEASPTEEVDANGNVTLNFFANYRALASGVRPGVAKADAIFMINYN
>SEQF1516_EDU87499.1 enterobactin synthetase component E [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVIDGERQLSYRELNQAADNLACSLRRQGIKPGETALVQL
GNVAELYITFFALLKLGVAPVLALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVAEHSSIRVVQLLNDSGE
HNLQDAINHPADGFTATPSPADEVVYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEICQFTQQTRYLCAIPAAHNYAMSS
PGSLGVFLAGGTVVLAADPSATLCFPLIEKHQINVTALVPPAVSLWLQALTEGESRAQLASLKLLQVGGARLSATLAARI
PAEIGCQLQQVFGMAEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFRGYYKSPQH
NASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENLLLRHPAVIYAALVSMEDELMGEKSCAYLVV
KEPLRAVQVRRFLREQGIAEFKLPDRVECVDSLPLTAVGKVDKKQLRQWLASRASA
>SEQF1516_EDU87500.1 cation efflux system protein CusB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTSTAERKILFWYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSAS
GVRIDPTQTQNLGVKTATVTRGPLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGAPLLDLTIPDWVE
AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVITAFDLRAGMNIAKDNVVAKIQG
MDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTLTIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTA
SEPMLLIPSQALIDTGSEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANISGALERMRS
ESATHAH
>SEQF1516_EDU87501.1 maltose O-acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTEKEKMIAGELYRSADETLSRDRLRARQLIHRYNHSLAEEHTLRQQILADLFGQVTEAYIEPTFRCDYGYNIFLGNNF
FANFDCVMLDVCPIRIGDNCMLALGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVASGA
VVTKDVPDNVVVGGNPARIIKKL
>SEQF1516_EDU87502.1 chaperone protein FimC homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMTKIKLLMLIIFYLIISASVHAAGGIALGATRIIYPADAKQTAVWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLF
VSEPKSENTLRIIYTGPPLAADRESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSR
SGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVNSQIPLPSGVQGKLKFQTVNDYGSVTPVREVNLN
>SEQF1516_EDU87503.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEFEKIFNEMNLDRALLPILFRSNRSTVWKYLSGDSTAPASAMSLIMLLQLIQKRNPDLLAEWLTLSDFTIPPEVYLDQ
PDYWKGWVYTQHKVNKNVLEYLKKHYPDEDQKSMSKGREE
>SEQF1516_EDU87504.1 cyclic diguanylate phosphodiesterase (EAL) domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTYSSRVAIRANKVATQGKDALQELERWQGADCSEAHLM
EMRRVSYSYRYIQEVVYIDNNVPQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILPFPEMNISIITWASSKMLQKGWH
RQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDS
FIPLAQQTGLSEPLTLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIALELTEREFA
DPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVDALEYKNVTPHIIEMAKTLKLKMVAEGIETS
KQEEWLRQHGVHYGQGWLYSKALPKEDFLRWAEQHL
>SEQF1516_EDU87505.1 hypothetical protein ECH7EC4501_3267 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDDLRVIRHFSFHYLHFPQIISPLTVSAPGAFLEAIA
>SEQF1516_EDU87506.1 hypothetical protein ECH7EC4501_3133 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHSHPLYAKSAIFPGSHCSLLLQNYSVSFVGITMAEAFYILIGFLIMAAIIVMAVLYLENHS
>SEQF1516_EDU87507.1 hypothetical protein ECH7EC4501_3242 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISEINSVSGLNVKRFLMCAKMRFFDKSQFLRGLRQAGKFK
>SEQF1516_EDU87508.1 mbtH-like protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFSNPFDDPQGVFYILRNAQGQFSLWPQQCALPAGWDIVCQPQSQESCQQWLEVHWRTLTPANFTQLQEAQ
>SEQF1516_EDU87509.1 citrate lyase, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQKIEQSQRQERVAAWNRRAECDLAAFQNSPKQTYQAEKARDRKLCANLEEAIRRSGLQDGMTVSFHHAFRGGDLTVNM
VMDVIAKMGFKNLILASSSLSDCHAPLVEHIRQGVVTRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNI
DVAFLGVPSCDEFGNANGYTGKACCGSLGYAMVDADNAKQVVMLTEELLPYPHNPASIEQDQVDLIVKVDRVGDAAKIGA
GATRMTTNPRELLIARSAADVIVNSGYFKEGFSMQTGTGGASLAVTLFLEDKMRSRDIRADFALGGITATMVDLHEKGLI
RKLLDVQSFDSHAAQSLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEIDTQFNVNVLTGSDGVLRGASGGHCDT
AIASALSIIVAPLVRGRIPTLVDNVLTCITPGSSVDILVTDHGIAVNPARPELAERLQEAGIKVVSIEWLRERARLLTGE
PQPIEFTDRVVAVVRYRDGSVIDVVHQVKE
>SEQF1516_EDU87510.1 primosomal replication protein N'' [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTALLLEKLEGQLATLRQRCAPVSQFATLSARFNRHLFQTRATTLQACLDKAGDNLAALRHAVEQQQLPQVAWLAEHLA
AQLEAIAREATAWSLREWDSAPPQIARWQRKRIQHQDFERRLREMVAERRARLARVTDLVEQQTLHREVEAYEARLARCR
HALEKIENRLARLTR
>SEQF1516_EDU87511.1 hypothetical protein ECH7EC4501_3292 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVLLHEEGIASGVPEMKNEKESRKLRRLKMKTHYDSAQCVTFLHQR
>SEQF1516_EDU87512.1 recombination protein RecR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLAQALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQEN
GQICVVESPADIYAIEQTGQFSGRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAEL
CAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF
>SEQF1516_EDU87513.1 glutaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDANKLQQAVDQAYTQFHSLNGGQNADYIPFLANVPGQLAAVAIVTSDGNVYSAGDSDYRFALESISKVCTLALALEDV
GPQAVQDKIGADPTGLPFNSVIALELHGGKPLSPLVNAGAIATTSLINAENAEQRWQRILHIQQQLAGELVALSDEVNQS
EQTTNFHNRAIAWLLYSAGYLYCDAMEACDVYTRQCSTLINTVELATLGATLAAGGVNPLTHKRVLQADNVPYILAEMMM
EGLYGRSGDWAYRVGLPGKSGVGGGILAVVPGVMGIAAFSPPLDEEGNSVRGQKMVASVAKQLGYNVFKG
>SEQF1516_EDU87514.1 hypothetical protein ECH7EC4501_3161 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFIVLFLHFCHELQLSGMVVINTTHPATAKTFDPERHAVQLVN
>SEQF1516_EDU87515.1 hydroxypyruvate isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRFSANLSMLFGEYDFLARFEKAAQCGFRGVEFMFPYDYDIEELKQVLASNKLEHTLHNLPAGDWAAGERGIACIPGRE
EEFRDGVAAAIRYARALGNKNINCLVGKTPAGFSSEQIHATLVENLRYAANMLMKEDILLLIEPINHFDIPGFHLTGTRQ
ALKLIDDVGCCNLKIQYDIYHMQRMEGELTNTMTQWADKIGHLQIADNPHRGEPGTGEINYDYLFKVIENSDYNGWVGCE
YKPQTTTEAGLRWMDPYR
>SEQF1516_EDU87516.1 GumN family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLLYRVKTLWAALRGNHYTWPAIDISLPGNRHFHLIGSIHMGSHDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANL
PACEALEERISEEQLQKLQHISQEMGISPSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEG
AENQIAMLLQLPDKGLALLDDTLTHWHTNARLLQQMMSWWLNAPPQNNEITLPNTFSQSLYDVLMHQRNLAWRDKLRAMP
PGRYVVAVGALHLYGEGNLPQMLR
>SEQF1516_EDU87517.1 alkyl hydroperoxide reductase subunit F [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMMFKAQEINMLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIAELSDKVTFKEDNSLPVRKPSFLITNP
GSNQGPRFAGSPLGHEFTSLVLALLWTGGHPSKEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIK
HTAIDGGTFQNEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIVGSGPAGAAAAIY
SARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASG
AVLKARSIIVATGAKWRNMNVPGEDQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEM
KADQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIGLLPNTNWLEGAVERNRMGEI
IIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEGAKASLSAFDYLIRTKTA
>SEQF1516_EDU87518.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLHAGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALA
ILEQGEVNFIPCHHVNAVGPMGGITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLS
AALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEVMDFLSVTDQFFLNLAMAYCKAA
MDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFTAPVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPG
VTRFVGASGMEAARAVSEEMAEIYLERNMQLQIPSWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQIGAGTVRA
PLACFEQALEALAESMGIG
>SEQF1516_EDU87519.1 ribonuclease I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAFWRNAALLAVSLLPFSSANAVALQAKQYGDFDRYVLALSWQTGFCQSQHDRNRNERDECRLQTETTNKADFLTVHGL
WPGLPKSVAARGVDERRWMRFGCATRPIPNLPEARASRMCSSPETGLSLETAAKLSEVMPGAGGRSCLERYEYAKHGACF
GFDPDAYFGTMVRLNQEIKESEAGKFLADNYGKTVSRRDFDAAFAKSWGKENVKAVKLTCQGNPAYLTEIQVSIKADAIN
APLSANSFLPQPHPGNCGKTFVIDKAGY
>SEQF1516_EDU87520.1 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDMKTTHTSLPFAGHTLHFVEFDPANFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYALREYGYKCVPAIGELRQ
PVWPAEVYGSISHCGATALAVVSRQPIGVDIEEIFSAQTATELTDNIITPAEHERLADCGLAFSLALTLAFSAKESAFKA
SEIQTDAGFLDYQIISWNKQQVIIHRENEMFAVHWQIKEKIVITLCQHD
>SEQF1516_EDU87521.1 anaerobic C4-dicarboxylate transporter DcuC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTFIELLIGVVVIVGVARYIIKGYSATGVLFVGGLLLLIISAIMGHKVLPSSQASTGYSATDIVEYVKILLMSRGGDLG
MMIMMLCGFAAYMTHIGANDMVVKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
AAAAICASPAAIILAPTSGDVVLAAQASEMSLIDFAFKTTLPISIAAIIGMAIAHFFWQRYLDKKEHISHEMLDVSEITT
TAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVICMLIASILEFLRSFNTQKVFSGLEVAYRGMADAFANVVMLLVAA
GVFAQGLSTIGFIQSLISIATSFGSASIILMLVLVILTMLAAVTTGSGNAPFYAFVEMIPKLAHSSGINPAYLTIPMLQA
SNLGRTLSPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLVIVIVATELMVPGTAAAVTGK
>SEQF1516_EDU87522.1 aminotransferase, classes I and II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNNPLIPQSKLPQLGTTIFTQMSALAQQHQAINLSQGFPDFDGPRYLQERLAYHVAQGANQYAPMTGVQALREAIAQKT
ERLYGYQPDADSDITVTAGATEALYAAITALVRNGDEVICFDPSYDSYAPAIALSGGIVKRMALQPPHFRVDWQEFAALL
SERTRLVILNTPHNPSATVWQQADFAALWQAIAGHEIFVISDEVYEHINFSQQGHASVLAHPQLRERAVAVSSFGKTYHM
TGWKVGYCVAPAPISAEIRKVHQYLTFSVNTPAQLAIADMLRAEPEHYLALPDFYRQKRDILVNALNESRLEILPCEGTY
FLLVDYSAVSTLDDVEFCQWLTREHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAAERLRQL
>SEQF1516_EDU87523.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLVHMASGLAVAIALAACADKSADIQTPAPAANTSISATQQPAIQQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADA
PSKVLAQKAVRTEGKQSPFSFVLPFNPADVQPNARILLSAAITVNDKLVFITDTVQPVINQGGTKADLTLVPVQQTAVPV
QASGGATTTVPSTSPTQVNPSSAVPAPTQY
>SEQF1516_EDU87524.1 glyoxylate carboligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIRHILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAG
TDMITALYSASADSIPILCITGQAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
DLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINADAAALLQQFAELTSVPVIPTLMG
WGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFGIGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVS
DAKAALTLLVEVAQEMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTTIGLSQIAA
AQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQFLIEELAVGAQFNIPYIHVLVNNAYLGLIR
QSQRAFDMDYCVQLAFENINSSEVNGYGVDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTN
ISMGSELDNVMEFEDIADNAADAPTETCFMHYE
>SEQF1516_EDU87525.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIIHPLLASSSAPNYRQSWRLAGVWRRAINLMTESGELLTLHRQGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQG
IRLGRFTVKQPQRYCLLRITPPAHPQPLAAAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLG
KGPGLTPSHDDTLSGMLLAAWYYGALDARSGRPFFACSDNLQLVTTAVSVSYLRYAAQGYFASPLLHFVHALSCPKRTAV
AIDSLLALGHTSGADTLLGFWLGQQLLQGKP
>SEQF1516_EDU87526.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARRELELREIPYIKNSLHANYSYKSISIGSKQGWLISAKLKVPETFEPDMIFIEISDPEGFINIPDVL
>SEQF1516_EDU87527.1 putative esterase YbdB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDIRTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCV
VGTELNATHHRPVSEGKVRGVCQPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG
>SEQF1516_EDU87528.1 adenylate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVVSFIAFSKNSTHFKGIFAMRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSELGKQAKDIMDAGKLVT
DELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGINVDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPP
KVEGKDDVTGEELTTRKDDQEETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG
>SEQF1516_EDU87529.1 phosphoribosylaminoimidazole carboxylase, ATPase subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQSVITAEIERWPETALTRELARHPAFVNRDVFPIIADR
LTQKQLFDKLHLPTAPWQLLAERSEWPAVFERLGELAIVKRRTGGYDGRGQWRLRADETEQLPAECYGECIVEQGINFSG
EVSLVGARCFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELGYVGVMAMECFVTPQGLLINELA
PRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVVNNPSVMINLIGSDVNYDWLKLPLVHLHWYDKEVRPGRKVGHLNL
TDSDTSRLSATLEALIPLLPPEYASGVMWAQSKFC
>SEQF1516_EDU87530.1 multidrug ABC transporter, permease/ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPLLISYFIDNMVAKNNLPLKVVAGLAAAYVGLQLFAAG
LHYAQSLLFNRAAVGVVQQLRTDVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAM
FSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQQFRQQARFGERMGEASRSHYMA
RMQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSASGTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFE
LMDGPRQQYGNDDRPLQSGTIEVDNVSFAYRDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYPLTEGEIRL
DGRPLSSLSHSALRQGVAMVQQDPVVLADTFLANVTLGRDISEERVWQALETVQLAELARSMSDGIYTPLGEQGNNLSVG
QKQLLALARVLVETPQILILDEATASIDSGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQ
LLAAQGRYWQMYQLQLAGEELAASVREEESLSA
>SEQF1516_EDU87531.1 phenylalanine-specific permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNASNVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLGIGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVE
EPVSGSFAHFAYKYWGPFAGFLSGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGET
EFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVIMFSFGGLELIGITAAEARDPEK
SIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSNSSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLF
GLSVQGNAPKFLTRVSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRFRAAMRRQG
RETQFKALLYPFGNYLCIAFLAMILLLMCTMDDMRLSAILLPVWIVFLFVAFKTLRRK
>SEQF1516_EDU87532.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTVNVALLALIISATSSPVVLAGDTIEAAATELSAINSGMSQSEIEQKITRFLERTDNSPAAYTYLTEHHYIPSETPDT
TQTPTVQTDPDAGQKTVAATGDVQTTARYQSMINARQSAVTDAQQTQITEQQAQIVATQKTLAATGDTQNTAHYQEMINA
RLAAQNEANQRTATEQGQKMNALTTDVAVQQQNERTQYDKQMQSLAQESAQAHEQIDSLSQDVTQTHQQLTNTQKRVADN
SQQINTLNNHFSSLKNEVDDNRKEANAGTASAIAIASQPQVKTGDVMMVSAGAGTFNGESAVSVGTSFNAGTHTVLKAGI
SADTQSDFGAGVGVGYSF
>SEQF1516_EDU87533.1 apo-citrate lyase phosphoribosyl-dephospho-CoA transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFTVVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQ
EQAALVSASGPEGMLSIAAPARDLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRRCLLCEQSAAVCARGKT
HQLTDLLNRMEALLNDVDACNVN
>SEQF1516_EDU87534.1 adenine phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALSIDLLVERYKNAGINKVVGTEARGFLFGAPVALGLGV
GFVPVRKPGKLPRETISETYDLEYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFD
LGGEQRLEKQGITSYSLVPFPGH
>SEQF1516_EDU87535.1 SPFH domain/band 7 family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNAN
VTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATKMVS
EAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVMMPLEASSLMGSIAGIAELVKDSANKRTQP
>SEQF1516_EDU87536.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNLYDLKKFDLNLLVIFECIYQHLSISKAAESLYITPSAVSQSLQRLRAQFNDPLFIRSGKGIAPTTTGLNLHHHLEKN
LRGLEQTINIVNKSELKKNFIIHGPQLISCSNNSMLIRCLRQDSSVEIECHDILMSAENAEELLVHRKADLVITQMPVIS
RSVICMPLHTIRNTLICSNRHPRITDNSTYEQIMAEEFTQLISKSAGVDDIQMEIDERFMNRKISFRGSSLLTIINSIAV
TDLLGIVPYELYNSHRDFLNLKEIKLEHPLPSIKLYISYNKSSLNNLVFSRFIDRLNECF
>SEQF1516_EDU87537.1 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFAQEQYPFATEVMDVADAAQVAQVCQRLLAETERLDVLVNAA
GILRMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL
ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV
DGGSTLGA
>SEQF1516_EDU87538.1 alkyl hydroperoxide reductase subunit C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFTFVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHK
AWHSSSETIAKIKYAMIGDPTGALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAS
HPGEVCPAKWKEGEATLAPSLDLVGKI
>SEQF1516_EDU87539.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHPLETLTTAAGILLMAFLSCLLLPAPALGLTLAQKLVTTFHLMDLSQLYTLLFCLWFLVLGAIEYFVLRFIWRRWFSL
AD
>SEQF1516_EDU87540.1 allantoate amidohydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITHFRQTIEEALPWLSSFGADPAGGMTRLLYSPEWLETQQQLKKRMAASGLETRFDEVGNLYGRLSGTEYPQEVILSGS
HIDTVVNGGNLDGQFGALAARLAIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNS
FVDAMKACGFTLPDAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTVTLNGESNHAGTTPMGYRRDTVY
AFSRICHQSIEKAKKMGDPLVLTFGKVEPRPNTVNVVPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDIRIDID
LWMDEEPVPMNKDLVATLTELCESEKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITDLAEGVKTL
ALMLYQLAWQK
>SEQF1516_EDU87541.1 ferric enterobactin transport protein fepE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSLNIKQGSDAHFPDYPLASPSNNEIDLLNLISVLWRAKKTVMAVVFAFACAGLLISFILPQKWTSAAVVTPPEPVQWQ
ELEKTFTKLRVLDLDIKIDRTEAFNLFIKKFQSVSLLEEYLRSSPYVMDQLKEAKIDELDLHRAIVALSEKMKAVDDNAS
KKKDEPSLYTSWTLSFTAPTSEEAQTVLSGYIDYISALVVKESIENVRNKLEIKTQFEKEKLAQDRIKMKNQLDANIQRL
NYSLDIANAAGIKKPVYSNGQAVKDDPDFSISLGADGIERKLEIEKAVTDVAELNGELRNRQYLVEQLTKANINDVNFTP
FKYQLSPSLPVKKDGPGKAIIVILSALIGGMVACGSVLLRYAMASRKQDAMMADHLV
>SEQF1516_EDU87542.1 hypothetical protein ECH7EC4501_3163 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCGEQSPHIRLSGQSGKAPALHFRPQSVMAAGESYQMLSINRVGTEL
>SEQF1516_EDU87543.1 antimicrobial peptide resistance and lipid A acylation protein PagP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVSKYVAIFSFVFIQLISVGKVFANADEWMTTFRENIVQTWQQPEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGF
GLSRWDEKGNWHGLYAMAFKDSWNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGP
VTFQMTYIPGTYNNGNVYFAWMRFQF
>SEQF1516_EDU87544.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDSLAKAGKYLGQAAKLMIGMPDYDNYVEHMRVNHPDQTPMTYEEFFRERQDARYGGKGGARCC
>SEQF1516_EDU87545.1 potassium efflux system KefA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTMFQYYKRSRHFVFSAFIAFVFVLLCQNTAFARASSNGDLPTKADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDK
IDRVKEETVQLRQKVAEAPEKMRQATAALTALSDVDNDEETRKILSTLSLRQLETRVAQALDDLQNAQNDLASYNSQLVS
LQTQPERVQNAMYNASQQLQQIRSRLDGTDVGETALRPSQKVLMQAQQALLNAEIDQQRKSLEGNTVLQDTLQKQRDYVT
ANSARLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPDEAARIQANPLVKQELEINQQLSQRLITATENGNQLMQQNIKVKN
WLERALQSERNIKEQIAVLKGSLLLSRILYQQQQTLPSADELENMTNRIADLRLEQFEVNQQRDALFQSDAFVNKLEEGH
TNEVNSEVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQQQLMSVSKNLKSILTQQIFWVNSNRPMDWDWIKAFP
QSLKDEFKSMKITVNWEKAWPAVFIAFLAGLPLLLIAGLIHWRLGWLKAYQQKLASAVGSLRNDSQLNTPKAILIDLIRA
LPVCLIILAVGLILLTMQLNISELLWSFSKKLAIFWLVFGLCWKVLEKNGVAVRHFGMPEQQTSHWRRQIVRISLALLPI
HFWSVVAELSPLHLMDDVLGQAMIFFNLLLIAFLVWPMCRESWRDKESHTMRLVTITVLSIIPIALMVLTATGYFYTTLR
LSGRWIETVYLVIIWNLLYQTVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPPEEPTIALEQVNQQTLRITMLLMFA
LFGVMFWAIWSDLITVFSYLDSITLWHYNGTEAGAAVVKNVTMGSLLFAIIASMVAWALIRNLPGLLEVLVLSRLNMRQG
ASYAITTILNYIIIAVGAMTVFGSLGVSWDKLQWLAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGSFSGT
VSKIRIRATTITDFDRKEVIIPNKAFVTERLINWSLTDTTTRLVIRLGVAYGSDLEKVRKVLLKAATEHPRVMHEPMPEV
FFTAFGASTLDHELRLYVRELRDRSRTVDELNRTIDQLCRENDINIAFNQLEVHLHNEKGDEVTEVKRDYKGDDPTPAVG
>SEQF1516_EDU87546.1 multidrug resistance, ATP-binding protein mdlA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLFAQLSWYFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVDGVTEQHFTTGQILMWIATMVLIAVVVYLLRYVWRVL
LFGASYQLAVELREDYYRQLSRQHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIMMSTQISWQL
TLFALLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDRQSALFAADAEDTGKKNMRVARI
DARFDPTIYIAIGMANLLAIGGGSWMVVQGSLTLGQLTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAEAPV
VNDGSEPVPEGRGELDVNIHQFTYPQTDHPALENVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGDIRFHDIPL
TKLQLDSWRSRLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLASVHDDILRLPQGYDTEVGERGVMLSGGQKQR
ISIARALLVNAEILILDDALSAVDGRTEHQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRGNHDVLAQQ
SGWYRDMYRYQQLEAALDDAPENREEAVDA
>SEQF1516_EDU87547.1 type-1 fimbrial protein homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVNTDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLND
CDPVVAANAAVAFSGQADAINDNLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGT
GTSASAGQANADATFIMRYE
>SEQF1516_EDU87548.1 putative purine permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLLTLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWG
TILTITLGEASRGTPINDIATSLAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFG
IADPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSHSLSGELHWQWFPLGSGGALSPG
IILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTRYRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSF
IYGSVICLLVALVPALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMALPPVYLQD
LPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE
>SEQF1516_EDU87549.1 methylated-DNA-[protein]-cysteine S-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKEDSFPQRVWQIVAAIPEGYVTTYGDVAKLAGSPRAARQVGGVLKRLPEGSTLPWHRVVNRHGTISLTGPDLQRQRQA
LLAEGVMVSGSGQIDLQRYRWNY
>SEQF1516_EDU87550.1 acriflavine resistance protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSS
NSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSIEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL
TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSG
LKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVL
AIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL
SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLP
SSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGE
ENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG
LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVP
FSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAIS
LIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL
IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKNEDI
EHNHTVDHH
>SEQF1516_EDU87551.1 triphosphoribosyl-dephospho-CoA synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSMPATLTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDRINCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSA
EMAPEAVLHGLRPIGMACEGDMFRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQLLTPTTVCSTAASFCRGLTDRELRTN
NSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLLLMAINGDTNVASRGGEGGLRWL
QREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSPGGSADLLILTWFLAQI
>SEQF1516_EDU87552.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGAVETRKRCKIVAGQTVSFAGHSVQVVA
>SEQF1516_EDU87553.1 transcriptional regulatory protein CusR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTA
LGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVGYMLEVPDGQ
>SEQF1516_EDU87554.1 transcriptional regulator AcrR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAK
FPSDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT
RRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE
>SEQF1516_EDU87555.1 Cu(I)-responsive transcriptional regulator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNLEESGELVNLFNDPQRHSADV
KRRTLEKVAEIERHIEELQSMRNQLLALANACPGDDSADCPIIENLSGCCHHRAG
>SEQF1516_EDU87556.1 DNA-binding protein HU-beta [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFR
AGKALKDAVN
>SEQF1516_EDU87557.1 acyl-CoA thioesterase I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSASAAWPALLNDKWQSKTSVVNASISGDTSQQGLARL
PALLKQHQPRWVLVELGGNDGLRGFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDV
PLLPFLMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS
>SEQF1516_EDU87558.1 ammonium transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIATIKTGLASLAMLPGLVMAAPAVADKADNAFMMICTALVLFMTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCIL
WVVYGYSLAFGEGNNFFGNINWLMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTL
SYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPHNLPMVFTGTAILYIGWFGFNAG
SAGTANEIAALAFVNTVVATAAAILGWIFGEWALRGKPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWG
VTMLKRLLRVDDPCDVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVAFIGYKLAD
LTVGLRVPEEQEREGLDVNSHGENAYNA
>SEQF1516_EDU87559.1 cytoplasmic membrane export protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKNAQSVEAWLEAMIAVARYYRLDFSQENVRATVNWERDSKREELLTDMARQLGMGLRLVEFSADSLNPWRLPLIAVFD
NQQIGVITRRDNHDNISVQFSGDEGLETTLNVADIEDKIVELALLRPLSAIPDARVDDYIRPYQANWFWSLSLKDWRRYG
DIMLASLVANVLALAAMIFSMQVYDRVVPAQSYPTLWVLFAGVMMAILFEFCMRMVRTHLSDVIGKRADLRISDRVFGHA
LRLKNNVRSKSTGSFISQIRELESVRELITSTTIGAVADLPFFLLFVFILWMIGGWLVLVVLLALPLLVIPGLLVQRPLA
RLANEGMRESAVRNATLVEAVQSIEDIKLLRAEQRFQNQWNHTNDVASSISMKQRFLTGLLLTWTQEVQSIVYVVVLLVG
CFMVMNGDMTTGALVGTTILASRTIAPLSQISGVLSRWQQAKVARNGLDELMKRPVDQPEHGKLVHKAVLHGNYQFSNAV
FYYDEEEKIADVAIGKLNIQAGEKIAILGRNGAGKSTLLQMLAGMRIAQQGQVLLDNISIGQLDPADLRRDMGLLSQTGR
LFFGSLRENLTMGMPEASDEDIERALTLSGALPFVQKQKNGLNYMIQEGGFGLSGGQRQTLLLARLLISQPNIVLLDEPS
ASLDEMAEAYLIEQLKQWIGHRTLIIATHRTAMLQLVDRIIVMDQGRIVMDGAKEAILREQGEPTARRVVLQEKNKGSAA
>SEQF1516_EDU87560.1 YD repeat [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEGPGGPQGATAGGTLAMRMLSQRAMAASQMKRAANDKAIAQMLASKKSGPPAARLGDEIQHKSFLGALAGAVLGAIVT
IAEGCLIMAACATGPYALVLVPALMYASYKASDYVEEKQNQLESWINSFCDTDGAINTGSKNVKINGKPAARAAVTLPPP
PPPGAIPEVPQGEPSWGDIATDLLESAAEKAVPLAKAWGNAVITLTDSNAGFMDRVSAGASLLFPAGPVLMEFATMVGGR
GEIKKDVDFPEAGEDTALCDKENKPPRIAQGSSNVFINNQPAARKGDKLECSAAIVEGSPDVFIGGEQVTYLDIQPEFPP
WQRMILGGITIASYLLPPAGLLGKLGNLAKLGKLGNLLGKSGKLLGAKLGALLGKTGNSLKSIANKVIRWVTDPVDPVTG
AYCDERTDFTLGQTLPLSFTRFHSSVLPLHGLTGVGWSDSWSEYAWVREQGNRVDVISLGATLNFAFDGESDTAVNPYHA
QYILRRRDDYLELFDRDALSSRFFYDAFPGMRLRHPVTDDTSDDRLAHSPADRMYMLGGMSDTASNRITFERDTQYRITG
VSHTDGIRLKLTYHASGYLKAIHRTDNGIQTLATYEQDARLDYHLFYEYDAADRIIRWSDNDQTWSRFTYDAQGRCVTVT
GAEGYYNATLDYGDGCTTVTDGKGIHRYYYDPDGNILREEAPDGSTTTYEWDEFHHLLARHSPAGRVEKFEYNAAHGQLS
RYTAADGADWQYCYDERGLLSNITAPAGQTWTQQCDERGLPVSLVSPQGEETRLAYTPQGLLSGIFRQDERRLGIEYDHH
NWPETLTDVMGREHHTEYSGHDLPVKMRGPGGQSVRLQWQQHHKLSGLERAGTGAEGFRYDRHGNLLAYTDGNGVVWTME
YGPFDLPVARTDGEGHRWQYRYDKDTLQLTEVINPQGESYLYILDNCGRVTEERDWGGVVCRYRYDADGLCTARVNGLEE
TILYSRDAAGRLAEVITPEGKTQYAYDKSGRLTGIFSPDGTSQRTGYDERGRVNVTTQGRRAIEYHYPDEHTVIRCILPP
EDERDRHPDGSLLKTTYRYNAAGELTEVILPGDETLTFSRDEAGREVLRHSNRGFACEQGWNAAGQPVSQRAGLFPAEAT
WGGLLPSLLREYRYDSAGNVSGVTSREDYGRETHREYRLDRNGQVTAVTASGTGLGYGEGDETYGYDSCGYLKAQSAGRH
RISGETDQYAAGHRLKQAGNTQYDYDAAGRMVSRTKHRDGYRPETERFRWDSRDQLTGYRSAQGEQWEYRHDASGRRTEK
RCDRKKIRFTYLWDGDSIAEIREYRDDKLYSVRHLVFNGFELISQQFSRVRQPHPSVAPQWVTRTNHAVSDLTGRPLMLF
NSEGKTVWRPGQTSLWGLALSLPADTDYPDPRGERDPEADPGLLYAGQWQDAESGLCYNRFRYYEPETGMYLVSDPLGLQ
GGEQTYRYVPNPCGYIDPLGLAICQLARWTKWGSEQSNISDVLNSLGNRALKYANGDWIKSEAAFNKYINMINKRLELTG
SKFRVEIQPAIKNGERVPATTNGPFKVNGKWTSGTHYTGGSKRLDAGIIDITSPTNQYGLHPVIEGFDITLNKTKPSAVD
IYSDVFGGIDINDFRL
>SEQF1516_EDU87561.1 ferrochelatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLLWWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYS
RQQQQALAQRLPETPVALGMSYGSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIR
DYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTRELASALGMAPEKVMMTFQSRFGRE
PWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLETLEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR
>SEQF1516_EDU87562.1 hypothetical protein ECH7EC4501_3298 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPQTLILVKAVEQSHKNPEQYYLTIHYYFRIYQVILNHH
>SEQF1516_EDU87563.1 UDP-sugar hydrolase/5'-nucleotidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLLQRGVALALLTTFTLASEAALAYEQDKTYKITVLHTNDHHGHFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLL
SGGDINTGVPESDLQDAEPDFRGMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKR
QDLKIAVIGLTTDDTAKLGNPENFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHMGHYDNGDHGSNAPGDVEMARAL
PAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCKPDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLK
KKVTWEDGKSERVLYTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAAQMDRTGAD
FAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAVAQMKPDSGAYPQFANVSFVAKDGKLNDLKI
KGEPVDPAKTYRMATLNFNATGGDGYPRLDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ
>SEQF1516_EDU87564.1 citrate lyase acyl carrier protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDAIRTTILDVLARYNVRGVQLNVDDKGALDCILRARLE
ALLARASGIPALPWEDCQ
>SEQF1516_EDU87565.1 hypothetical protein ECH7EC4501_3193 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIHENTGFLDSDAQRCAFVCRYSEINQKIRRGRSLVQQPDQKPLTQQGLTV
>SEQF1516_EDU87566.1 thioesterase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWDGLENSDSFHWMTAHNIAFVVVNININYRRPAVLSDLLTITSQLQQLN
GKSGILSQVITLEPEGQVVADALITFVCIDLKTQKALALEGELREKLEQMVK
>SEQF1516_EDU87567.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSHNITNESLALALMLVVVAILISHKEKLALEKDILWSVGRAIIQLIIVGYVLKYIFSVDDASLTLLMVLFICFNAAWN
AQKRSKYIAKAFISSFIAITVGAGITLAVLILSGSIEFIPMQVIPIAGMIAGNAMVAVGLCYNNLGQRVISEQQQIQEKL
SLGATPKQASAILIRDSIRAALIPTVDSAKTVGLVSLPGMMSGLIFAGIDPVKAIKYQIMVTFMLLSTASLSTIIACYLT
YRKFYNSRHQLVVTQLKKK
>SEQF1516_EDU87568.1 sensor histidine kinase DpiB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQLNENKQFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTASFEDYLTLHVRDMAMNQAKIIASNDSVISEVKTRDYK
RLATIANKLQRDTDFDYVVIGDRHSIRLYHPNPEKIGYPMQFTKQGALEKGESYFITGKGSMGMAMRAKTPIFDDDGKVI
GVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIARVVRQQEALFSSVYEGLIAVDP
HGYITAINRNARKMLGLSSPGRQWLGKPIAEVVRPADFFTEQIDEKRQDVVANFNGLSVIANREAIRSGDDLLGAIISFR
SKDEISTLNAQLTQIKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGESQAQQQLIDSLREAFADRQVAGLLF
GKVQRARELGLKMIIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLRSDEGNKIVELFLSDEGDDVVIEVADQGCGV
PESLRDKIFEQGVSTRADEPGEHGIGLYLIASYVTRCGGVITLEDNDPCGTLFSIYIPKVKPNDSSINPIDR
>SEQF1516_EDU87569.1 type VI secretion system Vgr family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTGLRFTLEVDGLPPDAFAVVSFHLTQSLSSLFSLDLSLVSQQFLSLEFAQVLDKMAYLTIWQGDDVQRRVKGVVTWFE
LGENDKNQMLYSMKVHPPLWRAGLRQNFRIFQNEDIKSILGTILQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
AAEEGIFFYEEHAYKSTDQSLVLCDTVRHLPESFEIPWNPNTRTEVSTLCISQFRYSAQIRPSSVVTKDYTFKRPGWAGR
FDQEGQHQDYQRTQYEVYDYPGRFKGAHGQNFARWQMEGWRNNAETARGMSRSPEIWPGRRIVLTGHPQANLNREWQVVA
SELHGEQPQAVPGRRGAGTALENHFAVIPADRTWRPQPRLKPLVDGPQSAVVTGPEGEEIFCDEHGRVRVKFNWDRYNPA
DQDSSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTYHQENRTPGSLPGTKTQMTIRSKTYMGSGFN
ELKFDDATGREQVYIHAQKNMDTEVLNDRTTTVKHDHRETVKNDQTVTIQEGNRLLTVEKGHKITGVLKGSLSEDVFQDR
GTIAGSVHVDAVNNGGEGNGIQAYTAIKEIMLAVEESKIALTPDGIQLQVGESTVIRLSKDGITIVGGSVFIN
>SEQF1516_EDU87570.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGYLNNVTGYRDDLLANRAIVKHGNFALLTPDGLVKNIIPGFENCDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEG
IETFLYVISGNITAKAEGKTFSLSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGYAPWLVSGNASELERIHYE
GMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNNWIPVKKGDYIFMGAYSLQAGYG
VGRGEAFSYIYSKDCNRDVEI
>SEQF1516_EDU87571.1 peptidylprolyl isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAKVNDQEISRGQFENAFNSERNRMQQQLGDQYSELAAN
EGYMKTLRQQVLNRLIDEALLDQYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREATIDVNALAAKQPVTEQEIASYYEQNKNNFMTPEQFRVSYIKLDA
ATMQQPVSDADLQSYYDQHQDQFTQPQRTRYSIIQTKTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLED
ATIPDELKNAGLKEKGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDVAAKVKHEKALDAYYALQQKVSDAASNDTE
SLAGAEQAAGVKATQTGWFSKENLPEELNFKPVADAIFNGGLVGENGAPGINSDIITVDGDRAFVLRISEHKPEAVKPLA
DVQEQVKALVQHNKAEQQAKVDAEKLLVDLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMA
TDMQGNVVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ
>SEQF1516_EDU87572.1 amino acid permease family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEASTWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDF
FRRGLGNGVFSLALSLLYLLTLAVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADKVKDPQVIMPRAFLVAIGVTTLL
YISLALVLLSDVSALELEKYADTAVAQAASPLLGHVGYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKRMNKS
LWRQSTWGNIIVVVLIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVIVGFIYSLW
SQGSRALIWIIGAILLSLIVAMVMKRNKTV
>SEQF1516_EDU87573.1 ureidoglycolate hydrolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLQVLPLSQEAFSAYGDVIETQQRDFFHINNGLVERYHDLALVEILEQDRTLISINRAQPANLPLTIHELERHPLGTQA
FIPMKGEVFVVVVALGDDKPDLSTLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
>SEQF1516_EDU87574.1 putative carboxylate-amine ligase ybdK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNKITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQ
KVVLQAAADHHLEICGGGTHPFQKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPH
FIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMIDSIKDLHWDIRPSPHFGTVEVRV
MDTPLTLSHAVNMAGLIQATAHWLLTERPFKHKEKDYLLYKFNRFQACRYGLEGVITDPYTGDRRPLTEDTLRLLEKIAP
SAHKIGASSAIEALHRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD
>SEQF1516_EDU87575.1 queuosine biosynthesis protein QueC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEIDVARELALKLGARAHKVLDVTLLNELAVSSLTRDSIP
VPDYEPEADGIPNTFVPGRNILFLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKVLNHAVSLGMAKDIRFETPL
MWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKPTVMAAMKQKTGLK
>SEQF1516_EDU87576.1 oxidoreductase, short chain dehydrogenase/reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEV
IALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA
ASKYALEAWSDALRMELRRSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARFTLGPEAVVDKVRHAFISEKPKM
RYPVTLVTWAVMVLKRLLPGRVMDKILQG
>SEQF1516_EDU87577.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEIQRLLTETIESLNTREKRDNKPRFSISFIRKHPGLFIGMYVAFFATLAVMLQSETLSGSVWLLVVLFILLNGFFFFD
VYPRYRYEDIDVLDFRVCYNGEWYNTRFVPAALVEAILNSPRVADVHKEQLQKMIVRKGELSFYDIFTLARAESTS
>SEQF1516_EDU87578.1 acriflavine resistance protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNLKSDTRGLHMNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVTVKTEPLQITTELPGRTSAYRIAEV
RPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALA
DAQQANAAVTAAKAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQSSNDFLRLKQ
ELANGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITLRAIFPNPDHTLLPGMFVRARLEEGLNPNAILV
PQQGVTRTPRGDATVLVVGADDKVETRPIVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTADNNQQAAS
GAQPEQSKS
>SEQF1516_EDU87579.1 enterobactin synthetase component F [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQHLPLVAAQPGIWMAEKLSELPSAWSVAHYVELTGEVDAPLLARAVVAGLAQADTLRMRFTEDNGEVWQWVDDALIFE
LPEIIDLRTNIDPHGTAQALMQADLQQDLRVDSGKPLVFHQLIQVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCAL
LRGEQTPASPFTPFADVVEEYQQYRESEAWQRDAAFWAEQRRQLPPPASLSPAPLAGRSASADILRLKLEFTDGEFRQLA
TQLSGVQRTDLALALAAFWLGRLCNRMDYAAGFIFMRRLGSAALTATGPVLNVLPLGIHIAAQETLPELATRLAAQLKKM
RRHQRYDAEQIVRDSGRAAGDEPLFGPVLNIKVFDYQLDIPGVQAQTHTLATGPVNDLELALFPDEHGDLSIEILANKQH
YDEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPGEYAQLAQINATQVEIPETTLSALVAEQAAKTPDAPALADARYQ
FSYREMREQVVALANLLREHGVKPGDSVAVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTD
DQLPRFADVPDLTNLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRLLWMQNHYPLTGEDVVA
QKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFFAEYGVTTTHFVPSMLAAFVASLTPQTARQNCATLKQVF
CSGEALPADLCREWQQLTGAPLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPIGYPVWNTGLRILDAMMHPVPPGVAG
DLYLTGIQLAQGYLGRPDLTASRFIADPFVPGERMYRTGDVARWLDNGAVEYLGRSDDQLKIRGQRIELGEIDRVMQALP
DVEQAVTHACVINQAAATGGDARQLVGYLVSQSGLPLDTSALQAQLRETLPPHMAPVVLLQLPQLPLSANGKLDRKALPL
PELKAQTPGRAPKAGSETIIAAAFASLLGCDVQDADADFFALGGHSLLAMKLAAQLSRQFARQVTPGQVMVASTVAKLAT
IIDGEEDSSRRMGFETILPLREGNGPTLFCFHPASGFAWQFSVLSRYLDPLWSIIGIQSPRPHGPMQTATNLDEVCEAHL
ATLLEQQPHGPYYLLGYSLGGTLAQGIAARLRARGEQVAFLGLLDTWPPETQNWQEKEANGLDPEVLAEINREREAFLAA
QQGSTSTELFTTIEGNYADAVRLLTTAHSVPFDGKATLFVAERTLQEGMSPERAWSPWIAELDIYRQDCAHVDIISPGAF
EKIGPIIRATLNR
>SEQF1516_EDU87580.1 haemolysin expression modulating protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFYSAADHRLAELTMNKLYDKIPSSVWKFIR
>SEQF1516_EDU87581.1 thiol:disulfide interchange protein DsbG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKKILLLALLPAIAFAEELPAPVKAIEKQGITIIKTFDAPGGMKGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENL
SNTLIEKEIYAPAGREMWQRMEQSHWLLDGKKDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGVIKPESP
ATAAAILASKDPAKTWQEYEASGGKLKLNVPANVSTEQMKVLSDNEKLMDDLGANVTPAIYYMSKENTLQQAVGLPDQKT
LNIIMGNK
>SEQF1516_EDU87582.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNVIELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPW
SRLATPVIACHSRTPEVFRLAANHSKQQPSKPCEAELTRALLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQLCGYSSTSYFISVFKAFYGLTP
LNYLAKQRQKVMW
>SEQF1516_EDU87583.1 2-hydroxy-3-oxopropionate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAVNVDTARQVTEAADIIFIMVPDTPQVEEVLFGENGCT
KASLKGKTIVDMSSISPIETKRFARQVNELGGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVG
GNGDGQTCKVANQIIVALNIEAVSEALLFASKAGADPVRVRQALMGGFASSRILEVHGERMIKRTFNPGFKIALHQKDLN
LALQSAKALALNLPNTATCQELFNTCAANGGSQLDHSALVQALELMANHKLA
>SEQF1516_EDU87584.1 hypothetical protein ECH7EC4501_3178 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIAYWQNDNFVIFLSPENQSLASKVGGIKSPEIMSLCLLVNFCHFVWPLR
>SEQF1516_EDU87585.1 phosphoadenosine phosphosulfate reductase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIYKIPLPLNILEAARERITWTLNTLPRVCVSFSGGKDSGLMLHLTAELARQMGKKICVLFIDWEAQFSCTINYVQSLR
ELYTDVIEEFYWVALPLTTQNSLSQYQPEWQCWEPDVEWVRQPPQDAITDPDFFCFYQPGMTFEQFVREFAEWFSQKRPA
AMMIGIRADESYNRFVAIASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTWYANHQSLCNPLYNLMYQAGVPL
RHMRICEPFGPEQRQGLWLYHVIEPDRWAAMCARVSGVKSGGIYAGHDNHFYGHRKILKPEHLDWQEYALLLLNSMPEKT
AEHYRNKIAIYLHWYQKKGIEVPQTQQGDIGAKDIPSWRRICKVLLNNDYWCRALSFSPTKAKNYQRYNERIKGKRQEWG
ILCNND
>SEQF1516_EDU87586.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQENSPLLQLQNVGYLAGDAKILNNINFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDVSTLKPEIYR
QQVSYCAQTPTLFGDTVYDNLIFPWQIRNQQPDPAIFLDFLERFALPDSILTKNIAELSGGEKQRISLIRNLQFMPKVLL
LDEITSALDESNKHNVNEMIHRYVREQNIAVLWVTHDKDEINHADKVITLQPHAGEMQEARYELA
>SEQF1516_EDU87587.1 DNA polymerase III, tau subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCR
EIEQGRFVDLIEIDAASRTKVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ
KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDALSLTDQAIASGDGQVSTQAVSAM
LGTLDDDQALSLVEAMVEANGERVMALINEAAARGIEWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTI
PPTDIQLYYQTLLIGRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVAPTAVMTPTQVPPQPQSAPQQA
PTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERLASVTDRVQARPVPSALEKAPAKKEAYRWKA
TTPVMQQKEVVATPKALKKALEHEKTPELAAKLAAEAIERDAWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQ
RHLNNRGAQQKLAEALSMLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQTLRRFFDAELDEDSI
RPI
>SEQF1516_EDU87588.1 YD repeat [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTASGTGLGYGEGDESYGYDSCGYLKAQSAGGHRISEETDQYAGGHRLKQAGNTQYDYDAAGRMVSRTRHRDGYRPETER
FRWDSRDQLTGYCSAQGEQWEYRHDASGRRTEKRCDRKKIRFTYLWDGDSIAEIREYRDDELYSVRHLVFNGFELISQQC
SRVRQPHPSVAPQWVTRTNHAVNDLTGRPLMLFNSEGKTVWRPGQTSLWGLALSLPADTDYPDPRGERDAEADPGLLYAG
QWQDAESGLCYNRFRYYEPETGMYLVSDPLGLQGGEQTYRYVPNPCGWVDPLGLAASSKISSLMDYIGDGRRVSGHTGFL
DGVRLSRSQINNIAKEMEKLGIKVIRKADKYLPPNARAAFDYGLRNIYLRKNATLYEVYHEVIHAKQFAKIGREAYEALG
RLSREEHVLNEILKSKNLFNEAEIAHAIKYVEGLREKFMMGLIN
>SEQF1516_EDU87589.1 copper-exporting ATPase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSITEAHVTGTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPS
EALTAVSEALPAATADDDDSQQLLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG
AEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSLWLVIGLITLAVMVFAGGHFYRS
AWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQWFPMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDL
TPPTARLVTDEGEKSVPLAEVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGTVVQDGSVL
FRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALVSAAIWYFFGPAPQIVYTLVIATTVLIIACP
CALGLATPMSIISGVGRAAEFGVLVRDADALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADFDEAQALRLAAALEQGS
SHPLARAILDKASDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNDQQVDTKAIEADISAQASQGATPVLLAVDGK
AVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANAIAKEAGIDEVIAGVLPDGKAEAIKRLQSEGRQVAMVGD
GINDAPALAQADVGIAMGGGSDVAIETAAITLMRHSLMGVADALAISRATLRNMKQNLLGAFIYNSIGIPVAAGILWPFT
GTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE
>SEQF1516_EDU87590.1 sensor histidine kinase CusS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFAEQDINDLKEISATLERVLNHPDETQARRLMTLEDIV
SGYSNVLISLADSHGKTVYHSPGAPDIREFARDAIPDKDARGGEVFLLSGPTMMMPGHGHGHMEHSNWRMISLPVGPLVD
GKPIYTLYIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSRQIQNITSKDLDVRLDPQTVPIE
LEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTPITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLF
LAQADNNQLIPEKKMLNLADEVGKVFDFFEALAEDRGVELQFVGDECQVAGDPLMLRRALSNLLSNALRYTPPGEAIVVR
CQTVDHLVQVIVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVKSIVVAHKGTVAVTSNARGTRFVIVLPE
RG
>SEQF1516_EDU87591.1 fimbriae Z protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKV
LFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRY
LVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLYELI
>SEQF1516_EDU87592.1 acetyl esterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGTIAEQRQYYTLERRFWNAGAPEMATKAYMVPTKYGQVETRLFCPQ
PDSPATLFYLHGGGFILGNLDTHDRIMRLLASYSQCTVIGIDYTLSPEARFPQVIEEIVAACCYFHQQAEDYQINMSRIG
FAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQQDLQMYEEAYLSNDADRESPYY
CLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLAAHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL
>SEQF1516_EDU87593.1 fosmidomycin resistance protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMSEQTQPVAGAAASTTKARTSFGILGAISLSHLLNDMIQSLILAIYPLLQSEFSLTFMQIGMITLTFQLASSLLQPVV
GYWTDKYPMPWSLPIGMCFTLSGLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
SSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIINPLPRNKVVLAVSILLILIFSKY
FYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAVAAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGV
LTVIIGFILASAFSAILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLLGMLTIFLP
DNRHKD
>SEQF1516_EDU87594.1 competence protein ComEA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHGIKALLITLSLACAGMSHSALAAASVAKPTAVETKAEAPAAQNKAAVPAKASDEEGSRVSINNASAEELARAMNGVG
LKKAQAIVSYREEYGPFKTVEDLKQVPGMGNSLVERNLAVLTL
>SEQF1516_EDU87595.1 hypothetical protein ECH7EC4501_3120 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILISIHRQFIGHIFSLSFRNFLLFTLGPGDRKNYADIH
>SEQF1516_EDU87596.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEIDLLYENIYQLLIKPYLLDLSSQSGKKIELNYTCKIKDAADEIKGSMIFNDVDGKQKATCTIRVLILKTFHDGRYRF
VIESVIYDLINNYSGFILTGRLFWQGEGFGHELFPVTNKYNAWRWKNKKIIDISW
>SEQF1516_EDU87597.1 ferric enterobactin ABC transporter, permease protein FepG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIYVSRRLLITCLLLISACVVAGIWGLRSGAVTLEISQVFAALMGDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIF
QSLMRNPLGSPDVMGFNTGAWSGVLVAMVLFGQDLTAIALAAMVGGIITSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVERSRLLMML
VAVVLTAAATALAGPISFIALVAPHIARRISGTARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLI
VLLIQESRKK
>SEQF1516_EDU87598.1 enterochelin esterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEEYSTIKRVWIYITGVTDHHQNSQPQSMQRIAGTDVWQWT
TQLNANWRGSYCFIPTERDDIFSAPSPDRLELREGWRKLLPQAIADPLNPQSWKGGRGHAVSALEMPQAPLQPGWDCPQA
PEIPAKEIIWKSERLKNSRRVWIFTTGDVTAEERPLAVLLDGEFWAQSMPVWPVLISLTHRQQLPPAVYVLIDAIDTTHR
AHELPCNADFWLAVQQELLPLVKAIAPFSDRADRTVVAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWWPHRGGQQEGV
LLEKLKAGEVSAEGLRIVLEAGIREPMIMRANQALYAQLHPIKESIFWRQVDGGHDALCWRGGLMQGLIDLWQPLFHDRS
>SEQF1516_EDU87599.1 ISEc4, transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELKKLMEHISIIPDYRQAWKVEHKLSDILLLTICAVISGAEGWEDIEDLGETHLNFLKQYGDFENGIPVHDTIARVVSC
ISPAKFHECFINWMRDCHSSDDKDVIAIDGKTLRHSYDKSRRRRAIHVISAFSTMHSLVIGQIKTDEKSNEITAIPELLN
MLDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAVKGNQGRLNKAFEEKFPLKELNNPEHDSYAMSEKSHGREEIRLHIV
CDVPDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKESEMTVRYYISSADLTAEKFATAIRNHWHVENKLHWRLDVVVNED
DCKIRRGNAAELFSGIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVFAGSGLS
>SEQF1516_EDU87600.1 bacterial FdrA protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQA
IMQQLEEALKQLAQGSGSSQALTQVRRWDSACQKLPDANLALISVAGEYAAELANQALDRNLNVMMFSDNVTLEDEIQLK
TRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGEGITHAIGLGGRDLSREVGGISA
LTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMKATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTA
RRNAIMPASSGFICGLYTGGTLAAEAAGLLAGHLGVEADDAHHHGMMLDADGHQIIDLGDDFYTVGRPHPMIDPTLRNQL
ITDLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARSDNQPLYAIATVTGTERDPQCRSQQIATLEDAGIAVVS
SLPEATLLAAALIHPLSPAAQQHTPSLLENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ
>SEQF1516_EDU87601.1 cation efflux system protein CusF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVVKGFDLESKKITIHHDPIAAVNWPEMTMRFTITPQTK
MSGIKTGDKVAFNFVQQGNLSLLQDIKVSQ
>SEQF1516_EDU87602.1 carbamate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYRLAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAES
QGMIGYMLAQSLSAQPQMPPVTTVRTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
RKILDSEAIELLLKEGHVVICSGGGGVPVTDDGAGSEAVIDKDLAAALLAEQINADGLVILTDADAVYENWGMPQQRAIR
HATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAWIGALSRIEETLAGEAGTCISL
>SEQF1516_EDU87603.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKQSLHETAKRLALELPFVELCWPFGPEFDVFKIGGKIFMLSSELRGVPFINLKSDPQKSLLNQQIYPSIKPGYHMNKK
HWISVYPGEEISEALLRDLINDSWNLVVDGLAKRDQKRVRPG
>SEQF1516_EDU87604.1 Hok/Gef family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVLAYEPKK
>SEQF1516_EDU87605.1 universal stress protein G [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYKTIIMPVDVFEMELSDKAVRHAEFLAQDDGVIHLLHVLPGSASLSLHRFAADVRRFEEHLQHEAEERLQTMVSHFTID
PSRIKQHVRFGSVRDEVNELAEELGADVVVIGSRNPSISTHLLGSNASSVIRHANLPVLVVR
>SEQF1516_EDU87606.1 immunoglobulin-binding regulator family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGDTMQQRLTQDLTQFLASLPEDDRINAINEIRMAIHQVSPFREEPVDCVLWVKNSQLMPNDYNPNNVAPPEKKLLKKSI
EIDGFTQPIVVTHTDKNALEIVDGFHRHEIGKGSSSLKLRLKGYLPVTCLEGTRNQRIAATIRHNRARGRHQITAMSEIV
RELSQLGWDDNKIGKELGMDSDEVLRLKQINGLQELFADRQYSRAWTVK
>SEQF1516_EDU87607.1 carbon starvation protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKSGKYLVWTVLSVMGAFALGYIALNRGEQINALWIVVASVCIYLIAYRFYGLYIAKNVLAVDPTRMTPAVRHNDGLDY
VPTDKKVLFGHHFAAIAGAGPLVGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAG
VIALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLALFMGIYLRYLRPGRIGEVSVIGLVFLIFAIISGGWVA
ESPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLLAPRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPV
WTGNLFPFLFITIACGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFAMNSPMAVL
APAGTADVVASAAQVVSSWGFAITPDTLNQIASEVGEQSIISRAGGAPTLAVGMAYILHGALGGMMDVAFWYHFAILFEA
LFILTAVDAGTRAARFMLQDLLGVVSPGLKRTDSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAG
MALMLCAVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSPDAKVGFLAIANKFQAMIDSGNIPSQYTESQLAQLVF
NNRLDAGLTIFFMVVVVVLALFSIKTALAALKEPKPTAKETPYEPMPENVEEIVVQAKGAH
>SEQF1516_EDU87608.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMNSSIKSFSLLAVILLAGCSSPTSRIADCQAQGVSHDTCYLAEQQRQAAILSASEAQAFKNAEAAQHAQAAKKAIYKGF
GMTFRMSSKNFAYLNDSLCAIDEDNKDATVYQSGLYNVIVYHHTGKVALMKEGQFVGYLK
>SEQF1516_EDU87609.1 NCS1 nucleoside transporter family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEHQRKLFQQRGYSEDLLPKTQSQRTWKTFNYFTLWMGSVHNVPNYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVLN
GAAGSKYGVPFAMILRASYGVRGALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGGDFTLLGLSLPGLI
TFLLFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMAIWAISLVGLGPIFDYIPSGIQKAENSGFLFLVVINAVVAVW
AAPAVSASDFTQNAHSFREQALGQTLGLVVAYILFAVAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILMT
TISTNATGNIIPAGYQIAAIAPTKLTYKNGVLIASIISLLICPWKLMENQDSIYLFLDIIGGMLGPVIGVMMAHYFVVMR
GQINLDELYTAPGDYKYYDNGFNLTAFSVTLVAVILSLGGKFIPLMEPLSRVSWFVGVIVAFA
>SEQF1516_EDU87610.1 cation efflux system protein cusA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAK
TVRGFSQFGDSYVYVIFEDGTDPYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQ
DWFLKYELKTIPDVAEVASVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELAEAEYMVRASGYLQTL
DDFNHIVLKASENGVPVYLRDVAKIQVGPEMRRGIAELNGEVVGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGVEIV
TTYDRSQLIDRAIDNLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGA
MVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITNASVEVGPALFISLLIITLSFIPIFTLEGQEGRLFGPLAFTK
TYAMAGAALLAIVVIPILMGYWIRGKIPPESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFL
PQINEGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQEQWRPGMTM
DKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADIDAMAEQIEEVARTVPGVASALAERLEGGR
YINVEINREKAARYGMTVADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITLADVA
DVKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPMTLMI
IFVLLYLAFRRVGEALLIISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLNNPQ
TFSEQKLDEALHHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKLMWLHR
HRVRK
>SEQF1516_EDU87611.1 outer membrane usher protein SfmD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIPTTTDIPQRYTWCLAGICYSSLAILPSFLSYAESYFNPAFLLENGTFVADLSRFERGNHQPAGVYRVDLWRNDEFIG
SQDIVFESTTENTGDKSGGLMPCFNQVLLERIGLNSSAFPELAQQQNNKCINLLKAVPDATINFDFAAMRLNITIPQIAL
LSSAHGYIPPEEWDEGIPALLLNYNFTGNRGNGNDSYFFSELSGINIGPWRLRNNGSWNYFRGNGYHSEQWNNIGTWVQR
AIIPLKSELVMGDGNTGSDIFDGVGFRGVRLYSSDNMYPDSQQGFAPTVRGIARTAAQLTIRQNGFIIYQSYVSPGAFEI
TDLHPTSSNGDLDVTIDERDGNQQNYTIPYSTVPILQREGRFKFDLTAGDFRSGNSQQSSPFFFQGTALGGLPQEFTAYG
GTQLSANYTAFLLGLGRNLGNWGAVSLDVTHARSQLADDSRHEGDSIRFLYAKSMNTFGTNFQLMGYRYSTQGFYTLDDV
AYRRMEGYEYDYDYDGEHRDEPIIVNYHNLRFSRKDRLQLNISQSLNDFGSLYISGTHQKYWNTSDSDTWYQVGYTSSWV
GISYSLSFSWNESVGIPDNERIVGLNVSVPFNVLTKRRYTRENALDRAYASFNANRNSNGQNSWLAGVGGTLLEGHNLSY
HVSQGDTSNNGYTGSATANWQAAYGTLGVGYNYDRDQHDVNWQLSGGVVGHENGITLSQPLGDTNVLIKAPGAGGVRIEN
QTGILTDWRGYAVMPYATVYRYNRIALDTNTMGNSIDVEKNISSVVPTQGALVRANFDTRIGVRALITVTQGGKPVPFGS
LVRENSTGITSMVGDDGQVYLSGAPLSGELLVQWGDGANSRCIAHYVLPKQSLQQAVTVISAVCTHPGS
>SEQF1516_EDU87612.1 ferrienterobactin ABC transporter, ferrienterobactin-binding periplasmic protein FepB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLAPLYRNALLLTGLLFSGIAAVQAADWPRQITDSRGTHTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVA
DDQGFLRQWSKVAKERKLQRLYIGEPSTEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQALLTQLG
EITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQMLEQLGFTLAKLPAGLNASQSQG
KRHDIIQLGGENLAAGLNGESLFLFAGDQKDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERLKALF
>SEQF1516_EDU87613.1 isochorismate synthase, entC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAVNGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPF
DPRQPSSLYIPESWQSFSRQEKQASARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDA
AIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARRQPDEVLDREAGNRLLASEKDRH
EHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWHLATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELE
PFDRELFGGIVGWCDSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH
>SEQF1516_EDU87614.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLSFNFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRR
WFRAGLIRCWLFLTVSLLSHSLLDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTAYGHQVIISELMWVWLP
GMLLMGMLWWRRR
>SEQF1516_EDU87615.1 efflux ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIARWFWREWRSPSLLIVWLALSLAVACVLALGNISDRMEKGLSQQSREFMAGDRALRSSREVPQAWLEEAQKRGLKVGK
QLTFATMTFAGDTPQLANVKAVDDIYPMYGDLQTNPPGLKPQAGSVLLAPRLMALLNLKTGDTIDVGDATLRIAGEVIQE
PDSGFNPFQMAPRLMMNLADVDKTGAVQPGSRVTWRYKFGGSENQLDSYEKWLLPQLKPEQRWYGLEQDEGALGRSMERS
QQFLLLSALLTLLLAVAAVAVAMNHYCRSRYDLVAILKTLGAGRAQLRKLIVGQWLMVLTLSAVTGGAIGLLFENVLMVL
LKPVLPAALPPASLWPWLWALGTMTVISLLVGLRPYRLLLATQPLRVLRNYVVANVWPLKFYLPIVSVVVVLLLAGLMGG
SMLLWAVLAGAVVLALLCGVLGWMLLNVLRRMTLKSLPLRLAVSRLLRQPWSTLSQLSAFSLSFMLLALLLVLRGDLLDR
WQQQLPPESPNYFLINIATEQVTPLKAFLAEHQIVPESFYPVVRARLTAINGKPTEGNEDEALNRELNLTWQNTRPDHNP
IVAGNWPPKADEVSMEEGLAKRLNVTLGDTVTFMGDTQEFRAKVTSLRKVDWESLRPNFYFIFPEGALDGQPQSWLTSFR
WENGNGMLTQLNRQFPTISLLDIGAILKQVGQVLEQVSRALEVMVVLVTACGMLLLLAQVQVGMRQRHQELVVWRTLGAG
KKLLRTTLWCEFAMLGFVSGLVAAIGAETALAVLQAKVFDFPWEPDWRLWIVLPCSGALLLSLFGGWLGARLVKGKALFR
QFAG
>SEQF1516_EDU87616.1 regulator of nucleoside diphosphate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRPTIIINDLDAERIDILLEQPAYAGLPIADALNAELDRAQMCSPEEMPHDVVTMNSRVKFRNLSDGEVRVRTLVYPAK
MTDSNTQLSVMAPVGAALLGLRVGDSIHWELPGGVATHLEVLELEYQPEAAGDYLL
>SEQF1516_EDU87617.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLENAPDDVKLAVDLIVLLEENQIPARTVLRALDIVKRDYEKKLQSDEASQSE
>SEQF1516_EDU87618.1 transcriptional regulator AllR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHN
RDVLSVAGPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKALLYPLAEEELMSIILQ
TGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCIASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVR
DTARDISTALGLKAHP
>SEQF1516_EDU87619.1 addiction module antidote protein, HigA family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIQYVLVSLFTGKQQLKTMKQATRKPTTPGDILLYEYLEPLDLKINELAELLHVHRNSVSALINNNRKLTTEMAFRLAKV
FDTTVDFWLNLQAAVDLWEVENNMRTQEELGRIETVAEYLARREERAKKVA
>SEQF1516_EDU87620.1 ferric enterobactin transport system permease protein fepD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAFSGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGAL
MQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALNSLSLGSDTATALGSRVARTQLI
GLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAP
VLIFLVRRKTRGGA
>SEQF1516_EDU87621.1 phosphoribosylaminoimidazole carboxylase, catalytic subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSAHRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMI
AAKTLVPVLGVPVQSAALSGVDSLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVL
ENPDPRGAA
>SEQF1516_EDU87622.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPAENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALVGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHNMDEE
ARAKLRAKHVGFVFQSFMLIPTLNALENVELPALLRGESSAESRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARA
FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLIMVTHDLQLAARCDRCLRLVNGQLQEEA
>SEQF1516_EDU87623.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVIGPFINASAILLGGMLGALLSQRLPERIRVSMTSIFGLASLGIGILLVVKCANLPAMVLATLLGALIGEICLLEKGVN
TAVAKAQNLFRHSRKKPAHESFIQNYVAIIVLFCASGTGIFGAMNEGMTGDPSILIAKSFLDFFTAMIFACSLGIAVSVI
SIPLLIIQLTLAWAAALILPLTTPSMMADFSAVGGLLLLATGLRICGIKMFPVVNMLPALLLAMPLSAAWTAWFA
>SEQF1516_EDU87624.1 hypothetical protein ECH7EC4501_2098 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRPWLRKVPVYTLPSLCCNLAPNNSEFGDHASVAIFSPGSGLVR
>SEQF1516_EDU87625.1 phosphoglycerate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTIELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNY
LKDKLSNPVRLVKDYLDGVDVAEGELVVLENVRFNKGEKKDDEILSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADV
ACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIANTFIAAQGHDVGKSLYEADLVD
EAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVNDVKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRK
GTEIVANAIADSEAFSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK
>SEQF1516_EDU87626.1 multifunctional CCA protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGRDFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAP
DVTLEDDLKRRDLTINALAQDDNGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLTLM
REMTHAGELEHLTPERVWKETENALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPAPARWHPEIDTGIHTLMTLSMAA
MLSPQVDVRFTTLCHDLGKGLTPPELWPRHHGHGPAGVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIV
KLFDSIDAWRKPQRVEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREELTRRRIAAV
ASWKEQRCPKPE
>SEQF1516_EDU87627.1 glycogen synthesis protein GlgS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTWFCARYAWYCQQMMQTRELELEH
>SEQF1516_EDU87628.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIELTVNGLNVQAQYHDEEIERVHKPLLRMLAALQTVNPQRRTVVFLCAPPGTGKSTLTTFWAYLAQQDPELPAIQTLP
MDGFHHYNSWLDAHQLRPFKGAPETFDVAKLAENLRQVVEGDCTWPQYDRQKHDPVEDALHVTAPIIIVEGNWLLLDDDN
WRQLAQFCDFSIFINAPATALRERLVGRKLAGGLSLADAEAFYDRTDGPNVRRVLEESLPANLTLMMTATGEYRLVD
>SEQF1516_EDU87629.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNPIGINNLSQSSNIANATGDEVVSLDKHINTSATDKVQIQAFIVSTWMASFQNDMYSEDNPISPYHKIEW
>SEQF1516_EDU87630.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDVRQSIHSAHAKTLETQGLRNEFLVEKVFVADEYTMVYSHIDRIIIGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGV
INIGGAGTITVDGQCYEIGHRDALYVGKGAKEVVFASIDTGTPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNR
RTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISP
SWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKDLR
>SEQF1516_EDU87631.1 iron ABC transporter, ATP binding protein FitB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAHNAKGQGLILDNVSAGYHKKIIVDGVSFSVPTEKMTVLVGANGCGKSTLLSTIARVLQPMGGSILLDGKAIHEQPTKA
LSRRLGILPQSPLLPEGLTVYELVSRGRFPWQNFIRQWSDADEQAVEEALKLTGTQEFAHLPVEKLSGGQRQRCWIAMVL
AQKTPYILLDEPTTWLDLRYQVEILELLHDLTRHHGRTVVVVLHDLNFAVNYGDTLIFLRQGKVVRVLNEGEHCTPELVK
AVFDVDVHASINTLTGKPFFMPFRGVEKV
>SEQF1516_EDU87632.1 phosphoglycerate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDDEQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIG
CFCIGTNQVDLDAAAKRGIPVFNAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG
HIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTKNMMGAKEISLMKPGSLLINASR
GTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDPFTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGS
TLSAVNFPEVSLPLHGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEKALQAMKAI
PGTIRARLLY
>SEQF1516_EDU87633.1 alanine racemase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIAEAIDAGQRQFGENYVQEGVDKIRHFQELGVTGLEWH
FIGPLQSNKSRLVAEHFDWCHTIDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRL
RGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTMVRIGTAIFGARDYSKK
>SEQF1516_EDU87634.1 type III secretion apparatus protein EpaQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDDIVFAGNRALYLILVMSAGPIAVATFVGLLVGLFQTVTQLQEQTLPFGVKLLCVSICFFLMSGWYGEKLYSFGIEMLN
LAFARG
>SEQF1516_EDU87635.1 IS629 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQHDDWLKREIQRVYDENHQVYGVRKVWRQLLREGI
RVARCTVARLMAVMGLAGVLRGKKVRTTISRKAVAAGDRVNRQFVAERPDQLWVADFTYVSTWQGFVYVAFIIDVFAGYI
VGWRVSSSMETTFVLDALEQALWARRPSGTIHHSDKGSQYVSLAYTERLKEAGLLASTGSTGDSYDNAMAESINGLYKAE
VIHRKSWKNRAEVELATLTWVDWYNNRRLLGRLGHTPPAEAEKAYYASIGNDDLAA
>SEQF1516_EDU87636.1 ISSfl3 OrfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSQTKKDIPCFRSYLPDALRLRFEDKLTIRAIAQRLGLSHSTIHTLFQRFIASGIAWPLPDSVSLAQLDAILYANRKKE
LTEPQISEGTWRKERRTSYSREFKIRLVKQALQPGAVVARIAREHGINDNLLLKWKSQYEDGLLSDDDIQECMPVPVALT
DTPEPTRPVTNPFWRNKPDECPESDPGNVPRCELHLKSGVVKLFDPLTPEMLRALIREMKGGTR
>SEQF1516_EDU87637.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKFAAVIAVMALCSAPVMAAEQGGFSGPSATQSQAGGFQGPNGSVTTVESAKSLRDDTWVTLRGNIVERISDDLYVFKD
ASGTINVDIDHKRWNGVTVTPKDTVEIQGEVDKDWNSVEIDVKQIRKVNP
>SEQF1516_EDU87638.1 arginine decarboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSQEASKMLRTYNIAWWGNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRSINAA
FKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLAHAGMTRSVIVCNGYKDREYIRLALIG
EKMGHKVYLVIEKMSEIAIVLDEAERLNVVPRLGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSL
QLLHFHLGSQMANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNEYANNIIWAIGDA
CEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPAEDAPRALQSMWETWQEMHEPGTRRSLREWLHDSQM
DLHDIHIGYSSGTFSLQERAWAEQLYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFP
VLPLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVGAYQEILGNMHNLFGDTEAVD
VFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQFRDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDE
>SEQF1516_EDU87639.1 SPFH/band 7 domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDDIVNSVPSWMFTAIIAVCILFIIGIIFARLYRRASAEQAFVRTGLGGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVS
RSTIDSLITKDRMRVDVVVAFFVRVKPSVEGIATAAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENF
VQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRRERNEVEQDVEVAVREKNRDALS
RKLEIEQQEAFMTLEQEQQVKTRTAEQNAKIAAFEAERRREAEQTRILAERQIQETEIDREQAVRSRKVEAEREVRIKEI
EQQQVTEIANQTKSIAIAAKSEQQSQAEARANLALAEAVSAQQNVETTRQTAEADRAKQVALIAAAQDAETKAVELTVRA
KAEKEAAEMQAAAIVELAEATRKKGLAEAEAQRALNDAINVLSDEQTSLKFKLALLQALPAVIEKSVEPMKSIDGIKIIQ
VDGLNRGGTAGDANTGNVGGGNLAEQALSAALSYRTQAPLIDSLLNEIGVSGGSLAALTSLLTPTTPVAENVE
>SEQF1516_EDU87640.1 TonB-dependent outer membrane ferric coprogen receptor FitA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKFTPSFSGIKGRALFSLLFAAPMIHATDTATTKDGETITVTADANTATEATDGYQPLSTSTATLTDMPMLDIPQVVNT
VSDQVLENQNATTLDEALYNVSNVVQTNTLGGTQDAFVRRGFGANRDGSIMTNGLRTVLPRSFNAATERVEVLKGPASTL
YGILDPGGLINVVTKRPEKTFHGSVSATSSSFGGGTGQLDITGPIEGTQLAYRLTGEVQDEDYWRNFGKERSTFIAPSLT
WFGDNATVTMLYSHRDYKTPFDRGTIFDLTTKQPVNVDRKIRFDEPFNITDGQSDLAQLNAEYHLNSQWTARFDYSYSQD
KYSDNQARVTAYDATTGTLTRRVDATQGSTQRMHSTRADLQGNVDIAGFYNEILGGVSYEYYDLLRTDMIRCKNAKDFNI
YNPVYGNTSKCTTVSASDSDQTIKQESYSAYAQDALYLTDNWIAVAGIRYQYYTQYAGKGRPFNVNTDSRDEQWTPKLGL
VYKLTPSVSLFANYSQTFMPQSSIASYIGDLPPESSNAYEVGAKFELFDGITADIALFDIHKRNVLYTESIGDETIAKTA
GRVRSRGVEVDLAGALTENINIIASYGYTDAKVLEDPDYAGKPLPNVPRHTGSLFLTYDIHNMPGNNTLTFGGGGHCVSR
RSATNGADYYLPGYFVADAFAAYKMKLQYPVTLQLNVKNLFDKTYYTSSIATNNLGNQIGDPREVQFTVKMEF
>SEQF1516_EDU87641.1 hydrogenase-2 small chain [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTGDNTLIHSHGINRRDFMKLCAALAATMGLSSKAAAEMAESVTNPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLE
TISLEYHEVLSAAFGHQVEENKHNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAW
GGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKNRPTFAYGRLIHEHCERRPHFDA
GRFAKEFGDEGHREGWCLYHLGCKGPETYGNCSTLQFCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVENQTPRSQ
KPDVNAKEGGNVSAGAIGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE
>SEQF1516_EDU87642.1 tRNA-modifying protein ygfZ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYLQGQVTADVSQMTDDQHLLAAHCDAKGKMWSNLRLFRDGD
GFAWIERRSVREPQLAELKKYAVFSKVTIAPDDERVLLGVAGFQARAALANIFSELPSKEKQVVKEGATTLLWFEHPAER
FLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQALGGISFKKGCYTGQEMVARAKF
RGANKRALWLLTGSASRLPEAGEDLELKMGENWRRTGTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLCIEPL
PYSLEE
>SEQF1516_EDU87643.1 glutathione synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLYLINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLADL
DVILMRKDPPFDTEFIYATYILERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILK
PLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEPVPYCLARIPQGGETRGNLAAGG
RGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIGDRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQ
>SEQF1516_EDU87644.1 hydrogenase-2 operon protein HybE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEEIAGFQTSPKAQVQAAFEEIARRSMHALSFLHPSMPVYVSDFTLFEGQWTGCVITPWMLSAVIFPGPDQLWPLRKVS
EKIGLQLPYGTMTFTVGELDGVSQYLSCSLMSPLSHSMSIEEGQRLTDDCARMILSLPVTNPDVPHAGRRALLFGRRSGE
NA
>SEQF1516_EDU87645.1 dienelactone hydrolase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRLTAKDFPQELLDYYDYYAHGKISKREFLNLAAKYAVGGMTALALFDLLKPNYALATQVEFTDPEIFAEYITYPSPNG
HGEVRGYLVKPAKMSGKTPAVVVVHENRGLNPYIEDVARRVAKAGYIALAPDGLNSVGGYPGNDDKGRELQQQVDPTKLM
NDFFAAIEFMQRYPQATGKVGITGFCYGGGVSNAAAVAYPELACAVPFYGRQAPTADVAKIEAPLLLHFAELDTRINEGW
PAYEAALKANNKVYEAYIYPGVNHGFHNDSTPRYDKSAADLAWQRTLKWFDKYLS
>SEQF1516_EDU87646.1 hydrogenase 2 maturation peptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRILVLGVGNILLTDEAIGVRIVEALEQRYILPDYVEILDGGTAGMELLGDMANRDHLIIADAIVSKKSAPGTMMILRDE
EVPALFTNKISPHQLGLADVLSALRFTGEFPKKLTLVGVIPESLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPRE
AIHD
>SEQF1516_EDU87647.1 ribose 5-phosphate isomerase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKGQIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYV
DGADEINGHMQMIKGGGAALTREKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGV
VTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIVK
>SEQF1516_EDU87648.1 esterase YqiA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYPSDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQ
CFMLPAVVVNPAVRPFELLTDYLGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYA
SCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL
>SEQF1516_EDU87649.1 flavodoxin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLMEQYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGK
IVALYGLGDQLGYGEWFLDALGMLHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSW
CEQILNEMAEHYA
>SEQF1516_EDU87650.1 IS66 family element, Orf1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAIAPSLSTSTQTRVSASSCKVEFRHGNMTLENPSPELLTMLIRELSGRGR
>SEQF1516_EDU87651.1 oxidoreductase, aldo/keto reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL
LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
KALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQGLLTGKYLNGIPE
DSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSWLLKDERVTSVLVGASRAEQLEENVQALNNLTF
STEELAQIDQHIADGELNLWQASSDK
>SEQF1516_EDU87652.1 radical SAM domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDSCDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGII
AQPDWSSKDDFMRLGKPNLFFGVTAGNMDSMINRYTADRRLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILG
GIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGEPISEIRDVRNTAIIVKEALPGWSGVDST
RLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKAVTVQPPRPKPWEKTYVLLPSFEKVKGDKVLYAHASRILHHETNP
GCARALMQKHGDRYVWINPPAIPLSTEEMDSVFALPYKRVPHPAYGNARIPAYEMIRFSVNIMRGCFGGCSFCSITEHEG
RIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAEQTCRRLSCVYPDICPHMDTNHEPTINLYRR
ARDLKGIKKILIASGVRYDIAVEDPRYIKELATHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDTYSKQAGKE
QYLIPYFISAHPGTRDEDMVNLALWLKKHRFRLDQVQNFYPSPLANSTTMYYTGKNPLAKIGYKSEDVFVPKGDKQRRLH
KALLRYHDPANWPLIRQALEAMGKKHLIGSRRDCLVPAPTIEEMREARRQNRNTRPALTKHTPMATQCQTPATAKKASST
QSRPVNAGAKKRPKAAVGR
>SEQF1516_EDU87653.1 hypothetical protein ECH7EC4501_2118 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDLILKLSKSSIYSTKPVCVSPAQKYQSSVLKNSIKIITYLSNIGCL
>SEQF1516_EDU87654.1 bacterial extracellular solute-binding protein, family 5 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYTRNLLWLVSLVSAAPLYAADVPTNTQLAPQQVFRYNNHSDPGTLDPQKVEENTAAQIVLDLFEGLVWMDGEGQVQPAQ
AERWEILDGGRRYIFHLRSGLQWSDGQPLTAEDFVLGWQRAVDPKTASPFAGYLAQAHINNAAAIVAGKADVTSLGVKAT
DDRTLEVTLEQPVPWFTTMLAWPTLFPVPHHVIAKHGDSWSKPENMVYNGAFVLDQWVVNEKITARKNPKYRDAQHTVLQ
QVEYLALDNSVTGYNRYRAGEVDLTWVPAQQIPAIEKSLPGEIRIIPRLNSEYYNFNLEKPPFNDVRVRRALYLTVDRQL
IAQKVLGLRTPATTLTPPEVKGFSATTFDELQKPMSERVAMAKALLKQAGYDASHPLRFELFYNKYDLHEKTAIALSSEW
KKWLGAQVTLRTMEWKTYLDARRAGDFMLSRQSWDATYNDASSFLNTLKSDSEENVGHWKNAQYDALLNQAMQITDATKR
NALYQQAEVIVNQQAPLIPIYYQPLIKLLKPYVGGFPLHNPQDYVYSKELYIKAH
>SEQF1516_EDU87655.1 aspartate/ornithine carbamoyltransferase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAVLKALRAENISTKVFNSGLGISVFRDNSTRTRFSYAS
ALNLLGLAQQDLDEGKSQIAHGETVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQ
CDIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFGMDVTLAHPEGYDLIPDVVEVA
KNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKVMEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELT
RDGEALYMHCLPADISGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQERVK
>SEQF1516_EDU87656.1 A/G-specific adenine glycosylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPPTTVNSVTMQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQVATVIPYFERFMARFPTVTDLANAPL
DEVLHLWTGLGYYARARNLHKAAQQVATLHGGKFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYA
VSGWPGKKEVENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAATNNSWSLYPGKKPKQTLPE
RTGYFLLLQHEDEVLLAQRPPSGLWGGLYCFPQFADEESLRQWLAQRQIAADNLTQLTAFRHTFSHFHLDIVPMWLPVSS
FTGCMDEGNALWYNLAQPPSVGLAAPVERLLQQLRTGAPV
>SEQF1516_EDU87657.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVEGVDNGFEGGTLFTQRLCAFGFVPDIRLFQLGVYFFQTLFLGVVVKDTP
>SEQF1516_EDU87658.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNKTANVAAHAVVNAALAVVQGNNARASAAGAATGDVVGMIATEMCGISPGTVTCKR
>SEQF1516_EDU87659.1 TonB-system energizer ExbB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSKSVEFFNQKRRLKREQQLLAEARSLNQANDIAADFGS
KSLSLHLLNEAQNELELSEGSDDNEGIKERTSFRLERRVAAVGRQMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNVFARQIGGFKAMLGDVAAQVLLLQSRDLDLEASAAAHPVRVAQK
LRAG
>SEQF1516_EDU87660.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARSHFSSQALVLIVISIAINMIGGQLASMVKLPIFLDSIGTLISAVLLGPVIGMLTGLLTNLLWGLLTDPIAAAFAPVA
MVIGLVAGWLARAGWFRTLPKVVVSGVIITLAVTVVAVPLRTALFGGVTGSGADLFVAWMHSMGQNLVESVAITVIGANL
VDKTLTAVIVWLLLRQLPIRTTRHFPAMAAVR
>SEQF1516_EDU87661.1 type III secretion apparatus protein EprJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVSNMPPIDRAEQSTAHEIQQAKVIDLNDRVLNLDNPDDKMISAFANYAVQTENWQQNALQALTSDKKGLTPEKLLVLQ
DHVLNYNVEVSLVGTLARKIVAAVETLTRS
>SEQF1516_EDU87662.1 iron ABC transporter, periplasmic iron-binding protein FitE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLFFSLLILLSFFARATEPVQVFTDDLGRKVTVPAHPKRIVSLHDLDITIPLIELGVPPVASHGRTRPDGSHFIRSGAL
LTGVDFDNSSIAFIGTADIDIEAIVAAKPDLIITEPTRNTPIERLEKIAPTVSIDHLKGGAPEIYRKLAELTGTQSQLAI
LERRYQAQINALKATLDSQKITVSVIQANQGKINVMHSYHSLGRVLRDAGFRFPPLIESIPEGGRMDVSAERLPELDADF
VFATWRGDTGGKPQDELAAMEKVMPGWCQFLTACRSGRYVLISREEAISNSFASLGLMAAQIQSQIAGRPLPEAK
>SEQF1516_EDU87663.1 PTS system, mannitol-specific cryptic EIICB component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENKSARAKVQAFGGFLTAMVIPNIGAFIAWGFITALFIPTGWLPNEHFAKIVGPMITYLLPVMIGSTGGHLVGGKRGAV
MGGIGTIGVIVGAEIPMFLGSMIMGPLGGLVIKYVDKALEKRIPAGFEMVINNFSLGIAGMLLCLLGFEVIGPAVLIANT
FVKECIEALVHAGYLPLLSVINEPAKVLFLNNAIDQGVYYPLGMQQASVNGKSIFFMVASNPGPGLGLLLAFTLFGKGMS
KRSAPGAMIIHFLGGIHELYFPYVLMKPLTIIAMIAGGMSGTWMFNLLDGGLVAGPSPGSIFAYLALTPKGSFLATIAGV
TVGTLVSFAITSLILKMEKTVETESEDEFAQSANAVKAMKQEGAFSLSRVKRIAFVCDAGMGSSAMGATTFRKRLEKAGL
AIEVKHYAIENVPADADIVVTHASLEGRVKRVTDKPLILINNYIGDPKLDTLFNQLTAEHKH
>SEQF1516_EDU87664.1 L(+)-tartrate dehydratase, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAETSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFF
VKVGSRFPLLGELQSILKQAVEEATIKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIVPDGDDAEIEVYMAGGGCTLPG
RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPIGSRHPNPKAAELELRLEEGLNR
LGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTGCWAHRRGTLLVHADLTFENLSHTRSAL
>SEQF1516_EDU87665.1 flagellum-specific ATP synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLKLLNKYSYLHSINGSLIEAELDDVSVGEVCEIYASRQANERIARAQVVGFRNGKTLLNLIGSSVGLTRTAVLKPTG
EQLTIQISDAFLGSVLNASGQIMERFVPDTPGDRGNLRLIDELPPSYQERRVINTPLETRIRVIDGVLTCGIGQRVGIFA
SAGCGKTVLMHMLVNNTEADVFVIGLIGERGREVTECAESLKKSVNAAKCVLVYATSDFSSVDRCNAALMATTVAEYFRD
RGKRVVLFIDSMTRYARALRDMKLAAGEPPARRGYPASVFDSLPRLLERPGPTLKGSITEFYTVLLEGEDESDPLGDEIR
SILDGHIYLSRKLAGQGHYPAIDVLKSVSRVFGQVTDEKHRDNAARVRKNLTTLEDLQVFIDLGEYRAGQNAENDFAMNA
RPKLTNWLKQSVNEKMPMSETLKELERIVK
>SEQF1516_EDU87666.1 galactose-proton symporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDAKKQGQSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIADEFQITSHTQEWVVSSMMFGAAVGAVGSGWLSFKLG
RKKSLMIGAILFVAGSLFSAAAPNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLS
DTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFVDAERVLLRLRDTSAEAKRELDEIRESLQVKQSGWA
LFKENSNFRRAVFLGVLLQVMQQFTGMNVIMYYAPKIFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTL
TLGFLVMAAGMGVLGTMMHIGIHSPSAQYFAIAMLLMFIVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTATNWIANMI
VGATFLTMLNTLGNANTFWVYAGLNVLFILLTLWLVPETKHVSLEHIERNLMKGRKLREIGAHD
>SEQF1516_EDU87667.1 methylmalonyl-CoA decarboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSYQYVNVVTINKVAVIEFNYGRKLNALSKVFIDDLMQALSDLNRPEIRCIILRAPSGSKVFSAGHDIHELPSGGRDPLS
YDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIMSSDLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKEL
IFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEELRVLGEAHTMNSDEFERIQGMRRAVYDS
EDYQEGMNAFLEKRKPNFVGH
>SEQF1516_EDU87668.1 amidohydrolase family protein SsnA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLILKNVTAVQLHPAKVQEGVDIAIENDVIVAIGDALTQRYPDASYKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPS
PDFISTLKNLWWRLDRALDEESLYYSGLICSLEAIKSGCTSVIDHHASPAYIGGSLSTLRDAFLKVGLRAMTCFETTDRN
NGIKELQEGVEENIRFARQIDEAKKAATEPYLVEAHIGAHAPFTVPDAGLEMLREAVNATGRGLHIHAAEDLYDVSYSHH
WYGKDLLARLAQFDLIDSKTLVAHGLYLSKDDIALLNQRDAFLVHNARSNMNNHVGYNHHLSDIRNLALGTDGIGSDMFE
EMKFAFFKHRDAGGPLWPDSFAKALTNGNELMSRNFGAKFGLLEAGYKADLTICDYNSPTPLLADNIAGHIAFGMGSGSV
HSVMVNGVMVYEDRQFNFDCDSIYAQARKAAASMWRRMDALA
>SEQF1516_EDU87669.1 dihydroneopterin aldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKSDNVADCLSYADIAETVVSHVEGARFALVERVAEEVA
ELLLARFNSPWVRIKLSKPGAVARAANVGVIIERGNNLKENN
>SEQF1516_EDU87670.1 hydrogenase-2 electron transfer subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRRNFIKAASCGALLTGALPSVSHAAAENRPPIPGSLGMLYDSTLCVGCQACVTKCQDINFPERNPQGEQTWSNNDKLS
PYTNNIIQVWTSGTGVNKDQEENGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVP
KYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRLALKPGSEYHYPRQTLKSGDTYL
HTVPKYYPHLYGEKEGGGTQVLVLTGVPYENLDLPKLDDLSTGARSENIQHTLYKGMMLPLAVLAGLTVLVRRNTKNDHH
DGGDDHES
>SEQF1516_EDU87671.1 sigma-54 dependent transcriptional regulator, Fis family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLYRVAGTGAYGKFLGRQLSGNSRLLCHVLETKTEKVVTQSRF
DPLCEGCDSKENCREKAFLGTPVILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
IFATMIDNMDQGVLVVDDESRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTHGHMQHIVSWDDKSELIIGQLHN
IQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGECRVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRR
NKPFIAINCAAIPEQLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAREILPIGAS
SPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQEDIELLVHYFLHLHTRRLGSVYPGIAPDVVEI
LRKHRWPGNLRELSNLMEYLVNVVPSGEVIDSTLLPPNLLNNGTTEQSDVTEVTEAHLSLDDAGGTALEEMEKQMIREAL
SRHNSKKQVADELGIGIATLYRKIKKYELLNT
>SEQF1516_EDU87672.1 Xaa-Pro aminopeptidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNR
VRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADEIVNSALEKLRKGSRQNLTAP
ATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENG
CILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVR
IMVSGLVKLGILKGDIDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDADVPEQYR
GIGIRIEDDIVITETGNENLTASVVKKPEEIEALMAAARKQ
>SEQF1516_EDU87673.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVIQDIIAALWQHDFAALADPHIVSVVYFVMFATLFLENGLLPASFLPGDSLLILAGALIAQGVMDFLPTIAILTAAAS
LGCWLSYIQGRWLGNTKTVKGWLAQLPAKYHQRATCMFDRHGLLALLAGRFLAFVRTLLPTMAGISGLPNRRFQFFNWLS
GLLWVSVVTSFGYALSMIPFVKRHEDQVMTFLMILPIALLTAGLLGTLFVVIKKKYCNA
>SEQF1516_EDU87674.1 twitching motility family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPGYAQYRSFSEDLSMNMEEIVALSVKHNVSDLHLCSAWPARWRIRGLMEAAPFDAPDVEELLREWLDDDQRAILLENGQ
LDFAVSLTENQRLRGSAFAQRHGISLALRLLPSHCPQLEQLGTPPILPELLKSENGLILVTGATGSGKSTTLAAMVGYLN
QHADAHILTLEDPVEYLYASQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETGHLVLATL
HTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAVLSQKLEVDKQEGRVALFELLINTPAVGNLIREGKTHQLPHVIQTG
QQVGMITFQQSYQQRVGEGRL
>SEQF1516_EDU87675.1 hypothetical protein ECH7EC4501_2045 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFCSPGVSLLLSAPGKCFFLHYDTILCQVAYTAAVGG
>SEQF1516_EDU87676.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYNKKNKTGTVALSGTWQQGNRESKSIRRNIEYTWVENYDTAHLTSKKVNKFEIMDQVDDDRLAELIPDFYVFPEKSVSY
NILKQGKHAFILSIGNRAIMHCAR
>SEQF1516_EDU87677.1 outer membrane protein TolC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLLPILIGLSLSGFSSLSQAENLMQVYQQARLSNPELRKSAADRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDAN
GINSNATSASLQLTQSIFDMSKWRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLD
QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAALNVENFKTDKPQPVNALLKEAEK
RNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTASSGISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMV
NSQVKQAQYNFVGASEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIVDVLDATTT
LYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPENVAPQTPEQNAIADGYAPDSPAPVVQQTSA
RTTTSNGHNPFRN
>SEQF1516_EDU87678.1 hypothetical protein ECH7EC4501_2032 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKAILRAEKMSKNTKSKIRDIRKYNAKTEVKLVYFK
>SEQF1516_EDU87679.1 IS66 family element, transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQLDKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTL
TGRVYDPAVQRPLRQTRTRKPFPESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
DAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELRRSLLSGWVDACCRLLSPLEEALHGYVMT
DGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNAGSALAPAVWFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELY
RNGGITEAACWAHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWLREKMKT
LSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKNFLFFGSDHGGERGALLYSLIGTCKLNDVDP
ESYLRHVLGVIADWPVNRVSELLPWRIALPAE
>SEQF1516_EDU87680.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPKLRLIGLTLLALSATAVSHAEETRYVSDELNTWVRSGPGDHYRLVGTVNAGEEVTLLQTDANTNYAQVKDSSGRTAWI
PLKQLSTEPSLRSRVPDLENQVKTLTDKLTNIDNTWNQRTAEMQQKVAQSDSVINGLKEENQKLKNELIVAQKKVDAASV
QLDDKQRTIIMQWFMYGGGVLGLGLLLGLVLPHLIPSRKRKDRWMN
>SEQF1516_EDU87681.1 type III secretion apparatus needle protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADWNGYIMDISKQFDQGVDDLNQQVEKALEDLATNPSDPKFLAEYQSALAEYTLYRNAQSNVVKAYKDLDSAIIQNFR
>SEQF1516_EDU87682.1 transcriptional regulatory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYWIINDNIEFWPEHRKLISVHNADLNVVLTTPASRCLSLLLEAFPDVVAQQDFFTRVWEEEGMRVPTNTLYQNISIIRR
GFRAVGDTTHSLIATVPRRGFKIHNDINIQNHVINSSTDAHTHNAPPAIKVNAGYKESIGGAKNFNNKILKHIKSYLIML
SAFVIGAYSAYWLWNNNQPKPFFKDYKTVAEINGCHFNVTEDTIDGLKEFDKYKTRILDSGINCKKYPWLYFPLAKSSPG
MIVMACNKNYNQHEVAGCLTLSYREVNRG
>SEQF1516_EDU87683.1 putative secreted protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIHVEHVGVLERAREVSRLEDIITEDNEDIEAEMPKMRDDPAGKEARFLQATDEMSAALTQFMKKKIYEEQLANFLDGE
EYVLEDQPIEKTDKVMEALKAATTHDYEVYSFAKKLFPDESDLVVVLRAILRKKQISENVRLNAEALLRKVNQETTKKFI
NSGINSALKAKLFGQALSLNPKLLRASYRQFLMAEDDAVDTYVEWIGSYGYQNRMLVTKFIKETLFSDINALDASCSSLE
FGMFLNKLSQLLSLQSAEALFLKTLMNNPIIKKFISAEDYWIFFLISLIKFPETAEELLNNALVTLPADANYKDKTLLLK
AIYSGCTNLPFSLFINNEQLLEIRECCKQAIKVTFAAELFDTQNCNKKQNKKPWKKVMFNV
>SEQF1516_EDU87684.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFKVIALAALMGISGMAAQANELPDGPHIVTSGTASVDAVPDIATLAIEVNVAAKDAATAKKQADERVAQYISFLELNQ
IAKKDISSANLRTQPDYDYQDGKSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKA
AIDNAIHQAQELANGFHRKLGPVYSVRYHVSNYQPSPMVRMMKADAAPVSAQETYEQAAIQFDDQVDVVFQLEPVDQQPA
KTPAAQ
>SEQF1516_EDU87685.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIDPKKIEQIARQVHESMPKGIREFGEDVEKKIRQTLQAQLTRLDLVSREEFDVQTQVLLRTREKLALLEQRSSELEARN
NSVADLQSPPAIPPIDKAE
>SEQF1516_EDU87686.1 hypothetical protein ECH7EC4501_2204 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYFAKHCHSLLWRNIHSYFRVDSRTVNYIFTVAKNIKPHF
>SEQF1516_EDU87687.1 molybdenum hydroxylase accessory protein, YgfJ family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAIDCIITAAGLSSRMGQWKMMLPWQQGTILDTSIKNALQFCSRIILVTGYRGNELHERYANQSNITIIHNPDYAQGLL
TSVKAAVPAVQTEHCFLTHGDMPTLTIDIFRKIWSLRNDGAILPLHNGIPGHPILVSKPCLMQAIKRPNITNMRQALLMG
AHYSVEVENAEIILDIDTPDDFITAQKRYTKI
>SEQF1516_EDU87688.1 hypothetical protein ECH7EC4501_2023 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFFDFFYGNISKHNRDREINSQQFKGFIFWEVASQKAQIA
>SEQF1516_EDU87689.1 hypothetical protein ECH7EC4501_2076 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCFLFKPRAAFYTPQWQKIAKDKYAECRHCQEKFPATFLTE
>SEQF1516_EDU87690.1 protein SprT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEEATSCSHLFFALSSAAMKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRGTSAGTAWLESYEIRLNPV
LLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWMMESVLGVPARRTHQFELQSVRRNTFPYSCKCQEHQLTVRR
HNRVVRGEAVYRCVHCGEQLVAK
>SEQF1516_EDU87691.1 transcriptional activator protein LysR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAVNLRHIEIFHAVMTAGSLTEAAHLLHTSQPTVSRELARFEKVIGLKLFERVRGRLHPTVQGLRLFEEVQRSWYGLDR
IVSAAESLREFRQGELSIACLPVFSQSFLPQLLQPFLVRYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHTPAGTER
TELLSLDELCVLPPGHPLAVKKVLTPDDFQGENYISLSRTDSYRQLLDQLFTEHQVKRRMIVETHSAASVCAMVRAGVGV
SVVNPLTALDYAASGLVVRRFSIAVPFTVSLIRPLHRPSSALVQAFSEHLQAGLPKLVTSLDAILSSATTA
>SEQF1516_EDU87692.1 fructose-bisphosphate aldolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSINAVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQ
GAAILGAISGAHHVHQMAEHYGVPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSK
YLERMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFTIAASFGNVHGVYKPGNVVLTPT
ILRDSQEYVSKKHNLPHNSLNFVFHGGSGSTAQEIKDSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKG
EDQPNKKYYDPRVWLRAGQTSMIARLEKAFQELNAIDVL
>SEQF1516_EDU87693.1 transcriptional regulatory protein QseB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALEERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK
>SEQF1516_EDU87694.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNHFGKGLMAGLKATHADSAVNVTKFCADYKRGFVLGYSHRMYEKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNS
CSTLRFFMAGYRLEN
>SEQF1516_EDU87695.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGATNVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSP
FWLGLIAIAACLGHIWPVFFGFKGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKP
QFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE
>SEQF1516_EDU87696.1 fructose-1,6-bisphosphatase, class II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALNDVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVDI
AVDPIEGTRMVAMGQSNALAVMAFAPRDSLLHAPDMYMKKLVVNRLAAGAIDLSLPLADNLRDVARALGKPLDKLRMVTL
DKPRLSAAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISACAVKALGGNMQAELIDFCQAKGDY
TENRQIAEQERKRCKAMGVDVNRVYSLDVLVRGNDILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSLY
>SEQF1516_EDU87697.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTLNQISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKSTLLRVMAGLLTPTAGTVMLQQQAMKNLKNRQRAAKIG
VLFQEAENQLFHSTVADEIAFGLKLQKCPADEITQRTHAALQCCQLADTASAHPLDLHSAQRRMVAVACLEALSPPLLLL
DEPSRDFDENWLSVFESWLEKCRQRGTSVVAISHDAAFTRRHFSRVVRLEDGLIRNINPPDDIHP
>SEQF1516_EDU87698.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKQWIVGTALLMLMTGNVWADGEPPTENILKDQFKKQYHGILKLDAITLKNLDAKGNQATWSAEGDVSSSDDLYTWVGQ
LADYELLEQTWTKDKPVKFSAMLTSKGTPASGWTVNFYSFQATASDRGRVVDDIKTNNKYLIVNSEDFNYRFSQLETALN
TQKNSIPALEKEVKALDKQMVAAQKAADAYWGKDANGKQMTREDAFKKIHQQRDEFNKQNDSEAFAVKYDKEVYQPAIAA
CHKQSEECYEVPIQQKRDFDINEQRRQTFLQSQKLSRKLQDDWITLEKGQYPLTMKVSEINSKKVAILMKIDDINQANER
WKKDTEQLRRNGVIK
>SEQF1516_EDU87699.1 transketolase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGY
DLPMEELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDGHDAASIKRAVEEARAVTDKPSL
LMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQLGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYAKAYPQ
EAAEFTRRMKGEMPSDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSGSKAINEDA
AGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAALMKQRQVMVYTHDSIGLGEDGPTHQPVEQVA
SLRVTPNMSTWRPCDQVESAVAWKYGVERQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPELIFIATGSE
VELAVAAYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWYKYVGLNGAIIGMTTFGESAP
AELLFEEFGFTVDNVVAKAKELL
>SEQF1516_EDU87700.1 lytic transglycosylase PilT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRSPKVKFLTIFTLSILITKMSFASSACFNEAGTMFRIEPNLIKAIALVESNLKKDSIGKNRDKKNNIKSFDYGLMQINQ
MHIPMLKKRGIIKDERDLLDNPCLNIKIGTEILYKHFSRCGMTWQCLGTYNAGFAMDNQKKRLQYAKKIYIVYTRLNELD
NRKALAK
>SEQF1516_EDU87701.1 16S rRNA methyltransferase RsmE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFDGSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHI
HLGQVMSRGEKMEFTIQKSIELGVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWC
AEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLGPRVLRTETTALTAITALQVRFG
DLG
>SEQF1516_EDU87702.1 putative selenate reductase, FAD-binding subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEQFFRPDSVEQALELKRRYQDEAVWFAGGSKLNATPTRTDKKIAISLQDLELDWVDWDNGALRIGAMSRLQPLRDARF
IPAALREALGFVYSRHVRNQSTIGGEIAARQEESVLLPVLLALDAELVFGNGETLSIEDYLACPCDRLLTEIIIKDPYRT
CATRKISRSQAGLTVVTAAVAMTDHDGMRIALDGVASKALRLHDVEKQNLEGNALEQAVANAIFPQEDLRGSVAYKRYIT
GVLVADLYADCQQAGEEAV
>SEQF1516_EDU87703.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPNIFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYEN
FVSQLDISENKEKLNWLGKMDATSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLT
RHNH
>SEQF1516_EDU87704.1 DNA topoisomerase IV, A subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDS
ACYEAMVLMAQPFSYRYPLVDGQGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR
LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTEAEIITSRAEIRKIYENGRGSVR
MRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRNKKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTD
LEKSYRINLNMIGLDGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEIIRNEDEPK
PALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGILASERKMNNLLKKELQADAQAYGDDRRSPL
QEREEAKAMSEHDMLPSEPVTIVLSQMGWVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITL
PSARGQGEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITLPENAHVMPPVVIEDAS
DMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARGEDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGE
RGRRGTLMRGLQRIDRVEIDSPRRASSGDSEE
>SEQF1516_EDU87705.1 2-acyl-glycerophospho-ethanolamine acyltransferase/acyl-acyl-carrier protein synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLFSFFRNLCRVLYRVRVTGDPQALKGERVLITPNHVSFIDGILLGLFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLD
PTQPMAIKHLVRLVEQGRPVVIFPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQI
TLHILPPTQVEMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFGAGKKCVEDVNFTPDSYRKLLTK
TLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAIARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWH
LPEQLTQVRWVYLEDLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILANVEQIKTI
ADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPELVYDRSCTVLFGTSTFLGHYARFANPYDFYR
LRYVVAGAEKLQESTKQLWQDKFGLRILEGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKG
PNIMNGYLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMVSLEMVEQLALGVSPDK
VHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPELAVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEVEQHDE
>SEQF1516_EDU87706.1 aspartate racemase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVDFHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIV
LCTNTMHKVADAIESRCTLPFLHIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADERAKINQI
IFEELCLGQFTEASRAYYAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAAIHAEDAVAFMLS
>SEQF1516_EDU87707.1 DNA topoisomerase IV, B subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSVDEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHP
EEGVPAVELILCRLHAGGKFSNKNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGNCGKRN
TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDGLNDYLAEAVNGLPTLPEKPFIG
NFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQGGTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVL
SVKMQDPQFAGQTKERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQRRMRAAKKVVRKKLTSGPALPGK
LADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEVSSDEVLASQEVHDISVAIGIDPDSDDLSQL
RYGKICILADADSDGLHIATLLCALFVKHFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNV
QRFKGLGEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGDMAEIEV
>SEQF1516_EDU87708.1 IS66 family transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISLPSGTRIWLVAGVTDMCKSFNGLGEQVQHVLNDNPFSGHLFIFRGRRGDTVKILWADADGLCLFTKRLEEGQFIWPA
VRDGKVSITRSQLAMLLDKLDWRQPKTSRLNALTML
>SEQF1516_EDU87709.1 bifunctional protein HldE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVTLPEFERAGVMVVGDVMLDRYWYGPSSRISPEAPVPVVKVNTIEERPGGAANVAMNIASLGANARLVGLTGIDDAAR
ALSKSLADVNVKCDFVSVPTHPTITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASV
QQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMKLIADYELSALLVTRSEQGMSLL
QPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAAGNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGF
GVMTEEELKLAVVAARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNPLEQRMIVL
GALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANGGEVLVLNFEDGCSTTNIIKKIQQDKKG
>SEQF1516_EDU87710.1 hypothetical protein ECH7EC4501_2115 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNFPENSLPIISDDLVDTNKEQLGYTAEEMPDDITFKR
>SEQF1516_EDU87711.1 glutathionylspermidine synthase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MERVSITERPDWREKAHEYGFNFHTMYGEPYWCEDAYYKLTLAQVEKLEEVTAELHQMCLKVVEKVIASDELMTKFRIPK
HTWSFVRQSWLTHQPSLYSRLDLAWDGTGEPKLLENNADTPTSLYEAAFFQWIWLEDQLNAGNLPEGSDQFNSLQEKLID
RFVELREQYGFQLLHLTCCRDTVEDRGTIQYLQDCATEAEIATEFLYIDDIGLGEKGQFTDLQDQVISNLFKLYPWEFML
REMFSTKLEDAGVRWLEPAWKSIISNKALLPLLWEMFPNHPNLLPAYFAEDDHPQMEKYVVKPIFSREGANVSIIENGKT
IEAAEGPYGEEGMIVQQFHPLPKFGDSYMLIGSWLVNDQPAGIGIREDRALITQDMSRFYPHIFVE
>SEQF1516_EDU87712.1 cystathionine beta-lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFESMEAKKHATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGC
ALFPCGAAAVANSILAFVEQGDHVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSIT
MEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCWEQLRENAYLM
GQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLN
DEELANYLDNFSLFSMAYSWGGYESLILANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFARIV
>SEQF1516_EDU87713.1 acetyl-CoA acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVPAYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVS
AITINDVCGSGLKALHLATQAIQCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMTQSNGQTLVVDTDEQPHTDASAEGLARLNPSFDSLGS
VTAGNASSINDGAAAVMMMSEAKARALNLPVLARIRAFASVGVDPALMGIAPVYATRRCLERVGWQLADVDLIEANEAFA
AQALSVGKMLEWDERRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERDE
>SEQF1516_EDU87714.1 chromosome initiation inhibitor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLENMFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEW
LGDEQTGSTPLLLSLAVNADSLATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLG
ALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPCHIVNSSEAFVQLARQGTTCCMI
PHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPESRMMRKVTDALLDYGHKVLRQD
>SEQF1516_EDU87715.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTIFTVGAVVLATCVLSGCVNEQKVNQLASNVQTLNAKIARLEQDMKALRPQIYAAKSEANRANTRLDAQDYFDCLRCL
RMYAE
>SEQF1516_EDU87716.1 L-sorbose 1-phosphate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTKVAAIYGKRDVRLREFELPEITDNELLVSVISDSVCLSTWKAALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKN
LTGKYKKGQRFVLQPAMGLPSGYSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQVQKLLPVELAASKGIELVYVNTK
GMSDPVQMLRALTGDAGFDDIFVYAAVSAVVEMADELLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTD
DMKEAIALSATGQLQPSFMVTHIGGLDAVPETVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKELARLVEET
HGIWNEQAEKYLLAQFGVDIGEAAQ
>SEQF1516_EDU87717.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANKTEKPTQKKLQDASKKGQILKSRDLTVSVIMLVGTLYLGYVFDVHHIMSILEYILDHNAKPDIWDYFKAMGIGWLKT
IIPFLLVCMFTTILVSWFQSKMQLATEAVKLKFDSLNPVNGLKRIFGLKTVKEFVKAILYIIFFALEIKVFWSNHKSLLF
KTLDGDIISLLSDWGEMLFLLILYCLGSMIIVLIFDFIAEYFLFMKDMKMDKQEVKREYKEQEGNPEIKSKRRERHQEIL
SEQLKSDVSNSRLMIANPTHIAIGIYFKPHLSPIPLISVRETNEVALAVRKYAKEIGIPIITDKKLARKIYATHRRYDYV
SFENIDEILRLLLWLEDVENAGQPVPDEQLSSEDKYIEGEDTKSENNDNNLKN
>SEQF1516_EDU87718.1 NADP(H)-dependent aldo-keto reductase Tas [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSRE
KLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDT
LDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGT
LTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLAPAQMALAFVRRQPFVASTLLGATTMDQLKTNIE
SLHLELSEDVLAEIEAVHQVYTYPAP
>SEQF1516_EDU87719.1 YecA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDSSWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQ
DDGFLFQLYLPDGDDVSVFDRADALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEE
IIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH
>SEQF1516_EDU87720.1 hydrogenase nickel insertion protein HypA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAVRFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVV
EVHQHDAQCPLCHGERLRVDTGDSLIVKSIEVE
>SEQF1516_EDU87721.1 inorganic anion transporter, sulfate permease (SulP) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLAMVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLL
MGLWANLPMAIGCAISLTAFTAFSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLL
LIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIAISIIGLIFDPAVKYHGLVAMPS
LTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVFDATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGA
APAAVYIESAAGTAAGGKTGLTATVVGALFLLILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFIDAMAGLVC
AVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYAGGWAI
>SEQF1516_EDU87722.1 type III secretion apparatus protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNELLSKVNRLIRRTAQSLAACEASLQKLNAEKEKLAEKERLYDMQLKNLQSLLDMKELLGEVVFRQDIFYSLRKVTVIQ
QQIAEINLEKQKIAERRKILNKEIVQQQAQRKHWWLKGEKYDRLKKRIKKQLLNQMLYQDELEQEEKYNGRSQEN
>SEQF1516_EDU87723.1 iron ABC transporter, permease protein FitD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVGLRPLRVGKFSTLVRPKNLVLLGGLFLFAVGILIFGLMHGSFFVPASEVGRALFAPENVSTDARYIVQDIRLPRVIM
ALLCGAMLGMAGAAMQSIARNGLADPGLIGVKEGCSVAVLWLIFQFPMLGMFWRPVAGLAGGLLVALIVIFCAREISRPR
FVLIGIGVSWFFAAGIGVFMTTADVRDVQTALMWLSGSLHAANWMLVGISACWMLPAALLLLFTARTADIALLGHQVATG
LGVNSSRLALLRVAAPIILTAVCVSCVGNIGFVGLIAPHISRFILRGGQTTLLLGSAVSGALLVILADSIGRLAFLPLQL
PAGIIISLIGGPFFLLLLWQRRNSF
>SEQF1516_EDU87724.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMTLPYPYSSSARFYALRLLPGQEVFSQLHAFAQQQQLHAAWIAGCTGSLTDIALRYAGQEGTTLLNGTFEVISLNGTLE
QSGEHLHLCVSDPHGTMLGGHMMPGCTVRTTLELVIGSLEELAFSRQPCALSGYDELHISPVK
>SEQF1516_EDU87725.1 dihydropyrimidinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFAMRVLIKNGTVVNADGQAKQDLLIESGIVRQLGNNISPQLPYEEIDATGCYVFPGGVDVHTHFNIDVGIARSCDDFF
TGTRAAACGGTTTIIDHMGFGPNGCRLRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTY
QYKLNDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAEAIARMINLAQIAGNAPLY
IVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYDTEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCT
FSMAQRLQISKGDFSRCPNGLPGVENRMQLLFSSGVMTGRITPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVVIIDP
RQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRFLRRKPFVPPVL
>SEQF1516_EDU87726.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVLWQSDLRVSWRAQWLSLLIHGLVAAVILLMPWPLSYTPLWMVLLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQ
EWSIVKAPWMIKSGMMLRLRSDSGKRQHLWLAADSMDEAEWRDLRRILLQQETQR
>SEQF1516_EDU87727.1 outer membrane invasion protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGSRLADNHTLSAGYAQSKVQDFKNIKGVNLQYRYEWDSPVSVVGSFSYMKGDWADSHRDEADDFYRHQADIKYYSFLA
GPAYRLNDYISFYGLVGISHTKAKGDYEWRNSVGADESDGYLSESVSKKSTDFAYAAGVIINPWGNMSVNVGYEGTKADI
YGKHSVNGFTVGVGYRF
>SEQF1516_EDU87728.1 guanine deaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGEHTLKAVRGSFIDVTRTVDNPEEIASALRFIEDGLLLIKQGKVEWFGEWEDGKHQIPDTIRVRDYRGKLIVPGFVDT
HIHYPQSEMVGAYGEQLLEWLNKHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINM
RMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQMAMAQRLKEEYPDTWVHTHLCEN
KDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHCVHLKEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVK
VGMGTDIGAGTTFNMLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEPTATPLQQL
RYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN
>SEQF1516_EDU87729.1 transcription activator effector binding domain/DNA gyrase inhibitor domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNLTLDVNIIDFPSIPVAMLPHRCRPELLNYSVAKFIMWRKETGLSPVNQSQTFGVAWDDPATTAPEAFRFDICGSVSE
PIPDNRYGVSNGELTGGRYAVARHVGELDDISHTIWGIIRHWLPASGEKMRKAPILFHYTNLAEGVTEQRLETNVYVPLA
>SEQF1516_EDU87730.1 putative regulatory protein for type III secretion apparatus [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIEEGLLLPMNVLLQGQKLTLLDPEMWFLRGNENKDVTLVITIGNNHQKLMVVEDILLLIDRSQIEVTAGKVIYHPLRID
ILSKLLAFIDESTGSVEREHHELFADALPFASEVVLFSKVASEAWFLATYLSSDNINEILFQHLRKTECYKLVRYLLSQS
LIHTSLYDLGELYGVSYSHFRRLCSYALGGKVKTELCGWRVARAVLEIIEGNSDMTTIAHKYGYSSSSHFSAEVKSRLGK
TPRELCKKL
>SEQF1516_EDU87731.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETVSLYQNADDCSAANPGKSAECTTAYNNALKEAERTAP
KYATREDCVAEFGEGQCQQAPAQAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKY
TDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSSRSMGG
>SEQF1516_EDU87732.1 carbamate kinase arcC homolog [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIVTHGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVAL
SQGYIGYDLQNALREELLSRGINKPVVTLVTQVEVDANDPAFLNPTKPIGSFFTEQEAEQLTKQGYTLKEDAGRGYRRVV
ASPKPVDIIEKETVKALVEAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLAEMIDADMLIILTAVEKVAINFG
KENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAAASFARSRAGREALITVLSKAKEGIEGKTGTVICQ
>SEQF1516_EDU87733.1 6-phospho-beta-glucosidase BglA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHGVPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLF
AEMGFKCFRTSIAWTRIFPKGDEAQPNEEGLKFYDSLFDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRF
AEVVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFVASALAVKAARRINLEMKVGC
MLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGYYPSYVLNEWERRGFNIKMEDSDLDVLREGTCDYLGFSYYMTN
AVKAEGGTGDAISGFEGSVPNPYVKASDWGWQIDPVGLRYALCELYERYQKPLFIVENGFGAYDKVEEDGSINDDYRIDY
LRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDDGTGDMSRSRKKSFNWYKEVIASNGENL
>SEQF1516_EDU87734.1 isopentenyl-diphosphate delta-isomerase, type 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQTEHVILLNAQGVPTGTLEKYAAHTADTRLHLAFSSWLFNAKGQLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAV
IRRCRYELGVEITPPESIYPDFRYRATDPNGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLHGIDATPWAFSP
WMVMQAANSEARKLLSAFAQHN
>SEQF1516_EDU87735.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINDLKSILLKSSEEVDVFIKIFESWVTKLPSISGPVNLHIPTSFKDKSLEVESYFVDKSIWNVHIAYHDDKRFVFFTDQ
FIAEFSPQEFVDNCEQYLINNHCFSPDKVNEICEQARHYLVEKMCETHSLAMNNSVLTNPEDS
>SEQF1516_EDU87736.1 2-octaprenyl-6-methoxyphenol hydroxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVIIVGGGMAGATLALAISRLSHGALPVHLIEATAPESHAHPGFDGRAIALAAGTCQQLARIGVWQSLADCATAITTVH
VSDRGHAGFVTLAAEDYQLAALGQVVELHNVGQRLFALLRKAPGVTLHCPDRVANVARTQSHVEVTLEGGETLTGRVLVA
ADGTHSALATVCGVDWQQEPYEQLAVIANVATSVAHEGRAFERFTQHGPLAMLPMSDGRCSLVWCHPLERREEVLSWSDE
KFCRELQSAFGWRLGKITHAGKRSAYPLALTHAARSITHRTVLVGNAAQTLHPIAGQGFNLGMRDVMSLAETLTQAQERG
EDMGDYGVLCRYQQRRQSDREATIGVTDSLVHLFANRWTPLVVGRNIGLMTMELFTPARDVLAQRTLGWVAR
>SEQF1516_EDU87737.1 transcriptional regulatory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLENKFSYHFLEGLTLTEDGILTQGNEQVYIPPKELGVLIVLLESAGHVVLKDMIIESVWKNIIVSDESLTRCIYSLRC
IFEKIGYDRCIETIYRKGYRFSGQVFKTKINEDNTSDYSIAIFPFTTSLKTLDPLILNQELVQIISNKKIDGLYTYPMAA
TNFCNDHISQNSFLRRFNPDYFVTGRINQNNAVNTLYIELTDAKNLFLIASNHLPVDELHNTSQFIIENILQTVHNPQRS
VRLTKQDQGYKNHYLSDEMLAGKKELYEFTPESIYRAMTIFDGLQNKSDIQTLKTECYCLLAECHMSLALHGKSELELAA
QKALELLDYVSDITTVDGKILAIMGLITGLSGQAKVSHILFEQAKIHSTDIASLYYYRALVNFHNEKIEEARICIDKSLQ
LEPRRRKAVVIKECVDMYVPNPLKKNMKLYYKETESGSHRVIIDNILKLKQLTRICMR
>SEQF1516_EDU87738.1 ornithine decarboxylase, constitutive [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSMNIAASSELVSRLSTHRRVVALGDTDFTDVAAVVITAADSRSGILTLLKRTGFHLPVFLYSEHAVELPAGVTAVING
NEQQWLELESAACQYEENLLPPFYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENIFRADMCNADVKLGD
LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPVYLEASRNP
FGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPFRLAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIP
MMADSSPLLLELNENDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDVN
AKIHEGESGRRLWAECVELGIESRKAILARCKLFRPFIPPVVDGKLWQDYPTSVLASDRRFFSFEPGAKWHGFEGYAADQ
YFVDPCKLLLTTPGIDAETGEYSDFGVPATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIED
DSPLAEVLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAHSAYIRGDVELVRIRDA
EGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNLLPGFSPELQGVYSETDADGMKRLYGYVLK
>SEQF1516_EDU87739.1 diaminopimelate decarboxylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALKQFDVVRFAQKACSNIHILRLMREQGVKVDSVSLGEI
ERALAAGYNPQTHPDDIVFTADVIDQATLERVSELQIPVNAGSVDMFDQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGE
NSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVIEFGQDLQAISAGGGLSIPYQQGEEAVD
TEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQSGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISAL
AADGRSLEHAPTVETVVAGPLCESGDVFTQQEGGNVEPRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLLPEVLFDNG
QARLIRRRQTIEELLALELL
>SEQF1516_EDU87740.1 glycine cleavage system H protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVDLPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVA
VNDALSDSPELVNSEPYAGGWIFKIKASDESELESLLDATAYEALLEDE
>SEQF1516_EDU87741.1 probable low-affinity inorganic phosphate transporter 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNLFVGLDIYTGLLLLLALAFVLFYEAINGFHDTANAVATVIYTRAMQPQLAVVMAAFFNFFGVLLGGLSVAYAIVHML
PTDLLLNMGSTHGLAMVFSMLLAAIIWNLGTWFFGLPASSSHTLIGAIIGIGLTNALLTGSSVMDALNLREVTKIFSSLI
VSPIVGLVIAGGLIFLLRRYWSGTKKRDRIHRIPEDRKKKKGKRKPPFWTRIALIVSAAGVAFSHGANDGQKGIGLVMLV
LVGIAPAGFVVNMNASGYEITRTRDAVTNFEHYLQQHPELPQKLIAMEPPLPAASTDGAQVTEFHCHPGNTFDAIARVKT
MLPGNMESYEPLSVSQRSQLRRIMLCISDTSAKLAKLPGVSKEDQNLLKKLRSDMLSTIEYAPVWIIMAVALALGIGTMI
GWRRVAMTIGEKPFLISYCVPPGGEPAFPVRGYVAGLE
>SEQF1516_EDU87742.1 quinol monooxygenase YgiN [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTVIAEIRTRPGQHHRQAVLDQFAKIVPTVLKEEGCHGYAPMVDCAAGVSFQSMAPDSIVMIEQWESIAHLEAHLQTPH
MKAYSEAVKGDVLEMNIRILQPGI
>SEQF1516_EDU87743.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKKPVAQLERQHSLLENPCAYGLLSQFQAAIVVNCFTLNKII
>SEQF1516_EDU87744.1 glycine cleavage system T protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHEVRTDAGMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKS
GKALYSGMLNASGGVIDDLIVYYFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLF
NDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEGGVKPCGLGARDTLRLEAGMNLYGQEM
DETISPLAANMGWTIAWEPADRDFIGREALEVQREHGTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPT
LGYSIALARVPKGIGETAIVQIRNREMPVKVTKPVFVRNGKAVA
>SEQF1516_EDU87745.1 nucleoside permease NupG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVYSSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGA
ITLFMAAQVTTPEAMFLVILINSFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
QLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSMLLGAELQITNMFGNTFLHSFDK
DPMFASSFIVQHASIIMSISQISETLFILTIPFFLSRYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGC
AFDFFNISGSVFVEKEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSVVLAFAFMA
MFKYKHVRVPTGTQTVSH
>SEQF1516_EDU87746.1 2,5-didehydrogluconate reductase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANPTVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRSFDTAAAYKNEEGVGKALKNASVNREELFITTKLWND
DHNRPREALLDSLKKLQLDYIDLYLMHWPVPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQ
IELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYGKTPAQIVIRWHLDSGLVVIPKSVTPSRIAE
NFDVWDFRLDKDELGEIAKLDQGKRLGPDPDQFGG
>SEQF1516_EDU87747.1 hypothetical protein ECH7EC4501_1949 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTMLIYIKFYVATLKPHFNHHDKYKINIYLCRKYQYT
>SEQF1516_EDU87748.1 zinc transporter ZupT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIMLLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFG
LDRMLPHAHPQDLMQKSVQPLPKSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
YAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVDELMPLAKEIDPNNNPSYGVLCG
MSVMGFSLVLLQTAGIG
>SEQF1516_EDU87749.1 putative xanthine permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPPQFLSLTPLPRKNWHSTSMCLDSFINVNGCFLLWRAKGETLMSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQH
VLVMYAGAVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFAAVTPMIAIGMNPDIG
LLGIFGATIAAGFITTLLAQLIGRLMPLFPPLVTGVVITSIGLSIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILL
ITRYAKGFMSNVAVLLGIVFGFLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFLA
LGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVCISSGIILILFGMVPKMAVLVASI
PQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYNLYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVV
LNVFFNGYQHHADLVKESVSDKDLKVRTVRMWLLMRKLKKNEHGE
>SEQF1516_EDU87750.1 protein aegA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQMNKFIAAEAAECIGCHACEIACAVAHNQENWPLSHSDFRPRIHVVGKGLAANPVACHHCNNAPCVTACPVNALTFQSD
SVQLDEQKCIGCKRCAIACPFGVVEMVDTIAQKCDLCNQRSSGTQACIEVCPTQALRLMDDKGLQQIKVARQRKTAAGKA
SSDAQPSRSAALLPVNSRKGADKISASERKNHFGEIYCGLDPQQATYESDRCVYCAEKANCNWHCPLHNAIPDYIRLVQE
GKIIEAAELCHQTSSLPEICGRVCPQDRLCEGACTLKDHSGAVSIGNLERYITDTALAMGWRPDVSKVVPRIEKVAVIGA
GPAGLGCADILARAGVQVDVFDRHPEIGGMLTFGIPPFKLDKTVLSQRREIFTAMGIDFHLNCEIGRDITFSDLTSEYDA
VFIGVGTYGMMRADLPHEDAPGVIQALPFLTAHTRQLMGLPESEEYPLTDVEGKRVVVLGGGDTTMDCLRTSIRLNAASV
TCAYRRDEVSMPGSRKEVVNAREEGVEFQFNVQPQYIACDEDGRLTAVGLIRTAMGEPGPDGRRRPRPVAGSEFELPADV
LIMAFGFQAHAMPWLQGSGIKLDKWGLIQTGDVGYLPTQTHLKKVFAGGDAVHGADLVVTAMAAGRQAARDMLTLFDTKA
S
>SEQF1516_EDU87751.1 tetratricopeptide repeat protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDTETIEIFNNSDEWANQLKHALSKGENLALLHGLTPDILDRIYAYAFDYHEKGNVTDAEIYYKLLCIYAFENHEYLKGF
ASVCQSKKKYQQAYDLYKLSYNYSPYDDYSVIYRMGQCQIGAKNIDNAMQCFYHIINNCEDASVKSKAQAYIELLTDNSE
DNG
>SEQF1516_EDU87752.1 type III secretion apparatus protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFNKVLVGLRSHPELIILGLMVMIIAMLIIPLPTYLIDFLIGLNLTLAILVFLGSFYVDRILSFSSFPSILLITTLFRLA
LAISTSRLILLEADAGEIITSFGEFVIGDSLVVGFVIFSIVTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLR
AGIIDADLAKERRSVLERESQLYGSFDGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQNGMDFSTALTVYTILTVGDGLV
SQIPALLIAISAGFIVTRVNGDRDNMGQNIMSQLLSNSFVIVVTCVLALSIGLLPGFPLLVFLCLAVILGIYFYFKFKKK
GTEETVVEGDITVGLEPYNQDDDISLGIINKLDQVITETVPLVLIMNSVQAKKYTEINLADRIRSQFFIEYGIRIPGIVI
REGEGLNDEDVILMLNEVRASQFKIYHDLVLLVEYSDEVVSTLIKKPVIVNSNGEQYYWVTKSDAQKLTKIGCYTRTAMD
EMYNHLSVCLAHNINEYFGIQETKYILDQLEMKYSDLLKEILRYITVQRISEVIQRLIQERISVRNMRLVMEALALWSPR
EKDIITLVEHVRGALGRYICHKFSYSGEIKAIVISPEIEDRIRDGVRPTAGGTFLNLDASEAEMILDNFKLALSGINIPI
KDIILLGSVDIRRFIKKLIESSYRDLEVLSYGELTENVPVNILKTI
>SEQF1516_EDU87753.1 endonuclease I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYRYLSIAAVVLSAAFSGPALAEGINSFSQAKAAAVKVHADAPGTFYCGCKINWQGKKGVVDLQSCGYQVRKNENRASRV
EWEHVVPAWQFGHQRQCWQDGGRKNCAKDPVYRKMESDMHNLQPSVGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKEK
AAEPPARARGAIARTYFYMRDHYNLTLSRQQTQLFNAWDKMYPVTDWECERDERIAKVQGNHNPYVQRACQARKS
>SEQF1516_EDU87754.1 acetyl-CoA hydrolase/transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METQWTRMTADEAAEIIQHNDMVAFSGFTPAGSPKALPTAIARRANEQHEAKKPYQIRLLTGASISAAADDVLSDADAVS
WRAPYQTSSGLRKKINQGAVSFVDLHLSEVAQMVNYGFFGDIDVAVIEASALAPDGRVWLTSGIGNAPTWLLRAKKVIIE
LNHYHDPRVAELADIVIPGAPPRRNSVSIFHAMDRVGTRYVQIDPKKIVAVVETNLPDAGNMLDKQNPMCQQIADNVVTF
LLQEMAHGRIPPEFLPLQSGVGNINNAVMARLGENPEIPPFMMYSEVLQESVVHLLETGKISGASASSLTISADSLRKIY
DNMDYFASRIVLRPQEISNNPEIIRRLGVIALNVGLEFDIYGHANSTHVAGVDLMNGIGGSGDFERNAYLSIFMAPSIAK
EGKISTVVPMCSHVDHNEHSVKVIITEQGIADLRGLSPLQRARTIIDNCAHPMYRDYLHRYLENAPGGHIHHDLSHVFDL
HRNLIATGSMLG
>SEQF1516_EDU87755.1 sensor histidine kinase QseC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELFDTQLMLFAKRLSTLDLNEINAADRMAQTPNKLKHGH
VDDDALTFAIFTHDGRMVLNDGDNGEDIPYSYQREGFADGQLVGDKDQWRFVWMTSPDGKYRIVVGQEWEYREDMALAIV
AGQLIPWLVALPVMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRPLVESLNQLFARTHAMMVRERRF
TSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKALLQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSS
VMDIYHTAQQAKIDVRLTLNVQGIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVVDVTLNADNFIVRDNGPGVTPEALARI
GERFYRPPGQTATGSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEAKVSW
>SEQF1516_EDU87756.1 1-acyl-sn-glycerol-3-phosphate acyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGRLAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMV
TASNIVQPPTVTVGKKSLLWIPFFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFK
TGAFHAAIAAGVPIIPVCVSTTSNKINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELAAHCRSIMEQKIAELDKEVAERE
AAGKV
>SEQF1516_EDU87757.1 L-asparaginase 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATKSNYTAGKVGVENLVNAVPQLKDIANVKGEQVVNIGS
QDMNDDVWLTLAKKINTDCDKTDGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAAD
KASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARKHTSDTPFDVSKLNELPKVGIVY
NYANASDLPAKALVDAGYDGIVSAGVGNGNLYKSVFDTLATAAKNGTAVVRSSRVPTGATTQDAEVDDAKYGFIASGTLN
PQKARVLLQLALTQTKDPQQIQQIFNQY
>SEQF1516_EDU87758.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPEESPRLQYCANSCFCMWTEESSYFNRGVVEGILTKNHNARLSGYIFVDFSVSFLRLFLEKDWIDYLASTDMGIVLVSD
RNMQSLANYWRKHNSAISAVIYNDDGLDVANEKIRQLFIGRYLSFTRGNTLTQMEFTIMGYMVSGYNPYQIAEVLDMDIR
SIYAYKQRIEKRMGGKINELFIRSHSVQH
>SEQF1516_EDU87759.1 mannitol operon repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATLSEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVDNDEESVEYAVKPLLAQSGPLDDIDVALRLIYALGKM
DKWLYADITHFSQYWHYLKEQDETLGFADDMTWDFISNVNSITCNATLYDALKAMKFADFAVWSEARFSGMVKTALTLAV
TTTLKELTP
>SEQF1516_EDU87760.1 oxidoreductase, short chain dehydrogenase/reductase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGSGRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISY
LPVEEEDAQDVKKIIEECGRKAVLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWTALQISG
GQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQESSYVTAEVHGVCGGEHLG
>SEQF1516_EDU87761.1 integral membrane protein, TerC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQRAHARRLGLAGAMVMRLALLASIAWVTRLTNPLFTI
FSQEISARDLILLLGGLFLIWKASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAA
VVIAVGVMMFAARSIGDFVERHPSVKMLALSFLILVGFTLILESFDIHVPKGYIYFAMFFSIAVESLNLIRNKKNPL
>SEQF1516_EDU87762.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNCLMRYAYHAYKDARSSRRDKAFTPHPAWKTRTLLSIWGQQMLA
>SEQF1516_EDU87763.1 aromatic ring-opening dioxygenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPLVKDIIMSSTRMPALFLGHGSPMNVLEDNLYTRSWQTLGMTLPRPQAIVVVSAHWFTRGTGVTAMETPPTIHDFGGF
PQALYDTHYPAPGSPALAQRLVELLAPIPVTLDKEAWGFDHGSWGVLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLA
ALRDEGIMLVASGNVVHNLRTVKWHGDSSPYPWAMSFNEYVKANLTWQGPVEQHPLVNYLDHEGGALSNPTPEHYLPLLY
VLGAWDGQEPITIPVDGIEMGSLSMLSVQIG
>SEQF1516_EDU87764.1 thiol:disulfide interchange protein DsbC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKGFMLFTLLAAFSGFAQADDAAIQQTLAKMGIKSSDIQPAPVAGMKTVLTNSGVLYITDDGKHIIQGPMYDVSGTAPV
NVTNKMLLKQLNALEKEMIVYKAPQEKHVITVFTDITCGYCHKLHEQMADYNALGITVRYLAFPRQGLDSDAEKEMKAIW
CAKDKNKAFDDVMAGKSVAPASCDVDIADHYALGVQLGVSGTPAVVLSNGTLVPGYQPPKEMKEFLDEHQKMTSGK
>SEQF1516_EDU87765.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVDGQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIK
IINPQQIPPEVAALIN
>SEQF1516_EDU87766.1 HTH-type transcriptional activator TtdR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQILENTLATTLLNRSARGVALTESGQRCYEHALEILTQY
QRLVDDVTQIKTRPEGMIRIGCSFGFGRSHIAPAITELMRNYPELQVYFELFDRQIDLVQDNIDLDIRINDEIPDYYIAH
LLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVKVSGHLSSNSGEIVLQWALEGKG
IMLRSEWDVLPFLESGKLVQVLPEYAQSANIWAVYREPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM
>SEQF1516_EDU87767.1 oxidoreductase, pyridine nucleotide-disulfide family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGDIMRPIPFEELLTRIFDEYQQQRSIFGIPEQQFYSPVKGKTVSVFGETCATPVGPAAGPHTQLAQNIVTSWLTGGRFI
ELKTVQILDRLELEKPCIDAEDECFNTEWSTEFTLLKAWDEYLKAWFALHLLEAMFQPSDSGKSFIFNMSVGYNLEGIKQ
PPMQQFIDNMMDASDHPKFAQYRDTLNKLLQDDAFLARHGLQEKRESLQALPARIPTSMVHGVTLSTMHGCPPHEIEAIC
RYMLEEKGLNTFVKLNPTLLGYARVREILDVCGFGYIGLKEESFDHDLKLTQALEMLERLMALAKEKSLGFGVKLTNTLG
TINNKGALPGEEMYMSGRALFPLSINVAAVLSRAFDGKLPISYSGGASQLTIRDIFDTGIRPITMATDLLKPGGYLRLSA
CMRELEGSDAWGLDHVDVERLNRLAADALTMEYTQKHWKPEERIEVAEDLPLTDCYVAPCVTACAIKQDIPEYIRLLGEH
RYADALELIYQRNALPAITGHICDHQCQYNCTRLDYDSALNIRELKKVALEKGWDEYKQRWHKPAGSGSRHPVAVIGAGP
AGLAAGYFLARAGHPVTLFEREANAGGVVKNIIPQFRIPAELIQHDIDFVAAHGVKFEYGCSPDLTVEQLKNQDFHYVLI
ATGTDKNSGVKLAGDNQNVLKSLPFLREYNKGTALKLGKHVVVVGAGNTAMDCARAALRVPGVEKATVVYRRSLQEMPAW
REEYEEALHDGVEFRFLNNPERFDADGTLTLRVMSLGEPDEKGRRRPVETNETVTLHVDSLITAIGEQQDTEALNAMGVP
LDKNGWPDVDHNGETRLTDVFMIGDVQRGPSSIVAAVGTARRATDAILSRENIRSHQNDKYWNNVNPAEIYQRKGDISIT
LVNSDDRDAFVAQEAARCLECNYVCSKCVDVCPNRANVSIAVPGFQNRFQTLHLDAYCNECGNCAQFCPWNGKPYKDKIT
VFSLAQDFDNSSNPGFLVEDCRVRVRLNNQSWVLNIDSEGQFNNVPPELNDMCRIISHVHQHHHYLLGRVEV
>SEQF1516_EDU87768.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQYRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRL
YHDAMVAEVCSSQQIFRFKARYDYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY
>SEQF1516_EDU87769.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNFTVVQYQILSQFQIEHIQLFKEQFFIKLNKLFPQCSVKMLTYGIYFRRIEISPYEPDGGFL
>SEQF1516_EDU87770.1 ISSfl4 ORF3 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNTLPDNIEQLKALLIAQQAVIVRLSGEITGYAREISSLRALVAKLQRMLFGRSSEKSREKIEKKIARAETRITELQNR
LGEAQLQLTSMAGETAPKTSDSPVRKALPATLPRDRQVISPAETECPVCSGKLKPLGESISEQLDIINTAFRVIETVRPK
RACSRCDCIVQAPQPPKPIERSYASPALLARIIMAKFAEHLPLYRQSEIYARQGVELHRNTMGRWVDIMGEQLRPLYDEL
KHYVLMPGKVHADDTPVNVLEPGQGKTRTGRLWVYVRDDRNAGSTMPAAVWFSYSPDRKGIHPQQHLADYRGILQADAYA
GYNALYESGQATEAACMAHARRKIHDVHVRHPTTVTGEALRRIGELYAIEAEIRGSPAEERLAVRKARTVPLMQSLYEWL
QGQMNTLSRHSDTAKAFTYLLKQWDALNEYCRNGWVEIDNNLCENALRVVALGRRNYRTWFLPGKGNGTKESWFFRNRPH
HE
>SEQF1516_EDU87771.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKERTRVTNTEQLVFIAALNISYELAQEKAKTRDYAASME
QRIRMLQQTIEQALLEQGRITEKTNQNFE
>SEQF1516_EDU87772.1 hydrogenase-2, large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEIVKNRDPRDAWMIVQRICGVCTTTHALSSVRAAESAL
NIDVPVNAQYIRNIILAAHTTHDHIVHFYQLSALDWVDITSALQADPTKASEMLKGVSTWHLNSPEEFTKVQNKIKDLVA
SGQLGIFANGYWGHPAMKLPPEVNLIAVAHYLQALECQRDANRVVALLGGKTPHIQNLAVGGVANPINLDGLGVLNLERL
MYIKSFIDKLSDFVEQVYKVDTAVIAAFYPEWLTRGKGAVNYLSVPEFPTDSKNGSFLFPGGYIENADLSSYRPITSHSD
EYLIKGIQESAKHSWYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLVKLAAGRESTQNKLNE
IVAIYQKLTGNTLEVAQLHSTLGRIIGRTVHCCELQDILQNQYSALITNIGKGDHTTFVKPNIPATGEFKGVGFLEAPRG
MLSHWMVIKDGIISNYQAVVPSTWNSGPRNFNDDVGPYEQSLVGTPVADPNKPLEVVRTIHSFDPCMACAVHVVDADGNE
VVSVKVL
>SEQF1516_EDU87773.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRFEDDGYFCTIEVTATSTVTLDTLTEKHAEQENMTLTE
LKKVIADIYPGQTQFYVIEFKCL
>SEQF1516_EDU87774.1 putative xanthine dehydrogenase accessory factor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIFTEAAKLEEQNCPFAMAQIIDSRGSTPRHSAQMLVRADGSIVGTIGGGMVERKVIEESLQALQERKPRLFHGRMARN
GADAVGSDCGGAMSVFISVHGMRPRLVLIGAGHVNRAIAQSAALLGFDIAVADIYRESLNPELFPPSTTLLHAESFGAAV
EALDIRPDNFVLIATNNQDREALDKLIEQPIAWLGLLASRRKVQLFLRQLREKGVAEEHIARLHAPVGYNIGAETPQEIA
ISVLAEILQVKNNAPGGLMMKPSHPSGHQLVVIRGAGDIASGVALRLYHAGFKVIMLEVEKPTVIRCTVAFAQAVFDGEM
TVEGVTARLATSSAEAMKLTERGFIPVMVDPACSLLDELKPLCVVDAILAKQNLGTRADMAPVTIALGPGFAAGKDCHAV
IETNRGHWLGQVIYCGCAQENTGVPGNIMGHTTRRVIRAPAAGIMRSNVKLGDLVKEGDVIAWIGEHEIKAPLTGMVRGL
LNDGLAVVGGFKIGDIDPRGETADFTSVSDKARAIGGGVLEALMMLMHQGVKATKEVLEVA
>SEQF1516_EDU87775.1 putative hypoxanthine oxidase XdhD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIHFTLNGAPQELTVNPGENVQKLLFNMGMHSVRNSDDGFGFAGSDAIIFNGNIVNASLLIAAQLEKADIRTAESLGKW
NELSLVQQAMVDVGVVQSGYNDPAAALIITDLLDRIAAPTREEIDDALSGLFSRDAGWQQYYQVIELAVARKNNPQATID
IAPTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDRVTADACVIKMLRSPHAHALITHLDVSKAEALPGVVHVITHLNCPD
IYYTPGGQSAPEPSPLDRRMFGKKMRHVGDRVAAVVAESEEIALEALKLIEVEYEVLKPVMSIDEAMAEDAPVVHDEPVV
YVAGAPDTLEDDNSHAAQRGEHMIINFPIGSRPRKNIAASIHGHIGDMDKGFADADVIIERTYNSTQAQQCPTETHICFT
RMDGDRLVIHASTQVPWHLRRQVARLVDMKQHKVHVIKERVGGGFGSKQDILLEEVCAWATCVTGRPVLFRYTREEEFIA
NTSRHVAKVTVKLGAKKDGRLTAVKMDFRANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYG
APKGNFAITMALAELAEQLQIDQLEIIERNRVHEGQELKILGAIGEGKAPTSVPSAASCALEEILRQGREMIQWSSPKPQ
NGDWHIGRGVAIIMQKSGIPDIDQANCMIKLESDGTFIVHSGGADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHAL
FDKGAYASSGTCFSGNAARLAAENLREKILFHGAQMLGEPVADVQLATPGVVRGKKGEVSFGDIAHKGETGTGFGSLVGT
GSYITPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALGQIYGATLRAIGHSMSEEIIYDAEGHPLTRD
LRSYGAPKIGDIPRDFRAVLVPSDDKVGPFGAKSISEIGVNGAAPAIATAIHDACGIWLREWHFTPEKILTALEKI
>SEQF1516_EDU87776.1 glutamate-ammonia ligase adenylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPLSSPLQQYWQTIVERLPEPLAEESLSAQAKSVLTFSDFVQDSISAHPEWLTELESQPPQADEWQHYVAWLQEALINV
SDEAGLMRELRLFRRRIMVRIAWAQTLALVTEESILQQLSYLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGM
GKLGGGELNFSSDIDLIFAWPEHGCTQGGRWELDNAQFFTRMGQRLIKVLDQPTQDGFVYRVDMRLRPFGESGPLVLSFA
ALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELRAMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGA
GGIREIEFIVQVFQLIRGGREPSLQSRSLLPTLSVIAALHLLSENDAEQLRVAYLFLRRLENLLQSINDEQTQTLPSDEL
NRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSEQWRELWQDALQEDDTTPVLAHLSEDDRKQV
LTLIADFRKELDKRTIGPRGRQVLDHLMPHLLSDVCAREDAAVTLLRITALLAGIVTRTTYLELLSEFPAALKHLISLCA
ASPMIASQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQLLRIAAADIAGTLPVM
KVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRGFAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGER
EIDGRQFYLRLAQRIMHLFSTRTSSGILYEVDARLRPSGAAGMLVTSTEAFADYQKNEAWTWEHQALVRARVVYGDPQLT
AHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIEFITQYLVLRYAHEKPKLTRWSDNV
RILELLAQNDIMEEQEAMALTRAYTTLRDELHHLALQELPGHVPEDCFTAERELVRASWQKWLVEE
>SEQF1516_EDU87777.1 TPR repeat protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRN
RERGPVAI
>SEQF1516_EDU87778.1 ISSfl4 ORF3 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTTDDYCTVRDSVLQADAYAGFNELYRNGGITEAACWAHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAE
QRLAERQRKTKPLLKSLESWLREKMKTLSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKNFLF
FGSDHGGERGALLYSLIGMCKLNDVDPESYLRHVLGVIADWPVNRVSELLPWRIALPAE
>SEQF1516_EDU87779.1 methylmalonyl-CoA mutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNEQEWQQLANKELSRREKTVDSLVQQTAEGIAIKPLYTEADLDNLEVTGTLPGLPPYVRGPRATMYTAQPWTIRQYAG
FSTAKESNAFYRRNLAAGQKGLSVAFDLATHRGYDSDNPRVAGDVGKTGVAIDTVEDMKVLFDQIPLDKMSVSMTMNGAV
LPVLAFYIIAAEEQGVTPDKLTGTIQNDILKEYLCRNTYIYPPKPSMRIIADIIAWCSGNMPRFNTISISGYHMGEAGAN
CVQQVAFTLADGIEYIKAAISAGLKIDDFAPRLSFFFGIGMDLFMNVAMLRAARYLWSEAVSGFGAQDPKSLALRTHCQT
SGWSLTEQDPYNNVIRTTIEALAATLGGTQSLHTNAFDEALGLPTDFSARIARNTQIIIQEESELCRTVDPLAGSYYIES
LTDQIVKQARAIIQQIDEAGGMAKAIEAGLPKRMIEEASAREQSLIDQGKRVIVGVNKYKLDHEDETDVLEIDNVMVRNE
QIASLERIRATRDDAAVTAALNALTHAAQHNENLLAAAVNAARVRATLGEISDALEAAFDRYLVPSQCVTGVIAQSYHQS
EKSASEFDAIVAQTEQFLADNGRRPRILIAKMGLDGHDRGAKVIASAYSDLGFDVDLSPMFSTPEEIARLAVENDVHVVG
ASSLAAGHKTLIPELVEALKKWGREDICVVAGGVIPPQDYAFLQERGVAAIYGPGTPMLDSVRDVLNLISQHHD
>SEQF1516_EDU87780.1 agmatinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMR
ERLNVVDCGDLVYAFGDAREMSEKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
FDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQIVGDMPVYLTFDIDCLDPAFAP
GTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKKGE
>SEQF1516_EDU87781.1 NleB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSSLNVLQSSFRGKTALSNSTLLQKVSFAGKEYPLEPIDEKTPILFQWFEARPERYEKGEVPILNTKEHPYLSNIINAA
KIENERIIGVLVDGNFTYEQKKEFLSLENEYQNIKIIYRADVDFSMYDKKLSDIYLENIHKQESYPASERDNYLLGLLRE
ELKNIPEGKDSLIESYAEKREHTWFDFFRNLAMLKAGSLFTETGKTGCHNISPCSGCIYLDADMIITDKLGVLYAPDGIA
VHVDCNDEIKSLENGAIVVNRSNHPALLAGLDIMKSKVDAHPYYDGLGKGIKRHFNYSSLHDYNAFCDFIEFKHENIIPN
TSMYTCSSW
>SEQF1516_EDU87782.1 M20/DapE family protein YgeY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNIPFKLILEKAKDYQADMTRFLRDMVAIPSESCDEKRVVHRIKEEMEKVGFDKVEIDPMGNVLGYIGHGPRLVAMDA
HIDTVGIGNIKNWDFDPYEGMETDELIGGRGTSDQEGGMASMVYAGKIIKDLGLEDEYTLLVTGTVQEEDCDGLCWQYII
EQSGIRPEFVVSTEPTDCQVYRGQRGRMEIRIDVQGVSCHGSAPERGDNAIFKMGPILGELQELSQRLGYDEFLGKGTLT
VSEIFFTSPSRCAVADSCAVSIDRRLTWGETWEGALDEIRALPAVQKANAVVSMYNYDRPSWTGLVYPTECYFPTWKVEE
DHFTVKALVNAYEGLFGKAPVVDKWTFSTNGVSIMGRHGIPVIGFGPGKEPEAHAPNEKTWKSHLVTCAAMYAAIPLSWL
ATE
>SEQF1516_EDU87783.1 YGGT family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTLTFLLSTVIELYTMVLLLRIWMQWAHCDFYNPFSQFVVKVTQPIIGPLRRVIPAMGPIDSASLLVAYILSFIKAIVL
FKVVTFLPIIWIAGLLILLKTIGLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLADPLLRPIRRLLPAMGGIDFSPMILVL
LLYVINMGVAEVLQATGNMLLPGLWMAL
>SEQF1516_EDU87784.1 peptidase, M23B family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTVKRGDTLYRISRTTGTSVKELARLNGISPPYTIEVGQ
KLKLGGAKSSSSTRKSTAKSTTKTASVTPSSAVPKSSWPPVGQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYA
AGAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGSTDAASVRLHFQIRYRATAIDPLR
YLPPQGSKPKC
>SEQF1516_EDU87785.1 transcriptional regulator GalR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATIKDVARLAGVSVATVSRVINNSPKASEASRLAVHSAMESLSYHPNANARALAQQTTETVGLVVGDVSDPFFGAMVKA
VEQVAYHTGNFLLIGNGYHNEQKERQAIEQLIRHRCAALVVHAKMIPDADLASLLKQMPGMVLINRILPGFENRCIALDD
RYGAWLATRHLIQQGHTRIGYLCSNHSISDAEDRLQGYYDALAESGIAANDRLVTFGEPDESGGEQAMTELLGRGRNFTA
VACYNDSMAAGAMGVLNDNGIDVPGEISLIGFDDVLVSRYVRPRLTTVRYPIVTMATQAAELALALADNRPLPEITNVFS
PTLVRRHSVSTPSLEASHHATSD
>SEQF1516_EDU87786.1 hypothetical protein ECH7EC4501_1953 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNITFSHALFYQKSLIFTFFTIMLLSSIGNLHNLHVVFYILKKQIDSVRTRNDIGNINSFIRDKYLKRFPLLYSKFI
>SEQF1516_EDU87787.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFIAWYWIVLIVLVVVGYFLHLKRYCRAFRQDRDALLEARNKYLNSTREETAEKVE
>SEQF1516_EDU87788.1 small-conductance mechanosensitive channel [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLIIARMISNAVNRLMISRKIDATVADFLSALVRYGIIAF
TLIAALGRVGVQTASVIAVLGAAGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADG
KIIVIPNGKIIAGNIINFSREPVRRNEFIIGVAYDSDIDQVKQILTNIIQSEDRILKDREMTVRLNELGASSINFVVRVW
SNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVNFKRVKEDKAA
>SEQF1516_EDU87789.1 transcriptional regulator, LuxR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKIKIVVSDQQPFMIDGIIGFLGHYPDLYEVVGGYKDLKKAIAECNKSAAQIFILGEFAGGMMGAELVKWVKSHKIDAH
IITFVAKMPYIDSIKLLEAGAKGCVWKTSHPAKLNRAIDSISNGYTYFDSVHMDCEKISSRYSSDNQLTNRESEILQLIA
DGKTNKEIANFLQLSRKTVETHRLNIMKKLDVHSGIELIKTALRMGVCTI
>SEQF1516_EDU87790.1 lysophospholipid transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQFYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGR
VMMFANGLKLLGAASICFGINPFLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLAD
WHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGETRFSLVGTSLFWGAGVTLRFLLV
LWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKLVTLETVSRCMPAGILIGVVVLIFSLQHEQLPAYALLMLIGVLGG
FFVVPLNALLQERGKKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGIPVVPIGIGFGALFALAITALWIWQRRH
>SEQF1516_EDU87791.1 hypothetical protein ECH7EC4501_2042 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRICIRLSTYQKIILRQYERLRRDVEEISRKGISWLNMLV
>SEQF1516_EDU87792.1 iron ABC transporter, permease protein FitC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMRTGLVTVIFLALLLVGCVVYPGIGARFIAPQTVLQAFLHFEPQNFDHNVIVRLRLPRLAAALLTGASLGVAGALLQAV
IRNPLGEPHILGLNAGAALAVVAASALGLAFPVGRPLLASTGGALLFLLILLLSSAGRSGLTPMKVTLCGVALSAFVSSI
TAAILILDEQTLLAMRTWLAGDLAGQDWATLGTSAWFSLGGVVLAIYLAPSLNMLALGDRMAQGLGVSVLRTRTFTLLAI
ALLCGAAVSIAGPIGFVGLLVPQIVRRLVSADLRVLLPLSACVGALLLLLADIIARTLFTPHELATGVMTALVGAPVFVI
MATRMFK
>SEQF1516_EDU87793.1 glutathionylspermidine amidase/glutathionylspermidine synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVFRSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGM
AWEIFSLRFLREVVNDNILPLQAFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQ
WTRELEMVVENGCYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLENKGQFDGKWLDEKDPLQNAYVQA
NGQVINQDPYHYYTITESAEQELIKATNELHLMYLHATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFC
MDERGLKVYEYNADSASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEENYHAQFME
QALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQIREVSDREFAAVPIRTGHPQNEVRLIDVLL
RPEVLVFEPLWTVIPGNKAILPILWSLFPHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDKTSGKF
AEQKNIYQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLIVVKE
>SEQF1516_EDU87794.1 xanthine dehydrogenase, FAD-binding subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFDFASYHRAATLADAINLLADNPQAKLLAGGTDVLIQLHHHNDRYRHIVDIHNLAELRGITLAEDGSLRIGSATTFTQL
IEDSITQRHLPALCAAASSIAGPQIRNVATYGGNICNGATSADSATPTLIYDAKLEIHSPRGVRFVPINGFHTGPGKVSL
EHDEILVAFHFPPQPKEHVGSAHFKYAMRDAMDISTIGCAAHCRLDNGNFSELRLAFGVAAPTPIRCQHAEQTAQNAPLN
LQTLEAISESVLQDVAPRSSWRASKEFRLHLIQTMTKKVISEAVAAAGGKLQ
>SEQF1516_EDU87795.1 serine transporter family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAVVLFITALVAWPLTYWPHKALCQFILSSKTSAGEGITGAVTHY
YGKKIGNLITTLYFIAFFVVVLIYAVAITNSLTEQLAKHMVIDLRIRMLVSLGVVLILNLIFLMGRHATIRVMGFLVFPL
IAYFLFLSIYLVGSWQPDLLTTQVEFNQNTLHQIWISIPVMVFAFSHTPIISTFAIDRREKYGEHAMDKCKKIMKVAYLI
ICISVLFFVFSCLLSIPPSYIEAAKEEGVTILSALSMLPNAPAWLSISGIIVAVVAMSKSFLGTYFGVIEGATEVVKTTL
QQVGVKKSRAFNRALSIMLVSLITFIVCCINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPWRSIGNLITLIVGI
LCVSVMFFS
>SEQF1516_EDU87796.1 glutathione S-transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDNTYQPAKVWTWDKSAGGAFANINRPVSGPTHEKTLPVGKHPLQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLI
RIGDGDQFSSGFVEVNPNSKIPALRDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGG
FGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGNVVLGGVYDAAEFLDAGSYKHVQ
RWAKEVGERPAVKRGRIVNRTNGPLNEQLHERHDASDFETNTEDKRQG
>SEQF1516_EDU87797.1 type III secretion apparatus protein OrgA/MxiK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILLQYNLSVEHFNLNSSLIYYINNWNLLPLICLLSGCHFYRERFAERGFFYKVPDVLRDYLSAIPLEINEKARYKPGIA
NYHNIITCGFSTLLPYIRQQPLAMQQRFNLLFPDFVDHILSPLPLASTLLERITFYAKKNRDELDKISCKWCCD
>SEQF1516_EDU87798.1 hypothetical protein ECH7EC4501_2143 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSPVIYSYSVAKTWHIFCLNRKINNAIDAPFTTHLLWLSIS
>SEQF1516_EDU87799.1 anion transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPSTEWWRYLAPLAVIAIIALIPVPAGLESHTWLYFAVFTGVIVGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLA
QPGFKFTAKSLSWAVSGFSNSVIWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSA
RGAGIIYPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLLIGLMKSASHATLSWGDWFLGML
PLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETELQAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALM
LLLRIISWDDIVSNKAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLSGYSPTMVMVALIVVFYLLRYFFASATAY
TSALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYGSGYLPTADYWRLGAIFGLIFLVLLVITGLL
WMPVVLL
>SEQF1516_EDU87800.1 IS629 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTPETLRVWVRQHERDTGGGDGGLTSAERQRLKELEREN
RELRRSNDILRQASAYFAKAEFDRLWKK
>SEQF1516_EDU87801.1 alcohol dehydrogenase yqhD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKTGVLDQVLDALKGMDVLEFGGIEPNPAYETLMNAVKL
VREQKVTFLLGVGGGSVLDGTKFIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDK
QAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAEGILLTLIEDGPKALKEPENYDV
RANVMWAATQALNGLIGAGVPQDWATHMLGHELTAMHGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAERVWNITEGSDD
ERIDAAIAATRNFFEQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR
>SEQF1516_EDU87802.1 hydrolase, NUDIX family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQMSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRI
AAYDTSETPWLLEMVAGMIEEGESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLA
DENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA
>SEQF1516_EDU87803.1 lysyl-tRNA synthetase LysS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDHTSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIM
GKASFVTLQDVGGRIQLYVARDDLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
QDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGAAARPFITHHNALDLDMYLRIAP
ELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFTMMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDF
GKPFEKLTMREAIKKYRPETDMADLDNFDSAKAIVESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITEYPAEVSPL
ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAGDDEAMFYDEDYVTALEHGLPPTAGLGIGID
RMVMLFTNSHTIRDVILFPAMRPVK
>SEQF1516_EDU87804.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKWAVIISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPEIDDDTGLVSYHDQQGNAMQINRDDVSQIIER
>SEQF1516_EDU87805.1 undecaprenyl-diphosphatase BacA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTAKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPL
QHEGESKGRLTLIHILLGMIPAVVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGFLTSGDIPMFAVGFITAFVVALI
AIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
>SEQF1516_EDU87806.1 hypothetical protein ECH7EC4501_2012 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNFLMRAIFSLLLLFTLSIPVISDCVAMAIESRFKYMMLLF
>SEQF1516_EDU87807.1 type III secretion outer membrane pore, YscC/HrcC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKLRITIILISVLCIFNGLLTPGAYAAAANGYVANKENLRSFFETVSSYAGKPTIVSKLAMKKQISGNFDLTEPYALI
ERLSAQMGLIWYDDGKAIYIYDSSEMRNALINLRKVSTNEFNNFLKKSGLYNSRYEIKGDGNGTFYVSGPPVYVDLVVNA
AKLMEQNSDGIEIGRNKVGIIHLVNTFVNDRTYELRGEKIVIPGMAKVLSTLLNNNIKQSTGVNVLSEISSRQQLKNVSR
MPPFPGAEEDDDLQVEKIISTAGAPETDDIQIIAYPDTNSLLVKGTVSQVDFIEKLVATLDIPKRHIELSLWIIDIDKTD
LEQLGADWSGTIKIGSSLSASFNNSGSISTLDGTQFIATIQALAQKRRAAVVARPVVLTQENIPAIFDNNRTFYTKLVGE
RTAELDEVTYGTMISVLPRFAARNQIELLLNIEDGNEINSDKTNVDDLPQVGRTLISTIARVPQGKSLLIGGYTRDTNTY
ESRKIPILGSIPFIGKLFGYEGTNANNIVRVFLIEPREIDERMMNNANEAAVDARAITQQMAKNKEINDELLQKWIKTYL
NREVVGG
>SEQF1516_EDU87808.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDMVTLEQFRYCPTHSTHPPFCYDFHYVKPGMVAIFGDNGSGKSTLAQLMAGWYPDFLPGEITGTGTLLGTPIGHLPLNE
QSATIQLVQQSPYLQLSGCTFSVEEEVAFGPENLCLAEAEIMARIDAALTLTECQPLRHRHPATLSGGETQRVVIACAIA
MQPKLLILDEAFSRLTPQASEMLLQRLQHWAFERGSLIILFERHRTPFLNYCQQAWQLQNGALQPLC
>SEQF1516_EDU87809.1 single-stranded-DNA-specific exonuclease RecJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQQIQLRRREVDETADLPAELPPLLRRLYASRGVRSAQELERSVKGMLPWQQLSGVEKAVEILYNAFREGTRIIVVGDF
DADGATSTALSVLAMRSLGCSNIDYLVPNRFEDGYGLSPEVVDQAHARGAQLIVTVDNGISSHAGVEHARSLGIPVIVTD
HHLPGDTLPAAEAIINPNLRDCNFPSKSLAGVGVAFYLMLALRTFLRDQGWFDERGIAIPNLAELLDLVALGTVADVVPL
DANNRILTWQGMSRIRAGKCRPGIKALLEVANRDAQKLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNIGEARVLAN
ELDALNQTRKEIEQGMQIEALTLCEKLERSRDTLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAGDGTLKGSG
RSIQGLHMRDALERLDTLYPGMMLKFGGHAMAAGLSLEEDKFELFQQRFGELVTEWLDPSLLQGEVVSDGPLSPAEMTME
VAQLLRDAGPWGQMFPEPLFDGHFRLLQQRLVGERHLKVMVEPVGGGPLLDGIAFNVDTALWPDNGVREVQLAYKLDINE
FRGNRSLQIIIDNIWPI
>SEQF1516_EDU87810.1 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADAPPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHG
MEVWDKDSFGHISFDDQSMGYSHLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLSDPHLCSIVWSLSPEEAQRMQQA
SEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYARQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLH
RQGKDIGQYIYLRRYERSRKHSAALMLAGMQGFRDLFSGTNPVKKLLRDIGLKLADTLPGVKPQLIRQAMGLNDLPEWLR
>SEQF1516_EDU87811.1 5,10-methenyltetrahydrofolate synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMMTYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKR
VYLPVLHPFSAGNLLFLNYHPQSELVMNRLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQ
HYKTQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW
>SEQF1516_EDU87812.1 tRNA (guanine-N(7)-)-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPVMGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVA
MAKDRPEQDFLGIEVHSPGVGACLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVP
FAELVKSKLQLGGVFHMATDWEPYAEHMIEVMSSIDGYKNLSESNDYVPRPASRPVTKFEQRGHRLGHGVWDLMFERVK
>SEQF1516_EDU87813.1 membrane-bound lytic murein transglycosylase C [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKYLALALIAPLLISCSTTKKGGTYNEAWVKDTNGFDILMGQFAHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINF
DDGTITIETIAGTEPAAHLRRAIIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLK
NRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVVQHT
AGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAMLNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANI
INTMTPGDVYQTLTTRHPSAESRRYLYKVNTAQKSYRRR
>SEQF1516_EDU87814.1 peptidase, M48B family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIRALLVAMSVATVLTGCQNMDSNGLLSSGAEAFQAYSLSDAQVKTLSDQACQEMDSKATIAPANSEYAKRLTTIANAL
GNNINGQPVNYKVYMAKDVNAFAMANGCIRVYSGLMDMMTDNEVEAVIGHEMGHVALGHVKKGMQVALGTNAVRVAAASA
GGIVGSLSQSQLGDLGEKLVNSQFSQRQEAEADDYSYDLLRQRGISPAGLATSFEKLAKLEEGRQSSMFDDHPASAERAQ
HIRDRMSADGIK
>SEQF1516_EDU87815.1 ISSfl4 ORF2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITLPTGTRIWIIAGITDMRCGFNGLASKVQNTLKDAPFSGHIFVFRGRSGKMVKILWADRDGLCLFAKRLERGRFVWPV
TREGKVHLTPAQLSMLLEGIAWQHPKRTERPGIRI
>SEQF1516_EDU87816.1 type III secretion apparatus protein EpaP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNSISLIAILSLFTLLPFIIASGTCFIKFSIVFVIVRNALGLQQVPSNMTLNGVALLLSMFVMMPVGKEIYYNSQNENL
SFNNVASVVNFVETGMSGYKSYLIKYSEPELVSFFEKIQKVNSSEDNEEIIDDDNISIFSLLPAYALSEIKSAFIIGFYI
YLPFVVVDLVISSVLLTLGMMMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLSINP
>SEQF1516_EDU87817.1 modulator of drug activity B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYDVKAEVQNFLWADVVIWQMPGWWMGAPWTVKK
YIDDVFTEGHGTLYASDGRTRKDPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGM
EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG
>SEQF1516_EDU87818.1 glycine dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQIVPKDIQLATPPQVGAPATEYAALAELKAIASRNKR
FTSYIGMGYTAVQLPPVILRNMLENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAM
AKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDIFGVLLQQVGTTGEIHDYTALISELKSRK
IVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVPMGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQT
REQHIRREKANSNICTSQVLLANIASLYAVYHGPIGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLCVEVADKAG
VLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLDIDTLDKDVAHDSRSIQPAMLRDDEILTHPVFN
RYHSETEMMRYMHSLERKDLALNQAMIPLGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLT
GYDAVCMQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVACDKNGNIDLTDLRAKAE
QAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDGANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPG
MGPIGVKAHLAPFVPGHSVVQIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQDAF
PVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLMVEPTESESKVELDRFIDAMLAIRA
EIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHPYSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ
>SEQF1516_EDU87819.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKWKVRSALVALIVLLAGCSSNAQYNSSASGNVGTAWGGDVHSTVQGVSAERAWRDPAEMIVISYSTNVPSGYDRVYSI
RINELEYAIRDGNFNSLPITRVYDSSNNEPRYIVHARVGMNYQLYVRNYSRNTNYEIVATVDGLDVLNGKQGSLNNNGYI
VNAGDSLAIKGFRKDKHTEAAFQFANVADSYAANSAQGDVRNTGVIGFAAFELQGQAQNALPPCSGQAFPADNNGYAPPP
CRK
>SEQF1516_EDU87820.1 NleE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINPVTNTQGVSPINTKYAEHVVKNIYPEIKHDYFNESPNIYDKKYISGITRGVAELKQEEFVNEKARRFSYMKTMYSVC
PEAFEPISRNEASTPEGSWLTVISGKRPMGQFSVDSLYNPDLHALCELPDICCKIFPKENNDFLYIVVVYRNDSPLGEQR
ANRFIELYNIKRDIMQELNYELPELKAVKSEMIIAREMGEIFSYMPGEIDSYMKYINNKLSKIE
>SEQF1516_EDU87821.1 transcriptional regulator, LuxR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQVFSSDVYFTVGTNALLASQKEYYSDLVALVDLGHSFVVIDEHQHRNLKPNTEPVNILLSNNFIWINKNITLSDLTHFL
VSNLHTQNVYSTQEPLTHDEIDILRLCVSYSLKQIAIIKGIDYKTVSYHKIRALNQLNIKGTVELFIALCEWDKHYFKLQ
SCVRES
>SEQF1516_EDU87822.1 mannitol-specific cryptic phosphotransferase enzyme IIA component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLSDYFPESSISVIHSAKDWQEAIDFSMVSLLDKNYISENYIQAIKDSTINNGPYYILAPGVAMPHARPECGALKTGMS
LTLLEQGVYFPGNDEPIKLLIGLSAADADSHIGAIQALSELLCEEEILEQLLTASSEKQLADIISRG
>SEQF1516_EDU87823.1 Ent protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPIINKSASNYVEYISKNNPPYLSKKRDASINLNGKVSDCNGEIIWCRHIASYWSEFFCSNSGKIDYETFSSPQLLSKAI
VIQENKGTNNIKGDVYFVENESWGSVIYNLFLQLEKENKSHTSLEVHSPGHAMALGIKIKNDKENKFVINFYDPNQTATH
KRVFFCTNNICDIINLTAYDFLSEQCLKCYGLKEDTLSLFVDKTKSNDNNNVFIKKLPDNILQGVVINFAMGAGLREIIK
KVYNDTRFTDLTKSQMKILCESKNVNNVPGLLLALQNGHDNVIDEYGTLIKKSNLNKEELIHILSARTLDGTIPGLYQAL
QNGHAQAIKSYGNLVLDTINKNIDLEYLLSAFKYEAHSSNKYTPGLFSAFQNGHADAIKAYCGVLGNSNLKRGEIIRMLE
ARNYDGAPGLLLAYQNGDINTIQSFFDSLIMLDISKDFIEELLTAKHYDFTGLSLAISHRHDHVVKLYGKLFKKLDTSPY
KMSIILALAIDCERNNANIIIDSEYKSNKAVKEYVEILKEFNICPEKVAEYLSEFSGKHFLDVYNYYSN
>SEQF1516_EDU87824.1 protein icc [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQAVLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEG
IASFRAPCVWLPGNHDFQPAMYSALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLLATPSTCVQFKPHCSNFTLDTIA
PGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY
>SEQF1516_EDU87825.1 D-erythrose-4-phosphate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGMAHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHE
RSLQSLPWRELGVDVVLDCTGVYGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCI
IPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAGITRFFPQFNDRFEAIAVRVPTI
NVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIVDYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEW
GFANRMLDTTLAMATVAFR
>SEQF1516_EDU87826.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDDFINEVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEE
HQAIVRKWLEERNLDEVRTSELFDVWWD
>SEQF1516_EDU87827.1 xanthine/uracil permease family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDINHAGSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPALIVGAALQLSAETTAYLVSMAMIASGIGTWLQVNRYG
IVGSGLLSIQSVNFSFVTVMIALGSSMKSDGFHEELIMSSLLGVSFVGAFLVVGSSFILPYLRRVITPTVSGIVVLMIGL
SLIKVGIIDFGGGFAAKSSGTFGNYEHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGLCVGYIASLCLGMVDFSSMRNLP
LITIPHPFKYGFSFSFHQFLVVGTIYLLSVLEAVGDITATAMVSRRPIQGEEYQSRLKGGVLADGLVSVIASAVGSLPLT
TFAQNNGVIQMTGVASRYVGRTIAVMLVILGLFPMIGGFFTTIPSAVLGGAMTLMFSMIAIAGIRIIITNGLKRRETLIV
ATSLGLGLGVSYDPEIFKILPASIYVLVENPICAGGLTAILLNIILPGGYRQENVLPGITSAEEMD
>SEQF1516_EDU87828.1 site-specific recombinase, phage integrase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRILGKEKTLALVVYPEVSLSEARTKRDEARKLISEGVD
PCEQKRAKKVVPDLQLSFEHIARRWHASNKQWAQSHSDKVLKSLETHVFPFIGNRDITTLNTPDLLIPVRAAEAKQIYEI
ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALDLSRLPELLSRIGSYKGQPVTQLAVMLNLLVFIRSS
ELRYARWSEIDIDNAMWTIPAEREPLPGVKFSHRGSKMRTPHLVPLSKQVVAILAELQTWAGENGLIFTGAHDPRKPISE
NTVNKALRVMGYDTTQDVCGHGFRAMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEERRLMLQWWADFLD
ANRERFISPFEYAKINNPLKQ
>SEQF1516_EDU87829.1 TonB system transport protein ExbD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMHLNENLDDNGEMHDINVTPFIDVMLVLLIIFMVAAPLATVDVKVNLPASTSTPQPRPEKPVYLSVKADNSMFIGNDP
VTDETMITALNALTEGKKDTTIFFRADKTVDYETLMKVMDTLHQAGYLKIGLVGEETAKAK
>SEQF1516_EDU87830.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINKLLLAYLIGLVVTSTLIFIFSEEKVTYRLFAAIITGLTWPLSLIPSIISLMIRKSD
>SEQF1516_EDU87831.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMRKMLLAAALSVTAMTAHADYQCSVTPRDDVIVSPQTVQVKGENGNLVITPDGNVMYNGKQYSLNAAQREQAKDYQAEL
RSTLPWIDEGAKSRVEKARIALDKIIVQEMGESSKMRSRLTKLDAQLKEQMNRIIETRSDGLTFHYKAIDQVRAEGQQLV
NQAMGGILQDSINEMGAKAVLKSGGNPLQNVLGSLGGLQSSIQTEWKKQEKDFQQFGKDVCSRVVTLEDSRKALVGNLK
>SEQF1516_EDU87832.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKREEICRLLADKVNKLKNKENSLSELLPDVRLLYGETPFARTPVMYEPGIIILFSGHKIGYINERVFRYDANEYLLLTV
PLPFECETYATSEVPLAGLRLNVDILQLQELLMDIGEDEHFQPSMAASGINSATLSEEILCAAERLLDVMARPLDARILG
KQIIREILYYVLTGPCGGALLALVSRQTHFSLISRVLKRIENKYTENLSVEQLAAEANMSVSAFHHNFKSVTSTSPLQYL
KNYRLHKARMMIIHDGMKASAAAMRVGYESASQFSREFKRYFGVTPGEDAARMRAMQGN
>SEQF1516_EDU87833.1 2-deoxy-D-gluconate 3-dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVEPTETIKQVTALGRRFLSLTADLRKIDGIPGLLDRAV
AEFGHIDILVNNAGLIRREDALEFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTA
SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRWGLPSDLMGPVVFLASSASDYVN
GYTIAVDGGWLAR
>SEQF1516_EDU87834.1 L(+)-tartrate dehydratase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKILTTPIKAEDLQDIHVGDVIYLTGTLVTCRDVCHRRLIELKRPLPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTS
MRMESFEREFIEQTGVKLVVGKGGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEF
GPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK
>SEQF1516_EDU87835.1 protein SufI [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRRGQPLFMTVQRAHWSFTPGTRASVWGINGRYLGPTIR
VWKGDDVKLIYSNRLTENVSMTVAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGM
WLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQSPYVEVSRGWVRLRLLNASNSR
RYQLQMSDGRPLHVISGDQGFLPAPVSVKQLSLAPGERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLV
LTLRPTGLLPLVTDSLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADEPQAFHIEG
VMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNSQTLEMADRGSIGQLLVNPVP
>SEQF1516_EDU87836.1 channel protein, hemolysin III family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDLNASATAITSYSLYGGSMILLFLASTLYHAIPHQRAK
MWLKKFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
VKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQA
>SEQF1516_EDU87837.1 iron transport system regulatory protein FitR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIQKDKTRVDIYGERFRTRASQLTPGLRAVASYINEHREVVLDQTAMEIAATLNTSDATVIRAIQALGFAGLRDLKRTLE
QWLGPALSSSEKMSTTVSNLTSDVNTAIDFVLEGHLYTCNVLSEPENRHALAQAVALLVQARQVAIFGIGASGILADYTA
RLFNRIGLPATALNRTGIGLAEQLIALQRGDVLIMMAQKSAHREGLTTLREARRLGIPVILLTNALDSRFSKDASIVIHV
PRGDEKGKTPLHGTVLLCLEMIVWSVASAVPQRAVKTIKRINDFHRGLKTGRKNG
>SEQF1516_EDU87838.1 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKVVLATGNAGKVRELASLLSDFGLDIVAQTELGVDSAEETGLTFIENAILKARHAAKVTGLPAIADDSGLAVDVLGGA
PGIYSARYSGEDATDQKNLQKLLETLKDVPDDQRQARFHCVLVYLRHAEDPTPLVCHGSWPGVITREPAGTGGFGYDPIF
FVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG
>SEQF1516_EDU87839.1 IS66 family element, orf2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPS
ARDGKVFLTQAQLAMLLEGIDWRQPKRLLTSLTML
>SEQF1516_EDU87840.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLENLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAE
DRGFILHTPPSNFASSIRISDNTVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKT
PIADRWREAAKLIGVDILTMPGVAGHA
>SEQF1516_EDU87841.1 hypothetical protein ECH7EC4501_1955 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNISIVSVSIIFLCDVSRDAKLLLIDSLIFLYLSFLNYEF
>SEQF1516_EDU87842.1 hypothetical protein ECH7EC4501_2078 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDRRSRRIRQKNRLHNNIILPDHVSPQIIITTETDYTNHNRQRFVIFPYYYSVFTVVTFLFSKVLIADNSV
>SEQF1516_EDU87843.1 hypothetical protein ECH7EC4501_1977 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILSPTLKLICQFIFAHIGIISRIIYIILIERINIPLLFDMLSKHGSVISKPSFVSNV
>SEQF1516_EDU87844.1 type III secretion apparatus lipoprotein EprK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKYISLLLFILLLCGCKQQELLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIYVEPTDFASAVDWLKIYNLPGKPD
IQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDGIVSSRVHVSYDVDTGDSGKTALPIHISVLAVYEKDINPEI
KINDIKRFIVNSFASVQYENISVVLSKRRDIIEQAPTYEISEPVFAYDKAMPVSILLALISVATCWLLWKYRAILTNLVR
LKIK
>SEQF1516_EDU87845.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFFDIFSALNIALFKLTFSSHHLYIETCVFFGFLFCCDFGVF
>SEQF1516_EDU87846.1 hypothetical protein ECH7EC4501_1952 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLIHDILHCKEMSKMKDVDQNFDALDCHILREYLILLFYD
>SEQF1516_EDU87847.1 hydrogenase assembly chaperone HybG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADLLGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDIT
SA
>SEQF1516_EDU87848.1 putative Holliday junction resolvase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNLIERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFA
NRIHGRFGVEVKLHDERLSTVEARSGLFEQGGYRALNKGKIDSASAVIILESYFEQGY
>SEQF1516_EDU87849.1 xanthine dehydrogenase, iron-sulfur binding subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNHSETITIECTINGMPFQLHAVPGTPLSELLREQGLLSVKQGCCVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLE
GEAKGGKLSHVQQAYAKSGAVQCGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK
>SEQF1516_EDU87850.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQQPVRLRVSGGIPQVIKCRTVTEVNGGGIFQREEQRMCLTCPCSGSKSGFGNGLRGHRRVTYQAVRTFNLSSEVG
>SEQF1516_EDU87851.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHPFTSLTLWALAACTTLILPAQTILPIYSAATFFCLIALKATRRRAKYVVWLMFSLGAGLWLVHGGWLTEWLSGTPRSP
ERWTHAITLWLRILAIVSTSQLWMQYVPVQCFIRALFASRLPPGVAYLFAGPLLVVEQLKRQLAIIHEAQRARGVPLDEG
WYQRLRAMPALTIPLTHNALNDLAVRGAALDMRAFRIHNRRTTLWAPADSTLQRVARYTMILLMLTEFGAWIWLR
>SEQF1516_EDU87852.1 adenylate cyclase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETPDNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQ
RPEYNVALSEPTLDLAQLPTEVWPNGELPADLASRVQPLFSTDFYREKWLVAVDGSRIEIALDQGEVKAGEFAEPICELE
LELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAKADVEQGLEAALELALAQWQYHE
ELWVRGNDAAKEQVLAAISLVRHTLMLFGGIVPRKASTHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSK
AWQPFLDAKAQGKISDSFKRFADIHLSRHAAELKSVFCQPLGDRYRDQLPRLTRDIDSILLLAGYYDPVVAQAWLENWQG
LHHAIATGQRIEIEHFRNEANNQEPFWLHSGKR
>SEQF1516_EDU87853.1 hypothetical protein ECH7EC4501_1969 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQQIEVLGLKFAVKEKMKFGSIHCQALLKIALFLQNNISLAVNC
>SEQF1516_EDU87854.1 arginine exporter protein ArgO [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCAISDLVLICAGIFGGSALLMQSPWLLALVTWGGVVFL
LWYGFGAFKTAMSSNIELASAEVLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
FGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS
>SEQF1516_EDU87855.1 xanthine dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEAREATATGESCMRVDAIAKVTGRARYTDDYVMAGMCYAKYVRSPIAHGYAVSINDEQARSLPGVLAIFTWEDVPDIPF
ATAGHAWTLDENKRDTADRALLTRHVRHHGDAVAIVVARDELTAEKAAQLVSIEWEELPVITTPEAALAEDAAPIHNGGN
LLKQSTMSTGNVQQTIDAADYQVQGHYQTPVIQHCHMESVTSLAWMEDDSRITIVSSTQIPHIVRRVVGQALDIPWSCVR
VIKTFVGGGFGNKQDVLEEPMAAFLTSKLGGIPVKVSLSREECFLATRTRHAFTIDGQMGVNRDGTLKGYSLDVLSNTGA
YVSHGHSIASAGGNKVAYLYPRCAYAYSSKTCYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEIRLRNASRE
GDANPLTGKRIYSAGLPECLEKGRKIFEWEKRRAECQNQQGNLRRGVGVACFSYTSNTWPVGVEIAGARLLMNQDGTINV
QSGATEIGQGADTVFSQMVAETVGVPVSDVRVISTQDTDVTPFDPGAFASRQSYVAAPALRSAALLLKEKIIAHAAVMLH
QSAMNLTLIKGHIVLVERPEEPLMSLKDLAMDAFYHPERGGQLSAESSIKTTTNPPAFGCTFVDLTVDIALCKVTINRIL
NVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDAKSGVVRNPNLLDYKMPTMPDLPQLESAFVEINEPQSAYGHKS
LGEPPIIPVAAAIRNAVKMATGVAINTLPLTPKRLYEEFHLAGLI
>SEQF1516_EDU87856.1 tyrosine recombinase XerD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQDLARIEQFLDALWLEKNLAENTLNAYRRDLSMMVEWLHHRGLTLATAQSDDLQALLAERLEGGYKATSSARLLSAVR
RLFQYLYREKFREDDPSAHLASPKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDI
SLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQMTRQTLWHRIKHYAVLAGIDSEK
LSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLRQLHQQHHPRA
>SEQF1516_EDU87857.1 putative selenium-dependent hydroxylase accessory protein YqeC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSIVDPSALFIDLGAQKRPTVISVVGAGGKTSLLFWLAELLQASGRRVLITTTTHMFMPTSHWPVVFCRDPAMLPHASL
TSPISFCFHSWKANLGKVQGFTPEAIDALVQRPECDVILIEADGSCAMPLKAPDEHEPCIPKSSCCVIAVMGGHILGAKV
STENVHRWSQFADITGLTPDATLQLSDLVALVRHPQGAFKNVPQGCRRVWFINRFSQCENAIAQSELLQPLQQHDVEAIW
LGDIQEHPAIARRFVN
>SEQF1516_EDU87858.1 hypothetical protein ECH7EC4501_2154 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFFIVIASALALNAHFCQCLAYFSRVLEKCYKIAHNQIAALFLRNYAI
>SEQF1516_EDU87859.1 LAO/AO transport system ATPase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINEATLAESIRRLRQGEHATLAQAMTLVESRHPRHQALSTQLLDAIMPYCGNTLRLGVTGTPGAGKSTFLEAFGMLLIR
EGLKVAVIAVDPSSPVTGGSILGDKTRMNDLARAEAAFIRPVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQS
ETEVARMVDCFISLQIAGGGDDLQGIKKGLMEVADLIVINKDDGDNHTNVAIARHMYESALHILRRKYDEWQPRVLTCSA
LEKRGIDEIWHAIIDFKTALTASGRLQQVRQQQSVEWLRKQTEEEVLNHLFANEDFDRYYRQTLLAVKNNTLSPRTGLRQ
LSEFIQTQYFD
>SEQF1516_EDU87860.1 arabinose-proton symporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVTINTESALTPRSLRDTRRMNMFVSVAAAVAGLLFGLDIGVIAGALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNG
WLSFRLGRKYSLMAGAILFVLGSIGSAFATSVEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLG
IVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAEKGRHIEAEEVLRMLRDTSEKAREELNEIRESLK
LKQGGWALFKINRNVRRAVFLGMLLQAMQQFTGMNIIMYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDK
AGRKPALKIGFSVMALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKCRDFGITCS
TTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTALNIAFVGITFWLIPETKNVTLEHIERKLMAGEKLRNIGV
>SEQF1516_EDU87861.1 S-adenosylmethionine synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACETYVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVH
SDMGFDANSCAVLSAIGKQSPDINQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPW
LRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLTSATKFFINPTGRFVIGGPMGDC
GLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAAYAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEK
VPSEQLTLLVREFFDLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK
>SEQF1516_EDU87862.1 3,4-dihydroxy-2-butanone 4-phosphate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMIFPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDL
PMMVENNTSAYGTGFTVTIEAAEGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDL
MTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS
>SEQF1516_EDU87863.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQHKQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEV
HIEGYTPEDKK
>SEQF1516_EDU87864.1 Ni/Fe-hydrogenase 2 b-type cytochrome subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHDPQPLGGKIISKPVMIFGPLIVICMLLIVKRLVFGLGSVSDLNGGFPWGVWIAFDLLIGTGFACGGWALAWAVYVFN
RGQYHPLVRPALLASLFGYSLGGLSITIDVGRYWNLPYFYIPGHFNVNSVLFETAVCMTIYIGVMALEFAPALFERLGWK
VSLQHLNKVMFFIIALGALLPTMHQSSMGSLMISAGYKVHPLWQSYEMLPLFSLLTAFIMGFSIVIFEGSLVQAGLRGNG
PDEKSLFVKLTNTISVLLAIFIVLRFGELIYRDKLSLAFAGDFYSVMFWIEVLLMLFPLVVLRVAKLRNDSRMLFLSALS
ALLGCATWRLTYSLVAFNPGGGYAYFPTWEELLISIGFVAIEICAYIVLIRLLPILPPLKQNDHNRHEASKA
>SEQF1516_EDU87865.1 diaminopropionate ammonia-lyase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVFSLKIDIADNKFFNGETSPLFSQSQAKLARQFHQKIAGYRPTPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLG
GAYAIAQLLCEKYHLDIETLSFEHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAE
CIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMREMGVTPTHVLLQAGVGAMAGGV
LGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIVNVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALG
MRVLGNPYGNDPRIISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVWEGKHAVAP
>SEQF1516_EDU87866.1 hypothetical protein ECH7EC4501_1961 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLFSRKNFIFNYISLLFHQCILWILLIIIMKGMIINECVKAFTLRMNIWEKLKL
>SEQF1516_EDU87867.1 putative oxygen-independent coproporphyrinogen III oxidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLLNDLDNDVAYAQGREVKTIFIGGGTPSLLSGSAMQTL
LDGVRARLPLAADAEITMEANPGTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSF
NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALWDIFEQGHQLLTAAGYQQYETSA
YAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDGRILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLE
PAPRVEFSAYTGLCEDVIRPQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE
>SEQF1516_EDU87868.1 hypothetical protein ECH7EC4501_0903 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINILKKSPIERLCASVSITPHEMALALAGLNPSMRIGDVPQDKFEQVESARTMIARAIWLHSGKKAGKDEPYRAGDIFL
ASFPFIEAGTPEAIITAVTDAIDDLRGTKNWEEKALNLGGRRLVSHIKETSRSGRGQYRKLDEEQGNMKMMGLLVLLLVK
KSGTTAYIQDGEPNRSAIYRDVEALMKEKGISPKGIAKSTFMQKISAALLAVSQAD
>SEQF1516_EDU87869.1 DNA gyrase subunit B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGIRSLPMIKLLTGLLLLAWPFVIWFGLAHNGLHWLLPLMALLLLLRLRQTRRQAGPLQAVTQLVAVVGIALCVASFML
KTHQLLLFYPVVVNAVMLAVFGGSLWSAMPIVERLARLQEPDLPEKGVRYTRHVTQIWCGFFIINGGIALFTALYADMSL
WTAWNGMIAYLLMGTLMAGEWLLRRQVMKRDRA
>SEQF1516_EDU87870.1 lipopolysaccharide 1,2-glucosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFKHLTQFKDIIELDKRPVKLDERETFNVSWGIDENYQVGAAISIASILENNKQNKFTFHIIADYLDKEYIELLSQLAT
KYQTVIKLYHIDSEPLKALPQSNIWPVSIYYRLLSFDYFSARLDSLLYLDADIVCKGSLNELIALEFKDEYGAVVIDVDA
MQSKSAERLCNEDFNGSYFNSGVMYINLREWLKQRLTEKFFDLLSDESIIKKLKYPDQDILNLMFLHHAKILPRKYNCIY
TIKSEFEEKNSEYYTRFINDDTVFIHYTGITKPWHDWANYASADYFRNIYNISPWRNIPYKKAVKKHEYKEKYKHLLYQK
KFLDGVFTAIKYNVMKG
>SEQF1516_EDU87871.1 AMP-dependent synthetase and ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQTLPLARWLTAPRPDDTPIAWLNESTWTLGDLRHDVAQLICRLQQQPGERWALCFENSYLFIVALLATLHAGKTPVLP
GHNRVIQLNEQRELFDGVLSDSELNWQGSLLLVASSPQIATQSFTFAAIAPEAFIELFTSGSTGQPKRAIKPVHLLDREA
ELLAERLGARLAGCRVVGSVLPQHLYGLTFRVFLPMALGLPLHAAMLWYVEQFAALSHQHRYIFISSPAFLKRLDTQLSP
PPVQVLLSAGGELPWQDVQHTASWLRVWPDEIYGSTETGVIAWRYREQEQRRWLPLPGMQFQAEGDAFRLFSPLIAEDNG
MLLDDILQFSEDGQFHLMGRRGRIVKIEEKRISLQEVEQRLLALDGIREAAAVPVTRGGRQSIGVLLVLDDEAHLQWQNG
GGHSQEMTWRRLLRPTLEPVAIPRYWRVIDEMPVNSMNKRVYAQLQELFHEAP
>SEQF1516_EDU87872.1 bacteriophage P4 DNA primase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSAPNLKKQPRGKKHADTEVIIFAGSDAWAHAKQWLEQDGKLAGDNIPPVVLADEQLKDIGNLQIVPDGRKSARIYKAG
HLDQVMVKGIGQKLAAAGVQDADYYPEGMHHNERQNWRNYLETERKNISDGLVIELPVKKKERGKGDDATSLALNQMGAS
QRGEVLLAHYGGELAINADSDTVHYYNSVVWVPVQDKELQRTMAQIFIDEDICYSQNAIKSAVDTMKLSLPVMGNTARNL
IGFSNGVFDTRTGDFREHDKNDWLLIASELPFTPPAEGETLATHAPNFWKWLRRSVAENDRKADRVLAALFMVLANRYDW
QLFIEVTGPGGSGKSVMAEICTMLAGKANTVSASMKALEDARERALVVGFSLIILPDMTRYAGDGAGIKAITGGDKVAID
PKHKAPYSTRIPAVVLAVNNSAMSFSDRSGGISRRRVIFNFSEVVPENERDPMLPEKIEGELAVVIRHLLTRFADQDEAR
RLLYEQQKSEEALAIKREGDSLVDFCGYLMSSVMCDGLLVGNAEIIPFSPRRYLYHAYLSYMRAHGFSKPVTLTRFGADM
PGAMAEYGREYMKKRTKEGVRSNVILTDESEDWLPSCAPVKNEGDKN
>SEQF1516_EDU87873.1 glycerophosphoryl diester phosphodiesterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVD
AGSWYGKAFKGEPLPLLSQVAERCREHGMMANIEIKPTTGTGPLTGKMVALAARELWAGMTPPLLSSFEIDALEAAQQAV
PELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLDKARVMQLKDAGLRILVYTVNKPQRAAELLRWGVDCICTDAIDVI
GPNFTAQ
>SEQF1516_EDU87874.1 gamma-glutamyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKPTFLRRVAIAALFTGSCFSTVAAPPAPSPVSYGVEEDVFHPVRAKQGMVASVDATATQVGVDILKEGGNAVDAAVAV
GYALAVTHPQAGNLGGGGFMLIRSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALD
KYGTMPLNKVVQPAFKLARDGFIVNDELADDLKTYGSEVLPNHENSKAIFWKEGEPLKKGDKLVQANLAKSLEMIAENGP
DEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGS
ADAMQIMAEAEKYAYADRSEYLGDPDFVKVPWQALTNKAYAKSIAEQIDINKAKPSSEIRPGKLAPYESNQTTHYSVVDK
DGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGDANAVGPNKRPLSSMSPTIVVKDGKTWLVT
GSPGGSLIITTVLQMVVNSIDYGMNVAEATNAPRFHHQWLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVG
PDGELYGASDPRSVDDLTAGY
>SEQF1516_EDU87875.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNISEVDLHKLTVSDPFLGQYQQLVRDVVIPYQWDALNDRIPEAEPSHAIENFRIAAGLQEGEFYGMVFQDSDVAKWLEA
VAWSLCQKPDAELEKTADEVIELIASAQCEDGYLNTYFTVKAPEERWSNLAECHELYCAGHLIEAGVAFFQATGKRRLLG
VVCRLADHIDSVFGPDESKLHGYPGHPEIELALMRLYEVTEEPRYLALTNYFVEQRGAQPHYYDQEYEKRGQTSHWHTYG
PAWMVKDKAYSQAHLPLAQQQTAIGHAVRFVYLMTGVAHLARLSHDDSKRQDCLRLWNNMAQRQLYITGGIGSQSSGEAF
SSDYDLPNDTVYAESCASIGLMMFARRMLEMEGDSQYADVMERALYNTVLGGMALDGKHFFYVNPLEVHPKSLKFNHIYD
HVKPIRQRWFGCACCPPNIARVLTSIGHYLYTPREDALYINIYAGNSMEVPVENGTLRLRVSGNYPWQEQVTIAVESPQP
VRHTLALRLPDWCTQPQIILNGEEVEQDIRKGYLHITREWQEGDTLNLTLPMPVRRVYGNPLVRHVAGKVAIQRGPLVYC
LEKADNGESLHNLWLPTDAPFTTFEGKGLFSHKILIQAPGYRYEQSNPEQQPLWHYDSAPAKRQTQTLTFIPWFSWANRG
EGEMRIWVNEEKHCHP
>SEQF1516_EDU87876.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSQEKWTMSDIALTVSILALVAVVGLFIGNVKFRGIGLGIGGVLFGGIIVGHFVSQAGMTLSSDMLHVIQEFGLILFVY
TIGIQVGPGFFASLRVSGLRLNLFAVLIVIIGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMEM
VDQMGMSYAMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESSRTNGGALIKTINIRVENPNLHDLAIKDVPILNGDKI
ICSRLKREETLKVPSPDTIIQLGDLLHLVGQPADLHNAQLVIGQEVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFK
ERYDVVISRLNRAGVELVASGDISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVP
GFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKSGGDFVNTLVNGEGLSWIGYGAL
ITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPPALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSI
G
>SEQF1516_EDU87877.1 nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKVRLAIIGNGMVGHRFIEDLLDKSDAANFDITVFCEEPRIAYDRVHLSSYFSHHTAEELSLVREGFYEKHGIKVLVGE
RAITINRQEKVIHSSAGRTVFYDKLIMATGSYPWIPPIKGSDTQDCFVYRTIEDLNAIESCARRSKRGAVVGGGLLGLEA
AGALKNLGIETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQEGVEARKTMRFADGSELEVDFIVFS
TGIRPRDKLATQCGLDVAPRGGIVINDSCQTSDPDIYAIGECASWNNRVFGLVAPGYKMAQVAVDHILGSENAFEGADLS
AKLKLLGVDVGGIGDAHGRTPGARSYVYLDESKEIYKRLIVSEDNKTLLGAVLVGDTSDYGNLLQLVLNAIELPENPDSL
ILPAHSGSGKPSIGVDKLPDSAQICSCFDVTKGDLIAAINKGCHTVAALKAETKAGTGCGGCIPLVTQVLNAELAKQGIE
VNNNLCEHFAYSRQELFHLIRVEGIKTFEELLAKHGKGYGCEVCKPTVGSLLASCWNEYILKPEHTPLQDSNDNFLANIQ
KDGTYSVIPRSPGGEITPEGLMAVGRIAREFNLYTKITGSQRLAMFGAQKDDLPEIWRQLIEAGFETGHAYAKALRMAKT
CVGSTWCRYGVGDSVGLGVELENRYKGIRTPHKMKFGVSGCTRECSEAQGKDVGIIATEKGWNLYVCGNGGMKPRHADLL
AADIDRETLIKYLDRFMMFYIRTADKLTRTAPWLENLEGGIDYLKAVIIDDKLGLNAHLEEEMARLREAVVCEWTETVNT
PSAQTRFKHFINSDKRDPNVQMVPEREQHRPATPYERIPVTLVEDNA
>SEQF1516_EDU87878.1 nickel ABC transporter, permease protein NikB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLRYVLRRFLLLIPMVLAASVIIFLMLRLGTGDPALDYLRLSNLPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDF
GISFATQRPVLDDMLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV
YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLDVAGQRHVTWARLRGLNDKQTERRHILRNASLPMITAVGM
HIGELIGGTMIIENIFTWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAHA
>SEQF1516_EDU87879.1 acetolactate synthase, large subunit, isozyme I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASSGTSSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYDALSQSTQIRHILARHEQGAGFIAQGMARTDGKPAVC
MACSGPGATNLVTAIADARLDSIPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQVMSDAFRIAQS
GRPGPVWIDIPKDVQTAVFEIEAQPAVAEKAVAPAFSEESIRDAAAMINAAKRPVLYLGGGVINAPARVRELAEKAQLPT
TMTLMALGMLPKAHPLSLGMLGMHGVRSTNYILQEADLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPH
VAIQADVDDVLAQLIPQVEAQPRAEWHQLVADLQREFPCPIPKACDPLSHYGLINAVAACVDDNAIITTDVGQHQMWTAQ
AYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPDRKVLCFSGDGSLMMNIQEMATASENQLDVKIILMNNEALGLVHQQ
QSLFYKQGVFAATYPGKINFMQIAAGFGLETCDLNNEADPQAALQEIINRPGPALIHVRIDAEEKVYPMVPPGAANTEMV
GE
>SEQF1516_EDU87880.1 putative pimeloyl-BioC--CoA transferase BioH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHLVDLPGFGRSRGFGALSLAEMAEAVLRQAPDKAIWLG
WSLGGLVASQIALTHPERVQALVTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARA
LKKTVLALPMPEVDVLNGGLEILKTVDLRLPLQNVPMPFLRLYGYLDGLVPRKVVPMLDKLWPHSESYIFAKAAHAPFIS
HPVEFRHVLVALKQRV
>SEQF1516_EDU87881.1 sulfatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRPNFLFIMTDTQAPNMVGCYSGKPLNTQNIDSLAAEGIRFNSAYTCSPVCTPARAGLFTGIYANQSGPWTNNVAPGKN
ISTMGRYFKDAGYHTCYIGKWHLDGHDYFGTGECPPEWDADYWFDGANYLSELTEKEISLWRNGLNSVEDLQANHIDETF
TWAHRISNRAVDFLQQPARAEEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYELGEKAQDDLANKPEHHRLWAQAMPSPV
GDDGLYHHPLYFACNDFVDDQIGRVINALKPEQRENTWVIYTSDHGEMMGAHKLISKGAAMYDDITRIPLIIRSPQGERR
QVDTPVSHIDLLPTMMALADIEKPEILPGENILAVKEPRGVMVEFNRYEIEHDSFGGFIPVRCWVTDDFKLVLNLFTSDE
LYDRRNDPNEMHNLIDDAHFADVRSKMHDALLDYMDKIRDPFRSYQWSLRPWRKDAQPRWMGAFRPRPQDGYSPVVRDYD
TGLPTQGVKVEEKKQKF
>SEQF1516_EDU87882.1 cyclic diguanylate phosphodiesterase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAVELLTAVTHPLNPSQRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFIEHGLLASVNIDGPTLIALRQQPKILRQI
ERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDFGTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHL
MNRYCRGVIVEGVETPEEWRDVQNSPAFAAQGWFLSRPAPIETLNTAVLAL
>SEQF1516_EDU87883.1 EscV protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKLLNIFKKAESYHDLILALFFFMAVMMMIIPLPTVVVDIIIAINISTALLLLMLSIYIKNPLELTSFPTILLITTLMR
LSLSVSTTRLILLHHDAGDIIYSFGNFVVGGNIVVGLVIFTIITIVQFMVITKGAERVAEVSARFSLDGMPGKQMSIDGD
MRAGVIDPLEAKVLRSRVQKESQFYGSMDGAMKFVKGDAIAGIIIVLVNLFGGVLIGMWQFDMPFSAALSLFSVLSVGDA
LVAQIPALIISVTAGVVVTRVPGESEKEENLAGDIVQQVSVNSRPFLISAALMLVMAIIPGFPALVFLFLAVCLLGIAWK
LQKKRTFGTGNNKDAMGADLSNSQNISPGAEPLILNLSSNIYSSDITQQIEVMRWNFFEESGIPLPKIIVNPVKNNDSAI
EFLLYQESIYKDTLIDDTVYFEAGHAEISFEFVQEKLSTNSIVYKTNKTNQQLAHLTGMDVYATTNDKITFLLKKLVLSN
AKEFIGVQETRYLMDIMERKYNELVKELQRQLGLSKIVDILQRLVEENVSIRDLRTIFETLIFWSTKEKDVVILCEYVRI
ALRRHILGRYSVSGTLLNVWLIGSDIENELRESIRQTSSGSYLNISPERTEQIIGFLKNIMNPTGNGVILTALDIRRYVK
KMIEGSFPSVPVLSFQEVGNNIELKVLGTVNDFRA
>SEQF1516_EDU87884.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIGDDETNWGTKSLAILDMPFTAVMDTLLLPWDVFRKDSSVRSRVEKSEANAQATNAVIPPARMPDN
>SEQF1516_EDU87885.1 peptidyl-prolyl cis-trans isomerase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKSTLAAMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELELDKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQ
GGGFTEQMQQKKPNPPIKNEADNGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVAD
KISQVPTHDVGPYQNVPSKPVVILSAKVLP
>SEQF1516_EDU87886.1 Tir chaperone [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSRSELLLEKFAEKIGIGSISFNENRLCSFAIDEIYYISLSDANDEYMMIYGVCGKFPTDNSNFALEILNANLWFAENG
GPYLCYEAGAQSLLLALRFPLDDATPEKLENEIEVVVKSMENLYLVLHNQGITLENEHMKIEEISSSDNKHYYAGR
>SEQF1516_EDU87887.1 glutamine-fructose-6-phosphate transaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMTRLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGE
PSEVNAHPHVSEHIVVVHNGIIENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTV
IMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRRSVNIFDKTGAEVKRQDIESNLQ
YDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQVDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAG
IPCDVEIASEFRYRKSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMTNAGTEIGV
ASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLSQDKRIEALAEDFSDKHHALFLGRGDQYPIA
LEGALKLKEISYIHAEAYAAGELKHGPLALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFAEQDAGFVSSDNM
HIIEMPHVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE
>SEQF1516_EDU87888.1 ShET2 enterotoxin, N- region family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDNVTVSRVCIQSPSFVPDLDGEKNKSQLFVDDIVAYLKSPSVYSLEKEGPLNHFVNHCSEVELGFYSDGAYSILVSRS
KQQPEGMILTVSDADAINIVHISVSPVLIKFLDDIFTCLHTYPDDESFTKEQIKANSKYDIVDYNCLLHFTGKPKSLIEC
RHFALQYCIDSMNEHTGKVPLKAYYSSPEDIQKHIPFELEQQFNNLQKNPPPGTCVVASDKFGEALSVFFHRMEKEKLTH
MTAIVQSQTHAMAVRLRIKKTPAGETEYVVSFYDPNATNTAVRYKANNCDSFGSLQSFINIQQAKQKWVITDICSECVGI
TPYLPREQAHLLSGIENELQPPLSPPALFLLMRMGIYKNIVLFFDKLKNSQEMTASKALDILAAKSPEGIYGLCVLLYHN
TIDKFNDYITNLKELTRKYNFSQEDLETLLLAKDNLGVSWIPRALKNNQNKIVKAWLLAIDDFEKEFGVNKNEILLRIGK
EIDSIDDLNSAIRTNDYNVVNILLANIKAKMFKNELNKEDILKLMAAREKVAGASDKWTKASGLYSAIVKGHTKIVAAWM
ETAEVIASHYENDKDVVRELLSLSRNNAVCSLYVASYKTMSKQVIDVYLNAAIRLALQHGFTFDEILEQFTRDFDGKSFS
LAVEKADDIYGSLAENIQNCGW
>SEQF1516_EDU87889.1 dUTP diphosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGI
VLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
>SEQF1516_EDU87890.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIFNKIDYNYYKLINYPIMMVHDEWLGDLTGVNQVSFRRLRETSSTRNQLNKILRQEIHDKISGVELSDINKEGFLYQS
IGKIRLLALSSALFDIQCPDYIFSRLYRETLIREIGYQNVKQLSFYWQGGQCKPEYGEERFCAELIKYGAGNLEWLFADN
PLWTIVKYLLPKSGEIKPTHINDLFLNRLNKILLPYETL
>SEQF1516_EDU87891.1 alpha-xylosidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKISDGNWLIQPGLNLIHPLQVFEVEQQGNEMVVYAAPRDVRERTWQLDTPLFTLRFFSPQEGIVGVRIEHFQGALNNGP
HYPLNILQDVKVTIENTERYAEFKSGNLSARVSKGEFWSLDFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGE
TVYGLGERFTALVRNGQTVETWNRDGGTSTEQAYKNIPFYMTNRGYGVLVNHPQCVSFEVGSEKVSKVQFSVESEYLEYF
VIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTSFTTNYDEATVNSFIDGMAGRNLPLHVFHFDCFWMKAFQWCDFEW
DPLTFPDPEGMIRRLKAKGLKICVWINPYIGQKSPVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNPDACKWYAD
KLKGLVAMGVDCFKTDFGERIPIDVQWFDGSDPQKMHNHYAYIYNELVWNVLKDTVGEEEAVLFARSASVGAQKFPVHWG
GDCYANYESMAESLRGGLSIGLSGFGFWSHDIGGFENTALAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVR
FFTQLKCRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFSEAGDVQFYLPEGRWTHLWH
NDELDGSRWHKQQHSFLSLPVYVRDNTLLALGNNEQRPDYAWHEGTAFQLFNLQDGHEAICEVPAADGSVLFTLKAARTG
NTITVTGAGEAKNWTLCLRNIVKVNGLQGGSQAESEQGLVVTPQGNALTITL
>SEQF1516_EDU87892.1 ferrous iron transport protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQYTPDTAWKITGFSREISPAYRQKLLSLGMLPGSSFNVVRVAPLGDPIHIETRRVSLVLRKKDLALLEVEAVSC
>SEQF1516_EDU87893.1 4Fe-4S binding domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRFIIADATKCIGCRTCEVACAVSHQENQDCAALSPDEFISRIRVIKDHSWTTAVACHQCEDAPCANVCPVDAISREHG
HIFVEQTRCIGCKSCMLACPFGAMEVVSSRKKARAIKCDLCWHRETGPACVEACPTKALQCMDVEKVQRHRLRQQPV
>SEQF1516_EDU87894.1 DNA polymerase III, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSLTGTDLEMEMVARVALVQPHEPGATTVPARKFFDICR
GLPEGAEIAVQLEGERMLVRSGRSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF
ETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQIGSNNIRAHVGDFIFTSKLVDGR
FPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNEKFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFN
VSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL
>SEQF1516_EDU87895.1 HAD hydrolase, IA family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHINIAWQDVDTVLLDMDGTLLDLAFDNYFWQKLVPETWGAKNGVTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLD
ICAMTTEMGPRAVLREDTIPFLEALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAE
ATGLKAERTLFIDDSEAILDAAAQFGIRYCLGVTNPDSGIAEKQYQRHPSLNDYRRLIPSLM
>SEQF1516_EDU87896.1 small heat shock protein IbpB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNHYRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEE
KKWLHQGLMNQPFSLSFTLAENMEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS
>SEQF1516_EDU87897.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIRKRFIAGAKCPACQAQDSMAMWRENNIDIVECVKCGHQMREADKEARDHVRKDEQVIGIFHPD
>SEQF1516_EDU87898.1 DNA adenine methylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLNTDFSRYILADINSDLISLYNIVKMRTDEYVQAAREL
FVPETNCAEVYYQFREEFNKSQDPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFAEKAQNAFF
YCESYADSMARADDASVVYCDPPYAPLSATANFTAYHTNSFTLEQQAHLAEIAEGLVERHIPVLISNHDTMLTREWYQRA
KLHVVKVRRSISSNGGTRKKVDELLALYKPGVVSPAKK
>SEQF1516_EDU87899.1 L-lactate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSEVALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGL
CGMYARRGEVQAAKAADAHGIPFTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPT
PGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLEDYIGWLGNNFDPSISWKDLEWI
RDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHGGRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIA
LGADTVLLGRAFLYALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPTALAPMAKGNAA
>SEQF1516_EDU87900.1 ATP synthase F1, gamma subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRPYAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLV
VSTDRGLCGGLNINLFKKLLAEMKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
DEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDTLLRRYVESQVYQGVVENLASEQ
AARMVAMKAATDNGGSLIKELQLVYNKARQASITQELTEIVSGAAAV
>SEQF1516_EDU87901.1 oligopeptidase A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNPLLTPFELPPFSKILPEHVVPAVTKALNDCRENVERVVAQGAPYTWENLCQPLAEVDDVLGRIFSPVSHLNSVKNSP
ELREAYEQTLPLLSEYSTWVGQHEGLYKAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIATRLS
ELGNQYSNNVLDATMGWTKLVTDEAELAGMPESALAAAKAQAEAKELEGYLLTLDIPSYLPVMTYCDNQVLREEMYRAYS
TRASDQGPNAGKWDNSKVMEEILALRHELAQLLGFENYAFKSLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFA
KAEFGVDELQPWDIAYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERKDVDVWHPDVRFFELYDEN
NELRGSFYLDLYARENKRGGAWMDDCVGQMRKADGSLQKPVAYLTCNFNRPVNGKPALFTHDEVITLFHEFGHGLHHMLT
RIETAGVSGISGVPWDAVELPSQFMENWCWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFR
LHAEFRPDQGAKILETLAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADAFSRFEEEGIFNRETGQ
SFLDNILSRGGSEEPMDLFKRFRGREPQLDAMLEHYGIKG
>SEQF1516_EDU87902.1 dipeptide ABC transporter, ATP-binding protein DppD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISE
KERRNLVGAEVAMIFQDPMTSLNPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQ
RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETGDAHA
IFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPGKYDRPNGCLLNPRCPYATDRCRAEEPALNMLADGRQSKCHYPLD
DAGRPTL
>SEQF1516_EDU87903.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTPGSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPPEM
ITADEMDAGLDAGRYTFAINIPPNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVS
LETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPFEIMMAKIWSMGLVVLVVSGLSL
VLMVKGVLGVPIEGSIPLFMLGVALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQDIML
IMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFFTIALLRFRKTIGTMA
>SEQF1516_EDU87904.1 hypothetical protein ECH7EC4501_0994 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHMCGGQKKADLPLKMQVAKVVKNAPGEAEDCPAMSV
>SEQF1516_EDU87905.1 site-specific recombinase, phage integrase family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPFMYIALCTHLYSMFRDALMPKLTDIQIRAWIKADERFDGKADGNGLYLCYPKNYTMPFWRFRYKFAGKQRAMVIGSYA
ELSLSRARETAKELSARVALGYDVAAEKQERKAEALAKMEAEKNAIRVSELAAEYFERQILPRWKHPDILRRRIDKDINP
RIGHMKAEDVKPRHIDEMLKAIVDRGAPTIATDVLRWTRRIFDYGIKRHVLEINPCSAFEVSDAGGKESSRDRWLTREEL
IRFFQAMRTAKGFSRQNELTFKLLLALCVRKMELCAARWEEFDLDNAVWHLPEERSKNGDPIDIPLVPPVIEWLKELRVL
SCNSAWVLPARKMQHRMIPHIQESTLPVALAKVRAEMPEVPDFTIHDFRRTARTHLAALGVDPVVAERCLNHRIKGVEGI
YNRYQYFDERTSALAKWTNLLVSLERGERYNVTPIRRAKA
>SEQF1516_EDU87906.1 thiosulfate sulfurtransferase glpE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAVQAFHLTNDTLGAFMRNNDFDTPVMVMCYHGNSSKGAAQYLLQ
QGYDVVYSIDGGFEAWQRQFPAEVAYGA
>SEQF1516_EDU87907.1 hypothetical protein ECH7EC4501_0788 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRISLPVWSQPGYELQLLQIKKLSWKASRNEEDCRVLTVKSNRKISGKPEGFR
>SEQF1516_EDU87908.1 tRNA guanosine-2'-O-methyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVGVHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIG
DAVAHLKGQGMQILATHLSDNAVDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE
AQRQRQNAGMYLRENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEADADWWATMQAAG
>SEQF1516_EDU87909.1 high-affinity branched-chain amino acid ABC transporter, periplasmic leucine-specific-binding protein LivK [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRNAKTIIAGMIALAISHTALADDIKVAVVGAMSGPIAQWGDMEFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQ
AVAVANKIVNDGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLDSSQGPTAAKYILETVK
PQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENIDFVYYGGYYPEMGQMLRQARSVG
LKTQFMGPEGVGNASLSNIAGDAAEGMLVTMPKRYDQDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSD
EPLALVKDLKANGANTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK
>SEQF1516_EDU87910.1 phosphate ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSMVETAPSKIQVRNLNFYYGKFHALKNINLDIAKNQVTAFIGPSGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNIL
TNSQDIALLRAKVGMVFQKPTPFPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ
RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARCSDHTAFMYLGELIEFSNTDDLF
TKPAKKQTEDYITGRYG
>SEQF1516_EDU87911.1 type III secretion apparatus lipoprotein, YscJ/HrcJ family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKHIKNLFLLAAICLTVACKEQLYTGLTEKEANQMQALLLSNDVNVSKEMDKSGNMTLSVEKEDFVRAITILNNNGFPK
KKFADIEVIFPPSQLVASPSQENAKINYLKEQDIERLLSKIPGVIDCSVSLNVNNNESQPSSAAVLVISSPEVNLAPSVI
QIKNLVKNSVDDLKLENISVVIKSSSGQDG
>SEQF1516_EDU87912.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLDYFALGVLIFVFLVIFYGIIILHDIPYLIAKKRNHPHADAIHVAGWVSLFTLHVIWPFLWIWATLYRPERGWGMQSH
DSSVMQLQQRIAGLEKQLADIKSSSAE
>SEQF1516_EDU87913.1 hypothetical protein ECH7EC4501_0771 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLICKKLALVCAVVVCWSTILKQCSIIFLSQNVFLKDSVVEWGNLPRPGGKVLPLRADNLCRVRAASLLNTGHL
>SEQF1516_EDU87914.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMGKAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR
>SEQF1516_EDU87915.1 protein-export chaperone SecB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQ
GGIFSIAGIEGTQMAHCLGAYCPNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA
>SEQF1516_EDU87916.1 hypothetical protein ECH7EC4501_0923 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEGVVSHEQAGHRASKNHRFVLFFSQGKNATGINPSSGGISRQHDEQAAQPDTASRRYYDFRNTFSKA
>SEQF1516_EDU87917.1 transcriptional regulator GadX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSLHGNCLIAYARHKYILTMVNGEYRYFNGGDLVFADASQIRVDKCVENFVLVSRDTLSLFLPMLKEEALNLHAHKKVS
SLLVHHCSRDIPVFQEVAQLSQNKNLRYAEMLRKRALIFALLSVFLEDDHFIPLLLNVLQPNMRTRVCTVINNNIAHEWT
LARIASELLMSPSLLKKKLREEETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGYHSVSYFIYVFRNYYGMTPTEYQ
ERSAQGLPNRDSAASIVAQGNFYGTDCSAEGIRL
>SEQF1516_EDU87918.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEYKDPMHELLSSLEQIVFKDETQKITLTHRTTSCTEIEQLRKGTGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKL
MRLIQANPALSKQLME
>SEQF1516_EDU87919.1 ATP synthase F1, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGLADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYA
DLAEGMKVKCTGRILEVPVGRGLLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGALANTIVVVATASESAALQYLAPY
AGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLLLRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGK
TGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGGIRTALAQY
RELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFAAERGYLADVELSKIGSFEAALLAYVDRDHA
PLMQEINQTGGYNDEIEGKLKGILDSFKATQSW
>SEQF1516_EDU87920.1 hemin transport protein HmuS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNHYTRWLELKEQNPGKYARDIAGLMNIREAELAFARVTHDAWRMHGDIREILAALESVGETKCICRNEYAVHEQVGTFT
NQHLNGHAGLILNPRALDLRLFLNQWASVFHIKENTARGERQSIQFFDHQGDALLKVYATDNTDMAAWSELLARFITDEN
TPLELKAVDAPVVQTRADATVVEQEWRAMTDVHQFFTLLKRHNLTRQQAFNLVADDLACKVSNSALAQILESAQQDGNEI
MVFVGNRGCVQIFTGVVEKVVPMKGWLNIFNPTFTLHLLEESIAEAWVTRKPTSDGYVTSLELFAHDGTQIAQLYGQRTE
GEQEQAQWRKQIASLIPEGVAA
>SEQF1516_EDU87921.1 acetylornithine/succinyldiaminopimelate aminotransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEYVDFAGGIAVTALGHCHPALVNALKTQGETLWHISNV
FTNEPALRLGRKLIEATFAERVVFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
FGPKPSDIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQHQALLVFDEVQCGMGRTGDLFA
YMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAFHPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVD
HLQKIDQQYDVFSDIRGMGLLIGAELKPQYKGQARDFLYAGAEAGVMVLNAGPDVMRFAPSLVVEDADIDEGMQRFAHAV
AKVVGA
>SEQF1516_EDU87922.1 AP endonuclease, family 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTGMFTCGHQRLPIEHAFRDASELGYDGIEIWGGRPHAFAPDLKAGGIKQIKALAQTYQMPIIGYTPETNGYPYNMMLG
DEHMRRESLDMIKLAMDMAKEMNAGYTLISAAHAGYLTPPNVIWGRLAENLSELCEYAENIGMDLILEPLTPYESNVVCN
ANDVLHALALVPSPRLFSMVDICAPYVQAEPVMSYFDKLGDKLRHLHIVDSDGASDTHYIPGEGKMPLRELMRDIIDRGY
EGYCTVELVTMYMNEPRLYARQALERFRALLPEDE
>SEQF1516_EDU87923.1 universal stress protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARYFSSLRALLVVLRNCDPLLYQYVDGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCG
LVVVSLIALMIWH
>SEQF1516_EDU87924.1 peptidase, S54 (rhomboid) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQAERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRR
YPFFAALRERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPALKFEFWRYFTHALMHFSLMHILFNLLWWWYLG
GAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWF
DLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
>SEQF1516_EDU87925.1 hypothetical protein ECH7EC4501_0954 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAALMVVENLNVFPYYLDGFIPVIKTIVSFFSVYYKFFIEVLS
>SEQF1516_EDU87926.1 putative DNA protecting protein DprA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLSANAQATLLLTSDFSRAAASKYKPLSNSEWGKFALWLKHQRISPAELLVPQPQEKLTGWSDPRISQERILGLLARGH
SLALAVDKWQRAGLWILTRGDADYPVRLKNRLRTDAPPVLFGCGNKALLQAEGMAIVGSRDAPTDDLRYTQQLAAKLAQQ
GICVISGGARGIDECAMASALEAGGTAVGVLADSLLKTSTLVKWREGLIAGNLVLISPFYPEVRFTVGNAMARNKYIYCL
AESAMVVRAGMTGGTITGAMEALKHQWLPVQVKPNQDMQSANSRLVENGASWSAEQAENVTIRLPDVPGLMYDRALRNAQ
PELFSLHEDDANYAVMPAYTPVDFYQLFVAELAILAKESISIERLASCTGLTIEQISVWLNRAEEEGRVIRLGEGHYQFR
>SEQF1516_EDU87927.1 DNA-3-methyladenine glycosylase I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MERCGWVSQDPLYIAYHDNEWGVPETDRKKLFEMICLEGQQAGLSWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLV
QDAGIIRHRGKIQAIIGNARAYLQMEQNGEPFADFVWSFVNHQPQVTQATTLSEIPTSTPASDALSKALKKRGFKFVGTT
ICYSFMQACGLVNDHVVGCCCYPGNKP
>SEQF1516_EDU87928.1 glycyl-tRNA synthetase, alpha subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMTCLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHY
YQFQVVIKPSPDNIQELYLGSLKELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVT
GEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDFLFTCFEQYEKEAQQLLALENPL
PLPAYERILKAAHSFNLLDARKAISVTERQRYILRIRTLTKAVAEAYYASREALGFPMCNKDK
>SEQF1516_EDU87929.1 ribonuclease PH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAK
GKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVA
AVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLLALARGGIESIVATQKAALAN
>SEQF1516_EDU87930.1 protein LpfD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKAAIALSLLGCVFGFSGKAFAGDAWGPCTPADGTTYHYNVDVDVGIPDAAKNVAGTVLPDVLNWSNGQNVSLICECPDS
YKNEKDTLVQGVSMLPPSGRTVDSMKYYTLTEELEVATNIRISTSVYGFVPFKNQQALQTTGCNKVITTPYMGGAGLLSF
AITKPFIGDSVIPLTLIAELYASKTNKDYGTIPISSVSIQGRVTVTQDCEIKPGTVLDVPFGEFPSSAFKNRQGQMPEGA
TEQEINLSFDCNNISDGIKVALRLEGATNADDPRAVDMGNPDIGVLVKDSSGKILVPNDSSSTTLLNLSSLDSKTHRNAA
IRLLALPISTTGKAPKGGTFEGVTTIYLEME
>SEQF1516_EDU87931.1 RNA methyltransferase, TrmH family, group 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRLRRAGLDYHEFTAVTRHHDFRAFLEAENPQRLFALTT
KGTPAHSAVNYQDGDYLMFGPETRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGALLRD
>SEQF1516_EDU87932.1 multidrug resistance protein MdtF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTITVSATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSS
TSDAAGNASITLTFETGTSPDIAQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS
NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQLGGMPQAADQQLNASIIVQTRL
QTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYSTVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPAS
LKTVYPYDTTPFIEISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINTLTMFGMVL
AIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLSAVFMPMAFMSGATGEIYRQFSITLISSMLL
SVFVAMSLTPALCATILKAAPEGGHKPNALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVIYLLICAGMAVLFLRTPTS
FLPEEDQGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKDNVQSVFTVGGFGFSGQGQNNGLAFISLKPWSERVGEEN
SVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMELLDNGNLGHEKLTQARNELLSLAAQSPNQVTGVRPNGLE
DTPMFKVNVNAAKAEAMGVALSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAPLS
AYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYSWTGLSYQEALSSNQAPALYAISLV
VVFLALAALYESWSIPFSVMLVVPLGVVGALLATDLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTPIE
AIIEAARMRLRPILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIYFVPVFFVVVEHLFARFKKA
>SEQF1516_EDU87933.1 AsmA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKAGKITAAISGAFLLLIVVAIILIATFDWNRLKPTINQKVSAELNRPFAIRGDLGVVWERQKQETGWRSWVPWPHVHA
EDIILGNPPDIPEVTMVHLPRVEATLAPLALLTKTVWLPWIKLEKPDARLIRLSEKNNNWTFNLANDDNKDANAKPSAWS
FRLDNILFDQGRIAIDDKVSKADLEIFVDPLGKPLPFSEVTGSKGKADKEKVGDYVFGLKAQGRYNGEPLTGTGKIGGML
ALRGEGTPFPVQADFRSGNTRVAFDGVVNDPMKMGGVDLRLKFSGDSLGDLYELTGVLLPDTPPFETDGRLVAKIDTEKS
SVFDYRGFNGRIGDSDIHGSLVYTTGKPRPKLEGDVESRQLRLADLGPLIGVDSGKGAEKSKRSEQKKGEKSVQPAGKVL
PYDRFETDKWDVMDADVRFKGRRIEHGSSLPISDLSTHIILKNADLRLQPLKFGIAGGSIAANIHLEGDKKPMQGRADIQ
ARRLKLKELMPDVELMQKTLGEMNGDAELRGSGNSVAALLGNSNGNLKLLMNDGLVSRNLMEIVGLNVGNYIVGAIFGDD
EVRVNCAAANLNIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSPLYVRGTFKNPQAGVKA
GPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILSQMKK
>SEQF1516_EDU87934.1 conserved hypothetical protein TIGR00255 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRSLEPVVRERIRSRLTRGKVECTLRYEPDVSAQGELIL
NEKLAKQLVTAANWVKMQSDEGEINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIVARETEGQALKALIEQRL
EGVTAEVVKVRAHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVLLAQRIDVAEELDRLEAHVKETYNILKKKEAVGR
RLDFMMQEFNRESNTLASKSINAEVTNSAIELKVLIEQMREQIQNVE
>SEQF1516_EDU87935.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRLLILTALLPFVGFAQPINTLNNPNQPGYQIPSQQRMQTQMQTQQIQQKGMLNQQLKTQTQLQQQHLENQINNNSQRV
LQSQPGERNPARQQMLPNTNGGMLNSNRNPDSSLNQQHMLPERRNGDMLNQPGTPQPDIPLKTIGP
>SEQF1516_EDU87936.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVKRWLLAGIALCLLTGMRDPFKPPEDLCRISELSQWRYQGMVGRGERIIGVIKDGQKKWRRVQQNDVLENGWTILQLT
LDVLTLGTGTNCEPPQWLWQRQGDTNEAMDSRTTVDADTRRTGGKAAKSDADGG
>SEQF1516_EDU87937.1 heat shock protein 15 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSKPSKIVELNATLTLRQGNDERTVIVKAITEQRRPASE
AALLYEETAESVEKREKMALARKLNALTMPHPDRRPDKKERRDLLRFKHGDSE
>SEQF1516_EDU87938.1 cell filamentation protein Fic [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRAATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREV
DIYQGDTPFCHFAYIEKEGNALMQDLEEEGYLVGLEKTKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE
>SEQF1516_EDU87939.1 hypothetical protein ECH7EC4501_0641 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHRIVLTTLQNPGSVHQHATGASEEACKKAGFKDAVEL
>SEQF1516_EDU87940.1 alternative sigma factor RpoH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYHGDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQ
EGNIGLMKAVRRFNPEVGVRLVSFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE
LGVTSKDVREMESRMAAQDMTFDLSSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWEEQAANRLTDAMQGLDERSQDII
RARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMKKLRAAIEA
>SEQF1516_EDU87941.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMAGTVLYQDRAMKQITFAPRNHLLTNTNTWTPDSQWPVFDVRPSGASFTGETIERVNIHTGEVEVIYRVSQGAHVGVVT
VHPKSEKYVFIHGPENPHETWHYDFHHRRGVIVEGGKMNNLDAMDITVPYTSGALRGGSHVHVFSPNGEMVSFTYNDHVM
HQFDSALDLRNVGVAAPFGPVNVQKQHPREYSGSHWCVLVSKTTPTPQPGSDEINRAYEEGWVGNHALAFIGDTLSPKGE
KVPELFIVELPQDEAGWKAAGDAPLSGTETTLPAPPRGIVQRRLTFTHHRAYPGLVNVPRHWVRCNPQGTQIAFLMRDDN
GIVQLWLISPQGGEPRQLTHNKTDIQSAFNWHPSGEWLGFVLGNRIACAHAQSGEVEYLTENHANPPSADAVVFSPDGQW
LAWMEGGQLWITETDR
>SEQF1516_EDU87942.1 putative 3-oxoacyl-(acyl-carrier-protein) reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRSVLVTGASKGIGRAIACQLAADGFNIGVHYHRDATGAQETLNAIVANGGNGRLLSFDVANREQCREVLEHEIAQHGA
WYGVVSNAGIARDAAFPALSDDDWDAVIHTNLDSFYNVIQPCIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGI
IGATKALAIELAKRKITVNCIAPGLIDTGMIEMEESALKEAMSMIPMKRMGQAEEVAGLASYLMSDIAGYVTRQVISING
GML
>SEQF1516_EDU87943.1 transcriptional regulator, GntR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIYKSIAERLRIRLNSADFTLNSLLPGEKKLAEEFAVSRMTIRKAIDLLVAWGLVVRRHGSGTYLVRKDVLHQTASLTGL
VEVLKRQGKTVTSQVLIFEIMPAPPAIASQLRIQINEQIYFSRRVRFVEGKPLMLEDSYMPVKLFRNLSLQHLEGSKFEY
IEQECGILIGGNYESLTPVLADRLLARQMKVAEHTPLLRITSLSYSESGEFLNYSVMFRNASEYQVEYHLRRLHPDKS
>SEQF1516_EDU87944.1 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAKAFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGK
WADLVILAPATADLIARVAAGMANDLVSTICLATPAPVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGD
IGPGRMLDPLTIVDMAVAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGFAIAAAAARRGANVTLVSGPVSL
PTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAAVADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDH
RPYVVGFAAETNNVEEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLLLDEIVTRY
DEKNRR
>SEQF1516_EDU87945.1 acetyltransferase, gnat family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGITAPTPLTSEHNLADFCCSDHGMNEWLKKKALKNHSSGLSRVYVICIANTRQVIGYYCLSTGSIQRNLAPGAMRRNAP
ESLPVVVLGRLAIDQAWAGKGLGVALLKDAVYRTMSIAQQVGVRALIVHALDDSVRNFYLKYAFVPSPFQSLTLLYPITL
E
>SEQF1516_EDU87946.1 mannitol operon repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRSFLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLL
DGDGPLGDLSVRLKLIYGLGVINRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
YAMQIQRYQQAVRSTMVLSLTELISRISLKKAFQK
>SEQF1516_EDU87947.1 hypothetical protein ECH7EC4501_0969 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGIAITSLFGYSLQELVSQFAMINHKVRLHGHEPHTRGSRTRLHCSSGNRRFKRLCSRLN
>SEQF1516_EDU87948.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPTTTTTRTTTTAADGAVGSSFALSMEVAIGDLVGFVFNNIYTSTALQGRQWKIFQQGKIEGLITFCTVLQVTKNPAGAR
FRQPPAAGNRKAHCIMSTQKVYVFRAKRAISARILTYLVHS
>SEQF1516_EDU87949.1 selenocysteine-specific translation elongation factor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAYWPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALL
VVACDDGVMAQTREHLAILQLTGNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFITAATEGRGIDALREH
LLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRVRALHAQNQPTETANAGQRIALN
IAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHTPLTQWQPLHIHHAASHVTGRVSLLEDNLAELVFDPPLWLADNDR
LVLRDISARNTLAGARVVMLNPPRRGKRKPEYLQCLASLARAQNDSEALAVHLQRGAVNLPDFAWARQLNGEGMRELLQQ
PGYIQAGYSLLNAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMALPMEDEALVLLLIEKMRESGDILSHHGWLHL
PDHKAGFSEEQQAIWQKAEPLFGDEPWWVRDLAKETGTDEQAMRLTLRQAAQQGIITAIVKDRYYRNDRIVEFANMIRDL
DQECGSTCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRGNDHLLRDALLFPEK
>SEQF1516_EDU87950.1 DamX protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDEFKPEDELKPDPSDRRTGRSRQSSERSERTERGEPQINFDDIELDDTDDRRPTRAQKERNEEPEIEEEIDESEDETVD
EERVERRPRKRKKAASKPASRQYMMMGVGILVLLLLIIGIGSALKAPSTTSSDQTASGEKSIDLAGNATDQANGVQPAPG
TTSAENTQQDVSLPPISSTPTQGQTPAATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPATVAPVRNGNASR
DTAKTQTAERPATTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAATSTPAPKETATTAPVQTASP
AQTTATPAAGGKTAGNVGSLKSAPSSHYTLQLSSSSNYDNLNGWAKKENLKNYVVYETTRNGQPWYVLVSGVYASKEEAK
KAVSTLPADVQAKNPWAKPLRQVQADLK
>SEQF1516_EDU87951.1 Rhs family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVTFGHPVNPLLGAKVLPGETDIALPGPLPFILSRTYSS
YRTKTPAPVGSLGPGWKMPADIRLQLRDNTLILSDNGGRSLYFEHLFPGEDGYSRSESLWLVRGGVAKLDEGHRLAALWQ
ALPEELRLSPHRYLATNSPQGPWWLLGWCERVPEADEVLPAPLPPYRVLTGLVDRFGRTQTFHREAAGEFSGEITGVTDG
AGRHFRLVLTTQAQRAEEARQQAISGGTEPSAFPDTLPGYTEYGRDNGIRLSAVWLTHDPEYPENLPAAPLVRYGWTPRG
ELAVVYDRSGKQVRSFTYDDKYRGRMVAHRHTGRPEIRYRYDSDGRVTEQLNPAGLSYTYQYEKDRITITDSLNRREVLH
TQGEGGLKRVVKKEHADGSVTQSQFDAVGRLRAQTDAAGRTTEYSPDVVTGLITRITTPDGRASAFYYNHHSQLTSATGP
DGLEIRREYDEWGRLIQETAPDGDITRYRYDNPHSDLPCATEDATGSRKTMTWSRYGQLLSFTDCSGYVTRYDHDRFGQM
TAVHREEGLSQYRAYDSRGQLIAVKDTQGHETRYEYNAAGDLTTVIAPDGSRNGTQYDAWGKAICTTQGGLTRSMEYDAA
GRVIRLTSENGSHTTFRYDVLDRLIQETGFDGRTQRYHHDLTGKLIRSEDEGLVTHWHYDEADRLTHRTVKGETAERWQY
DERGWLTDISHISEGHRVTVHYGYDEKGRLTGERQTVHHPQTEALLWQHETRHAYNAQGLANRCIPDSLPAVEWLTYGSG
WLAGMKLGDTPLVDFTRDRLHRKTLRRFGRYELTTAYTPAGQLQSQHLNSLQYDRDYTWNDNGELIRISSPRQTRSYSYS
DSGRLTGVHTTAANLDIRIPYATDPAGNRLPDPELHPDSTLSMWPDNRIARDAHYLYRYDRHGRLTEKTDLIPEGVIRTD
DERTHRYHYDSQHRLVHYTRTQYEEPLVESRYLYDPLGRRVAKRVWRRERDLTGWMSLSRKPQVTWYGWDGDRLTTIQND
RTRIQTIYQPGSFTPLIRVETATGELAKTQRRSLADALQQSGGEDGGSVVFPPVLVQMLDRLESEILADRVSEESRRWLA
SCGLTVAQMQSQMDPVYTPARKIHLYHCDHRGLPLALISAEGATEWCAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEES
GLYYNRHRYYDPLHGRYITQDPIGLKGGWNFYQYPLNPVINVDPQGLVDINLYPESDLIHSVADEINIPGVFTIGGHGTP
TSIESATRSIMTAKDLAYLIKFDGNYKDGMTVWLFSCNTGKGQNSFASQLAKELHTNVIGPDTLWTWWGRGTNGKLKMDT
VLTAPTNLNSNKDLMAITTKDLGNWITYGPSGHPISNMQGTPEKPSDIR
>SEQF1516_EDU87952.1 sugar transporter, glycoside-pentoside-hexuronide family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSTPITTADIAKGKIDDALSVREKIGYGLGDAGGTVITCLIMNFLTFFYTDVFGLTPALVGTLFIALRVFDAISDPVMG
VIADRTQSRWGRFRPWQLWIAIPIGIIGILTFTVPDASMGVKIAWAFGTYLLLSVGYTAINVPYCARINTMTTRHNEVIS
CQSWRFVLCGVAGFLVSVGLPWMVALFGQGNAARGYQLGVGVLCAIAVVMFLCCFFWVRERVPLSTMGKFTLREHLAGLR
NNDQLLLMLVMSFLLINVFNIRGGGYMYFITYVLQGSTGYTSLFFTMVTFASIIGSVIVSPLTRRFDTVKIYYYTNLLLA
ALAVLMWFLPSGPAYQTLWLAVILGNGVILGFTLPLHFSLMAFADDYGEWKTHVRSSGMNFAFNLFFIKLAWASSAGIIS
LLFIFVAYQPGVENQTASSLGGIAAMETLLPALFHLLLAGAIRFCKLNNPMMSRIATDLRQRHVQP
>SEQF1516_EDU87953.1 nickel ABC transporter, periplasmic nickel-binding protein NikA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSTLRRTLFALLACASFIVHAAAPDEITTAWPVNVGPLNPHLYTPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSE
DGKTWTFTLRDDVKFSNGEPFDAEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRP
FRFIAPSQFKNHETMNGIKAPIGTGPWVLQESKLNQYDVFVRNENYWGEKPAIKKITFNVIPDPTTRAVAFETGDIDLLY
GNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALNTAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSV
PYANLGLKPRQYDPQKAKALLEKAGWTLPAGKDIREKNGQPLHIELSFIGTDALSKSMAEIIQADMRQIGADVSLIGEEE
SSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADKPLIDKEIGEVLATHDEAQRQALYRDILTRL
HDEAVYLPISYISMMVVSKPELGNIPYAPIATEIPFEQIKPVKP
>SEQF1516_EDU87954.1 transcription elongation factor GreB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTPLVTREGYEKLKQELNYLWREERPEVTKKVTWAASLGDRSENADYQYNKKRLREIDRRVRYLTKCMENLKIVDYSPQ
QEGKVFFGAWVEIENDDGVTHRFRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPAGEASWYVNAIEYVKP
>SEQF1516_EDU87955.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIGTVAGTNDSTTTIATNDMVQEHVTNFTKELFGYIANGIGDDISSIARTMLGEVLEKVDDWQIERFQQSIQDDKISFT
IQTDYSEKYSMLSGMRAHILRRNNHYQFIVTINSKNYGCPLDNTDINWCGIVYLLNNMTVNDNANDVAVTESYKPIWNWK
ISQYNVSDIKFETIIKPQFADRIYFSNCSPVDPTSTRPTYFGDTDGSVGAVLYALFATGHLGIMAEGENFLSQLLNIEDE
VLNVLLRENFNEQVDTNVNTIISILNRRDIILESLQPYLVINKDAVTPCTFLGDQTGDRFSNICGDQFIIDLLKRIMSIN
DNVHVLAGNHETNCNGNYMQNFTRMKPLDEDTYDGIKDYPVCFYDSKYKIMANHHGITFDDQRKRYIIGPITVSIDEMTN
ALDPVELAAIINKKHHTIINSKKFKTSRAISCRSFNRYFSVSTDYRPKLEALLACSQMLGINQVVAHNGNGGRECIGETG
TVLGLNARDSKHTGRMFSMHNCQINPSAGPEITTPWKSYQHEKNRNGLMPLIRRRTMLQL
>SEQF1516_EDU87956.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQQITLAEASLQAQQVEVISRMIERNHEEIDDHNLSVIAGLIKQLSSNVAVWLMTEEEKRGEQ
>SEQF1516_EDU87957.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNLVKYVGIGLLVMGLAACDDKDTNATAQGSVAESNATGNPVNLLDGKLSFSLPADMTDQSGKLGTQANNMHVWSDATG
QKAVIVIMGDDPKEDLAVLAKRLEDQQRSRDPQLQVVTNKAIELKGHKMQQLDSIISAKGQTAYSSVILGNVGNQLLTMQ
ITLPADDQQKAQTTAENIINTLVIQ
>SEQF1516_EDU87958.1 transcriptional regulator DctR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLIITRDTMFFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVIIDTLMNNVFHSNFLTQIERLKPVHVIIFSPFNIKRC
LGKVPVTFVPRTITIIDFVALINGSYCSVPEANVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNL
KRINELVRHQHIDYLV
>SEQF1516_EDU87959.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATGKSCSRWFAPLAALLMVVSLSGCFDKEGDQRKAFIDFLQNTVMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQV
NQAMDSGLRPVVDSVNAIRVPQDYVTQSGPLREMNGSLGVLAQQLQNAKLQADAAHSALKQSDDLKPVFDQAFTKVVTTP
ADALQPLIPAAQTFTQQLVMVGDYIAQQGTQVSFVANGIQFPTSQQASEYNKLIAPLPAQHQAFNQAWTTAVTATQ
>SEQF1516_EDU87960.1 IS911 transposase orfA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKKTKRTFTPEFRLECAQLIVDKGYSYRQASEAMNVGSTTLESWVRQLRRERQGIAPSATPITPDQQRIRELEKQVRRL
EEHNTILKKATTALLMSDSLNGSR
>SEQF1516_EDU87961.1 membrane-associated sulfatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWKGISAVVELAATVLVTFFLLRLLSLFGRRSWRILASL
VVLFSAGASYYMTFLNVVIGYGIIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRS
LAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAWARVDESSDNNSLLNPAKKFTYQ
APQNVNDTYVVFIIGETTRWDHMGIFGYERNTTPKLAQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQN
IFAVLKQLGFSSDLYAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLIILHTKGSH
FNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVIDQVRDKKAIVFYAADHGESINEREHLHGTPR
ELAPPEQFRVPMMVWMSDKYLENPVNAQAFAQLKKAADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQTKEA
AAN
>SEQF1516_EDU87962.1 dipeptide ABC transporter, permease protein DppC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLFIAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHL
LGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAPLIVQASLGFSNAILDMAALGFL
GMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAILLTVLAFNLMGDGLRDALDPKLKQ
>SEQF1516_EDU87963.1 type III secretion apparatus domain protein, YscI/HrpB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNINQSENINIQLNKAPQTNFVDEHTSLASAPSAAGAAQFLDQLLPKTAGVSSPEQVLIEEIKKRHLATMNSDLSFDAL
SAGGLSPEDVLTLQKNVLNANVNVDVVSKLASLLSTSVTKLVSMQ
>SEQF1516_EDU87964.1 high-affinity branched-chain amino acid transport system permease protein livH [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHGEVYMIGSYVSFMIIAALMMMGIDTGWLLVAAGFVGA
IVIASAYGWSIERVAYRPVRNSKRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWVVGHSENFSASITTMQAVI
WIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAVAGVLLGQFYGVINPYIGFMAGM
KAFTAAVLGGIGSIPGAMIGGLILGIAEALSSAYLSTEYKDVVSFALLILVLLVMPTGILGRPEVEKV
>SEQF1516_EDU87965.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKLQLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADFESKVGLKVFDRTTRQLMLTLFGTALLPYINDMLDRN
EQLNNFIADYKHEKRGRVTIYAPTGIITYLSKHVIDKIKDIGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDE
SLVASFITQYAVTAYASQRYLEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGSKEVRDYRVKGNYVCDNTQSALE
LARNHLGIVFAPDKSVQSDLQDGTLVPCFQHPYEWWLDLVAIFRKREYQPWRVQYVLDEMLREIRHQLAQSQQLRPEQAA
ESED
>SEQF1516_EDU87966.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANLCPSTFLDKNRNVAAELDIKNNEKKYSPGSNFAKWMLQEIKRLILNIMSGSRSINTDILDYFHPMPGTENNGNRTWV
AATGEDEYIEIKQTGDKSFNITLVGRDKPSRKEIPYSGVAVATIIKSLSEKTSALETHSADTVLRKKLVNSIVMKNTDFN
YEIPAGILSNIYDLLKLRIKKDEGYVPVQESFKRTDVFFDSMIMDAH
>SEQF1516_EDU87967.1 PEP-dependent sugar transporting PTS family, IIC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDIAHTLYNIVQYILGFGPTVMLPLVLFILALCFKVKPAKALRSSLTVGIGFVGIYAIFDILTSNVGPAAQAMVERTGI
NLPVVDLGWPPLSAITWGSPIAPFVIPLTILINVAMLALNKTRTVDVDMWNYWHFALAGTLVYYSTGSLFFGLLAAAIAA
VVVLKLADWSAPLVQKYFGLEGISLPTLSSVVFFPVGLLVDKIIDHIPGLNRIHIDPETVQKKFGIFGEPMMVGTILGIL
LGVIAGYDFKKVLLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNAKYPDRDDLYIGLDIAVAVGNPAIISTALLL
TPISVFIAFVLPGNEVLPLGDLANLAVMASMIALASRGNIFRTVLAAIPVIIADLWIATKIAPFITGMAKDVNFKFAEGS
SGQVSSFLDGGNPFRFWLLEIFNGNLIAIGLVPVIALVLYGIFRMTRSTVYA
>SEQF1516_EDU87968.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMFFDWWFATSPRLRQFCWAFWLLMLVTLIFLSSTHHEERDALIRLRASHHQHWATLYRLVDTTPFSEEKTLPFSPLDF
QLPGAQLVFWHPSAQGGELALKTLWEAVPSAFTRLAERNVSVSRFSLSVEGDDLLFTLQLETPHEG
>SEQF1516_EDU87969.1 glutathione-disulfide reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVNVGCVPKKVMWHAAQIREAIHMYGPDYGFDTTINKFN
WETLIASRTAYIDRIHTSYENVLGKNNVDVIKGFARFVDAKTLEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGF
FALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVMNAEGPQLHTNAIPKAVVKNADG
SLTLELEDGRSETVDCLIWAIGREPANDNINLEAAGVKTNEKGYIVVDKYQNTNVEGIYAVGDNTGAVELTPVAVAAGRR
LSERLFNNKPDEHLDYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMKLVCVGPEE
KIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR
>SEQF1516_EDU87970.1 universal stress protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYP
ITETLSGSGDLGQVLVDAIKKYDMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE
>SEQF1516_EDU87971.1 guanylate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGN
YYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRDQDSEEVIAKRMAQAVAEMSHY
AEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD
>SEQF1516_EDU87972.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNVELSPATRWGMIATGLLQGLVCYLLIAWLSGKNHSWIVYGVPATVAFSSVLLFSVISFKQKRLWGWLALVFIATLGM
SGWLKWQTDGMTPWRAEKALWDFGCYLLLMAMLLLPWIQQSLRIRNDSSRYRYFYQSVWHNVLILLVIFLANGLTWLVLL
LWSELFKLVGITFFKTLFFATDWFIYLTLGLVTALAVILARTQSRLIDSIQKLFTLIATGLLPLVSLLTLMFIITLPFTG
LSAISRHISAAGLLLTLAFLQLILMAIVRDPQKASLPWTGPLRCLIKTALLVAPLYVFIAAWALWLRVAQYGWTVDRLQG
ALAVLVLLVWSLGYFVSIVWRKGQNPLVLQGKVNLAVSLLVLVILVLLNSPVLDSMRISVNSHMARYQSGKNTPDQVTIY
MLEHSGRYGRAALESLKSDAEYMKDPKRARDLLMALDGEQHLQQQISEKVLAENVLIAPGSGKPDATFWSALIQDRYNVM
TCIEKDACVLVEQDLNSDGRAERILFAFDDERYIVYGFDPDKKEWQELTMSLLPRDITKEKLLTAAKDGKLGTKPKAWRD
LVVDGERLDVNLNE
>SEQF1516_EDU87973.1 DNA utilization protein YhiR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAGAGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEP
YINVVKHFNRSGQLRYYPGSPLIARQLLREQDSLQLTELHPSDYPLLRSEFQKDSRARVEKSDGFQQLKAKLPPVSRRGL
ILIDPPYEMKTDYQAVVSGIAEGYKRFATGTYALWYPVVLRQQIKRMIHDLEATGIRKILQIELAVLPDSDRRGMTASGM
IVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSWIVPE
>SEQF1516_EDU87974.1 EspF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAAYEKSKGPEALGFKPARQAPPPPTSGQASGASRPLPPIAQALKEHLAAYEKSKGPEALGFKPARQAPPPPTSGQASGA
SRPLPPIAQALKEHLAAYEKSKGPEALGFKPARQAPPPPTGPSGLPPLAQALKDHLAAYEQSKKG
>SEQF1516_EDU87975.1 integrase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGVSGWLLAEIPPGGWIHQKLEDVMALTDVKVKTAKPKERPYKLADGGGMYLLINANGSKYWRMKYRFAGKEKMLSIGVY
PDVTLADAREKRSEARKILAAGGDPGEAKKEEKIALQMSLKNTFEAVAREWHQTKADRWSLRYRDEIIDTFEKDIFPYIG
KRPIAEIKPMELLEALRKMEKRGALEKMRKVRQRCGEVFRYAIVTGRADYNPAPDLASALATPKKVHFPFLTANELPHFL
TDLAGYTGSIITKTATQIIMLTGVRTQELRFAHWEDIDFEAKLWEIPAEVMKMKRPHIVPPSEQVIALFKQLEPISKHHP
LVFIGRNDPRKPISKESINQVIELLGYKGRLTGHGFRHTMSTILHEQGFNSAWIEMQLAHVDKNSIRGTYNHAQYLDGRR
EMMQWYADYIDSLSELA
>SEQF1516_EDU87976.1 cell division protein FtsX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKRDAINHIRQFGGRLDRFRKSVGGSGNGGRNAPKRAKSSPKPVNRKTNVFNEQVRYAFHGALQDLKSKPFATFLTVMV
IAISLTLPSVCYMVYKNVNQAATQYYPSPQITVYLQKTLDDDAAAGVVAQLQAEQGVEKVNYLSREDALGEFRNWSGFGG
ALDMLEENPLPAVAVVIPKLDFQGTESLNTLRDRITQINGIDEVRMDDSWFARLAALTGLVGRVSAMIGVLMVAAVFLVI
GNSVRLSIFARRDSINVQKLIGATDGFILRPFLYGGALLGFSGALLSLILSEILVLRLSSAVAEVAQVFGTKFDINGLSF
DECLLLLLVCSMIGWVAAWLATVQHLRHFTPE
>SEQF1516_EDU87977.1 protein GntY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYCPPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDF
VTDQLGSQLTLKAPNAKMRKVADDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLK
EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY
>SEQF1516_EDU87978.1 inorganic anion transporter, sulfate permease (SulP) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVYIVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGL
FANLPVALAPAMGLNAFFAFVVVQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
LKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLGWMLGDVHYNGIVSAPPSVMTVV
GHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVTDKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESS
SGVSVGGRTGLTAVVVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAVMMPFSFSI
TEGIALGFISYCVMKIGTGRIRDLSPCVIIVALLFILKIVFIDAH
>SEQF1516_EDU87979.1 polysaccharide deacetylase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFPFRRNVLAFAALLALSSPVLAGKLAIVIDDFGYRPHNENQVLAMPSAISVAVLPDSPHAREMATKAHNSGHEVLIHLP
MAPLSKQPLEKNTLRPEMSSDEIERIIRSAVNNVPYAVGINNHMGSKMTSNLFGMQKVMQALERYNLYFLDSVTIGNTQA
MRAAQGTGVKVIKRKVFLDDSQNEADIRVQFNRAIDLARRNGSTIAIGHPHPSTVRVLQQMVYNLPPDITLVKASSLLNE
PQVDTSTPPKNAVPDAPRNPFRGVKLCKPKKPIEPVYANRFFEVLSESISQSTLIVYFQHQWQGWGKQPEAAKFNASAN
>SEQF1516_EDU87980.1 nitrite reductase [NAD(P)H], small subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQWKDICKIDDILPETGVCALLGDEQVAIFRPYHSDQVFAISNIDPFFESSVLSRGLIAEHQGELWVASPLKKQRFRLS
DGLCMEDEQFSVKHYEARVKDGVVQLRG
>SEQF1516_EDU87981.1 sn-glycerol-3-phosphate transport system permease protein UgpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSSRPVFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSVDPFGFSSRFVGLDNFVALFHDSYYIDSFWTTIKFST
FVTVSGLLVSLFFAALVEYIVRGSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFL
VVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFLLVVNLVYAFFDTFPVIDAATSG
GPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFLVIVLTVMQFRYVESKVRYQ
>SEQF1516_EDU87982.1 xylose isomerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRFAACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAK
RKADVAFEFFHKLHVPFYCFHDVDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVEHKHKIGFQGTLLIEPKPQEPTK
HQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAGHSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENAL
VMYEILKAGGFTTGGLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAACMIEDGELDKRIAQRYSGWNSELGQQILK
GQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK
>SEQF1516_EDU87983.1 ATP synthase F1, delta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQMAELLSGALAPETLAESFIAVCGEQLDENGQNLIRVM
AENGRLNALPDVLEQFIHLRAVSEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
DGSVRGRLERLADVLQS
>SEQF1516_EDU87984.1 fimbrial family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKWHYIFCIILFHLGLPCGYAANDGTCATRGGTHTLSLNFPLTTVSAANNVPGNTLIDIANATSSENYSVLCNCDSKHS
NGAYHEIYYTADPAPGMVYSTTASGLAFYYLNEYVDVGTKISVLNAGYTAVPFEHVSNQATTTDHTCQGNKTTAVGVSLK
TGADAKISFRIKRSINGTVVIPITDIALLYANISSTTTRGEAIAKVRISGSLTAPQSCQINAGQVIYFDFDTIPASEFSS
TAGQAITSRKITKTVSIECTGMGYERTQKVDASFTGTNRSSDDTMVATDNADVGIKIYNKSNAEVSVNNGKLPADMGNTT
IFGRKNGSVTFSAAPASFTGARPQPGVFNATATLTIEFVN
>SEQF1516_EDU87985.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLYEFKNIKIDLVLTEDIIPEDKLQEIIQSDDIIKLARKKTYEHLLRARRKSKELKTESRKKIARKMILMRERIRKNNK
IKLDKEVNQSIKWVKDIQAIELVLMQDIMNKIHLSLTNALHSLDTSSRINWDDLLNEVVRETLSNNNIVGAIKITKNPDI
KLDPGEANNIQLINDANTPHNKIIIENEYIRITLDPLEQISILLNSFKDNYLSIIQE
>SEQF1516_EDU87986.1 maltodextrin phosphorylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQPIFNDKQFQEALSRQWQRYGLNSAAEMTPRQWWLAVSEALAEMLRAQPFAKPVANQRHVNYISMEFLIGRLTGNNLL
NLGWYQDVQDSLKAYDINLTDLLEEEIDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVDGKQVEAPD
DWHRSNYPWFRHNEALDVQVGIGGKVTKDGRWEPEFTITGQAWDLPVVGYRNGVAQPLRLWQATHAHPFDLTKFNDGDFL
RAEQQGINAEKLTKVLYPNDNHTAGKKLRLMQQYFQCACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLR
VLIDEHQMSWDDAWAITSKTFAYTNHTLMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEKVWAKLAVV
HDKQVHMANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTNGITPRRWIKQCNPALAALLDKSLKKEWAND
LDQLINLEKFADDAKFRQQYREIKQANKVRLAEFVKVRTGIEINPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENP
QADRVPRVFLFGAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIPAADISEQISTAGKEAS
GTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVEQVKAILAKGYDPVKWRKKDKVLDAVLKELESGKYSDGD
KHAFDQMLHSIGKQGGDPYLVMADFAAYVEAQKQVDVLYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR
>SEQF1516_EDU87987.1 putative Mg2+ transporter-C (MgtC) family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHFYMTAEFIIRLILAAIACGAIGMERQMRGKGAGLRTHVLIGMGSALFMIVSKYGFADVLSLDHVGLDPSRIAAQVVTG
VGFIGAGNILVRNQNIVGLTTAADIWVTAAIGMVIGSGMYELGIYGSVMTLLVLEVFHQLTFRLMNKNYHLQLTLVNGNT
VSMLDWFKQQKIKTDLVSLQENEDHEVVAIDIQLHATTSIEDLLRLLKGMAGVKGVSIS
>SEQF1516_EDU87988.1 high-affinity branched-chain amino acid ABC transporter, permease protein LivM [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPMHIAMALLSAAMFFVLAGVFMGVQLELDGTKLVVDTASDIRWQWVFIGTAVVFFFQLLRPAFQKGLKSVSGPKFILP
AIDGSTVKQKLFLVALLVLAVAWPFMVSRGTVDIATLTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYY
GLGFWTCLPIAGLMAAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGGPNGISQIPKPTFFGLEFSRTAR
EGGWDTFSNFFGLKYDPSDRVIFLYLVALLLVVLSLFVINRLLRMPLGRAWEALREDEIACRSLGLSPRRIKLTAFTISA
AFAGFAGTLFAARQGFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAILLVVSRELMRDFNEYSMLMLGGLMVLMMIW
RPQGLLPMTRPQLKLKNGAAKGEQA
>SEQF1516_EDU87989.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKSITTLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLAKLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQ
MSNLLLDKPHHQTPRGLKFELAAESPLMMIMLNALSKQIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSR
ELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHEKWDLDTFLRYPHISICWEQSDTWALDNVLQELGRERTIAMSLPEFEQ
SLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPLPFDESQQKKLEVPFTLLWHKRNSHNPKIVWLRDTIKNLYASMA
>SEQF1516_EDU87990.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIWIMLATLAVVFVVGFRVLTSGARKAIRRLSDRLNIDVVPVESMVDQMGKSAGDEFLRYLHRPDESHLQNAAQVLLIWQ
IVIVDGSEQNLLQWHRILQKARLAAPITDAQVRLALGFLRETEPEMQDINAFQMRYNAFFQPAEGVHWLH
>SEQF1516_EDU87991.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQSKEKKKLSLLTTKFSDEAWGDNHKNKVVYRAQDRFHNPLFIVLMVVKKKLDHKKLIDNNSHYHVCI
>SEQF1516_EDU87992.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLKTFRVFSRAVNKRGHTIGITQNVKAENVQAAISTVINKSAKAGLSGVIIHAVTCIQDEE
>SEQF1516_EDU87993.1 EspG protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MINGLNNDSASLVLDAAMKVNSGFKKSWDEMSCAEKLFKVLSFGLWNPTYSRSERQSFQELLTVLEPVYPLPNELGRVSA
RFSDGSSLRISVTNSELVEAEIRTANNEKITVLLESNEQNRLLQSLPIDRHMPYIQVHRALSEMDLTDTTSMRNLLGFTS
KLSTTLIPHNAQTDPLSGPTPFSSIFMDTCRGLGNAKLSLNGVDIPANAQKLLRDALGLKDTHSSPTRNVIDHGISRHDA
EQIARESSGSDKQKAEVVEFLCHPEAATAICSAFYQSFNVPALTLTHERISKASEYNAERSLDTPNACINISISQSSDGN
IYVTSHTGVLIMAPEDRPNEMGMLTNRTSYEVPQGVKCIIDEMVSALQPRYAASETYLQNT
>SEQF1516_EDU87994.1 sigma-54 dependent transcriptional regulator RtcR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRKTVAFGFVGTVLDYAGRGSQRWSKWRPSLCICQQESLVIDRLELLHDARSRSLFETLKRDIASVSPETEVVSVEIELH
NPWDFEEVYACLHDFARGYEFQPEKEDYLIHITTGTHVAQICWFLLAEARYLPARLIQSSPPRKKEQPRGAGEVTIIDLD
LSLYNAIASRFAEERQQTLDFLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTGAGKSFLARRIFELKQARHQFSG
AFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREGLLRSANGGMLFLDEIGELGADEQAMLLKAIEEKTFYPFGSDRQV
SSDFQLIAGTVRDLRQLVADGKFREDLYARINLWTFTLPGLRQRQEDIEPNLDYEVERHASLTGDSVRFNTEARRAWLAF
ATSPQATWRGNFRELSASVTRMATFASSGRITLDVVEDEINRLRYNWQESRPSALTALLGAEAENIDLFDRMQLEHVIAI
CRQAKSLSAAGRQLFDVSRQGKASVNDADRLRKYLARFGLTWEAVQDQHSSS
>SEQF1516_EDU87995.1 mannitol-1-phosphate 5-dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVDAVSSIGDDVVDLIAQV
DLVTTAVGPVVLERIAPAIAKGLVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRI
VPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNTGHAITAYLGKLAGHQTIRDAIL
DEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQKILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYSLP
HKNLIQGIAGAMHFRSEDDPQAQELAALIADKGPQAALAQISDLDANSEVVSEAVTAYKAMQ
>SEQF1516_EDU87996.1 multidrug resistance protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRHRNINLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGAVQSVMGAYLLTYGVSQLFYGPISDRVGRRPVILVGM
SIFMLATLVAVTTSSLTVLIAASAMQGMGTGVGGVMARTLPRDLYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWN
WRACYLFLLVLCAGVTFSMARWMPETRPVDAPRTRLLTSYKTLFGNSGFNCYLLMLIGGLAGIAAFEACSGVLMGAVLGL
SSMTVSILFILPIPAAFFGAWFAGRPNKRFSTLMWQSVICCLLAGLLMWIPDWFGVMNVWTLLVPAALFFFGAGMLFPLA
TSGAMEPFPFLAGTAGALVGGLQNIGSGVLASLSAMLPQTGQGSLGLLMTLMGLLIVLCWLPLATRMSHQGQPV
>SEQF1516_EDU87997.1 rhodanese domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQEIMQFVGRHPILSIAWIALLVAVLVTTFKSLTSKVKVITRGEATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSE
IKANNVGELEKHKDKPVIVVDGSGMQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK
>SEQF1516_EDU87998.1 auxiliary transport protein, membrane fusion protein (MFP) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLLIILTYVAFAWAMFKIFKIPVNKWTIPTAALGGIFIVSGLILLMNYNHPYTFKAQKAVISIPVVPQVTGVVIEVTDK
KNTLIKKGEVLFRLDPTRYQARVDRLMADIVTAEHKQRALGAELDEMAANTQKAKATRDKFAKEYQRYARGSQAKVNPFS
ERDIDVARQNYLAQEASVKSSAAEQKQIQSQLDSLVLGEHSQIASLKAQLAEAKYNLEQTIVRAPSDGYVTQVLIRPGTY
AASLPLRPVMVFIPDQKRQIVAQFRQNSLLRLAPGDDAEVVFNALPGKVFSGKLAAISPAVPGGAYQSTGTLQTLNTAPG
SDGVIATIELNEHTDLSALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWVHYLYLDH
>SEQF1516_EDU87999.1 acyl carrier protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQALYLEIKNLIISTLNLDELTPDDIDTDAPLFGDGLGLDSIDALELGLAVKNEYGIVLSAESEEMRQHFFSVATLASFI
AAQRA
>SEQF1516_EDU88000.1 tRNA modification GTPase TrmE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKLPKPRYADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLE
LQGHGGPVILDLLLKRILTIPGLRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLV
EALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMKVVIAGRPNAGKSSLLNALAGRE
AAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLREASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEF
IARLPAKLPITVVRNKADITGETLGMSEVNGHALIRLSAKTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRHLQALEQAA
EHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSFCIGK
>SEQF1516_EDU88001.1 hns-dependent expression protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLAVDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVT
PAIVQACTQDKQANFKDKVKGEWDKIKKDM
>SEQF1516_EDU88002.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTGSQVIDAEEDRHKLVVEYKDALQPADFYHNFKQRGIRSVQLIPHLEFDDRGDMTAASVTAELWGKFLIALFECWVRAD
ISRISIELFDATLQKWCGSENPQPRRGCQACDWHLLCPHAREETPDSVLCAGYQAFYSYSAPHMRVMRDLIKQHRSPMEL
MTMLR
>SEQF1516_EDU88003.1 conserved integral membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNANVLPPSKRPALLWGLVCLVMAVALLILLPQSRLNSSVLAMLPKQTMGDIPPALNDGFMQRLDRQLVWLVSPGKEAN
PLVAQEWLTLLQKSAALGDVKGPMDAASQQAWGAFFWQHRNGLIDPNTRARLQNGGEAQAQWILSQLYSAFSGVSGKELQ
NDPLMLMRGSQLAMAKNGQRLRLMDGWLVTQDPQGNYWYLLHGELAGSSFDMQQTHQLITTLNTLEKDLKTRYPQAQLLS
RGTVFYSDYASQQAKQDISTLGVATLLGVILLIVAVFRSLRPLLLCVISIGIGALAGTVATLLIFGELHLMTLVMSMSVI
GISADYTLYYLTERMVHGNDVSPWQSLAKVRNALLLALLTTVAAYLIMMLAPFPGIRQMAIFAAVGLSASCLTVLFWHPW
LCRGLPVRPVPAMALMLRWLAAWRRNKKLSLGLPVALALFSLAGMSMLRVDDDISQLQALPQHILAQEKAITALTGQSVD
QKWFVVYGDSPQQTLRRLEKYTASLEYAKKEGLISNYRTIPLNSLARQEEDLQLLKTAAPTVTKALQNAGLTAVNPDLNA
MPVNVDEWLASPASEGWRLLWLTLENGESGVLVPVEGVKSSALMQEIATYYPCGIAWVDRKSTFDELFALYRYVLTGLLL
VALAVIACGAVARLGWRKGLISLVPSVLSLGCGLAVLAMSGQAVNLFSLLALVLVLGIGINYTLFFSNPRGTPLTSLLAI
ALAMLTTLLTLGMLVFSATQAISSFGIVLVSGIFTAFLLSPLAMPDKKRTKK
>SEQF1516_EDU88004.1 SIS family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHTIVEEMVKRDIDRIYFVACGSPLNAAQTAKHLADRFSDLQVYAISGW
EFCDNTPYRLDARCAVIGVSDYGKTEEVIKALELGRACGALTAAFTKRADSPITSAAEFSIDYQADCIWEIHLLLCYSVV
LEMITRLAPHAEIGKIKNDLKQLPNALGYLVRTWEEKGRQLGELASQWPMIYTVAAGPLRPLGYKEGIVTLMEFTWTHGC
VIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTERAINFVKQRTDNVIVIDYAAISQGLHPWLAPFLMFVPMEWLCYYL
SIYKDHNPDERRYYGGLVEY
>SEQF1516_EDU88005.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNGKLQTSDVKNETPYNIPLLINENVISSGISLISLWHTYADEHYRVIWPRDKKKPLIANSWVAVYTVQGCGKILLKNGE
QITLHGNCIIFLKPMDIHSYHCEGLVWEQYWMEFTPTSMMDIPIGQQSVIYNGEIYNQELTEVAELITSPEAIKNNLAVA
FLTKIIYQWICLMYADGKKDPQRRQIEKLIATLHASLQQRWSVADMAATIPCSEAWLRRLFLRYTGKTPKEYYLDARLDL
ALSLLKQQGNSVGEVADTLNFFDSFHFSKAFKHKFGYAPSAVLKNTDQHPTDASPHN
>SEQF1516_EDU88006.1 phosphate ABC transporter, permease protein PstA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMVEMQTTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFWLIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGLA
NALAGSGLLILWATVFGTPLGIMAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL
ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWST
DMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIITLCVLLLNILARVVFAKNKHG
>SEQF1516_EDU88007.1 ST25 protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKINSQIKEVDGKLDDCEQSIKESIASKQAYCASLVNLDKVSLYKYQIKNNAFDEQKQRLYEKKSSLSKEKRSLLDSQK
RTKENLQHVNKSVEKLSFAIKEHYFD
>SEQF1516_EDU88008.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIYCNKDDSQEASSQTPFLPLGFAFTTLYICQPDYSGGEDESMDGDINKYLVLAIICVGGLSGLVASQSTGRNFPPATAN
KTVGR
>SEQF1516_EDU88009.1 glycogen debranching enzyme GlgX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQEHRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQP
AEGHRFNPAKLLIDPCARQIDGEFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKG
LTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNYWGYNPVAMFALHPAYACSPETA
LHEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPLFSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASAC
LRYWVETCHVDGFRFDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEWNDHFRDAA
RRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDCVCFNHKHNEANGEENRDGTNNNYSNNHGKE
GVGGTLDLVERRRDSIHALLTTLLLSQGTPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKR
IPALVENRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPAGEWHAIPPFAGEDNPV
ITAVWQGPAHGLCVFQR
>SEQF1516_EDU88010.1 hypothetical protein ECH7EC4501_0731 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHSHSIVWRTRVIDKAIIVLGALIALLELIRFLLQLLN
>SEQF1516_EDU88011.1 pyridine nucleotide-disulfide oxidoreductase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MERFDAIIIGAGAAGMFCSALAGQAGRRVLLIDNGKKPGRKILMSGGGRCNFTNLYVEPGAYLSQNPHFCKSALARFTQW
DFIDLVNKHGIAWHEKTLGQLFCDDSAQQIVDMLVDECEKGNVTVRLRSEVLSVAKDDTGFTLELNGMTVGCEKLVIATG
GLSMPGLGASPFGYKIAEQFGLNVLPTRAGLVPFTLHKPLLEELQVLAGVAVPSVITAENGTVFRENLLFTHRGLSGPAV
LQISSYWQPGEFVSINLLPDVDLETFLNEQRNAHPNQSLKNTLAVHLPKRLVERLQQLGQIPDVSLKQLNVRDQQALIST
LTDWRVQPNGTEGYRTAEVTLGGVDTNELSSRTMEARKVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQDLIAAKSC
>SEQF1516_EDU88012.1 glutathione-regulated potassium-efflux system ancillary protein kefG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLK
EWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSA
QELASHARAYGDWLANPLSPGGR
>SEQF1516_EDU88013.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQAPMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAI
GAFFLSHLLYTIYFASQMTLSFFWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALS
AFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL
>SEQF1516_EDU88014.1 cyclic di-GMP binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRKLFWICAVAMGMSAFPSFMTQATPATQPLINAEPAVAAQTEQNPQVGQVMPGVQGADAPVVAQNGPSRDVKLTFAQI
APPPGSMVLRGINPNGSIEFGMRSDEVVTKAMLNLEYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQMPIN
PLFITDFNRVRLEFVGHYQDVCENPASTTLWLDVGRSSGLDLTYQTLNVKNDLSHFPVPFFDPRDNRTNTLPMVFAGAPD
VGLQQASAIVASWFGSRSGWRGQNFPVLYNQLPDRNAIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNPYVKLLVVFGR
DDKDLLQAAKGIAQGNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAAINVSLNLPP
DLYLMRSTGIDMDINYRYTMPPVKDSSRMDISLNNQFLQSFNLSSKQEANRLLLRIPVLQGLLDGKTDVSIPALKLGATN
QLRFDFEYMNPMPGGSVDNCITFQPVQNHVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQTITVMPKTPN
EAQMETLLNTVGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIIGGIPDKLKDDKQIDLLVQATESWVKTPMRQTPFPGI
VPDESDRAAETQSTLTSSGAMAAVIGFQSPYNDQRSVIALLADSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLR
VGDVYYVGHLPWFERLWYALANHPILLAVLAVLAVLAAISVILLAWVLWRLLRIISRRRLNPDNE
>SEQF1516_EDU88015.1 formamidopyrimidine-DNA glycosylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRLSDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRI
LPEELPPEKHDHVDLVMSNGKVLRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMD
NKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLKDFLQSDGKPGYFAQELQVYGRK
GEPCRVCGTPIVATKHAQRATFYCRQCQK
>SEQF1516_EDU88016.1 2-ketogluconate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFAEAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNF
DVDALTARKILLMHTPTVLTETVADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMAL
AQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLFGAEQFAKMKSSAIFINAGRGPV
VDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLSMANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNP
HVAD
>SEQF1516_EDU88017.1 phosphoglycolate phosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKFEDIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEERVITWIGNGADVLMERALTWARQERATLRKTMGKPP
VDDDIPAEEQVRILRKLFDRYYGEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGG
DDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGEAIDLSQPDVIYQSINDLLPALG
LPHSENQESKND
>SEQF1516_EDU88018.1 glutamate decarboxylase GadA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDQKLLTDFRSELLDSRFGAKAISTIAESKRFPLHEMRDDVAFQIINDELYLDGNARQNLATFCQTWDDENVHKLMDLSI
NKNWIDKEEYPQSAAIDLRCVNMVADLWHAPAPKNGQAVGTNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCG
PVQICWHKFARYWDVELREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADTGIDIDM
HIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHKFGLAPLGCGWVIWRDEEALPQELVFNVDYLGGQIGTFAINFSRP
AGQVIAQYYEFLRLGREGYTKVQNASYQVAAYLADEIAKLGPYEFICTGRPDEGIPAVCFKLKEGEDPGYTLYDLSERLR
LRGWQVPAFTLGGEATDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSDHPKLQGIAQQNSFKHT
>SEQF1516_EDU88019.1 DNA repair protein RadC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTLAKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQL
KGIAELARRYYNVRMREESPLLSPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAI
KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAERGWI
>SEQF1516_EDU88020.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTSKTVAKLLFVVGALVYLVGLWISCPLLSGKGYFLGVLMTATFGNYAYLRAEKLGQLDNFFTHICQLVALITIGLLFI
GVLNAPINAYEMVIYPIAFFVCLFGQMRLFRSV
>SEQF1516_EDU88021.1 phospholipid/glycerol acyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKLMSRLEWTWRLVMTGLCFALFGLGGLLLSVVWFNILLVLVWDTSRRRRLARRSIAASFRLFLTVAKGLGVLDYRIDG
AEILHQERGCLVVANHPTLIDYVLLASVMPETDCLVKSALLKNPFLGGVVRATDYLINSEAETLLPRCQQRLAQGDTILI
FPEGTRTKPGEKMTLQRGAANIAVRCASDLRIVTIGCSEHLLDKQSKWYDVPPDRPFFTVAVHGRVEINKFYDATSQEPA
LAARQLNRHLLLQLQQGCLPLSGINNASALSGN
>SEQF1516_EDU88022.1 chaperonin HslO [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNVLAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVI
NGNNNQQMRGVARVQGEIPENADLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGD
VDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEVTVYDPQDVEFKCTCSRERCADA
LKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMDIAEIRNNASPADPQVH
>SEQF1516_EDU88023.1 SepD protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNNNGIAKNDCDWLTALDFVKDVNGSPTHLTFYIYQKNAFLHDFGNYWVLYIELSGDFRQVPTDTFIRLCNILAVSNEY
KQMGIFLSNKKWYLCQIFHKDNNHRANMSKAIMQHTLASLLDKQFDKLEQLSSSDTMMPPTHLFSDIGRIV
>SEQF1516_EDU88024.1 IpaB/EvcA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNGAQSSIGHFLQSNKYFNQKVDEQCGKRVDPITRFNTQTKMIEQVSQEIFERNFSGFKVSEIKAITQNAILEHVQDTRL
>SEQF1516_EDU88025.1 cellulose biosynthesis protein BcsF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMTISDIIEIIVVCALIFFPLGYLARHSLRRIRDTLRLFFAKPRYVKPAGTLRRTEKARATKK
>SEQF1516_EDU88026.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVALALARVPGYVPSFPPVWDITLEHPPSNAIPLHIMNANNTFLIIINSSVDRGCWPDEL
>SEQF1516_EDU88027.1 DNA gyrase, B subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVVDNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPT
GIHPEEGVSAAEVIMTVLHAGGKFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGET
EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHYEGGIKAFVEYLNKNKTPIHPNI
FYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQRDGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLI
AVVSVKVPDPKFSSQTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMTRRKGALDL
AGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKILNVEKARFDKMLSSQEVATLITALGCGIGR
DEYNPDKLRYHSIIIMTDADVDGSHIRTLLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIA
LDGATLHTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQTVTRWVNALVSELNDK
EQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFITGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFE
QALDWLVKESRRGLSIQRYKGLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALKAA
NIDI
>SEQF1516_EDU88028.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPHEIERHQAQTNHLEIVLHLRADLFWFRGHFAVQPLLPGVAQIDWAMSYALNLLAPGWRFHSIQNIKFQSPLLPENRV
TLALNWQEERQILSFSYQRHDGDARHTASSGKIRLCR
>SEQF1516_EDU88029.1 di-haem cytochrome c peroxidase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKMVSRITAIGLAGVAICYLGLSGYVWYHDNKRSKQADVQASAVSENNKVLGFLREKGCDYCHTPSAELPAYYYIPGAKQ
LMDYDIKLGYKSFNLEAVRAALLADKPVSQSDLNKIEWVMQYETMPPTRYTALHWAGKVSDEERAEILAWIAKQRAEYYA
SNDTAPEHRNEPVQPIPQKLPTDAQKVALGFALYHDPRLSADSTISCAHCHALNAGGVDGRKTSIGVGGAVGPINAPTVF
NSVFNVEQFWDGRAATLQDQAGGPPLNPIEMASKSWDEIIAKLEKDPQLKAQFLDVYPQGFSGENITDAIAEFEKTLITP
DSPFDKWLRGDENALTAQQKKGYQLFKDNKCATCHGGIILGGRSFEPLGLKKDFNFGEITAADIGRMNVTKEERDKLRQK
VPGLRNVALTAPYFHRGDVPTLDGAVKLMLRYQVGKELPQEDVDDIVAFLHSLNGVYTPYMQDKQ
>SEQF1516_EDU88030.1 cell division ATP-binding protein FtsE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIRFEHVSKAYLGGRQALQGVTFHMQPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQ
IGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL
ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDINLISRRSYRMLTLSDGHLHGGVGHE
>SEQF1516_EDU88031.1 arsenate reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSNITIYHNPACGTSRNTLEMIRNSGTEPTIIHYLETPPTRDELVKLIADMGISVRALLRKNVEPYEELGLAEDKFTDDR
LIDFMLQHPILINRPIVVTTLGTRLCRPSEVVLEILPDAQKGAFTKEDGEKVVDEAGKRLK
>SEQF1516_EDU88032.1 secreted protein EspB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTIDNTQVTMVNSASESTTGASSAVAASALSIDSSLLTDGKVDICKLMLEIQKLLGKMVTLLQDYQQKQLAQSYQIQQA
VFESQNKAIEEKKAAATAALVGGIISSALGILGSFAAMNNAAKGAGEIAEKASSASSKAAGAASEVANKALVKATESVAD
VAEEASSAMQKAMATTTKAASRASGVADDVAKASDFAEDLADAAEKTSRINKLLNSVDKLTNTTAFVAVTSLAEGTKTLP
TTISESVKSTHEVNEQRAKSLENFQQGNLELYKQDVRRTQDDITTRLRDITSAVRDLLEVQNRMGQSGRLAG
>SEQF1516_EDU88033.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQFTQNTAMPSSLWQYWRGLSGWNFYFLVKFGLLWAGYLNFHPLLNLVFAAFLLMPIPRYSLHRLRHWIALPIGFALFW
HDTWLPGPESIMSQGSQVAGFSTDYLIDLVTRFINWQMIGAIFVLLVAWLFLSQWIRITVFVVAILLWLNVLTLAGPSFS
LWPAGQPTTTVTTTGGNAAATVAATGGAPVVGDMPAQTAPPTTANLNAWLNNFYNAEAKRKSTFPSSLPADAQPFELLVI
NICSLSWSDIEAAGLMSHPLWSHFDIEFKNFNSATSYSGPAAIRLLRASCGQTSHTNLYQPANNDCYLFDNLSKLGFTQH
LMMGHNGQFGGFLKEVRENGGMQTELMDQTNLPVILLGFDGSPVYDDTAVLNRWLDVTEKDKNSRSATFYNTLPLHDGNH
YPGVSKTADYKARAQKFFDELDAFFTELEKSGRKVMVVVVPEHGGALKGDRMQVSGLRDIPSPSITDVPVGVKFFGMKAP
HQGAPIVIDQPSSFLAISDLVVRVLDGKIFTEDNVDWKKLTSGLPQTAPVSENSNAVVIQYQDKPYVRLNGGDWVPYPQ
>SEQF1516_EDU88034.1 siroheme synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALAFIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAAT
DDDALNQRVSEAAEARRIFCNVVDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQ
LRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEVVLVGAGPGDAGLLTLKGLQQIQ
QADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHCVPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNA
GIPFSVVPGITAASGCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQKLIEHGMP
GEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDKLNWFSNH
>SEQF1516_EDU88035.1 ADP-glyceromanno-heptose 6-epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVDLNIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSS
TTEWDGKYMMDNNYQYSKELLHYCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANS
QIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVADVNLWFLENGVSGIFNLGTGRA
ESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFTQADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA
>SEQF1516_EDU88036.1 lipopolysaccharide core biosynthesis protein RfaG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVAFCLYKYFPFGGLQRDFMRIAQTVAARGHHVRVYTQSWEGECPDVFELIKVPVKSHTNHGRNAEYFAWVQKHLREHP
VDKVVGFNKMPGLDVYYAADVCYAEKVAQEKGFFYHLTSRYRHYAAFERATFEQGKPTQLLMLTDKQIADFQKHYQTEAE
RFHILPPGIYPDRKYSQQPANSREIFRKKNGITEQQYLLLQVGSDFTRKGVDRSIEALASLPDSLRHNTLLYVVGQDKPR
KFEALAEKRGVRSNVHFFSGRNDVSELMAAADLLLHPAYQEAAGIVLLEAITAGLPVLTTAVCGYAHYIVDANCGEAIAE
PFRQETLNEILRKALTQSSLRQAWAENARHYADTQDLYSLPEKAADIITGGLDG
>SEQF1516_EDU88037.1 Fic family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIKSPPTLIPLSHLSGEELQAHLRFNRVTDEKGRYLPFDELQYRIKKGENVDVAWTLTRLARNAAIQRINYCNEAGEQA
GFNITPVIAEACELVDKRATALALKDQTERLRGAGAELSQLRLEEPITSSQLEGANTTTLVARKMLETGRSPRTEDEHMI
AGNARLMAEIPHLLAEPLTPALIRQLHAIGMGGINDAKYRPGEFRETDDVVIADYDGNIVHQPPAAALLPERLEKVCQWL
NSHEGYIHPLVRACILHFMLAHEHPFRDGNGRTSRALFYWYMLKSGYDVFKYISISRLLHAAPVKYAASYQYTESDGMDL
TYFLEYQAGVIKRALQNWQQHIDEITQRSAKLDSVLFSSGVLKRLNPRQVTLLNVMLANPGKEYTVAEISASLGVSDNTV
RADLRTIVKEGFAQEKKINDQQAVYFAHYPL
>SEQF1516_EDU88038.1 lipoprotein NlpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLTTHHLRAGAALLLAGVLLAGCDQSSSDEKHIKVGVINGAEQDVAEVAKKVAKEKYGLDVELVGFSGSLLPNDATNNG
ELDANVFQHRPFLEQDNQTHGYKLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITLKE
GKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDPKVDVAIISTTYIEQTGLSPVNDSVFIEDKNSPYVNILVAREDNKN
AENVKEFLQSYQSPEVAKAAETIFNGGAVPGW
>SEQF1516_EDU88039.1 secreted protein EspA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSYMYQAQSNLSIAKFADMNEASKASTTAQKMANLVDAKIADVQSSTDKNAKAKLPQDVIDYINDPRNDISVTGIRDLS
GDLSAGDLQTVKAAISAKANNLTTVVNNSQLEIQQMSNTLNLLTSARSDVQSLQYRTISAISLGK
>SEQF1516_EDU88040.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDSRKARRIADPGLQPERTSLAWFRTMLGYGALMALAIKHNWHQAGMLFWISIGILAIVALILWHYTRNRNLMDVTNSD
FSQFHVVRDKFLISLAVLSLAILFAVTHIHQLIVFIERVA
>SEQF1516_EDU88041.1 multidrug resistance protein MdtL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFII
TSVFCSLAETSTLFLAGRFLQGLGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLF
WTMAIMGIAVLMLSLFILKETRPAAPAASDKSRENSESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGFERGEY
ATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQVLFLAAGITLTVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPF
SLRAGVASSTLGIAQVCGSSLWIWLAAVVGISAWNMLIGILIACSIVSLLLIMFVAPGRPVTAHEEIHHHA
>SEQF1516_EDU88042.1 hypothetical protein ECH7EC4501_0925 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSISRSQCAGQKNITKSGAGTQNRIEVAGKKNAALFEWAAFVKAEK
>SEQF1516_EDU88043.1 adenine deaminase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYTDAPALQRIDAHGA
TAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYIAAGIENCHESYQL
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVAS
WSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESAKLAQSAPPYGNTIARQPVSASDFAL
QFTPGKRYRVIDVIHNELITHSHSSVYSENGFERNDVCFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSL
PVIPALKLTSQGLFDGEKFAFTTLEVTE
>SEQF1516_EDU88044.1 inner membrane protein OxaA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVE
QALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
FTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIAD
NENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAV
APHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDD
KQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQK
MSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS
>SEQF1516_EDU88045.1 hypothetical protein ECH7EC4501_0976 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRFVPFSGLITPVFSSTELFPLSEVASGITAPEGLKFAASIDLSPFV
>SEQF1516_EDU88046.1 dipeptide ABC transporter, ATP-binding protein DppF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTQEATSQQPLLQAIDLKKHYPVKKGMFAPERLVKALDGVSFNLERGKTLAVVGESGCGKSTLGRLLTMIETPTGGELY
YQGQDLLKHDPQAQKLRRQKIQIVFQNPYGSLNPRKKIGQILEEPLLINTSLSKEQRREKALSMMAKVGLKTEHYDRYPH
MFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRC
VEKGTKDQIFNNPRHPYTQALLSATPRLNPDDRRERIKLTGELPSPLNPPPGCAFNARCRRRFGPCTQLQPQLKDYGGQL
VACFAVDQDENPQR
>SEQF1516_EDU88047.1 D-xylose ABC transporter, periplasmic D-xylose-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKNILLTLCTSLLLTNVAAHAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINR
GVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNN
AKLFRAGQMKVLQPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVA
ISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTSLNNGLKDVPSRLLTPIDVNKNNIKDTVI
KDGFHKESEL
>SEQF1516_EDU88048.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSFPSEWCILLTEPFESTNAIKKTGIISLYLLFIAIALYGFIQLKRDCFQRLWIIPGR
>SEQF1516_EDU88049.1 nickel ABC transporter, ATP-binding protein NikD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPQQIELRNIALQAAQPLVHGVSLTLKRGRVLALVGGSGSGKSLTCAATLGILPAGVRQTAGEILADGKPVSPCALRGIK
IATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESP
FIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSDGKIVEQGDVETLFNAPKHAVTRSL
VSAHLALYGMELAS
>SEQF1516_EDU88050.1 AsmA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFIGKLLLYILIALLVVIAGLYFLLQTRWGAEHISAWVSENSDYHLAFGAMDHRFSAPSHIVLENVTFGRDGQPATLVA
KSVDIALSSRQLTEPRHVDTILLENGTLNLTDQTAPLPFKADRLQLRDMAFNSPNSEWKLSAQRVNGGVVPWSPEAGKVL
GTKAQIQFSAGSLSLNDVPATNVLIEGSIDNDRVTLTNLGADIARGTLTGNAQRNADGSWQVENLRMADIRLQSEKSLTD
FFAPLRSVPSLQIGRLEVIDARLQGPDWAVTDLDLSLRNMTFSKDDWQTQEGKLSMNASEFIYGSLHLFDPIINAEFSPQ
GVALRQFTSRWEGGMVRTSGNWLRDGKTLILDDAAIAGLEYTLPKNWQQLWMETTPGWLNSLQLKRFSASRNLIIDIDPD
FPWQLTTLDGYGANLTLVTDHKWGVWSGSANLNAAAATFNRVDVRRPSLALTANSSTVNISELSAFTEKGILEATASVSQ
TPQRQTHISLNGRGVPVNILQQWGWPELPLTGDGNIQLTASGDIQANVPLKPTVSGQLHAVNAAKQQVTQTMNAGVVSSS
EVTSTEPVQ
>SEQF1516_EDU88051.1 PilN family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNPPINFLPWRQQRRTAFLRFWLLMFVAPLLLAVGITLILRLTSSAEARVDAVLLQGEQQLARSLQITKPRLLERQQIRE
QRLQRQRQRQFTRDWQSALEALAALLPEHAWLTTISWQQGTLEIKGLTTSITALNALETSLRQDASFHLNQRGATQQDAQ
GRWQFEYQLTRKVSDEHVL
>SEQF1516_EDU88052.1 type III secretion apparatus protein, YscR/HrcR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQLMTIGSQPIFLIIVFFLLSLLPIFVVIGTSFLKISIVLGILKNALGIQQVPPNMALTSVSLILTMFIMSPIILQIND
NISQEPINYTDSDFFQKVDEKILSPYRGFLEKNTEKDNVEFFERAAQKKLGNETILKKDSLFILLPAFTMGQLEAAFKIG
FLLYLPFIAIDLIISNILLALGMMMVSPVTISIPFKILLFILVGGWQKLFEFLLVVN
>SEQF1516_EDU88053.1 hypothetical protein ECH7EC4501_0919 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQGGKATGKSAHFSQKRNATGSAKRNRYAMIEKARKFTGFG
>SEQF1516_EDU88054.1 L-threonine 3-dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHIYNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFK
IGDRVSGEGHITCGHCRNCRGGRTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSF
DLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKENLNDVMAELGMTEGFDVGLEMS
GAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKVIFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDD
FQKGFDAMCSGQSGKVILSWD
>SEQF1516_EDU88055.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKRQLQCGEAVLVWSELHETVNIMPRSQFRE
>SEQF1516_EDU88056.1 DNA-directed RNA polymerase, omega subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEENDKTTVIALREIEEGLINNQILDVRERQEQQEQEAAEL
QAVTAIAEGRR
>SEQF1516_EDU88057.1 glycerol-3-phosphate-binding periplasmic protein precursor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPLHYTASALALGLALMGNAQAVTTIPFWHSMEGELGKEVDSLAQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGN
APAILQVYEVGTATMMASKAIKPVYDVFKEAGIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGL
DPEQPPKTWQDLADYAAKLKASGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDGTDAVLEFNKPEQVKHIAMLEEM
NKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKDKET
YTGVAKFLDFLAKPENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADTATRQMLNKPPLPFTKGLRLGNMPQIRVIV
DEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS
>SEQF1516_EDU88058.1 hypothetical protein ECH7EC4501_0562 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLLLVMIGLRSKIKWHSGICRERAILGDFVICLNVLLQSVAKLHFKR
>SEQF1516_EDU88059.1 chaperone protein FimC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKSKFVALALSLFLSQSVLAGGVGLSSTRVIYDGSKKEASLTVQNKSKTEEFLIQSWVDDAAGSKKTPFIITPPLFKLD
PEKNNILRIVNITPGLPQDRESVYWVNVKAIPSKSDDSENKNVLQIAVRTRIKLFYRPAGLKGDVKTAPNELRFTRNGNQ
LRVDNPTVFNITFNQFFANDKEIEKAGMVPAKGALNITLPAGVGSVSKIKYNTINDFGSSAEMITKNVD
>SEQF1516_EDU88060.1 pirin family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVINDDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSMG
NKEQVPAGEFQIMSAGTGIRHSEYNPSSTERLHLYQIWIMPEENGITPRYEQRRFDAVQGKQLVLSPDARDGSLKVHQDM
ELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGVKASISDGLAIWDEQAISIHADSDSEVLLFDLPPV
>SEQF1516_EDU88061.1 PTS system, mannitol-specific IIABC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLPNETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVV
GAITTMGVIVGADMPMFLGSMIAGPLGGWCIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPIVETLSKM
LAAGVNFMVVHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIEANPGPGMGVLLAYMFFGRGSAK
QSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILGGMTGVFTLTILGGGLVSPASPGSILAVLAMTPKGAYFANIAGVC
AAMAVSFVVSAILLKTSKVKEEDDIEAATRRMQDMKAESKGASPLSAGDVTNDLSHVRKIIVACDAGMGSSAMGAGVLRK
KIQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLTNFLDSGLYTSLTERLVAAQRHTENEVKVKD
SLKDSFDDSSANLFKLGAENIFLGRKAATKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAK
DRVLKTGVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTTSVDEVLELLAGRK
>SEQF1516_EDU88062.1 acyl carrier protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTEQQTVYQEVSALLVKLFEIDPQDIKPETRLYEDLELDSIDAVDMIVHLQKKTGKKIKPEEFKAVRTVQDVVEAVERLL
QEA
>SEQF1516_EDU88063.1 serine transporter family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQHNTLPKHDQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGLKGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCND
YTDIISHYLGKNWGIFLGVIYFLMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLLYKVAIFAVLVAIASGGERLLF
KISGPMVVVKVGIIVVFGFTMIPHWNFANITAFPQASVFFRDVLLTIPFCFFSAVFIQVLNPMNIAYRKREADKVLATRL
ALRTHRISYITLIAVILFFAFSFTFSISHEEAVSAFEQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHE
AIKGIILNLLSRIIDTKKINSRVLTLAICAFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKVAQLEKLRG
FKTWLILLYGILLCLSPLLKLIE
>SEQF1516_EDU88064.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDIKVPENISGIFIPQPNSQYISLIFITSLTTETLIKH
>SEQF1516_EDU88065.1 putative HdeD protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYIDKATILKFDLEMLKKHRRAIQFIAVLLFIVGLLCISFPFVSGDILSTVVGALLICSGIALIVGLFSNRSHNFWPVL
SGFLVAVAYLLIGYFFIRAPELGIFAIAAFIAGLFCVAGVIRLMSWYRQRSMKGSWLQLVIGVLDIVIAWIFLGATPMVS
VTLVSTLVGIELIFSAASLFSFASLFVKQQ
>SEQF1516_EDU88066.1 nickel ABC transporter, permease protein NikC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNFFLSSRWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSRLLSPDAQHWLGTDHLGRDIFSRLMAATRVSLGSVMA
CLLLVLTLGLVIGGSAGLIGGRVDQATMRVADMFMTFPTSILSFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISL
RQREFVLASRLSGAGHVRVFVDHLAGAVIPSLLVLATLDIGHMMLHVAGMSFLGLGVTAPTAEWGVMINDARQYIWTQPL
QMFWPGLALFISVMAFNLVGDALRDHLDPHLVTEHAH
>SEQF1516_EDU88067.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLHILYLVGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGGSVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAP
VMPYLRKVFLVLDALGLVVFSIIGAQVALDMGHGPIIAVVAAVTTGVFGGVLRDMFCKRIPLVFQKELYAGVSFASAVLY
IALQHYVSNHDVVIISTLVFGFFARLLALRLKLGLPVFYYSHEGH
>SEQF1516_EDU88068.1 hypothetical protein ECH7EC4501_0907 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQCLTDSIAIFTVTAATEREARARLPHAHLIFVARIRQEVTHA
>SEQF1516_EDU88069.1 ATP synthase F1, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPV
GKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
FVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATV
VLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRF
LSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIEEAVEKAKKL
>SEQF1516_EDU88070.1 ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLLALLKNEISADGGSYTFPGSWQLAWVNQETPALPQAA
LEYVIDGDREYRQLEAQLHDANERNDGHAIATIHGKLDAIDAWSIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNL
AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKIIHIEQQSMFEYTGNYSSFEVQRAT
RLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQAQSRIKMLERMELIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSA
GYGDRIILDSIKLNLVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEYLRADESPIQHLAR
LAPQELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIEFEGAL
VVVSHDRHLLRSTTDDLYLVHDRKVEPFDGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPL
RKEIARLEKEMEKLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQEQLEQMLLEGQSN
>SEQF1516_EDU88071.1 Q protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRDIQQVLERWGAWAANNRENVTWSSVAAGFKGIIPAKITSRSQCCDDDAMVICGCIARLYRNNRDLHDLLVDYYVLGET
FMALARKHGCSDTCIGKRLHKAEGVVEGMLMMLDVKLEMDRYVERDSVTA
>SEQF1516_EDU88072.1 hypothetical protein ECH7EC4501_0993 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRKPLIAFFIAIFIALTILILFPFNCTYKKSPQEHSLSFIKQLPNTVNLSSLTYNKEDDFLYATQNSPAQLLKITKSGD
IMDRAPLPFISDAETIEHIQGNIFAAVDEKTSELFFFTVTKDMHISFRNKIQLEKFNKKNRGFEGLAWKADDRMLFVAKE
RRPSKIFIYQLSPDLLSVKQATIPEALNDIRVNDISGLAFNNESLMILSDESRKLLKFNLTEMSFIEMLDLTKGNHSLTS
DLPQPEGIVTLPDESIYVASEPDILAKFVPNK
>SEQF1516_EDU88073.1 glucose-1-phosphate adenylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPAVHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTL
VQHIQRGWSFFNEEMNEFVDLLPAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKG
ARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVFDADYLYELLEEDDRDENSSHDF
GKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRDVGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQ
DRSGSHGMTLNSLVSGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPEGMVIGENA
EEDARRFYRSEEGIVLVTREMLRKLGHKQER
>SEQF1516_EDU88074.1 ribosomal protein L28 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEKRFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY
>SEQF1516_EDU88075.1 glycerol-3-phosphate regulon repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELAEQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKER
IARKVAEQIPNGSTLFIDIGTTPEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
SQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVNMGSISMVDAVYTDTPPPVSVMQ
VLTDHHIQLELC
>SEQF1516_EDU88076.1 sodium/glutamate symporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFHLDTLATLVAATLTLLLGRKLVHSVSFLKKYTIPEPVAGGLLVALALLVLKKSMGWEVNFDMSLRDPLMLAFFATIGL
NANIASLRAGGRVVGIFLIVVVGLLVMQNAIGIGMASLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFIERYGFTNATEV
AMACATFGLVLGGLIGGPVARYLVKHSTTPNGIPDDQEVPTAFEKPDVGRMITSLVLIETIALIAICLTVGKIVAQLLAG
TAFELPTFVCVLFVGVILSNGLSMMGFYRVFERAVSVLGNVSLSLFLAMALMGLKLWELASLALPMLAILVVQTIFMALY
AIFVTWRMMGKNYDAAVLAAGHCGFGLGATPTAIANMQAITERFGPSHMAFLVVPMVGAFFIDIVNALVIKLYLMLPIFA
G
>SEQF1516_EDU88077.1 phosphocarrier, HPr family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNKTVEVRNSTGLHARPAACLAKAAKKYSCKVTLHYEGNDINATSMMNIMRAGIKGGKTVEIRCDGDDENEAIQTLTDL
FRDRFGEAE
>SEQF1516_EDU88078.1 ribosomal protein L33 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVRQHVIYKEAKIK
>SEQF1516_EDU88079.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSSTTIITAYFDIGRGDWTANKGFREKLARSVDVYFSYFERLAALENEMIIFTSPDLKPRVEAIRNGKPTTVIVIDIKK
KFRYIRSRIEKIQKDESFTNRLEPRQLKNPEYWSPEYVLVCNLKAYFVNKAINMGLVKTPLVAWIDFGYCRKPNVTRGLK
IWDFPFDESKMHLFTIKKGLTVTSQQQVFDFMIGNHVYIIGGAIVGSQHKWKEFYKLVLESQKITLNNNIVDDDQGIFVM
CYYKRPDLFNLNYLGRGKWFDLFRCFRSNTLGAKMQALRIFLSRK
>SEQF1516_EDU88080.1 hypothetical protein ECH7EC4501_0913 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTFCKGVHQLFTLFTRDCSKIIQKGEQVNTLVNSFTKVFTH
>SEQF1516_EDU88081.1 OmpA family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKRVYLIAAVVSGALAVSGCTTNPYTGEREAGKSAIGAGLGSLVGAGIGALSSSKKDRGKGALIGAAAGAALGGGVGYY
MDVQEAKLRDKMRGTGVSVTRSGDNIILNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEYPKTAVNVIGYTDSTGGHDL
NMRLSQQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGKAQNRRVEITLSPL
>SEQF1516_EDU88082.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKISRLGEAPDYRFSLANERTFLAWIRTALGFLAAGVGLDQLAPDFATPVIRELLALLLCLFSGGLAMYGYLRWLRNEKA
MRLKEDLPYTNSLLIISLILMVVAVIVMGLVLYAG
>SEQF1516_EDU88083.1 MltA-interacting protein MipA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLINRNIVALFALPFMASATASELSIGAGAAYNESPYRGYNENTKAIPLISYEGDSFYVRQTTLGFILSQSEKNELSLTA
SWMPLEFDPADNDDYAMQQLDKRDSTAMAGVAWYHHERWGTVKASAAADVLDNSNGWVGELSVFHKMQIGRLSLTPALGV
LYYDENFSDYYYGISESESRRSGLASYSAQDAWVPYVSLTAKYPIGEHVVLMASAGYSELPEEITDSPMIDRNESFTFVT
GVSWRF
>SEQF1516_EDU88084.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPTMLLMITVFLIFPALSQAESPFSSLQSAKEKTTVLQDLRKICTPQASLSDEAWEKLMLSDENNKQHIREAIVAMERN
NQSNYWEALGKVECPDM
>SEQF1516_EDU88085.1 low affinity tryptophan permease TnaB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDQAEKKHSAFWGVMVIAGTVIGGGMFALPVDLAGAWFFWGAFILIIAWFSMLHSGLLLLEANLNYPVGSSFNTITKDL
IGNTWNIISGITVAFVLYILTYAYISANGAIISETISMNLGYHANPRIVGICTAIFVASVLWISSLAASRITSLFLGLKI
ISFVIVFGSFFFLVDYSILRDATSSTAGTSYFPYIFMALPVCLASFGFHGNIPSLIICYGKRKDKLIKSVVFGSLLALVI
YLFWLYCTMGNIPRESFKAIISSGGNVDSLVKSFLGTKQHGIIEFCLLVFSNLAVASSFFGVTLGLFDYLADLFKIDNSH
GGRFKTVLLTFLPPALLYLIFPNGFIYGIGGAGLCATIWAVIIPAVLAIKARKKFPNQMFTVWGGNLIPAIVILFGITVI
LCWFGNVFNVLPKFG
>SEQF1516_EDU88086.1 hypothetical protein ECH7EC4501_0660 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNTQHNPLNGSELFRPLCRYFMLTKALFSVYLSINSEYYLFLID
>SEQF1516_EDU88087.1 ribonuclease P protein component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDFVVVAKKGVANLDNRALSEALEKLWRRHCRLARGS
>SEQF1516_EDU88088.1 hypothetical protein ECH7EC4501_0732 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHPLTHPSPVTAHALLLDNGILTPARASVNGTTRTTEQDFESVYAHCQSENASELTG
>SEQF1516_EDU88089.1 high-affinity gluconate transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLDKVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGG
AQRIATTLIAKFGKKHIQWAVVLTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPGP
TAIATIFNADMGKTLLYGTILAIPTVILAGPVYARVLKGIDKPIPEGLYSAKTFSEEEMPSFGVSVWTSLVPVVLMAMRA
IAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFTFGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSG
VDKYIASMMHETNISPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSHVNDPGFWL
FKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI
>SEQF1516_EDU88090.1 hydrolase, alpha/beta fold family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAQITTTDANEFSSSAEFTPMRGFSNCHLQTMLPRLFRRKVKFTPYWQRLELPDGDFVDLAWSEAPAQAQHKPRLVVFHG
LEGSLNSPYAHGLVEAAQKRGWLGVVMHFRGCSGEPNRMHRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLA
CLLAKEGNDLPVDAAVIVSAPFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAYPGTLPINLAQLKSVRRIREFDD
LITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIHAKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQ
MWLESRIPDWLTTYLEAKSC
>SEQF1516_EDU88091.1 cellulose synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSILTRWLLIPPVNARLIGRYRDYRRHGASAFSATLGCFWMILAWIFIPLEHPRWQRIRAEHKNLYPHINASRPRPLDPV
RYLIQTCWLLIGASRKETPKPRRRAFSGLQNIRGRYHQWMNELPERVSHKTQHLDEKKELGHLSAGARRLILGIIVTFSL
ILALICVTQPFNPLAQFIFLMLLWGGALIVRRMPGRFSALMLIVLSLTVSCRYIWWRYTSTLNWDDPVSLVCGLILLFAE
TYAWIVLVLGYFQVVWPLNRQPVPLPKDMSLWPSVDIFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGREEFR
QFAQNVGVKYIARTTHEHAKAGNINNALKYAKGEFVSIFDCDHVPTRSFLQMTVGWFLKEKQLAMMQTPHHFFSPDPFER
NLGRFRKKPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIAVETVTEDAHTSLRLHRRGYTSAYMRIPQAA
GLATESLSAHIGQRIRWARGMVQIFRLDNPLTGKGLKFAQRLCYVNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPAL
MIALFVLPHMIHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGGLVEEEYVDWVISRPYI
FLVLLNLVGVAVGIWRYFYGPPTEMLTVVVSMVWVFYNLIVLGGAVAVSVESKQVRRSHRVEMTMPAAIAREDGHLFSCT
VQDFSDGGLGIKINGQAQILEGQKVNLLLKRGQQEYVFPTQVARVMGNEVGLKLMPLTTQQHIDFVQCTFARADTWALWQ
DSYPEDKPLESLLDILKLGFRGYRHLAEFAPSSVKGIFRVLTSLVSWVVSFIPRRPERSETAQPSDQALAQQ
>SEQF1516_EDU88092.1 sugar transporter, glycoside-pentoside-hexuronide (GPH):cation symporter family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSEVLSVKEKIGYGMGDAASHIIFDNVMLYMMFFYTDNFGIPAGFVGTMFLVARALDAISDPCMGLLADRTRSRWGKFR
PWVLCGALPFGIVCVLAYSTPDLSMNGKMIYAAITYTLLTLLYTVVNIPYCALGGVITNDPTQRISLQSWRFVLATAGGM
LSTVLMMPLVNLIGGDNKPLGFQGGIAVLSVVAFMMLAFCFFTTKERVEAPPTTTSMREDLRDIWQNDQWRIVGLLTIFN
ILAVCVRGGAMMYYVTWILGTPEVFVAFLTTYCVGNLIGSALAKPLTDWKCKVTIFWWTNALLAVISLAMFFVPMQASIT
MFVFIFVIGVLHQLVTPIQWVMMSDTVDYGEWCNGKRLTGISFAGTLFVLKLGLAFGGALIGWMLAYGGYDAAEKAQNSA
TISIIIALFTIVPAICYLLSAIIAKRYYSLTTHNLKTVMEQLAQGKRRCQQQFTSQEVQN
>SEQF1516_EDU88093.1 MFS transporter, metabolite:H+ symporter (MHS) family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATAAVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIG
SAVFGHFGDRVGRKATLVASLLTMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVSLHESPVFEKVAKAKKQVKIPLG
TLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFSTAAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKS
MVIITTLIILFALFAFNPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVASILGASVAPY
IAAWLQTNYGLSAVGLYLAAMAGLTLIALLLTHETRHQSL
>SEQF1516_EDU88094.1 hypothetical protein ECH7EC4501_0795 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRSLELRVCIAHKSIPAQVGQGMKYCCRMALHAEAQHHRVWLLIIR
>SEQF1516_EDU88095.1 PTS system, alpha-glucoside-specific IIBC component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSQIQRFGGAMFTPVLLFPFAGIVVGLAILLQNPMFVGESLTDPNSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLA
KQAQGRACLAVMVSFLTWNYFINAMGMTWGSYFGVDFTQDAVAGSGLTMMAGIKTLDTSIIGAIIISGIVTALHNRLFDK
KLPVFLGIFQGTSYVVIIAFLVMIPCAWLTLLGWPKVQMGIESLQAFLRSAGALGVWVYTFLERILIPTGLHHFIYGPFI
FGPAAVEGGIQMYWAQHLQEFSLSAEPLKSLFPEGGFALHGNSKIFGAVGISLAMYFTAAPENRVKVAGLLIPATLTAML
VGITEPLEFTFLFISPLLFAVHAVLAASMSTVMYLFGVVGNMGGGLIDQVLPQNWIPMFSNHADMMLTQIAIGLCFTLLY
FVVFRTLILQFNMCTPGREDAEVKLYSKAEYKASRGQTTAAEPKKELDQAAGILQALGGVGNISSINNCATRLRIALHDM
SQTLDDEVFKKLGAHGVFRSGDAIQVIIGLHVSQLREQLDSLINSHQSAENVAITEAV
>SEQF1516_EDU88096.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAETAKANKLKRNEVNCGRDIAILHEENKKCWLPGLIPGWLAKNKFI
>SEQF1516_EDU88097.1 Beta-ketoacyl synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTRRVVITGMGGVTAFGENWQDVSARLLAYENAVRKMPEWQVYDGLHTLLGAPVDDFTLPEHYTRKRIRAMGRVSQMSTR
ASELALEQAGLIGDPILTSGETGIAYGSSTGSTGPVSEFATMLTEKHTNNITGTTYVQMMPHTTAVNTGLFFGLRGRVIP
TSSACTSGSQAIGYAWEAIRHGYQTVMVAGGAEELCPSEAAVFDTLFATSQHNDAPKTTPSPFDENRDGLVIGEGAGTLI
LEELEHAKARGATIYGEIVGFATNCDAAHITQPQRETMQYCMEQSLKIAGLSAQDIGYISAHGTATDRGDMAESLATATI
YGDNVPLSSLKSYFGHTLGACGALEAWMSLQMMREGWFAPTLNLNKPDPNCGALDYIMHEARKVDCEFLQSNNFAFGGIN
TSIIIKRWP
>SEQF1516_EDU88098.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGKLGENVPLLIDKAVDFMASSQAFREYLKKLPPRNAIPSGIPDESVPLYLQRLEYYRRLYRPKQVEGQ
>SEQF1516_EDU88099.1 major facilitator family transporter TsgA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSSMSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGF
LLMVLAVAGLMFSHSLALFSAAMFILGVVSGITMSIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSI
EWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVAKEKWGIGVLFLSVAALCYILGQLGFISWVPEYAKGLGMSL
NDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTVLAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQ
QTKVPSPKLVNFVLTCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTSH
>SEQF1516_EDU88100.1 low-affinity inorganic phosphate transporter 1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIYTRAMRSQLAVVMAAVFNFLGVLLGGLSVAYAIVHML
PTDLLLNMGSSHGLAMVFSMLLAAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLI
VSPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSAIGVAFSHGANDGQKGIGLVMLV
LIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQHPALLKQATGADQLVPAPEAGATQPAEFHCHPSNTINALNRLKG
MLTTDVESYDKLSLDQRSQMRRIMLCVSDTIDKVVKMPGVSADDQRLLKKLKSDMLSTIEYAPVWIIMAVALALGIGTMI
GWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVLSSSVAGTMVVDGGGLQRKTVTSILMAWVFT
LPAAVLLSGGLYWLSLQFL
>SEQF1516_EDU88101.1 outer membrane usher protein FimD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASSHLFITLASGICLLCSISAFARDSLFNPRLLELDHPADNIDIHQFNRSNTLPAGTYKVDVMINGMLFERQEVKFAQD
NPDAELHPCYVAIKNVLATYGIKVDAIKSLANVDDKTCVNPVPLIDGATWLLDASKLALNITIPQIYLNNAVNGYISPSR
WDQGINAMMMNYDFSASHTIRSNYDDDDDSYYLNLRNGINLGAWRFRNYSTLNSYDGNVDYHSVSNYIQRDIMALRSQIM
IGDTWTASDVFDSTQVRGVRLYTDDDMLPSSQNGFAPVVHGIAKTNATVIIKQNGYVIYQSAVPQGAFALTDLNTTSSGG
DLDVTIKEEDGSEQHFIQPFTSLAILKREGQTDVDLSIGEVRDESGFTPEVLQLQAMHGFPLGITLYGGTQLANDYASAA
LGIGKDMGALGAISFDVTHARSQFDYDDNESGQSYRFLYSKRFEDTNTTFRLVGYRYSMEGFYTLNEWVSRQDNDSDFWV
TGNRRSRFEGTWTQSFTPGWGNIYLTFSRQEYWQTDEVERLLQFGYNNNWRNISWNVSWNYTDSIKRSLGNHHDDNNDDF
GKEQIFMFSMSIPLSCWMEDSYVNYSLTQNNHHESTMQVGLNGTMLEGRNLSYNVQESWMHSPDDSYSGNAGMTYDGTYG
SVNGSYSWSRDSQHFDYGARGGVLVHSDGVTFSQELGETVALVKAPGAEGLSIENATGISTDWRGYTVKTQLSPYDENRV
ALNSDYFSKANIELENTVINLVPTRGAVVKAEFVTHVGYRVLFNVRQVNGKPIMFGAMATASLETGTVTGIVGDNGELYL
SGMPEKGEFLLSWGQAADEKCKAAYHITHKPDDTSLVQMDAICR
>SEQF1516_EDU88102.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRGLLAELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSF
SISYAGNMVGVALTTEGECGLDMELQRATRGFHSPHAPDNHTFSSNESLWVSKQNDPNEARAQLITLRRSVLKLTGDVLN
DDPRDLQLLPIAGRLKCAHVNHVEALCDAEDVLVWSVAVTPTIEKLSVWELDGKHGWKSLPDIHSRANNPTSRMMRFAQL
STMKAFSPN
>SEQF1516_EDU88103.1 carboxylate/amino acid/amine transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSQMSSQFLTMTRLIFAGLILLTLSFVHGDKIFSIINNHKDAISLLIFSV
VGALTVQLTFLLTIEKSNAATATVLQFLSPTIIVAWFSLVRKSRPGILVFCAILTSLIGTFLLVTHGNPTSLSISPAALF
WGIASAFTAAFYTTYPSTLIARYGTLPVVGWSMLIGGLILLPFYAGQGTNFIVNGSLILAFFYLVVIGTSLTFSLYLKGA
QLIGGPKASILSCAEPLSSALLSLLLLGITFTLPDWLGTLLILSSVILISMDSRRRARKINRPARHE
>SEQF1516_EDU88104.1 SepL [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANGIEFNQNPASVFNSNSLDFELESQQLTQKNSSNISSPLINLQNELAMITSSSLSETIEGLSLGYRKGSARKEEEGST
IEKLLNDMQELLTLTDSDKIKELSLKNSGLLEQHDPTLAMFGNMPKGEIVALISSLLQSKFVKIELKKKYARLLLDLLGE
DDWELALLSWLGVGELNQEGIQKIKKLYEKAKDEDSENGASLLDWFMEIKDLPEREKHLKVIIRALSFDLSYMSSFEDKV
KTSSIISDLCRVIIFLSLDNYADIISISIKKDKDIILNEVLSIIEHVWLTEDWLLESPSRVSIVEDKHIYYFHLLKDFFT
SLPDACFIDSEQRENALLMIGKVIDYKEEII
>SEQF1516_EDU88105.1 L-seryl-tRNA selenium transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQMLDEAREVIRGSQTLPAWCENWAQEVDARLTKEAQSAL
RPVINLTGTVLHTNLGRALQAEAAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLM
LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAID
EAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEPMPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPL
KRALRADKMTLAALEATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLSQIGSGSLP
VDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRCLEDEQRFLEMLLK
>SEQF1516_EDU88106.1 single stranded DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAQIAAYGRLVDDPQVKQTSKGTAMTLARMAVSLPCSQAQDGQATLWLSVLAFGKQADAVARHEKGDLISVAGNMQISQ
WTGQNGETRQGWQVIADSVISARSARPGGKRGQQGKATEAQERAKRQTGQQGNQPPAGGDDPFSDDIPF
>SEQF1516_EDU88107.1 DNA replication and repair protein RecF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIYTLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERE
TAIGLTKDKQGDSKVRIDGTDGHKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQ
RNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTFSFQRGWEKETEYAEVLERNFER
DRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKLLMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRL
KATQSQVFVSAISAEHVIDMSDENSKMFTVEKGKITD
>SEQF1516_EDU88108.1 regulatory protein UhpC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLPFLKAPADAPLMTDKHEIDARYRYWRRHILLTIWLGYALFYFTRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGV
SKFVSGIVSDRSNARYFMGIGLIATGIINILFGFSTSLWAFAVLWVLNAFFQGWGSPVCARLLTAWYSRTERGGWWALWN
TAHNVGGALIPIVMAAAALHYGWRAGMMIAGCMAIVVGIFLCWRLRDRPQALGLPAVGEWRHDALEIAQQQEGAGLTRKE
ILTKYVLLNPYIWLLSFCYVLVYVVRAAINDWGNLYMSETLGVDLVTANTAVTMFELGGFIGALVAGWGSDKLFNGNRGP
MNLIFAAGILLSVGSLWLMPFASYVMQATCFFTIGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLGASLAGWPL
AKVLDTWHWSGFFVVIAIAAGISALLLLPFLNAQTPREA
>SEQF1516_EDU88109.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEIVIRHAETRDYEAIRQIHAQPEVYYNTLQVPHPSDHMWQERLADRPGIKQLVACIDGDVVGHLTIDVQQRPRRSHVA
DFGICVDARWKNRGVASALMREMIEMCDNWLRVDRIELTVFVDNAPAIKVYKKFGFEIEGTGKKYALRNGEYVDAYFMAR
VK
>SEQF1516_EDU88110.1 secreted protein EspD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNVNNDTLSVTSGVNTASGTSGITQSETGLSLDLQLVKSMNSSAGWTESSPLPTPPAGHSLVTPSAAEDVLSKLFGGIS
GEVTSRTEEAEPQRTSYPYLSQVNTVDPQQMMMMVTLLSLDTSAQKVSSLKNSNEIYMDGQTKALENKTQEYKKQLEEQQ
KAEEKSQKSKIVGQVFGWLGVALTAVAAVFNPALWAVVAIGATAMALQTAVDVMGENAPQGLKTAAQVFGGISMAASILT
AGVGGVSSLLSKFGNVANKIGSSVVKVVEKAAEALVKNVFAKISTVAEGVTNGIRSAGTTALNNEAAQLQMLSQLAAFAV
QNLTRQSESLGESAKLELDKAASELQNQASYLQSVSQLMSDSARVNSRIVSGRI
>SEQF1516_EDU88111.1 sn-glycerol-3-phosphate transport ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKSTLLRMVAGLERVTEGDICINDQRVTEMEPKDRGIAM
VFQNYALYPHMSVEENMAWGLKIRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVRDPAVFLFDE
PLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGTPVEVYEKPASLFVASFIGSPAM
NLLTGRVNNEGTHFELDGGIALPLNGGYRQYAGRKMTLGIRPEHIALSSQAEGGVPLVMDTLEILGADNLAHGRWGEQKL
VVRLAHQERPTAGSTLWLHLPENQLHLFDGETGQRV
>SEQF1516_EDU88112.1 outer membrane heme/hemoglobin receptor ChuA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSRPQFTSLRLSLLALAVSATLPTFAFATETMTVTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDG
TGRTNGQDVNMRGYDHRGVLVLVDGVRQGTDTGHLNGTFLDPALIKRVEIVRGPSALLYGSGALGGVISYDTVDAKDLLQ
EGQSSGFRVFGTGGTGDHSLGLGASAFGRTENLDGIVAWSSRDRGDLRQSNGETAPNDESINNMLAKGTWQIDSAQSLSG
LVRYYNNDAREPKNPQTVGASESSNPMVDRSTIQRDAQLSYKLAPQGNDWLNADAKIYWSEVRINAQNTGSSGEYREQIT
KGARLENRSTLFADSFASHLLTYGGEYYRQEQHPGGATTGFPQAKIDFSSGWLQDEITLRDLPITLLGGTRYDSYRGSSD
GYKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEMYNDSKHFSIGRFYTNYWVPNPNLRPETNETQEYGFGLR
FDDLMLSNDALEFKASYFDTKAKDYISTTVDFAAATTMSYNVPNAKIWGWDVMTKYTTDLFSLDVAYNRTRGKDTDTGEY
ISSINPDTVTSTLNIPIDHSGFSVGWVGTFADRSTHISSSYSKQPGYGVNDFYVSYQGQQALKGMTTTLVLGNAFDKEYW
SPQGIPQDGRNGKIFVSYQW
>SEQF1516_EDU88113.1 4'-phosphopantetheinyl transferase acpT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYRIVLGKVSTLSAAPLPPGLREQAPQGPRRERWLAGRALLSHTLSPLPEIIYGEQGKPAFAPETPLWFNLSHSGDDIAL
LLSDEGEVGCDIEVIRPRANWRWLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQIVSVDSTYHSS
LSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN
>SEQF1516_EDU88114.1 PEP-dependent sugar transporting PTS family, IIB component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQTILFVCATGIATSTAVTEKVMEYCKEQGLNVNYSQTNVASLPGNTDGVALVVSTTKVPYELDVPVVNGLPIITGIGE
EKVLAQIVSILKK
>SEQF1516_EDU88115.1 ribulose-phosphate 3-epimerase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVPNLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPD
FAAAGASIITFHPEASEHVDRTLQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDEMRSELAKVSHE
>SEQF1516_EDU88116.1 arsenical pump membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAA
LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFV
LEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAA
TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWG
YYFRTGIIMTLPVLFVTLAALALRLSFTL
>SEQF1516_EDU88117.1 hypothetical protein ECH7EC4501_0956 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGGKGRDAPDACPLVGGGGAGREGVNEVTWLLTLKIVLALTFDEPGEKGE
>SEQF1516_EDU88118.1 nitrite transporter NirC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIILIFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELF
TGHTMFLTFGVKAGTISHGQMWAILPQTWLGNLVGSVFVAMLYSWGGGSLLPVDTSIVHSVALAKTTAPAMVLFFKGALC
NWLVCLAIWMALRTEGAAKFIAIWWCLLAFIASGYEHSIANMTLFALSWFGNHSEAYTLAGIGHNLLWVTLGNTLSGAVF
MGLGYWYATPKANRPVADKFNQTETAAG
>SEQF1516_EDU88119.1 hypothetical protein ECH7EC4501_0804 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGLNFPACAENVLATATATTEIEKEEKVRETVFRDIELFLLKRY
>SEQF1516_EDU88120.1 EscS protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPFLLKIIAVFATLALTYHWMGTTIINFSSIIFEMIPKVNG
>SEQF1516_EDU88121.1 2-amino-3-ketobutyrate coenzyme A ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRGEFYQQLTNDLETARAEGLFKEERIITSAQQADITVADGSHVINFCANNYLGLANHPDLIAAAKAGMDSHGFGMASVR
FICGTQDSHKELEQKLAAFLGMEDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMQE
LEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFVGENGRGSHEYCDVMGRVDIITG
TLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNSLAPAIVAASIKVLEMVEAGSELRDRLWANARQFREQMSAAGFTL
AGADHAIIPVMLGDAVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGKQLGVIA
>SEQF1516_EDU88122.1 transcriptional regulator domain protein, TetR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVSEAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKD
EKDTTARLRLIVLLLLGFGERNPGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLAS
QILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ
>SEQF1516_EDU88123.1 thermoresistant gluconokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYCGGTTLSTTNHDHHIYVLMGVSGSGKSAVASEVAHQLHAAFLDGDFLHPRRNIEKMASGEPLNDDDRKPWLQALNDAA
FAMQRTNKVSLIVCSALKKHYRDLLREGNPNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLV
VDIDQPLEGVVASTIEVIKKGK
>SEQF1516_EDU88124.1 FinO protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQQTTQQDQTTRKPSRRIPWQHMTKRQRKNRRRINRLAEYWPELFGAENIKPLKAGVIHDMLQDAKARELAIGHGVLRG
ALTSHLHTTRYLKAIIAGGPRYDLNGQPCGEVTEKEKAAASEQLMWRLEQIKQQNIQRQDTGGGESDNRQRGTET
>SEQF1516_EDU88125.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFLNYFALGVLIFVFLVIFYGIIAIHDIPYLIAKKRNHPHADAIHTAGWVSLFTLHVIWPFLWIWATLYQPERGWGMQSH
VASQEKATDPEIASLSDRISRLEHQLAAEKKTDYSTFPEI
>SEQF1516_EDU88126.1 integral membrane protein, YccS/YhfK family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVPACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQLL
LAKDVPLPFLLTGLTLVLGVTAELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLSAQNNTDYKRMLRIFQEALDLQE
HISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARLRVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWH
FSRIARVLRTQKPLYARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWILMTVLLVT
QNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASYLILRKNYGWATVGFTITAVYTLQLLWLNGE
QYILPRLIDTIIGCLIAFGGTVWLWPQWQSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLN
QAMQEPAFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQRLEYDEPGSSGDANIM
DAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPHHGIWLSRKLRDSKA
>SEQF1516_EDU88127.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFKTKWFAREARSHAITDEELCRAILETEQGKADALGGGVFKKRLHQNRERAIILAKGVSNWFYTFLYAKQDMSNINSQE
LAGFREIAKHYAFLTKAQLTAMINTKELTEICYDCKN
>SEQF1516_EDU88128.1 carbohydrate kinase, FGGY family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPDNSAAIVIDIGTTNCKVTCFSCLDATTLGAHKFVTAKQISPQGDVDFDIDALWQEVRQAIAQLNAASPLPVRRISIAS
FGESGVFLDEHGEILTPMLAWYDRRGEEYLATLSEADSAALYDICGLPLHSNYSAFKMRWLLEHYPLRNRRGLRWLHAPE
VLLWRLTGEQHTDITLASRTLCLDVRKGEWSAKAAALLHVPCTAFAPLVQPGEHAGWVSESLCKTLGFSQPVSVTLAGHD
HMVGARALQMMPGDILNSTGTTEGILQLDTQPTLDEQAKRDKLANGCYSLANQFTLFASLPVGGFALEWLRNTFRLTDEE
IAASLTRGHADYLAGNWLLDDIPVFIPHLRGSGSPYKNRHTRGLFYGLGDTLSIDMLIASVSLGLTMEFANCFACFNVPG
TSALKVIGPATHNPLWLQLKADILQRPVEAIAFNEAVSVGALLTAAPDIPPPPVAIAQRLLPNRARYHQLQRYQHKWKSW
YQLKLQQEGVMPLHHREEHYVE
>SEQF1516_EDU88129.1 transcriptional regulator GadW [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTHVCSVILIRRSFDIYHEQQKISLHNESILLLEKNLADDFAFCSPDTRRLDIDELTVCHYLQNIRQLPRNLGLHSKDRL
LINQSPPMPLVTAIFDSFNESGVNSPILSNMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAE
RMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYFINTFRQYYGVTPHQFAQHSPGT
FS
>SEQF1516_EDU88130.1 phosphoenolpyruvate carboxykinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGYERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRD
TFWWADKGKGKNDNKPLSPETWQHLKGLVTKQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEEL
AGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSMMNYLLPLKGIASMHCSANVSEK
GDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDDGVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGT
IDFDDGSKTENTRVSYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLAGTERGITE
PTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRISIKDTRAIIDAILNGSLDNAETFTLPMFNL
AIPTELPGVDTKILDPRNTYASPEQWQEKAETLAKLFIDNFDKYTDTPAGAALVAAGPKL
>SEQF1516_EDU88131.1 sn-glycerol 3-phosphate transport protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQAVYAAPMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNS
FVMAFSITLGKITVSMLSAFAIVWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATF
LFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWPLLIITDVDLGTTVAGIKGMIAT
GEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGLVDSEK
>SEQF1516_EDU88132.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIREAQRSELPAILELWLESTTWGHPFIKVNYWRECIPLVRDAYLANAKNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKA
VRRGIGKALMQYVQQRYPHLMLEVYQKNQPAIDFYQAQGFHIVDCAWQDETQLPTWIMSWPVVQTL
>SEQF1516_EDU88133.1 xanthine permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLLAMFVAVITPALLICQALGLPAQDTQHIISMSLFASG
VASIIQIKAWGPVGSGLLSIQGTSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPL
VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNPYLRVASLVIAMAAGYALAWFMG
MLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLMLVFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNS
FVSAVFNTFPNSCFGQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIAASGVRIVS
REPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGITAIVLNLIFPPEKQ
>SEQF1516_EDU88134.1 HicB family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKLKTPNSMEIAGQPAVITYVPELNAFRGKFLGLSGYCDFVSDSIQGLQKEGELSLREYLEDCKAAGIEPYARTEKIKT
FTLRYPESLSERLNNAAAQQQVSVNTYIIETLNERLNHL
>SEQF1516_EDU88135.1 glycyl-tRNA synthetase, beta subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGTVQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQA
FDAEGKPSKAAEGWARGCGITVDQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRP
VHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIADYEERKAKIKADAEEAARKIGGN
ADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPSEALVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNE
KVVRPRLADAEFFFNTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLLSKCDLMTN
MVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVACALAIADKMDTLAGIFGIGQHPKGDKDPFAL
RRAALGVLRIIVEKNLNLDLQTLTEEAVRLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADF
DARMKAVSHFRTLEAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDKLEPYFAEGRYQDALVE
LAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRVADISLLQ
>SEQF1516_EDU88136.1 thioesterase superfamily protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNDPRFTAEVELTIPFHDVDMMGVAWHGNYFRYFEVAREALLNQFNYGYRQMKESGYLWPVVDARVKYRHALTFEQRIR
VRAHIEEFENRLRIGYQIFDAETGKRATTGYTIQVAVDEQSRELCFVSPDILFERMGVKP
>SEQF1516_EDU88137.1 NAD(+)-dependent DNA ligase LigB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPSPRCISASLTTAEVKMKVWMAILISILCWQSSVWAVCPAWSPARAQEEIFRLQQQIKQWDDDYWKEGKSEVEDGVYDQ
LSARLTQWQRCFVSEPRDVMMPPLNGAVMHPVAHTGVRKMADKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAI
SRGNGLKGEDWTQKVSLISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSLGVFVW
AWPDGPQLMTDRLKELATAGFTLTQRYTRAVKNADEVARVRNEWWKAKLPFVTDGVVVRGAKEPESRHWLPGQAEWLVAW
KYQPVAQVAKVKAIQFAVGKSGKISVVASLAPVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWR
GAERTKPTPPENRFNSLTCYFASDVCQEQFISRLVWLGSKQVLGLDGIGEAGWRALHQTHRFEHIFSWLLLTPEQLQNTP
GIAKSKSAQLWHRFNLARKQPFTRWVMAMGIPLTRAALNASDERSWSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQI
KKLGSWLAAQQITGFEP
>SEQF1516_EDU88138.1 protein bax [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILTPIRRYGAMILMLLTLVFSSEVLAKTHTTTASQKSHLTKASNKQVSSKQEYSRNSAKSSSLPDLRKYPSGTSRKKAF
LRTVMPYITSQNAAITAERNWLISKQYQGQWSPAERARLKDIAKRYKVKWSGNTRKIPWNTLLERVDIIPTSMVATMAAA
ESGWGTSKLARNNNNLFGMKCMKGRCTNAPGKVKGYSQFSSVKESVSAYVTNLNTHPAYSSFRKSRAQLRKADQEVTATA
MIHKLKGYSTKGKSYNNYLFAMYQDNQRLIAAHM
>SEQF1516_EDU88139.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKFIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISISKIIGGCGPTAQ
>SEQF1516_EDU88140.1 hypothetical protein ECH7EC4501_0841 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQIKRIKPSIIYRLLLIVLGIPMVIYGLVCPLTIETRD
>SEQF1516_EDU88141.1 auxiliary transport protein, membrane fusion protein (MFP) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKSKRHLAWWGVGLLAVAAIVAWWLLRPAGVPEGFAVSNGRIEATEVDIASKIAGRIDTILVKEGQFVREGEVLAKMDT
RVLQEQRLEAIAQIKEAQSAVAAAQALLEQRQSETRAAQSLVNQRQAELDSVAKRHTRSRSLAQRGAISAQQLDDDRAAA
ESARAALESAKAQVSASKAAIEAARTNIIQAQTRVEAAQATERRIAADIDDSELKAPRDGRVQYRVAEPGEVLAAGGRVL
NMVDLSDVYMTFFLPTEQAGTLKLGGEARLILDAAPDLRIPATISFVASVAQFTPKTVETSDERLKLMFRVKARIPPELL
QQHLEYVKTGLPGVAWVRVNEELPWPDDLVVRLPQ
>SEQF1516_EDU88142.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMKLALTLEADSVNVQALNMGRIVVDIDGVNLAELINMVCDNGYSLRVVDESDRTSADCTPPFTALTGIRCSTAHITETD
NAWLYSLSHQTSDFGESEWIHFTGNGYLLRTDAWSYPVLRLKRLGLSKTFRRLVVTLIRRYGVSLIHLDASAGCLPGLPT
FNW
>SEQF1516_EDU88143.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVAKLKPDVFVNTNPFLEAMYKERLSHKGYSDKIALSINDKKYNVNSKDIENILDGKGDLFKKRTLWEFVRDLFPGSHIK
EVKGLIYEFVTKVDNKAEVFDKIKSLAKKEQQWRFSTKTDFTTNENNEVIVSRSFNLYTGATSNDNEKKQVSSERLTLDN
YLDDLHFDNSPLVRLTFDNYSVKLATLIKNKIPIINTTINLSSLSKDVLNSLKYCSFKNVIFSGVINSPNLEGPVFENCY
FDDCKFNNIQLYETNDDTVESGNKKPIKGMFKGCFISKCKIENYRCETSKIYTVTQPDSIQEKLGSYLFMQSFVQDCIIQ
GGCCPGSSILLSHFYNCNIIGLDAHGMDFLANSFNKSNYDEIRGPDTGTVFYNCNLKHIKINDGLREDGSDRTMFNPKEY
FSDYIERRSRNLKLDDNFSKCVESIKKGTDSSFSKKNTENNNVFFKNSNLIGANLGYYYSGDRCKDCAIDPNTNYSKDGL
TAQKYMYMDLDGAISKEQIPDFLKKVSAINIDVINFYNSESKTKEKYKNAFLELESFLSTLYVENKSYEEKYHFDNSRVE
FFIFKDMQENAQNIINNMIESDRIKFVESIINKMIPPPDGTILTENPKEYVQKQIKESHKESATNVTFDYKELAPIFEGV
EEKQIKALSNQLEHIKSFKTDYDSRLNKYARDFYYFSSAFAINWEDLLKNYQEIRASIKDYDDLLREIKELIISRNKSLE
DKRTLFDNKRDNWNSIEVQDEVNALNAKIVDCDDKIRSKLTIVRNNRLENQYKDDKNISDAMRNILDWFERYPDIVQNIT
QA
>SEQF1516_EDU88144.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRKLTPEERSAVENYLESLTQVLQVPGPTGASAAPISLA
LNAESNNVMMLTHAITRYGISTDDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQETR
GYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFFCLITPDVFVPWLAGGALLLLGA
GLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQEQINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHLVRQG
RYLSLHDEVKNFPLQHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRVGDTLRISG
TGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATALTEAVNRQLHPKPEDESRVSASLRSAIQKSG
MVLLDDFGDIVLKTADLCSAKDDCVRLKNALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFIT
HETARAAQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNAEGIVTKIFTDANGTQH
IGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQRHRTRMMKIQAYYESCLNPQLITPSESLIE
>SEQF1516_EDU88145.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIKSTFWRAFALTATLILTGCSHSQPEQEGRPQAWLQPGTRITLPAPGISPAVNSQQLLTGSFNGKTQSLLVMLNADDQK
ITLAGLSSVGIRLFLVTYDAQGLRAEQSIVVPQLPPASQVLADVMLSHWPISAWQPQLPAGWTLRDNGDKRELRNASGKL
VTEITYLNRKGKRVPISIEQHVFKYHITIQYLGD
>SEQF1516_EDU88146.1 oxidoreductase, NAD-binding [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQAPIYSHIHFTSDLNEVLNDPDVKLVVVCTHADSHFE
YAKRAMEAGKNVLVEKPFTPTLAQAKELFALAKSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGDLKAIVKTSHLVKIDYPKFIVHG
KKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGVLEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITHGAPNYVKES
EVLTNLEILERGFEQASPSTVTLAK
>SEQF1516_EDU88147.1 OsmC family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQARVKWVEGLTFLGESASGHQILMDGNSGDKAPSPMEMVLMAAGGCSAIDVVSILQKGRQDVVDCEVKLTSERREEAPR
LFTHINLHFIVTGRDLKDAAVARAVDLSAEKYCSVALMLEKAVNITHSYEVVAA
>SEQF1516_EDU88148.1 peptidase, M16 (pitrilysin) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQGTKIRLLAGGLLMMATAGYVQADALQPDPAWQQGTLSNGLQWQVLTTPQRPSDRVEIRLLVNTGSLAESTQQSGYSHA
IPRIALTQSGGLDAAQARSLWQQGIDPKRPMPPVIVSYDTTLFNLSLPNNRNDLLKEALSYLANATGKLTITPETINHAL
QSQDMVATWPADTKEGWWRYRLKGSTLLGHDPADPLKQPVEAEKIKDFYQKWYTPDAMTLLVVGNVDARSVVDQINKTFG
ELKGKRETPAPVPTLSPLRAEAVSIMTDAVRQDRLSIMWDTPWQPIRESAALLRYWRADLAREALFWHVQQALSASNSKD
IGLGFDCRVLYLRAQCAINIESPNDKLNSNLNLVARELAKVRDKGLPEEEFNALVAQKKLELQKLFAAYARADTDILMGQ
RMRSLQNQVVDIAPEQYQKLRQDFLNSLTVEMLNQDLRQQLSNDMALILLQPKGEPEFNMKALQAAWDQIMAPSTAAATT
SVATDDVHPEVTDIPPAQ
>SEQF1516_EDU88149.1 hypothetical protein ECH7EC4501_0906 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMPDIRNAAALYIDTADTFAQLSLNHSDYMHHIVSHFAAERMKHVKHYQKEVLLNYRAGGPVWREYPHDAGMAGKTKAT
TEGSPMEIKEIKRITNYAMSVAGGQGYQPGGRFLVAFNRRGYFSTKSSRANRVGLVSGSGLSNNLLCRCAFSRCRSSMDN
AISCNSSFVIVCTRKAVRCSTSYHSAGIFYGCNLRDDSGRFATHCININNVMLLCAFKENAGIFRTNFSRNTSDHLSKKA
AYTEAIPYKTGIGIGLPLELEAIHDAPASFFLYRRTRTPQQWWAVWNFLREGWFPLTPVRPIPYSPPPARLASWAVGIIP
KSEEPFTWLYPHALTLSGALCSA
>SEQF1516_EDU88150.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPESKEAPINIRAKASQRDLIDMAANLVAKSRTDFMLDAACREAQDILLDQRLFILDDEQYDAFLAALDAPITAERQAK
INALMNRKSPWE
>SEQF1516_EDU88151.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKICLIDETGTGDGALSVLAARWGLEHDEDNLMALVLTPEHLELRKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAK
AVGIKGDYLPDVVDATAGLGRDAFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTD
ITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVKRPDYAPPLANVATPNAVVTKGH
RFDIYAGTPV
>SEQF1516_EDU88152.1 cadmium-translocating P-type ATPase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSTPDNHGKKAPQFAAFKPLTTVQNANDCCCDGACSSTPTLSENVSGTRYSWKVSGMDCAACARKVENAVRQLAGVNQVQ
VLFATEKLVVDADNDIRAQVESAVQKAGYSLRDEQAADEPQASRLKENLPLITLIVMMAISWGLEQFNHPFGQLAFIATT
LVGLYPIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEGWAASRARQGVSALMALKPETAT
RLRNGEREEVAINSLRPGDVIEVAAGGRLPADGKLLSPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSE
PGASAIDRILKLIEEAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFATSWQEWIYKGLTLLLIGCPCALVIST
PAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTAIHPATGISESELLTLAAAVEQGATHPLAQA
IVREAQVAALAIPAAESQRALVGSGIEAQVNGERVLICAAGKHPADAFAGLINELESAGQTVVLVVRNDDVLGIIALQDT
LRADAATAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTELNQHAPLAMVGDGINDAPAMKAAA
IGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANIRQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVL
VTANALRLLRRR
>SEQF1516_EDU88153.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAQTEAFTRQTFNPIAFMGASNVFLGDCKTDTGMPQRIQAAENGNLRRASPLWLLEDECELTGS
>SEQF1516_EDU88154.1 RtcB protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNYELLTTENAPVKMWTKGVPVEADARQQLINTAKMPFIFKHIAVMPDVHLGKGSTIGSVIPTKGAIIPAAVGVDIGCGM
NALRTALTAADLPENLAELRQAIETAVPHGRTTGRCKRDKGAWENPPVNVDAKWAELEAGYQWLTQKYPRFLNTNNYKHL
GTLGTGNHFIEICLDESDQVWIMLHSGSRGIGNAIGTYFIDLAQKEMQETLETLPSRDLAYFMEGTEYFDDYLKAVAWAQ
LFASLNRDVMMENVVTALQSITQKTVRQPQTLAMEEINCHHNYVQKEQHFGEEIYVTRKGAVSARAGQYGIIPGSMGAKS
FIVRGLGNEESFCSCSHGAGRVMSRTKAKKMFSVEDQIRATVHVECRKDAEVIDEIPMAYKDIDAVMAAQSDLVEVIYTL
RQVVCVKG
>SEQF1516_EDU88155.1 shikimate kinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGDLFSCQTRWSIEIIFSLTLAISYEVSVHVLRSSLSEAGLSLTNSLSSTEKMAEKRNIFLVGPMGAGKSTIGRQLAQQL
NMEFYDSDQEIEKRTGADVGWVFDLEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVYLETTIE
KQLARTQRDKKRPLLHVETPPREVLEALANERNPLYEEIADVTIRTDDQSAKVVANQIIHMLESN
>SEQF1516_EDU88156.1 DNA-damage-inducible protein D [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEHHQPFEEIRHYGTEGQEFWSARELAPLLDYRDWRNFQKVLARATQACEASNQAASDHFVETTKMVVLGSGAQRELED
VHLSRYACYLVVQNGDPAKPVIAAGQTYFAIQTRRQELADDEAFKQLREDEKRLFLRNELKEHNKQLVEAAQQAAVATAT
DFAIFQNHGYQGLYGGLDQKAIHQLKGLKKSQKILDHMGSTELAANLFRATQTEEKLKRDGVNSKQQANTTHFDVGSKVR
QTIQELGGTMPEELPTPQVSIKQLENSVKITEKK
>SEQF1516_EDU88157.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLGVGLTGIIEVCNILITPTIYLLLNVFMLTLGAIIIFFSGRVWAGDSAPENREIAVWRQCFFLLPALLTLVGWIITLHL
ADYQFRQMGAGWLANLMLPWLGVFLVSLVGGEYWWMVIIPVGAHISFSLGYAWPTRYPLSGTSGLRCRNLLLFLLLLLGI
VAGYQAHLYKQQNPGVGVRENIDIRAWRPDKLNNRLTPLRGKPQIQFRQNWPRIDGATAAYPIYASAFYALSVIPEDFHV
WEYLENSRTPDAYNRIVKGDADIIFVAQPSGGQKKRAEESGVTLLYTPFAREAFVFIVNADNPVNSLTEQQVRDIFSGAI
TNWRTVGGNDQEIQTWQRPEDSGSQTVMQSQVMKKVRMISPQETEVASVMEGMIKVVAEYRNTNNAIGYTFRYYATQMNA
DKNIRLLAINGITPTAENIRNGKYAYIVDAFMVTRENTTSETQKLVEWFLTPQGQSLVEDVGYVPLYLTME
>SEQF1516_EDU88158.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKEVEKNEIKRLSDRLDAIRHQQADLSLVEAADKYAELEKEKATLEAEIARLREVHSQKLSKEAQKLMKMPFQRAITKKE
QADMGKLKKSVRGLVVVHPMTALGREMGLQEMTGFSKTAF
>SEQF1516_EDU88159.1 beta-ketoacyl synthase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFALNILDWQARAPGLSETLQWQEWSRQPQAIDPTAPLAKLSELPMMTARRLSSGSKLAVECGLAMLRRHQPDAVLYTS
RHGELERNYRIVHALATEQALSPTDFALSVHNSSVGNLTIAAKQPSVSSSLSAGRDSFQQGLCEVLSLLQAGYQRVLMVD
FDGFLPEFYHPQLPSEMPTWPYAVALVIEAGDDWQCETQSAIAGNETTLPQSMLFLQHYLQNVDTFSLPGERVQWRWSHR
>SEQF1516_EDU88160.1 hypothetical protein ECH7EC4501_0763 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAYHDCGKSRIECSENEKQHEICIFINSIDISALYFLTG
>SEQF1516_EDU88161.1 hexose phosphate transport protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYLIRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGV
GKTLVSYYADGKNTKQFLPFMLILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF
LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPESYGLGKAEELFGEEISEEDKET
ESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRIGIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSD
LANGRRGLVACIALALIIATLGVYQHASNEYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKGTFAYLIGD
SFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERKIRREKKIQQLTVA
>SEQF1516_EDU88162.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDPVFSIGISSLWDELRHMPAGGVWWFNVDRHEDAISLANQTIASQAETAHVAVISMDSDPAKIFQLDDSQGPEKIKLFS
MLNHEKGLYYLARDLQCSIDPHNYLFILVCANNAWQNIPAERLRSWLDKMNKWSRLNHCSLLVINPGNNNDKQFSLLLEE
YRSLFGLASLRFQGDQHLLDIAFWCNEKGVSARQQLSVQQQNGIWTLVQSEEAEIQPRSDEKRILSNVAVLEGAPPLSEH
WQLFNNNEVLFNEARTAQAATVVFSLQQNAQIEPLARSIHTLRRQRGSAMKILVRENTASLRATDERLLLACGANMVIPW
NAPLSRCLTMIESVQGQKFSRYVPEDITTLLSMTQPLKLRGFQKWDVFCNAVNNMMNNPLLPAHGKGVLVALRPVPGIRV
EQALTLCRPNRTGDIMTIGGNRLVLFLSFCRINDLDTALNHIFPLPTGDIFSNRMVWFEDDQISAELVQMRLLAPEQWGM
PLPLTQSSKPVINAEHDGRHWRRIPEPMRLLDDAVERSS
>SEQF1516_EDU88163.1 IS911 transposase orfB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTQNGVPMSRYRAGRLMKYLNLSSCQPGKHQYKNARQEHTCLPNLLERQFAVPEPDRVWCGDITYIWAGNRWCYLAVVM
DLFARRVIGWSLSANADTALISSALRMAYEVRGQPRDVMFHSDQGSQYTGLKYQQLLWRYRIKQSVSRRGNCWDNSPMER
FFRSLKTEWVPTDGYTGKDVARQQISSYILNYYNSVRPHHYNGGLTPEESENRYHFYCKTVASIT
>SEQF1516_EDU88164.1 hypothetical protein ECH7EC4501_0970 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEKFRTDLAHTFGIALEEQTDVLSFHDNDGHEWILECASQSEILFFYCYLLNSEPIQINSILEMNSNRELLGMFFLSLK
DDNILLNIAFPADKIDITEFANLMENGYLLKNEIIRSLSSRPTDFLP
>SEQF1516_EDU88165.1 type III secretion apparatus protein SpaR/YscT/HrcT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEIMTVIVSSFYCILRPLGMFIILPIFSTGVLLSNFIRNSIMIAFTLPIIVENYTFSEKLPSGIFQLTGIALKEISIGF
FIGLSFTILFWAIDAAGQIIDTLRGSTISSIFNPSISDSSSITGVILYQFISVIFVIHGGIQSILDKLYLSYEILPLQAD
IAFNRALIDFLFSLWDSFIKLMLSFSVPMIIGIFLCDMGFGFLNKTAPQLNVFTLSLPVKSLIAIFILLLVIHVFPDFIT
ANIHSDIIDRSLPSMINE
>SEQF1516_EDU88166.1 arsenical resistance operon repressor [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQPKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPSW
AAKIIEQAWRCEQEKVQVIVRNLARQNCSVDSKNTCS
>SEQF1516_EDU88167.1 putative coproporphyrinogen III oxidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNANNTLDLTPHFALDGDQPFKDRRAMMPFRGAIPVAKEQLAQTWQEMINQTASPRKRLVYLHIPFCATHCTFCGFYQNR
FNEDACAHYTDALIREIEMEADSVLHQSAPIHAVYFGGGTPSALSAHDLARIITTLREKLPLAPDCEITIEGRVLNFDAE
RIDACLDAGANRFSIGIQSFNSKIRKKMARTSDGPTAIAFMESLVKRDRAAVVCDLLFGLPGQDAQTWGEDLAIARDIGL
DGVDLYALNVLSNTPLGKAVENGRTTVPSPAERRDLYLQGCDFMDDAGWRCISNSHWGRTTRERNLYNLLIKQGADCLAF
GSGAGGSINGYSWMNERNLQTWHESVAAGKKPLMLIMRNAERNAQWRHTLQSGVETARVPLDELTPHAEKLAPLLAQWHQ
KGLSRDASTCLRLTNEGRFWASNILQSLNELIQVLNAPAIMREKP
>SEQF1516_EDU88168.1 type III secretion system protein, SsaH family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVNDISANKILVWAAVAAANHKLPKYAEAILNVFPQIIPDKKDIAHLEFIILFGLNRKNDAVKALEDCMDDETSQLLYSL
VHENGSGWVRGF
>SEQF1516_EDU88169.1 type III secretion apparatus protein, YscD/HrpQ family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLSSYKIKLLNGAMRNRELQLPMGNLTLGTEDNDIVYFPLEQGLNQFLLDIREEGVFLLSPVEFWIDGQPTPYEADKPLP
VGKVIDIAGCCFIIGDIDHSLPLSDVPERFSAKSRRKKRLILASVIGATFALSGAIGSYVLLSPKAEPPTFTRADVYQQL
KENKLHAITLVWHGKNIALYGRCESTTDLTPFFNYLKEKNIFYYNNIICNNQIISAINDVLTEYGYKDIIITKGNKPGFF
LLSGYIPPSPKWSEVENLLLNTPGVAGWEIHNNSNNKINELASEFKKNKLINYVNIFKKNDVIIVAGEVSQQNESKILAI
INAMNKNSNAKILFQNIQPYISADIFPGKILRISGTMKNPTIALDNGTSLGIGSILKGGYVIDAIDPKDGINISRPDEYI
HIPLSY
>SEQF1516_EDU88170.1 glycogen phosphorylase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNATLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFL
IGRTLSNAMLSLGIYEDVQGALEAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQIIPGYDTDATNTLRLWSAQASS
EINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTYSGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLN
DTHPVLSIPEMMRLLIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYFLKTLQEQY
PNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLFADFAKIFPGRFTNVTNGVTPRRWLAVANPS
LSAVLDEHLGRNWRTDLSLLNELQQHCDFPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLM
NVLHVITRYNRIKADLDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKVVFIPNYSVSLAQLIIP
AADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEMLDHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEEL
HQVLTQIGSGVFSPEDPGRYRDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEWTAKAMLNIANMGYFSSDRTI
KEYADHIWHIDPVRL
>SEQF1516_EDU88171.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHVSLQEFLKTEPDGTLEVVAEQYNTTLLEVVRNLPSSTVVPGDKFDTVWDTVCEWGNVTTLVHTADVILEFSGELPSG
FHRHGYFNLRGKHGMSGHIKAENCTHIALIERKFMGMDTASILFFNKEGSAMLKIFLGRDDHRQLLSEQVSAFHTLAASL
KEHA
>SEQF1516_EDU88172.1 Ler [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNMENNSHTTSPYIQLIEQIAVLQQEAKRLREQEVQSVIESIQKQITYYNITLQELGYTNVPDDGLARRNSSKGVYYRNE
EGQTWSGVGRQPRWLKEALLNGMKKEDFLVKDTEEEIIPLKNI
>SEQF1516_EDU88173.1 hypothetical protein ECH7EC4501_0594 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLMQIQPVKYRFTTLTFFDYFLKKAKYYCPDAIINPPFDSG
>SEQF1516_EDU88174.1 outer membrane lipoprotein carrier protein LolA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFLPLLALLISPFVSALTLDDLQQRFTEQPVIRAHFDQTRTIKDLPQPLRSQGQMLIARDQGLLWDQTSPFPMQLLLDD
KRMVQVINGQPPQIITAENNPQMFQFNHLLRALFQADRKVLEQNFRVEFADKGEGRWTLRLTPTTTPLDKIFNTIDLAGK
TYLESIQLNDKQGDRTDIALTQHQLTPAQLTDDERQRFAAQ
>SEQF1516_EDU88175.1 lipopolysaccharide 1,3-galactosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQLNDSDIILFEYNFHYQNIRSKNTLDIAFGIDRNFLFGCGVAIASILLNNREISCEFHVFTDYISDKDKLYFSDLAKQ
YNSRINIYVINCDKLKSLPSTKNWTYATYFRFIIADYFYHKHEKILYLDADIACKGSIKELLDYQFSTNEIAAVVAERDV
EWWQNRASVLTTPQLASGYFNAGFLLINIDEWNLNNISSKAIEMLRDPDWVSKITHLDQDVLNVLLNGKVKFISEKYNTR
YSINYELKDKVDNPVNDDTVFIHYVGPTKPWHEWADYPVSRSFLIAKAASPWSKEDLLKPVNSNQYRYCAKHKFKQKHYM
AGIFNYLKYYKEKCF
>SEQF1516_EDU88176.1 hypothetical protein ECH7EC4501_0655 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANKWSGFNPPGQLKQVCIRTNNPAELSCRVIDNLPA
>SEQF1516_EDU88177.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLKGIKDILLSLVDQKVNIYSVRQELLNFLNNDLYKNDGEILSYKESIMLFCAE
>SEQF1516_EDU88178.1 ABC transporter, iron chelate uptake transporter (FeCT) family, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGLSLLLLALVLFGASQGALKISFDALFDEEYRDIWLNIRLPRVLLAVLVGAALATAGVIMQGLFRNPMADPGLLGVSSG
SALMVGVAIVLPFSFPVVLVLYEQMVFAIAGSLVVCAIIFLITQRHRDGSMMQLLLAGIAINALCGAAIGILSYIGDEQQ
LRQLTLWMMGNLGQAQWPTLLVASSFILPAIIATTCLAGTLNLLQLGDEEAHYLGVNVKRKRQQLLLVSSLLVGAAVSVS
GIIGFIGLVIPHLIRMTTGANHRWLIPCSALAGACLLLMADTLARTLVQPAEMPVGLLTSLLGGPYFMWLILRNRRIT
>SEQF1516_EDU88179.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNLIGTPPNHAVPHNYIDMEQMEYLCHLNRFSKLSNDFLINGPREDLFTYKYVLDGSFSNLQHLLPKGQLQKIQQRLSS
LMHKNMFHCFHVFLLKLCSIESIPLPNADYAFFDDEMPFTLTDEQIENISFLNAYHKEKKGNNDIVTFDFMSADHHYNFS
TTIALTNDSFHISSINNHNSQVIFDENIHLHPYELPESSQWCYQLIKNMISLHCRYNNNFKIN
>SEQF1516_EDU88180.1 putative fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKILSGLILLLCCPYGFAANGDGATHMSNLSFGPLTVAAANNHSGYNIFEALSNTTGTYPVRCHCDDTHGGPGQQTAFF
PIFYTGDAAPGLVLERTLNGLNYYALNDYLSVGVTIFIINNQYAAIPFEHLSNQSTSPQHTCGAGNNGSTVNLDSGRSAK
LSFYVRHSITGTVTIPTTEVAWLYAGMSDHFPKTTPVSKVTIRGQLTAPQNCELTPNQSIDVDFQKINSAEFSSTAGSII
AERKIKTEVTVSCTGMEDVRSTEVVSASMIAANRSADATMIVTSNPDVGIKIFDKNDRPVNVDGGNLPADMGAISRLGKT
DGSVTFYSAPASLTGAKPAPDNGFTATATLVIEFTN
>SEQF1516_EDU88181.1 xylose operon regulatory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEEDFRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPI
VGVGGSYHLAESYPPVHYIATDNYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGIDNEELTRYLSRVALSSVAQGAR
QMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRSTDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEK
RFKEEVGETIHAMIHAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
>SEQF1516_EDU88182.1 1,4-alpha-glucan branching enzyme [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDATDVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFF
RYQLAVVWHGQQNLIDDPYRFGPLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWD
GRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETASLICGLPEKVVQTEERKKANQFD
APISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYAKWMGFTHLELLPLNEHPFDGSWGYQPTGLYAPTRRFGTRDDFRY
FIDAAHAAGLNVILDWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALYWIERFGID
ALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQVSGAVTMAEESTDFPGVSRPQDMGGLGFWYK
WNLGWMHDTLDYMKLDPIYRQYHHDKLTFGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAF
PGKKLLFMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPYGFEWLVVDDKERSVLI
FVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTDSMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLAT
IWLVREAE
>SEQF1516_EDU88183.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKRRKEPETLREHCRHIFGDEPPVLCVWETEFDYADAELKALAAKEWQQISEWDLSAYYVLNLVYNEPMQIELFRYLFP
LCLAQWHETVLAGGYGDHFEESLMKALCRPYLWQEMMNASQRQQVRQFLLDTALQRMDNERGFNNVLCWLAVFNTLGGAA
PLIRSLWSRWWALDTPGKAVCAIQYAAHLIYPIEANPLWSQEWIGWGHPLGHKDGWSSDNRAFLRQMLTPEMIVAGVQAA
AEILRGEPEGAMAARIAQDAYEAMDILTIQIEDLLRDLSCDESGHALE
>SEQF1516_EDU88184.1 glutaredoxin 3 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MANVEIYTKETCPYCHRAKALLSSKGVSFQELPIDGNAAKREEMIKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDP
LLK
>SEQF1516_EDU88185.1 hypothetical protein ECH7EC4501_0924 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITVNLEKIPVNICPDSSHIGGTPEKTVYTRVYTIKIVITEIPVMTSP
>SEQF1516_EDU88186.1 acyltransferase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQPKIYWIDNLRGIACLMVVMIHTTTWYVTNAHSVSPVTWDIANVLNSASRVSVPLFFMISGYLFFGERSAQPRHFLRIG
LCLFFYSAIALLYIALFTSINVELALKNLLQKPVFYHLWFFFAIAVIYLVSPLIQVKNVGGKMLLVLMVVIGIIANPNTV
PQKIDGFEWLPINLYINGDTFYYILYGMLGRALGMMDTQHKALSWVSAALFATGVFIISRGTLYELQWRGNFADTWYPYC
GPMVFICAIALLTLVKNTLDTRTIRGLGLISRHSLGIYGFHALIIHALRTRGIELKNWPILDIIWIFCATLAASLLLSML
VQRIDRNRLVS
>SEQF1516_EDU88187.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQQEEHNNKIDLLEKQQAQLKSQLETIQKQQTGIISSTKTLTHVIKSVKDQQNTFIFTEFNPAKTKYFILNNGSVALAG
RVLSIDATENGSVIHISLVNLLSTPISNIGFNATWGGEKPVDAKEFARWQQLLFNTSMKSTLKLLPGQWQDINLTLKGVS
PNNLGYLKLAINMENIQFDNLPSAENRQKRSKK
>SEQF1516_EDU88188.1 type III secretion apparatus H+-transporting two-sector ATPase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISEHDSVLEKYPRIQKVLNSTVPALSLNSSTRYEGKIINIGGTIIKARLPKARIGAFYKIEPSQRLAEVIAIDEDEVFL
LPFEHVSGMYCGQWLSYQGDEFKIRVGDALLGRLVDGIGRPMESNIAAPYLPFERSLYAEPPDPLLRQVIDQPFILGVRA
IDGLLTCGIGQRIGIFAGSGVGKSTLLGMICNGASADIIVLALIGERGREVNEFLALLPQSTLSKCVLVVTTSDRPALER
MKAAFTATTIAEYFRDQGKNVLLMMDSVTRYARAARDVGLASGEPDVRGGFPPSVFSSLPKLLERAGPAPKGSITAIYTV
LLESDNVNDPIGDEVRSILDGHIVLTRELAEENHFPAIDIGLSASRVMHNVVTSEHLRAAAECKKLIATYKNVELLIRIG
EYTMGQDPEADKAIKNRKLIQNFIQQSTKDISSYEKTIESLFKVVA
>SEQF1516_EDU88189.1 putative fructoselysine transporter FrlA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGSQELQRKLGFWAVLAIAVGTTVGSGIFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYL
KNAGSRPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHLRSVEGGAAFQTLITIAK
IIPFTIVIGLGIFWFKAENFAAPATTAIGATGSFMALLAGISATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVL
VLYTLLALVISGLMPFDKLANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFFKCF
GHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWCRKRDDYKPLWRTPAFGLMTPLAIAS
SLILVASTFVWAPIPGLICAVIVIATGLPAYAFWAKRSRQLNALS
>SEQF1516_EDU88190.1 O-methyltransferase, family 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYEQDSLSALDAITEAQRIAFAPMLFQTALCLRNAGVLSYLDRQGKHGATLADITEHSHINEYATSVLLDMGLSGRIITC
KEGIYYLAKIGHYLLHDTMTRVNMDFTQDVCYQGLFFLADSLNEGKPSGLKVFGDWSTIYPALSQLPDAARESWFAFDHY
YSDGAFNAALPYVFANNPTTLYDVGGNTGKWALRCCKYNENIAVTLLDLPQQIVLAKENIANAGFSDRIDFHAVDMLSDA
PLPGEADIWWMSQFLDCFSPEQIISILSKIASVMKPGAKVCIMELFWDAQRFEAASFSLNASSLYFTCMANGNSRFYSAE
KFYDYLNKAGFQVAERHDNLGVGHTLLICQKK
>SEQF1516_EDU88191.1 multidrug resistance protein MdtE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNRRRKLLIPLLFCGAMLTACDDKSAENTAAMTPEVGVVTLSPGSVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEG
DKVNQGDSLYQIDPAPLQAELNSAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAV
EQATINLQYANVTSPITGVSGKSSVTVGALVTANQADSLVTVQRLDPIYVDLTQSVQDFLRMKEEVASGQIKQVQGSTPV
QLNLENGKRYSQTGTLKFSDPTVDETTGSVTLRAIFPNPNGDLLPGMYVTALVDEGSRQNVLLVPQEGVTHNAQGKATAL
ILDKDDVVKLREIEASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ
>SEQF1516_EDU88192.1 putative adhesin [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKIFKVIWNPATGNYTVTSETAKSRGKKSGRSKLLISALVAGGMLSSFGALANAGNDNGQGVDYGSGSAGDGWVAIGKG
AKANTFMNTSGSSTAVGYDAIAEGQYSSAIGSKTHAIGGASMAFGVSAISEGDRSIALGASSYSLGQYSMALGRYSKALG
KLSIAMGDSSKAEGANAIALGNATKATEIMSIALGDTANASKAYSMALGASSVASEENAIAIGAETEAAENATAIGNNAK
AKGTNSMAMGFGSLADKVNTIALGNGSQALADNAIAIGQGNKADGVDAIALGNGSQSRGLNTIALGTASNATGDKSLALG
SNSSANGINSVALGADSIADLDNTVSVGNSSLKRKIVNVKNGAIKSDSYDAINGSQLYAISDSVAKRLGGGAAVDVDDGT
VTAPTYNLKNGSKNNVGAALAVLDENTLQWDQTKGKYSAAHGTSSPTASVITDVADGTISASSKDAVNGSQLKATNDDVE
ANTANIATNTSNIATNTANIATNTTNITNLTDSVGDLQADALLWNETKKAFSAAHGQDTTSKITNVKDADLTADSTDAVN
GSQLKTTNDAVATNTTNIANNTSNIATNTTNISNLTETVTNLGEDALKWDKDNGVFTAAHGTETTSKITNVKDGDLTTGS
TDAVNGSQLKTTNDAVATNTTNIATNTTNISNLTETVTNLGEDALKWDKDNGVFTAAHGNNTASKITNILDGTVTATSSD
AINGSQLYDLSSNIATYFGGNASVNTDGVFTGPTYKIGETNYYNVGDALAAINSSFSTSLGDALLWDATAGKFSAKHGTN
GDASVITDVADGEISDSSSDAVNGSQLHGVSSYVVDALGGGAEVNADGTITAPTYTIANADYDNVGDALNAIDTTLDDAL
LWDADAGENGAFSAAHGKDKTASVITNVANGAISAASSDAINGSQLYTTNKYIADALGGDAEVNADGTITAPTYTIANAE
YNNVGDALDALDDNALLWDETANGGAGAYNASHDGKASIITNVANGSISEDSTDAVNGSQLNATNMMIEQNTQIINQLAG
NTDATYIQENGAGINYVRTNDDGLAFNDASAQGVGATAIGYNSVAKGDSSVAIGQGSYSDVDTGIALGSSSVSSRVIAKG
SRDTSITENGVVIGYDTTDGELLGALSIGDDGKYRQIINVADGSEAHDAVTVRQLQNAIGAVATTPTKYFHANSTEEDSL
AVGTDSLAMGAKTIVNGDKGIGIGYGAYVDANALNGIAIGSNAQVIHVNSIAIGNGSTTTRGAQTNYTAYNMDAPQNSVG
EFSVGSADGQRQITNVAAGSADTDAVNVGQLKVTDAQVSQNTQSITNLDNRVTNLDSRVTNIENGIGDIVTTGSTKYFKT
NTDGVDASAQGKDSVAIGSGSIAAADNSVALGTGSVATEENTISVGSSTNQRRITNVAAGKNATDAVNVAQLKSSEAGGV
RYDTKADGSIDYSNITLGGGNGGTTRISNVSAGVNNNDVVNYAQLKQSVQETKQYTDQRMVEMDNKLSKTESKLSGGIAS
AMAMTGLPQAYTPGASMASIGGGTYNGESAVALGVSMVSANGRWVYKLQGSTNSQGEYSAALGAGIQW
>SEQF1516_EDU88193.1 HAD hydrolase, IA family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQIEAVFFDCDGTLVDSEVICSRAYVTMFREFGIHVDLKEIFTRFKGVKLYEIIDIISKEQGVTMVQADAEHVYRAEVA
RLFDTELEDIAGANELLASINVPMCVVSNGPVSKMQHSLGKLNMLHYFPEKLFSGYDIQRWKPDPALMFHAAKAMNVNVE
NCILVDDSSAGAQSGIDAGMEVFYFCADPHNKPIVHPKVTTFTELSQLPALWKARGWNITR
>SEQF1516_EDU88194.1 conserved domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNKFTGVLLLGTALLAGCVDREGYYNSVREEESHGLTSLRGQPALRYSDDWSRWPRVYGATALYPLYASAYYKLVPEPKD
KDRTSLAWQAYGLQQTRTAEAYDSLIKGSATVIFVAQPSEGQKKRAEEAGVKLKYTAFAREAFVFIVDINNPVNSLSEHQ
VKDIFSGKTSRWNKVGGSDEHIKVWQRPEDSGSQTIMKGLVMQDTPMLPAKKSTVIDLMGGLITEVADYQNTPSSIGYTF
HYYVTRMNDNMLKMRKQIKLLAINGVAPTEENIRNGTYPYIVDAYMVTRENPTPETQKFVDWFISQQGQQLVEDVGYVPL
YEASPESSGQ
>SEQF1516_EDU88195.1 cellulase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVLRSGLVTMLLLAAFSVQAACTWPAWEQFKKDYISQEGRVIDPSDARKITTSEGQSYGMFFALAANDRAAFDNILDWT
QNNLAQGSLKERLPAWLWGKKENSKWEVLDSNSASDGDVWMAWSLLEAGRLWKEQRYTDIGSALLKRIAREEVVTVPGLG
SMLLPGKVGFAEDNSWRFNPSYLPPTLAQYFTRFGAPWTTLRETNQRLLLETAPKGFSPDWVRYEKDKGWQLKAEKTLIS
SYDAIRVYMWVGMMPDSDPQKARMLNRFKPMATFTEKNGYPPEKVDVATGKAQGKGPVGFSAAMLPFLQNRDAQAVQRQR
VADNFPGSDAYYNYVLTLFGQGWDQHRFRFSTKGELLPDWGQECANSH
>SEQF1516_EDU88196.1 hypothetical protein ECH7EC4501_0921 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTIQGAPSFVSWHNYQAITFFMIDWQAVFLHRSFLMAAVFLCALCRH
>SEQF1516_EDU88197.1 GntR-family transcriptional regulator FrlR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSATDRYSHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQYNVSRITIRKAISDLVADGVLIRWQGKGTFVQSQKV
ENALLTVSGFTDFGVSQGKATKEKVIEQERISAAPFCEKLNIPGNSEVFHLCRVMYLDKEPLFIDSSWIPLSRYPDFDEI
YVEGSSTYQLFQERFDTRVVSDKKTIDIFAATRPQAKWLKCELGEPLFRISKIAFDQNDKPVHVSELFCRANRITLTIDN
KRH
>SEQF1516_EDU88198.1 amino acid/peptide transporter [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNTTTPMGMLQQPRPFFMIFFVELWERFGYYGVQGVLAVFFVKQLGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGT
KRTIVLGALVLAIGYFMTGMSLLKPDLIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGTFTLFYMSINIGSLIAL
SLAPVIADKFGYSVTYNLCGAGLIIALLVYIACRGMVKDIGSEPDFRPMSFSKLLYVLLGSVVMIFVCAWLMHNVEVANL
VLIVLSIVVTIIFFRQAFKLDKTGRNKMFVAFVLMLEAVVFYILYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPF
WVVLASPILAGIYTHLGNKGKDLSMPMKFTLGMFMCSLGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLGELFISALG
LAMIAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPDNITDPLETLPVYTNVFGKIGLVTLGVAVVMLLMVPWLK
RMIATPESH
>SEQF1516_EDU88199.1 hypothetical protein ECH7EC4501_0715 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMTTLLPVFTKPSPLALNALRAGRICRFLLIPDGRIR
>SEQF1516_EDU88200.1 fructose-bisphosphate aldolase, class II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPLVNGRILLDRIQEKRVLAGAFNTTNLETTISILNAIERSGLPNFIQIAPTNAQLSGYDYIYEIVKRHADKMDVPVSLH
LDHGKTQEDVKQAVRAGFTSVMIDGAAFSFEENIAFTQEAVDFCKSYGVPVEAELGAILGKEDDHVSEADCKTEPEKVKT
FVERTGCDMLAVSIGNVHGLDDIPRIDIPLLKRIAEVCPVPLVIHGGSGIAPEILRSFVNYRVAKVNIASDLRKAFITAV
GKAYVNNHNEANLARVMASAKNAVEEDVYSKILMMNEGHRLVRKAS
>SEQF1516_EDU88201.1 pantetheine-phosphate adenylyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGNVEVVGFSDLMANFARN
QHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA
>SEQF1516_EDU88202.1 transporter, solute:sodium symporter (SSS) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSLQILSFVGFTLLVAIITWWKVRKTDTGSQQGYFLAGRSLKAPVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEV
TSAVTLIFLALIFLPRYLKRGIATIPDFLEERYDKTTRMIIDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQISHG
AAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMVPVFGLIAMGKGSFMQGIEQITTVHAEKLNSVGGPTD
PLPIGAAFTGLILVNTFYWCTNQGIVQRTLASKSLAEGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTL
VNNVLPVPLVGFFGAVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFGFFIAIVSVLVAPWIANAP
QGLYSWMKQLNGIYNVPLVTIIIMGFFFLRIPALAAKVAMGIGIISYITINYLVKFDFHFLYVLACTFCINVVVMLVIGF
IKPRATPFTFKDAFAVDMKPWKNVKIASIGILFAMIGVYAGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSWRHRHDPA
VTFTPDAKDSL
>SEQF1516_EDU88203.1 hypothetical protein ECH7EC4501_1011 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVELVCFNDDDCAQVRELLKQSNGNITDDKIDEITACLSNPQGITCFYYSPLQGYQSFLKNTSQDVSELLSKSLNGTISS
TSGLKKSGNAFFGTGKYLKEIDFTINGFSQKMYLMAVNNVGNEVKLQCSCYFTTGSVDEEKSKSDKIDFTFSGAATTADL
>SEQF1516_EDU88204.1 ATP synthase F0, C subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPDLIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA
>SEQF1516_EDU88205.1 glycosyl transferase, family 2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVNFSPCVLIPCYNHGAMMPGVLARLKPFNLPCIVVDDGSDATTQQQLDSLLAEQPGVTLIRLAENAGKGAAVMRGLQA
AADAGFSHAVQVDADGQHAIEDIPKLLALAEQQPAALISGQPIYDDSIPRSRLYGRWVTHVWVWIETLSLQLKDSMCGFR
VYPVAPTLQLAKHATIGKRMDFDTEVMVRLYWQGNTSYFVPTRVTYPLDGLSHFDALKDNVRISLMHTRLFFGMLPRIPS
LLMRRSSCHWARQSEVKGLWGMRLMLLVWRLLGRTAFSALLYPVVGVYWLTASRARKASQDWLARVRQHQPQAAKLNSYQ
HFLRFGNAMLDKIASWRGELQPGRDVLFAPGAEAALDVRDPRGKLLLASHLGDVEVCRALAKIQGYKTINALVFSENAQR
FKQIMQEMAPQAGINLMPVTDIGPETAILLKEKLDNGEWVAIVGDRIAVNPQRGGDWRVCWSSFMGQPAPFPQGPFILAS
ILRCPVNLIFALRQHGKLHIHCESFADPLQLPRGERQQALQNAIDHYAARLEHYALQSPLDWFNFFDFWQLPEIQDKE
>SEQF1516_EDU88206.1 protein hokA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGSYELAAFLACNLKE
>SEQF1516_EDU88207.1 auxiliary transport protein, membrane fusion protein (MFP) family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLILLMNYNHPYTFTAQKAVIAIPITPQVTGIVTEVTDK
NNQLIQKGEVLFKLDPVRYQARVDRLQADLMTATHNIKTLRAQLTEAQANTTQVSAERDRLFKNYQRYLKGSQAAVNPFS
ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMVNGEQSQIVSLRAQLTEAKYNLEQTVIRAPSNGYVTQVLIRPGTY
AAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLKPGDDAEVVFNALPGQVFHGKLTSILPVVPGGSYQAQGVLQSLTVVPG
TDGVLGTIELDPNDDIDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH
>SEQF1516_EDU88208.1 hypothetical protein ECH7EC4501_0997 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRPPPVDDVLSVSFFYPFINDYRTIAVRSLQFKKQNAIDKNKKE
>SEQF1516_EDU88209.1 nickel ABC transporter, ATP-binding protein NikE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLLNVSDLSHHYAHGGFSGKHQHQAVLNNVSLTLKSGETVALLGRSGCGKSTLSRLLVGLESPSQGNISWRGESLAKLN
RAQRKAFRRDIQMVFQDSISAVNPRKTVREILREPMRHLLSLKKSEQLARASEMLHAVDLDDSVLDKRPPQLSGGQLQRV
CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQAVGEKL
TFSSDAGRVLQNAILPAFPVRRRATEKV
>SEQF1516_EDU88210.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGLFDEVVGAFLKGDAGKYQAILSWVEEQGGIQVLLEKLQSGGLGAILSTWLSNQQGNQPVSGEQLESALGTNAVSDLGQ
KLGVDTSTASCLLAEQLPKIIDALSPQGEVSPQANNDLLSAGMELLKGKLFR
>SEQF1516_EDU88211.1 xylulokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYIGIDLGTSGVKVILLNEQGEVVASQTEKLTVSRPHPLWSEQDPEQWWQATDRAMKALGDQHSLQDVKALGIAGQMHGA
TLLDAQQRVLRPAILWNDGRCAQECALLEARVPLSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
TGEFASDMSDAAGTMWLDVAKRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAKAWGMATVPVVAGGGDNAAGAVG
VGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHSFCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALIAAAQQA
DESAEPVWFLPYLSGERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTLIGGGARSE
YWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLPLEQSHLPDAQRYAAYQPRRETFRRLYQQLL
PLMA
>SEQF1516_EDU88212.1 putative valine--pyruvate aminotransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIPEMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELL
TLLAGMLREKLGWDIEAQNIALTNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELL
PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVIDNAYGVPFPGIIFSEARPLWNPN
IVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGIISLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAI
IRRYLPEDRCLIHKPEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYVPEPEKIEA
GVKILAEEIERAWAESH
>SEQF1516_EDU88213.1 PerC protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPEQLVTFGDVKKAADRTLKEMGINPQDEWKNYSFSDAGDDLALS
>SEQF1516_EDU88214.1 SepQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPLSSQLNMKINDFYLPLLPVIGTGRLYITSKGHACHAYFREVSGHGIRFTLTYSGYEGRFWISEEQFIQWCQELFPYS
ESRLIPEDTIKLMILWVMQTALPEGDVSVDDVQFTMLNKDIYPVIENNNGENRLNVIILETTVQSLQYLINDNWQLVPHS
NALFFDGYIVPGWTDYPVTELRVGDSLRLYHVDDSQERRCWIVINTPLATVNLSDNNLSVTDVLAADLLSALSNETVMNR
IYCAIGTVHIDIHMLRNVKKDDIINSDGYHLFGGCQLIRNNTTIAYGSIVKINEDFYFTVSIVCD
>SEQF1516_EDU88215.1 alcohol dehydrogenase II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASSTFFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDSMLTKLGMAGDVQKALEERNIFSVIYDGTQPNPTTENVAAG
LKLLKENNCDSVISLGGGSPHDCAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
MAIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALKAVTMIAENLPLAVEDGSNAKAR
EAMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYNLPHGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGA
EACINAIRELAKKVDIPAGLRDLNVKEEDFAVLAANALKDACGFTNPIQATHEEIVAIYRAAM
>SEQF1516_EDU88216.1 transcriptional regulatory protein UhpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW
>SEQF1516_EDU88217.1 phosphate transport system regulatory protein PhoU [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMHNQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQ
PTASDLRLVMVISKTIAELERIGDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVKGQDFRHVGGDELDKLLAGKDPK
E
>SEQF1516_EDU88218.1 phosphoribulokinase/uridine kinase family protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSFHRYTRPEMDMAIRKARDAGRHISYFGPEANDFGLLE
QTFIEYGQSGKGKSRKYLHTYDEAVPWNQVPGTFTPWQPLPEPTDVLFYEGLHGGVVTPQHNVAQHVDLLVGVVPIVNLE
WIQKLIRDTSERGHSREAVMDSVVRSMEDYINYITPQFSRTHLNFQRVPTVDTSNPFAAKGIPSLDESFVVIHFRNLEGI
DFPWLLAMLQGSFISHINTLVVPGGKMGLAIELIMLPLVQRLMEGKKIE
>SEQF1516_EDU88219.1 small heat shock protein IbpA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDENHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQ
KERTYLYQGIAERNFERKFQLAENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN
>SEQF1516_EDU88220.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLINIGRLLMLCVWGFLILNLVHPFPRPLNIFVNVALIFTVLMHGMQLALLKSTLPKDGPQMTTAEKVRIFLFGVFELLV
WQKKFKVKK
>SEQF1516_EDU88221.1 long polar fimbria protein A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKVVFALTALALTSGTVFAAESGDGTVKFTGEIVDSPCVLSVDSQNQEVVLGQVQKSVFAAVGDKSPAKPFEIKLEDCD
TTTMKKANVSFSGVGDADKSDLISVSTEAGAAKGVGIGIYDNSNTLVALNGGKASVDLSKGQTVLYFTANYVSTLATVTT
GYGNAQVDFNLSYE
>SEQF1516_EDU88222.1 transcriptional regulatory protein OmpR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLLTRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPII
MVTAKGEEVDRIVGLEIGADDYIPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMP
LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAHPRYIQTVWGLGYVFVPDGSKA
>SEQF1516_EDU88223.1 cytoplasmic trehalase TreF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMIEGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPD
CAPKMDPLDILIRYRKVRRHRDFDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQ
SYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYYLSRSQPPVFALMVELFEEDGVR
GARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMPDGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAG
AASGWDYSSRWLRDTGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRYLWDDENGI
YRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGILASEYETGEQWDKPNGWAPLQWMAIQGFKMY
GDDLLGDEIARSWLKTVNQFYLEQHKLIEKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP
>SEQF1516_EDU88224.1 M23 peptidase domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRGKAINTMTRAVKPRRFAIRPIIYASVLSAGVLLCAFSAHADERDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQE
EAISEATRKLRETQNTLNQLNKQIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYF
GYLNQARQETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALNERKKTLAGLESSIQQGQQQLSELRAN
ESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEATRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGE
QLQGELRWKGMVIGASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQPIALVGSS
GGQGRPSLYFEIRRQGQAVNPQPWLGR
>SEQF1516_EDU88225.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKILRAYILCRNTPERQVLGYYTLCGSCFERAALPSKSKQ
KKIPYKNIPSVTLGRLAIDRSLQGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNEKAHTFYKSLGFIPLVGENENAL
FFPTKSIELLFTQSD
>SEQF1516_EDU88226.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTLPDTHVREASRCPSPITIWQTLLGRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYVLVRTDQPGF
SACTRSQLINSIDILRARRATGLMTRDNYRTVNNITLGKHPEAK
>SEQF1516_EDU88227.1 UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAANELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQL
GTGHAMQQAAPFFADDEDILMLYGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATD
EQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQRLSEVEGVNNRLQLSRLERVYQ
SEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDTNVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANL
AAACTIGPFARLRPGAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDD
VFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWRRPVKKK
>SEQF1516_EDU88228.1 hemin import ATP-binding protein HmuV [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MISAQNLVYSLQGRRLTDNVSLTFPGGEIVAILGPNGAGKSTLLRQLTGYLQPDSGECRLFNKPLNEWSITELAKHRAVM
RQNSHMAFPFSVQEVIQMGRHPHRTGNQDNETAQIMALCDCQALANRDYRQLSGGEQQRVQLARLLVQLWEPTPSPKWLF
LDEPTSALDIHHQQHLFRLLRQLVHERQFNVCCILHDLNLAAHYADRVVLMQKGKVIANGKPQDVLTQQALTMLYGADIT
VLKDPANHSPLIVLDH
>SEQF1516_EDU88229.1 ferrous iron transport protein B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHY
ILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALARLRNEMDDP
ALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVH
GIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVG
FGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYMLGIVMAVLTGLMLKYTIMRG
EATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKP
IGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEAS
KGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQH
PTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH
>SEQF1516_EDU88230.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCDFSDMTVDEAAKSAMQAELICSLMMGNTGGMTEGEIESLLALIKQLTGKAGSWLIAASGDDAICVND
>SEQF1516_EDU88231.1 high-affinity branched-chain amino acid ABC transporter, ATP-binding protein LivG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQPLLSVNGLMMRFGGLLAVNNVNLELYPQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRDQHLEGLPGQQIARM
GVVRTFQHVRLFREMTVIENLLVAQHQQLKTGLFSGLLKTPSFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQR
RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVMGISDRIYVVNQGTPLANGTPEQ
IRNNPDVIRAYLGEA
>SEQF1516_EDU88232.1 starch synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAFPDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIY
LIDAPHLYDRPGSPYHDTNLFAYTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTV
HNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYAREITEPQFAYGMEGLLQQRHREGR
LSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAENKRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQ
GGQLALLGAGDPVLQEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTLPLVRRTGG
LADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRFVQRQAMAMDFSWQVAAKSYRELYYRLK
>SEQF1516_EDU88233.1 acetyltransferase, GNAT family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLTIIRLEKFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARFNERLLAAVRVTLSGTEGALDSLRVREVTRRRGVGQY
LLEEVLRNNPGVSCWWMADAGVEDRGVMTAFMQALGFTAQQGGWEKR
>SEQF1516_EDU88234.1 aerobic C4-dicarboxylate transport protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKLIKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLY
FEIVSTIALIIGLIIVNVVQPGAGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLF
GFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQLGQLIICFYITCILFVVLVLGS
IAKATGFSIFKFIRYIREELLIVLGTSSSESALPRMLDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQAT
NSQMDIVHQITLLIVLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNGVATIVVAK
WVKELDHKKLDDALNNRAPDGKTHELSS
>SEQF1516_EDU88235.1 lipopolysaccharide core biosynthesis glycosyltransferase RfaQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDKPFRRILLIKMRFHGDMLLTTPVISSLKKNYPDAKIDVLLYQDTIPILSENPEINALYGIKNKKAKASEKIANFFHLI
KVLRANKYDLIVNLTDQWMVAILVRLLNARVKISQDYHHRQSAFWRKSFTHLVPLQGGNVVESNLSVLTPLGLDSLVKQT
TMSYPPASWKRMRRELDHAGVGQNYVVIQPTARQIFKCWDNAKFSAVIDALHARGYEVVLTSGPDKDDLACVNEIAQGCQ
TPPVTALAGKVTFPELGALIDHAQLFIGVDSAPAHIAAAVNTPLISLFGATDHIFWRPWSNNMIQFWAGDYREMPTRDQR
DRNEMYLSVIPAADVIAAVDKLLPSSTTGTSL
>SEQF1516_EDU88236.1 high-affinity branched-chain amino acid ABC transporter, periplasmic Leu/Ile/Val-binding protein LivJ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIKGKALLAGCIALAFSNMALAEDIKVAVVGAMSGPVAQYGDQEFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQ
AVAVANKVVNDGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGLDSDQGPTAAKYILEKVK
PQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEKDFSTLVARLKKENIDFVYYGGYHPEMGQILRQARAAG
LKTQFMGPEGVANVSLSNIAGESAEGLLVTKPKNYDQVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQSDDP
AEIAKYLKANSVDTVMGPLTWDEKGDLKGFEFGVFDWHANGTATDAK
>SEQF1516_EDU88237.1 lipid A-core, surface polymer ligase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTSTLFFSLEKKNWIAYWNRALVFLFITTYFLGGITRYKHLIVILMTITTIVYLCKRPKHYLSLFKTFLFGSVAILTIAA
LLSLLQSPDAGASMKEIFKAIIENTLLCTIAIPIILRDEKREDVEKIVFFSFISALGLRCFSELITYYKDYQQGIMPFAD
YRHRSISDSMVFLFPALLNLWLIKSAKYRISFVVLSVIFIFLILGTLSRGAWLSVLVIGLIWILMFKQWKLLLVGVMVAI
IALSVIFTHKEMTAKLTYKLQQTNSSYRYANGTQGSALDLILENPVIGYGYGNVAYKDVYNKRVIDYPEWTFRQSIGPHN
FALFIWFGTGLLGLVSLMMLYCAILKECIKNGVKNKYRSPYNAYYIILLSFIGYFVIRGNVEQIEPNLLGVYAGLLLAMK
NK
>SEQF1516_EDU88238.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNVFSQTQRYKALFWLSLFHLLVITSSNYLVQLPVSIFGFHTTWGAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPAL
LISYVISSLFYMGSWQGFGALAHFNLFVARIATASFMAYALGQILDVHVFNRLRQSRRWWLAPTASTLFGNVSDTLAFFF
IAFWRSPDAFMAEHWMEIALVDYCFKVLISIVFFLPMYGVLLNMLLKRLADKSEINALQAS
>SEQF1516_EDU88239.1 NAD-dependent glycerol-3-phosphate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATLERDRCNAAFLPDVPFPDTLHLESDLATALAASRNIL
VVVPSHVFGEVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
QTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLAEMSRLGAALGADPATF
MGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSAQEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNA
REAALTLLGRARKDERSSH
>SEQF1516_EDU88240.1 hypothetical protein ECH7EC4501_0852 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIIVLLTLNFIFLSSLQILTEFISMIFFILIFYFIYCFNAISGKLEWI
>SEQF1516_EDU88241.1 AntA/AntB antirepressor domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRPNMPVQGQGFVQSEELSQQYFAAIIPVSPGIIGGYETGIVSARALHKALGVGRDFTTWIKGRIEEYGFKKGVDFEVV
ENLYFDSPKRGSQSVNIEQFDSGWTTKRGGDRRSEDYLISTNMAKELAMVERTEQGRAIRQYFIKCEEELHKAAPERAAA
LRRELKARVTVASFFKPMCAARELYRAELGKETHQHHYTTESNMLARIVLGGMTAKQWAQANGIKGKPRDSMSVMQLEHL
SYLDQSNITLIELGMTYQQRKAELIRLSQRWLARRMGEHEHA
>SEQF1516_EDU88242.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIIKKSGGRWQLSLLASVVISAFFLNTAYAWQQEYIVDTQPGHSTERYTWDSDHQPDYNDILSQRIQSSQRALGLEVNLA
EETPVDVTSSMSMGWNFPLYEQVTTGPVAALHYDGTTTSMYNEFGDSTTTLTDPLWHASVSTLGWRVDSRLGDLRPWAQI
SYNQQFGENIWKAQSGLSRMTATNQNGNWLDVTVGADMLLNQNIAAYAALSQAENTTNNSDYLYTMGVSARF
>SEQF1516_EDU88243.1 penicillin-binding protein 1A [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRLQIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVK
AFIATEDSRFYEHHGVDPVGIFRAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL
ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRMLDEGYITQQQF
DQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRYGESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPA
NVLWKVGESAWDNNKITDTLKALPTYGPLLPAAVTSANPQEATAMLADGSTVALSMEGVRWARPYRSDTQQGPTPRKVTD
VLQTGQQIWVRQVGDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQSKFNRATQALRQVGSNIKPFLYTAAMDKGL
TLASMLNDVPISRWDAGAGSDWQPKNSPPQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTES
LALGSASFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDTQKSNVLENNDVEDVAI
SREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFLIKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTT
NSSKDAWFSGYGPGVVTSVWIGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPGIV
TVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF
>SEQF1516_EDU88244.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MHYAVVVMLELLCCIHAYRTGQERYWIFIIFCFPVIGCVAYFVIVMLPETGADRHGHTLLMRLQDKLNPERHLRKLTEEL
AIAETNQNHYALANELARLGRYHEAVPHYQQALSGIFAHEAAMMLSLAQAQFAIQEFAACQQTLEDVMRYNPDFQSADGH
LLFARTLAAQEKYADAESEFEVLISYYPGPQARIYYAEMLAKMSRLREANEQYVAVVDTAKRSRPHYRKHHREWIKTANE
RLKQSVVQ
>SEQF1516_EDU88245.1 protein transporter HofQ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGL
ITRQEGNILSVHSIAWQNDNIARQEAEQARAQANLPLENRNITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
KTALSALEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTTLGSDLSVATATTHVGFNIGRIN
GRLLDLELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKL
HISQNVPGQVLQQADGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERREL
VVFITPRLVSSE
>SEQF1516_EDU88246.1 IS66 family element, orf2 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVFIFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPS
ARDGKVFLTQAQLAMLLEGIDWRQPKRLLTSLTML
>SEQF1516_EDU88247.1 aspartate-semialdehyde dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAAPSFGGTTGTLQDAFDLEALKALDIIVTCQGGDYTNE
IYPKLRESGWQGYWIDAASSLRMKDDAIIILDPVNQDVITDGLNNGIRTFVGGNCTVSLMLMSLGGLFANDLVDWVSVAT
YQAASGGGARHMRELLTQMGHLYGHVADELATPSSAILDIERKVTTLTRSGELPVDNFGVPLAGSLIPWIDKQLDNGQSR
EEWKGQAETNKILNTSSVIPVDGLCVRVGALRCHSQAFTIKLKKDVSIPTVEELLAAHNPWAKVVPNDREITMRELTPAA
VTGTLTTPVGRLRKLNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA
>SEQF1516_EDU88248.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMNIIRLYIYPLFLGFVIVPLLVWPTVVALAACVITLSFLGEILFSIPLMHRRISLLQLQLWLSAEYALFFCAMVGVGWQ
FARRTPPELKSRLHCWLVFAPVYFWLLLWNIIFYVAPAQIALLENMRSFFLTVVWLPLNFSPFWSQQWIDFVGPISAQLG
FALGYYCQWRSKNRSQIRKWSEWGTCLSFVTLGMMAWALR
>SEQF1516_EDU88249.1 cell division protein FtsY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQTVVEEIVQAQEPVKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAE
NEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELEAQAL
AAEAAEEAVMVVPPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRGKKIDDDLFEELEEQLLIAD
VGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTIGKLARQFEQ
QGKSVMLAAGDTFRAAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLMEELKK
IVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTAKGGVIFSVADQFGIPIRYIGVGERIED
LRPFKADDFIEALFARED
>SEQF1516_EDU88250.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPWLLFGAGGKGVGARTLELALAEQRPVVAVIRHADAATKLAQQGVQVFTGDACDASVVAAACRAAGPDALIISTMGGA
QDYLAHRTVIDEAEKAGISRMILVTSLGCGDSWPFLSERAKAAFGQAVREKTLAESWLQTSQLDYAILRPGGLLDGAATG
KAQRIQNQECHGFVRRADVAAHIHELANAPALNQQVYSLIEPDLKPA
>SEQF1516_EDU88251.1 tryptophanyl-tRNA synthetase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQHAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIF
VQSHVPEHAQLGWALNCYTYFGELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDI
AQRFNALYGDIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVKKIKRAVTDSDEPPVVRYDVQNK
AGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGEVADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRT
LKAVYEAIGFVAKP
>SEQF1516_EDU88252.1 alpha-amylase, periplasmic [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLAACFLTLLPGFAVAASWTSPGFPAFSEQGTGTFVSHAQLPKGTRPLTLNFDQQCWQPADAIKLNQMLSLQPCSNTPP
QWRLFRDGKYTLQIDTRSGTPTLMISIQNAAEPVANLVRECPKWDGLPLTLDVSATFPEGAAVRDYYSQQIAIVKNGQIT
LQPAATSNGLLLLERAETDASAPFDWHNATVYFVLTDRFENGDPSNDQSYGRHKDGMAEIGTFHGGDLRGLTNKLDYLQQ
LGVNALWISAPFEQIHGWVGGGTKGDFPHYAYHGYYTQDWTNLDANMGNEADLRTLVDSAHQRGIRILFDVVMNHTGYAT
LADMQEYQFGALYLSGDEVKKTLGERWSDWKPAAGQTWHSFNDYINFSDKTGWDKWWGKNWIRTDIGDYDNPGFDDLTMS
LAFLPDIKTESTTASGLPVFYKNKTDTHAKAIDGFTPRDYLTHWLSQWVRDYGIDGFRVDTAKHVELPAWQQLKTEASAA
LREWKKANPDKALDDKPFWMTGEAWGHGVMQSDYYRHGFDAMINFDYQEQAAKAVDCIAQMDTTWQQMAEKLQGFNVLSY
LSSHDTRLFREGGDKAAELLLLAPGAVQIFYGDESSRPFGPTGSDPLQGTRSDMNWQDVSGKSAANVAHWQKISQFRARH
PAIGAGKQTTLSLKQGYGFVREHGDDKVLVIWAGQQ
>SEQF1516_EDU88253.1 intimin type gamma [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITHGCYTRTRHKHKLKKTLIMLSAGLGLFFYVNQNSFANGENYFKLGSDSKLLTHDSYQNRLFYTLKTGETVADLSKSQ
DINLSTIWSLNKHLYSSESEMMKAAPGQQIILPLKKLPFEYSALPLLGSAPLVAAGGVAGHTNKLTKMSPDVTKSNMTDD
KALNYAAQQAASLGSQLQSRSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKM
LAFGQVGARYIDSRFTANLGAGQRFFLPANMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKK
DYDERPANGFDIRFNGYLPSYPALGAKLIYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNEND
LLYSMQFRYQFDKSWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTEHSTQKIQLIVKSKY
GLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNIYKVTARAYDRNGNSSNNVQLTITVLSNGQVVDQVGV
TDFTADKTSAKADNADTITYTATVKKNGVAQANVPVSFNIVSGTATLGANSAKTDANGKATVTLKSSTPGQVVVSAKTAE
MTSALNASAVIFFDQTKASITEIKADKTTAVANGKDAIKYTVKVMKNGQPVNNQSVTFSTNFGMFNGKSQTQATTGNDGR
ATITLTSSSAGKATVSATVSDGAEVKATEVTFFDELKIDNKVDIIGNNVRGELPNIWLQYGQFKLKASGGDGTYSWYSEN
TSIATVDASGKVTLNGKGSVVIKATSGDKQTVSYTIKAPSYMIKVDKQAYYADAMSICKNLLPSTQTVLSDIYDSWGAAN
KYSHYSSMNSITAWIKQTSSEQRSGVSSTYNLITQNPLPGVNVNTPNVYAVCVE
>SEQF1516_EDU88254.1 hypothetical protein ECH7EC4501_0717 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDSVSRLFSCRNRAFLITFYQQSQPDSNINIHVVYGSEL
>SEQF1516_EDU88255.1 putative lipoprotein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLNFKGFFKAASLFPLALMLSGCISYALVSHTAKGSSGKYQSQSDTITGLSQAKDSNGTKGYVFVGESLDYLITDGADD
IVKMLNDPALNRHNIQVANDARFVLNAGKKKFTGTISLYYYWNNEEEKALATHYGFACGVQHCTRSLENLKGTIHEKNKN
MDYSKVMAFYHPFKVRFYEYYSPRGIPDGVSAALLPVTVTLDIITAPLQFLVVYAVNQ
>SEQF1516_EDU88256.1 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MYLFESLNQLIQTYLPEDQIKRLRQAYLVARDAHEGQTRSSGEPYITHPVAVACILAEMKLDYETLMAALLHDVIEDTPA
TYQDMEQLFGKSVAELVEGVSKLDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIAR
ETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILSEIEGRLQEAGIPCRVSGREKHL
YSIYCKMVLKEQRFHSIMDIYAFRVIVNDSDTCYRVLGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEV
QIRTEDMDQMAEMGVAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFTPEGRIVEL
PAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLTSGQTVEIITAPGARPNAAWLNFVVSSKARAKIRQLLKNLKRD
DSVSLGRRLLNHALGGSRKLNEIPQENIQRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQHGDASIPPATQSHGHLPI
KGADGVLITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETAQEFITEIKVEMFNHQGAL
ANLTAAINTTTSNIQSLNTEEKDGRVYSAFIRLTARDRVHLANIMRKIRVMPDVIKVTRNRN
>SEQF1516_EDU88257.1 hypothetical protein ECH7EC4501_1063 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPRYKNIFVILFIYIATCTENGKENKKQGKSPISRHKK
>SEQF1516_EDU88258.1 putative diguanylate cyclase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVAAVVLVFVFIFCTVLLFHLVQQNRYNTATQLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQF
QALRKSFIPERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLVTIYLLLSLILTVA
ISWCINRLILHPLRNIARELNAIPAQELVGHQLALPRLHQDDEIGMLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNK
ALLMEMLEQVVARKQTTALMIITCETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVHEPWH
AITLGQQVLTIMSERLPIERIQLRPHCSISVAMFYGDLTAEQLYSRAISAAFTARHKGKNQIQFFDPQQMEAAQKRLTEE
SDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQQPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQER
GIMLPLSVNLSVLQLMHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDFGMGYAGL
RQLQHMKSLPIDVLKIDKMFVEGLPEDSSMIAAIIMLAQSLNLQMIAEGVETEAQRDWLAKAGVGIAQGFLFARPLPIEI
FEESYLEEK
>SEQF1516_EDU88259.1 ABC transporter, ATP binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTHLELVPVPPVAQLAGVSQHYGKTVALNNITLDIPARCMVGLIGPDGVGKSSLLSLISGARVIEQGNVIVLGGDMRDPK
HRRDVCPRIAWMPQGLGKNLYHTLSVYENVDFFARLFGHDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCC
ALIHDPELLILDEPTTGVDPLSRAQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWLVAMNAGEVLATGSAEELRQQTQ
SATLEEAFINLLPQAQRQAHQAVVIPPYQPENAEIAIEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMK
MLTGLLPASEGEAWLFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPEAEIPARVAEMSERFKLNDV
EDVLPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLMVDLSRQDKVTIFISTHFMNEAERCDRISLM
HAGKVLASGTPQELVEKRGAASLEEAFIAYLQEAAGQSNEAEAPPVIHDTTHAPRQGFSLRRLFSYSRREALELRRDPVR
STLALMGTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPLLTSYDELDRRMRAGDITVAIEIP
PNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWLQDVASRQSTPSSQSGLMNIETRYRYNPDVKSLPAIVPA
VIPLLLMMIPSMLSALSVVREKELGSIINLYVTPTTRSEFLLGKQLPYIALGMLNFFLLCGLSVFVFGVPHKGSFLTLTL
AALLYIIIATGMGLLISTFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGRWIGEVYPTSHFLTIARGTFSKALD
LTDLWQLFIPLLIAIPLVMGLSILLLKKQEG
>SEQF1516_EDU88260.1 sensor histidine kinase UhpB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFPFGLRLGLMLQCPRGYWPVLLGAEWLLIYWLTQAVGLTHF
SLLMIGSLLTLLPVALISRYRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWHYLA
NNTWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALPIIALAWHYGWQGALIATLMNAIALI
ASQTWRDHPVDLLLSLLVQSLTGLLLGAGIQRLRELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAI
RTQAGIVQRLAADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIEE
SALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWLQDERLMLVIEDDGSGLPPGSGQQGFGLTGMRERVTALGGTLTI
SCLHGTRVSVSLPQRYV
>SEQF1516_EDU88261.1 hypothetical protein ECH7EC4501_0848 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MCEEKYQYGLVMGKRAENVDGLLLPNKSHIYHGDINIFLIVSI
>SEQF1516_EDU88262.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRLTQYKKEILSYFTPDNLAWVRGEIGNPPFDVSGVAYLLYGMDSHNNRYQLESTRRTLEAMVRDGLLERVNVYERREGT
GDGVRRKVARYGLPGHSVVVRDGEGRNGAIDGECIRINATDVVLVDGQ
>SEQF1516_EDU88263.1 maltose-6'-phosphate glucosidase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTKFSVVVAGGGSTFTPGIVLMLLANQDRFPLRALKFYDNDGSRQEVIAEACKVILKEKAPDIAFSYTTDPEVAFSDVDF
VMAHIRVGKYPMRELDEKIPLRHGVVGQETCGPGGIAYGMRSIGGVLELVDYMEKYSPNAWMLNYSNPAAIVAEATRRLR
PNAKILNICDMPIGIESRMAQIVGLQDRKQMRVRYYGLNHFGWWTSIEDLQGNDLMHQLRQYVSKHGYVPPQQDTHTEAS
WNDTYAKARDVQALDPDTLPNTYLKYYLFPDYVVQHSNPEHTRANEVMEHREKQVFDACRAITAAGNSAAGKLEIDEHAS
YIVDLAAAIAFNTQERMLLIVPNNGAIHNFDDEAMVEIPCLVGHNGPEPLVVGDIPQFQKGLMSQQVAVEKLVVDAWEQR
SYQHLWQAITLSKTVPSASVAKAILDELLEANKAYWPELR
>SEQF1516_EDU88264.1 L-lactate permease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLWPI
AWIIIAAVFVYKISVKTGQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLC
LIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWRGIKETWPAVVVAGGSFAIAQYL
SSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFRFGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPP
FKALFASGGALYEWVINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPSDAISTFGS
TLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLGWLGVFLTGSDTSSNALFAALQATAAQQIGV
SDLLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVLTWMIP
>SEQF1516_EDU88265.1 cold shock DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKSLDEGQKVSFTIESGAKGPAAGNVTSL
>SEQF1516_EDU88266.1 hypothetical protein ECH7EC4501_0625 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MATTAAKNCASMGMPKKVIISEVKIHFLFGIILSILPE
>SEQF1516_EDU88267.1 ribosomal protein L34 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTVSK
>SEQF1516_EDU88268.1 ATP synthase F0, B subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGLASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQAN
KRRSQILDEAKAEAEQERTKIVAQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL
>SEQF1516_EDU88269.1 D-xylose ABC transporter, ATP-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPYLLEMKNITKTFGSVKAIDNVSLRLNAGEIVSLCGENGSGKSTLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTER
KGIAIIHQELALVKELTVLENIFLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQ
VRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDGQHIGTRDAAGMSEDDIITMMVG
RELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKRVNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIY
IDGKQVDIRNCQQAIAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAAEQKCILESIQQLKVKTSSPD
LAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQLVQQGIAVIVISSELPEVLGLSDRVLVMHE
GKLKANLINHNLTQEQVMEAALRSEHHVEKQSV
>SEQF1516_EDU88270.1 3-dehydroquinate synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNETLAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAV
LDTVFTALLQKPHGRDTTLVALGGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGTFFNWLEENLDALLRLDGPAMAYCIRRCCELKAEVVAADERETGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAARTSERLGQFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHML
RDKKVLAGEMRLILPLAIGKSEVRSGVSHELVLNAIADCQSA
>SEQF1516_EDU88271.1 PEP-dependent sugar transporting PTS family, IIA component [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQGIHFQENYIQRLPAGLSVEQIIRQLAQPLVAAELVVPDFADHVLKREATYPTGLPTEPPCVAIPHTDHKHVRHNAIAV
GILPEPVEFADMGGDPDPVPVRVIFLLALSESNKQLNALGWIMEMIQDTPFMQALLAMETTEIHTVILNKMKERGEI
>SEQF1516_EDU88272.1 biotin sulfoxide reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNSSSRYSVLTAAHWGPMLVETDGETVFSSRGALATGMENSLQSAVRDQVHSNTRVRFPMVRKGFLASPENPQGIRGQD
EFVRVSWDEALDLIHQQHKRIREAYGPASIFAGSYGWRSNGVLHKASTLLQRYMALAGGYTGHLGDYSTGAAQAIMPYVV
GGSEVYQQQTSWPLVLEHSDVVVLWSANPLNTLKIAWNASDEQGLSYFSALRDSGKKLICIDPMRSETVDFFGDKMEWVA
PHMGTDVALMLGIAHTLVENGWHDEAFLARCTTGYAVFASYLLGESDGIAKTAEWAAEICGVNAEKIRELAAIFHQNTTM
LMAGWGMQRQQFGEQKHWMIVTLAAMLGQIGTPGGGFGLSYHFANGGNPTRRAAVLSSMQGSLPGGCDAVDKIPVARIVE
ALENPGGAYQHNGMDRHFPDIRFIWWAGGANFTHHQDTNRLIRAWQKPELVVISECFWTAAAKHADIVLPATTSFERNDL
TMTGDYSNQHLVPMKQVVPPRYEARNDFDVFAELSERWEKGGYARFTEGKSELQWLETFYNVARQRGASQQVELPPFTEF
WQANQLIEMPENPDSERFIRFADFCRDPQAHPLKTASGKIEIFSQRIADYAYPDCPGHPMWLVPDEWQGNAEPEQLQVLS
AHPAHRLHSQLNYSSLRELYAVANREPVTIHPDDAQARGIQDGDTVRLWNARGQILAGAVISEGIKPGVICIHEGAWPDL
DLTADGICKNGAVNVLTKDLPSSRLGNGCAGNTALAWLEKYNGPELTLTAFEPPASS
>SEQF1516_EDU88273.1 RNA 3'-phosphate cyclase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKRMIALDGAQGEGGGQIMRSALSLSMITGQPFTITGIRAGRAKPGLLRQHLTAVKAATEICGATVEGAELGSQRLVFRP
GTVRGGDYRFAIGSAGSCTLVLQTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFY
PAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAASFSLHEQNIHNLPRDQGPGNTVSLEV
ESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLASPAAVGEYLADQLVLPMALAGAGQFTVAHPSCHLLTNIAVVERFL
PVRFTLAETDGVTRVMITKLTD
>SEQF1516_EDU88274.1 hypothetical bacteriophage protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASKNTGLTASSKTHPEFMCGDIYRNEYGSHMTMISRGKK
>SEQF1516_EDU88275.1 lipopolysaccharide core biosynthesis protein RfaY [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTERFLKSCIKKDYYENLIYQTDRVRGEGIQSINDYFLLAERKTLNFAHYYIMLIEYIEGVGLNEYLEISEDLKDQLSES
IKELHQHGMVSGDPHKGNFIVSEKGLRLIDLSGKKTTAVLKAKDRIDLERHYNIKNELKDFGYTYLIFKKKIKKVIRDVK
VKLGLKSK
>SEQF1516_EDU88276.1 transcriptional regulator, GntR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKSLSKSSQIPLYQQVVEWIRESIYTGDLVEDDRIPSEYQIMDMLDVSRGTVKKAVAQLVKEGVLIQVQGKGTFVKKENV
AYPLGEGLLSFAESLESQKIHFTTEVITSRIESANRYVAEKLRITPGQDILYLERLRSIGDEKAMLIENRINIELCPGIA
EIDFNQHNLFPTIESLSQRKIRYSESRYAARLIGNERGHFLDISEDAPVLHLEQLVFFSRGLPIEFGNVWLKGNKYYLGT
VLQRREVS
>SEQF1516_EDU88277.1 fabA-like domain protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSHYLSPGAYLPHDAPMLLLEDVVSVSDDSAVCRVTVSPSGVLAPFLDPDGNLPGWFTLELMAQTVGVWSGWHRHQQGKN
SIELGMILGARELLCTTGILPAGQTLTITVKLLMQDDRFGSFECSINDGEATGRINTFQPTAEELTTLFQQGAS
>SEQF1516_EDU88278.1 ATP synthase F1, epsilon subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLTAIKPGMIRIVKQHGHEEFIYLSGGILEVQLGNVTVL
ADTAIRGQDLDEARAMEAKRKAEEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM
>SEQF1516_EDU88279.1 HdeB protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGYKINISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFIDLNPKAMTPVAWWMLHEETVYKGGDTVTLNETD
LTQIPKVIEYCKKNPQKNLYTFKNQASNDLPN
>SEQF1516_EDU88280.1 transcriptional regulator, LysR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLEKIINNAICALLFRCEQQSVKEMDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQLGTQLLQRTTRRV
KLTPEGMTYYQRAKDVLSNLNELDGLFQQDATSISGKLRIDIPPGIAKSLLLPHLSEFLYQHPGIELELSSHDRPVDILH
DGFDCVIRTGALPEDGVIARPLGKLTMVNCASPHYLTRFGYPQNPDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKS
GGMLTVNSSENYLAAGLAGLGIIQIPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQRRELSRRVNLFMQWLAGVMKE
YLD
>SEQF1516_EDU88281.1 EscU [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKTEKPTPKKLRDLKKKGDVTKSEEVMAAVQSLILFSFFSLYGMSFFVDIVGLVNTTIDSLNRPFLYAIREILGAVLN
IFLLYILPISLIVFVGTVTTGVSQIGFIFAVEKIKPSAQKISVKNNLKNIFSVKSIFELLKSVFKLVIIVLIFYFMGHSY
ANEFANFTGLNAYQALVVVAFFVFLLWKGVLFGYLLFSVFDFWFQKHEGLKKMKMSKDEVKREAKDTDGNPEIKGERRRL
HSEIQSGSLANNIKKSTVIVKNPTHIAICLYYKLGETPLPLVIETGKDAKALQIIKLAELYDIPVIEDIPLARTLYKNIH
KGQYITEDFFEPVAQLIRIAIDLDY
>SEQF1516_EDU88282.1 acetolactate synthase, isozyme I, small subunit [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPIQDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQR
NQSDPTMFNKIAVFFQ
>SEQF1516_EDU88283.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGEVAAASPWVLLYSYLLTFQYHPEKYERVRDNARKSLHLSEILNIDAVNRLIHYCNRK
>SEQF1516_EDU88284.1 type III secretion outer membrane pore, YscC/HrcC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKISFFIFTALFCCSAQAAPSSLEKRLGKSEYFIITKSSPVRAILNDFAANYSIPVFISSSVNDDFSGEIKNEKPVKVL
EKLSKLYHLTWYYDENILYIYKTNEISRSIITPTYLDIDSLLKYLSDTISVNKNSCNVRKITTFNSIEVRGVPECIKYIT
SLSESLDKEAQSKAKNKDVVKVFKLNYASATDITYKYRDQNVVVPGVVSILKTMASNGSLPSTGKGAVERSGNLFDNSVT
ISADPRLNAVVVKDREITMDIYQQLISELDIEQRQIEISVSIIDVDANDLQQLGVNWSGTLNAGQGTIAFNSSTAQANIS
SSVISNASNFMIRVNALQQNSKAKILSQPSIITLNNMQAILDKNVTFYTKVSGEKVASLESITSGTLLRVTPRILDDSSN
SLTGKRRERVRLLLDIQDGNQSTNQSNAQDASSTLPEVQNSEMTTEATLSAGESLLLGGFIQDKESSSKDGIPLLSDIPV
IGSLFSSTVKQKHSVVRLFLIKATPIKSASSE
>SEQF1516_EDU88285.1 translocated intimin receptor Tir [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MPIGNLGHNPNVNNSIPPAPPLPSQTDGAGGRGQLINSTGPLGSRALFTPVRNSMADSGDNRASDVPGLPVNPMRLAASE
ITLNDGFEVLHDHGPLDTLNRQIGSSVFRVETQEDGKHIAVGQRNGVETSVVLSDQEYARLQSIDPEGKDKFVFTGGRGG
AGHAMVTVASDITEARQRILELLEPKGTGESKGAGESKGVGELRESNSGAENTTETQTSTSTSSLRSDPKLWLALGTVAT
GLIGLAATGIVQALALTPEPDSPTTTDPDAAASATETATRDQLTKEAFQNPDNQKVNIDELGNAIPSGVLKDDVVANIEE
QAKAAGEEAKQQAIENNAQAQKKYDEQQAKRQEELKVSSGAGYGLSGALILGGGIGVAVTAALHRKNQPVEQTTTTTTTT
TTTSARTVENKPANNTPAQGNVDTPGSEDTMESRRSSMASTSSTFFDTSSIGTVQNPYADVKTSLHDSQVPTSNSNTSVQ
NMGNTDSVVYSTIQHPPRDTTDNGARLLGNPSAGIQSTYARLALSGGLRHDMGGLTGGSNSAVNTSNNPPAPGSHRFV
>SEQF1516_EDU88286.1 IS66 family element, orf1 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTLDAAAEQPESLAEDPETLSISCEVTFRHGTLRFNGNVSEKLLTLLIQELKR
>SEQF1516_EDU88287.1 NADPH-dependent FMN reductase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIADIPLYDADVQQEEGFPATVEALAEQIRQADGVVIVT
PEYNYSVPGGLKNAIDWLSRLPDQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQT
GEVIDQGTLDHLTGQLTAFGEFIQRVKI
>SEQF1516_EDU88288.1 transcriptional regulator GadE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIFLMTKDSFLLQGFWQLKDNHEMIKINSLSEIKKVGNKPFKVIIDTYHNHILDEEAIKFLEKLDAERIIVLAPYHISKL
KAKAPIYFVSRKESIKNLLEITYGKHLPHKNSQLCFSHNQFKIMQLILKNKNESNITSTLNISQQTLKIQKFNIMYKLKL
RRMSDIVTLGITSYF
>SEQF1516_EDU88289.1 ATP-dependent DNA helicase RecG [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTGRLLDAVPLSSLTGVGAALSNKLAKINLHTVQDLLLHLPLRYEDRTHLYPIGELLPGVYATVEGEVLNCNISFGGRRM
MTCQISDGSGILTMRFFNFSAAMKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRVQGDLSTPELQETLTPVYPTTEGVKQ
ATLRKLTDQALDLLDTCAIEELLPPELSQGMMTLPEALRTLHRPPPTLQLSDLETGQHPAQRRLILEELLAHNLSMLALR
AGAQRFHAQPLSANDALKNKLLAALPFKPTGAQARVVAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQV
ALMAPTELLAEQHANNFRNWFEPLGIEVGWLAGKQKGKARLSQQEAIASGQVQMIVGTHAIFQEQVQFNGLALVIIDEQH
RFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDELPPGRTPVTTVAIPDTRRTDIIDRVRHACI
TEGRQAYWVCTLIEESELLEAQAAEATWEELKLALPELNVGLVHGRMKPAEKQAVMASFKQGELHLLVATTVIEVGVDVP
NASLMIIENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQIRLQVLRDSNDGFVIAQKDLEIRGPGELLGTRQ
TGNAEFKVADLLRDQAMIPEVQRLARHIHERYPQQAKALIERWMPETERYSNA
>SEQF1516_EDU88290.1 dipeptide ABC transporter, permease protein DppB [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGI
SMKSRIPVWEEFVPRFQATLELGVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW
NLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA
RAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILV
NLLVDLLYGVVNPRIRHKK
>SEQF1516_EDU88291.1 tryptophanase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSEDVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSY
YALAESVKNIFGYQYTIPTHQGRGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFD
TGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAKKYDIPVVMDSARFAENAYFIKQ
REAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPMGGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAV
GLYDGMNLDWLAYRIAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIRAVEIGSFL
LGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENASNIKGLTFTYEPKVLRHFTAKLKEV
>SEQF1516_EDU88292.1 catabolite gene activator [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR
>SEQF1516_EDU88293.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKWFAAIAVVGALAGCARTAPIDQVHSTVSAGHTQEQVKKAILKAGVERKWIMSEAGQGIIKARQQSRDHSAEIRINYTA
SSYDINYENSQNLQASGGQIHKNYNRWVRNLDKDIQLNLSAGADL
>SEQF1516_EDU88294.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKPPLFFIVIIGLIIVAASFRFMQQRREKADNDMAPLQQKLVLVSNKREKPINDRRSRQQEVTPAGTSMRYEASFKPQS
GGMEQTFRLDAQQYHALTVGDKGTLSYKGTRFVSFVGEQ
>SEQF1516_EDU88295.1 protein GntX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVCHQMLFIRYCSLLTYKDEHMLTVPGLCWLCRMPLALGHWGICSVCSRAARTDKTLCPQCGLPATHSHLPCGRCLQKPP
PWQRLVTVADYAPPLSLLIHQLKFSRRSEIASALSRLLLLEVLHARRTTGLQLPDRIISVPLWQRRHWRRGFNQSDLLCQ
PLSRWLHCQWDSEAITRTRATATQHFLSARLRRRNLKNAFRLELPVQGRHMVIVDDVVTTGSTVAEIAQLLLRNGAATVQ
VWCLCRTL
>SEQF1516_EDU88296.1 phosphate ABC transporter, permease protein PstC [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAATKPAFNPPGKKGDIIFSVLVKLAALIVLLMLGGIIVSLIISSWPSIQKFGLAFLWTKEWDAPNDIYGALVPIYGTLV
TSFIALLIAVPVSFGIALFLTELAPGWLKRPLGIAIELLAAIPSIVYGMWGLFIFAPLFAVYFQEPVGNIMSNIPIVGAL
FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPFTKNGVIGGIMLGLGRALG
ETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFAEAESGLHVAALMELGLILFVITFIVLAASKFMIMRLAKNEGAR
>SEQF1516_EDU88297.1 hypothetical bacteriophage protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTANHQEAIPTTGYIRRCNLAKLLDTSVSTIDRWVRIGKLPKPTKLGEKNTVFNAVEINHWLNERRNNTKQ
>SEQF1516_EDU88298.1 type III secretion apparatus needle protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLSEITQQMGEVGKTLSDSVPELLNSTDLVNDPEKMLELQFAVQQYSAYVNVESGMLKTIKDLVSTISNRSF
>SEQF1516_EDU88299.1 inner membrane protein YhhT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METPQPDKTGMHILLKLASLVVILAGIHAAADIIVQLLLALFFAIVLNPLVTWFIRRGVQRPVAITIVVVVMLIALTALV
GVLAASFNEFISMLPKFNKELTRKLFKLQEMLPFLNLHMSPERMLQRMDSEKVVTFTTALMTGLSGAMASVLLLVMTVVF
MLFEVRHVPYKMRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGVIVWLGLELMGVQFALMWAVLAFLLNYVPNIG
AVISAVPPMIQVLLFNGVYECILVGALFLVVHMVIGNILEPRMMGHRLGMSTMVVFLSLLIWGWLLGPVGMLLSVPLTSV
CKIWMETTKGGSKLAILLGPGRPKSRLPG
>SEQF1516_EDU88300.1 IS66 family element, transposase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQLDKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTL
TGRVYDPAVQRPLRQTRTRKPFPESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
DAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELRRSLLSGWVDACCRLLSPLEEALHGYVMT
DGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNAGSALAPAVWFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELY
RNGGITEAACWAHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLESWLREKMKT
LSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLGRKNFLFFGSDHGGERGAPLYSLIGTCKLNDVDP
ESYLRHVLGVIADWPVNRVSELLPWRIALPAE
>SEQF1516_EDU88301.1 type III secretion system protein, YseE family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MITITELEDEIIKNKEAANVFIEKINDKKNEIHEKMKHPLDKVTYNEAKELLIACDAAIRTIEIMRIRINNK
>SEQF1516_EDU88302.1 hypothetical bacteriophage protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTERSPTEIIHGIIEEQEERELILMIEEQRERQHKQEATQPDSVTAKNYARVVAEVMRREGTELNGQDCLVIRTRVLGML
AARRRQEQRQNAAPYQWHKPERLRR
>SEQF1516_EDU88303.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRAAEVIEQHRRVILNEESWTRVMDALSNPPSPGEKLKR
AAKRLQGM
>SEQF1516_EDU88304.1 lipopolysaccharide heptosyltransferase I [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRVLIVKTSSMGDVLHTLPALTDAQQAIPEIKFDWVVEEGFAQIPSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFRE
ALQAENYDAVIDAQGLVKSAALVTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQ
GDYAIAQHFLTNLPTDAGEYAVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWGAPHEEERAKRLAEGFAYVEVLP
KMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNITVYGPTDPGLIGGYGENQVECRSTSMSLADLPAQTVFQNLNLEI
ITNKLTSEIR
>SEQF1516_EDU88305.1 lipopolysaccharide core biosynthesis protein RfaP [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVELKEPFATLWRGKDPFEEVKTLQGEVFRELETRRTLRFEMAGKSYFLKWHRGTTLKEIIKNLLSLRMPVLGADREWNA
IHRLRDVGVDTMYGVAFGEKGMNPLTRTSFIITEDLTPTISLEDYCADWATNPPDVRVKRMLIKRVATMVHDMHAAGINH
RDCYICHFLLHLPFSGKEEELKISVIDLHRAQLRTRVPRRWRDKDLIGLYFSSMNIGLTQRDIWRFMKVYFAAPLKDILK
QEQGLLSQAEAKATKIRERTIRKSL
>SEQF1516_EDU88306.1 putative DNA-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTAKTKFKSPAFEAIHSAAAGLSSVNAISAETMRTFDKACLTSVQDLQPVEIKALREKLKVSQPVFAHYLNTSVSTVQKW
ESGAKRPNGISLKLLSIVQKHGLEVLL
>SEQF1516_EDU88307.1 4-alpha-glucanotransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MESKRLDNAALAAGISPHYINAHGKPQSISAETKRRLLDAMHQRTATKVAVTPVPNVMVYTSGKKMPMVVEGSGEYSWLL
TTEEGTQYKGHITGGKAFNLPTKLPEGYHTLTLTQEDQRGHCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWG
IGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNAVEDFHLSEEAQAWWQLPTTQQT
LQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDEQMAAFRQFVADQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPE
MYQNVDSPEVRQFCEEHRDDVDFYLWLQWQAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAETWCDRELYCLKASVG
APPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHVMSMLRLWWIPYGETADQGAYVHYPVDDLLS
ILALESKRHRCMVIGEDLGTVPVEIVGKLRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWESGD
LTLGKTLGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRYIADSNSALLGLQPEDW
LDMAEPVNIPGTSYQYKNWRRKLSATLETMFADDGVNKLLKDLDRRRRAAAKKK
>SEQF1516_EDU88308.1 aldehyde dehydrogenase B [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTNNPPSAQIKPGEYGFPLKLKNRYDNFIGGEWVAPADGEYYQNLTPVTGQLLCEVASSGKRDIDLALDAAHKVKDKWAH
TSVQDRAAILFKIADRMEQNLELLATAEAWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGVVNVVNGAGGEIGEYLATSKRIA
KVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNIFFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIY
ERFMERAIRRVESIRSGNPLDSVTQMGAQVSHGQLETILNYIDIGKKEGADVLTGGRRKLLEGELKDGYYLEPTILFGQN
NMRVFQEEIFGPVLAVTTFKTMEEALELANDTQYGLGAGVWSRNGNLAYKMGRGIQAGRVWTNCYHAYPAHAAFGGYKQS
GIGRETHKMMLEHYQQTKCLLVSYSDKPLGLF
>SEQF1516_EDU88309.1 integral membrane protein, MarC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVRELLIALLVMLVFLFAGEKILAFLSLRAETVSISGGIIL
FLIAIKMIFPSASGNSSGLPAGEEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG
>SEQF1516_EDU88310.1 osmolarity sensor protein EnvZ [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRRLRFSPRSSFARTLLLIVTLLFASLVTTYLVVLNFAILPSLQQFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREI
YRELGISLYSNEAAEEAGLRWAQHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPL
FRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTRAFNHMAAGVKQLADDRTLLMAG
VSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEECNAIIEQFIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIE
TALYPGSIEVKMHPLSIKRAVANMVVNAARYGNGWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVRGDSARTIS
GTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQSTTKEG
>SEQF1516_EDU88311.1 16S rRNA methyltransferase RsmD [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKPNHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLFNWLAPVIVDAQCLDCFAGSGALGLEALSRYAAGATL
IEMDRAVSQQLIKNLATLKAGNARVVNSNAMSFLAQKGTPHNIVFVDPPFRRGLLEETINLLEDNGWLADETLIYVESEV
ENGLPTVPANWSLHREKVAGQVAYRLYQREAQGESDAD
>SEQF1516_EDU88312.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGIIAQNKISSLGMLFGAIALMMGIIHFSFGPFSAPPPTLESIVADKTAEIKRGLLAGIKGEKITTVERKEDVDVDKILD
QSGIALAIAALLCAFIGGMRKENRWGIRGARVFGGGTLAFHTLLFGIGIVCSILLIFLIFSFLTGGSLV
>SEQF1516_EDU88313.1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSVSKKPMVLVILDGYGYREEQQDNAIFSAKTPVMDALWANRPHTLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQD
LTRLDVEIKDRAFFANPVLTGAVDKAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPR
SAESSLKKFEEKFAALGKGRVASIIGRYYAMDRDNRWDRVEKAYDLLTLAQGEFQADTAVAGLQAAYARDENDEFVKATV
IRAEGQPDAAMEDGDALIFMNFRADRAREITRAFVNADFDGFARKKVVNVDFVMLTEYAADIKTAVAYPPASLVNTFGEW
MAKNDKTQLRISETEKYAHVTFFFNGGVEESFKGEDRILINSPKVATYDLQPEMSSAELTEKLVAAIKSGKYDTIICNYP
NGDMVGHTGVMEAAVKAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQMRDPATGQAHTAHTNLPVPLIYVGDKNVKA
VAGGKLSDIAPTMLSLMGMEIPQEMTGKPLFIVE
>SEQF1516_EDU88314.1 fimbrial protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPNMIVGALALTSVFMAGHLQAADGTVHFRGEIIDSTCEVTPETKDQVVDLGKVNRTAFSGVDDVAAPTAFSIDLTQCP
ETFKSAAIRFDGNEDAHGNGNLAIGTPLDNSNDAAAGISPSDNSGDYTGAGAVSAAKGVAIRLYNRADNTQVKLYENSAS
TPISNGNASMKFMARYIATETTIDPGTANADSQFTVEYIK
>SEQF1516_EDU88315.1 sulfurtransferase TusA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKG
G
>SEQF1516_EDU88316.1 D-xylose ABC transporter, permease protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFTWTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIIS
AEIDLSVGSMMGLLGGVAAICDVWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVVGRQALTAIIVLGAIWLLNDYRG
VPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLEAARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGN
IAELDAIAACVIGGTSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRRS
>SEQF1516_EDU88317.1 high-affinity branched-chain amino acid ABC transporter, ATP-binding protein LivF [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MEKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDDKDITDWQTAKIMRE
AVAIVPEGRRVFSRMTVEENLAMGGFFAERDQFQERIKWVYELFPRLHERRVQRAGTMSGGEQQMLAIGRALMSNPRLLL
LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLSDTGDALLANEAVRSAYLGG
>SEQF1516_EDU88318.1 nickel-responsive transcriptional regulator NikR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEATQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHD
LSVATLHVHINHDDCLEIAVLKGDMGDVQHFADDVIAQRGVRHGHLQCLPKED
>SEQF1516_EDU88319.1 glutathione S-transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVTQFNPLGKVPVLVTEEGECWFDSPIIAEYIELMNVAPAML
PRDPLESLRVRKIEALADGIMDAGLVSVREQARPAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIAC
AVGYLNFRRVAPGWCVDRPHLVKLVENLFSRESFARTEPPKA
>SEQF1516_EDU88320.1 periplasmic-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MASAAKTAVKRKKLFTAVLALSWAFSVTAAERIVVAGGSLTELIYAMGAGERVVGVDETTSYPPETAKLPHIGYWKQLSS
EGILSLRPDSVITWQDAGPQIVLDQLRAQKVNVVTLPRVPATLQQMYANIRQLAKTLQVPEQGEALVTQISQRLERVQQN
VATKKAPVKAMFILSAGGSAPQVAGKGSVADAILSLAGAENVATHQQYKSYSAESLIAANPEVIVVTSQMVDGDINRLRS
IAGITHTAAWKNQRIITVDQNLILGMGPRIADVVESLHQQLWPQ
>SEQF1516_EDU88321.1 aminodeoxychorismate synthase, component II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKPQKVVISPGPCTPDEAGISLDVIRHYAGRLPILGVCL
GHQAMAQAFGGKVVRAAKVMHGKTSPITHNGEGVFRGLANPLTVTRYHSLVVEPDSLPACFEVTAWSETREIMGIRHRQW
DLEGVQFHPESILSEQGHQLLANFLHR
>SEQF1516_EDU88322.1 phosphatase yidA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTGRPYAGVHNYLKELHMEQPGDYCITYNGALVQKAADG
NTVAQTALSYDDYRFLEKLSREVGSHFHALDRTTLYTANRDISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEP
AILDQAIARIPQEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAIGDQENDIAMIEYAGVGVAMDNA
IPSVKEVANFVTKSNLEDGVAFAIEKYVLN
>SEQF1516_EDU88323.1 2-dehydro-3-deoxygluconokinase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPAALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRM
ENRLPGLYYIETDSTGERTFYYWRNEAAAKFWLESDQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANG
GKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTHNAGVKEVVVKRGADSCLVSIAG
EGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLTGGSAENAAKRGHLTASTVIQYRGAIIPREAMPA
>SEQF1516_EDU88324.1 gluconate transporter GntU [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTTLTLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSGMPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILH
ETGAVDQIAVKMLKSFGHSRAHYAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVP
GPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHLGEGKMPSFGFSLSLILLPLVLV
GLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLVAIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVL
VDSGVGPALGEALTGMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNYSGAQMAALSICIAGGSIVVSHV
NDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIAFQLLS
>SEQF1516_EDU88325.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSQTRNKELLDKKIRSEIEAIKKIIAEFDVVKESVNELSEKAKTDPQAAEKLNKLIEGYTYGEERKLYDSALSKIEKLIE
TLSPARSKSQSTMNQRNRNNRKIV
>SEQF1516_EDU88326.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MGTAAISHLRYDLNKYALSLRKTATLASTFFIESPLVRFEYLQEIENTINDITHRFNSSYDINEKARLINELKMESETAR
KEYQLFRQGNYDKYITTDIFEEHGLIKYVNLSFDIVASVGQVVGGVGALKFGKVVHSNRIKGIGVTLVAHGANNFYESLS
PLFFNEYDSGPIRELYRVIAKKMGGDINSADYAYSIVDFSITAYGGYSGMKIVPKYNRLIRPSLGNRPGTGRLFHYTSVD
FKNKFSLKPTPLKIIQISSTVKKFKVTFYDENTNLRIKHGLNNHMPHQLLMNISGTTTGAGIQ
>SEQF1516_EDU88327.1 hypothetical protein ECH7EC4501_0918 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIGFMIDFVIGFMIDLRSFLRNFLRIFSGIFHPIGGASEGGL
>SEQF1516_EDU88328.1 Beta-ketoacyl synthase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIYISAVGMINALGNNLDEIATNLTRGVAPGMRPRAGWLQGHPQAVLAGVDGELPLIPEKFAAHRSRNNQILLAALAQIQ
PQVDDAIAKYGRERIAIVLGTSTSGLHEGDTHVNLRTHGQPSTTWHYAQQELGDPSRFLSHWLALDGPAYTLSTACSSSA
RAIISGRRLIEAGLVDAAIVGGADTLSRMPINGFHSLESLSPTLCQPFGRDRAGITIGEGAGLMLLTREPQPIALLGVGE
SSDAYHISAPHPQGEGAIRAINQALTDAQLTPDDVGYINLHGTATQLNDQIESMVVNALFGERVPCSSTKHLTGHTLGTA
GITEAAISMLILQRDLPLPAQDFSLSPRDPTLPPCGIIEKPQPLARPVILSNSFAFGGNNASILLGRVS
>SEQF1516_EDU88329.1 ST22 protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNLLVKRNVEEFLRLLGNDFYLFDNRVEIDFNGFSFFIEIIDNNVFVTFALEYNENAFFSFFSALAPERTQGVIEHIFVY
DNKLCLSCLLTNIDVFFLMNTFQQHVQIIERVRRMTS
>SEQF1516_EDU88330.1 chromosomal replication initiator protein DnaA [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPNRFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGT
KSVTQTPQAAVTSNVAAPAQVAQTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADN
PGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALLIDDIQFF
ANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEINGVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGE
VAFFIAKRLRSNVRELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVADLLSKRRS
RSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREESHDIKEDFSNLIRTLSS
>SEQF1516_EDU88331.1 inner membrane protein YhjX [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTPSNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLDAPVSQVAFSFGLLSLGLAISSSVAGKLQERFGVKRVTI
ASGILLGLGFFLTAHSDNLMMLWLSAGVLVGLADGAGYLLTLSNCVKWFPERKGLISAFAIGSYGLGSLGFKFIDTQLLE
TVGLEKTFVIWGAIALVMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMRKPQYWMLAVMFLTACMSGLYVIGVAKDI
AQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDKIARIRVITIGQVISLVGMAALLFAPLNAVTFFAAIACVAFNFGG
TITVFPSLVSEFFGLNNLAKNYGVIYLGFGIGSICGSIIASLFGGFYVKFYVIFALLILSLALSTTIRQPEQKVLREAHI
>SEQF1516_EDU88332.1 transcriptional regulator GntR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAALDELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAE
VLRGIESVTDAHGYQTMLAHYGYKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSQSPCLDIAV
GFDNFEAARQMTTAIIARGHRHIAYLGARLDERTIIKQKGYEQAMLDAGLVPYSVMVEQSSSYSSGIELIRQARREYPQL
DGVFCTNDDLAVGAAFECQRLGLKVPDDMAIAGFHGHDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGESVTPKMLD
LGFTLSPGGSI
>SEQF1516_EDU88333.1 serine O-acetyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSCEELEIVWNNIKAEARTLADCEPMLASFYHATLLKHENLGSALSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIAS
AACDIQAVRTRDPAVDKYSTPLLYLKGFHALQAYRIGHWLWNQGRRALAIFLQNQVSVTFQVDIHPAAKIGRGIMLDHAT
GIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAGAKILGNIEVGRGAKIGAGSVVLQPVPPHTTAAGVP
ARIVGKPDSDKPSMDMDQHFNGINHTFEYGDGI
>SEQF1516_EDU88334.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKKQSSTPHDALFKLFLRQPETARDFLAFHLPAPIHALCDMKTLKLESSSFIDDDLRESYSDVLWSVKTEQGPGYIYCL
IEHQSTSNKLIAFRMMRYAIAAMQNHLDAGYKTLPMVVPLLFYHGIESPYPYSLCWLDCFADPKLARQLYASAFPLIDIT
VMPDDEIMQHRRMTLLELIQKHIRQRDLMGLVEQMACLLSSGYANDRQIKGLFNYILQTGDAVRFNDFIDGVAERSPKHK
ESLMTIAERLRQEGEQSKALHIAKIMLESGVPLADIMRFTGLSEEELAAASQ
>SEQF1516_EDU88335.1 hypothetical protein ECH7EC4501_1028 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MAESVKQICLIAHIITGKNVPKYLKQSKFNALLKKKDKKSPTRMAGQRE
>SEQF1516_EDU88336.1 maltose regulon activator MalT [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYGKTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIA
AVQQATNGHCAICETMAQKRQYASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR
NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGWATALQLIALSARQNTHSAHKSA
RRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAILRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCY
HPLFGNFLRQRCQWELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSLLEESLKAL
PWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAEFNALRAQVAINDGNPDEAERLAKLALEELP
PGWFYSRIVATSVLGEVLHCKGELTRSLALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINE
QHLEQLPMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGDLDNARSQLNRLENLLG
NGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFANNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARS
LRLMSDLNRNLLLLNQLYWQAGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRILR
EINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQIAGELEVAATTIKTHIRNLYQKLGV
AHRQAAVQHAQKLLKMMGYGV
>SEQF1516_EDU88337.1 hypothetical protein ECH7EC4501_1069 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTVICKECDSLMTPKGKLLLIDIEGEKYQHFFMKGEEI
>SEQF1516_EDU88338.1 transporter, major facilitator family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKHCCKNVVILMPEPVAEPALNGLRLNLRILSIVMFNFASYLTIGLPLAVLPGYVHDVMGFSAFWAGLVISLQYFATLLS
RPHAGRYADLLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGIGQSFAGTGSTLWGVGVVGSLHIG
RVISWNDIVTYGAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLGRVWLYGMALAL
ASAGFGVIATFITLFYDVKGWDGAAFALTLFSCAFVGTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVATMPWMAKI
GVLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVAIALLLTWR
LKKRPPEHVPEAASSS
>SEQF1516_EDU88339.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDTFNDEVFNYYLEQKGYTIQKEFLCGSAFFIGWRIETPFFSLAYRLDEQELILCSFEARNQTGLNGPVLSLTHLLEEL
YHHFSGIKKISAMKSKIGSDSERQKREELFNYFIRKGAVQQETEDGIWFVMNVNS
>SEQF1516_EDU88340.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNSYIKIDQTGSNKFKITDLYREFNGETKCYDKKCRDMDFSGRNVKEFIRLLSDHDQFEKDQISELTVAANALKLEVAKN
NYNMKYSFDTQTERRMIELIREQKDLIPEKYLHQSGIKKLKLHEDEFSSLLVDAERQVLEGSSFVLCCGEKINSTISELL
SKKITDLTHPTESFTLSEYFSYDVYEEIFKKVVFTPGECDLVRDSLVQDGIKPEKIAKIISCLSSRTGIRNLFYACSQAF
HVANDNAALDVRRAATSVGDTIDVCPSFVALNGRNYHQHVDFSEYGFTQTLCVLGAVVNNANDTFDVANYIYTTKGENII
HNDAEDDSPYVHSDESYRHKDDYWARDNDIRNLRRNFSGNITIATYK
>SEQF1516_EDU88341.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNNNEPDTLPDPAIGYIFQNDILALKQAFSLPGIDYADISQREQLAAALKRWPLLAEFAQQK
>SEQF1516_EDU88342.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKIKQNESMMGSTAMTYDLSEEKLMKLKYKSQHGDSEASFRLYQYYCFTKNNIYKQLRYLEKSASQGNVTAQFNYGVFLS
DTNPTLSEYYNLNRAIYWMEFAVNNGNIDAKSKLQELKKLKRMDRRKNKENP
>SEQF1516_EDU88343.1 putative L-lactate dehydrogenase operon regulatory protein LldR [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIVLPRRLSDEVADRVRALIDEKNLEAGMKLPAERQLAMQLGVSRNSLREALAKLVSEGVLLSRRGGGTFIRWRHDTWSE
QNIVQPLKTLMADDPDYSFDILEARYAIEASTAWHAAMRATPGDKEKIQLCFEATLSEDPDIASQADVRFHLAIAEASHN
IVLLQTIRGFFDVLQSSVKHSRQRMYLVPPVFSQLTEQHQAVIDAIFAGDADGARKAMMAHLSFVHTTMKRFDEDQARHA
RITRLPGEHNEHSREKNA
>SEQF1516_EDU88344.1 protein LpfE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKFKRLLHSGIASLSLVACGVNAATDLGPAGDIHFSITITTKACEMEKSDLEVDMGTMTLQKPAAVGTVLSKKDFTIELK
ECDGISKATVEMDSQSDSDDDSMFALEAGGATGVALKIEDDKGTQQVPKGSSGTPIEWAIDGETTSLHYQASYVVVNTQA
TGGTANALVNFSITYE
>SEQF1516_EDU88345.1 dipeptide ABC transporter, periplasmic dipeptide-binding protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNPQLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAE
KWEVSEDGKTYTFHLRKGVKWHDNKEFKPTREMNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD
NTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQYQKDSRIRYKAFDGYWGTKPQID
TLVFSITPDASVRYAKLQKNECQVMPYPNPADIARMKQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKD
AIIKAVYQGAGVSAKNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRMAEMIQADW
AKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSCAASEQGSNYSKWCYKPFEDLIQPARATDDH
NKRVELYKQAQVVMHDQAPALIIAHSTVFEPVRKEVKGYVVDPLGKHHFENVSIE
>SEQF1516_EDU88346.1 chain B, Crystal Strcuture Of A Type Three Secretion System Protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MIMKDGIYSIIFISNEDSCGEGILIKNGNMITGGDIASVYQGVLSEDEDIILHVHRYNYEIPSVLNIEQDYQLVIPKKVL
SNDNNLTLHCHVRGNEKLFVDVYAKFIEPLVIKNTGMPQVYLK
>SEQF1516_EDU88347.1 putative ribonuclease [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MTQENEIKRPTQDLEHEPIKQLDNSEKGGKVSQALETVTTTAEKVQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLS
MIPILMVSFAAGGFVLASHPMLLQDIFDKILQNISDPTLAATLKNTINTAVQQRTTVGLVGLAVALYSGINWMGNLREAI
RAQSRDVWERSPQDQEKFWVKYLRDFISLIGLLIALIVTLSITSVAGSAQQMIISALHLNSIEWLKPTWRLIGLAISIFA
NYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGFEVIKIVMTYTLPSLMKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWI
ATAEYKDDPRMPGKTQP
>SEQF1516_EDU88348.1 transcriptional regulator, AraC family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLELSMTLPIKVQNGGLFISRGVGRHSARRLESWEIIFVEKGRLTIQEEERIFLVDAGESLLLWPNRQHVGVEDFPADLK
FYWLHFEVKAPDNDPRWLTHLSVPQQTKVVDPQALVALFRQFLSEQEKHQRTPALEFIVLLILQQLTRDARLDEQADGAG
TTLAWKAQKLIRTQYHRPLSTALLARELYCNADYLGRVYRRVFHLTLTEAIHRQRVREAEKLLISEARSLTEVAALCGFN
DVGYFRQIFRKHTGLTPAAWKRRYSKEHINS
>SEQF1516_EDU88349.1 3-deoxy-D-manno-octulosonic-acid transferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRHPLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPI
TVTTMTPTGSERVQSAFGKDVQHVYLPYDLPDALNRFLNKVDPKLVLIMETELWPNLIAALHKRKIPLVIANARLSARSA
AGYAKLGKFVRRLLRRITLIAAQNEEDGARFVALGAKNNQVTVTGSLKFDISVTPQLAAKAVTLRRQWAPHRPVWIATST
HEGEESVVIAAHQALLQQFPNLLLILVPRHPERFPDAINLVRQAGLSYITRSSGEVPSTSTQVVVGDTMGELMLLYGIAD
LAFVGGSLVERGGHNPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITVTDATTLAKEVSSLLTDADYRSFYGRHAVE
VLYQNQGALQRLLQLLEPYLPPKTH
>SEQF1516_EDU88350.1 transglycosylase SLT domain [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKKIILSIILISNYCYASDCFEITGKAYNIDPLILKAIAWNESKCKSGIKSKTNKNGTYDIGIMQINSSHLDLLSKFNIS
EDDLLNDACINISVAGYILASNIKSRGNTWDAVGAYNAGYFNTPNAVELRRQYAMKIYKTYNKLKNNEQIID
>SEQF1516_EDU88351.1 hypothetical protein ECH7EC4501_0760 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLYECLLNVAITFNVTTRDYLLTINFPAFLNTFLYYKSSHPARRTSHIIILFSRFV
>SEQF1516_EDU88352.1 Aec75 [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MLTSGELNPRHQHTVTLYAKGLTCKADTLGSRGYVYMAVYPTPETKK
>SEQF1516_EDU88353.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MNIYIGWLFKLIPLIMGLICIALGGFVLESSGQSEYFVAGHVLISLAAICLALFTTAFIIISQLTRGVNTFYNTLFPIIG
YAGSIITMIWGWALLAGNDVMADEFVAGHVIFGVGMIAACVSTVAASSGHFLLIPKNAAGSKSDGTPVQAYSSLIGNCLI
AVPVLLTLLGFIWSITLLRSADITPHYVAGHVLLGLTAICACLIGLVATIVHQTRNTFSTKEHWLWCYWVIFLGSITVLQ
GIYVLVSSDASARLAPGIILICLGMICYSIFSKVWLLALVWRRTCSLANRIPMIPVFTCLFCLFLASFLAEMAQTDMGYF
IPSRVLVGLGAVCFTLFSIVSILEAGSAKK
>SEQF1516_EDU88354.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMMNSFFPAMALMVLVGCSTPSPVQKAQRVKVDPLRSLNMEALCKDQAAKRYNTGEQKIDVTAFEQFQGSYEMRGYTFRK
EQFVCSFDADGHFLHLSMR
>SEQF1516_EDU88355.1 lipopolysaccharide 1,2-N-acetylglucosaminetransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MVDKIIFTVTPIFSIPPRGAAAVETWMYQVAQRTNFPNRIVCIKNPGYSNYTFVNDNCSIHRVGFSRIYKRLFQKWTRLD
PLPYSQRILNIAHDFPITKESVIVVHNSMKLYTQIRKRAPQARVVIHMHNAFEPKLLEQNVKMIVPSLYLKKYYQSYLAN
ADIEIVPNGIDLETYQSNFQPITRSELNISPEEKIIFYAGRIVPDKGILLLMQSFEKLAAAHKNLKLVVIGDYTEMSKSD
KGAYQRNVREIAKRLKDRCIMLGSIPPEKMHCYYPLADLVVIPSQFQEPFCMVAIEAMGAGKPVLVSTRGGMTEFVKENT
TGFHLKEPMTADSISSDILKTLANPELTAVAKQGQDFVFDHYSWDGVTQRFEEVIHNWFE
>SEQF1516_EDU88356.1 ADP compounds hydrolase NudE [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRPTNREAVMIVPIVDDHLILIREYAVGTESYELGFSKG
LIDPGESVFEAANRELKEEVGFGANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLE
DPDFNEARNVSALFLVREWLKGQGRV
>SEQF1516_EDU88357.1 lipopolysaccharide heptosyltransferase II [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKILVIGPSWVGDMMMSQSLYRTLQARYPQAIIDVMAPAWCRPLLSRMPEVNEAIPMPLGHGALEIGERRKLGHSLREKR
YDRAYVLPNSFKSALVPFFAGIPHRTGWRGEMRYGLLNDVRVLDKEAWPLMVERYVALAYDKGIMRTAQDLPQPLLWPQL
QVSEGEKSYTCNQFSLSSERPMIGFCPGAEFGPAKRWPHYHYAELAKQLIDEGYQVVLFGSAKDHEAGNEILAALNTEQQ
AWCRNLAGETQLDQAVILIAACKAIVTNDSGLMHVAAALNRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDAA
EGYHQSLIDITPQRVLKELNALLLQEEA
>SEQF1516_EDU88358.1 transcriptional regulator, LuxR family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MQIVMFDRQSIFIHGMKISLQQRIPGVSIQGASQADELWQKLESYPEALVMLDGDQDGEFCYWLLQKTVVQFPEVKVLIT
ATDCNKRWLQEVIHFNVLAIVPRDSTVETFALAVNSAAMGIMFLPGDWRTTPEKDIKDLKSLSARQREILTMLAAGESNK
EIGRALNISTGTVKAHLESLYRRLEVKNRTQAAMMLNISS
>SEQF1516_EDU88359.1 phosphate ABC transporter, periplasmic phosphate-binding protein PstS [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKWADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGAS
DAPLSDEKLAQEGLFQFPTVIGGVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRR
ADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGYVEYAYAKQNNLAYTKLISADGK
PVLPTEENFANAAKGADWSKTFAQDLTNQKGEDAWPITSTTFILIHKDQKKPEQGTEVLKFFDWAYKTGAKQANDLDYAS
LPDSVVEQVRAAWKTNIKDSSGKPLY
>SEQF1516_EDU88360.1 outer membrane lipoprotein, Slp family [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDTHATPQNNGIELNRRDINIRQVYVTIRHIASESDENYKEISIMVLIFVDKDSNMNMTKGALILSLSFLLAACSSIPQN
IKGNNQPDIQKSFVAVHNQPGLYVGQQARFGGKVINVINGKTDTLLEIAVLPLDSYAKPDIEANYQGRLLARQSGFLDPV
NYRNHFVTILGTIQGEQPGFINKVPYNFLEVNMQGIQVWHLREVVNTTYNLWDYGYGAFWPEPGWGAPYYTNAVSQVTPE
LVK
>SEQF1516_EDU88361.1 glycerol-3-phosphate dehydrogenase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSASSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPH
IAFPMRFRLPHRPHLRPAWMIRIGLFMYDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVV
RKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYSWQARGLVNATGPWVKQFFDDGMHLPSPYGIRLIKGSHIVVPRVH
TQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYKGDPKAVKIEESEINYLLKVYNAHFKKQLSRDDIVWTYSGVRPLC
DDESDSPQAITRDYTLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIEGDRDDYAA
RLRRRYPFLTESLARHYARTYGSNSELLLGNAGAVSDLGEDFGHEFYETELKYLVDHEWVRRADDALWRRTKQGMWLNAD
QQSRVSQWLVEYTQQKLSLAS
>SEQF1516_EDU88362.1 putative membrane protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MDNKISTYSPAFSIVSWIALVGGIVTYLLGLWNAEMQLNEKGYYFAVLVLGLFSAASYQKTVRDKYEGIPTTSIYYMTCL
TVFIISVALLMVGLWNATLLLSEKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKETQVTQEEYSE
>SEQF1516_EDU88363.1 conserved hypothetical protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MSFRHVSFILLLTSQKYHGLFMKVFHNIFKYISSNHQDKHSDKVNNHQHHGKVDKKHRSEIVEIDKLDKHSQIDNDFGLH
IIYFLQHGCWNVTEHSPQIEKIWFYNSEPSIDIKEYNSFADNTTDTFIFTIIPDNNHVIKLSSPITVTIERKDGYYFINF
SGDKSDIIYKVDGFSIKERNFFTLLSGNFKPDWRWAVSKETFTKEKFDSYVESVFSKIDFYKQCGVINPQNANTAYFGDT
DGRVGAVLYALLVSGHIGIREKGWSLLCDLLKHEDMASFAYENKKLKKLFTLLDKRDMILNELHQHVFLKGDAITPCIFL
GDHTGDRFSTIFGDKYILTLLNSMRNMEGNKDSRINKNVVVLAGNHEINFNGNYSARLANHKLSSGDTYNLIKTLDVCNY
DSERHVLTSHHGIIRDEENKCYCLGALQVPFNQMKNPTDPEELAYIFNKKHKQHMDDHLFHLIRSNTMAPTPVYADYLNN
TTDFRPDPEDIFKCGQTLECGDPRKNIRQKYGHHGLGVNQNQQFDNGVMGLNSRMAVFDENKKIIGSSSGLSCFQPH
>SEQF1516_EDU88364.1 putative transcriptional accessory protein [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MMNDSFCRIIAGEIQARPEQVDAAVRLLDEGNTVPFIARYRKEITGGLDDTQLRNLETRLGYLRELEERRQAILKSISEQ
GKLTDDLANAINATLSKTELEDLYLPYKPKRRTRGQIAIEAGLEPLADLLWSDPSHTPEVAAAQYIDADKGVADTKAALD
GARYILMERFAEDAALLAKVRDYLWKNAHLVSTVVSGKEEEGAKFRDYFDHHEPLSTVPSHRALAMFRGRNEGVLQLSLN
ADPQFDEPPKESYCEQIIMDHLGLRLNNAPADSWRKGVVSWTWRIKVLMHLETELMGTVRERAENEAINVFARNLHDLLM
AAPAGLRATMGLDPGLRTGVKVAVVDATGKLVATDTIYPHTGQAAKAAMTVAALCEKHNVELVAIGNGTASRETERFYLD
VQKQFPKVTAQKVIVSEAGASVYSASELAAQEFPDLDVSLRGAVSIARRLQDPLAELVKIDPKSIGVGQYQHDVSQTQLA
RKLDAVVEDCVNAVGVDLNTASVPLLTRVAGLTRMMAQNIVAWRDENGQFQNRQQLLKVSRLGPKAFEQCAGFLRINHGD
NPLDASTVHPEAYPVVERILAATQQALKDLMGNSSELRNLKASDFTDEKFGVPTVTDIIKELEKPGRDPRPEFKTAQFAD
GVETMNDLQPGMILEGAVTNVTNFGAFVDIGVHQDGLVHISSLSNKFVEDPHTVVKAGDIVKVKVLEVDLQRKRIALTMR
LDEQPGETNSRRGGGNDRPQNNRPAAKPRGREAQPAGNSAMMDALAAAMGKKR
>SEQF1516_EDU88365.1 orotate phosphoribosyltransferase [Escherichia coli O157:H7 str. EC4501] [HMT-574 Escherichia coli O157:H7 str. EC4501] 
MKPYQRQFIEFALGKQVLKFGEFTLKSGRKSPYFFNAGLFNTGRDLALLGRFYAEALVDSGLEFDLLFGPAYKGIPIATT
TAVALAEHHDLDLPYCFNRKEAKDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERG
RGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV
