>SEQF2545_AGK83643.1 DNA-directed DNA replication initiator protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDAVGYEVFWNETLSQIRSESTEAEFNMWFAHLFFIASFENAIEIAVPSDFFRIQFSQKYQEKLERKFLELSGHPIKLLF
AVKKGTPHGNTAPPKHVHTYLEKNSPAEVPSKKSFHPDLNRDYTFENFVSGEETKFSHSAAISVSKNPGTSYNPLLIYGG
VGLGKTHLMQAIGHEIYKTTDLNVIYVTAENFGNEFISTLLNKKTQDFKKKYRYTADVLLIDDIHFFENKDGLQEELFYT
FNELFEKKKQIIFTCDRPVQELKNLSSRLRSRCSRGLSTDLNMPCFETRCAILIKKIQNYNSTYPHKAIHISDDVVRLVS
ENISSNIRDLEGALTKIIAFIEVSGSITIDIVPSLLKEFFLSARPKHITVETILHVVADHFNISYSDLKGKKRNKSVVYP
RQIAMFLSKELTELSTTELGIEFGGRDHSTVIYGCQKIEGEILTNPSLQANLDLLKSKVQDSIR
>SEQF2545_AGK83644.1 hypothetical protein TPFB_0001a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLISFRKASFSHRIFTVSFLLINLISIKNVVVSHNSNCEYLDKCLCLENYQTKTAHKLVKKVYFFSKKRGIFVSKV
>SEQF2545_AGK83645.1 DNA-directed DNA polymerase III beta subunit [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKILCEKEAFLKEISTAQEVISNKKNTSIFSNVLLAAQGALLTIRATDTKVTFETSIPVNVLAEGTTTVFCDKLVNVVSA
LPTKEIELTLCEEQLVITPPNKKISFQLRTLSHESFPCFPQNEGGVSLAVPTSDLRNMINHTVFAVSEDSTRHFINGVHV
DFQYGNIICVSTDGKRLAYIEKKGESSPQSFSGVIVPTKILGIVNRKLTPEGSVTLCITSQHVYFFFGGYKFSSVLIEGQ
FPNYKRVIPDHQERSFCVGRVELMEALKRVSLLVEQKSHRIFITIQQGLLTLSSKAHTQENEIGDAQEEIACAYTGESEV
IALNYLYLEEPLKVFTSKEVQVEFTDPAKALTLRAVPNTDCFHIIMPMQTE
>SEQF2545_AGK83646.1 recombination protein F [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLYQTRTAFTSLCLCKRSDSLPFLTVTAINFRNLAHHTIDISSPEVFFVGNNGQGKTNILEVLYLAAYGNSFRTRTESEL
YATHARSNEYRVKVMYRGEYTHTVQIFSKNGKKRIEKNLKKIRTKKELISSIPCILFFHNDLDFVVGTPERRRFFLDQSL
SMCNPLYLEYLQKYHALTKTKNREIKEKRVQLLDALDTQIATVGFDLVQWRTQLVRDFNVIFTKYYERLGDLAQVRIEYK
PSWSDSSVEEIVHSLYKRRKHDLAMGMSMSGPHRDKIHFTRSQALFIPQASTGQRRLVSLVLRMSQAVFYTGVTGKLPVL
LMDDVLLELDPEKRERFMMSLPPYDQLFCTFLPGEAYRRYGREKTRVYFVSEGACHE
>SEQF2545_AGK83647.1 hypothetical protein TPFB_0004 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNNGVNKLSDLLVLTTEYIQASYETEAFDAHREWVCIVGNPVALHSTLVDIRNGKVVVKVTHPGWAQYLLLKKDEIVHAL
RRRYPSLGVTGMSTYVDSTSRTPSAKKDMQGLSVSEKQTRPVPELAEVFEQLRTLFQVKTEEPSH
>SEQF2545_AGK83648.1 cDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEEISTPEGGVLVPISIETEVKRAYIDYSMSVIVSRALPDVRDGLKPVHRRILYAMEEKGLRFSGPTRKCAKIVGDVLGS
FHPHGDASVYDALVRLGQDFSLRYPVIHPQGNFGTIGGDPPAAYRYTEAKMARIAESMVEDIKKETVSFVPNFDDSDVEP
TVLPGRFPFLLANGSSGIAVGMTTNMPPHNLREIAAAISAYIENPNLSIQELCDCINGPDFPTGGIIFGKNGIRQSYETG
RGKIVVRARFTIETDSKGRDTIIFTEVPYQVNTTMLVMRIGELARAKVIEGIANVNDETSDRTGLRIVVELKKGTPAQVV
LNHLFAKTPLQSSFNVINLALVEGRPRMLTLKDLVRYFVEHRVDVVTRRAHFELRKAQERIHLVRALIRALDAIDKIITL
IRHSQNTELAKQRLREQFDFDNVQAQAIVDMQMKRLTGLEVESLRTELKDLTELISSLEELLTSPQKVLGVVKKETRDIA
DMFGDDRRTDIVSNEIEYLDVEDFIQKEEMVILISHLGYIKRVPVSAYRNQNRGGKGSSSANLAAHDFISQIFTASTHDY
VMFVTSRGRAYWLKVYGIPESGRANRGSHIKSLLMVATDEEITAIVSLREFSNKSYVFMATARGVVKKVTTDNFVNAKTR
GIIALKLSGGDTLVSAVLVQDEDEVMLITRQGKALRMSGREVREMGRNSSGVIGIKLTSEDLVAGVLRVSEQRKVLIMTE
NGYGKRVSFSEFSVHGRGTAGQKIYTQTDRKGAIIGALAVLDTDECMCITGQGKTIRVDVCAISVLGRGAQGVRVLDIEP
SDLVVGLSCVMQG
>SEQF2545_AGK83649.1 hypothetical protein TPFB_0005a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCNAGVMGSGVYFSVSGCVYVVSIVDNVRAEVDVSRETCGMRSGIKSTLILEDYLGSRSCKLYGGCVWGLVSDFPSAVLR
VYVYSH
>SEQF2545_AGK83650.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGTRVRFSFCGIAGVCLLALGFLVSCSLQSSRSATKKSEARRTSYRIGLMTSTGSQSVDDVLAKTRLVSIYGEARGETGG
RIVHVTYSDNFSHDHEATVSKLLALAEDSTIKAIVVSQAVPGVSKAFGIIKSKRPDVLLFAGEPLEPVEMLQESADIVVS
QDYLFGGYAVPWVAERMGARTLVHVSFPRHMSYPGLRVRRTVMRAACTDLGLSFAHEEAPDPVDGVSDGELEDFFHKTIV
KWIKKYGKETLFYCTNDAHNRPLISALLKYGGMLIGATIFDYADALGVHYAELEDVYKIREKVEKSLVAFGAEGRFGLNL
NAQAFTVTMGFVEYARKIIDGEPRKDDMREALAESFDLFTRDAHWRIAPYLRLKTHEIVPNHVLVYTDTYVLGKFTLPVT
DQVLPEGYWALTAKE
>SEQF2545_AGK83651.1 Tpr protein A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVKTRYTTVCMRLVLGSCIFILLLRGRATVSRLHASPAVTISGSTRLTWGINLGAKANFVPPVAPLGATGTVRENPNHRF
RHRRHGFRSSSTLFFSLTLCPPKTRSNLHKSSGVYAEILLRNLECALPLGSLSGEALGELTPTEKQSFSVEATLRFYGAY
LTIGKNPTFSKNFAKLWPPFITTRYKEADTQYAPGFGGYGGKIGYRVEDVGNSGLGFDFGFLSFASNGDWSTSGTSHSKY
GFGSDLSLWYKRNKKLFLTVELAGNATLQEGYATLAPTFSGAPNNKRASHALLWSVGGRLSIMPGAGFRFILATDAGNTY
RDTNSARARVVEQALELAEKTYPSLRTVRRIFSWMVQHVDSLGIDALVTAQWRWLSGGVYGATGAASVFGSGPFVKSTFQ
YTDFAAFLRLETRSGDDYTHALHGLNAGIEARVYLPLDYKSYLDNGGLPPDVVPAQGVAQQVANAARVGILGLLNFLNSA
TNFVARAAGLPADAIATGAASIALPIMGNAWVGYRIPCYDSMWIEPRAHIYMATNRFNFNGFKGTRNLKGELCFQYAVEL
RASPIKPVEFSVRWEQGLLSQDPYMLIEENWSWPGYTGSLFLGCKIT
>SEQF2545_AGK83652.1 Tpr protein B [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGACISVYARFALGCGVFFLHGAVLDGVSRAFSSSAAFSGSAELSWGVVFDAEGASPVTAGKSIRHGFRTKSSWKLAFPL
LPKKGATYTSFSGEDPIWVELSLKGLKVDFESALGSGTADPSMTTRSPFLKSGRSDFSLEATLHLYDVSFSVGKDPVFPS
NFAQLWTPFITTSYESRSVKYAPGFGGVGGKIAYQARNISNSGITFNCALSFSSNGIWKSAPSVTSKVKGKGTNSRRMPA
DPHSKYGLGTEFTLVYARKGREQVRLEAASCATLSAGYRTGPDQTHHQNKDTVLWNVGARLTLSPGAGFKIVCAFDAGTP
YKKGAARESLAETLAAQRGCNRFDTALMHALGLLVAAAKTRNELAAQMRSQSPPGVWEKFEQAVQSLPPITQGKPGVVGA
EVRPGTMWMELSPVRKALVDVLSVLEQGGFDRVAFDALLIVQWRWISLGAYVASAPTNVFGSMLFPRGSSDHFDCAAFVR
VESKWYDSLSKLVSGLSGGVEARLYIPFTHGLYLEPGSCTPNSTRGKKPQAFVLPPPGVVHPGAHSALPVVGKLWLNYRI
TLAAHAWIRPMVSLYGATYGAQGFSYGPGGAAGTVKRNRTFRAGKNLYYQVGVAVSPFERCELLIEWSQGMLARRPYISL
EHGSWPDKRSELVCSCKVLW
>SEQF2545_AGK83653.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKSQFLLKVWVVCVGALLCRCGGARAPQNTGGTKAVEDYHIGVMTGPGSHSSHDVVAAKRACAMYGAVGDGHRGCILHVT
YPEDFVNRQDETVSRLLAFADDPLMGAIVVSEGIHGTAEAFNKIRAKRSDIMLFVGDPHEYPELIQKSADIVVSDDYAFG
GYAIPWAAKKMGARTLVHVSFPRHLSKAELRTRRQVMEAVCADIGIEFASEEAPDPAGESGVEGARAFIGTHTKQWIGKY
GKNTMFFCTNDTHRVSLMRELVSKDGMLLGANVFDCAEALGVEYADDEDVSGILERVESAVEEKRLVGRFGVNVSSHIFV
STLGLTEYARRILQNELREKDMRVALSDAFSLFSKGTRWRVAPYTDLLTGKEVSNHVSVFSDIHILGKFSLPVTDQEFPE
KYRSIRFGRQ
>SEQF2545_AGK83654.1 phenylalanine--tRNA ligase, beta subunit [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPKISIHEALFFELLGERCDDDTLERRLRSAKAELECSSFSVREDKEGGSLSPGGEVCDPVQRTRGQASCVREGAFDARL
LKIELNDTNRPDLWSTAGLARLLRVHAGGASRAAQYRAFLSDRCTVRDSYGRCVVVDARLQTIRPFIAGFVARGTGLSEV
RLWDLIQTQERLASNFGRRRCTLSLGCYRAQDICWPLAYRAVLLAEVSFTPLGMSMPLSGEQILTQHPKGREYGHLLKDY
SFVPLLVDARGEVLSLIPITNSASLGAVVTGDTELFIECSGTDMCAVLVAVNSLACDLSDMGMQIEPVQITYSFDTPWGR
SVTTPFYFQEKREVAHEQIDRLLGMPLPVADITEAFARMDCAVQVKQGTYVVEPAAYRNDFLHAVDLIEEVMLGRTLDRF
SPQVPCSFTVGRLSDLTLLTRKIKHLLVGFGYQEMIFHYLGSAREFCTRMRCTADDLIEIENPLTESYRFVRRSIIPCLL
SAELKSAHALYPHRIFEIGKVAFCSPHGEHGTCTQQSLGFLNASQEASYNEVASLVSGLLYCLKLPYQVEEAQDPRFVLG
RQASICVHGSRVGIFGEIHPQVLSNWDIRMPCFAGELDVGALLP
>SEQF2545_AGK83655.1 S16 family endopeptidase La [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLGNLMLGPYCRSSLWRELSWQEVTGIVAPDTIAYLKARAQDHPFLLAHERACAAIRLGMRMYGDGYNICVIGASGTGKR
TTLQYLLKDFVPRPEQMWDIAYAYNFVHPHEPQVLQFPAGEGMPFATALRRSVNAILNTAQDIVKSDAFLRERRTLLADI
ETRECAELSRIEAELYTRGFRVRWHRKRGTYSFDLVPLLKGKDSSFEALHDLASRAKLSRCVVHELHARYRLSCDEVSSL
LHTLRTARRAARRRLAQYYRARLRLIILEQMACIKKRVACYAPVFSPPPVSCAAEQTEREKTSSSRLIEVPHEFEEMRAR
IISYIERIQTDVQVRVQCLMSMRISALVKKRFFDRYTLNFVCVHTEHAGYVFTEHQPNLANLCGSIESKGNEGDTLENGH
LRIRAGALHRAHAGVLIVQLEDLLAEEEAWTHLKRALRTKQVLLPAGSSQSQGMLRPEGVPLTCKLVLVGEPCSFERLSQ
EDSSFRELFKVCAEFDTSMPNSDKNQVALIAYLDRVVARYGTFSLDSSAYARLLAYAEELAESHTRLSTSFVQIADLVLE
SHAVAVDMHPDVSVITAHVVQEALNRRQYVCSRARERFRRMIACGELLVEVQGYRIGRINALAIEEHCGHSFGIVISLTA
QASAGKEGVMNIEREAGLSGEIYDKAHLIITSLLREKCLSAFADAAFDPAVDDLGKGQDSFPLCLSAALCFEQSYHGIDG
DSASAAEFLVLLSAIGRFPLRQDRAITGSVNQLGQVQAIGGVSEKISGFYDVCALNGLTGMQGVLIPKSSCAQLFLPERV
QDAVRAGTFHVWAVCTIDDALELMVPDDLKEQGSAQLYQCVRARLRDFYVTVKGHCE
>SEQF2545_AGK83656.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVARSIRVELESALDLLKQGDLRQAHQDLQDLLQKELDNRDVLYALTGIRFWEDRMQRVHTISGGLSQGEYLVGQWGAFV
AYMQKRGGVVEPVMYALRCCVFTYALRFYGSLITGDAREHPAEVYRKTGLCYKALGNYDAARECLEFAVSLEPDSSAILA
ELADAYALAGDERWSKLYFREALFKGASKLELNLLESDLIFSLIERVKSYGFSGVELLEWLPVYGTLEGVLTAKRELRAV
EIGKLKQAIYSLENDLRNEKVSAERRLLRPRLINHFFWLVDHYVNVQEDKRNIDEVLLKIKLLDEAVYHRYVRIA
>SEQF2545_AGK83657.1 transcription elongation factor GreA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSEHIEHDVREMLNEEKWTRATLTAYSAEKFKELDRIIAEAKRQSILDVLKGICDEHLAHSKNSIIALYISGIISLSKQL
LDDSCLVTLLTIFGDNHKNQIVEHLCTRVLEYGESKLALRALGECYKTSGNEQLYDVWERLVRIDYEEAEITRVLADKYE
QEGNKEKATEFYKKALYRFIARRQNAAIKEVWTKLVALIPDDVEFFYREQKKISEKLGEGRGSVLMQDVYVYYKENEDWT
TCINILKHILEHDEKDVWARKEIIENFRCKYRGHSQLEEYLKISNISQSWRNVFEAINDFEKHISFDEGSFVFHRTWGVG
RIAKVCNDELLIDFAKRRAHTMLLKMAISALQTLGKEHIWVLKSVLKRQDLAAKIKQDPEWALKVIITSFDNNCNLKKVK
QELVPSLLSVGEWTSWSTKARKILKESTGFAANPSNIDFYTVRSYPVSLEEKLAVEFKAQKNFFARIGILNTFMDKADTD
SDAFREMFDYFNTFLRAFSVVDGNVIAAYLVVTRVSTVLPHLNACRPHGFADLYAHIADPRLVYTEIKDKGLKWEFVNSV
KNFVSNWSDEYVKLFPEVLSLEILRALMEEGYKEKALRVVEACFEYYADNRAAVIWLFKTVRDEPWFQELRITAEQRIIV
LIHIVDITYREIANRRNTTENRKLNKQALSVLFGNDHLLEHFMLSHDVGTTTRLYTLISDIQGLDPKLKVHLRNKIIEKY
KDFKFFDTEERVVSGRGLVVTAKMLNAKKKELQDLLDVRIPENSREIGRALELGDLRENAEYKAAREEQTRLNNMVTRLQ
EEIERAQVFDPTTVVAGRVSFGTVISLKNHTSGEDETYTILGPWESAPERGIISYMSPLGSNLLNRKTGEQLAFTVGEHE
KVYEILSISAAEI
>SEQF2545_AGK83658.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRKCAMRIMRRLMLFLMCLCAALFAQELVREQSVTKSADITVLLDTSGTILPYRSVVSGSVLKDIATRFVRLGDSFHIIS
FSATPRHEISQVIRSEFDLSQVVSRFMILHQLGLYSDFLTALDFARTHLRALPAAHEKILIVVSDGIFNPPARSAYKNYN
KDQVKINLARAAADLRREQVRVFYIKLPFPQDIQIRDLDDNLLTDLQKTDDVQISAVGSFAEGQTRRPKLDTVGVVSDQT
GGVADNHAVATHGREDGTVQGVVGSHVEVARTQDRRSNADPAKREGVRPSSEATDVSREFTEDLGIRVSPVDSDGSVRFS
EKERTLPVLHFPRVLEVQGKYAECMFEVENSTDAPVLLHLERVIFDNGVETDIVSVQTESCAVASGARAMLRTTFLLPKR
YHEEGTYQVTMRVQFADNVRVFPQVATAELRVSPLPFLGLVRRGIHGVLSSVGLTHAFGYVLDMVGLSRTGFGAVLLPLF
ALAIFLVLVSAVVCRSKRVLSRKSWRGSPRTENGCQGPGSMSDFRAHSVKEQRQDQERVYAGMERIVSQRKSDVQDRLSV
LNAATAFGRDRVSFSPRVTRAEHGCSRSGMTEIFVFDQTRAIGKRNIHVMKAGTRLGVGGHKGDDFLIFLVPFPRRLAQV
YFDGEVYHLAILKPRYFPYEESSVVHDCVGRVVTLVSDRGYHVPFTFRQYEDPAVRLNNLLTSIEYA
>SEQF2545_AGK83659.1 hypothetical protein TPFB_0021 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDDARYAEWSASLVQLPDTHFFDLMRLYLGVLKTPFHKQRLVQQLSAFLQRKSIQNAVVQMLDELDLLFISVVMCVPRAT
LELLTIFF
>SEQF2545_AGK83660.1 hypothetical protein TPFB_0022 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPGEVTQAEVASVAQNGRVRQTPCYGINPLLQKALSTVAGLNLFLIPQKRMRPSAQLLTTDLMLCALYSFFTHGENLLKV
DGTFRKKAFVMFQALFPVDPDVVSVALPAYLQRAGEERGTSRLLQEGRRVLEHLGLIVCESAQVHVQDKRWASFFSLTAL
ERAVYLTVASTAILRKEVLVQRAQALRTLLCVLHPDAQYAPEDLTRVYRILVEEAAPSVAADFFSSLSLSKDTMLQKRKG
ALHDSSVFSMQSAITAIRTAQLFGLLCVKDGLCALNEALFKGQYTRGPGMVLSATAELTIFPDGDMQGVLPILSCAHVCS
LQTVATFELNKKSCTTGFARGLTVQALAQALECKTGEQVPQNILSSFRQWYAQITALTLRRGFVMQVDSSQQAFFESGGP
LHPLVRTRLAEGVYFFDECQECMLYQALARARLSYLCEPIDTATPLFRPGEQGARALHVPSFSFPVRSARGVSEESTRDF
AHLGAFVLETPNVSCTHSAADTPSISEQTGGVAHVQSEEDVDPSTSGATGKYWDKAQWRKVQRMRRAVRLQRLKEFEAHL
QQLKLDATEQTELRARLQRGLILDRMQLSSETIRRERTEASGVDFLGKYRLAECALRSGALLEIETSSGQSVHKIVGTVC
AIEKCEEDALLHVCVHAELPPERVSIARASRIVLLKNSIFS
>SEQF2545_AGK83661.1 NSS family putative amino acid:sodium (Na+) symporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRRKQGRELFNSHVGVVLSCVGAAMGLANVWLFPGRLVEFGGVTFLIPYFIFLFGLSRFGLMGEYAFGKTLRCGPVRAF
TRVCETHPSCFLRALRGSGWFPVGVLLATCSFYVVIIGWILRYVVFSCTNALAGTQAHDLFYQVAGTSANVPWTLAAIAL
TACVVSAGVQKGVERGNIIMMVLFYGVLAFITGYIFTLPNAWIGMRRMLAFQSSSLCNPRLWLYALGMSFFSLSLGGAAM
VLYGSYMPDTVDIPRTAFQTATLDFLASGMSALCLIPSAWVLGMDVSSGPEFLFVTITRVASQIPMGVMISVLFFLCVLC
AALSSAIAMLEVILESFVHTCTVGRRTLTWSLALVVAFVSLPLNASMRVFETFTDIVVVILSPLSALMGSVMIFWVYGAE
RCRVAINRCARGPLGKWFTPYMRYVYLGLCVMIMVLGVMFGGF
>SEQF2545_AGK83662.1 Trk family potassium (K+) transporter, NAD+ binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRFALIGLGDFGLSMLKELLKLTNNIVLLDRDRTLVETYRSRVRIVRAIDVLDEFTLCKMIPQDINAAVIDLGVKIESS
IMITTFLKKLEIADIVVKAYSAEQGHILSSVGATHVVLPDREAAKKVTPMIAFDLLFNFMPLSAQLAIAEMAVHEDYVGR
TLREVDVRKNFSLNIIAIRKRDAEDFCFINDPEYCFEANDVLLVAGSHKDIYAQSQDKLAHTHSFSDFFKQWFLTS
>SEQF2545_AGK83663.1 M16C subfamily peptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSTLLHGFEIIWRHSLAELSAVGVYARHKKTGLELYHILNEDPENLFAFCFMTAEEASTGVAHILEHSVLCGSQHYPLKD
PFLILAKQSVKTFLNALTFPDKTVYPASSLVETDYFNVMSVYADAVFFPLIEEWTFKQEGHRFEFNEHNQLTLQGVVLNE
MRGVYADFHTLVYKHATHATTRGSVYAHDSGGHPTVIPRLTYESFKAFHKKHYHPSNCKLFLYGNIPTEKQMAFIEDKCL
SKFSARKALPPIPPIPAYQSPRTYTGYAPASEGMDLTRCAVLLSWLLPESDKAEQLMDVFLLEHVLLGHDAAPLAQALLE
SELGEDLYAYNGSHIDLKRMLFFVGMTGVQHTQVDALKACVFETLESLVAHGIPPQEVETALNALEFSNTEVRRSDGPFS
LVLMQRSLRGWLHGAGPESSLRYIPALQALREKVHHHPHYVENLILTHLLRNPQYTVLSVHPDPDFSKKLDEQLEKYVQD
FSRTLTQPAAARLRADQESLRVRQTTPDPEELLALLPHIKREQLPVPTPELSETMQFFGSVPVLVHELATNDITYLHLAI
PADMLSVKEAQLLPLYGYALTGMGTETHHWSVVSAEIARLTGGFAARCIVAGDQGSEILPLLRGQNTLQRSDIVGRAWLV
VSVKMLSRFIVQAISYVCAHVRSLSFTDTRRLKDILAQYKNDLDSAAMHSGHSIALAKANARVNAAKAVEELWTGVTQIR
LVRALWTECTETVASPSLAAKLKALHEKLLTAGVIGCVCGTETSLHTALDALAKPLACFRAPLSTYFIHHTSAPTAHEQQ
IPSAHGVLFQEALQHMRTRNMLTLLPAPVQVGFAALSLAHPRLPLERRGVEQVFARYLSTEPFWEKIRTIGGAYGAFTLP
DPVHGIFSSLTYRDPNPLHSLDVIFKTIEHLHADHKGTSSLFNQKTMERLIIGAYSTAVTPETPEHKSFASFLRFLNGTT
ETERIAAIEHILDARVTDMHLCTQLLWAQRTCAEAAVVSTATSIREAATLEPYFSKLEAEPPL
>SEQF2545_AGK83664.1 flagellar motor switch protein FliG [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNRTESPRGLIKATVREQDRGRTVYKKIAQFLSLIGEEQAALVLKQLEPAQIEAVVAELLTLKPLSPEEAREILREFSAL
CARVSPVTGGLRAAQSMLSKAFGEEKADLILKRAVPAAQPKPFEFLAALEASQLLPLLEGELPATKTLILSQLPPESAAH
YLSNISTEEKKDLIVRLAKLKHVNPQVLQVMSDSLHKKFAALHLSQRRDLDGHAVLAAILKKMERATEHSILHALAEKNP
TLAARVRTHLFTLDDIPALPDTFLQKHLASCSEKTLAALINTNHPAFVQKILSNLSKNRAQLVRDEYDTFPPSAHDTRTI
TEHFLATLRSAGAQQHIASK
>SEQF2545_AGK83665.1 putative hemolysin HlyC [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSTLKGALQRGGVQGCMALSLRFWCFSPSGELRVSVLSVSAAFGVLVVLLVLSMLFSAAETAFCALNTLRLRYLYEKRHA
RARVAMRILRRKNFYLAAVVIGNTLASSALSAVIALFARALFGIHAVGWSIGAGTVLTLLFGEIIPKSLALCRPNAVALH
TARFLQWSALMLTPFVQVFCMARSALLRLARVACHTPSLRVTDDDLHTVLYAGEADGTVTSRERALYQRILHSASLTARD
IMTCRAQLIAVPRASSLAEAIACAQKMRVSRVPVYERSVDWIIGIFDVKKFLCSEEVDGRDLEECGTLMQHVSAPVFVFE
CTRLAYVQHKLRAHSRAVAIVLDEYGGTAGLVTKHNIYQAFFKSSAHEFPVNSTGPQVTRAGVRAYIFPGSLRLDEINDL
LGTDFSSCTSETLAGLIMEYTGCIPDPGTTVVFGSWRCVVLQLHVRRIVRVRFEFQG
>SEQF2545_AGK83666.1 putative hemolysin HlyC [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAYPFLVGLELMFLLVCSALCAGSESALSSVNQDDERKLKRHSTRCTQRLCWLLARREQLITTVIVQNTALNMVLSSVVT
LGSMELWGAQSVWKALVAVTCVIILCGEMFPKALGARYSLGFLMWIAPFLQLSYWLLYPCACVSSALMHVLEGIFLPRHT
TCLSREEIKTLIAVGAREGVISSTENQLFQRALQFKRIPLAHVMVPHTHFVSVFQDTPLSHVWDAFRTCSFSQLLVHDAA
GIVWGFVHYWDIFGESKVLPSQSSDQMVSACVANTRAAVHRVGDLAQELCCVPNVADLFSVLDMLSVSKQQMALVVDERG
DGEGLVTMTDIMEVIFGSLAGVSEGVEGYTVHGSMVQRMSKPRVDFQMKSVGTHEILCSGTVPLEYFNEVLGTRLQSRVY
HTVGGLLLERFGRLPTVGDELVIEGLRFKIRRVLDRYVVSALVDTRACRSSVG
>SEQF2545_AGK83667.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGPYFCGIRAIKLYVDRCSTGMCAQRGESMSCYRVEGGFPVSGCIRVCGNKNAALPCIAAAVLTQEPVLLQNVPDIEDVA
VMLTIFRAFGGSVERRGNHEYMLHLPQLQTCEVPCEAAQKVRASILFAGPLLARGRKAVLPPPGGDVIGRRRLDTHFLAL
AALGAQVRLDGVFTFSANKLVGCDVFLDEASVTATENVLMASVLAEGVTVITNAASEPHVQDLCHLLNAMGARVSGIGSN
VLTIEGVSALHGTTYTLGADFMEVGSLIGLAVVTRGALTISDVNVRDLRPLGFAFKKLGVIWSEQEHAVSVSASQDLRVN
YDFGGMIPKIDDGPWPAFPPDLTSIMTVVATQVEGVILIHEKMFESRMFFVDKLITMGARIILCDPHRALVSGPSALHGS
DLVSPDVRAGMAMVLAACCARGVSIIRNVYQIERGYERLVERLQAIGVRIWKES
>SEQF2545_AGK83668.1 chaperone GroEL [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKQLLFNEEARKKLLSGVEQISSAVKVTLGPKGRNVLLEKGYGAPTVTKDGVSVAKEVELEDPFENMGAQLLKEVATKT
NDVAGDGTTTATVLAYSMVREGLKAVAAGMTPLELKRGMDKAVAIAVDDIKQNSKGIKSNEEVAHVASVSANNDKEIGRI
LASAIEKVGNDGVIDVDEAQTMETVTEFVEGMQFDRGYISSYFVTDRDRMETVYENPYILIYDKSISTMKDLLPLLEKIA
QTGRPLLIIAEDVEGEALATLVVNSLRGTLKTCAVKAPGFGDRRKEMLEDIAILSGGQVISEDLGLKLESADIALLGQAK
SVKVDKENTTIIDGSGKSKDIKDRIEQIKKQIEASTSDYDSEKLKERLAKLSGGVAVIKIGAVTEVEMKEKKHRVEDALN
ATRAAIEEGIVAGGGLALIQAAAALEKADLSGLTPDEAVGFKIVRRALEEPIRQISENAGIDGAVVAEKAKEKRGIGFDA
SKMEWVDMIKVGIIDPAKVTRSALQNAASVSGLLLTTECAIAAIPEKSSSTPPAPDMGGMGGMY
>SEQF2545_AGK83669.1 hypothetical protein TPFB_0031 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDLGQRVVRVIPLAPLPVRVYNAGGLRVDFFPRFFGRSPQGVGVGFSRLKLSASVGSNGFRLTRAVWIFWLCFLVSGLSR
AFLVYFLSVIRI
>SEQF2545_AGK83670.1 hypothetical protein TPFB_0032 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNIVLFEQEEVVHGCAVLSFRDSRFCHIKRVLKLSAGACFKAGIINGVKGSARISLATEKYLVAVFEKLEYEDCALFPLH
LVIGFPRPIQLRRILRDVSSLGISSIHLVGTELGERSYLDSGLAHMEKMHTYLIRGLEQAGGTKLPLITVSESVRTFCSQ
HTHILGDSTHQKLILDTKNTLTDLGSAALRGDVLWIAIGSERGWTESERLLFSAMGFRAVDMGRRTLRTETAACAACAVV
LANAHAWKRKIPRPGKRSSPISRKNP
>SEQF2545_AGK83671.1 hypothetical protein TPFB_0033 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYSCLRRLFGIRGTGTLCAMSVFCLLLSFGRRCVAADNFLSFLVWNLVLAFIPWLISAILHVRRFAVRSVQLFLMLLWLL
FFPNAPYILTDIIHLGKGKSFLLYYDLIILLAYSFTGLFYAFVSLHLIESILARDFHIKRPFIISVFELYLCAFGIYLGR
FLRWNSWDIVLHGRTILSDIGIRVIRPVFYVDTWMFVFFFGTMLVLCYQSYRSFLTHTRNDK
>SEQF2545_AGK83672.1 zinc (Zn2+) ABC superfamily ATP binding cassettetransporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNATLLSLRKKRPQLHNANCLSTMVFEEIPVQHPKKELHILQRVCEYAPVWGGSPFKGAIMQRCSVVAALAGVVFLAQAC
SLSTPSRITHTDKLPVVVTFNALKELTQMVGGEKIHLVSIVPDGVDSHDFEPKAKHMAFISDAKVIVYNGLGMEPWIHSV
LHAARNSGSIRVEAAQGIVPLKAHTRGHTAHHVHAHASHGSAYDPHVWLSVCNAQTMLRTIGKALCKADPQHTRFYKRNA
RNAAARLEALYKEYRSKFAALSHRYFVTTHAAFGYLCRDFDLQQKSIKDVFNTEEPSIKRLVELVEFSKKHSVRTIFSER
GPSEKVARVLAQEIGASVETIYTMEKNEENLSYYERMKHNINRIYRACSKQVTPSQ
>SEQF2545_AGK83673.1 zinc (Zn2+) ABC superfamily ATP binding cassettetransporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRIMASPFAVLLQNVSFRYTADARFILHEVDLAIPKGAYLSVVGENGSGKSTLVKLVLKLLKPSTGTIAHFVQRVGSVPQ
TKMHTLYFPLTVYEMLNSYRRLLRISHKWVVDAVLEEVGMRGAKKKLVYTLSGGELQKVYIARSLIGDPDLLVLDELSTG
IDSRGQKDIYALLKGLNTSRNVTVISVEHNLDAAITNSTQIFHLSEGHGHLCNPQQYVSEFLDMQKKDALACAQCRSR
>SEQF2545_AGK83674.1 zinc (Zn2+) ABC superfamily ATP binding cassettetransporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLQYAFMRNAFVASFLIALLCPLVGMHLVLRRYALMGDALAHGSLAGVSIAVSCGIHPGWGSFFFTALVGVLIEFLRAFF
KNHHDLILSIVLSLSVGIAVTLLSSGLIQADIDSYLFGSILVVSTRDLWIMLALSVFCVGTLALRYHQLLYLAFDEETAR
ICGVAADGINYVASVVISATIAASIKITGILVLSSLMTVPVATALQLRVGFLLTLVAAFLFSMLDTALGLVFSYYLNVAP
GGFTALVSVVVLMLVIALTQVGRART
>SEQF2545_AGK83675.1 D-lactate dehydrogenase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRCVVFNLREEEAPYVEKWKQSHPGVVVDTYEEPLTAKNKELLKGYEGLVVMQFLAMEDEVYDYMGACKLKVLSTRTAGF
DMYNATLLKKHGIRLTNVPSYSPNAIGEYALAAALQLTRHAREIETFVRKRDFRWQKPILSKELRCSRVGILGTGRIGQA
AARLFKGVGAQVVGFDPYPNDAAKEWLTYVSMDELLSTSDVISLHMPATKDSHHLINAKTIAQMKDGVYLVNTARGAVID
SQALLDSLDKGKIAGAALDAYEFEGPYIPKDNGNNPITDTVYARLVAHERIIYTPHIAFYTETAIENMVFNSLDACTTVL
RGEPCAAEIKL
>SEQF2545_AGK83676.1 putative regulatory protein PfoR [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHTQSLSPRQFMMKILNGSSAGIVIGLVPPAIAGELFRALAPLSPLFAALYHVVLPIQFSVPALIGTLVGLQFHCSAPEV
ATLAFVSVIASGNVTLQNGAWLITGIGDVINVMLISALAIILVRALRGKLGSLTIIALPVIVAVVAGGVGSFSLPYVKMI
TFFVGRVIATFIALQPLLMSILLSMSFSLIIISPVSSVAVGIAVGLTGLASGAANIGVSSCAMTLIVGTMRVNKIGVPLA
MFAGAMKMLMPNWIRYPILNIPLLLNGLVCGVLAWLFNLQGTPASAGFGFIGLVGPINAYRLMAYTPMVRAGILFLVYFV
LSFLAAYLIDFILVDRLKLYRRELFIPEQG
>SEQF2545_AGK83677.1 hypothetical protein TPFB_0039 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARTAASVRQENKPCQQFYFVLDEKALQSPLRENPSKNVRTIPDAGDENSSFGHARVIA
>SEQF2545_AGK83678.1 putative methyl-accepting chemotaxis protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDVSRIVRGVKYRAITYSYVFAFALSAAVSHTALPAPPSAENGVLDLRQWDFSSGDALLSLSGTWGFHWNELLTHSAEQP
AAFMTVPSLWTKPRGAVQIPAIQAYPHYGCATYTLKILLPPRAPSLALSCDTLNYAARIYANGHLLTELGTVARNRADAV
PYVHPAEVWLPTHEPEIDVCIQVSNYHSLRPGIVGEVHLGSVSRVRTRVLRKDVLEAMTIGFAFTIFAYYLAMFCFRRLS
SCSRKSYAENERADTAGVLGVSEKSLYACSLFSLLIVVRLLLTGNAFLPRLITIGWDPMVRLEYLTLAFSGVSCLYYLST
LYPGLVNQSFVVAFGAEGLAYAVIILLLPPASFARLLPLQQLFVLLLLGIVLWVMCKVLYRKKRGAVPLSMGVLVLGVTA
LHDVLLAVGVLSGAPLLIFGFVGFLVTQTALIEWQVVLDGRTAQRLSQDLSSSSQRLERLFGEVRRTAQELSHNEQNLTE
TMDRAEQVVQDLTRYTGAVREELAVQGEGFSQTRVVNEELGSSLRELDEQMEAQGERAREALEAVERLGSTVHNLRGKFS
AVHADFEAITTASKTGKECVGRMMEVIEEITSRSRGLAVTNALVVDISGRTNLLAMNAAIEAAHAGDAGRGFAVVAGEIR
SLAARTAAESGATGKMLKEIEAVIGESGHASAGVAQSFTDIRGKVDGFSTILADISGAVQVVGEENERTVERMRTVTGQL
CTAREQGKVIAEVCTRGAAHAERLTRDAQKVCAEVETMIGNVEVLTEVVARTRAVELHTREVIARLSGLLDSNIPTDEPQ
SEYRHGGGGG
>SEQF2545_AGK83679.1 LysM domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSQEIGIKLADGSFFPLFTAEGAQRTTLELVTANDQQSRALLSFFKRVSPGDGEASVTSAELEPMGALSIDTLSVAAAGG
ATIRLEVECDGSRCRARATDVGSGAFQETSFSVLERSSGDATPDEQPAAQIEHVSSFPEDEGGDGSTLTRRRRILLAVCA
FLILLGGVLVGWVLYMHGASRPAVVPSQKVELPRSSAHVAARELERTAVEARVVDLPSETALPETHKEKDVPPASPGAET
ATSAAAEPVEESGSGSVKVVRYTVKRGDTLWDLARSYYKTPWRYMRIAEFNRLKNPDHIVAGTSIEIPSR
>SEQF2545_AGK83680.1 putative lytic transglycosylase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKFRHGKHLVWGGGFFSLLREGRLCLRVWCVVCVLVSWEGTVCARGAREVDIPQFLRDKNYTPFLKPTDEFLEQVAAREG
ASYFIGLHLKRAKFSEEAHEYFVRGAAQAAPYRQLCAHEAHNTGSPLQRLAFIEKQLHVLNAGSDAQTKTQQQTLRLLRS
RVLFELERYYSLRTVVESWYNDRALAPHTSAQFAALIAALPDLPRIFKEVHGARVDVFHRNYKRGWERVRLLLRSSAWHT
RYATNSVLSDFGKAALYGSENSVKAAQVFLDHLAHLSRSTLSNAELEARLRFYCYFYAARLYSRSASHKKQALPLFKKAE
KVATRRQDADNALWYYLDVLRALDFDSFFKVLVESAPRWRSDSWFSDLVDYAIVQLTTQQDWGRLATLQEVLTHRALPER
SARVTYVLARSGTLSEESARRAYRTIFETAHSSLYYRVLAACALGIPLEEALYKVRSKRTPHPFLTPDESRAILQGYVDY
HLDDMFYQAMVQFYPDIPLHLAEHFANAHIQRSRWSDAVRIQSYAIRSHGARYSVEHLKIAYPRPWLDVIQGYAGKYHIE
EYLLFALIRSESLFQPQVISRAGAVGLAQLMRPTASDIARKLNIDTYDLTDPDINVRFGSLFFSDLIRRFDGSVFCALFS
YNAGPSRVRKWKKQRGSLPDDLFLETLPLAEPREYGRKILSAAVMYGYLYYQKQASDVVCALLPEFCRAS
>SEQF2545_AGK83681.1 glucose-inhibited division protein A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGFRFSDYDVIVVGGGHAGAEAALAAARMGEHTLLITQTIDSIGRLSCNPSIGGISKGNIVREIDALGGEMGKFADACMI
QYRLLNKSRGPAVQAPRIQADKFLYAQKVKYTLECTQHLHLYQDTVVDVVCSNTTDAGYVAYGAAHAVVTARGRRISARA
VVLTTGTFMEGRVYIGEYEAPEGRLGEHAAEGLGAALRKKGFQMGRLKTGTPARVLRKSVDLSVMEKQEADAIMRPFSFA
HVEINRPHADCYINYTNERTHQLIRENFHRSPFFSGRIKAVGTRYCPSIEDKVRKFPDRIRHQLYIEPEGLDTEELYING
LSSCLPEDIQDEMIRTIPGMERAVITRPAYAVDYAVLFPVQLGIDLQTKRVSGLFSAGQINGTSGYEEAGGQGIIAGINA
ALYARSTKTKEEYHPFVLKRDEAYIGVMIDDLVTQGIDEPYRMFTARAEYRLKLRHDTADERLTEKAYAIGLQKKSAVET
LQKKMRTKHEILHLLQTNKVSLTHANAYVQLKPHIGKSFAATLRDPVIPLGLIASLNEQIAQFPLEVFQSVGVEIRYEHY
IAAQDQRIAQVEKMEGIKIPAHFDYARISGLSVESRTRLEHVRPDTIGQVGRMRGIRPSDVMLLLAHLKR
>SEQF2545_AGK83682.1 adenosine deaminase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKSLEYYRSQPKADVHTHLNLSMKYERYKQWSGVVIPNFPRKMRGLDEMHEIIGEYTRPQCKTAQDVLNLFTMSIEDAIA
DNVVVMETSVDIGFITHYEENLDHFLCDLSDLHRRYKRNVTLHFELGISKIRERSFVEQWAEPMMRSGIFENIDLYGPEI
SEGIEDFIYIFKLAEKYHLKKKAHVGEFSDAQSVRHFVEIFNLDEVQHGIGAATDENVLRFLAERKVRCNVCPTSNVMLN
AVECLEKHPIKKMMDAGVRVGLGTDDLLFFGKTNSEQLFDMVSCGLITELHAEALLAVR
>SEQF2545_AGK83683.1 hypothetical protein TPFB_0045a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSSNAMLLTGILVSYIQWRLIKNQVLPNVLHLRKFPRGGGLSNGIGQGNLRVCSIRRDKDNQQHEQINVPLLTNPTTLTS
VVHANTLHM
>SEQF2545_AGK83684.1 PSP1 domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIPKLSPNADPCTACASTPAFPPQPMEEEGEFLYQLRLEYSREVLYARFHAALRVHTFVVVPTRYGNDIARCVGRIRTPV
QTDIASVVRVASDQDLCTWHIHREKERAAEMIFRDRIEHYQLEMKCICCHYPLEEARVVFLYSAPARVDFRELVRDLGAT
FGTRVELRQINEREEARIVGGIDCCGRALCCCSVFSRLRPVSVKMVKEKNLLFRSTQMMGRCGRLRCCLTFEE
>SEQF2545_AGK83685.1 hypothetical protein TPFB_0047 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGYRVGNSDSTSLLSAFAPPERAKKKSKEKRPLQAARFLSLLYPKTDPHSAVQDPSLVHEEHQTRLAYLQDRLCSTGDIL
KNTRTLETIAAYKQAVKEFVQYAIKHNYTTESKSSIRIDRGTGMPDTVIFTKIKVIDQKLASFVRELMSHQVDQLTVLQK
TEEIYGMLVDLLI
>SEQF2545_AGK83686.1 hypothetical protein TPFB_0048 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKIERRSMNTLIGAGSRISGNVVVPGSVRIEGDVDGDVITTGHVVIGKRARVRGVIRVGSIIVGGMVEGDIVASEAVQV
LPSGVILGAVLTRKIVVDEQAFLDGFCYAVADQEGFNKVLKAYLGRKSIHTSAFGYNKYSKSG
>SEQF2545_AGK83687.1 M23B subfamily peptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARIRRYKRIEYAFVRFCIDRCTRCARLVREAAARLGAAGRAELTVMLVPHSQCAARTFCTTARTLLCVLLCGVGVLASF
FWFAHQSVTSARRLAAVRAEVDRTQVHLALLRQEAAELIRTSKAFQTSLSQTFSQVGLSGLQSGAEKPVRSVSDTNQSNE
PDDASAKDGAQKGNVGVTEQHGKNAQGVGSEPEELRRIAAYFQNSVQPVREIGKLLNSQTALFSDIPSLWPIKGGVGHIS
MAFGKNRHPFTGQWYVHKGIDLSTHRSGDPIVATADGHVVTVEYDSGWGNYVIIKHKHGFYTRYAHMQSYTVTRGQHIRQ
GQIIGYIGATGVATGPHLHYEIHIGSDVVDPGKYLNVKTAGAG
>SEQF2545_AGK83688.1 putative phosphoribosyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKRFIPYNVIRDEGFGMARRIVADRFVPTVMYVPIRGGVYLGNVLNEYLTIAYKAEPPILYAAVVAHSHCDLRKRRVIS
VDGWTYPPEYLRVGDKVLIVDDIFDSGATINYIASLLMQKGLARGDIRVAVFNYKVFVGEKQPPVLPDYWCIKHEVRSEA
DNEWFHYMSHELSGLTAAELEQYYYAQNPALRKTLADINNQL
>SEQF2545_AGK83689.1 peptide chain release factor RF1 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIEKLEELRAQWRKLQQEVENPSLFSSTQSYRERMRDHAYLSRLMEEYDRYLLTEKQLEDAHVLIQDESDADFKDVIRQE
IRTLEAALHTSQKRLKTLLIPPDPLQEKNIIMEIRGGTGGDEAALFAADLFRMYTHYAESKQWRYEVLAVSETELGGFKE
ITFSISGRDVYGSLRYESGVHRVQRVPSTEASGRIHTSAVTVAVLPEMEETEVDIRAEDVRVDVMRASGPGGQCVNTTDS
AVRLTHLPTGIVVVCQDEKSQIKNKAKAMRVLRSRVYDLEESKRQVARARERKSQVGSGDRSERIRTYNFPQNRVTDHRV
RVTLYKLDAVMQGALDDIIEPLCIASRESVI
>SEQF2545_AGK83690.1 HemK family methyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQELCTIRQARMYARALFQDAPCLRGQNTPLLDADLILSKLLAKPRAWILAHQQDEIASVAHEFKRLVHLRCRGRALAYL
TREKEFFGLRFRVTRATLIPKPDTELLVESVLAHVASQMMKPRSVSVHKDTSALPVLKIFEACTGCGCIAIALMHMLRAR
GTPPLYVIASDICMRALAVARYNARRLLDVSANSRVRFVHADVRAPIPFFSPSEGTDVVQERGVCVPYDVICANPPYVPS
AQARALLQDGRGEPLGALDGGADGLDLVRAFAHHSAAALKEGGCVFCEVGSNHAQRAARIFQAAGFATVKISKDLSGKER
LISGILRSQSRAVTAPSG
>SEQF2545_AGK83691.1 ribonucleoside-diphosphate reductase subunit beta [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMESSTILQRRALFNEAGDIELHKRRMVGGNTTNLNDFNNMKYPWVSEWYRQAMNNFWIPEEINMSSDVQDYRNLSAIEK
TAYDKILSFLIFLDSIQTANLPNIGQYITANEINLCLTIQAFQEAVHSQSYSYMLDTICSPEERNDILYQWKDDEHLLAR
NKFIGNLYNEFQDDKSVLALLKVAIANYVLEGIYFYSGFMFFYNLGRNNKMPGSVQEIRYINRDENTHLWLFRSIIQELQ
KEEPQVFTARNVRLFRDMIREGCEQEIKWGDYVIGDQIPGLNRHMVADYIRYLGNLRCENLGFEPLYEGHRVEPESMSWV
SQYSNANLIKTDFFEAKSTAYAKSSAMVDDL
>SEQF2545_AGK83692.1 putative rRNA (adenosine-2'-O-)-methyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLEHMKHEQARSQLSHEPPKRRRASLTVCGLRAVETLGSIHPEKIHRFFFTPVRAKRFGPLCAYLAARKRLYRSANTQEL
ERLTQSVHHQGVAATIDEPRFPAVTHSQVEFWVQRREFVVLLDRVGDAHNLGAIIRSAAFFGVHSLVVSDCRQQAQVTSA
TYRVAQGGMEFVQLLRCTNAQEVLEMCAGKMTRVGASPHAFRSLTRLSNILSPEEAVILVLGNEETGLSEHLTAHCDHLC
RIAGSGQVESLNVAQAGALFLSTIVQLRQSPQDYTQGHRATPRAQERVHRCGQLEEKGQKNGARVLIPRSGARANSRES
>SEQF2545_AGK83693.1 hypothetical protein TPFB_0054a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRYGTYSAIGFAVRVDVRPRVPLRTQPALLSRRKTCKELAQSVFFFYPRPRSPEFIT
>SEQF2545_AGK83694.1 oxaloacetate decarboxylase subunit gamma [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNQIRLFAQSALVSVMGMGMVFAFLLLLICVVRCVGALVSSFGWDRGPDEGVGAAVPAGGALAAAIAVAVHEKARSTS
>SEQF2545_AGK83695.1 oxaloacetate decarboxylase subunit alpha [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSTPVRISEMVLRDAHQSLHATRMTTEDMLPICDKLDRVGYWSLEAWGGATYDACIRFLNEDPWERLRALKARLPKTPIM
MLLRGQNLLGYRHYADDVVDAFVEAAARNGVDVFRIFDALNDPRNLSQAARAAKKTGKHVQMAISYATTPYHTAEKYVEL
AKEYARFGADSICIKDMSGLLTPYGAYDLVSAIKKSVDLPVELHTHATTGMSVATLVKAAEAGVDVIDTAIASMSMGTSH
SPTETLVEILRHTGRDSGLDINLLLEIAAYFRQVRKCYAQFESSFLGADTRILVSQVPGGMLSNLENQLREQGALDKMDQ
VLKEIPLVQKDCGYIPLVTPTSQIVGTQSVLNVLFGRYHRLTAETRRLLTGQYGRTPASCDAGLVERALKEEKLSQSLVC
RPADALPHELDRMRSEARAAGAQDTIEDVLTYAMFPKIAPTFFASRAQGPISFRGKGQGQKQKGESAGSVASYVATVNGT
AYTVVQEGAVLRVNGTPYTVRVEAGPSVASGTSQGTVTTAKVGACTTLPAPVAGSVVKHTVQDGATVNSGETVLMVESMK
MELEVKATAAGTIHFLIAPGAHVSAGQVLAEIR
>SEQF2545_AGK83696.1 oxaloacetate decarboxylase subunit beta [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNTRLPLRVLQCVLVGLLVCGPLCAATRRPVRASAPVPMVQSCKDTGARCAPASSMREDMRASHGAAPLLSVRKFLLNTW
HSTGLYAFFHGVTQVPDLANPQRTHSVFGYQQALLLVVGLLIIYLGAAKGFEPLLLIPIGFGTVFVNIPGAGMYSEHGML
KLIYDAGVGNEFFPMLIFMGIGALTDFGPLIANPKMAVLGAAAQLGVFLTLFGVAALNFVPGIRYSILDACAIAIIGGAD
GPTSIYVSAKLAPELMAVIAVAAYSYMALVPIIQPPLMRLLTTRKERLIRMKQLRPVSRIERVLFPLVLLLLSVLLIPAA
SPLIGMIAFGNFVKECGVVERLSKTMANELLNIVSILLSLGVGSQMTPDKIMNPNALGIIVLGLVAFSVATAGGVFMAKL
MNLFLSEKINPLIGSAGVSAVPMAARVSNKVGLEEDPSNFLLMHAMGPNVAGVIGTAIAAGVFISAYGG
>SEQF2545_AGK83697.1 replicative DNA helicase DnaB [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPGMPNPTQELKGKIPPHNLEAERAVLGAVLLDDSALSTATEQLSASSFYSAAHQRIFQALVELSDLGQRPDILVLSEHL
RSCEALDFVGGSAYVASLTDAVPSAANVEYYTRIVCDAAMRRSLLKVARIITAEAFNDTVSGNIVLETAQREIYDLTNAR
RVATFKLLKNLIPDLVNTIETRYRNQSDLVGIATGLTALDNLTGGFQNSELIVIGARPSMGKTALAMTMASNIAIRQRIP
TAFFSLEMSNLLLMQRLIAAESGVSATNLRKGLLQLSDFGRIQNAAGEMYDAPLYIVDVPNMKLLDLRAVARRLCVQEKI
QIIFVDYLGLIVADNPFAPRYEQFAAISQSLKSLARELDIPIVALSQVGRPAEGSAPNLADIRGSGAIEQDADVVMFLHR
DRNETETQLILAKQRNGPIGTVELEFQASFTRFVCKSP
>SEQF2545_AGK83698.1 hypothetical protein TPFB_0059 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRKYLSARSMCCSFFSCAKNCATLGLDSTEGRQFLAVGPQPFASLEGFHGEGGDCLFTTFPPLSIPRRRFCAGHA
>SEQF2545_AGK83699.1 ribosomal protein L9 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKIILNQDVKILGEEGDVKEVAAGYFRNYLYPRNLAVPHNRFTVARFKQRQQDIEMRKSLKRQDAANLKARLEAQPVVIA
MPAGTNGKLYGAVTSHTVAEQLACMGFEVERKRVEVPGLTLKCVGNYHVTIRLYEEICAVVPVTIKNQSEADSVSE
>SEQF2545_AGK83700.1 ribosomal protein S18 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAEDHPSVDLDTHLSSPRESEESAPKKNRQFYRKKVCRFCTQKLLADYKDPDTLRRFITERGKILPRRITGTCAKHQRRV
ALEVKRSRAVALLPFVLTE
>SEQF2545_AGK83701.1 single-strand DNA-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MADVNHVVLVGRLTRDAELKYTSAGGALCRFSVAINRRRKSGDDWVEEVNFFDIVLWGRQGEVISQYLIKGKQVAVEGEL
RQSRWEQEGQSRSKVEISATNVQLLGSVLGGAARAEDGEFSSSRVAAESTAGRVRGTSSDSRSPTGDILGEKRGLDATSS
LDEADFSSSDLDTVPF
>SEQF2545_AGK83702.1 ribosomal protein S6 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRTYELMAVFSAHEDLFLQGSTAVRALLQENDAVIAREDHIGERELAYPLKKQKRGRYLLFIVQCEPGKVRELDHKLRLR
HDLLTHLFVRVDS
>SEQF2545_AGK83703.1 hypothetical protein TPFB_0063a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLGDKYCLETQNSAPQTSPHIRDRRGHTGKRTFCEQVPHLVCRKEHTHECTPSDDAAPSAASDKRTKDLMRHTDLRYAGV
SPRVLRTLLLLVG
>SEQF2545_AGK83704.1 hypothetical protein TPFB_0064 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSFYPMLPTAQRRLRGYIRACAPYGRRGEEPVRRRCAFLCARVGHVCVGRSVVQNFVFQDNIYHLARSIDVLYEGLQLNL
DECLYAEKVVYDVRFFDHALQKLCAHIDRQSHFPDYLPILHCLFSCGARFLNLLNFLIHRASPVTAQVEFTRMLPFIEKR
HSALHENLARSIQEVDTSADASHVVSQDEIDELLEH
>SEQF2545_AGK83705.1 putative SAM dependent methyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRITGGMLKNHVLRCPDGPIRPAMDRMRESLFAILGDMRGCSFLDLFAGSGVCGLEAYSRGAYPVVFVERNVRSFSVLLQ
NVQVALCRLECRCMAVERYIARARTLFHFVYLDPPFPYRFHAELLQRLSRASLCREGSVVMVHRPREKKLADKIDSLVRT
DQRVYGRSVVDFYRRDKAGLA
>SEQF2545_AGK83706.1 hypothetical protein TPFB_0066 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCEGMQRVLEGDTPYFVKGIQRPVSTLSDRDRALLNRRGNAYLNEGKLQEAARVFITTGYHDGLTRIGDVYMRKADVLTA
LRFYYFARNEQKMRPIVSALSVLIRCLI
>SEQF2545_AGK83707.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSYIILTPGGGMGCECSFPPFETVETGKRSVDADRIMRLSRDGYAFLKVNDLERAESEFGKILQIEADNNYALVGLGDAA
RKRRAYQEASDYYTRCLQHYPRNSYALFGLADCYKNMRRYVKAVEVWQQYLEQDSHNIAVLTRMADAYRKIHDFQNSRNL
YSQVVALDEHNSYALIGLAHLHYDFKKYREALIYWKKLLECAEHSVDIRVLTSIGNCYRKMKLFSQGLPYFQEALKRDPG
NFYGFFGMADCYRGMNMQERSIQYWEKILEKDTQNRVILTRIADAYRHIGEYEKAHQTYKRALDIDYDAYATLGLAVLCK
LQGRYEEAVVSLDRLVQLDRKNYRVYVELADCYRKLGQKQKALETLRPFQQFGVKNRVVSELMSELEGAS
>SEQF2545_AGK83708.1 hypothetical protein TPFB_0067a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAFAKCERLVAQVWLRDACRFGAFCVVVGVLLFVGGGAGLCDEGVERIWSGAAPFRGFCQKKSRRCVRLLSAFVGCRCSD
GLPQGALTSMR
>SEQF2545_AGK83709.1 putative Fe-S-cluster redox enzyme [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEWCCALSGLLPEEIQKVCAFAERFRGVQVFRWIAAGCTDFHAMSDLSSETRARLARACVISDTRVYTTLRDVDGTLKLG
IELKDKRRVEAVLLVDQVSRKTACLSCQVGCPMACAFCQTGQLGFARNLSASEIVEQFLHLERCVGTLDNVVFMGMGEPM
LNLDAVCRAIEILSHPQGRDLSEKRITISTSGHCRGIYSLADRALQVRLAVSLTTANAPLRARLMPRAAHDSLAKLKSAI
RYFNEKSGKRVTLELALMRGVNTSERHAQEVIDFAHGLNVHVNLIPWNPVASIHFETPREVEVAHFEALLMRARIPVTRR
YQRGNGIGGACGQLGKTAGV
>SEQF2545_AGK83710.1 hypothetical protein TPFB_0069 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKVRGIPVLQRRTWALVLLVLSSTSACVRKNSLEDVRFPSNSPIGEARRFAVITKAYVLLRDKPGVTGIVIAYARRKDIF
PVLGIDLLSKDKESALWVNVERGWLPWDCVQLYSSKAKALAASKKLS
>SEQF2545_AGK83711.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLPFYFLSVATNAAIGFILTVLDSQEESAHDCPFLYDATFSLVLALLSGIAAVCKCVNPIGAQLPVLGDLIPTLAGGTGC
ALFLHRYCVALSKPSPIPRTLVQYAKPLGLFSLAASILHLLFAPTLFL
>SEQF2545_AGK83712.1 S14 family endopeptidase ClpB [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNTDRYTVKASEALNDAISLAEAENHGQVEEEHLLHALLSQKDGIISPLIEKIGAKPDFLYDELLQCLRRKPRVTGPAAQ
TRCAPTLSKACARAERLALKNQDEYVSCEHLLLAISETDSNTARLLHSQGITSKTISAALKDIRGSKRVTSQDPESTFQC
LEKYCRDLTTLAREEKIDPVIGRDEEIRRVMQVLSRRTKNNPVLIGEPGVGKTAIVEGLARRIVSGDVPESLKGKRLLSL
DLGALVAGAKFRGEFEERLKAVIEAVQKSDGGVILFIDELHTLVGAGASEGSMDASNLLKPALARGELRSIGATTLNEYR
KYIEKDAALERRFQQVYCVQPTVEDTIAILRGLQEKYEVHHGVRIKDEALVAATVLSDRYITNRFLPDKAIDLVDEAASR
LKMEIESQPVELDQVERKILQLNIEKASLLKESDPASKERLEKLEKELAGFLERRAAMQVQWQNEKGRIEESRRYKEELE
RLRIEETMFSREGDLNKAAELRYGKIPELEKKIMLLTAEVEKKSGLEGQLLREEVCEEDIAKIISMWTGIPVSKMMASEQ
QKYLQLESVLMQRVVGQDEAVRVISDAIRRNKAGLSDTRRPLGSFLCVGPTGVGKTELARTLADFLFNDERALTRIDMSE
YMEKHAISRLIGAPPGYVGYDEGGQLTEAVRRRPYSVLLFDEVEKAHQDVFNIFLQILDDGRLTDGQGRVVDFRNTIIIM
TSNIGSEHILSARESRTHTSDLPVPETQSTEEQTLPEQIRGLLHTYFRPEFLNRIDEVLIFKRLTRKHIRLITDIQLQMV
VERLESRHIKLRVRDAAKAYLAERGYDDTFGARPLKRAIQTELENALAREILSGRFRGGSTIVVDMCKDALCFTEQTS
>SEQF2545_AGK83713.1 glutaredoxin-related protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEKTLTLFGSNHCGQCATALEYLRSNHINFEYVDITGSGKNLKRFLKMRDSMPLFDDVKKEGRIGIPCLSVNDGEQVFLG
VEGLDLSAFR
>SEQF2545_AGK83714.1 HDOD domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHFARVVKSIHSVYSLPMCDTQIVVDTEKIRKAIELQLPIAITTYTLPRDMDIYIGQVAKTILDLIGQPHVKDYLTYCIS
ELTTNAKKANTKRIYFREKGLDIFDPQDYKRGMKSFKEESLENINHYLKLQQQEGLYVKVTMQVLSHALVIEVINNCKMT
PMEFKRVFDKRVRARRYSGLEEALAHILDNSEGAGLGLVIMMLMLKKLGLEEDVYRLVVEEDRTISRMVVPRNIEIQTQT
TKLAASIADRIDDIPQLPSKLLEIQRAIENPDVQLSDIVALISQDVALVTDLLKLVNSARFGMNKRCLDISEAVKRVGLR
GLQNLLYSVGAGRVLQSTDDERKQLWNQAYRTGYFALGLAKATGDQALIADSYICGLLHNLGEVVFTSAYPEMLIKLTEI
QAERNIPPHVLDTIMSDVGHAEIGAALAQRWNLPEPVINTIRFHHNLPHAPEEYKPLISTVAFANMTIRFLDGETPYEQI
PRSLLSFFRIQSEQQLRTTAQTLQSSFEAEQTA
>SEQF2545_AGK83715.1 hypothetical protein TPFB_0073a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSTYSLLPLQPNGADSRTLFSPLSTKTYTAPTRVCILAQGKLCISRVLSKAYTACTVCPCVIHK
>SEQF2545_AGK83716.1 sugar ABC superfamily ATP binding cassette transporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCFARSRLFSRGAVGTVCCTVLFLACRVRTPSSVPLRSGSVRAAVPEATSFHWRRYAGTRLRVCFPYHASYRALKAIVPE
FESLTGIAVEIDWLQYARMHDKQVLELSKPRGDYDLIAMLCTWKTEYASRGLLRSLDSFFQNPSLCMPHYDFEDLIPVYV
ETIGYVGGRKPWLGGPGAFLCAVPFGAETSILAYRKDIFHKYRIKVPENYDELLDACKRLRERAQLYGLASRGASGQQAL
HAYLLHAAPFGAKVLDDSLVPAFHRSRSIATLRWMQEMFAYGPPGMASFAQNEALQAFLQGQTGMYLDTNMIGPLVRDPT
RSAIRPHHVGFALHPMAQVRAGEVGGFGLAIPHNSAAPEAAFLLLQWITAPQTGRRVVEQGALPFRQSQLADRALRARFA
EFEVLERQLAHCDPDWRPIVPTWGELGTLLGIGINEVLTGVSEPEEAMSALVLPARRILRRHAHARYVP
>SEQF2545_AGK83717.1 sugar ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGKSMSKPRDTVSAYCFSAPALVLLMFVLVLPAFLGLRMSFFQWQLSALRTQPVFVGFENYRELFSSIHFWASVRTTLVF
TLSVVVLEVVLGLALALVLEHGVPGLRFFRTVFVLPMMIAPVVVGVLWGFLYHPQFGKINYALQAFELGPVLWLANPRLA
LLSVILTDVWQWTPFVFLVLLAGLQGIPQHLLYAAKVDGANYMQTLLHIKIPHIAPVLGIATVLRLIDSFRGLVVIMTLT
NGGPGVATEILPLHLQRIAFEDHRLGKASAVAVLLFLLTSLLTCIFILLTMRRQAR
>SEQF2545_AGK83718.1 sugar ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNMIFLKWRTALVLCLLSCIALVSMFPLYEMVATSLKRDADAFRLPPAWFFIPTIENYRQLLQEHHFGRALYNSLVVTLS
STVVSVSAGAAAAYAMQRFRYRGKKAITVALLLLRVIPPVVLVIPIFVWWTALGLVNSLAGLALVYGALNVPFNVWVITT
FVAEIPPSLDESAKLDGCSHWMIFTRIVMPLITPALAVVSIFTFRFAWNEYMLGFALTNRKTRTLPVALSLFLTDSGVEW
GRITAAATLIAIPACVFTFAAAKYLVVGLTAGAVKG
>SEQF2545_AGK83719.1 capsular polysaccharide biosynthesis protein CapD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCGASLGDCVGSCARVNALYVGRDGVGAENVWGCGRSAVRESAHRDGIYIVGAGFAGSVLAREIQTKKVLGTVIAFLDDD
PCKIGSNLHGVPVLGPIFEVARIVRITPHDHALIAIPSISIERLRDIYLTLRAAGFTVIKLLPALAQIIDGTAHLVQTRE
IDPQDLLTRTPVTINLKKSLAYLCGKRVLVTGAGGSIGSELACQLLSGDVERLYLFGHGENSIYQIDKKIRRLQEEGVGS
RTVIVPVIGDLKDAAYVRYLIEQLRCDAVFHAAAYKHVPMMELNPVSVIENNVFGTKFLLDACIACRVKRFVLLSTDKAV
DPVSIYGVSKMLNEKNVLYAAERVRDFGHDAAYMFVRFGNVLGSRGSIMPLFIEQIKKGGPVTVTDPAMTRFFMTIPEAC
SLVLQVGGVGVNGASYLLDMGEPVSIMETAQQLIRYFGYEPDRDIPIHVVGLRPGERLSEPLVSKDERIEPTVYPKVLRL
REREPLDFAHLERLWDQLYPYCFPSGEKVRYRHKEGLVRVLCDSCATLKQRYMPNSEA
>SEQF2545_AGK83720.1 DegT/DnrJ/EryC1/StrS family pyridoxal dependent aminotransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEGTVKKKKEGVRDDNAQHAVFNKQVPFFVPSFSEAEERAVCDVLRSGWITTGTQALAFEKEFAAYVGAPYACAVNSATS
GLLLTFDAMGIGPDSKILTSPYTFVSTASSALHLGAQVVYADIERDSYNISAECVEACLKKDARIRAIVPIHIAGNVCNM
RDLNALARKYQVAVVEDAAHAFPSKTACGYAGTLSHAGVFSFYATKPLTTGEGGMVCTNDAKLAARIACLRSHGIDRAIW
DRYTNGTAPWRYDVTSLGWKCNLPDILAAIGRVQLQKAAHLFAQRARIAAAFTRAFSRYEFFCTPPDGDGNAWHLYLLRL
VPGTLSVSRDEFVRLLQERGLGVSMHFIPHFEMTFFKKSLCVRAEDFPECAHKYQHTLTLPLWPGMDDSCVAYVIETVVR
TAQECAKGRAYI
>SEQF2545_AGK83721.1 bifunctional aldehyde oxidase/xanthine dehydrogenase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRGVCDRDRGAHRTRMCKGKSIYMSVFVSDGARTGSVYAQLVRAPRVAGLLLNIDIPSLPDGYSFYTAAHIPGCNAVRCG
ENTVPVFAHGEVVYAGEPVGILIGPDEHVVRNLVQDVVVHTCAERACASEILCGISEGEPLAQKVAVQGDAETAFKRASH
TVCSSCTFEPRVHYFAEMPEVQALPDAHGLHVYAATQWPAHMRKTIAQVLNISEHAVHVHPQQEALSCDGRIWFPSVMAS
QAALAAYCAKKPVRLSFSFQEYVQYCPKTPKITIAHRTALNAAHAVEGMFVFISLDAGAGNLLIDRMVAHMVHTALGNYA
IPRYRIECTAFRSNVGLTDVFNGWADAYTSNALEMHINQLCAELHIFPDEWRVAHMKDTRETQRFARLLAYLCEEGDFRR
KHAAFSMVNAVRKAHDTHAWRGIGLALGFQYDPSAMLARSGFSYVLQMTLHTDARIVVHSVPLSDSFKRVVVAFLIREFA
CLEDAIFFKSSDEAYGVDLLGPSVESVGMRVFARLVRKCVRAIQRQRFRKPLPITVQGSFNTAKKGQVYQVVTVAKSDVS
VPDAQSEQCASKVPVTADTSGKCEDMNGFTKMHGMSTHTPAACIIELELDALCVQPKIVRLWFVCDPGYVFCEKDVYRTV
SRSITRALSHVSVEKIWERARTPEYVIIDPSDTPPYHVTLLSSNAAARAVGTVAEGIVPAAYYAALRQILPISQNATHKV
PFVARDIFYEMFSLSADDSL
>SEQF2545_AGK83722.1 xanthine dehydrogenase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNIRFTLNTEQVHVDAMPHERLSTVLRRCFHLPSIKGSHGHGENGASTILFNGEAVSAYIIPFFLAHETQIVTLDFFQKT
KRGRWIVACFAQHHISFCGYCDAGKILTAESLLQRNSVPNEEEVRHAFSGMQCRCTDINALIRALQRMPACHEFS
>SEQF2545_AGK83723.1 xanthine dehydrogenase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHLYKNSESSVIYYVKSLGQLCAVLRNVAQVQPVGGGTGLVQYQITPVLTLPSHLVVLNGVPELKDISKTEHFLEFGGAV
SLQAIVQLGRKNIPVALHEALSHAANPGIRTLATIGGNIAGTRPHASALAPLIALDAKMEVRTGHENFWISVAHYAHARS
DTPRHRSHVITRIRLPTDYWDFSYYRRIGSRALFGERADFVFLAQQQKNALSEMRMVFFSDVVMRNREFDNLLLGRAIPL
SAGDIAAIVYRSREFFAPESFKSAYIAHCFFHLLEDCLRRLR
>SEQF2545_AGK83724.1 sigma-54 dependent transcriptional regulator [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNCSGCPARALSPLPAEKSLEMILDALYEIARYELAVVLSFESSQILRVRKARGPLYTPRLQHHTIDLTKRQDLARILSQ
KSPYLFDPTLAHTDTYTELIPMPQNHSCLIAPLYIDDTPIGMLTLDHRLCEQFTPDVVRFITTLSKLISLAVAQTDASET
LSQKSHALLTERNALLAPQSPAFKNMIGTSPAWTRTLDAIKLVAASDLPVLVCGETGTGKELVARTVHQLSTRSDKPFVP
VNCSALVHSLAESELFGHEKGAFSGAVGTHRGRFELAHGGTLFLDEVGDLPLELQPKLLRVLQDGVFERVGGERSVSVSV
RIIAATNINLSEAVTQGKFREDLLYRLDVFPLSLPPLRERAEDVALLAEHFIQKIKTRPGFERTQLSPSAFKKIFSLTFP
GNVRELRNLLERAALLARGDTIGAEHLVCRTPESGTQTTVYPREHTEVSESVQPAIPLCIRDSSCMVRCTQGKKEETTLV
VNFHQAQRAAIQAALDASNGKIYGANGAAEILGLKPSTLQSKMKKLGL
>SEQF2545_AGK83725.1 hypothetical protein TPFB_0082a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQDSPNSSWGPSIEEKGISVQFSAWSLWACRVQGMVFVFRILFLAFFMGYNRAHETRVDKCSDVSLRMGKCAGRISRRRC
KGIVPYYSLRSRRTALWRFG
>SEQF2545_AGK83726.1 hypothetical protein TPFB_0083 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFPCVWANAQGEFLAGGAKGLYRITPYAQDVLLSGVSVSKIIAAGENWFLLTSRGVMTSRDLRTFAHVGEQLPKKVVKKI
VDREKVFVSQPQPLKDLEVHPDNGAVLVTATNDAVFLSKNGGRTWQNLGCNANSSGIKAVAVLDFPDETGKPVLTVFVSH
SLRGIAWMQPEKGRFWTDISATLALGPEATEEISDIAVRRSVHGNELFASYTFVPKIVRLNWAKKRFQDVRVWTAALKDA
RCIDGLSASVASLVGCRDGSLFEIPLIMPRPFDLARLEQDLRRIPDQILCAWVPRHVSQTGDALSLSELWLLHDRSSLAK
EGRFARADLKKGIYVPAHHIKDPKLRAMHFKTIADNKLNMLVYDMKDELGMVRYQSQDPFVRSVGAVRPFVDMKTFVKQA
KEKKLYLIARIVVFKDKYLFRWNGFELAVKAGGKPWQGYKNGALRKEEIHEHWVDPYNEKVWRYNVAIAKEAIEFGFDEV
QFDYIRFPTDGDNLHQAEYPARESGMDRESALMSFLAYARERIDAPISIDIYGANGWYRTGARTGQDVELLAEYVDVICP
MFYPSHFSQSFLAYAPAQERPYRIYYYGAYRNRVLARNRVVIRPWVQAFYLPVSYDRAYYGEDYVQRQVAGIRESIDEGY
TYWNNSGRYSDVRPDDARLR
>SEQF2545_AGK83727.1 hypothetical protein TPFB_0084 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVVNAVVGADEASARLREYCSGLPDVEKKIAESTSPEGAKLVSDFGIGSVPMVVILDEDSSELFRTADIGELEKFFS
>SEQF2545_AGK83728.1 PTS family fructose (fru) porter component IIA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNLETVLTPETVSLHLKGSTKEEIIDEMLEMFVRAGRVSDKVAARECVLDRERKMSTGMKHGIAIPHGKTNSVSSLVAGV
GVSDSPVDFDSLDQEPCRIFIMTLSPLDVTGPHLQFLAEISLLFKSSEKRREILDATSKAEVIKILTE
>SEQF2545_AGK83729.1 PilZ domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTFCLLGLYHARMGFATREQLNRYYDLYKDVDVTFSKDVMQALCFNARQVCVRSAGGQCSCVMNSVSMVGAKVILSRKSS
LLESIQVEGASVSIRFSFFESDARDAVSFFVTARVLGVEDYAESTELVVLSVAYTQRIPDMLIERLGLLVEANISSKKRK
SERIAVNKESMRRIGLMRAETIVFIQAIPRRCVLRDVSFGGAKFIMMGVAPFLKGKETVLKLDFEEPSTSMSIRGHVVRA
DQVEGRKDLVAVAMEYDFDVVPVAYRMCLNRYASDRCRRFPGTDEDCSAASAGDPGRSSAGAEGIDLSVPFSLS
>SEQF2545_AGK83730.1 hypothetical protein TPFB_0087 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLKRIESVLYKAFEEHVSFYLHRTPAALSLLLLGLLSCVACRTNSLETAQIAFCTGGQYVPVVVELALTEEAQRRGYMGR
TRIPDGTGMLFVYKQDTRLSFWMKDTPHPLSLAFLDAQGAIVQIEDLVPLSTHSVRSNRSVRYALEVPRGWFVRSKLLVG
ARLSARSLARIRRHADPPKGQSGDKRH
>SEQF2545_AGK83731.1 hypothetical protein TPFB_0088 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNYAKNCMALALGGVLHMQSYLCSSPSPSRGAGGARMLATVTPLSQTHSLEKIPAVYRALSLGMGVTEVKEALKKDSIFG
YRGERDVSLLMSENRILIETTGPHFIARSWFQFYRDRLYAMTFKLNTDAIDYYSVYENLCKKYGEPHKLSPRVALWEDAS
TRLVLERPLIIKYIDIRAFNEQLSARDTQKSNAEKDRKRFVQGF
>SEQF2545_AGK83732.1 cAMP-dependent protein kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLQLTFVNFKKGSYILVEGKADADLFYIIHSGQVCIAKQVEIVAEEEGNVLTAGNFLGVVACMSRHNQIETAVALTDVVL
IAIRYEQFPQLIEKNAAIAMKIILSFTKKMRYLNEALTQLTLKKHTDVDVSHLFAIGEYYVKMTKFELALYAYYHYLKES
PKGTYAEEARKRFVAIKSTGVKVPVEILEPNILEATRCYDREAMVFCECQLGNEFYIIQKGHVKITKIVDNNEVVLAILK
EGDMFGEMALLENKPRSASAIVMSDGCQLLAVNRKNFQQLVATQPQLTARLTTTLADRIWSMYRQLANTLLPEPTEKMYD
MLAIQLEKIRYIPSTGKAYDFEFGPIELAHMCGFPKDIVSQVTEDFLREPIVRCVDNKISVTDDLELVKRVAYFKKKRTL
AKARKDPHNRQ
>SEQF2545_AGK83733.1 UDP-N-acetylmuramate dehydrogenase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFAHRIRARRITRRNVPLAERCSFRIGGAAQFWAEPRSCTQLRALIEEAQRARIPLSLIGGGSNVLIADEGVPGLMLSLR
RFRSLHTQTQRDGSVLVHAGAGLPVAALLAFCAHHALRGLETFAGLPGSVGGAAYMNARCYGRAIADCFHSARTLVLHPV
RSRAKELPEVRKNAQDKRGECLGLDGGPFTCSSFQTVFARAGDWGYKRSPFQSPHGVELHAGRRLILSLCVRLTPGNPAQ
IRKHMQEKIADRISKGQFRFPSAGSAFKNNPAFGKPSGILIEEAGLRGTSCGAAQVAPWHGNLIINTGNATAHQVRTLLR
VVRQRVFETHGVWLEREIIFSGESVRMTSSSRDS
>SEQF2545_AGK83734.1 cysteine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MALRVYNTLTRQQEHFQPWEHGHVRLYGCGPTVYNYPHLGNLRAYVFQDTVRRTLHFLGYRVTYVMNITDVGHLESDADS
GEDKLVRSAQAHGHSVLQVAAHYRAAFFRDTALLGIEEPSIVCNASDCIQDMIAFIEQLLARGHAYCAGGNVYFDVRSFP
SYESFGSAAVEDVQEGEDAARARVAHDTHKRDARDFVLWFTRSKFVRHALTWDSPWGRGYPGWHIGCSAMSMKFLGPRCD
IHIGGVDHIRVHHRNERAQCEAITGAPWVRYWLHHEFLLMQLQKRAVHADMGSSVVSSFSKMSKSCGQFLTLSSLQERGF
QPADFRFFLLSGQYRTQLAFSWDALKTARAARRSFVRRVARVVDAARATTGSVRGTSAECAAERVCESRASESELLLTDF
RAALEDDFSTPRALSALQKLVRDTSVPPSLCVSALQVADTVLGLGIIQEATASLSAQVPAGDTLPQRPLPSEEWIGQLVR
ARAHARQTRDFPRADEIRRQLKAEGIELEDTHLGTIWKRV
>SEQF2545_AGK83735.1 DNA-directed RNA polymerase sigma subunit RpoE [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLHEQELLRAQDDADFKLMYEQLVPVLYRVAYNVVREEDIAEGLCHDAFIAMTEKRMEFPSLSDAKYWLIRVVKNASLNY
AKRRVRERHSCEQASREHVCEPDTGELRLLRIETIEQVRAALDRLPEHLRVVLQLREYGDLNYKEIGRILGISEGNVKVR
VFRARERLAKYLGETDAYLS
>SEQF2545_AGK83736.1 putative transcriptional regulator (anti-sigma factor) [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRTCPDCAAWCAYVDGEGSQLQRREMCAHLQGCTHCATCVAHYRAMRSLVKHADRVSSRDFTMAFPYLRVRHRVASCMPR
PWWQARSSPLSAAGPVRAAALAVAVASLCVCTLLLTHIVERRPVSRAGEASFTPIVPMRVRAPVGYARGVKVFGPAVSAN
SNVLRKPAAVFTVCAFAQLYGSDPAYEMETVPVRLSVIPVPSYVLNASKAQFFSP
>SEQF2545_AGK83737.1 phosphate acetyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTFVESMQRRAVLAQKRLVLPEACEQRTLEAARLIVFRNIAAKVFLVGCERDIKNTADRCGIDLTDMVVIDPSVSKHRDQ
FAERYFQKRKHKGISLAQAAEDMRDPLRFAAMMLDQGHADAMVAGAENTTARVLRAGLTIIGTLPSVKTASSCFVMDTNN
PRLGGTRGLFIFSDCAVIPTPTAEQLADIACSAAESCRTFIGEEPTVALLSYSTKGSGGDSDENILRVREAVRILHERRV
DFTFDGELQLDAALVPKITEKKAPHSPITGKVNTLVFPDLSSGNIGYKLVQRLSDADAYGPFLQGFAKPLSDLSRGCSVE
DIVAACAVTLVQSNGR
>SEQF2545_AGK83738.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTSTQARIREAVRAGSVRDYARAIRILEELAASGKAEGCHHPDGGAVYERGAQEEWNEGSSESHAHGGDGTQDAYPEIYL
YLARAYHAQRQYARAVAYATVYSRRVPRDGAGWFFLGRSYLALHQGGYAVAALRRSVRENPASLGAQALLGLAYLRSKKP
RAARMVFEQALAQYPDNKRLNAGYLNSLFVEAVQHLKRGSADLARQMFTFLINQDVDGVAPRLYLAHAFRSLKHFPEALT
QYRAASAFAPHDPALKWYEAAMLVEMGCLSQAAALLSTLGVSIERDQISDRFLVMGAVRKHMEEGAWARAASAAHLYLKT
FGGSVEIHLLMAEVHRRAGRVNVALNHYTRAMKIEPKNCYPHYGLMVCLQEARRWQELAKAIRRAEGAGCDAQDCYYYRV
ITAAHLSNPPEEVLPHLQELARGGKADQLLFNALGVTYVRLGMADLALRWYEKTLLLDAEDEEACVGLIACYEALCDDAR
AYTQYGAYLSRWRDNRVIRKDFIAFLERTERWSEAADHIELLASGERGGFWGTRLAFARKKAGQYRQAAIIYRALLRQRP
DERVLLHNLVYCLDKMGQADAGLRLLRAACNAFGTSVESRLIEGVLCLHTRRINAAIRTLRAVLEQQPGYTAASELLAKA
YALASSRA
>SEQF2545_AGK83739.1 putative DnaK suppressor protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDQSFVEEMKVSLVERKRSLARSLTTNNEDFQAIVAGVDPKDSADIASDDMDRKMLESLSAKDLRCLQQIESALLRIEQG
RYGKCADCGESIPEDRLRAIPYSLMCIECQSARESKRRAF
>SEQF2545_AGK83740.1 initiation factor IF1 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTKEEAIEVDGVVKEALPNTTFRVQLQNGHEILAYLSGRMRKHYIRIVPGDSVKVALSPYDLSRGRIMFRER
>SEQF2545_AGK83741.1 chaperone DnaJ [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSERTVPDHYAILGVAADASEEHIKKAFRAQALKYHPDKNPGGACAEDQFKRINAAYAVLSDRASRARYDAERAGGAFWS
SRAGRDASEGFGAWTSGTDDKAGARTRYTHTHGPWRGHARETEHFEGWYTFFGGFPGNGWSYWSSADAPPDPAGPTARTG
SRKDGARLLIQGAALVLLALFGLRFFLVFGFFGIAFSVSCLARGVHTLRAGLSILLEG
>SEQF2545_AGK83742.1 UMP kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVTVLSLGGSIVAPETPDIELLGRFVRSVQRYLYEDASRKLIVVSGGGAPARTYQNAYRALRRSLSSPACAKPAHEGDNQ
EDRELYATAEHVELDWIGIMATRLNAQLLKSLFGILCPNPVVYDPTAANVFSGQVLVAAGWKPGFSTDTDAVLLAERYSA
KTVINLSDVAHVYTGDPRSDKDAKALTSLSWDDFLLLVDKEWVPGSHVPFDPVASVRAKKSGIQVICATGRDLPNLERIL
NRQEFVGTTIG
>SEQF2545_AGK83743.1 TlpA family thioredoxin-disulfide reductase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSCSRTTGALRAVPLVFRSVLVLAVWGVSCVQAADVAHNADVPSRSLKALERFRFFVYPKPLDLSSDFHAKALKGEALVP
SLFKGKVTLLNFWATWCPPCRAEMPSMDRMQALMRGNDFQIVAVNVGDSRKQVESFIARGKHTFPIYLDEEGSLGSVFAS
RGLPTTYVVDKAGRIVAVVVGSVEYDQPELVALFKELARD
>SEQF2545_AGK83744.1 DsbD family disulfide bond dehydrogenase D [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTSVPGVVGSFLAGLLSFLSPCVLPLIPAYVSFISGESLGSIRAGAARLQVFLSSVFFVLGLTTVFVLFSIVFSGGVQLA
GAGVLTVLTRVAGVGVILLGLNTIFDVVPFLRVERRMHTTVRRVGVFRAYLFGLLFATGWTPCVGPILSSLLFYAASSGQ
LLHAAGLLTVYALGLGLPFVFAGIFFGRAERVFAWVKRHMHAVKLASGMLIVFFGLLMLTSGLQALSRLFLRAGFALEEY
STRGITPLRQIAALLAQWFLYQGV
>SEQF2545_AGK83745.1 UvrD/REP family ATP-dependent DNA helicase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLSTLNPEQRRAVTTLEGPLLIIAGAGSGKTRVITARIAYMLECGILQSRILALTFTNKAAHEMSERIKALTGKPLRNMT
VSTFHAFGVTILREHIHVLGWRKNFSIYDENDKRALIREAAKEVHLLPEVLDTNCVSTLFSAIKMQRKNLKELQHKERAL
WHEYQTALKLFNAVDFDDLIVLPIQIFSEYPDILASYKSRYHYILVDEFQDTSAQQYRLMKMLATQNICVVGDDDQSIYS
WRGAHHDNILSFEKDFPYATEITLEQNYRSTGTILAAANGVIAHNTQRKEKALWSGNDSGKPIEIFNPETERDEAIFIAN
TILAEQIRASYSFSSFGVLLRTNSFMRIIEDVFLQENIPYRVSGGMSFFQRKEIKDVLSYLRVISNPDDDVNLLRIINTP
RRGIGKKTLHLVSDIANTQQCSVFNALNQIINKTHAVDLKESHRTAVENFLQLITQARTHLLSGKNLAYKVRKFVEDIQY
FNYLIQEFQKNEHAARFKFLQIEHLVESIEHWEQSSEHGSLYDYLNRVTLLARDNVQKETEGAVSLMTIHASKGLEFPVV
FIAGVEAGTIPHERSIEEVHSIEEERRLFYVAITRAKEKLYLTHCRTRKRGGKREERTASPFLDEIPKHLVRAHAPEGKI
SEEEVTRAFTRIKKLFT
>SEQF2545_AGK83746.1 ATP-dependent helicase RecQ [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGNTSDWVEMDGLRYVYAAQGAAPMPAPTDNPACDAHMSHDVIARTAQAVFGIRALFPWQRLVIANILDAAHACTHTTPF
AAAGSSQTDATRVTHVDDAQPEDNFVGAMQDTRFDQDGVSRAHQVVLLPTGAGKSLCFQVPALFLEGPTLVVYPLLSLMR
DQCRRMQAVGFSVILLRGGLNAQERAYMYAQLDRCAEAYGRMRGVTPPAHQTAEFSLADSISFDASLFSDDVSTFSKVVH
VDERLAQKRTESRRGVCIIASPEILTQPALRARVRACRVAHLVIDEAHCVSEWGDSFRPDYVRLGELVQDLAPQVVTAFT
ATASQTVLARIMEVLFGGRAHVLQGTVDRPNIRYTVRTVLCKQTALTQLVARCVRPAVIFCARRVQVERVAHHLRTCLSD
TQIRFYHAGLQREEKETVERWFHTHDSAVLVTTCAWGMGVDKPNVRTVIHVDAPLTVEAYVQEVGRAGRDGMRADAFLLW
SPRDARSIETLPHAQRVRAHVLRHFAESGRCRRAVLLESLGEQNVCAGCDVCAGTARFVCEDVEALLQFLKKNARRFTVS
SLVQHLALHQKVLSVADVHALLYYALETGRVKKNIHSCGVMSCMLHVNDSASKSYLQESKKDGENIQLPCIFRELRAFLW
PSG
>SEQF2545_AGK83747.1 bifunctional 5'-nucleotidase/UDP-sugar diphosphatase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRFIPHRVIHAVCIGLALVGCRKLDSRAGDFELTIIHINDHHSHLEPEPLELAVAGERLRAAVGGYAALVHEIQRLRAE
SKNALVLHAGDALIGTLYSTLFRGRADAVLMNHAGFDFFTLGNHEFDNGNEGLKEFLHYLEVPVLSANVVPNAASTLHGL
WKPSAIVERAGERIGVIGLDTVKKTVESSSPGKDINFIDEIEAVRRATVEMQQQGVNKIILLSHAGFEKNCEIAQNISGI
DVIVSGDTHYLLGDESLGRLGLPVVGEYPRKIMSPAGEPVYVVEAWEYGKCLGELNVVFDRTGVITSAVGMPRFLLHTNT
LQKKGADRKNYPLEEAEREALLVALRMTPEIIFAQENDQIISVLEEFKKEKEALGAQAIGVITGASMRGGSVHRVPDAQN
PQGSVATRFVAETMLSDIQSFGAGKVDCVIQNAGGARSNIQPGEITYNDAYTLLPFSNTLVLVDVSGAELKQIIEDALQF
ALGDGSTGAFPYGAGVRYEARQEPDEHGKRVIKLEVQKKDGAWVPVDERAPYRLGVNSYIARGKDGYKTLGEIVSTRGAE
DTYLRDAESLIKFLRAHKNFRAYTDSNVIFRLK
>SEQF2545_AGK83748.1 DNA-directed DNA polymerase I [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQEKKTLYLLDAYGLIYRSYHAFARAPLINDSGANVSAVYGFFRSLHTLLCHYRPRYFVAVFDSLTPTFRHVQYPAYKAK
RDKTSAELYAQIPLIEEILCALGITVLRHDGFEADDLIATLAKRVAAEHCHVVIISSDKDVLQLVCDTVQVLRLDIDHKW
TCCDAAYVQQRWTVMPTQLLDLFSLMGDSSDNVPGVRGIGPKTAAHLLHCFGTLDGIYRHTYSLKEALRTKIVCGKKDAF
FSRSLIELRDDVPCVFSLEDSCCIPLDVTSAARIFVREGLHALAQQYRACVQEIDTEATNDTLQMTESSVLTSGRCANEC
FLSQVEGRASTPEVNSVLKSELKTSAVSGAIPIENRDLRQDVMLARSAGHYRGVTDPVELKRIIDCACANGVVAFDCETD
GLHPHDTRLVGFSICFQEAEAFYVPLIVPDVSLHTESTQCTCARNTNVETEKECTEQHGVSASAVQDPAYVQAVMHQLRR
LWNDETLTLVMHNGKFDYHVMHRAGVFEHCACNIFDTMVAAWLLDPDRGTYGMDVLAASFFQIRTITFEEVVAKGQTFAH
VPYECAVRYAAEDADITFRLYHYLKLRLETAGLLSVFETIEMPLLPILARMEEVGIFLRKDVVQQLTRSFSDLIQQYEHD
IFSLAGHEFNIGSPKQLQTVLFQELHLPPGKKNTQGYSTDHSVLKKLARKHPIAEKILLFRDLSKLRSTYTESLAKLADQ
TGRVHTSFVQIGTATGRLSSRNPNLQNIPIKSTEGRKIRQAFQATVGHELISADYTQIELVVLAHLSQDRNLLNAFRQHI
DIHALTAAYIFNVSIDDVQPAMRRIAKTINFGIVYGMSAFRLSDELKISQKEAQSFIYRYFETYPGVYAFSTQVAEQTRK
TGYVTSLAGRRRYIRTIDSRNTLERARAERMALNTQIQSSAADIVKIAMIAIQRAFARRPLRAQLLLQVHDELIFEAPAA
ETAIVKEILFAEMEHAVELSIPLRIHVESGNSWGDFH
>SEQF2545_AGK83749.1 BCCT family betaine/carnitine/choline transporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQKEKCDFSVSLIPLGIVISCALLFISFPDISHRVIGTLLNILVNKLGFFYILTGLFFLGTTLTIAFSRYGAVYLGTTRT
ARYSNFTWGSMIFTSTMAADILYWSLIEWAHYFTQAPFIAEHSPPTERQEWAAAYPLFHWGIIPWSFYVLLAVAFGYMLH
VKKRHTHKISEACRPLLGAYVDGIIGEAIDICSVVGLLLGVATTFSLATPLLSLMVSLLFGISNTQLLALALLCVIALVY
TTAVLLGTQGISKLSRAAVYCFSTVLVFFLCAGPTVYLIETGITAIGKMLQNFFLMATWMDPSRISLQETDGTLGFPQRW
TIFYWAYWITWSVATPFFIGAISEGRTIRNTIVGGLCWGIAGTYGSFIVLGNYGLYLQTHHLLPAAYLLRAGNTPAEVII
AIIQTLPCAYIVMALLAATMIAFYASTFDALTLIIASYSQKSVAPGEEPRQIMKSFWAVACILLPASLIFSQSTLMHLKS
LAIIAAFPLALIMLCVVASFFKELRAEVTS
>SEQF2545_AGK83750.1 putative bifunctional choline-phosphate cytidylyltransferase/choline kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MESAGLLETHGTFGARTRSLTPLAHSQYQSCRVHNAVIMAAGFGSRCVPLTYATPKGLLKVFGEPMIERQIRQLHEVGIT
DITVVVGYLKEAFEYLVDKHDVTLIYNPDYETANNLSTLYHARHLLRNTYILSSDNWLRENIYHSHEWDSWYTAVKTQGK
TKEWVLKTGLYDKITAVKIGGRSGWIMYGPAYFSASFSKKIIPLIEAAYMRPENRAWFWEDVFMRNTKSLTMFANKQADN
LIYEFESLDELRKFDFAYMVSSDNEWMRVISHVFNQPEMTIGKLRPLKAGMTNKSFIFELNDKPYLFRIPGEGTELLVNR
FQEAAVYEAIKPLNICDTLVHLEPARGIKITVFHKDCRSANPSDPADLDLCMRIARKLHQSGICVAHRFDFRSRIAYYEK
LALDQYSILYADYRSVREKMNTLLAIVDSVDKPCVLTHVDLTPDNFLLCDGSAQLIDWEYAGMCDPLVDIAMFSLYAHFN
TAQIEDLMYRYFQRNPHGEERLRVFCYIALGGFLWSLWTSYKQALGISFGDYGLKMYRYAKEYYEAVQTLLKTHRADHAE
RKM
>SEQF2545_AGK83751.1 6-phosphofructokinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAHLPKEYDFSIESLGESKIPSPIYLSHTLGDFIPNYVSDNEYISHELSARLGETVGPFTHKNLMERAGPRQKIFFNPHH
VHAGIVTCGGLCPGLNDVIRAIVRCLWGRYGVKRISGIRFGYKGLLPDYNFDILPLTPEVIDNCHKTGGSLLGTSRGGGN
RVVDIVDGIERLNLHILFIIGGDGSQKGAKEIADEIKHRNLKISIIGIPKTVDNDISFVQKSFGFDTAIVKATEAVAAAH
MEARSQINGIGLVKLMGRESGFIATYTAIASHETNFVLIPEVSFDLDGPNGLLAHLEKRIALRKHAVLVVAEGAGQDLMV
NADGVPSGDSQGGSLRVSSGTDASGNKRLADIGLFLKEKIGVYFKEKRIHINLKYIDPSYLIRSAVAAPIDSIYCERLGN
NAVHAAMCGKTKMIIGLVHNKFVHLPIDVVVCQRKHVNPEGSLWRDALDATGQPIVMKNII
>SEQF2545_AGK83752.1 putative rRNA (adenosine-2'-O-)-methyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVISGLRAIEEFLRAQPAALEGLHAGGKNSKTQQSCVRVLTLYYAAENARIKRLLGMAAARGIRITHTTCAVLDKLARSL
PPALRDHRGILAVLSSPSATPQGSHTRKKRPAVDSSQERTLLHALATHTHALVLVLDAITDPHNVGAIVRSADQFSVDAV
LLPHHHGAGGTETITRVSAGAVAWVPLVRVRNLVRTAGILKRSGFWLYGADVAGEAIGARTFPPKTALVLGNEGHGVSPL
LRTHCDALISIPTQGNVDSLNVSVAAGILLYEIRRSQQSPYSVQRQNEMNAQ
>SEQF2545_AGK83753.1 hypothetical protein TPFB_0110 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRGYGDAMNEQLSTFDKLVETLSTEDAQRMLADIGKALRTSEANAETPAKVKKKRAFARWDTREDSLAGETFFFRFWIGV
KSFFRSSSVEALYEETLLQRLGNDLKAHYAQYIDVKEKTFTKVFYDKMGELRKTQVFFDSLLACYNSDKGDFYLLLSSFI
TPVVYEQLMACSDPFAAQGDGTPSGLRASLLKRMDVALATLSGPHKTELYQAARAIEWMKVFCEVPVDRILLRFTVISPA
SAVCPITILQAELEKLACVIHDSKHIPDAVLQGLFVLKSKTSLHDAQVDNAAHAAAFLKEASAALVVIKDLSHSIPIEDF
VRFAGRNIRWQPRAIAGGEDWFVLFKNAWKKRFNEKWALWSTAQKRLVLKEQMLSLLGREQFSELTHRPWEGFWYQLVFR
REMSFVFLKNLFEDAYARVVSPPLNVILAEGSFYRRDELIEYTDAVNVLEQMGAKIRNFEVRLSPVGEWGVAFGAQRKEH
TVTMKSKGILEALIKVIDSEATVLLDATLKAFHCIGAMLASMIGASKTSAYATLTNWSDIRGSDNASFREQASQARAYVQ
TASRALVEMENLETTHL
>SEQF2545_AGK83754.1 DNA-directed RNA polymerase sigma subunit RpoN [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSVSLLFCIPFVGLVCRARGDMQQLVQQQRLVLNQRLVHGLCLLQLSRGDLKTEVLRAVQRNPLLEIRPSSARRTGKACY
LSLGDRRERMRARDRFQQLLENQPDKQVDNIRAVLREQVFYQKHEAIVLDLACAFIQMLDDHGFFSISPAIFQNMCGSMP
TALQEKIPQAIALIQRLEPQGCAVFNFKESLAVQARLRFERFSDPLYRCVINLLTHHSELLFCSDNMCDGRVSVHALTTQ
INSMGLCVQKVSSNDVKDILLLIKELHPFPGKCVSNAQRADTNMLLEPDVLITKTAHGFVTQINCTGIPTVVFRNDYCMH
SKAAEKNHALKACMHDALSLVSMLSYRERTLLDIAKTIVHYQCGFFDHGPAKLTPLRMTDVAHRTGLSVSTVSRIVRDKW
LQYGSQHFSLRYFFSPRVLSTEEYRDRSSLGQNYPSSPHSKVSVKHRISRLIQEVRTQRISLSDRRIAQLLGEQGIKCAR
RTVNKYRSELRTCSSS
>SEQF2545_AGK83755.1 bleomycin hydrolase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYLTKELLDTFAHEVAADPIHKAVAGAVARVGLEEAALNTEVARQHTHIFSTETKRGEMTNQKMSGRCWIFAALNAARVN
TMKKLDIETVEFSQNYLFFWDKLEKANFFLENILETLDEPLTSRLMAHLLANPVQDGGQWDMFSGLLEKYGLVPKECMPE
TFHSSNSRVLLAVLTRRLRKHAQLLRSAHEEGVALHTLREKKEAFLSSIYSILVKALGRPPEKFDFVYKDKEKKFHKVRD
LTPQKFFCDFVGWDLKNKVSLIHAPTADKPFGRAYTVKFLGTVKEAPCICYVNTPIEVLKEATASAIRAGEPVWFGCDVG
QMMTRKDGIMDTEIFGYESMLGTTPEFNKAERLDYGESLLTHAMVITGFDEDAQGNPVRWQVENSWGDDTGKKGMFSMSD
RWFDEYLYQITIDKKFVPQVWLDALEKPIIALEPWDPMGALADTPLYLKN
>SEQF2545_AGK83756.1 HflK protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRIPKWTPATWSVVAGCIGGVLGIVIVGIASPIRIISPTDNGVVTRFGKYHRTLEPGLHYLIPFVERVYKVPVTKVQKEE
FGFRTSKSSEQSHYVNNISHESLMLTGDLNIVDVEWVVQYRIVDPRAWVFNVESQERRQTIRDISKAVVNSLIGDRAILD
IMGPERSAIQMRAKDMMNVLLKRIGLGVLVSSVQLQNVVPPQEVQQAFEDVNIAIQDMNRLINEGKESYNREIPKARGDA
DKLIQEAMGYANERVNRAKGDVARFDSIYAEYVKAPHVTKTRLYLEGLGAILEKTENVLLIDKKLENLLTLKDISKVSKK
VVAGTREE
>SEQF2545_AGK83757.1 putative HflC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRKRGLQVHARVRPVLNIGIVVGVLLGGVVLLQPFYLIQEGQVALITQFGEIIKTNNTAGLYVRAPFLHHVHKYTAKLLR
VDGDPQKIPTKEKQFIEVDTTSRWRIEDVKKFYQSLGTYEAAYSRISDIIDSSVRDIITVNGLDDVVRSTNAINESNHSE
QFDVPVSQLAFDRGAEKTAHMTIEKGRESLAREISQAANDQLKDFGIVVVDVIFKGIKYSDELQASVFNRMVKERNQIAQ
MFRSTGEGKKAEWLGKLDNEKRSLLSKAYEEAERIKGEADARAAAVYAQSYGKSPEFYGFWKSLEVYKKSLPDTEKILST
DLEYFKHLYQH
>SEQF2545_AGK83758.1 phosphomethypyrimidine kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVKLLSIGGSDASGGAGIEADLKTFQEYGAFGVATLTAIVTMDPSRNWSHRVHSLEEDCVRDQLETAFAGVGVSAVKSGM
LASVHAIECVAEYLERFAVAAYVFDPVMVCKGSGDALHRELNELMIQKLLPRATVVTPNLFETAQIAGISVPRTVDEMKE
GARLIHERGASHVFVKGGGRLPGCKHALDVFYDGKTFHLVEDELVQSGWNHGAGCTVSAAITAGLGRGLTAYDAILSAKR
FVTTGLRHGFQVNQWVGTGNLSKWRDRFH
>SEQF2545_AGK83759.1 excision endonuclease subunit UvrB [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKEFKLHASFQPAGDQIAAIDALVRGLHAGARFQTLKGVTGSGKTFTVANVIARVQKPTLVISHNKTLSAQLYREFKGFF
PDNAVEYFVSYYDYYQPESYVPARDLYIEKDASINAEINRMRLSATFSLMERRDVIVVATVSCIYGLGLPESWRDLRIHV
EVNQCLDLEDLKRQLVSLQYERNDAVLECGRFRVRGDVIEIFPAYLEEFYRIECDWDRVVRIRRIHPVSGAVLREFEELT
VYPAKHFVLKEDAIPRAMDRIRQELHERLVQLTQENKLAEAARLKTRTEYDLEMLGEMGYCHGIENYSAPIAGRKSGEPP
VTLLHYFPKDFVLFVDESHVTLPQLGAMYEGDRVRKQNLIDFGFRLPCARDNRPLKDSEFEALLNQAVFISATPGVKERT
QSVQIVEQLIRPTGLLDPCIEVRKTDGQIEDICQRVKACSARNERSLVLTLTKKMAEDLTDYFNGLGIRTKYVHSEIETI
ERVEILTSLRAGEFEVLVGINLLREGIDLPEVAFIAILDANIVGFLRSTTSLIQIIGRAARNARGTVVMYADAISDAMRE
AIEETARRRKIQMAYNRAHGITPRTIKKSIEDILVREQEVKKDAARVQVAPLLRAADADVRTHAARKKMVQALRLHMKVC
ARELRFEEAALIRDKILQLQRQDEQNGV
>SEQF2545_AGK83760.1 Tpr protein C [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGKQVMQAGVLAGMVCAASGYAGVLTPQVSGTAQLQWGIAFQKNPHTVPGKHTHGFRTTNSLTISLPLVSKHTHTRRGEA
RSGVWAQLQLKDLAVELASSKSSTALSFTKPTASFQATLHCYGAYLTVGTSPSCVVNFAQLWKPFVTRAYSEKDTRYAPG
FSGSGAKLGYQAHNVGNSGVDVDIGFLSFLSNGAWDSTDATHSKYGFGADATLSYGVDRQRLLTLELAGNATLEQHYRKG
TEDSTNENKTALLWGVGGRLTLEPGAGFRFSFALDAGNQHQSDTDAQTQKERVSLAGEVFGRVVEKLVQNLLNIMMPLGI
TEQTTLIEMVGLAALIAEGTLGSAIQTVPAAGVPAALVSQLVPHIEQGVRDVFRSSDPRVVTAKLLAFLERAPMNALNID
ALLRMQWKWLSSGIYFATAGTNIFGKRVFATTRAHYFDFAGFLKLETKSGDPYTHLLTGLNAGVEARVYIPLTYVFYKNN
GGHLLDGVVPLGTINMPILGKAWCSYRIPLGSHAWLAPHTSVLGTTNRFNIINAAGNLVNERALQYQVGLTFSPFEKVEL
SAQWEQGVLSDVPYMGIAESIWSERHFGTFVCGMKVTW
>SEQF2545_AGK83761.1 hypothetical protein TPFB_0118 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFADKSLSALNAACQRAQQDLQSHCCSLGEHIVRGGAACDISGLGVQDTDISRCHALQRQRDQVAESILDIKSILQRQEE
LAALGKRVSKVLHRHARQERDVLRSFVAQYYATYAHVGLPALEPIYARTAELESTLQDLRAKRDQLLETCTFGSILERVG
LQAKSAVVQRRIRVLEAKIQKIITLCTPDVIAHPDVERMYHAGELSSALSAAYARLISDRGVYASNLQHSQELMDEQEAL
DARLRALDCGAKPLKRVAAFTAQVSELDEDINALCARIGAAYASCFFTEEGFAQPPLSQKTRPTVPDELSTLLRTVAEAR
MRVARAGYQVECAKLRQKLQSEQRVCESFCRSIEEYRRGIKEYEAMIESAQQNVALSKATVARLAQSLEEASERLTLFET
SPEPIVLSSEVLSVPQEKASV
>SEQF2545_AGK83762.1 hypothetical protein TPFB_0118a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MALQILLRTLTRGIQRGKTLIREHDRIVNTSPAYVQGTSLPLYPCKDRRPA
>SEQF2545_AGK83763.1 methionine ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MANQTLWLLVARATGQTSLMVCASASIALAAGTPLGILLCVMSPGHVWAHPAWHRVLSSSMNVLRAFPFVILLVVLLPLS
RMLTGRTVGTAAAILPLAIAALPFVARVIESALLEVEPGIIQAAVAMGSSMRQLVLKIMLPEAAPACVSGVALMVINLIG
YSAMAGAIGGGGLGDVAIRYGYQRFQPEVMTMAVLAILAQVALTQWIGRIICTRIRARR
>SEQF2545_AGK83764.1 methionine ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRLERLKKTYAGVPILRDISLEIPAHGMYGIIGKSGAGKSTLLRIMSLLEKPDEGAVFYHTTRVDLLRGAALRAQRRRI
GLIFQQFHLFSSRTVFGNVAYPLEIARYARKDAYARVLHLLHLVGLADKAQARISTLSGGQKQRVAIARALAAEPAILFC
DEATSALDPQTTQSILTLLKNVQCSLRLTVVLITHQMEVVRDLCDRAAVLHEGEIVEEGRVTQLFAAPRRLITQQLLSGC
SFASFAKSEPFHRMSSGACAVHAIDKAHW
>SEQF2545_AGK83765.1 lysine 2,3-aminomutase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAECTREQRKRRGAGRADEHWRTLSPASCAADALTEHISPAYAHLIAQAQGADAQALKRQVCFAPQERVVHACECADPLG
EDRYCVTPFLVHQYANRVLMLATGRCFSHCRYCFRRGFIAQRAGWIPNEEREKIITYLRATPSVKEILVSGGDPLTGSFA
QVTSLFRALRSVAPDLIIRLCTRAVTFAPQAFTPELIAFLQEMKPVWIIPHINHPAELGSTQRAVLEACVGAGLPVQSQS
VLLRGVNDSVETLCTLFHALTCLGVKPGYLFQLDLAPGTGDFRVPLSDTLALWRTLKERLSGLSLPTLAVDLPGGGGKFP
LVALALQQDVVWHQEREAFSARGIDGAWYTYPF
>SEQF2545_AGK83766.1 phosphoenolpyruvate carboxykinase (GTP) [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MELHEIAHARAKAWIEEMVALCAPDTVYVCDGSKKEYDTIMQKMVDAGLATPLKKRKNCFLFRSQPSDVARVEARTFIAS
KREDDAGPTNHWTDPAELKKTMTGLYSQCMKGRTMYVIPFSMGPVGSPISKNGIEITDSEYVVCNMHIMTRVGTRVLEAL
GTDGEFVPCLHSVGKPLGPGVTDAGQWPCADMERKYISHFPEERLVWSFGSGYGGNALLGKKCFALRIASVLARDEGWLA
EHMLILKITNPAGKTKYIGAAFPSACGKTNLAMMIPTLPGWKVETVGDDIAWMKFGKDGRLYAINPEAGFFGVAPGTSDF
SNKNAMDSIKENAIFTNCGLTEDGDVWWEGIGYPAKGTIIDWHGVSRPAPTRDKSPKGEEIAHPNARFTAPARQCPAIAS
NWEDPEGVPIDAFLFGGRRPSTVPLVHQARDWNHGVFLGSIIGSEVTAAVISDQVGQIRRDPFAMLPFCGYHMADYFSHW
IKLGSQARAENLPKIFCVNWFRKDAEGNFLWPGYGDNSRVLAWIFDRCDGVDNAVETAIGWMPKEGALNTEGLNVSTQAV
KELLSVDIAGWKKEIKDIRENHYPKFGARLPQQLRDALEVLEARINGSEGAACTRDMC
>SEQF2545_AGK83767.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLCIYVELPYYYQLTRIFPADIESLCARMRRFAVHNGAALHEASSVRIFAFEAHSLGSVYAAVRCVRALYQTLDTYEKQV
KEFRILMDVVADDASPCLIEDRFHAYRSTLIPDRGFFASFRAKQLLKHYLEFLPLPALNMYQVNGFLSLCAEKPFPQGVT
THCIVVRTTSSYMSALCNFMALHPLSEAVYSTLSEETRAFFFHLRAAVSFFKRRRYDSSFPQYLTDAFLQYVGLYFKLYY
EAAPNAPPPPIYVDPCAGHESQKQAEKVLIVSPHSPLMRLPASCADIEAIPQDLAEVMYTLSLASRYIFADEIEEFFLFL
KKHADFVGDLFDKMFCTQVTMVPHNAYAIPEDVHDSLEKRVRVKMPVIRECISSFLWKKYQEGSLCASTDLLRTFQELQY
KYTSDCVLHSLFHTYSDVQIAHLQVEEYTGTDVGAVLKVYQHTLLVGMREDAEAAFREAKACLTTLQARRFVSAEYRTFS
LLGFLTIGQSKFEDALVYFGYALDDAEQLRDGDFLCSALFHLSITYFLQHNFTQARLFLSKLSDAISTYFEQRWKTVSLF
MQGRISLSLGEYAQARRCFDEAADFALQYFEHQEPLCRVWAAHARLLADKSYAAHALFQDMCDQYPDAYLFLVESYVRAE
CFDDPTLFQSFPEETTSREPCVPSFSLDTPIYSGFSCAEDLVWGRQCAFAVSAQHSTVFAHYYHCRVHLHRAEDMQTFHH
HKQKLEAIARRAFQIGDPSAALFLYLCYDVSYRVHGAEAAVTTAHLSRAFKVMQRSVAYMSENTVRAQFMQDNFWNAKLF
AAAQANKLI
>SEQF2545_AGK83768.1 Obg family GTP-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVNCGIIGLPNVGKSTIFSALTANVVEAANYPFCTIEPNVGMVTVPDVRLEALAGHFRPKKTVYASIECVDIAGLVKGA
SQGEGLGNRFLAHVREVGVLAHVVRCFEHTDIVHVHNKVDPLSDIETVHIELALADLASVEKRAVRAQKESRMGKSLQKE
STLVLRALDTLREYLEMGKAACMAPLSDEERNAVRDMRLLTMKPHLYVCNTDESGMQYGNDFVRAVQEHARVHNTQAIVM
CGKFEAELAQLSDVAEQNAFLQELGLRESGRAALARAVYSLMGLRTFFTAGPEECRAWTIRAGLRAPHAAGVIHSDLERG
FIRAETYSFDDLASCGSVAKVREANRVRQEGKEYEVQDGDVIFFKFNV
>SEQF2545_AGK83769.1 exodeoxyribonuclease III [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGPVQRIISWNVNGIRAIERKDFLSWLAREAPDVLCLQEIKAHESQLSAALRAPVWSAGAGGTYYTYFHSAQRPGYSGTA
LFSKRAPDAVRFFGVPAFDCEGRMLAARFGELTVVSAYFPNAQEGGKRLAYKLDFCAAFRAFCDEERTAGQHVILCGDYN
IAHKEIDLAHPQENEGNPGFLPQERAWMDTFTEAGYADSFRAFCTEGQQYTWWSYRARARARNIGWRIDYQCVDQAFLAR
VTSSQILSEVTGSDHCPVCLTYAD
>SEQF2545_AGK83770.1 hypothetical protein TPFB_0126 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKQLKWWAVGPVLGICAGVWGAAHPVHADPWDTTAAGRSTIRLSAMGAVPLFQVDWCNSGRGDDRNANAQTNGHKYIYPA
FSAALGFEHFVCRGLSLGIDASVQYHCSYPNNTYSPTTPYYYLAIPVALTAGYTVAFWRIRLPLTVGAGFNYQHYYTSTY
YGLVLKAAAGCYFQLTEHWSLGVSATYSGVPRSCEKIIEEDRQQTNTRTAQFIAAGVDVRYHL
>SEQF2545_AGK83771.1 hypothetical protein TPFB_0126a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEGRILWVLRVWGSGQSVREGGDSAELGARQATREQQCSDREERDGALAIRRGMSLDLVENGMPVYYFAARAQPPAVAPA
NDILWDAGVHARPLERLHPSPSPARSPSPSHLLPGCSYNSTLSGDYARAAAAAGAGVDINFPVYGGVLHASQASNVFQGV
FLTDTTPMRTHDIPRSPLVGHKKNAAPDGIGASRACCPARENEPFKKGSTNSRGGG
>SEQF2545_AGK83772.1 hypothetical protein TPFB_0126b [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGVGLAQMKKENTPLLAVPGARGGFFLLGRRPCLTCPPRQGGIASFARGFPCLRFPALPSSDAMPRVPALTVPLTFAAFS
FLCPTSDCAVVLQHVIGEKYSPEYTRTVVTDRTLVRRRVGV
>SEQF2545_AGK83773.1 hypothetical protein TPFB_0126c [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGVDGHATHKMLAGGWAGGNRRAACVGAIPTISCLPLRRSSIVFLVRTAPVCVCARSASLLLGRPCLTCPPSRCEAGRVY
PSVRMSSLLEGLGATIFICNAPDAVVLLHGCGEKDTLKYIALLRTRNCSSRGNRDTLGEKTAPC
>SEQF2545_AGK83774.1 hypothetical protein TPFB_0127a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLGWGMDMSKSVMLCCLLSVQPCYAGYVFVSPKLGVYGEALGGPDTVGKAVKQADGTKIAPKIWYYAPRTPLFGVDIGYQ
ADNGLLFRVNLDAALTRLMFRSQCVVGYSLRFGWGGVRLYRFGNRV
>SEQF2545_AGK83775.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRHSRALCFAASVWWAIPCGSAGGGYVSIASGIECSATVDDAQYEPYTKNEQGTTVASNTVFPCTVLEALVRDPALTADY
LLYGMQSCYAIPLHVGVSYYLAKRWGIECALTASLGISMRTDVRVPYAVRIGPVFRV
>SEQF2545_AGK83776.1 hypothetical protein TPFB_0128 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEFLRATASREVDVNSGWGYGSGVERGFLCEGDVRACLVPASHFVRAGTAPGTTPGTAAACLFVPPYVLGVTPAGTLPFG
LPSQSVLGGLRLAPVHASSLLEGLGATIFFRCNAP
>SEQF2545_AGK83777.1 hypothetical protein TPFB_0129 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLAFDAGGRPTPGSGCRLGLGRGLLGLCNGQACTPASYKMSSAAAGTAAPARARAWNEVFCVKRMCARVLFLCSTSYQEQ
GLQQQLFCSYRRTCCGLLLLGRRPCCLCPPSAHLPCLMVPPSDAMPPTRLRS
>SEQF2545_AGK83778.1 hypothetical protein TPFB_0129a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAMTAHDCASLVGRKKDGAQGNGVGADCVNVEARLASQTCRGHCIRWWHHQAGKVRTGRAKTARASSKQEQTTARTAVRT
KKLLLQPLLLVRSGAQEQDTRAHPLHTKNLVPRPSPSRSRSASRSRRHLIGRRRTCLSITKS
>SEQF2545_AGK83779.1 hypothetical protein TPFB_0129b [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MERGFLCEEDVRACPVLVLHFVPGAGAAAAAFLFVPPYVLWFAPAWTTPLLSLPSQCAPSLLDGATIGCNAPDTSEKLNE
PPHSRSPRLRHCPALRLSYAPRGWRSRVRSWPC
>SEQF2545_AGK83780.1 hypothetical protein TPFB_0130 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRPPASEASNVFKDVFLTNAMDMQTHDCARSMGHKKNGANGDIGADCVSVETRSASQAMPWALHLKLVAPEPSGKEAHI
KGQTRPASYRLGGQRQSGQGPSRNSQHVRRYEQKGHAPCCSCCSYEVEGRILLSMPARK
>SEQF2545_AGK83781.1 Tpr protein D [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGKQVMQAGVLAGMVCAASGYAGVLTPQVSGTAQLQWGIAFQKNPHTVPGKHTHGFRTTNSLTISLPLVSKHTHTRRGEA
RSGVWAQLQLKDLAVELASSKSSTALSFTKPTASFQATLHCYGAYLTVGTSPSCVVNFAQLWKPFVTRAYSEKDTRYAPG
FSGSGAKLGYQAHNVGNSGVDVDIGFLSFLSNGAWDSTDTTHSKYGFGADATLSYGVDRQRLLTLELAGNATLEQHYRKG
TEDSTNENKTALLWGVGGRLTLEPGAGFRFSFALDAGNQHQSDTKFYFRMAPSQRVHEVINSLGDTLLTSPQQDVVSFFV
QELSKGSLLEKAGLVTLLAQRTIVGLASSGGYLRHLNGKGLEINMRLIEQQKNPDARMRTALFISWLQFTYTKTLNIDAL
LGMQWRWLSSGIYFATAGTNIFGERVFFKNQADHFDFAGFLKLETKSGDPYTHLLTGLNAGVEARVYIPLTYIFYINNGG
AQYKGSNSDGVINTPILSKAWCSYRIPLGSHAWLAPHTSVLWATNRFNHNQSGDALLREHALQYQVGLTFSPFEKVELSA
QWEQGVLSDVPYMGIAESIWSERHFGTLVCGMKVTW
>SEQF2545_AGK83782.1 hypothetical protein TPFB_0133 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMARSRCVHRVVHQAACIGVIGLSTSALTTCDFTGIFVAIQSEVPIKTPSIPGAIYGLVKAGSKLYATNGQLWKKNVAEE
GKDWERESCFDSVIGDSRITSLAADNGENGVLVACILGKGAYKWSQGSADQTSGNPSALSGTEKALSVVGTGTSCVYLNH
TDDKVGETSSSESGGMTASGETNEFCLHAGNGFLVTTKKVCVGSDGSPVAKSDGEEPVPPILAATDDGSGHVYILTKDKV
YCKKVNQSEGKIQDCPQSAAAAPAPTGAHSVAHKVADAHSIAFFKNGSDEFLLIGGRQGYGEIKLERGSGSNGNGAQCVH
LKEENVHDQTGWHEKGSTPKDGAEQYRSTIGRWAVSGIYVIKKGTSGGRKKRSTSTDCERPDLYVAVGDASDTYTGLWKF
DTTTCSWNRE
>SEQF2545_AGK83783.1 putative outer membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCKPRVWRIAHTIVHVGALLLGTSQLTTCDFSGIFATIQQEVAIKSPSIPGAIYGLVKAGGKLYATNGRLWEKDLNDTKW
KPVPFLDGQDKRIDSLAASNTCVFACVSGDGVYKYTAGTTSSQKESNTDKAQAVVQMSDGKVVLQCALGDEKTTPSDADE
RLLGGGQGYLVTSKGFYTLPGSASCEVISETKDVTCKAEAPILASACDGSNTYILTKDKVYCRYTNGSGSTPTTWCDVEH
KVSEPLALAVFKNKGETFLLVGGQQGYGEIKIATASGSSSSSSCVPLTAENVHATTGWGANCSTPEGSAEQYRSTIGRWA
VSGIYVIKKDTSGGRKKRSTSTDCERPDLYVAVGDTNDTYTGLWKFDTATNTWNRE
>SEQF2545_AGK83784.1 hypothetical protein TPFB_0134a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVWAMRHTRGLHIKPPRREKTPPRSECYRRALGMQRWCAGRDPPAKKELDKCWPGGGRILEGCVGCPQLFERCGAKKRMK
QLKQCAAHGIRFLQVCACGVGVAAGAAYAQEVAPAASWDVTAAGRGIARVSFIGAVPLFQVDWCNTARGDLGALQPTGIR
KFTPRLGCLLDTSILCIAACRSGLMRARSTPAVIRSITRRSGCVPTLPFL
>SEQF2545_AGK83785.1 hypothetical protein TPFB_0134b [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MWSEKTYETAKTVRGTRDTLSAGLRLRGGCCRGCSVCAGGGACRIVGCNRRGAGDRARFVYWRGAPFPGGLVQYRPRGSG
GVAANGNKEVYPAFGVSFGYEYFVYRGLSLGIDASAQHSCSYPFYYQKERLCSYLAVPVTLNASYTLAFWRIRLPLTVGA
GFSYQHYYTSTYYGLLLKAGAGCYLQLTERWSLGASAAYSGVPRSCEKVVEEEREQTNTRTAQFVTAGVDIRYHL
>SEQF2545_AGK83786.1 putative outer membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRSTMDTQYMRRRVCTVVRAVVCLLSTSLLTTCDFTGIFAAIQSEVPIKSPSIPGAIYGLVKAGSKLYATNGQLWEKEL
NGTGSWTKVSSSSVPTDSDKKVMSIATDGNTFVLACVPGTGVYKHCVNGSGSSSGTTASSSIETCSNHATLVGGTSKPFW
LVPGDTGNSANGGGGGGGCGSSSSSSSCIRITDSSSSSCIRITDSSSSSCIHIKKEDTGEQFLDMGEGYVVTTKHLYTKN
GSSSAGQAPCPGGGGGSSGGGGSSEYTKDSCSFSTPILASVSDGCYHYILTKEKVYCRKQNAASSAASSPAQCPSSPSSS
SSSTNAGCEVAHGVEDPLCLAIFKHNGCEYLLIGGRQGYGEIKLEARSGDTNGTCKRLKESNVHKSPDEWDESSPTPKAN
AEQYRGTVGRFAVQKIYVVEKNGGGSSGAAGGAGCPASAGSTSGGTSSTQRPDLYAAVGDTNDTYTGLWKFDTTACSWNR
E
>SEQF2545_AGK83787.1 hypothetical protein TPFB_0136a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVSPLEKVEIRLSWEQGKLQENSNVVIEKNVTERWQFVGAVPRWVCSREGQGFVRSGLLRNIH
>SEQF2545_AGK83788.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQPPRPACQDEGTHGKEVCMLLIQKKRLLVVLIVSFLSILFSAGYAFRIGMLHAHKGSAETILFYGFVAAAFHFILSLYL
MLHAHHKKKELLKLADMLRYGGSIGESHFKKFGVLGTQIQFLLKELLALSAQKSLKIAALSGLQRALTELIPTPVIIIDL
NGTILDMTKGARKRVQRADKTLTIEHIFPATDSTRAVQEAEKTHTPVEQEGGIVFIPVFSAVGNISHFLVDISKQPASDE
PLSLA
>SEQF2545_AGK83789.1 Trk family potassium (K+) transporter, NAD+ binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVKRNFAVVGLGAFGYRVCEVLVQGGGSVVAIDNNAQTVEKVKKVVSVAILIDTTSETELMKAPLDDVDVAIVAIGTNL
QASILTTALLKQRDIPYILARATSPIHETILRKIGANEILNIEVASATTIAKRLVAPDVTDAIAMTDDISLREIVAPRFF
TDKTLEELELREKFNVKIVAVVRTDMDIDPTGNSLPKKNIYYPDNAFTFRRADRMFVLGHNRDLRELTQI
>SEQF2545_AGK83790.1 Trk family potassium (K+) transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRPMHIGNLTHLTMLVLCLAIRLCDQFLPFSVQFFTIVGDVGILVLVWSSLASSLNKEKYVRTFLRQYTVPVFLGLLITL
LTFVRASVTLTTASGDLYTTLTHIQNITLGIFALIAFKAQKKFAERAVSNPSQMLIVSFLVVIFIGTHLLMFPGATSHSQ
PLPMLTALFTATSAVCVTGLSVIDVATQLSTWGKAILAALIQIGGLGFMVFSFFGMITIKKKMSLESRLVASHLVSDSDM
GSLSHNLKLIIFSTFFIEALSALFLFVGFSQTEGYTIQSLGNAYFHAISAFCNAGFSLYPNSLESFVSNPWITFPIAFTI
ILGGISFVVIDEVLCRVHGSIKNIFFKGKNILGSLSLNTFVVLKATVLLLAVSFVGIYLLEHTHSMKVYQVGTQYLAAFF
QAVTLRTAGFSTIPFSNLRTATLFFMTFIMFVGGASGSTAGGIKLNTAAAIIASFRSFIHHDPKPRIRNLVIQGKQVERS
FLILGFGICTVCLAGFCLSLTDNIPFIYLLFESVSAFATVGLSVGITANLSTAGLMILLILMFTGRVGTLTILTAASKEE
QDMSVEYACGDLAIG
>SEQF2545_AGK83791.1 hypothetical protein TPFB_0140a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHRHCLSLSPSTNTDILVFQRKTTSDLYDLCVLIVFVYAYELARAPSLYRQRLELS
>SEQF2545_AGK83792.1 methylated-DNA--[protein]-cysteine S-methyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSVHQGGIRFPLLYLEMETPLGRMCIAERAHTIVYVWFHRVGPRGSPVSGVCAQHVCPGKTALLRETQSQIHAYFCGALR
EFSVPVTVEGTPFMQRVWGATRNIAYGTTKSYAQLSQDIGCPRAARAVGQALHRNPLLLLIPCHRVISARASIGGFAYGS
ALKHFLLQQEAAVCACE
>SEQF2545_AGK83793.1 putative sugar ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDNRPYVVVQELTKVWEEKRISLSFSLRQGTSLALLGASGCGKSTILKMIAGLITPDHGSVFIAGTNVTHWAPARRRIGM
ICQDFALFPHLSLEDNIGYGLVSQGLTKKTARVHAREWMARFGLQNMETRSVTTLSHGEKQRVALARSLAVRPALILFDE
ALSAIDADLRTTLQGELRALQRSLGYTAVYVTHDSTEAAALADTVIHMRTQPPLAAAKNA
>SEQF2545_AGK83794.1 ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPRCSSGITRINPMTTLLHPCRRSCASGALYLTRGRDARNYCVALICALCFSLSIGTFLIPVFTAGSAFFSKPRLENTAA
HPSPGALQTGSPITPFFFPPGTPGAARFGALFAQSVFQALCSAVLACAVGFGAAFFFVKRSLRARALFPALCAIPLAVPP
LTMALAFLLSFGKNGLCTRTLGTLWGVSTPRTFLYSASGVVIAHAWYNFPLALAIIARAWNTISTDAEDAARLLGARAYR
VFYTITLPALAGALRSSFLVIFLYCFFSLMMVLLLGGTTFTTLEVELYRSIRTQAAHPYASTLALSQTFYALLMIWGVST
EESQQAQSCVARTRPLPTQSIQGNIERIGFFALLCGILFFLILPLFSLVLHSITRHRAGRTVSFTLTAWHTLFSAPSFWH
ALRSTIWIGFWSFCVTVGSVLCYGYMVLMRHVSRWKTRLPFLPLAVSPMVLAFGWSLMPRCASRILLVCAQSALAFPFAW
LSLYSTLMRIPTPVIFTGQMLSRNRLDFFLRTICPLCKKGIVSAGVYAFALSAADAAFPLVLEIPDFQSVALLLYRLSST
YRFAESSALALVLSLASSVLLIGVHRCKEYSYG
>SEQF2545_AGK83795.1 thiamine ABC superfamily ATP binding cassette transporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAHRMRVVFCCAAALSLCCCSRSRTDAPSLVIYVYDSFASEWGPGPELARRFYAKTGYSVQYVVFEDVTRAIHRAIRDQH
TPSSRGADLIIGVDQYTLPLAREADLFSPYQPALPLPHALRIDPHNLAVPYDWGYVAFMFNTDAALPEPQRLSDLANPVY
AKSIALADPHTNVLGTIFIGWAHTSLGAAWPAFWNTLYRANLLALAPSWSAAYGLFTAGEAALVLSYTTSAAYHLHHDNH
TRFKPLLFPEGHPMHIEGISLVKRTKHARVATQFIDFLLSTEAQELLPLTQWMYPANPDVPLPAAFSAVPQPAACVSLSP
QMCRAAAAALHASTP
>SEQF2545_AGK83796.1 long-chain-fatty-acid--CoA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLKGSAFGTLARMSVCCTSSEERIERSKNLVHLVAQVAGAYAQLPAQYAKSSSGVFETTSFSSFYEHVCLFAAGLASIGC
GRGDCIGLISDNRVEWLHASFGIQALGAADVPRGSDATERDLVQILGAVEARTVIVENDAQLKKLARCFDALPSVSQIVL
LDAGGAYQAMKDEFVQNEDGSARKCSFFTYQDILAHGTQFRVHHPGRIEDEIGRTTRADVATIIFTSGTTGTPKGVVLSH
ENFLCQLIDISRRLTVCPGDIALSVLPVWHVFERISEYVVLSHAGGVAYSKPVGSVMLADLAKLNPHFLPSVPRIWEAIH
DGIFKNVRKKGGVAAALFHFFLAAGKAYAYFYRSVFGLRTHTTRRAQFCAPLFACVPWLLLVPLHFLGNVLVFRKVRKKF
GTSFKTAISGGGALPPNVDEFLYAIGVRVLEGYGLTETAPVIAMRSERRPVFGSVGTPCAYNEVKIVDDTGAQLPVGYKG
IVLVRGKNIMQGYYKNPELTAQVLDADGWFNTGDIGYRCVGGQIVLRGRKKDTVVLRGGENVEPVPLEMSMQESRFIARA
VVVGQDERYLAALIVPDEAELRLWAEAQELRTECMEELLVNPAVVKFFEQEIAKRISLENGFKIFERINRFVLLPKVFEV
GVELSAKQEVMRHRVADLYAKEIAQLFS
>SEQF2545_AGK83797.1 glycosyl hydrolase family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKGDNTKIRIAFAAKLTGACVQSLHAEHDPSQYQAFFSGLCRHEQLPLTVHMTGSFFQFIQKKNSPYPYLINNLLGSKR
LELLSGGFYQPYLPLLPQADVISQIELLTSTLREHVIKRPRGCFLEASAWSAALIPSLVKAGMEYCLLDYRLFEASDMPA
TKPAVLEDSSKCLVALPYRELTIDTPAETFYAQLVARYGDTPGTVLIFMLPLDCYQKLFFTHDNASTWFKTFIQYVQKPN
SPFRLTHTGEIYKEPPVCLGYIASNMVRNDVLLHKTAKQLIICSTHARLLYAKMMYVHNIAMQIKGDKQRKHHALSELWK
AEQGVFFISSDRGYASAGSAQRTAYKYLLTAEKVARTPGVFNNSLITFDFNFDGVREFLSQRELMNMYVQLPGGLIFEFD
IFSSYKNYAAVPRQPGGIFIDYVLSEQDVVHLRENPGHAVPTVFSHTPYQEIGFDPIKHELTLRAEGIFEEFNQPVSLKK
QYFFKSEGVQVQYILKNESPLNLSAFFAVEMNLAVHGTDDAAPELVVFSENEKYTAAITRDHFPCISWMRLTDPEGKTVF
TIEGNENPDVAITPLCESTSNQYANTEGIKCLFYWKVDLNAGYETEKMLFLKAFSTKKR
>SEQF2545_AGK83798.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVTMVPPLFFVCALFFAEGIGLDRLCIAALSPRCTLFHTCRFLFLGGILITGNWVCIHYVYDPLALRFLTPLGVGASAFC
LSTCSGKLSRTCTSHRAQSEWGLLYALVFYITYTALNLFEALVMWGVSCVGFLCFSTVLRAIHQRITQGNGTAVEKTAAL
LLASMGFIALSLYGTDELWLFPIPAAGMRTRL
>SEQF2545_AGK83799.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSKYTVKRASVLCIFGIGLFVPATGTFACGLLLVLGFWVLFFSSLLARFLSQFFMRTRSAPLFEVCLTLSAAIMYDNLIQ
GFFPLVRMMLCPYLFITALSRTLDLCLTAYDADAESLECVGVFGIMIAGISLVRELVAFGCVSLPAPSGFLRIISFPPSN
VIRFAATGAGTLISCGIVLWIFRSAGNDHTPSLRSEW
>SEQF2545_AGK83800.1 hypothetical protein TPFB_0150 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCGGVAMTYNTNTSLSSYAGLSAFALSVFCILWGTARTGSFLKEKALITCAADILARQAPELGVTSRTLRMVPSSPIPQA
EVLRGKKNTGEEIFLYFFPLRGMYGSFPTLFLYDKKDGARFCHLIGNHPTPRDARFYGISSARIALQCRKIEHLHQTVAY
E
>SEQF2545_AGK83801.1 putative NADH dehydrogenase (ubiquinone), subunit RnfD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRTAEYKHAPFLYTGLSAGQNNSVLLALLVAHVFVVAAMRDTVALFSIVSTELGALSAALVQTLRTPHVPLSDSLVLGLL
IGAVLPAHNSFLNTFCVAFCAVFFTRVLFGGKIGNWLNPIALAPVLLRLCTEGTSLPTSGRVSVVQGAMSYPLFYSALVE
WDAAVRTWCNTQVFQPLGLTLPEGALSACVFTQAAVPGFRYPVLTLLAALCVYAVRARRYICSCAFLVVYSTLFFLPAHA
HPATLVSLIKSGALFTAFFVLPEPDTSMRTNGGAWISGGLCAMCAFFLAKKNSSAPDMWGAHDMHLWSAILLTNIVQPLI
LRAESWYYYVRRRRYDVQH
>SEQF2545_AGK83802.1 putative NADH dehydrogenase (ubiquinone), subunit RnfC [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIERLRSSRGKLTLTHQIFPLSFGGNAFLPARALVPFSVDAGEPAAVAVVKVGDTVREGQLIARAAHAGAAHAHASVPGV
VTRLVSANFLAGSALRAVEIRTRGSFEHLGKVQPNRPWQHSTASELLRLVTDAGVVATRLHPHAQITSTATGTHAGAQHT
YAKDYGQKRRAEAHTLRLMRAAWESGNALATHLHLHVRKGVRKLTLYLCDDDATCPLSSFLAQEFPEPVATGTAIIARIL
DATYTACLHTLPKRSPGLARMRAVFPFNEMHDAYRRHYPFSNLSAPRYRAGCTIDALTAVHVYEAVVLSQPQISSYIALT
GAGLKSPQVLRARIGTPLGALIEECGGFRTRPGHLIINGLLKGSVLESLDLPFSKGIKSLHVTGKALSSSASCTSCQNCG
DCARICPVYLDPIKIARAAHRNQFTEEVLQSLRICHQCGLCSAACTARIPLAKLLHDAQERALHLSRAPVTKIEPHSTQS
VGKTIREAPANAHR
>SEQF2545_AGK83803.1 hypothetical protein TPFB_0152a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSLRWTCMQCGGPLHTEEEAVLCAFSRVSLPRREAQTFSVPYRGHTNDRAPTEQSRETHPHPPDFPPQLWGECFFACARS
RSVLR
>SEQF2545_AGK83804.1 putative phosphatidate phosphatase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDGGYFLGQLHAVFSGEVFLSATCSWLASQVIKVAIACRRSAIRSVHGFFDFAVWRTGGMPSSHSALVSALTLSFALKCG
LHSDLFIFSFFSAIIVVRDALGVRRSSGLQAEALNSLGARVSEKLDFSFRPVREIHGHKPLEVVVGVAVGIVTSALFYSS
MSP
>SEQF2545_AGK83805.1 pseudouridylate synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCAILGRLYPPWAVVSYWERRGGRLGGATGIRHGDAPCMKVGVRRVKRWVSSNVPHTVHMDVVPPVSTVRPHGGAAVECF
RCTKNDAGRRVDRVLRILLPACPRVGVYAALRRTAIRLNGRPVQPAKRVQVGDVLSLPESLCRARAASSRLSKMPGTPKL
RVLPSVVFKTQDLLFFHKPAGLCVHGPRSLDAWVRGQGRAHVPPALSFRPGPLHRLDRGTEGLIAFSRSLRGAQWFSAAL
QQHTLRKFYLAITAAPARTAAAARTLVRPGEVTHVQTVLHSCDSALVLRVIVPVTGKKHQIRRYCAAQGFPLVGDRTYGG
ASQHGNARYTRFFLLAWCVRFPSSRLQALPAQVWTTPSPAFMRVLTSFPPDSLARARACVDALDGALGTDATCPQDTAVC
TPEG
>SEQF2545_AGK83806.1 M23B subfamily peptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSVYCRSSKQTVREPCRPVPVGALLLFVTLLLLALALAYFGAQVEPLTPALTLTEQEPRQASGYVSSLLRARIVQEDAEP
ALYYTVYEVREGDVVGRIAQRYDISQDAIISLNKLRSTRALQVGQLLKIPSVDGILYTVKNGDTFSSIAAAHQISLERLV
LLNTPSSSNESPPSVRTLVSPFYNSAARESCVPFPFSSAKQWRENTSFDAVQPLQPARVLFLPGAHLSARALQEINGDLF
RAPLRSRYYVSSRYGWRSDPFTGARSFHNGLDMVSRRGTPVYSALGGIVRTVGYSAVYGNYLIVGHHAGYQTLYGHLQTV
LVSAGTRVTSATKIGLLGKTGRSTGPHLHFTIYKNGSAINPTSLLRMRTLP
>SEQF2545_AGK83807.1 putative 4-hydroxybenzoyl-CoA thioesterase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNFSLEFPVRSYELDGYGHVNNAVYLQYFEYARAAFLLHIGFDLKQLHEAGYAFYVTQAHIHYRTAVHLFDTLRARVKPL
KLGKASGVFSQTLENQHHVLCADAEITWVCVSRTSGKPTKIPPEYLVPALYPNY
>SEQF2545_AGK83808.1 putative phosphate acyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSIHSLQQTFSDIVPLLEQYTRADRFMREDNLLHERNEPIRRIVESLVARILLPGSTMRGNEQIASFLHKTNEGKRGLIL
AEHYSNFDLPCLLYLMEQGSSAGRMLSEKIVSIAGIKLREENRILAMLTEGYDHLVIYPSRSLATITDAHCLARETKRSR
ALNRAAMKYLEELRNAGKVILVFPAGTRYRPGRPETKRGVREVYSYIKHAEVLLLISINGNCLRVAERSTDMTEDAVHPD
VVLLEARTVDDCALFREKALDWHRTHNVAAPSEDKKQIVVDYVMHLLEEMHEHNERERLS
>SEQF2545_AGK83809.1 HAD-superfamily hydrolase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLNWSIPVIRHILFDIDNTLYSCTNPIEMAITQRIHTFVAHFLHVSCEEARALRQRTKHLYATTFEWLKAEHNLIHDEHY
FRAVYPPTEIQELQYDPMLRPFLQSLHMPLTALTNAPRVHAQRVLDFFHLSDLFLDVFDITYHAGKGKPHHSCFVRTLEA
VHKTVQETLFVDDCLMHVRAFIALGGHAVLVDERDCHAELPPSARMTRVKTIYELPAHLARLAQGDNQ
>SEQF2545_AGK83810.1 hypothetical protein TPFB_0159 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYIKVALVCLFSMGARCLLATEPAPVSGDYVLYRDYSWKSPTWVGFLCYDAHTYGALLCTPAESRRITILFTGTEKHGRF
ELTGQRITSPVRTEDLTGINYLMDLFPQLQRWKHFPRDTHTLVARHTDRSKKSTQFSGAVELQFASFVPLFHLEILRDKQ
QRVMLQLSEIGKIDHTSDAAFFQFTPMPPSTPTDAPPATLNQTLTRTEYVIDDVCIALDPQWKRIAENSFLSDFAFLTVH
QVPAPRAHDYSALRALLQLFLYSGPQGKNILEQLHINDTHARLTLSYAVFDLPSKTVKKTWKIFIRHSDTHYSILSLTAD
QRTAQRYARYFDTLIETIRTKN
>SEQF2545_AGK83811.1 proline--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKMSAFFAPTLRSAPADATIASHQLLMRAGYVRKIANGLFAYLPLGLRVRHKIEAIIREELEAIGCLECTAPVVTPAELW
KESGRWYRMGAELLRAKNRLDHELLFSPTAEESFTALVRGDCTSYKHFPLSLYQINAKYRDEIRPRYGLMRAREFTMADA
YSFHTDCACLARTYEKFAHAYRAIFRRIGLSVIAVHAHLGAMGGQESEEFMVESAVGDNTLLLCPHCTYAANCEKAVGQR
PLPDTHDTHLKDEHEGSDLKTPAAMREVHTPHVKTIEELEHFLHVPAHRCIKTLIYRIDTVPQAAGHFVAVCIRGDLELN
ESKLEALLRVPSVVLATEQEVYALSGTPVGFIGPVGLAQRAAAAYAARTPAFFPSAAEPASVTSDIPFFSLVADQSVMAM
HNAITGALKVDTHLVQVEPGRDFVPDAVADLMLVRAGDRCIHCGAPLYEKKGNELGHLFKLGDKYTRSMHLTFTDEQGVR
QFPLMGCYGIGLDRTLASVVENHHDTRGISWPLAISPYAVVLIPIPHTQAPYAAAEALYVQLRTRGVEVLFDDRAERPGV
KFADADLIGIPLRVVLSAKTLPRVECTTRCGAHTYFFTQEEASEHIARLLEQLASPESS
>SEQF2545_AGK83812.1 crossover junction endoribonuclease subunit B [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDHTASLSPVRPEAQPTDDRERALRPRLLKDFLGQEKTKRNLRLFIQAARDRNESLDHLFLIGPPGLGKTTLAHITACEL
GVECKVTGAPALDKPKDLAGILTALSERSVFFVDEIHRLKPAIEEMLYIAMEDYELDWVIGQGPSARTVRIPLPPFTLIG
ATTRAGMVSSPLISRFGIVERFEFYTPEELAAIVQRSARLLDITLDARAALALARCSRGTPRVANRLLRRIRDFAQVAGS
AHISETIVRAGLAHLKIDELGLELHDIQLLRVMIEHFGGGPVGAETLAISLGESPETLEDYYEPYLIQIGLMQRTPRGRM
ATARAYAHLGLPVPEARTLTPHSPEQGTLL
>SEQF2545_AGK83813.1 iron (Fe2+)/zinc (Zn2+)/manganese (Mn2+) ABC superfamily ATP binding cassette transporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRERICACVLALGMLTGFTHAFGSKDAAADGKPLVVTTIGMIADAVKNIAQGDVHLKGLMGPGVDPHLYTATAGDVEWL
GNADLILYNGLHLETKMGEVFSKLRGSRLVVAVSETIPVSQRLSLEEAEFDPHVWFDVKLWSYSVKAVYESLCKLLPGKT
REFTQRYQAYQQQLDKLDAYVRRKAQSLPAERRVLVTAHDAFGYFSRAYGFEVKGLQGVSTASEASAHDMQELAAFIAQR
KLPAIFIESSIPHKNVEALRDAVQARGHVVQIGGELFSDAMGDAGTSEGTYVGMVTHNIDTIVAALAR
>SEQF2545_AGK83814.1 hypothetical protein TPFB_0163a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLRWLASVECRVEWVEEPLVVGCTAAPVHDVVISEGGGALTADGSYPIERKEGSSIWQRYQQQLMLSRLTT
>SEQF2545_AGK83815.1 iron (Fe2+)/zinc (Zn2+)/manganese (Mn2+) ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAEISATAYAVQVDDLTLAYRQKPVLWDVDVRIPEGVIEAIIGPNGAGKSTLLKAIMGLLPLASGEVRVFGRPFSKERRR
VAYVPQRSAVDWDFPTTVFDVVLMGSYGLLGWIRRPGKREKARAREAIEEVGMGAFLDRQISELSGGQQQRVFLARALVQ
DADLYFMDEPFQGVDAATEQAIVTLLKTLKGRGKTLLVVHHDLQTVAEYFDRVLLLNVRVIAEGAVVSAFTEEYVQRAYG
GRISSTLFPRGNKEDVHDARAHASVL
>SEQF2545_AGK83816.1 iron (Fe2+)/zinc (Zn2+)/manganese (Mn2+) ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHALMRLFSDYTLQNVVLGTLFLGLGSGLVGSFAVLRRQSLFGDAVSHATLPGIVIAFLLTGTKSTEILLLGAALSGLVG
TVVMLMVMRTTKIDTDGAQGIVLGVFLGFGFLLLTHVQKSPQAAKAGLNKFILGQAATILQRDVLLIIAMEVVIGLLVLL
FWKELKLSTFDRDFSAVQGFSPQLMEFMLTALIVVAVVVGVQAVGVILMSALLTAPAVAARQWTNSLRVLCALAALFGGV
SGVSGSVVSAQVPRLSTGPVIVLVLTGIALVSIMLGPQRGVLYQLWRRRRVSLLQEEG
>SEQF2545_AGK83817.1 iron (Fe2+)/zinc (Zn2+)/manganese (Mn2+) ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTMEVVLIAVVVSVACALCGVFLVLRRISLMSDAISHSVILGIVLGYFLSRTLSSFVPFVGAVIAGICSVICAELLQKTG
MVKSDAAVGLVFPAMFGLGVILVSLYAGNVHLDTDAVLLGEIGLAPLDRVSFFAWSLPRSLVQMGSVLCGLLLLLALFFK
ELKISTFDPVLATSLGFSPTLINYGLMLAVSITCVGAFDSVGAVLVIALMITPPAAALLLTDNLLLMLVLASLLASCASI
SGLFLAVKIDGSIAGAMATMAGVLFALVYLFSPKHGVVRRCLVMRALKLDLDVVTLAVHLATHRYTVERSVECAEVHLTE
HVSWSARRAARVVRTALRRGMVERHGALLLLTAQGVSLAQARLDVSV
>SEQF2545_AGK83818.1 iron (Fe2+)/zinc (Zn2+)/manganese (Mn2+)-dependent transcriptional regulator [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSLVSDIAAENYLKTVVKALARSRRERVGTGELSRLLHVTPGTISTMVKRLEKGGYVQRTHRLGCTLTRKGAVFGSAVLR
KHRLLESFLSQVLCLEAGVVHKEAEMLEHACSDELIDVIDRYLQYPTRDPHGQPIPRKDTLLDLYVEDDVPGV
>SEQF2545_AGK83819.1 phosphoglycerate mutase family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKLVLIRHGESEWNRLNLFTGWTDVPLTPRGESEAQEGGRVLQEAGFDFDLCYTSFLKRAIRTLNFVLQALDREWLPVHK
SWKLNERHYGDLQGLNKTETAQKYGEQQVRVWRRSFDVAPPPLTVGDARCPHTQASYRGVCASGRTPVLPFTESLKDTVA
RVVPYFEEEIKPQMISGQRVLIVAHGNSLRALMKHIESLDETQIMEVNLPTGVPLVYEFEADFTLCGKRFLGNEADVAAR
AQAVADQGKSN
>SEQF2545_AGK83820.1 nucleoside phosphorylase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTVGVFAALGEEVARVRECLGGVGTERAGLTFYVVSVGALQVVYVCGGVGKVNAALCTQLLISEFGARVLINTGIAGALD
ERLCVFDVLVSVDAVQHDVDVTAFGYQKGRIPRMDSVEWTANTALRYLVREAFDLCTRDPEWTEGACALSGSGDPPSRVS
RLVEGRVASGDLFVSDAQTRARIIREFGAHGVEMEGAAFAHVASVNGVPFVIIRCISDGAGAEQDVSMSYKEFSTRAARR
SALLTLRVLERLSALRTSVVASLFPMVVV
>SEQF2545_AGK83821.1 lipoprotein, 15 kDa (tpp15) [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGGLCRCIPSCYTAALGGFMVKRGGAFALCLAVLLGACSFSSIPNGTYRATYQDFDENGWKDFLEVTFDGGKMVQVVYDY
QHKEGRFKSQDADYHRVMYASSGIGPEKAFRELADALLEKGNPEMVDVVTGATVSSQSFRRLGAALLQSARRGEKEAIIS
R
>SEQF2545_AGK83822.1 GGDEF domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRTCVRAYAVFAIAIMVLTVAWFAFSISQAIQRNTVGAQQRFAQVIRRIAPRVTSKRQLTDAEADFIQNLCKNDDLIMA
LNIFSNRVQLFSWTYDDLMFVAGGGSELVPRSSSLFIKIFSGRVPYQAKDECLLFTAALRVLTPANIFFRGCVVFLVMLT
LTISSMVFLVIEYLSVRRFQCAQGDARPRPAGPQGTARSRTDEAQVSPGTPPECQCPSFETHGQDLASKESVSDLEGLHL
YNHSDEELFSIHDSVFQEHTGGEGRMSSSSGEEGCGQTLLPVHEKKSTYGLFNPLTGVGWRAYLEERLEAELGRATASEQ
DLTLMIVQVEHPAHQTAVADAAKKLVEFFKFRDMLFEFEGSCCFAGIVQDASLEEAMVLARDIHKELCGAIESARVLIGI
ATRTSRLTTAAHLIEEAHASVKRAREDPAHPIIAFEAPHQCGRPYRSSAYRDVPDRSTC
>SEQF2545_AGK83823.1 hypothetical protein TPFB_0174 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTNVFKKNIRALRMRYQDIALTLERTHSNGIYAGTLTAHTGENIPFFRNNRTLHSRYNPWIEAERTLPAQPCFILFCGIG
AGIHISVFLEKFRHACCAVCEFDYASFRALLEQVDLTHIIVQERVHFLHPLTHGSASQEIAQCYMPIIHGNFFVHYLQPW
KAFFPTSEQKIAELTSQAMKIIRADFSVQVHFGKLWMRNALLNLRYAQIFTPKLPNINTQTEAIILGAGPSLEKGIEKIR
SHRDVYTIFACDTAFPVCCTGGLMPDFFISIDPQYISYAHTMCSFPSQVTAIFDICACPCAVRSFYLNGNSLIFTGGGHP
FSVYASRFSSLPFLETSSGTVAGAAYSVASFLGFTRITSVGTDFSYTNGKPYARGTYLSKQFEQKILRISPLETQFCNLM
FRTPTRQDNTQGGITYSNEILDQYKRNFDQITPGARPWHAADFRAFPYKQFINFFHAQLRSKHAAALLAMLPFITWYKTK
RTPQAPIFRILELVLEDVLRYTRYNE
>SEQF2545_AGK83824.1 hypothetical protein TPFB_0177 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSLNLHSKYNPRREAERFVAAILEGRRIVVITEPGESYTAEFLRARFPHAKLIAVRYTNDAFTSSDIQWDAVWRPDCGSL
HSFLINHIPDELLGQTAFVPWEPANRIWRAQAQSTWQEITYTIKVIQSEIATRIYFGKRWLLNTLRNVFFLERPVRVCLT
APEVLCVAAGFGLEQITRVGLPIVAVSSALQALLYRNISPDICMSTDGSFWAAEHFPPAPTLPVLFPLEACIPPRVFKYS
PISLLNYHSHTEHFFLQHLHIPSVSAQRHGSVMGTALEYLLQCGVHSIYLAGLDLHPGKGFQHARPHASFKRFNPKRTEP
LATCIAGNFDNRSLETYAHWFYSLPQEKIQKLTRLNTEHAPPSNVRTITYEDFSQHAFAKKDTFTFSEGPPISRIHKKAV
LRHYFERITRSAHHARIASSIASSGIEKEAFEFLAYAELLHLRKNPSQGTQTLIHKVRHEIVQLRNKLSI
>SEQF2545_AGK83825.1 hypothetical protein TPFB_0178 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGLIARASRIRRSSGVSCEYYRLELQFVQLVESLGIPRAGFLFLTEERMFDLRFPFGIDTTTFYRMRVPTSLLSPGLPAE
QWTTLFRQELTELQGYFSSHLFSTLRALHLYPFSAGSVRVYLVLFDTRTDVEEGALAADLHGDASGEERVRSFILAVQAR
FSFIEASRPVYPRQPELAPSCSQLEFALNNQRMANLFTISINQSALPPAVLQEELSMVRRCCALSNQLLTLVGNDNLASC
VASRELRVVVFSSFPVDPELYLNQLTRGVSAYFVNHAENSLLITSSGTTRAQTDVLRFLQYETGETCR
>SEQF2545_AGK83826.1 hypothetical protein TPFB_0179 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSALSSTSSPLFLSVPPPPRQEVMTQALQVPSAPARCRHLRRKNGVLLRIVEKTDRTRYAHALRHGCRHRMCEGVHGTEE
DAMGSESAEMDSPHATARPQEQGEDRAWDACGVWVKVPPEAQEPPVSSGGPEDPEAPAQHAPPGARVDAVRHHVYRALPV
QSSAEDSRGFVDLSVEDEVLARGCSHAPGGESSSDQAADAPAGDAAYSEVPSFDDLVTRTAQSQDDRVDLSAAMSSVVTE
EPPEPRGCSMPCPSGSCDTTEFDDLLSSLSHDAPEYPVDSDPITYSASEPSSEGPVRGAPFSDVDAVAQSLMGDAQVAAQ
GAQASTSGDASTDLLLKIAQEISSIRADLDQLKGTFSRQAGAEPAQAPATAPAPEGTEAAYSGFFCDDDPDETIALTNDE
LNNILITSEFTEEDGKDSAADAFGGELSGFESSHIGSAAGDFSYLEEDDHAAARVAQEQWVQQGRATLGNEVFDVKEQGA
HADRDAAADPSPVAKDDASPEAQRAHVSSTGLDAAGAEQPLNTENVFDDEDTQREDTSFPLPEEQELDVSVPSLEFSAPH
AIETAASESSEVATPVAIESPPQSEAARPAQGDSANLAPPLSKSLADEVRSVLGYMDRLLESLPEEKIEEFARSEYFHTY
KHLFDELGIS
>SEQF2545_AGK83827.1 putative septum formation initiator [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRIYLRVVLPLSLALNSYGVLAFFWGERGVCAMRLLEREKKELVHHIQTLAERGRDLAAVVDALSFDEETIGAYARQLGY
VRAGDVLVRPVNFTVAHMHTLDSGDARPLVAPACFSDTRCKVYALCVGFFVVLLQLLWGSARAYFKT
>SEQF2545_AGK83828.1 Sua5/YciO/YrdC/YwlC family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRILKHEAQSAHAAARALKAGALVALPTDTVYGFSGLVPHAVPDLICLKARGCTETEGNRREGYPFIALLADPQDVVVYT
GTRLPAEFRALWPGPYTFVLRMQDGATQAFRCPADLWLRSVIRAVGGAIFSTSANRHGEPPLQDAQDIDHIFGKHLALTV
DAGPLTGSPSAVIDLTHPVPRVLRAGAAPLPLAGLERRDSPSLPHVGEVCKE
>SEQF2545_AGK83829.1 hypothetical protein TPFB_0183 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKGVRSSRLLILFVLFAHAVHAAPRVGVYRLEVSGVPAHTETTINDALFSFIRELRGYHVVDCREQAVPHRFPEKGNLD
YIFCGAMDLTPEGIRLAVALKGKDHNATRLLSKTYETAARILLDSRHLVRDVFDRSVPLTGNQTETSSMRHTRAGEESVS
SLDALAGSWHSTEEGERIVIVSEGRGIAVLRSGLSVPLKLKISDGVLVVSQKGAVNARQFSHFPPEIAQKLAQEARPLQW
RFPKISGNNRLSGVRTAPVVRGAGHTASVEYEEVPEEWVRN
>SEQF2545_AGK83830.1 SsrA-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRGTGTHLIAKNRKAFFNYHVEDRLECGIALEGTEVKSVRAGHLSFPDAFAEMRGGELWLKNVHIAEYVHACSFAPNPDR
MRKLLAHRDQIARLKRKVEEKGYTLVPLEFYLKAGRVKVALGICKGKKLFDKRAQIKARDNARELSRSLCERHH
>SEQF2545_AGK83831.1 putative signal peptidase I [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFARWRRYSYLARREARRNATAVCSAGVGFFLFYLFITTHVVAAYRIQADSMQPTLSAGDCVLASSLFRFARIKRGDLVL
ATPLEKEDIGLFKRAMNAVLGFASLQLYRPFGAADRMFSRPQMRRVVGLPGDTVYMRDFVLYVKPHGQQHFLTEFEVSAV
SYDVRKGVLPEHWSERLPFSGFMEEMQLDEHSYFVLCDNRIVSSDSRLWGAIDGSTQIKAKAFMRYFPFGAFGVL
>SEQF2545_AGK83832.1 coproporphyrinogen dehydrogenase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRAAHRAVPFIMSSEVGASLYVHIPFCAQRCAYCDFYSLVRSTYFRPHQPCPHFIDRLLQDVALQRECFGVQGWQTVYM
GGGTPSLLAPQDIRHFCVALRAAQRYPIQEFTLEVNPEDVTEEFLCACAEGGVNRLSLGVQSLRDEVLRAERRAASAECA
RTALRVMTANARFFSGGVRISADLIAGLRGQTARMVREDIDELLSFGLRHVSLYGLCVPHPTETQEERIAALWAHGSAYL
VRAGFNRYELSNFARTAADESAHNRAYWRMAPHAGVGPGAVGTRFVNLSLSKEGAWAIRSTVRKHLGQYLAEVCRENVYE
HEFLTEHMCVQEALLMGLRLEQGLDVVTFRARFGKGIEAYIGKTIARWQCHGRMQRTATSLRLSAQARVFLDSFLREAFA
ELART
>SEQF2545_AGK83833.1 elongation factor EF1A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKEKFARTKVHMNVGTIGHVDHGKTTLSAAITSYCAKKFGDKQLKYDEIDNAPEEKARGITINTRHLEYQSDRRHYAHI
DCPGHADYVKNMITGAAQMDGGILVVSAPDGVMPQTKEHLLLARQVGVPSIIVFLNKVDLVDDPELLELVEEEVRDALAG
YGFSRETPIVKGSAFKALQDGASPEDAACIEELLAAMDSYFEDPVRDDARPFLLSIEDVYTISGRGTVVTGRIECGVISL
NEEVEIVGIKPTKKTVVTGIEMFNKLLDQGIAGDNVGLLLRGVDKKEVERGQVLSKPGSIKPHTKFEAQIYVLSKEEGGR
HSPFFQGYRPQFYFRTTDITGTISLPEGVDMVKPGDNTKIIGELIHPIAMDKGLKLAIREGGRTIASGQVTEILL
>SEQF2545_AGK83834.1 ribosomal protein S10 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARERIRVKLCGFDVELVDQSSRAIVHAVQKAGAEVLGPIPLPTRMHKFTVLRSPHVNKKSREQFEMRTHKRLIDIIEPS
QEVMNALMGLELSAGVDVRIKQ
>SEQF2545_AGK83835.1 ribosomal protein L3 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVGLIGQKVGMTQIFDARGCVTPVTVIRVEHNVVVGLKDVERFGYSAVILGTGCMKKSRISKPYAGQFAERIPPVRVMRE
FRGFTLDVSVGQVLDVRVLESVRYLDVCALSKGKGFQGVVKRWGFSGGRSSHGSKFHREAGSTGQCTSPGRTFKNVKMPG
RMGAERVTVQNLRIERIDVGLGVVMVRGAVPGRNKATVFLRTAVKRER
>SEQF2545_AGK83836.1 ribosomal protein L4 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEKTVYSVEGVALRSVELDESVFGLSVNRGVIYYAINSELSNKRLGTACTKGRSEVHGSNTKPYKQKGTGRARRGDKKSP
LLVGGGTIFGPKPRDFHYALPKKVKRLAMKSLLSLKAQGDALTVIEDFTVESGKTRDLIQVLRHFAQKERTVFILQNDDA
LLKRAGRNIPTLSFLSYNRLRAHDLFYGRKVLVLETAVHKIADFYRSKDAAQDGTY
>SEQF2545_AGK83837.1 ribosomal protein L23 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEHTDVVIAPVLTEKSNALRQQGKYVFRVAARATKIQIKQAVTQLFGVTVRRCTVMNVFGKKRRVRHRTGRTSGWKKAIV
HVAAGQSIGVLERA
>SEQF2545_AGK83838.1 ribosomal protein L2 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MALKMYRPMTAGLRGRVDLCRAELTARTPEKSLTRGKPAKAGRGAGGRISVRHRGGGHKRRYRDIDFKRDLHDIPGTVKT
IEYDPNRSVNIALVFYANGQKRYILAPKGLKVGQQVVSGEKVPLEPANALPLGVIPVGFTVHNVELTIGKGGQIARSAGT
RAVIAAKDGGYVMLRLPSGEARLVHRRCYATIGELGNEDHMNTALGKAGRARWRGVRPTVRGMAMNPVDHPLGGGEGRGK
GRNPVTPWGQPCRGYKTRKKRRVSDRFIVSKRK
>SEQF2545_AGK83839.1 ribosomal protein S19 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRSVKKGPFVDKKLYKRVVEMNKAANQRNKKVIKSYSRCSTIIPEMVGFTISVHNGKSWIPVYITEEFVGHKLGEFSPT
RVFRGHSGSDKKVGR
>SEQF2545_AGK83840.1 ribosomal protein L22 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTERVTYRAKTKFLVASPTKVRPVANVVKCKPYVRAMALLGHLSHKGARLISKVMKSAASNAIDRDKRLDEERLFVRDIQ
IDEGPRLKRLWCRGRGRGDVQLKRMCHITVVVEESVRTKDGSKG
>SEQF2545_AGK83841.1 ribosomal protein S3 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGQKVSPIGLRLGINKVWSSRWYAGPREYAALLHEDLRIRSMIRSFPECKNADIAEVEIVRHPQRVTVVMHTARPGVVIG
AKGVNIEKIGAEVQKRLNKKVQIKVKEIKRMELNAYLVAQNVARQLTARVSFRKCLRQACAGTMKSGAQGVKIRVSGRLG
GAEMSRTEEIKEGRTPLHTLRADIDYGFAEAHTTYGSIGVKVWLYSGMMYGNECRKDVGSLLRRSRRESGQKSDELVRDE
RTHAERG
>SEQF2545_AGK83842.1 ribosomal protein L16 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MALSPKRVKYRKVQRGRVKGDATRCNAVDFGAYALVCLEPFWLTSRQIEAARVALNRRIKRGGKLWIRVFPDKPYSKKPA
ETRMGKGKGSPEYWVAVVKPGTVLFELMGVERALAEQAMLLAGSKLPIKTRFAERVQEI
>SEQF2545_AGK83843.1 putative ribosomal protein L29 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRGGCAQLSYSELLSRRRELERKYLDLRFQLVVEHVDNKLMKRILRRQIAVVNTFLRHKELTELEKRGVRE
>SEQF2545_AGK83844.1 ribosomal protein S17 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRPERRTLVGLVTSDKMHKTVTVRITTRKLHALYKKYVSRSKKYQAHDEENTARAGDVVRIAESRPLSRRKRWRLVEIV
ERAK
>SEQF2545_AGK83845.1 ribosomal protein L14 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIQVQSRLNVADNSGARLVQCIKVVGGSRRRYASVGDIIVVAVKDALPTSVIKKGSVEKAVIVRVSKEYRRVDGTYIRFD
DNACVVIDANGNPKGKRIFGPVARELRDMDFTKIVSLAPEVL
>SEQF2545_AGK83846.1 ribosomal protein L24 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGKTVKIRKDDMVLVIAGKDRGKRGAVLRVLRDVDRVLVQGLNMRKETIRRKSAQDEGGIMEVEAPIHISNVMIMGKKGP
TRVGYRMENGKKVRVCRKTGEVL
>SEQF2545_AGK83847.1 ribosomal protein L5 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTDHSCIPELKVRYVQQIVPDMMRDFGYSTVMQVPKLLKIVLSMGLGEALANRKLLDASVADLGVISGQHAVKTRARKSI
ANFKLREGNEIGVMVTLRRSRMYEFLHRLINVALPRVKDFRGVSPRGFDGHGNYSMGITEQIIFPEIDFDKIERISGLNV
NVVTSAQTDQEARTLLTKLGMPFRK
>SEQF2545_AGK83848.1 ribosomal protein S14 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MATVAMINKAKATPKYATRRYNRCGVCGRPRGYMRRFQLCRLCFRKLASEGQIPGVTKSSW
>SEQF2545_AGK83849.1 ribosomal protein S8 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGVSDPVADMLTKIRNAARAGHEKVDVPSSKLKVEVVKILKTEGYIRNFRKVEEDGSGCIRVFLKYDDNETSVIHGIERI
STPGRRVYSGYKTLRRVYNGYGTLIVSTSLGVTTGRHAREQRVGGELICKVW
>SEQF2545_AGK83850.1 putative ribosomal protein L6 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRIGKVPVSVPGGVHVRVSSGVVEVEGPKGVLSCAFLPVVTVRVEQEYVIVARCDDSKRARACHGLYRKLLSNMVVGVS
EGFSKTLVITGIGYRAEVQGRVLVMALGYSNDFTVLIPSGIEVRVESSTRVIVSGVSKERVGEFAAQLRRLRLPEAYKGK
GIRYDYETIVRKVGKSGVK
>SEQF2545_AGK83851.1 ribosomal protein L18 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLRKCSDKQRKRMKRKVHIRKRVYGTAVRPRMTVFRSNRNISVQVIDDDARSTLASVSTLEKDFVLLRANVSSGLQIGEE
IGRRLLEKHIDTVIFDRNGYLYHGVVAAVADGARKAGVKF
>SEQF2545_AGK83852.1 ribosomal protein S5 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDRHRDFGKDRLRDKEFTEKLIKLNRTAKVVKGGRRFSFSALTVVGDQKGRVGFGFGKAGDVSEAIRKSVERAKRSMVLF
PLKDGTIPHEVQAKFKGSLVLLRPACSGTGIIAGGTVRAIMEVAGATDVLSKSLGSNSAINVVRATFGAVAQLMDARKLA
RERGKALVDMWG
>SEQF2545_AGK83853.1 ribosomal protein L30 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTKRVRITLVRSTIGQREPVRRTVRSLGLRKLHSMVEKDGSPAVLGMVRAVSHLVRVEELG
>SEQF2545_AGK83854.1 ribosomal protein L15 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MADFHLIAPKGANRARRIVGRGSSSGRGTTSGRGTKGQQARAGHKAYVGFEGGQMPLYRRVPRRGFSNCAFKKEYAVVNV
GALEFVYAPGETVNRQTLIEKGLVKGRVPFIKILADGELTKSIVVRVDRVSARAQEKIQQAGGSVECIEAQER
>SEQF2545_AGK83855.1 Sec family Type I general secretory pathway protein SecY [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKQGVFAAVFRIRELRARIFFTLSVLTVFRFGSVLTVPSVDPRALSAYFRSQVRGNAFADYMDFFVGGAFSNFSVFMLGV
MPYISTQILMQLSMIVFPSLKKVVEDVGGRRRVQFWTRVATVFVCLIQSSAVTVYANQIPGAIVIQSYAVHLFVTMLTVT
SGSMITLWLGEQITARGIGNGVSMIIFSGIVARLPHALAEMWRLQRLGELNMVFVIVAFVMFVGIIVLVVYEQQGQRKIP
IHYARRVVGRKMYGGQSTYIPFKINPSGVIPIIFASSFLTFPLQIASSIGPNVRFLHQLAQFLRPNSWWYNAFYVVLIVF
FAYFYTQVTLNPTEIAKQIRENGGTIPGIRADKTEEYLQGILNRLVLPGSLYLAMIAVLPTLIQAAFGFPSSISLLMGGT
SLLILVGVDLDTMSQIEAQLKMRQREGLGGRGKVLPRSL
>SEQF2545_AGK83856.1 ribosomal protein L36 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKIRTSVKVICDKCKLIKRFGIIRVICVNPKHKQRQG
>SEQF2545_AGK83857.1 ribosomal protein S13 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARIAGVDLPNKHVSVALTYIYGISRSSARTICEKARISSACLINDLSQDELAVVRAIIDREYKVEGRLRTEVALNIKRL
MDIGCYRGLRHRKGLPVRGQRTRTNARTRKGKRKTVAGKKK
>SEQF2545_AGK83858.1 ribosomal protein S11 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVTKKRKEKKNVYEGNVYIQATFNNTIITVTDLQGNALSWASSGGLGFNGAKKSTPFAAQTVAEAAVQKAQQCGLREVH
VFVKGPGIGRESAIRMLGTMGLRVRSIRDITPIPHNGCRPRKTRRI
>SEQF2545_AGK83859.1 DNA-directed RNA polymerase subunit alpha [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPRRNLLKGFKRPKVLEFLSENSSECYGKFTASPFETGFGTTVGNCLRRVLLSSIQGYAVTGVRITSFDADGVAHFISSE
FEQIPHVREDTLEILNNFKRLRFLLPQGAESSTFTYEFRGAVSLTGKDFAKKFQLEVLSQDLLIMEMMDGAHVEVELHVE
FGRGYVPAESHDRYADLVGVIPVDAIFSPVLRVRYDIQSCRVGQRGDYDQLSLEVWTDGTVRPEDAIAEAAKIIKEHFTV
FVNFDETALDLEDEPEEDDPAVLELLNTKIADLDFSVRARNCLLTMGIKTLGELTRISEQTLANTRNVGKKSLSEIQGKL
QEYNLRLGMADYNHVGVVSRLMRQKEEIDEA
>SEQF2545_AGK83860.1 ribosomal protein L17 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRHRTGFNPLSCMAAHRRALRRNMVTSLFKFERITTTKPKAAEVRRAAERLITRSKSDSVHNRRQVARFIWDKAVLHKLF
ADIGPRMREREGGYTRILKLGLRQGDAAHVVVLELVDYTFEKSLKKRARTDSVPARKGAGKKDASRVSGTVPDGQSQKIG
KKKE
>SEQF2545_AGK83861.1 hypothetical protein TPFB_0214 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSKAHRGKGIRGMVGRGRGVCPVTGQTGVKLLYECEIDGKKVKVSKVGRATLQNRKRRLDAQPGA
>SEQF2545_AGK83862.1 chaperone GrpE [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCGGDVQGQGVASGCDEALERADSLRASDPVPVESGEGSVPGEHSQELETGASEETLRERVNVLQEQYLRKAADLENYRK
RALRERQEAVEHAYAALLADIVAVLDDFDRAIEAADHASSTEVEASSAFREGVLMIRKQLSSVLETKYGLEYYPVLGERF
DPNLHEALSMSPSASVHEKIVGAELQKGYRVRNRILRHAKVMVLTPEEQTEPDRGDGPSE
>SEQF2545_AGK83863.1 chaperone DnaK [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGKIIGIDLGTTNSCVAIMEGGEPVVIQNAEGGRTTPSIIGFTSDGGRVVGQPAKNQMVTNPEHTIYSIKRFIGSRFNEL
TGEAKKVPYKIVPQGDDVRVEVEGKLYSTQEISAFILQKMKKTAEDYLGEAVTEAVITVPAYFNDAQRQATKDAGKIAGL
DVKRIINEPTAASLAFGFNKDSKREKIIAVYDLGGGTFDISILELGDGVFEVKSTNGDTHLGGDDFDARIVQWLEQGFKS
DTGIDLGNDRMALQRLREAAEKAKIALSSSASTEINLPFITADANGPKHLQRTLSRSEFEKMTDDLFERTKEPCRKALKD
AGISADRIDEILLVGGSTRMPKVAHVIKDVFGKEGSKGVNPDEAVAIGAAIQGGILGGDVKDVLLLDVTPLSLGIETMGG
VFTPLISRNTTIPTRKSQVFSTAADGQTAVSIHVLQGERGMANQNRTLGNFDLVGIPPAPRGVPQIEVTFDIDANGIVHV
SAKDLGTGKEQHIRIESSSGLSESEIDRMVKEAEANAESDKREREKIEARNVADSLIYQTEKTLKEAGDGVNAADRARID
EAIAELKTVLSGDDVASIKAKTEILQQASYKIAEEMYKRQAAAGAAAGKKSDAPSGNEAEGGDVDYEVVKDEDSK
>SEQF2545_AGK83864.1 chaperone DnaJ [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKKDYYEVLGISKTASGEEIKKAYRRLAIQFHPDRNQGNKEAEERFKEATEAYEVLIDAQKRAAYDRYGFDGLKDMHGA
HGFNSSAFQGFEDIFGGGFSDIFENIFGTSSRRGGSGNDGSGGSGRGANLRYDLQISFEEAVYGKKSELHYVRDETCITC
KGAGSASGGRKMCPDCKGTGQIRRSTGFFSIAQSCARCGGEGTIIESPCARCAGSGIERKKQKIIVSIPAGVEEGRRITI
PRQGNAGRAGGAYGDLYVFVFVRAHEYFEREGADLYCATSISVTQAILGAQVTVRALDGSAQQVRVPAGTQGGALLRVKG
MGVPLARGAGDLYVKVLVRIPTTLSARSRALLAEISQEEGENAHPPLLELSSLK
>SEQF2545_AGK83865.1 hypothetical protein TPFB_0217a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNFQVSSRLQKGARGVKGLFSRAWCFFLVCRRMSWLHRDGCVCYLSFLPTV
>SEQF2545_AGK83866.1 putative sigma factor regulatory protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRRRLAIVKAGSFALLALFFSIFLRFLSPRYSFLGRFVSARDMALLISRYEHLPELSSRDRALLVGFVFMIFALALTEI
QRYAHGRIRLVVYRQTETRLFEHFITLLRFCYRNEQLVAAFQEVLEYRADCAVLLMDTISNRVIYNSAARFVSDTRTYDL
VLHKFSMDYTWHWSDGIYFFDDDLCLMSDRRRARGVCLSSGELRLFIVCRFIRAVEREVISLLFKEFEEYLNRKRNMSTL
LLYSHVSQEWAMMARVQRALLPKALPHTKEICVGAFYQPLVNVSGDYYDVISIDEHLFLFVIGDVSGKGLAASLVMGVVL
STIRIVEDKKNLPEILYAVDRAVKRMHLHDKYTTLFLGLIDTAGMNIRYINASMESPLVFTQAGEAHEVYHLHSNCPVIG
IVDLPPIQIHERTLCPGDVMVMVSDGVVEVVNAQGVELRDADEYLHILERHVGEHPAQMAQSIAALALNFSADRTTHDDM
TIVTVQVKR
>SEQF2545_AGK83867.1 putative sigma factor regulatory protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGLLFFSYLFVAVFVFDVFCLKFYTRRAYALLANIALVSGVASFFLSLSLTAVLYGKMNIQAFLFKIALIFFTHASYLFS
DMAYQLPYFKKNKRFFLCNTTIHLFGILIIIFGMGPFKWNVLVSFKFYQNYLFSSVSGIVLYAALFFLIIPCVTFATLVK
KAFMMKSIAYRQQLLFLAGAVALGFITWVIILFLFAVFPWVFVFFPLGGVFIVLFSQWAFASTGIVSFKEVVFALSRFVL
CTVGFSCTAGYISVFWVHRFSTLDMQFVFGFFIVYALFALRDYAFDACSVFFGEIADSGQKLAAELQALDYTAKPAQVLR
TFMDTLRMRIACRGLTFLLADEAGVFKTVYSDFEEMATHEMEHQSLQYFFNQDVLMIRKSDPVIDHARQAIRTDILHFFD
ITHAQMIVLIREAQKLIGCLCFGMKNNGVEYSNHDQHVLEKLYSHFVLVSYYLQNIAKQDVVITVDKELKMSHQIIESIQ
RKRDFIQDASVEVDSIAYSAHQLGGDFVDFIKLSEKRYLLVIGDVSGKGLAASMSMVILKSVLSTFLRGLCLEETAVFTT
FIEKINRFIKDNLPCGTFFAGVFCILDLATHTLYYANCGIPLMSMYVASYKNVVEIQGEGRVLGFVKDVMPFLRVRKVQL
GQGDVVVFSTDGMVEVQNLQRERFGNERVDRILQESHGLPVSQITRTIYARLCEFMARDMQDDVTVLAIKCLGPR
>SEQF2545_AGK83868.1 anti sigma factor antagonist [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDNINIAKDVRPGCVLLTVTGAVSSYTYGEFESRVHGALKENHVVLDLSGVTAMSSSGLGVLISAYDEGLKYQRRLCILN
PSESVRRAIELTGFSEMFTVIKSLDELD
>SEQF2545_AGK83869.1 serine-type D-Ala-D-Ala carboxypeptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSWTKWRVGTACAYAGYVLVALGNAVSPQGVDRVDLHRVRAAAKRAALPARLATRLCAQGREFLQELDAVLTTEGYLLRL
VDKKHPLPETFVPKHLVPVREQWLFFSKGRSLLLTKIAYEALHQLIQAAAHDGVALSVGSAYRSFAYQKKLFSWYAQEHG
MQEAMRFSAREGTSQHQLGTVVDFGSITPAFARSDAGRWTQRNAHRFGWSLSFPPGYEQVTGYVWEPWHFRYVGVRACAL
QKKWFEDIQQYMLGFIHEWKVNASS
>SEQF2545_AGK83870.1 hypothetical protein TPFB_0222 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MWKRGVGALLWGMVLLRSFVAYADSQAATGGLLKEIMGEVASIRLESNMLKQQLRERHAESAALKKALQTLDVKLEKAAK
ALEESEHALSESKELIETLRSELEILRQRVNALNMRLRRLEITNNVLIGVAVVCGVAAIGAGIYAAVK
>SEQF2545_AGK83871.1 pyridoxal phosphate-dependent aspartate aminotransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDLSEGARALNAALEGTVVHALLSPLGLRAYFPHGIVAQNAEARMRAPDMNGAVGMVLRHGVPVLRDTLHALVPDLSSSE
IVSYAPTAGIPALRERWARRLCARDPVLCPDEPDVAAMQSAAEQGEHSCAAVFPKMSLPIVLPGLTAALSCAMDLFVGAG
QTVLVPAPRWENYDLMLAVRCAATPVPFSLFRAGRFDLSACKEALDAQASDGVIRLILNFPHNPSGYTPTEEEAQQLYEV
VYAYADAGCAVLVICDDAYSGFEYEASLMRGSFFARFAQAHKNICALKIDGLTKEEYAWGLRVGFLSCAGLALGVSQYQA
FEKKVMGMIRASLSCTATLTQTLALRLLAEEDEPAGLGSATARERHQFFQLMCARYREVQRVVRDLTWSTTECGAAVPLR
VEFLPCNSGYFTCIRCIGFSAETLRQYLLEQCGIGTVAIDEQHLRVAFSALELPAIERVLRAVVHTAVQLSCVGEGSRS
>SEQF2545_AGK83872.1 hypothetical protein TPFB_0225 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPKQVVVFAMWCIGLGVLVSHPVSAKQNAVSRAEVKETPAKFFQYGLTPDRDGIIITRYLGKGIAVVLPSQIDGLPVVEV
ATKAFYGCVSLVRVSLPSSVRMIGQHAFDGCTKLARIELPDGLREIRHHAFHKCVSLAGIVFPRSLQVIGQDVFSSCESL
VDVVLPNSVKEIGSGAFRDCAELASVRLPVGVKNLADGLFEGCRNLVELGNLPEKVSFGVGVFVGCYRLPDVLKRSVRKL
GYKGEF
>SEQF2545_AGK83873.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFFSLYERRQSLLHRAPPVAKVASFALLLLCCNAQSWCMHASLTLVLLALTLIVTRSLKCVAAHIRVVSIYLAFFFSLKI
LHTFFSTGVVSATQINQHIHAGYHIGIRLFLLLCASSLFYACTSRLELFSLCLRMGKVLHVRSTAYTTPCAVYVMMLVLY
FGHDIFREWTELRLVWRARTRANTSFYNWVDATLHFSKTLLTRLLERAQHPSLRRADFKVSDNILSSE
>SEQF2545_AGK83874.1 hypothetical protein TPFB_0226a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHYSTGEGERSLRLSLREEHGEAAIAGVHKERKTYISLTPPSRWKYCMHVAT
>SEQF2545_AGK83875.1 putative cobalt (Co2+) ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSADVAADTAVESCAGPLLELVNVSKSFERDCEVLHSVSFRVFPGDCVVLAGANGSGKTVLMNILAGLEPPSSGRVYMAR
GTTVGLAFQNADTQILGETVFEDCAFGPLQWGYSRAEIDARTNSALAAVSLLDRRDHYARALSGGEKRRLTVAGVLALDA
KVVILDEPFANLDYPSVRQVVQLIISLKHAGKTLVIIAHEVEKILAAATRLCILSKGVISYDGTPQDALDSKIFSCYGLR
DPLHCPRTLSDLLWT
>SEQF2545_AGK83876.1 BioY protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHRSKSLAFVALFAALISSSALVSIPLKPVPLVLQNAAAVLTGLLLGPRDGALAVLSFLGAGLLGLPVFSGGRGGYTALF
APTGGFLLGYILAATLAGAIAQHHRLSCTPPRGGGRALLLWIRLTVATLVGFLSIYSIGLPVLGYVLGLRTGELMLGVFL
PFFLADTLKIALVVLLAHHLAPTVRRHLYRHG
>SEQF2545_AGK83877.1 uracil DNA glycosylase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYAVYGRLSPMHAGDRESIARFVRVVRDCLDLFRTEGIGPRPRNDSVILPNAACSPRNHAGKRAQSTADACVRSSDGSVY
TDETLREEIFACRACELYQRRTHAVVGEGVADADVLVVGEAPGAEEDRSGRPFVGRSGKLLDAMLAAIGLSRQQNCYITN
VVKCRPPRNRTPTPHETACCARFLHAHLTLHRPCAILVLGRCAAQHMLQTTDGIGKLRGRFFTYQGIPLLATYHPSALLR
DEALKRPAWEDLKTFRARLLQLKQDAHMPI
>SEQF2545_AGK83878.1 DNA replication factor Y [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAPWLELVFDVPLDKSFTYRACAAHAGEALVGRRVLAPFGARTLIGFVISESHSSPADCGGAVGTFKEIIRVIDREALFD
QTHLACARWMAHFYLCALGQALCAVVPSRKRERTLSSFASCAGVRRTDTYALSGEQRKAIDAITASTGARSFYVHGVTGS
GKTEVFLRAAEAVLARGKSVIYLVPEIALTHQVLQEVYVRFGSQAAVLHSALSGSQRLGEWRRIQRMRHCVVIGARSAIF
APLKRLGLVIMDEEHDSSYKSAHVPRYHARQVAMYRCADANCPFVMGSATPSVEAWYAMLRGAVRRLPLTARVAGGAPPR
VEVVDVSKEALLLSTRLVDEIRKTKEAGYQSMLFLNRRGFSYSFQCRSCGYTLCCTQCAVPLTWHKRVGAMQCHYCGRQE
APPESCPCCHSFDTRYGGVGTEYIEEAVQALFPEYRIARVDTDALRSGHVQQTMEQFRAGKIDVLLGTQMIAKGFNFPTL
RLVGIACADTGLHTPDFRAAERSFALMMQVAGRAGRYVDNGLVIIQTRNPAHPAVVCAQHGDCESFYAQELAQREALCFP
PFVRLIRFVFRSKTRRKAKDAAYAAHALLTAQMPLGADVLGPAACVVAQVAGSYRMQILLRAPSFPVVQQVARSFLDEFR
APAGVYVESDVDPVNVL
>SEQF2545_AGK83879.1 pseudouridylate synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MALPIIFQDAAVVAVDKPAGLAVQPGARVRVCVVDVLQKQLGVRLFPLHRLDKDTAGVLLFAKHARAAALYQGILGSMRV
IKRYRALCFGRPPRECGDIRVPIRTGTAARRRQVVRAAHTAYRVLRATDTHTYLELTLHSGRTHQIRIHLAALGCPIIGD
DKYGDFARNKACARAWGVKRLQLFAHSLVLPCACKPLVLRARMPVHFLRALDAVAL
>SEQF2545_AGK83880.1 anti sigma factor antagonist [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGTVVPGFDDEKDESLKMNLQKIDDLEGGVVVFLNGYIDTYNSSFFQKRIAKVIDAGYTRIVFNCASLNYVSSTGIGSFT
AFLKTVKPKGGDIVLLDIQPKVYEVFQLLGFSQFFNIRDSIADAVSLFRNKVSPLKVDTFPKVFSCPICSKKLKATKQGR
FRCSECKTILALDASAHVSLG
>SEQF2545_AGK83881.1 ribosomal protein L33 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKRTAVELIALQCTGCKRRNYTTSRNRRNVQEKLELRKYCPFERRRVLHREAKIK
>SEQF2545_AGK83882.1 Sec family Type I general secretory pathway protein, subunit SecE [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLKFAKFRRECVAEFRRVVWPARTQVHTAVKVVLVSTVVMALFLGLIDALFVALLSFFF
>SEQF2545_AGK83883.1 transcription antitermination protein NusG [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKEWYILHTFSGREARVERAVRMLVEHARIPTNVIFDIKIPEELLTEVKDGKKRVVRRKFFPGYLLVEMDLPEVDWRIV
CNEVRRIPGVSGFLGSSGNAKPQAVSADEARRILQKAGEIKGDRTPRIAQTFLVGQQVRIVEGPFATFSGEVEEVMSERN
KVRVAVTIFGRATPVELELVQVEAL
>SEQF2545_AGK83884.1 ribosomal protein L11 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAAKKKVVTQIKLQCPAGKATPAPPVGPALGPHGVSAPQFVQQFNDRTKSMEPGLVVPVVVTVYSDKSFSFVLKTPPAAV
LIRKACGIEKGSTNSVKQKVARLSLAQLTEIAQVKLPDMSALTLDAAKRIIAGTARSMGVEVERSL
>SEQF2545_AGK83885.1 ribosomal protein L1 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRGKKYRAAVARYDRAERFSLDRAVGLLKEVRYASFDETVEVHVSLRLKKNQTVRDTVVLPHRFRAEVRVLVFCKEDRV
SEALAAGAAYAGGAEYLEKVKGGWFDFDVVVASPDMMKDVGRLGMVLGRRGLMPNPRTGTVSADLGAAVCELKKGRVEFR
ADKTGVVHLAVGKTTMDSAQIVENVDVFLSEMDRKKPVDVKAGFVRSISLSSSMGPGIWVVHKSEE
>SEQF2545_AGK83886.1 ribosomal protein L10 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVRARRLQPAKVAAVESLTRDLGEASSYIFTEYRGLTVEQLTALRRALREFSCVYRVVRNNFANIAFTSLNMTVGEYLV
GPTAIALVDTEHANGVARVLFDFAKEVPALVVKGAILDGEVFDASKVEAYSKLPGKKELVSMFLSALNATTVKFVRVLQA
VMDKRDEGVEVSVVSGGDSS
>SEQF2545_AGK83887.1 ribosomal protein L7/L12 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAALSNEQIIEAIRGKTILELSELIKAVEEEFGVTAAVPVAPVAEGGGAGSVAAEEQTEFTVVLKGLAEPGKKIAVIKEV
RNVISGLGLKEAKDLVEGAPKTLKENVSKEEAAKIKESMTAAGALIEIS
>SEQF2545_AGK83888.1 hypothetical protein TPFB_0240a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MWEGVALLSRAWASISFHTCSRHFGMRVGSRSPHLSGGDGVSPVWGVLR
>SEQF2545_AGK83889.1 DNA-directed RNA polymerase subunit beta [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSARVCKTHRVYVGKDVRNFMDIPDLIEIQLRSYDTFLHGARNTPSGADTLISGTREELGLEDVFKTTFPIESSTGDMTL
EYQSYSLDEKNIKFSEAECKQKGLTYAIPLKALVDLRFNNTGEIRRKDIYMGDIPKMTERGTFIINGAERVVVSQIHRSP
GVVFSHEKDKEGREVFSSRIIPYRGSWLEFEIDQKKDLIYAKLDKKRRILGTVFLRALHYETREQIIEAFYAIEKTPVCQ
DRVEYELLTGKILARSVTVENEQGETRVLYKAGEKIHPHVIDDLLQNGICEVYIINLEAEGSLRSAVVINCLEREEMKFS
KSGAQDELSREEALCIVYSALRPSDPMTMDAAEKDLQTMFFSPRRYDLGRVGRYKLNKKFRSDSPTTECTLTLDDIVNTM
KFLIRMYSGDAQEDDIDHLGNRRIRSVGELMTNTLKTAFLRMERIAKERMSSKETETIKPQDLISIKPIMAAIKEFFGAS
QLSQFMDQVNPLAELTHKRRLNALGPGGLSRERAGFEVRDVHYTHYGRMCPIETPEGPNIGLIVSMANYARVNGYGFLEV
PYVRVRDGVVTKEIEYLDAMDEDRYYIGQDSTAVGPDGVIRVDHVSCRHRGDYSTRSPKDIQYMDVSPKQIISVSASLIP
FLEHDDANRALMGSNMQRQGVPLIFPEPPRVGTGMEEKCAYDSGVLVKAKQDGTVAYVSSEKIVVCSAAASGEEQEVVYP
LLKYQRTNQDTCYHQRPIVHVGDRVQVGDALADGPATYRGELALGRNILVGFVPWNGYNYEDAILISHRVVKEDMFTSVH
IKEFSTEVRETKLGSERMTNDIPNKSEKNLDNLDAEGIIRIGSKVRAGDVLIGKITPKSESETTPEFRLLNSIFGEKAKE
VRDSSLRVPHGVEGTVIDVQRLRRSEGDDLNPGVSEVVKVLIATKRKLREGDKMAGRHGNKGIVARILPEEDMPYLDDGT
PLDVCLNPLGVPSRMNIGQILESELGLAGLRLDEWYESPVFQSPSNEQIGEKLMQAGFPTNSKVMLRDGRTGDYFQNPVF
VGVIYFMKLAHLVDDKMHARSTGPYSLVTQQPLGGKAQFGGQRLGEMEVWALEAYGAANTLQELLTIKSDDMHGRSKIYE
AIVKGEASSPTGIPESFNVLVQELRGLALDFTIYDAKGKQIPLTERDEEMTNKIGSKF
>SEQF2545_AGK83890.1 DNA-directed RNA polymerase subunit beta prime [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKDIRDFDSLQIKLASPDTIRAWSYGEVKKPETINYRTLRPEREGLFCERIFGTTKEWECFCGKFKSIRYRGVICDRCGV
EVTHFKVRRERMGHIELATPVSHIWYYRCVPSRMGLLLDLQVIALRSVLYYEKYIVIEPGDTDLKKNQLLTETEYNDAQE
RYGGGFTAGMGAEAIRTLLQNLDLDALVAQLREKMMEKGAKSDKRLLRRIEIVENFRVSGNKPEWMILSVIPVIPPDLRP
MVQLDGGRFATSDLNDLYRRVIHRNSRLIRLMELKAPDIIIRNEKRMLQEAVDALFDNSKRKPAIKGASNRPLKSISDML
KGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLWQCGLPTKMALELFKPFIMKKLVEKEIVSNIKKAKMLVEQESPKVFSV
LDEVVKEHPVMLNRAPTLHRLGIQAFEPVLVEGKAIRLHPLVCKPFNADFDGDQMAVHVPLTQAAQMECWTLMLSNRNLL
DPANGRTIVYPSQDMVLGLYYLTKERSLPEGARPRRFSSVEEVMMAAEKGVIGWQDQIQVRYHKCDGQLVVTTAGRLVLN
EEVPAEIPFVNETLDDKRIRKLIERVFKRQDSWLAVQMLDALKTIGYTYATFFGATLSMDDIIVPEQKVQMLEKANKEVL
AIASQYRGGHITQEERYNRVVEVWSKTSEELTSLMMETLERDKDGFNTIYMMATSGARGSRNQIRQLAGMRGLMAKPSGD
IIELPIRSNFKEGLNVIEFFISTNGARKGLADTALKTADAGYLTRRLVDIAQDVVVNEEDCGTINGIEYRAVKSGDEIIE
SLAERIVGKYTLERVEHPITHELLLDVNEYIDDERAEKVEEAGVESVKLRTVLTCESKRGVCVCCYGRNLARNKIVEIGE
AVGIVAAQSIGQPGTQLTMRTFHVGGTASSTTEENRITFKYPILVKSIEGVHVKMEDGSQLFTRRGTLFFHKTLAEYQLQ
EGDSVQVRDRARVLKDEVLYHTTDGQTVYASVSGFARIIDRTVYLVGPEQKTEIRNGSNVVIKADEYVPPGKTVATFDPF
TEPILAEQDGFVRYEDIILGSTLIEEVNTETGMVERRITTLKTGIQLQPRVFISDESGNALGSYYLPEEARLMVEEGAQV
KAGTVIVKLAKAIQKTSDITGGLPRVSELFEARRPKNAAVLAQISGVVSFKGLFKGKRIVVVRDHYGKEYKHLVSMSRQL
LVRDGDTVEAGERLCDGCFDPHDILAILGENALQNYLMNEIRDVYRVQGVSINDQHIGLVVRQMLRKTEVVSVGDTRFIY
GQQVDKYRFHEENRQVEAEGGQPAVARPMFQGITKAALNIDSFISAASFQETNKVLTNAAIAGSVDDLCGLKENVIIGHL
IPAGTGMRRYRQVKLFDKNKRDLDVQMEEVIRRRKLEEEALAQAVAGMEGEPEGEA
>SEQF2545_AGK83891.1 ribosomal protein S12 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPTINQLTRIGRKAVFSRTKSPALQACPQKRGVCTRVMTVTPKKPNSALRKVARVRLSSGVEVTAYIPGIGHNLQEHSIV
LIRGGRVKDLPGVRYHIIRGAKDTLGVVDRKRGRSKYGAKRPRA
>SEQF2545_AGK83892.1 ribosomal protein S7 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRKRRVSRRVPPPDARYNSVVLAKFICRMMLAGKKATAVGIMYDCLERIQQRTGEEPLPVFTKALENVKPAVEVKSRRV
GGSTYQVPMEIRETRREALGMRWIIGAARRRSGRGMSERLAAEILDAYHSTGTAFKRKEDTHRMAEANKAFSHYRW
>SEQF2545_AGK83893.1 hypothetical protein TPFB_0245 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLQGRCLPLAGGVFALVLSLDSSGRRFWVACSCAPYQHKRRVHTVGGLLSDPHNFARACALFREFSAREERSGVVRAELK
CPVDVRDSFLRASREIDPRAAHSLQQEEVLGDGRAALCSADCLLLQAFTHFHNTELARYRARLADIDARIVYERFLRDWE
CAVACAHFGIHRRSTVFTRVHSDAIRDLEEQRAALALETPESFFVLHAAQWLGEVERVSSGVFAQTPSVSAALERIATSL
ARGDAVLLRGHLGTGKTELAVLAAERFALHKLITEDVRCALNEWCTAATGGSCAEIRGSERGVSDALQNSQEARTQFQRL
FSQRAAYYEQALRLGDERLLQRIKPLFISGSKHIDTEDLFLEKTLVLKNSLEGKTPEHCYQDVHAFTERGYAFDPMLDIY
LAKYGNFGTEVQKIEREVLRAVKEGRPLVIDEINAIPMQHLIALNDILQKRVGDFAYIPGVGPVKIAAGFGVIATGNISS
GLVHYEGTGALNPAFASRFNTFEYDYPPQSTEGLYTNQAHPEKNELFRIILARLASSGGSLCLPDIDGSLDKLFKLAQLA
KVTQQVFSGKWKDSTGGSETHDGLGDVEPELREAVLSIRNVIRVLDEWNRGEEKDVDQALWDGFIGGVLNADDQNYILSQ
AVRFGFFQEKDGWSVRPKGIGAGFTSYEEIRTRPYEYTRLPDGVKTLAEVVVLLFGHGPTYAMHTQNTVPDVVDAGAMLV
LHDRIHELVRVCAAFRLLQEKSYARECADRIAHLQCSCDQLVSEHARLRSEGGTPRALWDDLARAEQTSDALIQELLPEF
RHCFPDICGDECTYSDVFFEFGKSITAAIPLAEDSVLIAGGTDDIRLLYRVHDQWLVAESTHKSVKTDWRICALISMGDG
EVVVVTEGGETIVLSIQERSKKAERRRVSFEVVARVEGVYERVLCVEKVNAHRVVVGDETGALFILEKSAHGYEYRGPIL
GLGGGIRVVRALNTAQLVVFSGFSGTRLLHNEEYSDAIYGFENPYTEAVVLSEDRVVVFGDDGECRVLRHEHGMAAGDYA
YGEWITGFKSVVLCALALSSRMVLVFGRGGEARLLSFDATGTAQYSRSFGNTTGAVVSAFLLQSEHPSVFNVFIAAENGT
CRLLTVHEFCEPSMFKERLSKIVAPPLHDNE
>SEQF2545_AGK83894.1 von Willebrand factor type A domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTMNECDAKRAQENFARFFSAEARNIATFAGDAHFRCVPILQADRFVFVPQEGMVGVPLQWFLKDDFDGKEILWNLFREL
VYYRELKADYAYYCNRVSFFEDAAQGMRRLMYEAVFSREARDEIRVRAFVQHYCHTEVASLFYLFDAVYAFHYVRNRAPY
YTTPEGSALLASLYQKERGVYWEHTETALHLQFAYALAERVLFHDMPKGCNRACIARDPVVQEVLRTLVLGTEMSNFIHS
EFFPLSGEVVPTKHRDRIVSVFLLEHFVRLWHLSVANITFELKNITDRSYDPFRNERAFEYTKSNLHAVHSRDGQQELKK
REDVFESCTTQFDERFSISPKERKEFARLLRTTHRLRIDMRSFWKSLIGKSVQWIDCYEGKCPKGRLNVGDFVSVFPDFQ
EFRGRDQRYKLRVYDRVYEVRACTLRPAQIEVSFVVDNSGSMNKEKIASAREALAVSMLSLKDFGEYSDMLAAGRRERTT
IHSEVYYFGSSFIKVKSFGKSKSKDFNSAQLIKASVNLDGRFGGTNDAEVLKHILADVERRRARVSSDTSFVKVVLVITD
GCSSYPHESRRTIEELRRRGVMIFGFQIGLMSPEETALFHDVWNSTEELGLLLGERLEYLPRELLRTLRVVLSKVHRLSS
GERLHAQRVW
>SEQF2545_AGK83895.1 N-acetylmuramoyl-L-alanine amidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHWYFDRVSRARGIMKFLRSCLIGGVFFFALCLSADEAFVSAMKLARTLNVSVSWNPLSQTILFSKGERRVQCRVGQVLA
LLDGSEVLMIDPPVVKDAVVYVSGGFAERLRKVFGYSSHQPEHRVGAVLIDPGHGGKDWGTKGSYREQGKTVVVKEKDIA
LRASQNIYDLLTARYPDRKIIMTRKGDSYLTLEERVAMANGVKLGKYEAILYVSVHANFSWNTKASGFEVWYLPPEYRRS
ILDKNAASKEVLPILNSMLEEEFTMESIMIARSIADGMQASVGAQSKNRGVKEEAWFVVRNAKMPSVLVELGFVSNPVEA
RLLNDADYLKRCAQGIYNGLVSFITYFEGSGGFTGPL
>SEQF2545_AGK83896.1 hypothetical protein TPFB_0248 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIGDGAALYGVVRAVCWTLLLIIGVALAVQQLAGERCIRYVLFFERMRDGTVVCEPRYVRGHTQGGAVREVVRELLLGPQ
HHGYARLVDPAVRPLSCFSRGDTLYIDLPVGVLSPKYRTCSLHRAYELFERSVVLNCAPVKRVCFYVGGRAGFESDG
>SEQF2545_AGK83897.1 flagellar filament outer layer protein FlaA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKAVVLSAVALLSGVCAVADESVLIDFAKLNADIMADKSGGMTHNRRTVLDYASLADTSYTDEQKALMRSSLAVAQWEV
VLNSSARNPVAHAASRVIEAPVSEGAKSFAGERVLGVRVLFPTWDSNANAMIKPAFVIPAYEVMAQVDDQGNVQAPTEEE
KASGKGRFEDGYGVVKNVGVLKSIAVNTYGMNYPHGLYVMMRDQDGEVHRYFMGYLLFDSWKELVWNNPSYISDVRSREV
RLYPVYPASTPHVVFEGFMVTRDAAHAGGDYVGYFKDVKIIYDKAVLSTVRDFADEDLWGIQARREAERKRVEVARFGQQ
QVLRYIEQEKLATEVGFTPSGGAQRQEEQQ
>SEQF2545_AGK83898.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSFPSLLFLGFSGVLAFGEVGWVGVYPPGRGMIRVRCVGCVVGWLGLRRVLVRGGIWLLLHPGIGRVLCLYLGAW
>SEQF2545_AGK83899.1 bacterial DNA-binding factor [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRVRRTRSFVVDALCDEVDLSRRHVARVVDSFVSVVTAALERGETVELRDFGVFESRVRKASVGKSIKTGEVVSIPSHC
VVVFRPSKRLKSAVRGYRSGEVGAD
>SEQF2545_AGK83900.1 apolipoprotein N-acyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRIEEWCRSRLGEFLLFVLAVSLFALSHPNPLLPRGCALLAYGALAPLFLLVRWASGFAVVFWGGAYGAFSYGAFSYWLF
VFHPVALCVVAGFSALFLAALCLALKAGGAFWQRRALLVQCLVWLGYEYAKTLGFLGFPYGVMGYSQWRVLPLIQVASVF
GVWAVSALVVFPSAWLASVLGQWVEESERNARAFLSAAYSHWVSALVWVGLCGFCVCAAKAGWWPDCTAHTRAKVALVQP
NSDPRRGGIESYRADFSTLTYLSDWALERYPDVDLVVWPETAFVPRIDWHYRYRHEQQSFQLVCDLLDYVNAKNCPFIIG
SDDAYKKRTKEGNWERVDYNAALLFIPGVNVLPPSPQRYHKIKLVPFTEYFPYKRVFPWFYNFLEKQDARFWAQGSEFVV
FEARGLKFSVPICFEDAFGYITREFCARGASLLVNISNDSWAKSLSCQYQHLSMAVFRAIENRRALVRASTSGQTVAIAP
DGRILDELQPFAPGVLVADVPIVTCACGGYRYWGDALGVFFCVASLFILIAGGVRHMLRCRRGGWR
>SEQF2545_AGK83901.1 hypothetical protein TPFB_0253 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGGRVGSLFLCGVPFYIDCWWCAPYAEMQEGRVALKRVSEGHGKTVLGAKTVFDGVLRFKGNLHIRGKFSGAIDAQGCLT
IAPGAVCAVQYARAVSIFVEGEVRGNLTVVDRVEMRDGSRVFGDVTASRIKICDGVTFEGSVCMTREGNVSKRDLFSVQS
EQLKEHLRR
>SEQF2545_AGK83902.1 transcription termination factor Rho [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKVSVGTVVGQGELGLEEGIVGNQIVSEDSAADVGECDAYGGRKKLVIRSRSRRRVVTPKALEVEKRPRRALRFKQNFCP
EDAETSESSADVKGRARLLIDDLTEMGMHALRDFAVQRGISQEDVVVMKKSDIIFHVLKNHTENGGVIFASGSLEILPDG
YGFLRSPQNSYLPGSDDIYVSPSQIRLFNLKTGDTIYGQIRSPKEGERFFAMLRVETVNFEEVAKVQDRVPFDSLTPLYP
REKLNLETRTEDISTRVMNLFCPIGKGQRALIVAPPRTGKTILMQKIANAITQNHPEVYLIVLLIDERPEEVTDMERTVD
AEVISSTFDEQATRHVQIAEIVLERAKRLVEHRKDVVILLDSITRLARAYNQTMPTSGKVLSGGVDSNALHKPKRFFGAA
RNVEEGGSLTIIATALIETGSRMDEVIFEEFKGTGNMEINLDRRLSDRRLFPAVSIKKSGTRKEELLLTEEEMQRIWVLR
KVINPMDDAEIVELLIDKMRKTKNNEAFLRSMNTGAFSS
>SEQF2545_AGK83903.1 ribosomal protein L31 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKGLHPRYEETKVVCACGNVIVTASTVKDLRVEICSACHPFFTGKQKLVDSAGRIDRFNRRYKIRG
>SEQF2545_AGK83904.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRLSDFYTALRLALVLPFFALYHMSRWVVMYFPAANVGRVVSIASVLLFLFIACTDFLDGYYARKSGKYSSFGKVFDPFA
DVIANVTVMLCLVADNFMPVFLFLCILYREFGMMFLRMLACGEGHVVGAQRMGKLKTASYMGAVLFSLLLKALYAFELAG
ADWYERMRAVGRLVYVVPVVLALASFFSYLKTFFPILKRVCGRTRYPVCKTCREWD
>SEQF2545_AGK83905.1 glycerophosphodiester phosphodiesterase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRGTYCVTLWGGVFAALVAGCASERMIVAYRGAAGYVPEHTFASKVLAFAQGADYLQQDVVLSKDNQLIVAQSHILDNMT
DVAEKFPRRQRADGHFYVIDFTVEELSLLRATNSFYTRGKRHTPVYGQRFPLWKPGFRLHTFEEELQFIRGLEQTTGKKI
GIYSEIKVPWFHHQEGKDIAALTLALLKKYGYQSRSDLVYVQTYDFNELKRIKRELLPKYEMNVKLIQRVAYTDQRETQE
KDSRGKWINYNYNWMFEPGGMQKIAKYADGVGPDWRMLIENEWSKVGAVRLSPMVSAIQDAKLECHVHTVRKETLPSYAR
TMDEMFSILFKQTGANVVLTDFPDLGVKFLGKPARY
>SEQF2545_AGK83906.1 hypothetical protein TPFB_0258 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLSLGPFHRKGWHCNSLRIRTQSTETVTHVGARSFRSAVFTLLTTVCALCGDPAHAYLVQFKEQFYRLYHTHLHQYPDEV
IENIHWLERAVHADFANPLYALAPIRDKKSWEKYRALFMMHLNLKLTEQHLRLGEKFDKREALFFNAPWREENIESLATA
ERCYHTARRYWHEAALWAERANADQFRFLFLTELPAWEDERERIARGTLNYARTISRELARLEAVRARFMEMNDTY
>SEQF2545_AGK83907.1 hypothetical protein TPFB_0258a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRTVCALAKSMPYDFPHEVACILSSLGFCVKMGRYFVRIVRAVWRRRR
>SEQF2545_AGK83908.1 LysM domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYLVFIGVLCENGPLFCPDCACSLEEETMMRKLSTGLLLWIAFISGVTSCKSAPPAEELVEVAPPVEEQEEEPMTPVPEE
PQEPMAVAPQEVSRAEYVVKNEDTLSQIAKKFYGSRIRGYYFPIIMACSEGVVTHPDRIRPGMKLVIPNFDEFMADPDHV
RRGLEAFAQVERIYRSEGKMKLAEFMNKLGEKIGKTDPRDMPR
>SEQF2545_AGK83909.1 hypothetical protein TPFB_0260 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCYYRYVQVHSIWRRFCALGLLVPFLLLLFSCTNTVGYGVLQWSLPDLGLSTGDILPVCVRSNVSQVYIVEIQKKKVELP
FWQLKLCRTKKEALQYAERLREYRYSYATSVLDGLPLREGPENTAPQVYRLREGQAVKLLWKGTGKAVYRGENRLEGDWF
KVMTEDGTTGWCFSHGLSLFDERESRPTVRETDDLARDRDLQHVLNSAWYPEYYRTMVEQRRIDLEKMASGWGLFVGEKK
GLARIELPDAHYAFPYSRLVKTGSNGYLFDGSSLSIYVRDAHTLAAQFTDEAGRLRIERFVTLEKTPEEIIAEEQLRRSA
LLEHVCTPGLRLHSEIYGTLSFTERNVFTWTGARALSPALIPAGAGSTGRVALRCFIDQSLKSEYEGVLSFDFDSAQEWV
HFLYLRTPGGLKLEHIDSTHLKDATVLRRSVSPVVLYFAPEGHAEPQP
>SEQF2545_AGK83910.1 cyclic nucleotide-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGAALFLGVAWKTEADVPKAIQYKANSVIYFSGDLDDRVMILNKGHVALTFADVETGSQVTEYIKTGEFFGVKSALGNFP
REENAITLVDSIVYAFGSQEFEAFAQTNIRIVMKMLKVFSRQLRSVHRQLESLLDSQEETNNEEGLYTVARAFHASEHYL
AASQVAQRYRELYPDGKHRHDIASMLESADGTVGRGFEEAGAQGSDAGFEVPSAFAESAVDSEVGDLRAAELLEQQGKWG
EAYEHYRLGCASNGGVGAEAAYLGAGRCLFEQREFVRSIQTFTECITRNPKSTRLAEVLMYLGQCYQGMGRPDKAISFYD
KALSTAPESLVPRIKELQRSCEEASHG
>SEQF2545_AGK83911.1 cyclic nucleotide-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MADAFASFTRFAKKFQRGSVIFAEFDVGESFYLVQSGRVRLIKIINGKERYLDVLQPGEIFGEMSILDNSPRSASAVAYD
DVVALEFNRENFEVLMMGNPAIAMRLLKTFVRRIYTQKRRFMILTIQDSTARVGDVFLMLDETQPHVDRSSDARSFDISI
EEIARWAGLSDREVQDALRRLSDQRKVECQERRIVVKNMTDLNRYVTMRRGKGDGLPLG
>SEQF2545_AGK83912.1 fibronectin type III domain protein/putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MWKGRYSAAMGALFATIFALVGVWCGVWRGEGNAAGVLYAKEAQLLLGGAQGWQSLTRVKNLRTRVGRAGHPALELSSAA
RTRSVRGDLYLSFDDPLVSDLYGRYRVQSSSAQHVGEERAHRGAGAALFRTMHRSVPSAYGGAAGGDGAEGVVLQPNPGA
LFYGSQALSSFSIEFWLYPAVSENGAVLFRWRSSLSDRGRSFYQHIVAHILQHRLEWRAEGLWNDVRGQAVSLRLRSRTH
VLPERWSHHMLTYDETRGVLEYRMNGRTECLEYLTDSQDETGQVWHARLGAAAAVHIGERYSGLIDEVVITEEFVPPSEA
GEVLRRFNRLARFDQAGGRFESEITDAGGLQAVVRRVNADVDIPEQADVAFFVRVGQTKEDWTLEYPLWQPVVAGQPLSG
LEGRYFQVAVQLYPDGAGRKTPVVHAVTVDYEQDERPLPPGRLFAQAADGSVILTWTPSVDFDVEGYVVYVGDTSGMYFV
AGSPIRVGKRLSYTVRGLQNGVLYFFALAAYDGAGEERIGQLSAEAWARPLPHLGTADIPSQGG
>SEQF2545_AGK83913.1 deoxyribose-phosphate aldolase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MELNAYIDHTLLRPSASEAEVLRLCQEAQHYRFASVCVNPCHVALAAGAVRGTAVRVCSVIGFPFGTHVTEVKCAEAQRA
LDDGAQELDMVVRIDKVCAGEREVVEREIAQVAARCHARGAIVKVIVETALLDEMHIAFACSCVEAGHADFIKTSTGYAS
RGGTEGDIQCFKKYLKGETKIKASGGIRTRAQAQRFIELGCARIGTSNGVAIMEERAS
>SEQF2545_AGK83914.1 hypothetical protein TPFB_0264a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHAYVKKHARLAVRYPSRITDHWISPSCGDGGNRTPVLKSECCAPTGLAVRTAFVGLC
>SEQF2545_AGK83915.1 LIVCS family branched chain amino acid:cation symporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIHTHTLSLSFMLFSFFFGAGNLILPPLLGKHAGTTLATALLGFATSAVLIPIAGLITIAHAGGIVPLSERVGKRFAHLY
PAITLLVIGPALSIPRAGIVPFALAIAPLIHRANTTLLAQLIYTTCFFIVSYWLCMRPHTLSNTLGKVLTPALLVLVLLL
FLASFTPTLGPYLPAQGAYATHIPFSQGFLDGYLTTDALASLMFGNMILTYLHRTRYTTAPFPPTPANTLADMRTVAWIA
GVMLFFTYGVLAHLGALSARQLPHTVNGAHILASVSRHLFGKAGIALLGLIFTIACLTTCAGLLVCVSEYFHKRAPRVSY
LCWIRLFTISGFALANTGLERILAYGTPLLMILYPISLVLIGISHLERLIRIPRAAYRLTVWSAGTLSTCAVGTPLVAHT
RIGHVLNTLIHTLPLAQEQLCWLIPSAAVLILSTAHARLREKTCTPRGTLPLTDN
>SEQF2545_AGK83916.1 hypothetical protein TPFB_0267 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MASAHSFDLVDLDDEDYGTILAEDVEFSGTVRFEEPFMVRGVFEGSIESSGDLMVEEQARVRAEIVADRVVIKGEVIGNV
TAMSVVRVFPCGRLIGDVTAPEVVLESGCFFSGVCSMPESG
>SEQF2545_AGK83917.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIGFPCRGVALLVARFLLPVVFCFVCRGLCSQQSGLAFYRAGSYREAIRCCEEAIAQGSKDLEHYLVLAWALVAVGKYHE
AAQWALEGRAVAAHDPRLIEAQAEAFCHLGRNEEALRLFQDYIACAPNGARQTAAYYLMGEIYLRTSRFLHADIAFSVAL
QLDSLNDFWWARLGYARERAGDYRYALQAYDRALQLNRDLADARRGRERVLRYVFRR
>SEQF2545_AGK83918.1 putative MiaB tRNA modification protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFSVRIETLGCRLNHVESESLAALFLQEGFAVCRGNTSTAPVVLCVINTCTVTSKAEQKARRLVRLLLRTYPTAIALVTG
CYAQLEPASLEAMDDRVLAFPGKQKDALSLLPSCLRALLVQRGPAPIDQYVCGMRALLASLKKKIISLELTSEFPSQTHM
PTRNALPQLTGVPHAPRVSVSSFSEPTAVPRFALYAPRFLFHSRASIKVQDGCNSGCAFCRIRFARGRAVSLETHEVIGR
VQALEARGMSEVVLTGVNLSQYRSGSIDFAGLLELIVQETHTIHIRISSLYPESVTSAFLRAIAHTRVSPHFHLSVQSGS
DRVLRRMRRAYTRADIYQAVSDLRSVRGEPFLGCDIIVGFPGETEEDFADTQRMCKTLRFAGIHVFPFSARPGTEAFAMD
AKVPQRIAGERVAAMQQLAEKNYRAYLEYWNGRELCAVVEQSVARVLTENYLSLPIIERGGVAASAGSHVRIRVHNEGAI
LL
>SEQF2545_AGK83919.1 polynucleotide adenylyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLSSCEFLIRSGDSLLLEKNEHAVEREEGSVRVFPVCPLLREVSERFIRAGFCIYVVGGAVRDFLLNRSAHDWDLATDAP
PERVRMLFRRTVPTGIEHGTVTILFRGHSIECTTFRVESDYSDRRHPDSVCFAARIEDDLARRDFTVNAFAAALPSGEII
DVCGGYADLRNGLICSVGDAHARFSEDALRPLRAVRFAAQLSFSIEARTREAIIALRAHTARISRERVRDELSKMLCTPR
PSIALRLMEETGLLHTLFPALAQVCGRNEGEEKETQDSLQVSPQQRRDARTFAACAFAACDRVPAELAVRLAALLFPLAH
YRTLPASGTGAALFICPPALAEARELLRGLKYPNYLTAQVCHLVAHARFTPHECWSEGTLRRFVVTVGTTQLESLCVLRR
AYLADDDYRISAQPGVSCENAREGKKMQEQFEIFVTRVRRVAAQLPVHGIRDLAVNGRDLIAQGIPPGPTIGHILNALFD
MVLMQPSRNTRPQLLEHAQEIVRTMAQN
>SEQF2545_AGK83920.1 chromosome partitioning protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGKDKLGKGIDALLQESSDRYDVRDSGGVQTVHYLDPTLLQANPHQARRTFAQESLEELAASIREHGVIQPVLAEKNQDG
SWVIIAGERRTRAAILAGLNRIPVIVRTCDHEKKLAIALIENVQRENLNPLEEARAYQHIMDLGNLSHEELAQRVGKNRS
TITNALRLLKLPPEVQQSLSSRTLSAGHARALLSLTDMQLCVSVAQYVVTHALSVRAAEECVACLNRGGSLHDYAGARAH
TAASSPSPGGSATDITRLPPSSPSTDAQLDARIRNADIADIEQQLLEQLGTKVRISGNLQRGRIEITYFSQAELERLYGL
LKAH
>SEQF2545_AGK83921.1 chromosome partitioning protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGKTLVFVNQKGGVGKTTSAINLGAYLALAGKKTLLVDFDPQGNMSSGLGLARGLTVYDLLAGKAHINSVLRTTPVHNLF
AIPASIDLSGATVELVDEQDRELYLKKILAEVKDTYDFILIDCPPSLGILTLNGLAAANEVFIPLQCEYFALEGLTLLLQ
TVKRVQSGLNTALSIGGIFFTMYDTRTKLAQEVVKQVTTYFGDKVFNTIIPRNVKLSEAPSHGLPISSYDAQCAGARSYE
KLAREIVARDGQR
>SEQF2545_AGK83922.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLPYAEVILFLIKKHCIDCGEAFFGIVVLNALCLAGVGYSLLWHQGPGRSVLFVLVLATLYACLCAFCVVRGERGCDTLA
DTNLRVFTHALREVWLQSLWCALLQCVLFRTGKYVCTYYFARTHSVFTACGILSAWTYALACGALLWFVPVRARYRTHFR
QCVYLSARVFFEHPCITFLMVLYSMGVLALSVPMAFLFPGPCGIVLLWQDVLRTLCFRRAWLAAHEGRKAACAPPIPWEQ
LMCQMRAQSRAHTVGELFSPWKS
>SEQF2545_AGK83923.1 dCMP deaminase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGQREELVTRPSWDEYFMEVCHAIAKRATCDRGRAGCVIARDHHLLVTGYAGAPRGLLHCDEHGHQLRTVQHEDGTCTQH
CVRTVHAEQNALCQAARLGIGLEGATLYCTMTPCRTCAMLIINCGIVRVVAEKRYQTATESIMLFAQAQIALEHIYQNPA
EYGTPS
>SEQF2545_AGK83924.1 hypothetical protein TPFB_0274a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHMPLCCGAQHTLAGEFKHRSLRAEYTVEKQEKDIPYVSHAPVPAQWMQCLSPGTASV
>SEQF2545_AGK83925.1 WecB/TagA/CpsF family glycosyl transferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEQTQLVTRIEFLSVPLDVVREEYLCTVILSLLEKKEPQHIIFLSLWDVLKARHNHEFRTMVGRAALCLPTSYSIVRGAR
FLGLPTPIFRHPFQFIITLLNVMDTHYKSLYLFGGRGQSLLEAERNVHSTFPGLSVVGRFHGFYRKTLENNIITAIVKSN
ASLVIVGNGVPGGVRWIARNRAHFAGGIFVQDSEVIDIFSKRRKRPRAKELLHGRSPWGQTLHPLRWHRSVRYVWYIFLL
LFYRIFRTK
>SEQF2545_AGK83926.1 putative RNA methyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKQLLITAEPDSGGYVQLSGKDFHYMVRVRRARVGDTFTLRTQAGAQYSAVVSALDIHTRSLILHCTPMPPVDEKTQVTL
VLLQWMPRARVFDAIVRHATELGTARIIPIRGERSLIRDEKDTQHARLQRIVREARQQSGSAVNTRVDTLHSLLGALHML
EQEFPYPSAVRIYCSEKHVGGSFHELLWTGRSTHCTAHRTPTEPNAPHNTPDVRAQAVILAVGAEGGFSDTEERTLHDAH
FAPLHFRTNVLRVETAALYALAGAHLLLSEAALWNKRSW
>SEQF2545_AGK83927.1 C-terminal processing peptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQTVQDVYEFLRKYYVDEVDPHILYKGALEGMINSLQDPYTTFVESDSISGVNLQDTTKGFFGGIGVVISKSRTSTPGKP
AYVEVTAAIEDTPSWKGGIRPRDLIVKIGTMSTDTMTMDEVLKKLRGPIGTKVTLVVKRGTKIFRPFTLTRAKIEIPTVK
YAKIDPNIAYVRLIEFNPVTATRMVETVTELRRQGCDRLILDLRNNPGGLITAAVDVTSSFIPSGTVVTTKSRVQGHSIT
FSVNARAQKLPPSMPVIVLINRDSASASEIVSGALKDHKRAYLVGQTTYGKGVVQQVFDLNERESLKMTISRYYTPSDAN
IDKSGIPPDLEVRETEFTPEEEEALVSLFKSEKVKLFAEQNRTMNSERIKQYARGLAREFKLRSILVEKLIAQEYHRHNA
SFVYDLEYDEQLRKAVELIRTQDIHALVARTKTVKELQEGIQEKKKVS
>SEQF2545_AGK83928.1 bifunctional cytidylate kinase/ribosomal proteinS1 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHGGGGGRERSFVHPRTRCVAVRARTVLQCRPMGTVIIALDGPAGSGKSSVCRLLASRLGAQCLNTGSFYRAFTLAALRR
VSELAVQACSPSPDPDAAVGCAAVPHATNLDTSYAPLTAQKKVALFDEAYWVSFARTVALSYRAGVMYVGEENVESLLRS
DEVESAVSYFAAMPAIRAIMTGKIRSAVCGARVVCEGRDLTTVVFVDADLKCYLDASIEARVARRWAQGTSRLSKQELEQ
RMRARDAHDRARTVGGLRCAPDALYVDTSCLTIEEVCERIAREAHRRALWGGERSVENQEGKGTPLVPRQLQERYSFEAP
EPGSVRMGTVVQVNAGTVFVDIGGKSEGRVPVEEFEAPPKAGDGVRVYVERVTPYGPELSKTKADRLGLKVKLRDAERDG
TPVEGRIVRLTEKKSGFEVDLGAGMMAFLPISQSDCQKVDAPESLIGLTSKFYIERISQSKQHRGNDNIVINRRRYLEER
ARQAREEFFNSVHIEDSVSGVVKSFTSFGAFIDLGGFDGLLHVNDMSWGHVARPREFVKKGQTIELKVIRLDQAEKRINL
SLKHFQPDPWLEFENKFGVNDVVKGRVTKIADFGAFIELAEGIEGLAHISEFSWVKKTSKPSDMVKIGDEVECMILGYDI
QAGRVSLGLKQVTANPWEEIEARYPVGARFTRRIVKVTNAGAFIEMEEGIDGFLHVDDLSWVKRTRPADHELEVGKEIEC
MVIECDPQARRIRLGVKQLSDNPWQVFANAYGVGSTVEGEVSSVTDFGIFVRVPGGVEGLVRKQHLVENRDGDPGEALRK
YAVGDRVKAVIVDMNVKDRKVAFSVRDYQRKVQRDELSRYMSAPRGEDEGSFTLGDLMRQTSGK
>SEQF2545_AGK83929.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHEQRRGIVRVDRFLELHRRLLVGVLVAILGGLGLSAGCLLVMTRLRARASAEVTRIAREWDVLRKPDNTVSASGHEVEG
RGGSSIRAKEDALLARLESCASSPWRDGFAYAYAQACVADIFFARKEWEKAQQAYVRAAYGARRSYVAGVYYFNAASCAD
ERGRFEEARELYQRSARVQDFPLVPRALFNVGRMEEALGRAAAATAAYMQLYERFPLNGWAALGKSRAIAISVGGGRAQ
>SEQF2545_AGK83930.1 pantetheine-phosphate adenylyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKAIFAGSFDPPTFGHLDLVLRARSLFAEVHVLVAVNVQKRYLLSECERVDLMRQVLGDRPGVYVFPWRSLVVTYARDVG
ARVLVRGVRNATDFCQEFDLAWVHRALDAGLETVFLAAKPCYAALRSSMVREVASFGGDVSTFVPRVVARLLQEKFTQA
>SEQF2545_AGK83931.1 Fe-S oxidoreductase domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRADKGAVGTVAVVCAFDLSDYAFVPLCGTREQSCMKAVPGFVPCVEVRGCESTAGVGRRCAFERAVTAAYALPGCHQVC
VYADAASAAKVARFMQCATPIFPSLRVNVLDDMRVSAFFAHVARVCAEYAQLGEEPEAVFVLRADAPFIDSVASAQLYAQ
HREYLAEYSFADGYPEGLFAAVVAPGLFPILATLTQDAHICFDTSFIFESIKTDINSFDLETMIAPVDVRHLRLEFYTSS
KAQFLQCAAFTDITAENYAQLISAREHALRTVPAYYALELTRAYPLSSLYRPVSFPAQVENASLMPKEEACALIRRIADF
SERAVISLSVFGDPVLYPALCDVVREILKYPGLSVLIETSGLGWQESVVRDLCECARNSARTPFAIGWIVFLDAVSSGMY
SQVHRVSLSEAEFFLKEATEFAMQVHAQCPGVLWPQIFRMNENEKELEPFYRTWKERVGQVIVQKYDHVCGLLPDRRVAD
LSPLERYPCWHLKRDMIIFTDGRVPLCKEDVHCRHALGNAFQQDLAQIWRRGQDVYLQHVRAVHEGLCGQCDEYYTYNF
>SEQF2545_AGK83932.1 hypothetical protein TPFB_0286 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMSTIPIIFNEKNVAHTVVGGQLCPVASAFLGAVVLNRGVRWNRAEFFAQLTTLGIAPIVSVERSAAAPDVTGLAERFPF
VKFITPLECISVGEMINLGVAELDVMYVLVLWSDMRIDPQGMSQHIQDILRTNTHMCIAPQLCSSHSTVLPTQIVPALRK
SDFFTQPTECTTNHTPTIYPYDFVGIYHRDRFIQCGGFDFTIANAYWQNLDFGLRSYLWGECIEVNTQIRLFYEALPPQE
DASADSSYRIFYLKNLAPLLEKDRAFISGTQFFSFFRNSGLHLIEAYRLFRDAQKWVAVNRYRFKKTAARLVSEWEPR
>SEQF2545_AGK83933.1 cytidylyltransferase domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEQDRSGVAVIVQARVDSTRLPGKALLPLMGEPLIHYVLQATRVIPAETYILACDEHSKKDFEPVARAHGFYCISGSAED
VLHRFCIAVKAFEHSFPIRTVVRVTGDNPFLFHEAAAAALLRYAELNEPDYFTFTGLPYGSGVEILKARSLLLADRLPLE
AYDREHVGPALHRRPGIFVCVREPAAAAWYHPDVRVTVDTQEDFQRAQHMMEYVCTLQCPFPLSSDVILDAYAYARQVVV
FVPSVKIGQGAGHLYRAAYLVLRLQGRVRCCLYVPDRSLLCKLSTPFPEELIVDTVPADASLIVVDNFRTSTCEIELLQR
TAPVLALDEGGSGRLNADYLIDVFPVLQSPGRRSLAALTNVRDSAFIPLPETRKEQDLPVANGRFFPIPGVTTVLVVYGA
EDTHGRARSCAERIAALGFDTSVVVPGEASERTDGKVHIYPSLPHLKEHLHRWDVVVTHFGFTAFEAAAAGAAVLLVSPT
PYHFLLSSAVGFSVIRSADPAAHELWSQMQQGIIIPDVVTRHSQCRDLADEIMRVARGKKHCCPFCGEMVAVDVVGRALH
KTFQRCNECDMIFLSFVISDPVRYSESYFFEEYKAQYGKTYLEDFDQIRMHGARRMEEIERLYAEVFCADEGNSFAVDKK
VLDVGCAYGAFLSAAKAAGWNAVGVDVCEFAVRHVRDTLCIPACVATFPLLPECFDFVIRHSFATNRPQQVSVYIRECTF
SAVTLWFVIEHFQDLEAVLRKVADLLVPGGILAFSTPNFAGVTGMRFPHLFFAQSPCDHFTIWDARTVKKQLLRYGFTVK
KIVVTGHHPERFYPHKHLKSGGLKWKMLMALSKWFQLGDTMEVYAIKQGDAHGSASK
>SEQF2545_AGK83934.1 HAD superfamily hydrolase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSGAQVRLVVTDMDGTFLDSENNIPPENKQAVKCLHEKNIPFVIATGRMLPMVQEYVRQLQLVGPVVGYNGGMIREIKTG
KTIFQKCFAAEAFARVLEYGMAHRLDYLVYTSDSVYAPDYSVRIRAFHEYNRLARRGGSALIPIFPIEALSGDRQRQVMK
ILVQNFSPSDLETAAEFIGSLHGVHCEHSMPHLIDVMPEGVDKGNALHILCQYYGISLEQVCVFGDQRNDIVMFKAAGVS
FCMRNGHEEAKKHATYIAESNDDAGFAQALKRYGVVE
>SEQF2545_AGK83935.1 putative FMN-dependent family dehydrogenase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRSARSEYKCRLCARCDGYGCRGQLPGMGGVFNSANFIANCLAWKKYVPQRHELPVVRLAPMTGAVENVGYPDEVSFYY
RLIEAVSGTGVLLSVGDGCPDIKLQSGIAALRSFKKKAAVFIKPYVNKKIFERIEWGRDVAEFVGVDIDAYHIVTMRDKV
QLEKKTPTHLRAVRRFAKLPIVVKGIFAPRDVELVRELKPDVAIVSNHGGRVETARGSTADFLFEYGGELARCAGEVWVD
GGIRSYAHLCAARELGAQQVLIGRPFITALLKGGKGGVQLLVRNMTDRSVRCV
>SEQF2545_AGK83936.1 OOP family OmpA-OmpF porin [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCMMGSVFSRKGMLCVLAVWCAASAAYPLRLRYKFRKGDTHRINSLIREDVFVNDTLAHTAEITNRITVHVSEVRVAHGS
APDAARYVCHFMTSEKSPNNTFRWGRHYESIFWRDAFGVYDIDRSFFMPVVRNVPVFPDYDIEVGDTWEHEAEEAHDLRD
GFGIQTPFIVPFTVSYTYRGEVQRGSRRYHHITAAYSMSYESPKRTHGVQRNAKEGMYPVRTTGVSKQNLYWDNELGNIA
EYDDEFRILLYLSGGTVLRYQGTATAKNFAPERFDPARTVVELQETLKDLHMPDAKVRETEEGVTISIENVQFDADSASL
APSEYEKLRKIAELLRAFPDRELLVSGHAARRGSVQDQQRISEERADVVARYLQELGVVDAAHVYTRGCGAQQSIAPNDS
EDGRRKNRRVEITIISK
>SEQF2545_AGK83937.1 hypothetical protein TPFB_0293 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRMTRVRSLCLAYARCVRLGVFRCISLRGWAPYRAVETVLVQSALTSVERLHEMFRVY
>SEQF2545_AGK83938.1 ribose-phosphate diphosphokinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRCSGFTDLAIVACPGGEHFADETIKHLTRVCERKFHQRMDRLTDRYGLDSGSVIRDANFYRDLFSTELCAHDDVRRFNP
PHFKVDAQFICFLNGELKTQINECIRGKDVFIFQDVENHQPVLVNNGKSKKIFSVNDHVMMLIVTIDAVRHAGAGRVTLV
LPTYPYSRQHKKCGREGLTAGLLGSVYEYLGVSHIVTLDLHSREIENAFHRTRLENLHASYQIIRELAKIENLSDPDIPF
VVVAPDSGAVERNKFYSSGLKKPLAMIYKVRDYSVVAQNAKQSNIVEINLLGDVEGKTAFIADDMLGSGGTMLKAMEFLK
SRGAKQVIAAVSLPFFTGNALELFDEAYEKRYFSRIIGTNAVFHTQLSHKQWYTETDVSGLFARVIARIHHNQSLSSLLD
DRSIIERLLHARLSVAGTPRA
>SEQF2545_AGK83939.1 FGGY family carhohydrate kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGSGIFVADIGTSSLKAAIISQDGKVLQYQRVFFPQPVKAQDWVRSFFTVFERLRAVHHVIAITISGNGPSVVAVHKKSH
AEDQLILWNQAGASDPRCGVSLFLPKVLLLLQRLHFCARDVQFFLSSHEYLIYRLTGCAVTVLPERRYMPTYWTSESLRA
CALPETLFAPFVAPGSIVASYRGIPVVCGAPDFAAALIGTNTLHAGSGCDRAGSSEGLNVCVRLPPAIRSADARVRVLPS
LRADFWNVSFLIADSGSRFASYMRRTHAQGFGERMGQIMALPFQLHDAYPPTVVGEGRQLVEDLAFEVCAGLEYLESVTQ
LQPVYTVSGGQAKDSRWLQLKADVSGRCFVLPEIHDAELTGNAALACVALDFDADMQTAAQRLCRLKREFIPNRARHEQY
AQKRLLRAAREAQG
>SEQF2545_AGK83940.1 putative dephospho-CoA kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MREFCPLIGVIGRSGAGKNVVSRLLAERGCYCIDADARTRELLESYGDSIVERFQVAAAARGLSLRRKDGGLHSAHLGVL
LFSEPKLLQQHEEFLLPKVTRLLCEDIARAQAARPKAIVLNAPTLHKTELLQACSFVLYIWAPSILRMWRCKKRERVSFT
HLLRRFSAQKGFYAQSIAQNADTYTVANCGRVASLARKVDCILTRRGVLGE
>SEQF2545_AGK83941.1 sporulation/cell division domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHSDAQGCFRRVNMEQKRILWIVISLSVFMLIIFGVALLLYSPTYSSNSAGVTDVSSYVERGDVPEHPSVDPSLWLKNPE
KIPELGKTPAPTQRAIPDLTVVKDVPTARAKSLDVSPPARAERTDAAQDRKTSPASDTRESAESKGASKHARSDRASAKS
PPATRTRAPLVAQRDARVRGASTQPAAPSVLFWVQAASLSSKLNAERARGVLAARHMKAEIFTKRTGAGLRHRVRVGPFT
NRTEAVYWMKSIREIAEFSGCYVFQERVKN
>SEQF2545_AGK83942.1 ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGGGVMNGAVCVLSALIAVFTCFSCRPAVQDERAVRIAVFVPGFRHDSPVYAMLCDGVERAVTQERATGRSIGLDIIEAG
PNQALWREKLAHLAAEQRYRLIVSSNPALPHVLEPILRQFPLQRFLVLDAYAPQEHSLITFRYNQWEQAYLAGHLSALVS
ASAMRFANADKKIGLIAGQSYPVMTQTIIPAFLAGARAVDPAFEVDVRVVGNWYDAAKSADLARILFHEGVDVMMPICGG
ANQGVLAAARELGFYVSWFDDNGYARAPGYVVGSSVMEQERLAYEQTLRCIRGELPSAGAWTLGVKDGYVRFIEEDPLYL
QTVPEPIRVRQSALLRRIQSGELTLPVR
>SEQF2545_AGK83943.1 sugar ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMIAERGVRASARGVLSLHHIGKTYPRVMPRSKRGVWGMFGHPGRRAVDGAHTAHGPCSGARETDAAEHSVLSDVNLSFF
TGEIHALLGKNGAGKSTLAHILSGFCVPTHGQLRLDGKEQRFSVPFDALRAGIGIVHQQPVFAERATVFENVVMGSAALT
GVRWVRRAQVRERIDRIIAQWRMPLKKEEYVACLSADKRFFVSLLCVLFRNPRFIILDEPRCAPAQSRAVFFSHLEEFFV
RSSHAPRCGGGVIVVTHRFADALRWAQRISLIEGGKACSFLRTDLLDEYCSAHQVNECIQKVSCALMSASTVTSSAVSSF
SSLSDTQSCATVPRTSSARPWVLRVESLQVSKHADVPLTDISFSVAASAIIGIVGTPEDGVHVLEDILCGMHAGASRTHC
TGNILLQEHDQVWCLPLQRNTPSLLRAHGVACVPSNCIQRGASMQLTLFDLLVPYTLRTWRTRVRAQMRFVARLLAEEEI
YCDPLQPACTLSGGQLQRVILARELATRPRLLILAEPAEGLDSASEQRLLARLRQVAQAGTALVLLAREQHQAQWRALCT
ERFLLRAGTLCAEVSGTPSPSQDSHT
>SEQF2545_AGK83944.1 sugar ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRVINSCIAVLLGVAVMSAVIVLCSENPSVSLAAFFLKPFSTRGYIRALFHKAGLFVCMALGASCALKTGMINLGGDGQ
IYAAGFVTALLLREYWGVGFLLQWSVALLCALSVAGILACVSGILKAWLATSEMITSFLLSTACVPLIDALIITVTRDPA
GNLLATAPVHSHFILQQQTSLFGVPAVLTYASLVALAVGCFFSYTRVGYQFRICGKAPEFGRFVGFPVWATYVWGMVLSG
ALFGLTGFFSVVGLFGTCYVGFSVGMGYAALAHALIAHAHITVLVPLAFFFAWMETASEAAVLGAHLTVNVVLFLQAAIF
LLISAQWSAPWNAVRRGARRVYRFLVTVFCFRGEKHRTRRRHALSVHDTHHRRSRWE
>SEQF2545_AGK83945.1 sugar ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGVIGTTVIAILHRAAPLACAAAGALATEYAGVLGIFMEGVITFSSFCIAFFALVWGSYWGGLGITVCVVPLCLFFVAVG
TERMRANPFLTGIAVHFSAMGMSAFGASSMFARAAASAMQMDTAAHGVSFTHVSLAHTRVLPHPLWGTAVAFALVWVFHL
YLYSTNVGINFMHSGEGALALQVRGTDAARYRMVSWAVAGVCAVCAGGLLVLRVGTYTPQMAAGRGWTALAIVFLARKRM
MWCVPAAIFFSGIEHMCDVLQGTHVVPTGVLFALPYILSLVVFVCTRRTSPCRRGERRRSRLLFAYLQRVTCA
>SEQF2545_AGK83946.1 DNA mismatch repair protein MutL [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAPAAIPFPSEETTPPVIKIKAGSIRHECSVSMRFLKGSTLPLPCACRVDCPIGLHRTLLSNTMGPMNARAALALAMVFT
FQRLCAEERFVISTEYFDIIYTEASTESARILAKHADRYEEQISLMLNRVPDKKKRTTVVLYAHTQDAGGSFSSKPSRKI
IINDTRVPNLGLGSFKDSLLSIFYHELTHKISLDFFMPLLPPLFTEGVAVAFESNDGTQGRLHDPLTMHYLIQNKLENVS
PSWREVAELRYNYPHGMPYVYGGKFTEYLQKIYGKERCARLWQNSWRLFIRHRFWDVFQKDLGTAWNEFIDSIPIPEKVA
QPQLLSEREAQDHYGARSAAPTGFAYYDRDRHAVRFRDKAGGVRTLFSHDNTLHHLNFSEDGRYLAVSDTIDTWSERTHR
VRVFDTHSGSFSPEVYTGASEACFVGNGQKIVFVRVQGQYSRLTLKDRTDPTFEKVLYEAGPGLPFGALYAPAYAGDGTV
AIIGARGMERNLLFIPVDDRPMMQVPREQMPHAMRELQSQKIKGSWTLTFSWANMNMLSRLGFYDVSRHTFRLMDQDVSG
GVFAPVVYEALPAAVHEESAAEATIRGEEPVVRVAYTGRHRMHMSQYQRDDRALRERRVSLVPLHPAEAEEQSRPATLMV
NGEFIADVHEADRGRRYRAAQWMWPPTFSPRFVPPNSFSSLKDLGHTGLGVNMKFADPFGLVEVNLQSVSHFYPFFTSLG
LKSSFYVGKTTYALRAYHEIDTGGFRYTKLGGAFETLTNFPMQDDRNAFFVRTAVGVDSYSCLCANGGGNGNCCGNNGGQ
QCCACNGQGANGPHYYKSLESPFIQAQVEMGYSFSQRAERTGTNWFVADVTGVSLKLHVANSFDTGKTKDAVLVQTKGSF
RLPVVPLRVGVSAYVGYNAGWRGGKGNIPAEHPVYGFPGPTYLPKLAGVDGKEGSCNKSKSAGFGAEAVLTILDYDISIY
DPYLPVFYRNIVWNVSCEYVLNAPDFSSPKHLCVASTSLVLEFDLADVKVRAGVQYGFQLAETQSATPGFSTIFSMASQE
GSPVVCAKRATGAALRQNAGVGCLRSGKGFSMHETSYKPIHRLSPDTAKKIAAGEVIERPASVVRELLENALDAGATKIH
LEINAGGCALIRVSDNGHGMSPQDLLLCAEAHTTSKISSADDLLQLRTLGFRGEALASIAAVSRLHLTSTRSGPLAWHYQ
PKAAGTAAHVPPVPQGTEAGVLEPASLERGTVVRVEQLFENFPARKRFLGRQSAETTLCRSALIDVSLAHHPVEFRFTVD
GTHKLTLLSQQTRKDRCLETQMLKGDPALFHTIEGGDCSFHFHLVLSEPAICRRERRGIFTFVNGRRIFDYGLVQALVLG
SEGYFPNGTFPVACLFLTVNSERIDFNIHPAKKEVHLQDYAHIRHTLSRSVAHFYRQCTIAHYVRAEPAHAPATQGNAPT
HSSPPCTGVREEPAAPCAHTPRYESLFPLPVQHAHLLPPSPPHISCEHARDCTHPAPAAEGDAPVHNHTHTGAFKVLGQV
AGTFIAVERNNALYLIDQHAAHERIIFDTLQRNLGTAQILLIPYHIHPRSDEEARIMHRACTELSPAGFRFHEEPDGSWH
VTAVPLHWRGSEEQLAHDILYSGKNAHDILRHVLATCACRSACKDGTILDDATLHSLVEQAFALPQSRCPHGRPIWIVIG
RDELFKRIKRT
>SEQF2545_AGK83947.1 CTP synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDPAFIFITGGVVSSLGKGIAAGAIGLLLKSRGISVVNQKFDPYLNGDPGTMNPYQHGEVFVTQDGGETDLDLGHYERFT
DVPSSRFNSTTAGSVYRAILDRERAGGYGGATVQVIPHVTDEIQARIRAAAATTGARVVITEIGGTVGDIESLPFIEAIR
QIRRVLGKERCLFIHLGLVPYLPSCGEMKTKPLQHSVKELLGLGVQPDVILCRSERHITDAVREKLSLFCNVERRAIVEN
VTARSIYEVPLLLEAEGLGALLCERLRLFDTCCGGQVARNLGAGGAQSAVLGAGGTVRTDGGLHPAAGQGAEPDLTAWRA
MVRALYYPRRELTVALVGKYVSLADAYLSVSEALTAAGICHRARVDMRWIDAEEICSVQDAGHALADADALVIPGGFGVR
GIEGMICAVSHARVQNLPYLGICLGMQIAVIEFARNVLLLASAHSREFAVDTPHPVVDLLPGCVDTPTGGSLRLGQYRCL
LAEGSRARALYGRGEVWERHRHRYGLNAAYRARFEASALRPVGVDSDCGAVEVVEHGEHPWFFGVQFHPEFCSRPNRAHP
LFRALVAAGLERKDSRS
>SEQF2545_AGK83948.1 ribosomal protein S4 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVKRARGKIVRRLGINIFGNPKYTRLLGKKPAPPGKEHGVKQRAKVSVYGEQLKEKQKFRFAYGMSERQFRNLFAQAHR
MKGVTGNNMLSLMERRLDNTVFRMGFAISRVQARQMVSHRYFLINGKTANIPSMRISAHDVITTKNRKGIHSIIRHNLTL
SQGQRGSWLNVDEEQLSATVSELPRAQDIHPVGNIQHIVEYYSR
>SEQF2545_AGK83949.1 PASTA domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEGWRRCMDDGPLRVVVLTSFVILVVVCAVALCTFFVFLKSPDQVMTPHIVGKDFVSAAIEMQAKELYPRVQLRFSTREK
PGVVLEQNPPAGAIVKAGRYVDLVVSQQAVTTHVEDYRGLQVEEAVARIAAAEVERRISVKTPHLYRFSTGAAGTILEQD
PAPGAVLSADVELRFVVSKGSEREQTTVPLLVGYSLPELYRVMAQTALTLQFTVSPPSPSGERKDGEARGRTRANAQDYA
RVSAQDHDPGSRVEAFRAMQVQVLFPERGEAHEIYGILALDLPRYPYPMSCVLDVQYPGGVRTALAMFQHPGGRFTIPYG
LPAGATLFLTVGGKELFSGEVGALPHAGS
>SEQF2545_AGK83950.1 putative polar amino acid ABC superfamily ATP binding cassette transporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHCLMQVPSRRDGALRVQRCDGCVVWRSVCCALLVALLCLAVGCDSPDLLVDSDLSLSRVRVAKTLVMGVSDRTPPMCFR
YPNGEIVGFDVDLARAVCRVLGVRLIIRPIKWTLKRNALRCGLVDCVWTAFAVTARRRTEFLLSEPYLRTAQVLLVREGR
LHPDLAHVERELGQRMTGVSAVHTRGDILPMRSSHRQARIAVLRGGPVPGNEKWQFGFEPHGKVVWYRHRSAMLEALRTR
AVDAALVDLVEAHDAVHRQGAPLRVMRVPLGLSQYAVAFRREDRALRDEIQRILYRIAASGEAYRIAEKWFGVGQSVIGI
E
>SEQF2545_AGK83951.1 putative polar amino acid ABC superfamily ATP binding cassette transporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLWSCTPRARVFHAQDASFDEARVRGTLVVGVGRGLAPLVDAATFSAFSLPSSVVPPPARCSLLLQEARGYDVELLAQVA
RRLHMDVQVKVVHWDEKERALHAGVIDCIADGFTYTADHARRFALTQPYVRDVRVFAVLRQAPYATVADLHGKRLGVHAV
TDVEENDAYHALFGQVKTYAHYVQALTALSRAEVDVVALNLVTLCAVTPHLRRLYRILDEPIDTCEYVFAFRADARALRD
MVVRTLSQLQREGFVSALSKRWFGSDMSIIDR
>SEQF2545_AGK83952.1 putative single-stranded DNA-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAAICPSSTAKAGGGGIPVDPLNAVIVEGNVVPSASARAPEAAVCAFCIQTQRRVQGEGRVHTEVSYFEVEAWDALARVC
AQQVRPGVGLRVVGRLKQDRWQQEDGVRVQRVKIVAEHVEFQTPFVW
>SEQF2545_AGK83953.1 hypothetical protein TPFB_0312 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSSPVMHVWIGMLIGAANVVPGLSGGTVALLCGTWELLIAAIALDRAHLCRQWRRLLALAGGIVVGIGVCARFMRALYEA
FPHLTNAFLAGVLLASVPSLRNRVRAASVAAEHSVQAEGTARGHVGDAARRVWCAVRIIFFVLLGFVAVCAFSRMQHARD
ASSATAPASVQTTAVLTTAHTRGFVATVCAGALAAAAMLTPGFSGSLVLLLAGVYQPLLSVLSLRAVEQGGGVTGASVIS
RLCSAHVWGLLFPLCVGMGIGLLGAARVLRAWFRLYPVSAHACVCGLVLGSSVTLFPRGTAAGMQDQFTLFMGCVAGCVG
AFALAKVCAWGARDAGG
>SEQF2545_AGK83954.1 hypothetical protein TPFB_0312a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRAMRAGRQVQGVVSFCVCAGGRVRGLLDRAGGGGEVAWGACGGGVCCVWWWG
>SEQF2545_AGK83955.1 Tpr protein E [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGCMRWGSVLCVVVGVGASGGVLGQEFSPKLTGSATLEWGISYGKGVGSHGQAPGAVMGTGPYNLKHGFRTTNTVGVSFP
LVMRTTHTRRGQHPALYAELKVADLQADLSQGKAGFAVKRKGKVEATLHCYGAYLTIGKNPTFLTNFARLWKPWVTAQYQ
EDAVQYAPGFGGLGGKVGYRAQDIGGSGVSLDVGFLSFASNGAWDSTDPTHSKYGFGADLKLMYARAGHPLCTVELASNV
TLEDGYLIGAQKDANNQNKDKLLWNVGGRLTLEPGAGFRFSFALDAGNQHQSEATAAMRTERTRERAQEVALAIFTHAAQ
EQAKQAADTVGSTIDNSVQVARSVITQIAEGAVKQAHDQIKRTNGTQVVNIDVTVPVNVRQSPVRQPDLPSLTAIAAQLP
NVTKLFFLSAGAAAARPIIGQITGVVQNVITQQVQARVAQSTAVAIQQVSVFNQQTVAAEKANTQKHTINGKSYAAHIGS
LVSLATNRALPTIQQRVKQAVQENIRRINAVVQQKAQTLTSSQELEKAVYSLFVPTFENLVLGAGALLALLDMHQIAVDA
LFTAQWKWLSSGIYFATAPANVFGTRVLDNTIASCGDFAGFLKLETKSGDPYTHLLTGLDAGVETRMYIPLTYALYKNNG
GTAVRGIQEKEYIRPPVVGKAWCSYRIPVQDYGWVKPSVTVHASTNRAHLNAPAAGGAVGATYLTKEYCAQLRAGISASL
IEKTVFSLDWEQGMLSDVPYLLVSECLTQGIGRIVCGVTLSW
>SEQF2545_AGK83956.1 hypothetical protein TPFB_0314 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRGCRVGQRTGTVGVRVFPVGLCALSLQARDCRGMGRRSVWGVLMFGCMLPGAAARVSLSPKLGVYGDARGGSDLWGIC
IQAPTMPDTENQAPPRYAPETPLVGLDVAFRAENGFLLQLTVDAALTRLMFCGRCLAGYSFRPGEGSTHLSVAAGFECTA
LIYNGQHYLIVPKAGILPKSTSGCTEGGWRLPRSVLGLLTHQKDEGAIHEESSLEGICQNYAVPVQLGVQHYFGAHWGID
ATATVSFGIDTKLAKFRIPYTLRVGPVFRT
>SEQF2545_AGK83957.1 Tpr protein F [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRQVMQAGVLAGMVCAASGYAGVLTPQVSGTAQLQWGIAFQKNPHTVPGEHTHGFRTTNSLTISLPLVSKHTHTRRGEA
RSGVWAQLQLKDLAVELASSKSSTALSFTKPTASFQATLHCYGAYLTVGTSPSCVVNFAQLWKPFVTRAYSEKDTRYAPG
FSGSGAKLGYQAHNVGNSGVDVDIGFLSFLSNGAWDSTDATHSKYGFGADATLSYGVDRQRLLTLELAGNATLEQHYRKG
TEDSTNENKTALLWGVGGRLTLEPGAGFRFSFALDAGNQHQSDADADCRLPATGSSREKFDRAFDALRVEQYYVKDKYLE
FLLGQMAESSILERVGLALTLQDGTLVSTLTKVATDSGDRFIQMALVKLLPQRAQAEQGLREIVAPSQSDIVLIMLLTWL
ERARLDRFNADALLTAQWTYVSAGLYGATAGTNVFGKRVLPALQSWHFDFAGFLKLETKSGDPYTHLLTGLNAGVEARVY
IPLTYIRYRNNGGYLLDGVVPPGTINMPILGKAWCSYRIPLGSHAWLTPHTSVLGTTNRFNVINPAYTLLNERALQYQVG
LTFSPFEKVELSAQWEQGVLADAPYMGIAESMWSERYFGTFICGVKVVW
>SEQF2545_AGK83958.1 Tpr protein G [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGCMRWGSVLCVVVGVGASGGVLGQEFSPKLTGSATLEWGISYGKGVGSHGQAPGAVMGTGPYNLKHGFRTTNTVGVSFP
LVMRTTHTRRGQHPALYAELKVADLQADLSQGKAGFAVKRKGKVEATLHCYGAYLTIGKNPTFLTNFARLWKPWVTAQYQ
EDAVQYAPGFGGLGGKVGYRAQDIGGSGVSLDVGFLSFASNGAWDSTDPTHSKYGFGADLKLMYARAGHPLCTVELASNV
TLEDGYLIGAQKDANNQNKDKLLWNVGGRLTLEPGAGFRFSFALDAGNQHQSAQDFQNRTQRAQSELTALSNNLFQGESQ
KQEAWLDEYAKKVLDAVTAATETALQSRGNAYITAVSNVKVTPPVAATLLTNLKVFITDPPTPSPLPALPAFSLMGQVLL
QYDAEQVVKGFEQVQTQIVAEINQKVQAAVAQSKAAAQAFINGLTKAIEDVADALLAPHKGNPMSLFNLPDQQKLLKDDL
ADLIPKLTAEATKFFTEGQTFVTEEVKKKTDALDAGQQIRQAIQNLRASAWRAFLMGVSAVCLYLDTYNVAFDALLTAQW
KWLSSGIYFATAPANVFGTRVLDNTIASCGDFAGFLKLETKSGDPYTHLLTGLDAGVETRVYIPLTHDLYKNNNGNPLPS
GGSSGHIGLPVVGKAWCSYRIPVQDYGWVKPSVTVHASTNRAHLNAPAAGGAVGATYLTKEYCAQLRAGVSASLIEKTVF
SLDWEQGMLSDVPYLLVSECLTQGIGRIVCGVTLSW
>SEQF2545_AGK83959.1 sugar ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MREKWVRAFAGVFCAMLLIGCSKSDRPQMGNAGGAEGGDFVVGMVTDSGDIDDKSFNQQVWEGISRFAQENNAKCKYVTA
RTDAEYVPSLSAFADENMELVVACGSFLVEAVIETSARFPKQKFLVIDAVVQDRDNVVSAVFGQNEGSFLVGVAAALKAK
EAGKSAVGFIVGMELGMMPLFEAGFEAGVKAVDPDIQVVVEVANTFSDPQKGQALAAKLYDSGVNVIFQVAGGTGNGVIK
EARDRRLNGQDVWVIGVDRDQYMDGVYDGSKSVVLTSMVKRADVAAERISKMAYDGSFPGGQSIMFGLEDKAVGIPEENP
NLSSAVMEKIRSFEEKIVSKEIVVPVRSARMMN
>SEQF2545_AGK83960.1 hypothetical protein TPFB_0320 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPPVPARGRPSSSSDFCLYGMAVVNGFCVQDIPYGSRVVLPGRMRSSSAGA
>SEQF2545_AGK83961.1 sugar ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPYAVEMRDVTVRFPGVVANDCVSFGVQTAEVHALLGENGAGKSTLMGVLFGTCPKQSGELFVDGRSVCIRSPRDAARHG
IGMVHQHFNLVHNLTVSENIVLGVEPRARFARTDVRAAHRAVGELCERYGLAVDPYAKIQDITVGMQQRVEILKMLYRDA
RVLIFDEPTAVLAPQEVQQLMQVIRRLAREGKAVVLITHKLSEIKAIADRCTVLRRGACIGTVSVAEVGEERLVEMMVGH
AVDYALPRASRKDGACVLEVRSLSVGARRVTSGQMSADASPSAAPRAYGVRAVSFQVRCGEILCITGVDGNGQSQLLEAI
AGLVPVSEGQILLDGCEIQRTSVRERVLRGVSYIPEDRRKHGLVLDFSVEENMVLRSYFRAPFARRGILDRRVIAQHAHA
LAKKFEVQSGALGCAVRARTLSGGNQQKVIIARELHRAPRLLIAAQPTRGLDLGAVQYVHRAIVAERNRGGAVLLFSLDM
DEVLALADSIAVMYEGEIVGTVHACDATEQELGRLMSGMRKKETAGKKTGVQG
>SEQF2545_AGK83962.1 sugar ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRRNRARARASHEWDAEKRDCGQKNRGTGVIARLRGCLVHPKYHALLIPCLAVILGFAVGAVVMAVSGLHPKYILIALVR
SMFGVNVQAFGTGRSVWNFRYMGEGVVTCLPLILTGLAVAFTSHMGLFNIGAEGQLVVGSVCAVCVGVLWHEHLSFFTIP
AAVLAGMVGGGLWGLIPGVLRAVCGISEVVVTIMLNYVGLYGANFVVTALPGSDLMRTVSLPPAATLHSDFLSRVSNGSR
LHWGFLLVIAALVSFKFLIEKTTFGYELRVVGASAEAARYAGIHIRRRVMLATSISGMYAGLAGVLLAIGTFSYGRVLPG
FEGYGFEGIVVSLVGRNTAWGCVFGGSLLGSLRAAGPLMQLNGVPKEVSVIIVSAIIVFLSMHNGIRAMLVRWGRQGAHV
>SEQF2545_AGK83963.1 sugar ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNTFYSMVALTLVFSTPILITALGGLFSERSGVINIALEGLMMFGAFSTATVTVLCEPYTIAAPWIALGVGMAVAASVAL
FYAYLSVRLCSDQIIAGTAINLCATGMTVFFAQVIFGQQGTQAYSRGLVKTSYGFFSRIPVLGPMVFTHTYPTVYLGFVL
VALAWYVLYRTPFGVHVRATGDQPYAVDGAGLSVFRLRSAAVVISGLCAGLGGGVLILTQDIQYTVYSTHGTGFIALAAL
ISGRWHPFGVLVTSVLFGFSQILNVYATSVELLKHLPIELFSALPYALTVVVLLLFGGRGEAPRAIGQPYDRARRY
>SEQF2545_AGK83964.1 putative outer membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVLPSVRRFECSLFVVLVLCALAVFDPLSGFVQQKLAGVQRVWLGLVEEYSGLRFQYDSLSPSVLRAVTLRNVRVREAV
RGEQVAVFSKIVVAYNIFSLFGSNPVRGIRALHVHDGAVDVDLYRHRHVKEKLQKLFSKDGEMASFFADLREIDVRVHNT
AVTVRSDSRRAHLSVSQGRFSFAETGASFALSCEAEYVDTRSSSWGPLYTHLDASGVFETSFTSGSATLELAPPSGSFFS
VPTLTLVAIYADDLFKFHTARGIYPMEVSGQWNTATGACEASVSCENFRPLKWARLRDTHVPAQGMQELSVSGNVQVGYT
PIEQWRWSADVHAHTPYVVLAPGYQLEDVVATLQAHGDPARIQVEKICARGSNLDVDGAFELTLDRWIPSGVLTVHRLPL
LSGAYLSAQVRFRPQGVGFVCTVPRIQVGEAFLEDVALSVRVDPAKTDFRLVAADSTGRYECDGSYLAANAGQSRFLEAH
VAFESVNVGALYQMVAACTSPQGASTLVTRALVPLQSTADFYVSSDFRDISYNCVRLVLASDEIADLYAMLSVQGTAASF
SVTDISLLCKGLEVQGNVMANFEHGGDALFESVLSINSVPYRTRGVYADRTLTVYGDYDFSVVASFDERAGVTGTFQVQN
LPVPLSQSLFDCDSSFAMRSAHSWEVRFHHLHLRSGAVAAGGSEQIETVLRLAGVANQAGALFDQVFFGSRDRYLAGTAS
FAVVPRTGQHEQARYETAVRLASEDAQEQVQLNAQVTVGEHVYVDSSGRIDNVDVGRFVAGQGERSRVTGSWTVLGTMQD
MSGQVQVDSLELIAKGVPFHLRGGCALDDGTLALLPTQVTWGSHQFADLAGEWVPGQARAWVRTTYSGAFEGQPTHATCT
LTLAGSPVDSGKATSALRTSFLTPFLQTHSQYTISAEFEHWRIATYEGEKNRILVVRDPGVWALYAGEHDEITGFMLDDG
SVSLQVAQSLPVHFFLNGSLSAQQVDVQIQDIFVDLARVWAFTGIRHVRVHEGVAVGNVTVSGTRARPVFEGKLRGKEVV
ASAPGYAPERFGPGSIDIVAHGSTLIVPYTEFPGPTARLWGECVAQLNGFYPDEVVIKCGTVGDALGAIQTDNLLFAMDG
SAGCDLELRITPQLLSINGKARFDRGYFLLNFSGIEEFYTKYADSAQNFQMNLLLSAGNKVEFRWPRSDFPILRTLLHAQ
EPFEFIADPVSGSFYVRGFAHLKGGEFFWIKRNFYLREGTIHFARDTQTADPRISFRAELKDRDTQGRPVSLILSAEDQV
FSKLAPKLRCDPPVSEQELAKILGQVVLGDLTEENIEQNVASIASDILTQWGIMKRVEDKIRSFLDLDAFSFRTYVLQNA
IFGNLFNKDRSKPLTVGNYFDNTSLYVGRRLDRAVYADALLHLSQYDPLAPNNLGIKKPAAGSLLFRPELGLEFATPFFS
LRWASTPTRLDSLFVSDTSMRVSWSFAY
>SEQF2545_AGK83965.1 outer membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLKKASAFLIASCCVMSLAWAQANDNWYEGKPISAISFEGLEYIARGQLDTIFSQYKGQKWTYELYLEILQKVYDLEYFS
EVSPKAVPTDPEYQYVMLQFTVKERPSVKGIKMVGNSQIRSGDLLFKILLKKGDIYNEVKMKVDQESLRRHYLDQGYAAV
KISCEAKTEAGGVVVQFTIQEGKQTVVSRIQFKGNKAFTESVLKKVLSTQEARFLTSGVFKENALEADKAAVHSYYAERG
YIDARVEGVAKTVDKKTDASRNLVTLTYTVVEGEQYRYNGVTIVGNQIFSTEELQAKIRLKRGAIMNMVAFEQGFQALAD
AYFENGYTSNYLNKEEHRDTAEKTLSFKITVVERERSHVEHIIIKGTKNTKDEVILREMLLKPGDVFSKSKFTDSLRNLF
NLRYFSSLVPDVRPGSEQDLVDIILNVEEQSTANVQFGVTFSGVGEAGTFPLSLFCQWEEKNFLGKGNEISVNATLGSEA
QSLKLGYVERWFLGSPLTVGFDFELTHKNLFVYRAGSYGNGLPHPYTSREQWASSPGLAESFRLKYSRFESAIGAHTGYQ
WYPRYAVIRVNGGVDFRVVKNFYDKDNNQPFDQTVKEQLNWTSINSFWTSVSFDGRDFAYDPSSGWFLGQRCTFNGLVPF
LEKEHSFRSDTKAEFYVTLLNYPVSAVWNLKFVLAFYTGVSVQTYYGRRKSENGKSNGVRSGALVIDGVLVGRGWSEDAK
KNTGDLLLHHWIEFRWPLAHGIVSFDFFFDAAMVYNIESQSPNGSSSASSSSSSSSSSTEGLYKMSYGPGLRFTLPQFPL
KLAFANTFTSAGGIPKTKKNWNFVLSFTVNNL
>SEQF2545_AGK83966.1 outer membrane protein H [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKATLTFVFMLLTSLLQGQSQHITRFAVIDAARIYSTFWRDSRVLRDYESKKARHQGEIQKMSDELVELRQKKVDAQMQQ
NIASVQKYEVLIASKTALLLEYSKTSNDELTALRKTLIADDAFYAKLYAAIRRIAESEGYSIVLDLQKNAGILWYSHSVD
ITEDVLRELSSS
>SEQF2545_AGK83967.1 DNA mismatch repair protein MutS [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRSLASDTPLMRQYHAIRAQHPDAVLFFRLGDFYEMFDSDALHVSTLLGLTLTKRNGTPMCGVPVHTARTHIARLLKHGK
KVALCEQVSHPVPGELTQRKVIEIISPGTAVEDDFLSQGFSQYLATVCASDATVAFSYLEVSTGAFFITSFPRAEAADAL
QKEFGRVQPSEVLLSASVLRSLPELAAILSLYPRLVRTTGADALFNPEHTKNRLHHCFRTRNLDCLTLLPHSPDLAAAGA
LIAYLEETTRHPLSHVSAITRYHIHDFVEIDDATRKNLEILQNLHDSTHAHSLFETLNYTHTAMGTRLLRYWLHHPLRSQ
EEIQKRLSAVVFFHHRPHILKTLRATLSCVRDVERLVARVALEKAHGRDLLALKESLRAILTFRSLERESPFPPDLLPSE
GDTPVLQELYGLLEQSIKEDCPVTLSDGNLIKRGFSASLDELHRVRDNANEILKQYLAEERERTGIGTLKMKYNRMLGHF
LEVSKGHLSAVPAHFIRRRSLSNADRFTTEQLSELEAKLARAREGLVSFEQELFADIRRTVCSHTQLLRTNAARVAQLDV
LQSFAHAALQHGWSQPVFIKDGALRITGGRHPVVELHLPSGEFVPNDLTLSSSEHAVLPRFALITGPNMAGKSTFLRQTA
LICLIAQVGSFVPAEKAELTPVDRIFCRVGAADNLARGESTFLVEMSETAHILRAATRDSLVIMDEVGRGTATEDGLSIA
QAVSEYLLHHVRAKTLFATHYHELSRLAHPQLEHLKLDVLETDNTIVFLKKVTPGSCGSSYGIYVARLAGLPESVLARAC
ELLKQLQQRAGSAPRASAAHEADAVAQTEAVHAHKAASKPCAQRVSADLFTQEELIGAEIASLNPDAITPLEALTLIARW
KRSLRGSATQQSSAMTKRKG
>SEQF2545_AGK83968.1 hypothetical protein TPFB_0328a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYLVRSTRTQVRTECGIIHVFLSSGRQNIVRSVSSAKNGQNAARRMPDTRRA
>SEQF2545_AGK83969.1 glycine hydroxymethyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNNSALRAYLSTRAPDQIHSAFVAYLANLDLVAHQFPQIASDIVQELIDQRSYVKLIASENYSSLAVQAAMANLLTDKYA
EGFPHHRYYGGCQNVDSIESAAAAEACALFGAEHAYVQPHSGADANLVAFWAILSRQIEMPTLSSLGVTAATHLSEEQWE
VLRQKMGNQKLMGLDYFSGGHLTHGYRQNVSGRMFRVVSYAVDRDTGLLDYAAIEAQAKRERPLILLAGYSAYPRSINFR
IFREIADKVGAVLMADMAHFAGLVAGGVFTGDEDPVRWSHIVTSTTHKTLRGPRGAFILCKKEFAEAVDKGCPLVLGGPL
PHVMAAKAVAFREARNAAFKTYAHAVRDNARALADACIQQGMQLQTGGTDNHLLLLDVRPFGLTGRQAERALIDCGVTLN
RNSLPFDPNGAWLTSGLRIGTPAVTSLGMGPEEMKRIARLIARVLGAATPVRTKTGALSKSAAEVPGEVRSSVCSEVREL
LARFTLYPELDEPFLRAHFTRRPADKTPADEGT
>SEQF2545_AGK83970.1 AAA family ATPase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHSGQQLLEKNSIIISGLPPWAQELSKKYCSKTVNLYFVHGNIRDFLPHRDIQGSFSFVRINDYISEVIFGNRDIIVFYD
KSAGLTFCLQEMLSAYLERMHAQYPTEALADFLSRDPVKAFAYLERYFIMNMKQNKRMVLIIDYSESLVPSEDIANLSET
DRYCFVTLNRWANDPVFTNEDISVVMLTENITDINSRFTASPSTVKIHIPLPNEETRIRFLEYLKTQEEILVLERGLNTE
KIGKLTSGLNLVNLHQLAAETYQTIDANGKPEDNISRLSHTDSATLQFLKRKKQEIIEHEAGGLLEFVDTSCDLSYVAGN
VFVKKRLYNAVRAIKQGRADVLPMGYLISGPIGTGKSFMVSAFAGEIGIPMVRLCNFQATQPGITQSNLEKTLNILKALT
PVAVMVDEADAVFGRRNAPAGESRIFAQIAGFMGNTQHRGNIIWFLITSRPDLLPIDLKRQGRAEEHLALFYPETTKEKT
EIFEALKKKLRIKLKDVHVPAIIRRIKFAVSGSDLEAILVRAQLTAAMESRTMVTTQDITRTIEDFIPPAYPHEIELQNL
VAVLECTGKEMLPARYQHLDRSKLVADIRELKLLMGEK
>SEQF2545_AGK83971.1 phosphogluconate dehydrogenase (decarboxylating) [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGADIGFIGLAVMGENLVLNIERNGFSVAVFNRTTTVVDRFLAGRAHGKRITGAHSIAELVSLLARPRKIMLMVKAGSAV
DAVIDQILPLLEKGDLVIDGGNSHYQDTIRRMHALEAAGIHFIGTGVSGGEEGALRGPSLMPGGSAQAWPLVSPIFCAIA
AKADDGTPCCDWVGSDGAGHYVKMIHNGIEYGDMQIIAEGYWFMKHALGMSYEHMHHTFTRWNTGRLHSYLIEITAAILA
HQDTDGTPLLEKILDAAGQKGTGRWTCVAALEEGSPLTLITESVMARSLSAQKQARCKAHRVFGSPVKVSKAETLSAQQR
EELVSALEDALYCAKIVSYAQGFELLSHTAKRRGWTLDFSRIASLWRGGCIIRSGFLSKISAAFAQQHDLENLVLAPFFA
EELKRACPGWRTIVAESVRQALPVPALSAALAWFDGFTGAALPANLLQAQRDYFGAHTYERTDAPRGEFFHTNWTGTGGD
TIAGTYSI
>SEQF2545_AGK83972.1 hypothetical protein TPFB_0333 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAMSTGSGTRAHLMRAKVIFKYPDRLRLDFSSPAEQTIVFTGDSLTIYLPTSRVALVQSVAKDDTVSAASLASPHGLALM
KRFYTIAYETSSSPVPLGPDSGEMVVALVLNRKSAAETFKSLRVLVSAHTKLIRRIEAWPLSGEKITFDFSHYRLNVGIP
DTRFLYDVPPTANVVHNFLFAD
>SEQF2545_AGK83973.1 HTH domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPDIGELLKTTRERKHLSLEQAAHETSIARRYLEALENDEYDVFPGEPYILGFLRNYCEYLQLDTEQCIARYKHLKIQEM
SLPTETLLPSKRWGSFPLLKGVACVLFLGGVLGVYYARHRALGFLSRIVFFGRAQRTPRELSPPDATGAVRETVSLSSAQ
HEERARRTRSSASRYTLAEEKFEHTVFPGDVLVISSGGNAYELTVSRTTPHLYLDTPIGTQVISLGQRLVMDLNTDVQPD
VEISVEDIEAHQADGGARVRVFTGSLVQTLRDRSAQSFVPTSGVNVSGQTGVAAGARYQVLFEGGVAYPVTMNATFRSYC
LFRYEADRTRREERYYQKGEQLTVQANNGIRVWASNGNVVQLQIVAGGKTVDVGLSRPGEVLVKDIKWIKDEDAGRFKFV
VMEVD
>SEQF2545_AGK83974.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAITTAGDICALYPLCPILLHCSTLMHLSPLRNTPHVLHAAAAVTEYAFVLSTLVFPSFCFSLPSPFPFPEGEGGAFYVR
LFLNALSEEVLFRAYIPERLCHHATSCTARACGEVLSVLLFALAHRPAGSATLFAGAAGAALRVLFVREKKRSGSRARAS
ALCAAVHALWNAYAIAAAAC
>SEQF2545_AGK83975.1 DNA-T family bacterial competence-related DNA transformation transporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLSTNAYSVTAAAACSTCGVLRKGERCISVEQCNRIGQRGYRAHISPAVVMAIAAVGGFYGTHVYEVPFPYAFFGAVQAC
VLCIGCLLVRSGVRFFSRWGAVRIWRRWGIAYTSVCRCCNTLFFVFCGLCVACVARTSLMVQQAPLQTLAQPQKLRVLTI
HLLQEPKPAGTRFRVRARVLGAGYIDGASFSARGVCTVLFPAEVILQQYATDMTDDADARVCQYYARGLRCQIRGRFASS
APKLFISSSTPPRFVGWSSYFAQMRAQMRVALMRFLSPWGRAGGLLLALLSADSVFLSDEMRVAFRHAGLAHVLALSGMH
LSLVGASATFLGRFIGTRHRGMQGAFFAMLVFVWFAGISPSLARALGMTLVLMGGQMAYVRVGLFSVLCAVLSIHMLIAP
HDVQTLSFMLSYGALAGIVLLGSEITEMMSGLIPRPLASLLGTSCGAQFFTAPIVLSVIGYFAPIGVLASCVVSPLIALF
LIGGSVALCCSLAVPAVAPFLSWGVYFFGEGLCAVVRFFACAPLVYVQSACGHVCAALFSFLLGGGLLEAARRVRVHKDT
YVLPEL
>SEQF2545_AGK83976.1 rRNA dimethyladenosine transferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCCPNYNSARALAQFLTERGLRMHKKWGQNFLLDPVLRTQLVKILAPERGERVWEIGAGIGAMTALLVQNSDFLTVFEID
RGFVQTLRKLFDAHVRVIEGDVLQQWHAAAAQEQPACVLGNLPYNIAARFIGNTIESGYIFKRMVVTVQKEIGLRMTALP
AQKWYSYFSVLCQWQYEVRVIRNVAPVCFWPRPHVVSQALVLTKRNAVPSCVDPALFLHVTKTLFSARRKTVRNNLLTWQ
KRMPGGAAVCVEELCARAGIDARARAEQLSIYDFITLSDTLRALL
>SEQF2545_AGK83977.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARVYILFFSVFFVFPLFSEDAARDVEPSDAPVPYEDTEFSLWQKELYRFEALSIGAFPIVTLLSFITYDIIRLIQQWST
KPPTWWALIIPGAELPPLSTKERAIVFGVAVGISVTIGLIDVTYRAVKRAIHRRSLERSQLVPDPIELVPLDSFVEGTDD
ST
>SEQF2545_AGK83978.1 pseudouridylate synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSYSCSAESTSVCSVHFSVFRIPGATCRCDVFCAEHVFFCARSQLKRIVRALCVNGHTAKFSRPLHVRDRVSFEWVRSVP
PALIPENISLSILFENEDIIAVNKAQGMIVHPGAGHWTGTLVQALSFYRVYRARFEDEFSRQFQKGFPDFFSTLRQGIVH
RLDKDTSGVLLTSRNMHAHEALVRSFKKRQVRKVYLALLQGVPARGVGVIETTIVRDRRRRTRFVASEDFSKGKYARTRY
KVMKICGACAFVQFLLDTGRTHQIRVHARYLGCPVVGDPLYGSRNICGIPTTLMLHAYAVRFVLPRTKKRITLVAPIPLR
FVRLIHRLSVR
>SEQF2545_AGK83979.1 bifunctional dihydrofolate synthase/tetrahydrofolate synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSDLSNVHQFSFPARIAASSVPHIIVRPSAHGVSHIPVHSFQDFYAWVERIRTLEKMPPSGTPPLHRMTALARALCNPHN
AYQSIHVAGTKGKGSSARMLAAILNEIGFNTGLYASPHVMDPRERITRAGVFFSPAEYASACTHVYHTVKKTENLRDYGQ
ATWFELITLLAFMLFAQQRMEWSVFEVGLGGRLDATNIICPSICLLLPIEQEHTRILGTRIKSIAKEKGGIIKPYTPIFC
FDQPEDALHVFKHIAREKHAPFFYLPDMVTHIESSIKHFTHTATLSFNAAHPVGRLFARNIHCTLALCDIVQAKNAALAA
CAAKYLFPTVSETLIERGLSRAYVPARFEIMQEDPLIVIDGAHTTQSIRCACRTFSSLLPSAQYILLFACAADKAVSQFP
PLFSHAASEIFLTIPGTSKHADIQKTYHAFRTTFHQTVPIFWSEDFASIISRALYASFAQRKALLAIGSFYLAAEVKRIY
ARTCHTLPNR
>SEQF2545_AGK83980.1 UDP-N-acetylmuramate--L-alanine ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRGTLPKDVSGIKIHMIGIKGTGMSALAELLCARGARVSGSDVADVFYTDRILARLGVPVRTPFSCQNLADAPDVVIHS
AAYVPEENDELAEAYRRGIPTLTYPEALGDISCARFSCGIAGVHGKTTTTAMIAQMVKELRLDASVLVGSAVSGNNDSCV
VLNGDTFFIAETCEYRRHFLHFHPQKIVLTSVEHDHQDYYSSYEDILAAYFHYIDRLPQFGELFYCVDDQGVREVVQLAF
FSRPDLVYVPYGERAWGDYGVSIHGVQDRKISFSLRGFAGEFYVALPGEHSVLNATGALALALSLVKKQYGEVTVEHLTA
LRKVLALFQGCRRRSEVLGEVRGILFMDDYGHHPTAIKKTLRGLKTFFPERRIVVDFMSHTYSRTAALLTEFAESFQDAD
VVILHEIYASAREVYQGEVNGEHLFELAKRKHRRVYYYEAVMQAVPFLQAELKEGDLFVTLGAGDNCKLGEVLFNYFKEE
V
>SEQF2545_AGK83981.1 cytidylate kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSNRCDVSGNKAVRIAVSGASGCGNTTVSALLAERLGLPLVNYTFRNIARELGISLSEVLERARTDNHFDKAVDARQLCL
AMRSSCVVGSRLAIWLVKDAALKVYLLASLKERVKRVLQREGGDVQDVERFTSMRDAEDMSRYKKLYRIDNTNYSFADLV
LNTEGCDQETVVSIIIEMLRARGIAW
>SEQF2545_AGK83982.1 putative A/G-specific adenine glycosylase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVGLSQSAGDIEKFQNAILDFYAQQGRDFPWRSTCDAYAILVSEFMLQQTQTERVCPKYAEWLHRFPSLESLACAPFAHV
LQAWIGLGYNRRARFLHQSAKLIVERYCAVVPDDPSELKKLPGVGDYTAAAVACFAYNKATVFLETNIRAVFIRFFFPDT
HQVSDRELLSLVRCTLYEENPRRWYYALMDYGAVLKRKITNPNRRSKHYVKQSPFEGSLRQVRGAVLREISGMQHAVREK
TLFAKLSFEHERLSRALDSLVSEGLVVKTEAGYSIAD
>SEQF2545_AGK83983.1 transcription-repair coupling factor [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRGILHSWNELQHALRSLRAARFPYRVEGCTGGLRSYFFGEYVRTCCAHIVLVVPTEQDVAAVCTDLAHAAVPTRVLPWW
GSLPYRPVSPNAHVFSHRVEALCALAQRDATAPCAFVLTLRALLTPVPPLDYVRTLKRSFRVGEHIEIHTLAAQLMQWGY
ARVDHVSACAEFSLRGEILDIAAAAQAADNTQAYRIVCDFNTIERIHILAVSTCAVLQEVSACTLYAAKEILWSEERIAF
LHQNLQKLSECPAHCVPCIEELTHRKTYEGEEMFYPLCFERPTCVLEYFRHSPSPPSVFYLDYERQHNGARALQDECRNL
YHKMQLAHEHVPARWYPQPEHIVLDFSAVCALHLHTVYFTHFFPQLPACESICLASDPARSFFGNIPYFKEELLRLSKDG
WHVFVFAESEQQALRIRALVKGCDVTVLPCALSAGFSIPALKILIVQEGEIFGRRRKTPQSVQRARSTPIDTFVELNPGD
YVVHAQYGIGLFKGIERIKTAQSERDYVNLLYAQEETILIPIEQAHLVQRYIGNEGNKPHLDSLGSKSWETRKARVKKSV
ENIAQKLVELYSLRKTTRGHAFPKDDEWQYAFEAAFPYEETDDQRICIEEVKQDMQEAVPMDRLVCGDVGYGKTEIAMRA
AFKAVMGGKQVVFLTPTTLLVEQHFRTICNRFKHFPVRIEKLSRFVPKSEQKDILAKLAHGDIDLIVGTHRLIQKDVSFK
DLGLMILDEEQRFGVQDKEKLKQMKTNVDCLSLSATPIPRTLHMGMLKIRDMSLLTTPPEGRLPIETVIQQFDPNLVATA
IRKELDREGQIFYLHNRIENLESVKCMLQKLVPELSICVAHSLMGSEELEDIFERFYQKTFQLLLSTTIIENGIDVPNAN
TIIIDRADMYGVSQLYQLRGRVGRSDKKAYAYLLYYHDVALSDLAIKRLQVISDFTDLGAGFKVALKDMEIRGVGNLLGK
EQSGDIYSVGFDLYVQLLEEAIERLQHAPNEQRIETVIDLNYRGFIPHMYIAADEIKMELYKKIAAAHTHEELERIRTET
ITRFGPIPEEAAGLFTVAEIKVRCEKLAILSLKETHESLLIEFDKVCDTAFKKILRLVQTSNDRVRLDAKQPNMLILTSD
AIEIKEKGIFICEILKRLES
>SEQF2545_AGK83984.1 hypothetical protein TPFB_0344a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLLPVLLPCPLLLHPSRSGTSTRHSAPLHSAVCQHALKKCTLVPRSLCVAYSILGMSSSMRCARCVPHAFPTALKGAPVD
CGPTFLANTCARVAHT
>SEQF2545_AGK83985.1 phospho-N-acetylmuramoyl-pentapeptide- transferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGLIFFRYDRCYMLSVLSYLHVYFGPFRLLQSYAVLMGIALYAGFFFTYGVLPSAYRFLPQDRGRAFAPCAQEAAGKPTG
AGVIFVSVFVLLVYLLMRPSFVHALILLLTWGVMLTGYLDDCAQVCWGEYRKGALDFLFAVLTAALLGHFYFHDQVFWWF
PFFSDPVFVSPFLFFAGSVVILWMSINATNCTDGVDGLSGALVLMALLSMGTIFYFLLGNVRAAQYLLVPFVVDGAQWAL
MSFALAGALMGYVWRNAHPSTVLMGDAGSRALGFFIGVLVLISGNPFLLLMTSGVILVNGGTGLLKVVLLRFFHVRILSR
VRFPLHDHMRENWHWSTAQVLLRFMILQGLLTIGLLGVLFKLR
>SEQF2545_AGK83986.1 hypothetical protein TPFB_0345a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MALVYGAGIAEVYDFTGTAHDWSFGGFVQTAVEGGHPLRGTPGRARATVRSIRRLDVRLFLLPACP
>SEQF2545_AGK83987.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCMVPVRRFMAVCAVAACAGPCFCVQAFISSRIGYGHFGIYGNEIKDSYYKHVPMTGLGVDVVTSSGVAMVFNVETALTQ
LMFRAQALLGYAFEVGRFRFTPAIGGSFLASHDHAAGVALSLDFQYFFNDWVGLDLNIGAGVDVPVNSNLRYLVRVGTPE
LAKILITHIVTHGLANRWISGPRWWNSLSSWVGNAAGKVAGFVARLIANYLLKGSEYSMLVPVVVRLGAVYKV
>SEQF2545_AGK83988.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNGKRVFLGIVVVVCAARCFCADVFFSSHLGYGRFYAVGKDIEGQHMHVPSIGGGVCVVADSGFAFACTVDAALTRIMLK
TQALFGYAFRWGAFSLIPLLGMDVIVSSDHAFGVAAQVSFQHLISEWWGFALSVSGGVDFPLNPNTRFLAGKLPAETVQR
VALVALRQKLISEGIIKALDLGWFITFALTVVAEGFSWIVSQSAWIAQKAVNYFLSDTTRCLILPVTLRAGPTFRI
>SEQF2545_AGK83989.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRLVRSRLPLDVRDELVSLLGGMCFFLSTVEHVIPKPLPFFRVGLANLPLLISPDLLPFCAYARLVFLKVIGQALVSGTL
FSYVFVLSLAGSTASGALMYALRFVPCRYLSCVGISVMGAFCSNVIQLTLARVLVFGAGVWYVLPLFCALGAVSSTLLGA
LTGHFLSHSQWYAHLQNAACGQQDTAPPASLFFPVQAGCECTAPCSEHGLRPRVLRYVRMGTGLLLLLILLCVPRLSVQA
SVCGIALLLYAATGGRIRWMTLAGLWVGTLACYLRPPVGRVWATVLGVPLTSGALSAGARQACMASGMVYLSKWILRVPP
HLPGKFGQTVVHALSLMHRLSSFKLRGARRNATQEIDRILLALWATRQRTPTRR
>SEQF2545_AGK83990.1 peptidylprolyl isomerase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKIANECVVNIEYTLRDDTGEIIDSSDVMGALEYVQGHGMIIPGLETALINREEGEEFSVTIPPVGAYGEVQEDLRMTVG
RDQFPPNVPIEVGMRFDAGSGGDSRPVTVTDVQGETIIVDGNHPLAGKTLHFEVAVRSVREATDDDLAALLFRESTSGGG
CGSGAGGCGSCGAGCH
>SEQF2545_AGK83991.1 hypothetical protein TPFB_0349a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLTARAVSVPCALDRIAVIGDKPGEVLGACGPLLASCAVLCGKRGGVAFE
>SEQF2545_AGK83992.1 glutamate-5-semialdehyde dehydrogenase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVEVYARLRAAVARLAVCSAAEKDGALRAVRDALHAQREDILRANAQDLARAREAGLAAPLVARLALSEHLLEDMLRSLT
VLSLQRDPIGEIIEGYTLANGLEIRKVRVPLGVVAVIYESRPNVTVDAFALAYKSGNAVLLRAGSAASYSNAALLRAIHV
GLKKAHGVVDAVAVPPVLEEKYGDVDHILRARGFIDAVFPRGGAALIRRVVEGAHVPVIETGCGVCHLYVDESANIDVAL
QIAENAKLQKPAACNSVETLLVHCAVARPFLHRVQEIFATCEETTRKPGGVDFFCDAESFSLLTERGARKNVFHAQAETW
DREYLDYQVSVRVVPNLEEALRHIARHSTKHSEVIVTRDRARARRFHQEVDAACVYVNASSRFTDGGQFGMGAEIGVSTQ
KLHARGPMGLCALTTSKYLIDGEGQVRP
>SEQF2545_AGK83993.1 glutamate 5-kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRALFAAAKKIVIKIGSNTLAQADGTPDEEFLAECARACAALMRDGKQIVVVSSGAQVAGISALHCLSSPPQGAGLERH
ESRGVIPGDGASCKQALCAVGQAELISRWRSAFAAHQQCVGQFLCTKEDFTDSDRAAQVRYTLSFLLERRVVPILNENDA
LCCSDVPSVPADRRVSLSPQKRIGDNDSLSAFVALLWQADLLLLLSDIDGVYDKDPKAHTDAQHVPLVTDVSALVGKTSM
GSSNVFGTGGIATKLDAARLVTRAGIPLVLANGRHPDPILSLMRGDARGTLFVPVS
>SEQF2545_AGK83994.1 hypothetical protein TPFB_0352 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MREKEGGVVNDDFHYEVTRNWGTLSTSGNGWSLELKSISWNGRPEKYDIRAWSPDKSKMGKGVTLTRAEIVALRDLLNSM
SLDPY
>SEQF2545_AGK83995.1 ribonuclease H [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNAHAALTLYTDGACLGNPGPGGWAFALVPSDVPFLETGQTAPEAAAFTRSGSAYPSTNNRMELCAVINALQEAHGRAAE
AVVVVTDSQYVRKGITQWIHTWKHNGWKTAAKQPVKNKDLWEALSALADALSVEWRWVKGHAGDPYNELCDRLATDAARR
AAQSTADCP
>SEQF2545_AGK83996.1 hypothetical protein TPFB_0353a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAFERTQLCTRACAINTFEYNKVMQNIHLCPLRVSFPLKTVQHVHPRRKCNAHVYTALQNKTAYRKNQTVVPRTKVPAQS
VRASFSLLAKISSLHHQLSDQYIVPTAQNCYRRRDYERARCTYPVH
>SEQF2545_AGK83997.1 dTMP kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNILHNFVVFEGIDGTGTSTQLRALERHFQARKDMVFTQEPTGGEIGTLIRDVLQKRVIMSSKALGLLFAADRHEHLEGA
GGINDCLAEGKIVLCDRYVFSSLVYQGMAVSGSFAYELNKEFPLPEVVFYFDAPIEVCVERITARGLQTELYEYTSFQEK
ARKGYETIFRKCRHLYPAMKVIEIDAREEIEVVHERILHHLREYRRLK
>SEQF2545_AGK83998.1 hypothetical protein TPFB_0355 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQGSVQIQKGNISSSYTPEKHPSHPTSANGSMSPKRICELRKEDPSSLHKQLLKNSLEKGTEHCDRTTKTYGQIFQLFCL
CCAGAAPFYRARAFRLQSTFLIYTLHCSSDSVSTSTHYFRRLYSRRW
>SEQF2545_AGK83999.1 putative RNA-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSAKIYVGNLNYATTEAGLASLFSQFGEVLSVAVIKDKLTQRSKGFGFVEMESAESAELVINELNEKEFEGRRLRVNYAE
EKPRFPFKN
>SEQF2545_AGK84000.1 biotin--[acetyl-CoA-carboxylase] ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDEAASRAQGCEEGAVFCAGEQVAGRGRGDQRKWQSEPGKNLLCTVVLRRVAFPAFSLCVGYAVALAYMAFLGGVCAPRI
KWPNDVLVCDRKIAGVLCQVRAGALLVGIGCNLLQVKFPPELSHACSLAQIVGGERCPDPFAFLPVLLDRLYACVMAPPS
IGVLESCLWKQGEYVCFRECAGTRPPILGRVVGLAADGALCIDSAGSMRSYYSGEIAFW
>SEQF2545_AGK84001.1 glycosyl hydrolase domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPVHSLAFVLDCNLPFVRGAGASSLLAESRFFLEISYTYLPLLRLCETLERERVPFNISLAIGPVLCEMLANRVLMDRYR
RALDALIEFGEREAIRLRNSLQERVQAEAVLRSLRSHRDYFDHCDGALLERINHFFRTGSIELLATTAVNCFLPFYQDMP
ESISAQIEMGLINYRKHFSSIPRGFYLPELGYAPALERTIKSYGFSYTILETHSFLFGTRVPRRGIFEPAQTSNGLWCLG
KDRVATAEVHGATHSFCTQAVYGNTEQDAGFILPEEALYPLFEPHKERMATGYLYQARSGTPYEQEKAQRTCVADARAFV
RNRTEIFEKVVHATAPFEAMSVCVFPASLFGVAWAEGMDWLEAVFRTVAESAQMRVSCTAALTCPAVGVSIIEPFFGSSL
GGGYADELINSANDWMHPAIQKTTERMIDLTERFAHDTGFRERLLNMAARDVLLCQSLFWPLLGNHCRYPEYAASECADH
LKAFTRVYEALGSGEVSAQWLMRRERELPLFSEINFRFFSKKK
>SEQF2545_AGK84002.1 hypothetical protein TPFB_0359 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MALTKSFLESRSTGELFALADELGLCLPEDLNRRLVIGEILDCYHSALDLNPPCAPQSLESKGTSCAYNTTEIHILARDP
LWFFVFWDIHEQLFCTLTQSPQFRSFFLRVHSLGGHGWHTSLDHFDIDVPLKDRKRYVHLSLADDANRIDLCCKMLQRER
ILAQSRVVTLQRSVIERSLNPEDPTGAEVLSLCGLPLLEETYPSTSLPVCS
>SEQF2545_AGK84003.1 hypothetical protein TPFB_0359a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFFTFPLSTIDFSTTSPPHGQLKRCVAAAVREFLLAPAIFIPPSSSLARLHHIVLLVKRMANSRGKTRHSPRLPAVRTLC
IAI
>SEQF2545_AGK84004.1 hypothetical protein TPFB_0360 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAGASKNSRTAAATQRFNCPCGGEVVLKSIVDNGKVKNIAECPKCRRVERRPRDFN
>SEQF2545_AGK84005.1 acyltransferase family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCGILSIVVSIAVLAPLAVANTLCYALYRPGCRWVNHAVSTWGARTIFAVLHTYGRLKFYSDYTHAEHLPTQYLVVSNHQ
SVLDTPALMRYFGYIDAPRLRFVAKRELARFVPLVSTMLKSGRHCLVDRHQSGAQAMQALETFTHHVMRERWLPVIFPEG
TRSRNGALRIFHAAGFRALTARLPLPVVVCALDGGWNLRPLLKIGQKLKGSAYRVKVLGVYPAPHNKDEQLSLLREAKAL
IQAQLDVWRSETTCPQDECLTRASKDS
>SEQF2545_AGK84006.1 hypothetical protein TPFB_0361a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQWCIDLLTAHPLIVPFPHSPHLLAIVHVSAADDKEKVRQSKGAHARFMA
>SEQF2545_AGK84007.1 ribosomal protein L28 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARRCGLCGKGTISGCAVSKSMHHCKRVWKPNLLAVRVVVDGSALNMRICARCLRSNPLMKKAQPRANAPLRAAAPKL
>SEQF2545_AGK84008.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARAQVRLSGRFLALGGYSLYAAGLVLLLYRAVGVYVWIHFYQNQTLSQLSTHARSSWVSIGGHASLFLGAVLLTVRDVR
TFRDDSTMWIAPVVLWSAATYSSMGACGFSLRAVASGACGVLLFAVWSLASELGRRRP
>SEQF2545_AGK84009.1 sensor histidine kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPMSDYLDAGNEELLKDFFSEAEQQVEQLESNILVIEQDPTNRDAVDEIFRAAHTLKGGAATVEMHELSGFTHAVEDLLD
GIRSEKVTVDGAVVDLLLTSLDVIKAMLESRAGGGPYAEDVSDLVARLRSYLPASGTVPGAARGLSVSSPNAAEAAKGTA
VGEDGTEAPQVGRVPPLSLLSEYDRLELREIVPPEHSVYALTVRFDESNLMNTVGGIQVFTALKSCASVLKTVPDFDALY
QDMFHEYVVYFVSTVQDSVCVSQVASIPDVTLSVSVAEVALADLCTPLSEHGELGVCADAGTGGVSEGSGAAVRSGGERV
PNSLPKQVAGCAVPSAKDSSKATSSGYGSGSVLRVDAKRIDYLLNLVSETVIIKASLNQSALEFGEVYTLFQNANGAYKE
RLRKFFDRVPAYLEKVKNGQDADAVRKGMIAEAVGVFDIFSSFENGLKQSVTKFRSSAQNLGRISGELQEGVMKIRMVPI
SQIFSRYPRVVRDLSRDLRKEVRLVIEGEETELDKSVVEDLLDPIMHCVRNSLDHGIEAPEVRARSGKPAQGTLLLRASN
EGNMIVIEVADDGRGIDVEAVKTKAVERGVLHPGKNLTEVEAFQLIFAPGFSTSRSVSNVSGRGVGLDVVKTHIERLNGT
VSVFSEVQKGTRFVIKLPLTLAIIQGLLIRVGQEVYSIPIASVIESHRIKSEEINRIDNYEVFNVRNEVISLLRLDRLFG
ISCDDEVTGQYHYVVIVGAAEKKVGLMVDALIGEEDVVIKPLRDQFTSSPGIAGASILGDGSVSLIIDVGQLLELGLKRE
ILARERREATVW
>SEQF2545_AGK84010.1 chemotaxis protein CheW [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVGDLGHGLGTMIEHMEAEIGIRESFDGGVREPLAVIDFKMVTFSLAGKDYAVDIMQVKEIAKAGSFTYVPNTSPFVLGV
YNLRGDIIPIIDLRRFFNIPAPRKSRQAIENMVIVTVEDQTFGVVVDGIDKVIGVSKTTIQPPHPIFGDINIKYIRGVVE
EAGKLYILLDVHRIFSFRLGEEERTAVVDRGVVPSPPPPAVSVPPGDEENLNVGFISDTLAAFGRFFTSAVNEGWLRSRY
LVWRDVRSGAEVQLQHEEDVAEFLSTFPSPDTGVFWSGEYAASVGSVLSRMQVGKVVTVWNIGCGAGHESYSLAVLLRKT
FPDAVVRVHASDSDLFSISNAPMLTVPEHVIGDWYKPYVVKGVSGSYTFSQEIKEMVLFEYHDCTHPSALPDVDLIVARD
VLSSLAVPVQHTLLKEFSEKLKATGVVLLGQNEVMPKDTGWLRQIEGTVAVFSKE
>SEQF2545_AGK84011.1 putative chemotaxis protein CheX [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRVEYINPFSEAAYVVLSEVLAGETKRGDLYLKSTCMPVMGVAAIVGLAGDVEGRVVFDMTLDTALKIASSMNEEKLAAF
DELARATITELANLITAKAVTTLHELGFKFDLTPPALFTGDNMEISSSDIEALIVPMETPQGKVEINVAIRDKV
>SEQF2545_AGK84012.1 response regulator [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MISKQDFPTINDRVPAGQKPNGAPYRVLVVDDSMFVSKQIGQILTSEGYEVADTAVDGVDGVEKYKAMSPGVDLVTMDIT
MPKMDGITALEKILEFDKNAKVVIISALGKEELVKKALLLGAKNYIVKPLDRKKVLERIASVLK
>SEQF2545_AGK84013.1 hypothetical protein TPFB_0366a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRTIQRVHLFKIEPNPFQPNQLGTTKEYRNYTAGKAPQGPEQRAEGDTTSPLAAHTQKPRTQRDGHSAREGKNLKKPSTH
ASGQTVRDSPQDTSALTLVRLQFAPTPFSYRAA
>SEQF2545_AGK84014.1 chromosome segregation ATPase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLFLKTLEVFGFKSFADRVRVEFADGVTALLGPNGCGKSNVVDAIKWVLGEQSSRALRADRMEDVIFNGTESRRSLNVAE
ASLTVCDEAGILSLDVPEILIKRRLYRSGESEYFLNGNAVRLKEIRELFWDTGIGKVAYSVMEQGKIDQILSNKPEERRY
LFEEAAGVTRFKVRGAEAARKLEKTAENLRHLEVILQEVEKSYESSKLQAAQTQRYRMLKEEIFARDRDLGLLRLRGFLE
NQARADGALQRNRARRDALQTQVEEAQQTLSARIGEINDMEKRVDALQKEIYGLAIEQKAKQNEASLHRKHLSELKESIG
QIEMRKIGVESRVQNLEEEVAEQDAHVYQLGSALSSVEEHIESFARSLHVASEHVSENDQTLRDIQGQMQEISAACVELE
ASLRDVAEDIAAELDTRLSAAGYSARNRAEAERTLVAGVQRLRTFVEGRARIVSDFLVVDTHTEGELCRMLTTVVDAFNE
AVKIVHCVESDIAEYARVSARFIDEFVAPQGIMTKKREFERQLEQHRAQLERHAARQRTLQEENKLLVGKIEACRKTLES
LRVDQARLRAEAEAGQKQAAGTRGEVARQRAVIKELEGELFTEGERVAALEERLLEIEGEIGQLEQRGVLLTKSLENCEG
EIRVRNAAVTSEERALQEARVELAQVGRQLEQAHRELMQCETEIRNLREHFREQHTRDLSEFEDLIPGIEKTASDLRQER
GELQARVKEIGAVNFMAVEEFQEVKERYEFLVAQVADLEKARADLQRVTDKIKAESAELFLATYRRIRKNFHEVFRRLFG
GGRAEIRLSDPAAVLSCGIEILAQPPGKKLEHIGLLSGGEKAMTAVALLFATYMVKPAPFCLLDEIDAALDEHNVARFVG
MLDEFSDVSQYIVITHNRRTVLGARTMLGVTMEEPGVSKVVSIALESASERPANGEAGGAI
>SEQF2545_AGK84015.1 hypothetical protein TPFB_0368 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMRLRGVAGALLGAVVLVALGLMGVWWVFYPKKGDRGAAVAREPVLLHIDPAQMEAADEPLTLPPIERSRERMSAWSEQE
CLRQLEYPTEKAVQALEHANEKRIQQMLEAVP
>SEQF2545_AGK84016.1 hypothetical protein TPFB_0369 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSVWVALALLGMCVSCTHVPPPRALIVSKEPPPALDSAPRPAIPEAVPLPSPVEEEIAGRLPPAPAAAPERVPESSQERE
QKPESSKPQVVEPVSLASPVKPREAGSVPDVLPVPEVSSLHVAPPAPPAPTAPRPHRPSPPPVSPSASKPKQRAVPPSPP
PASEPPREAEVQAEPEPAEDSPRAMVPEEPPEDEVPRVSRAVQLAVGQKLEVLYPGEGWVYVGEHTAQPGLRYHQRKLEE
SHSLFTFSAEREGDFVLAFSYFDVFRDDFVSDALAVKVVPKREGLARVVRAPEYRRTVSSPPDTVVSELSPAGTGTERRA
EESGTSGSQRAAAHTGAPVRQDQTDTAVAEKAQHGTPRPDEKKDREPTVGGRDPVPSDAVAQGVSERYSPRKISPASQPS
APSAAPIEAHVPASAHKEGQEKRDHLAEARQFCAQGNARDALASLGDFFAQFPSHERMDEAWFLRGKAYEINGAQRNVRL
ALEAYKTILERFPHSPYWKKADERARFIKNFFIKIS
>SEQF2545_AGK84017.1 hypothetical protein TPFB_0370 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCAPLYDPPLAFTIPQAEVSHMNERNKLLARALYSCVPHVQGSDDYEDDFEDSDFQDGDFDDFEDEDGFDDDFEDDDFEY
EDEDNDLDFDE
>SEQF2545_AGK84018.1 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQSLSLRAHAKVNMHLWVGARRADGLHSIESVMQRITLADSLSLSRLDIPGRCEVCSPYMALPRENTLTRAYARFCQVTG
VHDGVRVRVVKRIPAGSGLGGGSADAAALLCGLDTLFGTTLSARVLREVAYSVGSDVPFFLASQAACVLGGGEQLVPLVP
KTGYLGLLVWPGLHSGSAQAYEDLDRLRACGVHAADGEQYSLRGATALSAHYAQDCARWRFFNSLDTPVQRRYPVVALAR
WDLARAGACFTAMSGSGSAVFGLYRDEEELRRAHKLLAKRWCWCVRVRLCG
>SEQF2545_AGK84019.1 ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDERRLKGKRRVQLGKYAAVRGRKEGRLPAVMYDHRGVSVPLELAQQDFDRLFRALTRSTVLSLELDGGEVFCVFVKDYQ
HNMVSDRVEHVDFYAVEESVPLRMRIRLQLCGSPEGVRYGARLEKGLSYIEVESLPRNLPDRVVLDISGLGAGDVRRVRD
VPLPASVVVLSDPDAVIVALSSSASEAGSPAGARTG
>SEQF2545_AGK84020.1 PP-loop family ATPase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSESRQKLHPLLVHVARSFGHFLVPRKPSCLLVAVSGGADSLALLYAAHELAPDFGVCACAVTVDHSLRAQEGALDARFV
RALCARFSPPLPCFVQQISAGAVHACAKIRGRGVQDAARALRYKVFDHVAARCGAQVVLTAHTRDDQYETLLMRLFQGAA
ASALQGIRAARGRYVRPLLKVSRTCVEDFLQTRGVRWREDASNTCRKYVRNRIRHELIPALDAVLAGWRSGLDKTFAGIS
AEHSFCVAALTRWREGCSHAWEPVPRALGTRLRMPRSDFLAAEFILRFFLLQEACVRLGVSHRVPRGALERCARFDGVRR
IHVSGLQLERAGAYVLFSCIHASDTARETKKQDAGSPPSSEKQGVSAIYVARPGAYPCACGTLLVEVRPAGVFVCCAQDH
VGVGPFSFPFYIRTHRTGDTISIRGGHKGIRKMFSEWHVPLSDRTVLPMIEQDGVLRALYGAALGYQNRYAERTPHE
>SEQF2545_AGK84021.1 hypothetical protein TPFB_0374 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRSMAQHLVTKIVTRRGLLMSKGMCPRMGRLCAVSIFCAFSGIQDASCVSEPAPPQDLERNHPGVAARYLQEGRWQEALS
QAEQGVASAPQIADFLFIAARASYALQQPSARALQWMARAVAKDMQWCVYDIEEVRLFYARLCVDTLQHARALELLATAE
QVSADADWLRARARYGLGQVEHAQELIEKALERWALDARFAKLFFAQERSRRPSSRSKKIADSILSRLSVWQEQDPSLLV
EAALFEPRTNMAFRYLQTYFTLRPLDAPGESSAQSSYEQSTRAGDSAPEQELYARAQSIVLGLQYGVLDEQRAMEMFCTL
NSPLAVPAVDPTDDVSSFGVHASSVSSSTPLQRVVVLYADLLHEFSRLLASRPIRARFARFLAEFEGVLYTDENRDGIVS
ARVFFKAGRPSRAQFDTNQDGILEYEVYANDGAPTCVHTMHSTQKTELSRASVFPIPQNIAAHDHERAAERWIAPRVSLP
ADNGVEGETQARVPLTQQGYRVCYDRYPEVHQVGWEDKTYVLRPRALRWQPVRMQSLDLARDLEGVRSHDFFTMVLTNEP
LPTEQQITVSSLYYEKPDSLFERARVRTYLDEGLPLFSETHVGSRFRARTHYVDGRATRRDSDRDDDGFFETREYYNAQG
AVRALSVDVHKDRSFAYQEEYGAKGQKVQKWYGRGRVTISHTELPTGHARTEWLHPVTGRHVTVDFVQGVPKRLLVDGEV
HALTKDPRNAALYWVRRIPRNGDEVGQRIVESFRAATSPVVSEYFRTGGSVVRAVRSGGVVFAEELEPGKE
>SEQF2545_AGK84022.1 hypothetical protein TPFB_0374a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGDPVFRACNEKRPYLAEKVDGIRFFLFTHERCRFSYSFYRLFYQVVEERTDALKVDMRGGLRSSAGEPAKRKLRNLQSS
NIKVYR
>SEQF2545_AGK84023.1 hypothetical protein TPFB_0374b [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQILQQVAQGIASHFGHDCEVAVYGVSSDGKNCAVDFITNGRVTSSRVGDRPRLSLFKNYGIETGKGGSTTSFARRTAAP
LSRACCIFVTNIARLRRF
>SEQF2545_AGK84024.1 hypothetical protein TPFB_0376 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLDSTLVPSYTGGGHGCSFVKTSLLLSVCAAAALSGCATGQSDAVTDPLSVLEVSQTETREALMLFVPYNETGASVTIFT
PELVARLSKSYRFLRVEAPHSAYTLSPEARERNRLLFSEYEVDGLPFLVLQSAQGDAYFAQRIHSTLSSEQELWALIRSA
DASRKKVLAARDRVAQTEAAEKAIAIDAFLKTVRYPRSARYDALRKEALQADHENVSGLHGDYMFHLARRRAEKFIKQEN
LVAAGNAYKDLAQSPFLSASQKQEAWYLTAYTYALSEKVSTEDVVACLRKAVAAHPHAARVAQIKQTIKKLLTERGI
>SEQF2545_AGK84025.1 flagellar basal body-associated protein FliL [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLCVLQCPMTEETAQRVIRALRTVAALIVCVLLLGTCGAFRVRTHSAPRETQTRRTTRGIAQRESAHAVYAELGRLRALS
ADKQPVSVIITPLLQYPAADHALYEELVQKKEQLRRASLAWCAQHTAQELHMLGPEQLKIALRDALNTQLSLGRVTHVFL
EEFIILF
>SEQF2545_AGK84026.1 Sec family Type I general secretory pathway protein SecA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLVRTALRLIFGSQHERDLKNLLPLLNAVNAQESWVLPLQESEFKQKTAEFKARAAAGEALDAFLPQAFALAREAARRVL
GERPYDVQILGSLVLHHGKIVEMKTGEGKTLMSVAAAYLNSLSGRGVHIVTVNDYLAERDARWMRPVYDYLGVSVGVILS
SMGSQERRCAYACDITYGTNNELGFDYLRDNMQFLTEEKTQRDFYFAIIDEIDSILIDEARTPLIISGPAENDTQHYAEV
DRLVGQLQEVERNPATGDYPNEVDGEEVRGDYIVDEKNRKVSFSGPGMLHIQDVLTHAGLIQGSLFDGENFKYIHYFTQA
LRAHLLYRADVDYVVKDGQVQIVDEFTGRILEGRRYSDGLHQAIEAKEHIRIAQRNRTMATITFQNFFRMYKKLSGMTGT
ADTEALELNKIYKLEVVVLPTNLPVARVDEHDVVYLSEEEKWSAICDEIKEAHTRGQPVLVGTISIEKSEKLSALLRTRG
VKHEVLNAKNHAREALIIAEAGAKGSVTIATNMAGRGTDIKLGGNPEFRARQSATAIASKHGSSSVTVQEHMQACYEAEY
TRWRADYEEVKQLGGLYVIGTERHESRRIDNQLRGRSGRQGDPGRSKFFLSLDDDLMRIFGGERLKRFMSRVGMEPGEPI
THSWLNKSIERAQTKVEARNFDVRKHLLEYDDVLNEQRSFIYAQRAQILIDEHVVERVYTTIEEYLNREITALRQELKRR
GRLSLGAFQQNLSTLFDYALGGEDASGWNETRLGTLKQEILAHLKKNIESKYLLAGAQNMDTFIRYQYVQAIDKKWLDHL
ELLESLRESVYLRSYGQKNPLTEYKLEGFDLFYTMLDDIRLSIASQVVRVTVHMEEQRVPRPPHVAQAAHEFQALGQPGR
GHGSLSALPIQAGAKVGRNTPCPCGSSKKYKHCCGR
>SEQF2545_AGK84027.1 putative DNA repair helicase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTSVPKPLIIQADRSILLDVHAPEAVAARKALVSFAELEKSPEHLHSYRLTPLSLWNAASAGFSPQMIAQTLTRFSRFTP
PQTVLDWVVDIMSRYGKIRLREDTTHSTLLRLQVRDAHIAREIAASKSLASHLSPTTACLQDGPLPTPDTARIAQPDTTP
QVQGAQTGCSYDFLLPRLHRGTVKQLLLRHGWPVHDEVPLREGTPLSLRLRISPASCPPPSTAYPCCHTPGTPSFVPRDY
QWEAADAFVGNRTQGSGFGVVVLPCGAGKTVVGLLVMGLLQTDTLILTPNSAAAQQWKRELCEKTDLDGTSIGIYSGECK
EIRPVTIATYQILTWRAHADAPFSHFRLFMERSWGLIIYDEVHLLPAPLFRITAELQVVRRLGLTATLVREDGCAQDVFS
LVGPKRYDVPWKDLEARGWIARVRCVEVRVTMDRSLQYQYMTAPVRLRHRLASENEAKVAVVQRLLRAHAGAPTLIIGQY
VQQLLHLAHVLQVPLVSGRQTYAAREAIYQRFREGTLQVLVVSKVANCALDLPDASVAIQVSGTFGSRQEEAQRLGRLLR
PKICDAHFYSLVTEQTVEEDCALRRQRFLVEQGYTYETLRVSEVHE
>SEQF2545_AGK84028.1 conserved hypothetical inner membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLGAELADTGLFVRFGALHFAIASVAVLLSALFVLLPFALPRLLAHKNLARAGVAILFLRLGLMLCGTLLDGRSWRNELP
FHLCPAALISGSLYFITRRPIFFNLLYFWHFGSFVAVLYPDLTRAHTILYAYLFMLTHCLEPAMVVFSLLHLRERISKRG
LQCAVLGFLLLAANALFWNRRLGANYLFISKYPLEILRVIRPFFVYQLLFVSALCLLMLVLYLPFRPSQHGRNQLFVI
>SEQF2545_AGK84029.1 MraZ domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEDSAFTGAYSYNLDEKGRLMLPARLRVALSDTRLVLTCAIESCLWVFPRAQWDRFSSQISARASLFHAPSRAVLRRLIA
PAQEVELDRAWRLFIPPSLREYAALEKDCLILGLSHCLEIWDRARYRAYLAESEADFRAGTETLQDLCL
>SEQF2545_AGK84030.1 S-adenosyl-methyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSLSGHTHTKEEVQAEVEAGEVQCPALCHQPVLVQECLTLLEPAIVGISQGADSTRDGAGAFFIDGTLGDGGHTQAFLHA
YPALRALGVEIDPSMLARARARLTPFGKRLRYVLGWSDVFFASAYASAPASPATGRTAAGAAGVPGAYPAPQAVLLDLGI
SFFHYRGAMRGFSFAEEHMLDMRLDPQASQTAADLLNRLPQARLAQLFFEGGEERYARRIAQAVCAQRRQAPFCSARAFA
EVVARVVPPMRTARFGKRRGVLGVLPKLHPATKAFQALRIAVNRELERLPRLLTAAFTALAPGGRLAVISFHSREDRIVK
VHFRHWAKRCSCPARVPICSCGGVARASLITKKPLVPSCVERAANAASRSATLRVIEKR
>SEQF2545_AGK84031.1 hypothetical protein TPFB_0385 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MREKGAMREKQRRGIPRRQRGMTVQKVSALFFTVSIPVLLCAGVWQASRYQAVERVVREYDAEQHRIIAENKRKISGIAI
LSKPDRIEKLAVEKLHLHRASHAEIVRIKLRPAHKDSSPHASEF
>SEQF2545_AGK84032.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLLSFDEVCAAVQGARVCDARGARGFDGVSFDSRAVVPRDLFIPLRGAHVDGHTFVEEALQKGAVATLIDQRYPHAGEYV
AWCTRFGAACIAVHDTLRALQDLASFYCKKFPALIRIGITGSSGKTTVKEMARAVFSERYRVVATPGNLNSEIGLPQSLF
FVRAEHEVGIFELGMNRRGEMRTLAQILVPHYAIITNVGCAHVGILGTQQAIAEEKKEIFSQFTEHSVGFVPDDAYRVFL
SNIPYGRVVVYDQGGRGLATEVIDEGLRGSRVLYQGRWIRVPLPGVHNAKNALAVIALAAQVGLPAEEIQRGMERVKPPF
GRSHVVCASLTFLLDCYNANPDSMAAALHLCAHISAVSKVYVLGDMGELGVTAAEAHYRVCVLAAASDARAVYVFGPEFC
RAVRKVSWGRKRVYAFALEELSALQETLDAQLRRGDFVLVKGSRSVALERLEPLLRKER
>SEQF2545_AGK84033.1 cell division protein FtsW [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRPMISIEKNVHQERYSFVFILLVALMVGVGFVTLYSGSVHYAQRFFRYPGYFLVRQGVSIGIGLVCLLFFTFVRLASLR
KALSPLILVAFALCVCTFFPGIGSTRNGATRWIKVFDINFQPSEFVKLVLIVFLANFFDKHREHFDTPIRSIFPPFVVSV
IFVSVVFFQNDFSTAMFLLFITVVMFFIAGAPLWWFLRGIVVLAPIAVLMIVTSTNRLRRVLSFLYPDRDPLGAGYQVNA
ALEALMDGGLWGRGIGNGVRKIASVPEVYSDFIFVVIGEEMGFIGVCLYLMLLFAFTLTGISIALRCANRFNTFLAFGAS
AAIVLQSILNVAVVVRLVPATGIPLPFFSSGGSSIVVTLSLCGLIINVSGDEKIRREREETVFV
>SEQF2545_AGK84034.1 cell division protein FtsQ [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKQFLCRNTEACKYPLVGYMSMRVRVAVLKVVIVILLLVLCVEFVFYLFVVPATSFAKVEFSGNVTISPEYLMKAAGLT
GKEKWMSLDGFTISERLASVPLLAQVEVLKKFPDTMHVHVVERVAIALGFVHVQGRAMPVQIDKTGTVFSVGTAPLDTVL
PVVSGLEFRNPRVGLRVHDQLVPLFVQLDNLSKRNPLLLGEISEISIEQKRHGGYDLALYLVRAPIRVRMDKNLSEEKLR
YVILLVDALREWQTQRRIKELDVRGGTAVYR
>SEQF2545_AGK84035.1 cell division protein FtsA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGEVIVGLDIGTESIRAVVAERLEGGALQVVGVGVGHSKGLRRGVVVNIENTVVGIHHAVEAAEMMSGIEIAHCVVGLGG
THIEGRNLKGVVAVADKGKGHREVDQSDIDRVLEVACAVSLPPDRKILHVIPKVYSVDDQHGITDPRNIIGVRLEGEVHM
ITGSATCMRSVIDCVKRANLHIDFLMHNGLAAVRSVLNDDERNVGCVLINIGGGTTDVIAMYKGSPVLITSIPVGGSQVT
SDLAKVKNLPLETAERIKIKDGCCWIPLLEGEGSVLISSQGNRIPVEISKREIAEIIEARMCEVFTIVRDRLSTVETQSG
RGIIENIILCGGGAQLTGAVELASAIFDTPRVHLGIPGTLGGLAGEYRSPEFAVVLGLILEYTHKQGQRAYQGRAEMERA
GVFTKVKDIWRNLF
>SEQF2545_AGK84036.1 cell division protein FtsZ [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMNIELAPSGEEFTLSPTVIKVIGAGGGGSNAVNRMMSCGLQCVEFIAANTDVQALSYSTAPKKLAIGTKVTRGLGAGGD
PEIGEKAAMEDAEAIASALQGANMVFITAGMGGGTGTGAAPVIAKIARELGALTVAVVTKPFRFEGRAKMMLAERGIEKL
RTHSDTVIVIPNQNLLSVVDKRCPIKETYLVADDLLRKSVQSISDLITLPGEVNLDFMDVKNTMEGQGYALIGVGEGEGE
NRAVDAATAAINNPLLEETRIEGATRLLVAVRGSENLSMGEVDGVMSVVAKTIDPDAIIIHGTSIDASMQDRVRVTVIAT
GVPQASISIAGDTHSSQKIKTSSYGAVSTGVYISSDEWNRAKSSKQPNLPGLATRNSAVQETRMEKNGVKGHTFGVPLPS
VNEDLDEPTFLRNRNKGL
>SEQF2545_AGK84037.1 integrase/recombinase XerD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKDVDIRVQSFYAYLISAEAHALLTARTYVTTLMLFQKNLDPPCNIESANAHDCVRFIEKRSAAGVSGKTIAKDMAALHA
FYQFLILEQVRPDNPMQDVDAPRRAYSLPRVLSPEQVNTFLQSIPLCTPGGVRDRALFELIYAAGLRVSEAVSLSLSDIF
FAERLLKVTGKGNKERMAPFGEQACYFLMQYIREARVRFTSAKHPENSEKKGAVFLNRQGGRLSRKGIWKRLQDIEIRSG
VETHVHTFRHSYATHLLAGGVDLHSVQCLLGHADIATTQVYTHVENGQLEACHRACFSSEGLRDEN
>SEQF2545_AGK84038.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDSSKRVTARVFLQKVFVMKTRRCASYVGGALCAAFFFFHSCKERRTVQRVQDLEKGVPHPTSIEELRRAVKLHEQRLER
LHAVQDQVGVWYKMLALRYFDRKMYTHALDAFTQAITFAPENKHLFFYQALCAAYAAKYVAPIDPEKKMQQQAAYRALAV
SAYVRALSLDAQYSHALYGLSVLYVFELNQPQNAVPHLQKLLELKENTEAALFVLARAYYTLGRYAQAIECYDRILVQSS
DSHQRDRARQNKELVTNVSQRATRGDRG
>SEQF2545_AGK84039.1 SMF family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNTDTVLTETHKIALALSYCHFLKGGERLRVSKAVGSFQELTAWKVRDFERVVERHIRTAGAQLSALPHLVRHGIQTMRC
YQIKMVFKDDDAFPSWLREISDVPFVLFYRGTLPCATQPIVGMVGTRTPTGEGVRNSLAFSKACAESGIAIVSGLARGID
GFCHKGALAGGGYTLAVLACGVDQLYPRSNSALAARIIETGGCILSEYAPSEHVMRYRFPERNRLISGLARSLVVMEAPK
KSGALITALCALEQGRDVYVYEPLLESLQNEGGRLLHAEGARALTCVQDMFDDWEYACTGRT
>SEQF2545_AGK84040.1 DNA topoisomerase TopA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEVRGLQPKRQKTFARKHLVIVESPAKAQTIEKYLGTQYVVRASMGHVIDLPKSRLAIDIEHDFQPEYITVRGRAQCLKE
LRTLSKQSLQVFLASDRDREGEAIAYHLAQSIQAYCDTPIKRIVFNEITPHAIRAAIGHPVPIDTAKVNAQKARRVLDRL
VGYHLCPLLWHKVKNGLSAGRVQSVALRLICEREVEVKRFVPEEYWTVEGTFEKDKKSFSALLILIQGKKAVFKSKQEAT
SSIGLFSQSEARVSQIRSFEKNVRPKQPFTTSTLQQCAANRLGFTSRKTMQVAQQLYEGVSLGTHRVGLITYMRTDSVRV
SEAAVKEVRAWIATHFSDALPGTPNRYAAKGKSQDAHEAIRPTYVAHTPERIKAHLTRDQIRLYTLIWERFVASQMTDAR
VRSLTFEITAGPAVFSATETQVIEQGFYRVLKMLSPKDLSKAVLPPTKEGEVVALHNVQSVQHFTQGPVRYTDASIVKML
EEKGIGRPSTYAPTISVLLDRYYVTRIQKQLMPTPLGKVISDLLTTYFHDVVDVSFTARMESKLDEVEEDKIKWNCVIAD
FYPAFSEKVSTVMKDLNSMRGVFDEKTDVVCSQCGDTMVKKLGRFGFFLACGKFPECRNTQPVPLAKCPRPACDGNIVGK
KTRGRKEFYGCTRFPVCDFVTHFKPTSAVCPQCRCFLVEKSNRRVGTYTACVNPECRYVSPTRKNLSLGKEAVLDGSHRG
AQDKGAVQHYE
>SEQF2545_AGK84041.1 integrase/recombinase XerD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSNEQFTQYLEYLFRVRRLSAHTVSAYARDLNLFERWLQHAQRACARVTVSDMRLFVCELGRRGLSAASINRVLSVVRGF
YVFAKKKHWCADNPARLVKNIKGPSKLPRFMFPPQAKAFYTLPSRTDILWQERDAALFAMLYSTGCRVSEIAALSLKDVH
PHLSSAIVRGKGDRERTVFIAPFAQNFLHVYMQARAQRCARYASCTPALFVNQRGRSLSVRGIQYLVSRYVLLAQDVHAL
SPHAFRHSFASTLIRRGADVRVAQELLGHASVSTTQRYVHVTSEQLQDLYHRAHPRG
>SEQF2545_AGK84042.1 flagellar basal-body rod protein FlgB [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNSFTRTVDLLHRALDVNALRYEVTANNLANAEVPGFKRTDVNFEAELKRALDSQRNETSFFKQATAGTNMLSSDVIDYR
SVRPRRVLDYLTDVKANGNNVDAEQEAMHVLKIQMHYQMLSQMVGFQYRQVESVLR
>SEQF2545_AGK84043.1 flagellar basal-body rod protein FlgC [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGLFSGINIAATGMSAQRLRADVISDNIANASSTRTQEGGVFRRSRVVLAQKNPGIDWRIPFVPEQLDRGVGTGVRVVSI
EKDNAPSRLVYDPTHPDAILSGPKAGYVEYPNVDIVTEMVDLISASRAYEANISVISGSKEMFQRALEIAR
>SEQF2545_AGK84044.1 flagellar hook-basal body protein FliE [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTPVGTITNSANVYKVPSLRKVPEIGPVSVESVRQRMRGNTDAVDQAVNKKAMSFEQTLLRAFDQVNQKQQKTAELTEQM
IVDPESVDVHDVTVAMAEASMSLKIAQTVIDKVLKSWNDVTTAR
>SEQF2545_AGK84045.1 IIISP family Type III (virulence-related) secretory pathway protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGEWLGQLGVKLKTQWKKWTLVQKSVLAGAALVSVMGVVVLLTWSAKPTLVPLIDTPITDETVREKIILRLNEENVRATV
SSVGLISVSDEKTARRMRSILIREDLIPKNVDPWAIFDVERWTRTDFERRVDVRRAINNTVTNHIKALDDIDDAHVVINV
PEDALFQADQKPITASVVIFPKPSSTIASERKKIEGIQKLLKLAVPGLKDENITIVDSDATVLNDFEGFKDADRLSLIEK
QQKMIAKLESQYEAKVLALLQKTYGKDRVRDLNIKIEMDLSEKTSQTTKYLPIEIRQDNPDTPWDDSQVVPSVTSISETA
TTTWQGTGLNPEGPPGVEGQTPPAYKDMSNQVGLSNQSVVKKQEAISKSEINEVVSPVLGRRTVSVNIDGEWRKKRDEHG
RFIVKEGHIEREYIPISAEELREATKAVQDAIGFDAGRKDSVSVLNIKFDRTSEFDREDEHYLRVQQRNMIILYSLASVA
IVLFIFMVYKVISKEVERRRRLREEELLRQQQLMRERALWEAEQAGMNVSMSVEERKRLELQENVLNMAREHPEDVALLV
RTWLMEE
>SEQF2545_AGK84046.1 flagellar motor switch protein FliG [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVTSVKDKLATGEKKQRDIKSLNGRQKAAIFLVSIGEEISAKVMGELKEDEIEKLVFEIARTESVDAELKDAVLEEFQE
LMTAQNFITSGGIDYARGLLEKSLGSQKAIEIINRLTSSLQVRPFDFIRRTDPTHLLNFIQQEHPQTIALILAYLEPNKA
SVILQNLPDEIQSDVARRIATMDRTSPDVLREVERVLEKKLSTLSSEDYTAAGGVQNIVDILNLVDRSSEKSIVEALEDE
DPDLAEEIKKRMFVFEDIVMLDDRAIQKVLREVNMEELAKALKVVDTEVQDKIFRNMSKRAGSMLKEEMEYMGPTRLKDV
EEAQQKVVSIIRHLEDSGDIVIARSEEDEMIV
>SEQF2545_AGK84047.1 IIISP family Type III (virulence-related) secretory pathway protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPKMIFRNHEVKNLDQFLLLDLSRSFGVEPQIEEVQSEPVCPVPDMREVQEEVELFRKSWEEEQVQLRARAEREAQDLKE
RVEEEITAYREQCTQEADRILAQAKEQSELQISEAQQQAERMIAEAETSRQKICDHSKAEGIRLGKEEGFRAGQEEVRYL
TERLHKMIEEVMGRRQGILRETERQIVDLVLLMTRKVVKVISENQRAVISANVVHALRKVRTRGAVTLRVNLADVELVTQ
HKQEFIAAVERVDDLTVVEDTSVGRGGCVVETDFGEIDARVASQLHELEQRVLEVAPIVVSSMSASKGS
>SEQF2545_AGK84048.1 IIISP family Type III (virulence-related) secretory pathway protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEADLLCKYEVALRESEPVKYVGHVTAVRGLLIESRGPHAVVGELCRIVLRRQGRPLIAEVVGLAGSTVKLMSYTDTHGV
EVGCAVVAEGAALSVPVGDALLGRVLNAFGKAIDGKGEIYAPLRSEVLRASSNPMERLPITRQMVTGVRVLDSLLAVGCG
QRLGIFSGSGVGKSTLMGMIARNTDADVSVIALIGERGREVMDFVAHDLGPEGLKRSVIVSATSDESPLARVRGAYTATA
IAEYFRDQGKQVLLLFDSLTRFAKAQREIGLASGELPATRGYTPGVFETLPKLLERAGSFSMGSVTAFYTVLVDGDDLDE
PISDAVRGIVDGHIVLSRALAQRNHYPAIDVLQSVSRLAHRVLGADMKEAVRIVRRALAVYAEVEDLVRVGAYQQGSDAE
LDRAIAMRAELERFLTQGAQERVRFQDTVTSLSMLTGLSIAQPPSGV
>SEQF2545_AGK84049.1 flagellar protein FliJ [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRFCFSLERVRRLRAFRVRELEVELSKVLAEYGSIDTQIRSIAGEYRARMQDVAPKRGAVFSAASVSAVQDQIDVLQLR
REQLLHKQAHLSFTLEQLRERYAHARRAHEALLMLEEKEKTRWREQRLRAEDRACDDLVSARVPGAPSKH
>SEQF2545_AGK84050.1 hypothetical protein TPFB_0404 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKVYIHPAEQHTQRTSYLLCNLSLNEALLIDAGHVSTHLIHTIEKNSCTLTAVFLTRTDDATQAGVRTLLRVYSPHIFCG
EKCWNAHESTLLQGDCSLNCAGFTVTCFASPAYGCYLYRIAHLAFTGDLCSAGYEEAGNEADTILERACTAHETLILFHG
HGPPSSYTRARTQRASH
>SEQF2545_AGK84051.1 hypothetical protein TPFB_0405 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFEPTPYCSTSDFAKLMHTSTHIHGVYAPRMRLNRVDFSGFHFVGCNFFNTVFNACVFANVVMRMCFFERCYLVNSSFTE
ADIQFSSFEGSILHTVSFAHAVLLSDNFNRIHAQDVSFQESDLSHTRFLHATLATVRFENCTVQHTHFMPSHTTHCTFKG
SSTEHARIYLSDLP
>SEQF2545_AGK84052.1 glutamate racemase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSDRREQFQYAFLDSGIGGLPYAHALRVRVPEASLVYVADRVYFPYGNKSSAQIIARASAVLQKVQTNFSPHIVVLACNS
MSVNALEFLRAQVSVPVVGVVPAIKQAVACSHKKHIGVLATQCTITHPYTACLRAQFGAGCVFQMRADARLIECLERGLI
FEVEDMQREAVARSVMPFQEAGVDVLVLACTHFVHVRHLFQDCVGTSCTVVDSLEGVVRRTLRLCPPQSQLRGNAACYVT
GARDAVCAARYARYAQHFGLRWAGFLDV
>SEQF2545_AGK84053.1 HAD family hydrolase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGKPRFRAVAFDIDGTLYPGWRLALRVMPFMIRNARLMRAFRAVRQELRREQRTALIPFEDFFFAQATRIAPRVGLSAEE
VRAFLDTALYRGWRRHFLHIKPFPHVLSSVLELRRHGLKIALLSDFPPSQKGCLWGVRALCDVTLGTEEIGSLKPSPRAF
YALAQRLNLRCEEILYVGNSVHDVEGAHAAGMRIACVRRPFTSLRVRRSADWLFSDYRTLCAYVIA
>SEQF2545_AGK84054.1 chromosome segregation ATPase domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEYFLTVVIACAISLVMVAFSRQLDKGNRSLEKVKRYADYIKEDLESFSAEKIAMLKDAAIELNVKQEQAIASVKKMDHL
YDQFMKKSTALAAANMAVGKIHREVQASEKDVCTLREQVAVAQGLIAEVNKESSFVDSLSKRVAAAKTQLQQVSAAIPDM
QNAFTRENTALLHRVRDGVLADVHKELAVLQTRLEKAQGESQSLFEVSAVKLRELYEGAFSEATVRAQVLEENGFGQLKV
QAENRLLQLQEEFEGRLLSLQQHVMQRVEQTDQHIQDCASQWSVRAQTCESDLSIRLADVTACVDESVAQLKEQITTQER
EVRAHLEGIEQSLSGAESGLRERVHKSVTSFHENLNKIAEASDAQLQQYRKEMDGRCSKFDRELEGIDVLESQLQLARER
TEQKVREEFEAYAQDRERKQLAFEAQLQHSMDTVEHRMKQLNDELRELKASAYANASEKLQSVEDNFFEVLTKRSDSLHA
RFSEWSEGIEGRLTQLALESESARKDLEDTYRKELHTRLKDFVEEYKGQCTKLGEQILAIESNVKQHMRANDDLFQRHTE
KFTIDVAALHDKAHNLIERELEAVRQRLRDSLHVHSSMIETEVRDMNVLVQEIKQEAQGGCGSVKRDIEAWKAHTDKQFA
DAKQLFEGKIAHLVNLSERAIENLSARYDMQYEDFSQKNGESLQSLRDEIGKMCDTMRTVKEELGGYVNTVTGQLHADGR
RESEALHKTVKEARAQVDRTLQETRDLVQDLRAEFGEAQVGLLTKLQGESDRFSQVLQEIERKQHEFIGQTRIFDRADEL
RENLEKDIERLTETVTRFEVYREAMDKLSLQYEKVKHFGEEAEQRVEKFMQERKNIDLLEGEFSKLAALSDAMDKKIVEL
TLANDDLQRYQVQIRKVKEGLGDISTRYERLDKKGAVLDQTVQDVDRAFENLKELEKTLKNFRGELETVDPQLQRVRAEI
AVLLDNQEKAERVRSRIECADALLGEMESRIEKMQHAREWLAGTETRLQEISKVSEGQLRLLGDLMRQDPANKIPGAGAP
PLATRQNVVKLHKSGWSDDAIAHALKISKGEVQLILELPDMDSF
>SEQF2545_AGK84055.1 hypothetical protein TPFB_0409 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIDWIVFFALAWGRARVSCALKDENNAPSNSFANHYGERWLDPTARYRRRMSDLLPFCFCA
>SEQF2545_AGK84056.1 preprotein translocase subunit YajC [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPHRTLLQITTANGGWIPPLAIGVVCLIFYLFVFAPNLREQKRTQALIKNIKKGDPVVTIGGIHGVVSVVREHSLVIKVN
EHGTLEVSRSAIARINDRRGVSNPKTDCDSKPGVPLTGVDKEIAR
>SEQF2545_AGK84057.1 RND superfamily resistance-nodulation-cell division protein:proton (H+) antiporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSKKARFGVVLVVLAACSGFLFPTLQWYFLTDAQTRQRALSSREQIKEYAVQSAERDLADLTRLARAGSDEDISARYAPL
VAAARQNLSYSGRPAPSRWTAAALVSAFPVKSEQGFVLYARPLMEQTYREAVLKMKRRQAQAVKLGLDLSGGTSVVIKAD
LSEVTKGVPDAERAAIRSEAMALVLSTLENRINRFGLSEPVIRRQGEDRVYVEIPGLTDRDRVHSIVMGRGVLAFHLVDD
DATQKLLDHYRNNPQGTFDAAHQLHDLSLVPEHTSVLGVYRKDSYGLDVRDGFLVVKKEPALEGRHIRDATVSSGRANEP
LVLFDLDHEGARIFSELTTKEIGRRLAIVSDGKIRSAPAIREPITAGSGSISGFSAEEAQNLKTALRSAWLNVALEIENQ
QVVGASMGEESIRQGTRALVWGLCAVLLFMLVWYQEAGVNACVAQLLNLYIMFGVLSAFNLTLTLSSIAGMILTIGMAVD
ANVVVFERIREELALGKSRGAAVCSGFERAFWAIMDSNVTTFIAALFLSVLGTGPIKGFAYSLAIGVVSSVFTALFVSRL
MFDYGTEVLHKKTVRIGWRIARV
>SEQF2545_AGK84058.1 RND superfamily resistance-nodulation-cell division protein:proton (H+) antiporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRQVVRFSLLFLPCAILSVVLIGAGVLRWALWGMSFGIDFQSGLIERLRIAPPAFSLVYTGTQSMQFFQDEQKVVFTVSS
PGVLGERYEFLYTEYPTLRAFSEGAKKVEHLSVTLHAPETVYMRDTFSGAEGSTLSSASCFVHYFSEDVRAPGVEELRRV
LKDVPSAVVQQVGVRAEHTFQVRVAAETAFPSSLLPEQGGTALAQSDAPDLVTPQGAVESVVYAALVRAYGADHVVRLAM
DFVGSRFSHLLVRQALLLVLGALVLIFLYVALRFRWFFALGAIVALVHDACIMVSFMVWFGLEFNSASIAAILTIIGYSI
NDTVVVFDRVRQTILLDPIASVTTVLDRSQTDMLTRTVVTTVTTLLAALMLYVFTEGGSRDFSLALMVGMVSGVYSTIYI
AGGCIALISRGKSGGQLLGL
>SEQF2545_AGK84059.1 hypothetical protein TPFB_0411a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCRKGKERGKRGDSALPTLLFLPYNRFSFPAGVQAARLPKVEPFFFVLFQKVK
>SEQF2545_AGK84060.1 DNA/RNA-binding domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGIRGELFTTEVQAENRTYFFNVKENRVGDVFLQVVESKNVDGAGFDRHAVVVFEEEMQKFLQGFNRSLDFLEKNKKERL
HLRQARSLHTRGERKTIVRKK
>SEQF2545_AGK84061.1 phosphohexomutase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSLLNSLITSLTLPQPAQPLHLSLTRSPSGWRKVFPYAFTPERTVTLTQKADAVLSAQVALSYARFLKKKVPKPRVVIAR
DSRPTGEIISSICTAILHLEGCSLRCVGVGPIPEIASYARNYDAFLYISASHNPIEYNGFKFGLNDGGVLSPTQAQQLSE
DFVAQCLQPASFQKIREHCATLNASILEPLLYNKTHKQESLHSYDLFIREVIANSPKETEHRAFFHRFTQQRAAYSEQGT
PLSILIDFNGSARAASIDRRLLESLGVALFSIAETPGDIRHRIVPEGSSLTACAQALTEAATRGSSPEERSIAFGFVPDC
DGDRGNIVYYDQTLNRAVIPHEQAVFALSVVSEICELSRNLRMQPHRAPPIALVTNGPTSLRVEAIAQLLDVHVFRTEVG
EAHLIEKAHLLRKEGYCVRILGEGSNGGSILHPAAVRDPLHTVFALLKLLLLRGDGKQPGLFAWWCAHSHQTERAQHAFT
ISDLFASLPAYTTTPTHDTRALLQIRTTDHALLKSAYQRVFERRWAQEKDTLKKRFGICSYRPILYRGREQQDAAGDFSR
SADGGLKIQFYNEHQEAVAFVWMRGSKTEPIFRISADLKGNDEAGEAALLQLHADMVREADRCALSCADTTS
>SEQF2545_AGK84062.1 AGCS family alanine or glycine:sodium (Na+) or proton (H+) symporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGVVEWVGEWMHAVVWSFPMVVLLLGTGCYVTVCMKFFPVVRLWYVLRQTIGGRGGKKGGSGEVSAFRAVSTALAATLGS
GNIVGVATAIAIGGPGAIFWIWVTGIFGMGTKFVEVVLAVYYRRQTGDGRFVGGPMYYLKDGVGVPGAGVLASLFCIFSV
IASFGIGNMTQSNSVALVFEDVFCVDVRVTGAVLMVLVGLVSVGGLKSISWVTGVMVPGMAILYVCVGVVLVCCNTRQLV
PVCWDIVSGAFAGTAAVGGFAGSVVRQAIAVGISRGVAVNEAGLGTAPIAHAAAITDHPVRQGLWGIFEVFVGTMVVSSV
TAFAILLTGVWQGGASGAALTVQSFERGLPFGIGQYVVGVSVPLFAFTTMLGWLYYGERCAEFLCGPRVCPLYRAVWLPF
VYVGAVGSLSSVWNISDAFNGLMALPNLVGLLFLARQGMRLREEFFAQQEG
>SEQF2545_AGK84063.1 hypothetical protein TPFB_0415 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRSRKGRGARRWMSHENGVAVHGNVGVEGARKFLESRCVLKEAEGGEICWSVIVEKKVDDIRVKGEQHGGFLCAGMWGDF
VGTGEERIAGRDRTEEAHVTGKEGKVFRRQGVEGGTLRVRLEKCRIVGWGMYGGPGVVRVFCARSGGAQRTECEKGAGGV
SSDVAIHRVYLL
>SEQF2545_AGK84064.1 Sec family Type I general secretory pathway protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFEQLSASFKRIVGALGGRATISERNIQEAVESIKRALLDADVHVRVVRRFVNQTIQHAQGQTVLASVSPAQQFIKIVHE
RLTAFLGEHTRSLHLKGPDTQSIILLLGLQGSGKTTSAAKLAAYLKDAGRSPLLAACDHVRAAASAQLAVLGTHIGVPVY
QHALPHEQQPCALDTARGALQYARSHGNDVLIIDTAGRLHVDAALMQELILLKETLVPVETLLVADALTGQTVVRIAEEF
HAAVGISGVVLSKFDSDTRGGAALSLKSITGQPLLFVGTGERPQDFEPFHPERAAGRILGMGDIVSLVEKAQKAFDAQEH
ARAQKKTQSHERFTLSDMLDHLQTIEKMGPLHSLVEMIPGLAGAVSADALDARAFKRQKAIIQSMTVQERDNFLIIGPSR
RRRIAAGSGTSVADVNRLIKNFERMRTLMRKTAWQSRRAHPKGDTPYGWPHR
>SEQF2545_AGK84065.1 apolipoprotein N-acyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLCTAPLVSSAASAVLLAFAIPNEFWLAGSSVLGLGALVPLYVGFLLSPAKKHVACSYGLFVALVHACSSFWLKNFQGFA
LFTLGASTVGYFFYALPFGVAFACILRKQAPARACAFALVWTLWEWVKSTGILAYPWGTVPMTAHSLSHLIQIADITGVW
GLSFLIPLANACVAESLHFFIKKRDSVPVFRLWLLTGCLYCLCSLYGAYRIATLGAPRTTLALAIVQQNADPWDTTSFEK
NLTTAIHLTETALRTQTAPPLPTTPYRKEKTLTHASARAPVDMVVWSESSLRYPYEQYRHVYNALPAARPFSAFLRTLGA
PLLVGTPLRLSGNSTKGGYANAVALLRPDGHVAQVYGKMQMVPFAEFIPWGHMTSVQRLAQMLAGFSESWTPGPGPRLFH
VPCAAGGSVRFATPICYEDAFPSLCAALHTQGSELLINLTNDSWSKTASAEWQHYVVSLFRAIELRTTLVRSTNSGYTVV
IGPEGKTRAAFPLFQATSAVLHVPVYPVVRTYYARMRDWVIVLCALIFFAEGVRMAVHTRRHSTTQAESSLQQIRGEHV
>SEQF2545_AGK84066.1 galactokinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLYYFNTLAMMLRMQRVESCHTEEYGDEPEAIAVVPGRFHLLGEYLWFAQGNTLSMAIDQTLTLCVSRRKDSTFRLFSLT
LGERRKISTANLRYRKEDRWANSVKAVILSFMDGGYHLTGLNCTILSQIPPDAGLGTPNALKVAMALVLGRLFAATLPKE
SVVSIVEHANERYLKTHAHRADILCVLFAKQGSCVRTDHRKKQAELCQFPSEGKRIVLTDSRVPRFIAREEFTARLKRCV
DAYELVKRNPDMPRAMSKLMAAALEEIDVPEGIRRRVISLVRESLGVDEAIEALRKRDFAAFSRVVNRSHERLRDRFEIS
CPELDWLVKRALEFVDPDAPDVVCSRLTGRGFGGCTYAILRDQDFEPYLERLDEYERIFGFKAAAYEVQCSEGARVL
>SEQF2545_AGK84067.1 acid phosphatase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRILLTNDDGYQAAGIRALHAALKAAPEGYEVTVVAPDRDRSAVSHGITTLEPVTVKEVEPGIWSCSGTPVDCVNRALRQ
VCVGTPPDVVVSGINEGENLGTDIVFSGTVAAARQAVMYGIAGIAASLLPVSDFGTGCRFQALARFVARHVRALAALSSE
DVLVNINARSAQAYARACYARVARRIYEERGAVRQAGLAHVFEYQGGAAHTGAVQDSDWAVVMRGDIAITLVYAQPVSMP
PVLPLPDFAFQACCSY
>SEQF2545_AGK84068.1 NHL repeat protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRGGWCLSRRSVGCAGALLLLFAVGAQEHAPPVVRDTALAAGEFRRGVLAYYRGAFNDAIQLFERALSAAPRNPLILEWL
GNAYYRSGIEGAALHQWGAARDLGYGGALLRNKIEVVQQRRDFAPDSADALHFSESESFHAVRRGTVLFRRPLSLCALAD
GTFWMSAYGSNELLRFDVNGRVIARTRGPVEGFDRPFDVIQTRSGDLLVSEFASDRICRLTKEGRFLKSFGGKGRGVGQL
IGPQFLATDRYDNIYVTDFGNARVAVFAPDGAPLFHFGQKSARFFGFSAPGGIAILDELVYVADALKGAIYVFDTAGNYV
RTLVAEGTLKHVESVRAWNGRLLVSLPNEVMVVDVGLASLHTIARLGNAPIRLTAAVPDANGNVLLADYKNERIEIVSRI
SELAGGLFVHFERVHADRFPSVTVNVSVHTREGTPVVGLDVSNFFLTEEHRPVSEMRLQGAAYLNDTCSLSILVDRSPAT
EQEMRLVTRVIGELAQAVGEQGTLSVVSAAQSPVLEGTFTAAQLQAQPLRLRAKSSSQWRFDLGLRLAAGTLVNADYKRA
VVFLSLGELQTQDFAQYGVTDLAAYLTNNETSFYVIQLQRTVLPVELGYLVQKTRGAVYSVYAQEGLGALVAHVRSGAAG
TYALSYRSRLPTDFGRAYMPVEAEVRVLSRSGRDETGYFAPLE
>SEQF2545_AGK84069.1 hypothetical protein TPFB_0422 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRRLSDRLRGMTGKGWSAWVRLCVLSTQVGLAAEPALARLAGVWENATRIVAIAPTADAMRFSLMLVHKPYYAYVYERVA
VFSLSSLSDARADVLPPPAAQKAERVDLVLSFEGRVRVQPLVLCRWGDALFCSFFQRVSYGTRSGSVSSEQIPVRTDDPL
FGFWIEEGSAEALRAYSSQAPGELNAFFFTEANFYRFRYWRDDALAFAAQRAYFTADDGVTYEIPQYVQRGAAVYSCTTG
RSRVVRNFQTGTYEVRTSSDGSKRLMLRRCGAGPGSYAVGAVYPRQGFLDESALALRVDGQFLAIGEPFLRKSVVHDVTA
FIDAHNARKRAPRAPLLVPDF
>SEQF2545_AGK84070.1 hypothetical protein TPFB_0423 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRVFVSWHKQKDKGERERAGALQGACIGTPEHRQVFALVGRSGSGKSFRAQIVMRRFDIAFVIDDGLLIREDKIIAGRSA
KQERTLLAAIRVALFENTMHRRVVARVLTYFLCGSQNKKVLILGTSERMVRRIALRVGLPEPGHIIRIEDIASSEEIACA
LRTRHVEGTHVIPVPSGEVRKSYPKIFYERIKLLLRREAGAERIGRWAHAIWHEGLKRACSGAHAHVFEKSIVRPPFSCN
LRVVAATEGTQDASPVVVPPHEELALQQ
>SEQF2545_AGK84071.1 two-sector ATPase, V(1) subunit E [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEIQLQDLIDRIKREAVASSEEQASRLLGESREEAERIVRAAREEAERIVRAAREEAERIESSSLAALSQASRNVLLSFQ
DSVTRSLRAIISMETAQAYDAGVLRELIPRVVSAWVQAEGDKLELILSPADLRTLEGVFCAALQEQLSAGVELRSDDCLT
AGFRIVPAEGGSYYDFSAAAVAQLFSSYVSARVAEVLRSAAQEL
>SEQF2545_AGK84072.1 hypothetical protein TPFB_0425 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSSYCYLITQLPSLLCGAVPPLRYQDFLDCALRFLGRQDAAVLGNISLCPVPARDSTGSRVLDRWGEFEYALRCALARER
ADRLRWDTPVEVRQCPVAQESVARAARVAVSLDDPLEAEYFLNDARFSFVEGCRPLDPFSSEAVFLYGLQLMLLTHRSRF
TMQAGSKAYAALYYTILGAYT
>SEQF2545_AGK84073.1 two-sector ATPase, V(1) subunit A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTQTKGIVSAVNGNMVSVTFEGVVSLNEVGYVHVGNARLKAEIIRVRGREAQLQVFEITRGVSVGDRVEFTGDLLSVELG
PGLLGQVYDGLQNPLPLLAEKVGYFLERGVYLPALSRTSEWMFTPHVSVGERVVRGDVLGYTPEGALKHRIMVPFHMGDS
YEVVFIQTAGTYRVHDVIARVRDAQGHEHELTMAFRWPVKRPVHCYAERLKPTEPLVTSIRTIDTFFPVAKGGTYCIPGP
FGAGKTVLQHSTSRNADVDVVVIAACGERAGEVVETLREFPDLTDPRTGRSLMERTVIVCNTSSMPVASREASVYTGVTL
AEYYRQMGLDVLLLADSTSRWAQALREMSGRLEEIPGEEAFPAYLESCIAAFYERAGVVRLRSGEKGSVTIGGTVSPAGG
NFEEPVTQATLKVVGAFHGLSRERSDARRYPAVHPLDSWSKYPSVLDARAVAYGRSFLRRGAEVEQMMRVVGEEGTSMED
FLVYLKGSFLDSVYLQQNSFDTVDSAVPVARQKHCYAIVMRVLGSVLAFESKDDARAYFSKLGHMFIDYNCCAWNSEAFV
EKEKEIRAFLQGESTKIDSEAEGIIRGME
>SEQF2545_AGK84074.1 two-sector ATPase, V(1) subunit B [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYKVYEKIESINGSVITVRAKGVHYGELARVKTAFGDSLAEVNKLEGDVVSLQVFAGGRGISTGSEVRFLGRGMLVSFSD
YLLGRIFNGSGVPRDGGPALKEGRVEIGGPSVNPAKRVIARRMIRTGIPMIDVFNTLVVSQKLPIFSSSGEPYNELLARI
AMQAEVDVIVLGGMGLKHDDYLYFKSALEEAGALSRAVLFVHTASDPTVECLMVPDMCLAVAEQFALKGRDVLVLLTDMT
NFADAMKEIAIIQEQVPSNRGYPGDLYSQLASRYEKAVDFDDAGSVTILAVTTMPGDDVTHPVPDNTGYITEGQFYLKNG
RIEPFGSLSRLKQNVNGRTRADHRALMDNMIKLYAAYRDALEKRSMGFAMSEWDEKLLTYGGLFEAQLMDLSVNIPLEEA
FDTGWKILGRCFTPEETGIRSDLINTYWPA
>SEQF2545_AGK84075.1 two-sector ATPase, V(1) subunit D [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVRLTKNELKRQKETLKTFRRFLPTLQLKKQQLYAEIRAVEARASEVRSRADALRQDVQQWVAVFSESGVFDARLLRVQ
EVKKTYASIAGVRIPCFLEVHFACPPYDLYRVPLWVDTAVRKMQEVLSLDLEAHVLDEQALLLGAELRTTTQRVNLFEKV
KIPETRACIRKITVYLGDQQVAAVVRGKMSKKNLVDVSRMEQEDTR
>SEQF2545_AGK84076.1 putative Baf family transcriptional regulator [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLLIDVGNSHVVFGIQGENGGRVCVRELFRLAPDARKTQDEYSLLIHALCERAGVGRASLRDAFISSVVPVLTKTIADAV
AQISGVQPVVFGPWAYEHLPVRIPEPVRAEIGTDLVANAVAAYVHFRSACVVVDCGTALTFTAVDGTGLIQGVAIAPGLR
TAVQSLHTGTAQLPLVPLALPDSVLGKDTTHAVQAGVVRGTLFVIRAMIAQCQKELGCRCAAVITGGLSRLFSSEVDFPP
IDAQLTLSGLAHIARLVPTSLLPPATVSGSSGN
>SEQF2545_AGK84077.1 hypothetical protein TPFB_0432 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSGGVGVGKRLCCIALVMRAFWYLSAKGVSIAYVPVHRSGGSQDSSMSTAVGDTLLNAFFDEGMVVTAVPPGVHDGQTIA
EIAACFEVMPDYALLVQFHSARLPGGESPTSRARGAWSSERFRAVWTLVDLHTQRACVYACVAPYRESIPVSECVDVVTR
CIAEQAISCIRVGTSTDTAGVQL
>SEQF2545_AGK84078.1 acidic repeat protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIKRHMFAKRGVKGRSYLVRVNTAFLVLCVASVTPLWAVWEGNAEIGPQGSFLQDGMFVRSDMFPKNTAVEISNLEKNAK
AQAVVIGHAGIPGLLVSLAPAAAAQLGIGVYQAVRVRVRTLGTVRGGSQTSQDGLSLASLPSRVPARPAQRDPLSSPPAG
HTVPEYRDTVIFDDPRLVSPLSREVEDVPKVVEPASEREGGEREVEDVPKVVEPASEREGGEREVEDVPKVVEPASEREG
GEREVEDVPKVVEPASEREGGEREVEDVPKVVEPASEREGGEREVEDVPKVVEPASEREGGEREVEDVPKVVEPASEREG
GEREVEDVPKVVEPASEREGGEREVEDVPKVVEPASEREGGEREVEDVPKVVEPASEREGGEREVEDVPKVVEPASEREG
GEREVEDVPKVVEPASEREGGEREVEDVPKVVEPASEREGGEREVEDVPKVVEPASEREGGEREVEDVPKVVEPASEREG
GEREVASQHTKQPSHSVSNSAPNQFRNPEGELPFTLPDLSESEIVVPEEQKGRAHPQVIPEGAPRGLQPGEYYVQIAVFH
DAIQVQSIVHRYGVEYPIAVEQDIHEGKVRFTVCVGPVQKDERGAVLENFQRFGFKDAFLKKAR
>SEQF2545_AGK84079.1 copper resistance lipoprotein NlpE [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKGSVRALCAFLGVGALGSALCVSCTTVCPHAGKAKAEKVECALKGGIFRGTLPAADCPGIDTTVTFNADGTAQKVELAL
EKKSAPSPLTYRGTWMVREDGIVELSLVSSEQSKAPHEKELYELIDSNSVRYMGAPGAGKPSKEMAPFYVLKKTKK
>SEQF2545_AGK84080.1 hypothetical protein TPFB_0435a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRGGLRSSLTFGKRERNFCIVGLFSPESYRRDKGVFCDERICPRAVRVPWCWSAR
>SEQF2545_AGK84081.1 DHH superfamily phosphoesterase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFSSSPPSSLPKSVSSPSPCAARTGDRGRGLSGLIEFIDAHRAFAVVGHEKPDGDCVGSSLALASFLRRIGKEVELLSAG
PFKRREIAAYATLFRPSLSAQIRPSDQTAVIVVDCSELSRVGAELASQLAPFARAFIDHHETCGDHCAHSFVVKTAPSTT
TLVQTLIETMAGSLEAAEARALFLGLATDTGFFRHLDEHSADTFASAARLVRAGANPKDTFLAMNGGRSLASRMLIARVL
SRLTPYYGGALMTSYETCEDAVQLGLDVRDSDALYQLIQSIQGVEAIVVVRQESPTHCSVGFRSRGSIDVSVIAARFGGG
GHRCAAGLRIEGTVDELLPRFVAAFEAQMRAPAAGAQVRS
>SEQF2545_AGK84082.1 hypothetical protein TPFB_0437 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIQTLVLRDTPRLESCRRGGFAMKFSTRCLRLVLCASAVALSAQDASDTAGRVLEPPPPGLTESNSSRMYYVNLPVVKVF
SHRLGYRVIYRRANFEMAEIYLPSAWFSPRVGKALLRHAPVRVDPYLSFFMEGNTLTYVKLTLPRSLSSPVWGTLKSPSE
YDDKFDVQFQSPEFSS
>SEQF2545_AGK84083.1 HAM1 protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRAVDFLRRATVCWYMRIYLASNNAHKHAEFSSLFPMHTILLPKDEGIDFFSPEDGSTFFANARQKADALYDVVHAPVLA
DDSGLCVDALDGDPGVHSARFGAQHGVHTDTARMQLLLERMHGRQDRACSFVCVAVLKLGSVPLCVGRGVCRGVLTTEMS
GVEGFGYDPIFLLPHLGRTFAQLSIEEKNRVSHRALAALRLAQVLAMMQLPRALRYELKLLRGARRMTRGGVLRPGAPCA
QRKGQTAQTARRHKFYARARRCARRIHRA
>SEQF2545_AGK84084.1 chemotaxis protein CheW [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYHGPTLHHRRVPMAVNDEQFQLVTFQLGEELYGIDIMGVKEIVKVQDVRPIPCAPAYVEGIFNLRSEIIPIINLHKRFH
LREATLESGDEYLGGFVILNVEDSKLGIIIDRIARVIAVSQEDVQSPPQVITGIGAEYIHGVVRQGTSYLIVLDIHKLFS
SKELQKLANL
>SEQF2545_AGK84085.1 pyridoxal phosphate-dependent transferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDAVLTCLVDEKIGPGSLGSTLIQLVREVFSPIDAYVLRSPAIALSFALRALKLPPASPVLLSALAPFWHYREVLHQGLQ
PLVLDVDIHSGLLSRDVVETGIARGARALLVPETLGNVPPAAVFLELGIPVIEDSSQSVGAVLGEKKVGTFGSCVIVGLE
AHDMLTAGGGAVLMAFEAACARRLQALVPEALAVDMLPDMNAALACVQVKQQEKNIALRRAIYDRYSSALLRTRHGTLHR
CEQLEHSAYAFPVVLASDLKEVTRYVRQASIEISPAFEHSIVAAFQLPAMRRRWPFPQFLPTSASHTAPFQGEDREVLET
TQGAEKTCQDSSWEREVRASEITPEMCWPHASALLLRCVRFPLYPRLAPAHAQEIARILGTLP
>SEQF2545_AGK84086.1 putative inorganic polyphosphate/ATP-NAD kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSSRVCPQRPVAKSSGDAKVLLIVSTYKPRAAVLAADVVNFLSIRGFQCHTIEYDGLNKESCARAGYMFAVSIGGDGATL
FAARCASPSGIPILAINLGRFGFIAPIEPRYWQQALSDYLAGGVRPAERALISCTVTRAGKEIASCLALNDVVLSSGRVA
RLTRAEVCFNDISFGVYEADGIILATPTGSTAYSAACGGPILDPDLDAFVLTPISALCLSNRPVVVPSSGVVRIKVLSMR
HKETVLSVDGHELCTLQEEDQLLASRSSCSARLVFCTPHVFYHALCSKLAWSGSIFSRRGRRHDD
>SEQF2545_AGK84087.1 DNA repair protein RecN [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIEQLSVRNVALIQSLALEFGAQFTALSGETGAGKSMILGALSFLCGQKVGPDLIRKDENEAWVSAVFRCDHAPRAVHTW
LAERSIEPEHHRVLLRRVMRRTGRGTAWIQNVPVSRADLEFFTSFFIDLHGQHEHQSLFRVAEHRRFLDTYGGLQQEVDA
FTACYAALAERRAQLQRLASCEHNRQERLEFLSFALEELEHAALDVHEERALEGEEQKLCQHEKLCDVMQRVDAAIRGVD
LQEGALLSSLKKALGALESACGIDGSLEPARARLESAYYEIEDVAHVLRTYTDGIQFCPDRLQHVQERLALIYRLKKKYG
GTVAQVLEYRARAQQEMQDLSQAVGDKEALEQDVQRLMAQVLHAGRALSLKRHAVAEAFRTRVEGVLHRLGMASTRFHVQ
ICTRDEQCAKQRTGPYGFDDVEFLISANAGEPARPLAKIASGGELSRVMLALKTVLSSVDEVGTLIFDEIDVGIGGETAR
AVAEHLQALSEHKQVVCITHLAMIAAHADAHVCVKKESSGEHTNTSAAHVVGERRVQEVARMLAGDTHSATSLAHAQELL
RAGARQRRGECGD
>SEQF2545_AGK84088.1 hypothetical protein TPFB_0443 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRRSCCAQVRGREGGSAVTEEEQNALYQKKLNVYQGTIDQIFTREKNILELIRRDGTGAAYKKLALVDDMIYLSTLYAAK
YQTQVVVVGGKQEDLLNEARKTLYKALIYLEEIVTNLIDAPFSDYQEQVAQIANVSQQQRYYLIRKMGLAIDSIISAYGT
NTKWYWSFVELQARYATVAKNILDLANSSEIGLNPQADEYETVVYHLRLVKKLLLQAAERYREKYEMTSSSFEDFKLAVC
YLHALRRVHLLLNERQDAEEVKKKAKVWSERMEKDQRKRDRSDK
>SEQF2545_AGK84089.1 LysM domain/M23/M37 peptidase domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRAPAGCGVSRLRVNVCYLRQGERARIGDAHAFFLSAEKGAGMGGFFLSLAGCFLLAAAYGAAQTVHVIAKGETLFSLSR
RYGVPLSALAQANNLANVHQLVPGQRIVVPRGYTVRRGDTLFSIARMLNCSLAALLAANGISAAHTIHPGDVLVIPPREK
SPPTVAGADRILSVSSLPDGDQWARARADPVQTPVSPPAAVPAPERREISLRDPRQYISKKVDKNARWPVSPTSLAYVRG
KTYGVVIDSERNAAVRALMSGKVISRGTHRGYGQVLFVESAGKHVYVYGGLERILPKSGDYVSAGDVLGNLGFDAAAARS
RLYFMVYKKNKPIDPAQAPRGF
>SEQF2545_AGK84090.1 DJ-1 family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSVRVYLFVAHGFEEVETITPLDYLRRAGIALTLVGVGAEQVVSTRGLRVSCDCSLEALCASPGIADAACAADAVLLPGG
LENCHTLAACAAVRDFVMRVHLRGGLVAALCAAPARVLSAWNLLGSRRYTCYPGMEPAVFSAHDDGVGKRTEEEESRALR
KPERARVVRDGNLLTACAAGAAEEFSFAVIEALCGVEVAQSVRAQVVAR
>SEQF2545_AGK84091.1 (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNQRDERAARQPEEKVDSSAGVSPCNSPYGSGLLDVPLKLRPRASHYRARSLVIGGKEHVRALPLGGDAPIPIQTMWKEP
LIGADLQSIVDRLLELEQLGCDVVRFAVPDRESAELFVALCARTRMPLVADIHFDYRLALRCMDGPVAKVRINPGNIGVR
ERVRAVVEKARATGTALRIGVNTGSLPGVVKRAVAARYADGMQSVNARAEALVQTAFAETAYLDQLHFDRVVLSLKASTV
AETVRANELFAQQSDIPLHLGVTEAGPLVSGIVKSTLAFSQLLSRNIGATVRVSLSDSMEHEVLAAREILAECGKRAGGV
RLVSCPRCGRIGFDVHAFVRRWQKELFSLKKDITVAVMGCVVNGPGEGKHADLGISGAEDSVIFFKRGKIVRRIQVRDLC
ADERTRVIDAAFKEELSSL
>SEQF2545_AGK84092.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNNLIKAYAAGVMSAAFLFGSEGRVRSESDRVRGEDPWHLLQWAQVVYEREEFGDTLRYAQRARALRREQVEHQCRVLLR
ARTRAESAGIPETLSDLYALLKSRGETDACEVLDAIFLTHAPHVFQNSVSKLLQWLKDSAAFPEAELLLGKVFEGEGEYA
QALQHYRNAWDTRAQLVVPDARFDIIYAMANVSRLLSQQDEREKYLLLVLSEDPLYSAREVWGKTLHAMLRTIRSSNTVE
KFFKLYRHRNVLALRAYQELTEMYVRTDNIERALPVSVLAADIAISALDSFLQKIEFTYQYKDLADLFLRTGSHPTILKW
ANEHGVWQTLLHFADLLYKKGLHAQARDMYYNLAEKCPAFEYARRAAYKLSLTL
>SEQF2545_AGK84093.1 uracil phosphoribosyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEGQTARRVITEAKFLDDCLTERDSYYLSKLDELYSSAMSSFAQFEDQQNGARSARAEENIIATYDSIGNLMQEICKELP
ALKVYSFETQRENHAEVSRVVSKLRNIHTGYSEFIYYTQRAFEMLFRLAYGGSHEEHKTYLITKTPVAFPVQNYAVHKIA
NVDYKIENTVMCVMLRGALLPSMIVSKEIEEYSSHGYVTPFALFKIKRDDLRDERDMQYVFDLDKSYFSARELDGKDLVF
ADPMNATGGSLVTIVRYLQDLGVKPKSISCFHMISALKGAIRVVRSLENCTVYTLWMDPVLNARAYIMPGLGDAGDRVNG
VDVEDYPRNIIQLLADYGSNISGLYRSQLRKIEETVLGSR
>SEQF2545_AGK84094.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNGKQCFCFFLFHLFYTGLFACGKPESSLAPEYFDLAHAYVQLHRYDEARDYYMRAARDPAYYHAAQYNFARVCGLQNDW
KTAVHALQPLYDADSANATIAAAYAYALLSFGETARALLLYQQLYERDQKNTQRILEYANVLVHAKKYIQAVEFLRQKKS
LLSEAEDVRVLQSIVRKLKDSVPPHLIADFVSTDDL
>SEQF2545_AGK84095.1 elongation factor EF2 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRQQQMRNIGIMAHVDAGKTTTTERMLFYTGKIHRMGEIDDGATTMDWMVQEQERGITIQSAATTVRWREVDITIIDTPG
HVDFTAEVERALRVLDGVVVVLCAVGRVQPQTETVWYQADRYDIPRVCFVNKMDRIGADFFSVLDQVHNKFGIDAVALQI
PIGSGTSFEGVIDLITMKEIFWDAASSGEQMEYRPIQSARIAQAREAREKMLDVISIYSDEVTECVLAGEHVPVQLLHAE
IRKAVRERRYVPFLCGSSRHNLGVQPLLDAVVEYLPAPQERKAVEGFHVQKKEPVFIAPTAEGPLLALVFKIQYEREAGL
LCYVRMYSGKLRTGDSIVNIGKKKRERVYRILRMHSNKSETVECIQAGDIAVIVGLKSAQTGDSVGDGSCPVVLESMHFP
EPVISVSLEPMDASSRDKLQETLGILSREDPTFSVREDAETGQLLISGMGELHLDVLTTRMREDFNVQVRVGKPHVTYRE
SIRKTVERTLRVQRVIGGKEYMAGLTLRVEARKRGAGNEFFCQVKELRGTVCTAHTAPAEIIGAVEHAIRGAWDGGIQSG
YPCVDVGVHLLSVEYQELTSSPFIFEAAAVQAFGEACVAAEPYVLEPIMSVELSCAQENVGDVMNVIIQRGGIILGMDSK
HGRELVHAQAPMKKMFGFSTDVRSASRGGASFTMRFSHFESCA
>SEQF2545_AGK84096.1 NCS2 family nucleobase:cation symporter-2 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGCGSHCNCNVGYHRSLHCYGNELHGKQCGFSRRGEGFPAFVAVLMMPFSYSIAEGVMWGIIAYVILNAVIGRARAITHT
WGIWCRWGKVWRPS
>SEQF2545_AGK84097.1 isoleucine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYTPVDPKVDFVAQERRILAFWRERRVFEQSVAQRAQGKSYVFFDGPPFATGLPHFGHFVPSTIKDIIPRYQTMRGAYVP
RRFGWDCHGLPIEHLIEQELNLNSKSDVESYGVSAFNAACRSSVLRYVKEWQRTLTRLGRWVDFDNDYKTMDVCYMESVW
WVVAQLWQRKLLYEGYKILPYCPRCATALSNHELNLGGYQDVSDPAITVRFECTSVVPGSPAAREFCAAASWGSASLPAH
TCFLAWTTTPWTLPCNAALALGPQILYVLIEANDEHYILARSRLEFYYPDSSAYRVVWEKRGEHLAGIRYRPLFSYPVFG
QGPDPSVQGDSEEGLFCTRVADFVSTEDGTGVVHVAPAFGEDDYEVFKDAGISIQCPLDAECRFTAEVADYQGLFVKAAD
KAIIARVQKQGALFRREQISHAYPHCWRCASPLIYRAVHSWFVAVEKIKDKMLAANASICWQPSHIRDGRFGKWLVCARD
WAISRDRYWGNPLPIWRCVHCGATDCIGSRTQLYKRSGMLLEDLHKHVVDMVTIPCACGSVMRRVPEVLDCWFESGAMPY
AQQHYPFEHATDFERYFPAHFISEGLDQTRGWFYTLTILAVALFERPAFENCIVTGLVLASDGKKMSKALRNYADPNEVM
DRYGADALRLFLVRSAVVRADDLKYSDEGVKDILKTVIIPLWNSYSFYVTYANIDGIDPPVCAKVDGMGQAVTRLATHLN
NPLDRWILSLTEKLVQDIACALDAYDVSKVADPIVSYVDQLNNWYIRRSRRRFWKSINDEDKRCAYNTLYCVLKRCVLAI
APVVPFITESIWQNIRAADDVQSVHLADYPVCTPMVRDDALEFKMETVQRVVSMARAIRAQCNLKVRQPLKAMQVITRNP
MERSALLEMEEDVLDELNVKELVFHEKEDEIVEYRAKANFRVLGKELGSKTKRAALSIERLSSAEIQEILEGTTLYLDVD
GDRLELTEEKILVQRIERESLKAINEGTLTVALDTTLTEDLLLEGAIRDLVRGVQNLRKERGFSLVDRICLRVFSSDQDI
VCARKAYDLHRSYIVGETLAAHVQWARVRDGASAVYVKSDAVLWEVSIDKA
>SEQF2545_AGK84098.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRRRYRGCTQGAWIVSVGMLFASCTSGAWKASVDPLGVVGSGADVYLYFPVAGNENLISRIIENHESKADIKKIVDRTT
AVYGAFFARSKEFRLFGSGSYPYAFTNLIFSRSDGWASTKTEHGITYYESEHTDVSIPAPHFSCVIFGSSKRERMSKMLS
RLVNPDRPQLPPRFEKECTSEGTSQTVALYIKNGGHFITKLLNFPQLNLPLGAMELYLTARRNEYLYTLSLQLGNAKINF
PIQFLISRVLNAHIHVEGDRLIIEDGTISAERLASVISSLYSKKGSS
>SEQF2545_AGK84099.1 hypothetical protein TPFB_0453a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPAADVDHGRTTRVGVRFFCESCGSEVKRDARLCVHCGSFFSSIRCPSCKHAGNARDFEKGCPSCGYAFGNENRRKGSPP
APKGAPRRAEEALPTWVYAAICLLGVCVGTVAMWYL
>SEQF2545_AGK84100.1 hypothetical protein TPFB_0454 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMKALLVADDPVSVNLVFENHTQCGYEVIHYRSALKALDNMEEIQPQLLFINASDFPRHWRVLTQFFKHQSVCGARVILL
VNTPSSSLSARQVAQAGVHALIDYTLSPEEGRKALCGVLTPSACAGSVDVGHAHTCQADFVFTNPCSGSIVTGTVREVSE
EGVDFIPDFPASVNNLQEQDVLEHCALKVAHDILGVRCSFHSSDGRILLRFIDPDASLVHAVRSVTGTT
>SEQF2545_AGK84101.1 hypothetical protein TPFB_0455 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKLKRSLIVGGGLLLCCAHGYAQAKGARASVHIAYHNRTIYFPGTHESEPIWVKVSLTNTGKDTLRFKLADDRTFSVDFS
IRTMKNRALAHTDEWIRKRSTHRPVYFREISLEPGESYSFVENVKHYLDVQSAGLYFLTLLFYPELKRERTGDEDHLASN
TLTLEVQPAPAAAALGALPVSPPVGEVLQPQRLSPDRVIEYVLNARQKSHWERFFLYLDLAKMLSRDAGRSRRFNAESEA
GRYNMIDTYKHELRQERVDKDIAAIPVEFRIEKTVYTATDAEVRVLEWFEYRDFREKKRFTYHLSSRDGIWYVHDYVVEN
LGTE
>SEQF2545_AGK84102.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNTRLALVLCAVGSGVLSFSCARTAEPTPAASTHVPVTTAGALSVTPPSSTDRWYQFSRTDGRVHLRACPAPSQPSAPEH
FVPWTEAVRLSAVDAQQELLLINRAGVLPATQLARMQTAPVPRKAPSTPAAETTSLTLTPPALLATQSAEGFYSEPIPNS
SPHPCQGTGAVFVRLYTDPLFTTSPQDSAAPFLVRYDVRTARWTSVAYTRALGLPRNAQCTALTHTRGTWYASFKSSEAE
RVSFAYFSFPSLSSLENLGPTQRREHPIGGKVQVPRPISAAAFRAACTPQRLHLPTASTSSDHHSDLHELLVHRLLARVP
LSPLYLSARSPCWASDRSFLKTAHRTADERAHHANALIFHPPRARLSAALLTDSGHLYFVREDGSEGHARLSALPPQFVY
TSFTLSGPSLIAGWEEQDFFQVGSTGLLCTEVESLTGT
>SEQF2545_AGK84103.1 hypothetical protein TPFB_0457 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHLPRGLWAMGTVRSCFFPPTRAPIWGRMSCLGARARGVLRISLVIMLQGLLRASEVDEELSKKYSIEIMVDSGVSETGE
RLPLLPFERIPDSHHVRRVITQDWFLDEPSRVALRAPRSYTDETGNSFCVEAYVIAATDHLAVRVTPLLADRAPRDGVHS
APVAAAPRLHLALEAPTGTSRAGRTGADTPQSPVTDAAPSQAVAQGTWVLYRHMHTGAPVCIRVYPRESASLYVQLSAPT
AVEMQGKTHLDVCLFNVHVRKHVALGLSFEQLYTYSLLQLRALTEHAVPWRIFDPPRTYSAVESMASIIKRRSYRLAPLE
DGCFNEWGRPVHISDGSSQSDQEIIRALRVDQVPREIIGGVGSLGFAKWVVDGIIAPVAGQGVYLSALKKQTTMPRTHFN
AAHERARAPFFGIDWIRNLAAAALSLNVRRTVYPAQGGVDVTVEPFAVEGVPKGRIKQEARHPGIAPPSTPAGAVPPRVT
QGETAAGPSRYLGYLPHAGYQTGYVRALFYYLAVMEPGHFYLGVLNEERGVPRLREYQRAAVFLPYFDRSGRFQVEVFEA
ARLSTLEEFVAQYPQQMLALVRVRAPEIGHFNP
>SEQF2545_AGK84104.1 putative transcriptional regulator [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDQAEPCTLHGAPAPDLALLEAILFVEGVRLSYACLARKLGLSEQAVDECVARLGEALASGARGGGGLELHCNEQGVALL
PAATVRERLATLYGKRSEGRLSRAAMETLSIVAYAQPVTRAEIEAIRGVGADTMIRLLSERRLICEVGKKDIPGKPAQYG
TTEEFLTAFRLRSIADLPKLDEEEQRRFELTR
>SEQF2545_AGK84105.1 RsuA family pseudouridine synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQGRVCRLQPFFRLRLQVYLARSGCASRRACEALIASGRVTVDGQTVTTQGRTVCAQNVVCVDGTVVQLERVQRYVLLYK
PVGYICSLAPQFPAGYAHTQVRAGPSKQEYARAIDLVQPAYQERLYHIGRLDVRSEGALLFTNDGSFAQALGHPRSGIEK
EYIVETREPVPAALLSSFVRGVWVEGCRYRCVRARHLAAQCVQLVLVEGKKREIRVVFEAWGQDVVRLVRVRIGRVRLGP
LRPGAFRTMRLQEVAQLLQCAGCAR
>SEQF2545_AGK84106.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGCARCSYFAGAAGILRAHTRSRRGGGRLVNQFFEEFECPEHGRQPRGVQETAESLNCLALSCARKGWYEETVACLRKGL
GLSPFNGLLWLNLALGYYALKRTVDSAGALYHALRCTPHHAAVWNMLGVVLHDMGDTEASRNAYEHAIRLETKNGATWNN
YGLLLHTEQKYDQAQRAFETALSLLPRSGSALYNLSRTYHALGDARKAAVCRRILAQMPAGEKKPGPITPFALHP
>SEQF2545_AGK84107.1 putative transcriptional regulator [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLQAAACGAMRGGVLEYTGKMEGMGVRVERVRCEQNLSKTAFARELGIGVEELDAIERGTMPLSRDLTLLLCVVFAVNRL
WLESGEGEPFSASAVSPQETVQPEEEAREPPIPPPRWRG
>SEQF2545_AGK84108.1 hypothetical protein TPFB_0461a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDYSSFQSFPLFPPITALMQTWHVPAPITGTETPPEAAIRATGGGVSEVRALPPPVVPFPEERRQMLKRVPLPHFLTRDG
>SEQF2545_AGK84109.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MERIGKSCSPSRWRLCARRGRAARTADGASRVVRRIVCPPVLFLSASLLTGCDFSGIFASIQSEVPLKIPSIRGVVTGLV
KCNNKLYACAGQLWEKDASKPEGGGWKVVDFLPGKTITSIVSKGTCVFACVSGEGVYTYTSNGAGRTGGTSTTPTVLNNT
SGATRIGGSNNPFLQMPCKSSSGSSGGGGGGSGSSSGGGIKNGSDENVLGSGTGYVVTTKAVYTKSNGSGTGCTYTKDST
FTATTSPILGCTSDREGCFYVLDGTDVHCRTVQASGGSGSGAHCAVASGSANSCKVAHTVTNPLCIAHVKNGNTEFLLIG
GSQGYKEIKLETGSGSGAGCLKAQNVRGPEQWDENSVTPKGSVSQYESTIGRFAISDIYTVDSTNGASGGNGGSGTKPDV
YVVVGDSQDGYTGLWRFDAQKKKWNRE
>SEQF2545_AGK84110.1 tRNA (guanine-N(7)-)-methyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTNDSARMRKVLTFTRRSNRMTACQKRDYQHLASRWIIPYQNTVFDYAAVFCSPAAPSAPAGAFPAPQGETDAVAPACAP
APLVVEIGFGMGSATAAIAARNPHLSYLGIEVYRAGIGRLLRKIEAERLHNLRIIEHDALDVLRTMIAPQTLAGLHIFFP
DPWPKTRHHKRRLLYRPRTDLLARALAPGGYLYAVTDWAEYARRAQEELARTPSLTWAPQGARPWRPATEFERKAQTQGR
AIHELFFIKA
>SEQF2545_AGK84111.1 hypothetical protein TPFB_0465 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSQVLTVLHALSSPPWICLLSFNRMVLARQCAFVLVSCVVPCVAGAVLSSCMPFYARTEGLTLKRVYFEKAGKTDATLAL
HVTLEYPAPPEEYFYLEVEELRTGMRWVFGEKDTRVYIATDELHPGRRMLRVGGMQYPWGDFPAGTYVVYVRDSTGTYAQ
QRVTLGAGYPAHEPFPFSFSVDAQRWTLSAPAQPALVGPFTAHTHTSLVLLTRDYRTVAQHPLSLTSLPNARLSSPRVHT
FEASMDALKTTHQDAYYLQCVVEDFQRSWRFISQPHRLYPEDALSEQAPP
>SEQF2545_AGK84112.1 hypothetical protein TPFB_0466 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSSKHKRRILNLPLKLVLTQEGSEFFIKQNRKLMKLKLAEHVEDYGIALDAFAPKTVQGLLLSGYVSLIEVSPPEFASSR
QEIIDLSKLIVHSILYRQYDCYVFRQILNSEVIKKWNRSNPGSSIDEHANLNAPFIYNHLKQHEAHVTQIKHHILRLLHA
SLAACEERTPKEKNTLLFLGEKFLDTLRPFTWFIISKFQHAPDMGSVLSSIHTSLAQYLNKARIAEYIALVLVELLINEE
NTNLKKEVQKLFPDLEDAQEALCDEGIRRRIVAELKHNAESLFISWKLQGRSVSTAGTRRKLKITVYGRNDYPQEMRNCL
QDAKVVNADTDTLVDYCQQTIDTAKHANLGVYYISYLSEACKEANVRFESSLNRFTRSEFTTVDLSFEF
>SEQF2545_AGK84113.1 hypothetical protein TPFB_0467 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNSYFSALPLKCVRRPFILSRNEGWGIKRFYVADEPHRSFLCMQEGVRRGGGESEITQRKADVLRKSIRSADRYKEDRSC
RT
>SEQF2545_AGK84114.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNNVHKTFIALAAGLVLLLAVVAGFSLFSRGVVRARLPRAAGETLLEEEGVSEQELAWLETNQLLQEQGEEPGVLVDHHV
QLSGNSDEEQFLQTLSEELAPQRPVPYAPTPRERMQEQDTRQKGARVLTPPRGVSRTASFSPEKSIKRAVQIATRPEVRA
PAETATPQHHVHALLSEGKELTERRDYPGAVRVFNKAIRALPAGDAVFAADAYTRMGEAMYALSQHDNRDGFERTRALET
ATVYVKEALRLNPRSAAAHYLAACIADAQPDDDQTTALTLLERAAALDRREYRYSYELGKRLFAVRRFAEAQEAFNAATV
ANPKFEPAFFNLGLTCRVRAKHDLALQAFRAVIRLNPTHTRAWIELGRVHDAQGEVSAALADYQKAQECAAAAEAHDLYL
TAARERARVLAKSGAKEEAVRLFQEILERDSEDALTLYNLATVLLDLDRNEEALKHAQQAVYANGSQARFLYAYALAAQK
TGRVDLALTQYQLAAARDPAHVKAHNNLGKLYLDKGALQEAETHLQAALAHDAQNFEVNSNLGKLYVLRAQWETAIAHYR
RAATAQPQDREAQCQVARVYVAAGQPHEALRAYRAVLAQDARAWDVYLEAGKLAIKVNEKEYAQEVLTQLLDRNPDYAQA
PHVRQLLSSL
>SEQF2545_AGK84115.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCQKSSPCTYARVRSLPSVRLFSFLALAFASFLRAEDAFDHFREGERLLSLQQAQQAIGPLHKAAQQKPAHPKAALYLGM
AYLQTGRYTQAIQWLQNPPVHSQEYAHLYAYNLGNVYFVQHRYEEAQHAYEQALALKHDYPPALLNRANTAMKRQAYAHA
LADYKKYVSQNPTASQHYEVQRMIAALEQWLRRKEAEEARRKEAEEARRKEAEEARRKEAEEARRKEAEEARRKEAEEAR
RKEAEEARRKEAEEARRKEAEEARRKEAEEARRKEAEEARRKEAEEARRKEAEEARRKEAEEARRKEAEEARRKEAEEAR
RKEAEEARRKEAEEARRKEAEEARRKEAEEARRKEAEEARRKEAEEARRKEAEFEALKRALRLKQAEDARTLSTGSEDTV
PYQEEHNLE
>SEQF2545_AGK84116.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAHLTFLLGCATMGGMSAYMALLAAAFSSSIVFLLVFLMRGFSIPRRQLLVEKSFRDGKYALAIKHAHAVLAKDPHNWAV
RVLLGRAHLAEGKRDVALMELRAASSRAAFGKVVDEVEFRKTIAQLYLQFDQIEEALKEYTLLIRLDPTCADYHYRIGQL
FERKNVTDRAAAYYRQCIGMDAAHPAAHAALGSLLLRSGHLVEARAELDTVLALEPANAEALFCQGQLLRKEREYAAALR
SFEQASRSPVLRQKCFTERGCCYMDAKDVDRAIVEFDRALRCKSQSGENEDLQIRYLLASCYEKKRDVEKAIEQWEAINA
RSAGFKDVTIKLAQYQDIRLNDRMKEYLTLDGDSFFDLCQRIVSKALRLSIDSVQDVRGCCEIVATERDEKGWSNVRTQP
KVVVFYREARVLDDSFLRAILERMKERGIARGVVVTSSSFSRAALSFAENRPLELLGKNELERLLDASS
>SEQF2545_AGK84117.1 excision endonuclease subunit UvrC [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRPSESLVETLRIQALSAPSTSGVYLWKDVHGVVIYVGKAKSLRTRLTSYFRCRHDPKTRVLMSRAAALEYLQTQHEYEA
LLLENTLIKKHTPRYNICLKDGKTYPLLKLTCEPFPRIFRTRQFCQDGARYFGPFPDVQILDSFLKLILRTYKIRTCTTL
RKRKNPCLYYHLKRCDAPCCGWVSPRTYQKDIHEITLLLEGNIDATVARLEKRMKRAVRQEAFEAAARIRDDIQAIRCIT
HKSLVQDMDERARDYIAWSSTGAIVTFAVLRMRGGKLNGRELFRTRSLKNEEEILSEFLITYYSDHTIPPHLFVHSSAGL
AEHWLSHKAGTQCTVTLIPLHTFPTPQTPSSTVTTNAPTLAASQNSNAVQDSGLRSCSETSTMHTLQKAHDACTASEGTR
ENTPHESAHTPHHRAILAMAQLNAHEDITRYLKNRGADDALKELQKQLHLARIPTLIEGFDISHLGGKYTVASLICFKNG
APDTKNYRLFNLRAHDTRIDDFASMREAIARRYTHTPEGYTLPDLILVDGGIGHVSAAQHVLDALGLSIPLVGLAKRAEE
LFIPNSPTPLVLDRRNPALHMLQRIRDEAHRFAITRNRHLRTKKELVLSFERLPHVGKVRAHRLLAHFGSFRSLQSATPQ
DIATAIHIPLTQAHTILHAATRSTTAPVREEYKEHEHDPQGESPGPGRKTD
>SEQF2545_AGK84118.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVTVSIVEIFLIISLPLLFFSSFADAGDPLQELISFVHGAVLAVPLLLLRSFFLGYYPPDSALVEEQWMRFFLFDYVFPL
FCLPFFLFTSRSLERVSLVSGVSALFGAYTSFFFVHVYTQLNDPDLLARVMTLVLYMTNLLQLHAHVSFSMRTRLPLLGL
IAALCIFLLMGAFSATVMTLCFFNARTVVYTSMLAGAGGVALLTHFFAVRMNVR
>SEQF2545_AGK84119.1 hypothetical protein TPFB_0474 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSGHSKWATIKHAKGAADAKRGQLFTKFIKEISVAARMAGGDPQANPRLRTAILKARAANMPKDNIERAIKKGTGELSGS
SYEELVYEGYAPGGVAVLVEVLTDNKNRAAANVRNLFSRNGGNLGSAGSVSYMFNRKGVIEYDSEQVDEEALMELALEAG
AEDIQNAGGVLTVTTVPGTFETVLESLQAKGWESLSAGISMVPDTYLALDEETARKVLKMIDRLEEEEDVQAVYSNADIP
SELVL
>SEQF2545_AGK84120.1 glucose-6-phosphate isomerase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNWRNLDECAAYARLQAIRAPSLKTVLCGPEGIERVRRYCTDAGAGLRYHYAAKTVNEEILTALAALADEQELVAKYDAL
RAGAQINTGEKRRVLHHLTRLGVQGSSLASLPCEVRDMHAFYTKEYERVCAFARQVHEGGLRTSRGAPFTDVVQIGIGGS
DLGPRALYLALEGWAQRHQAVKMRTHFISNVDPDDAALVLSKLPLETTLFILVSKSGTTLETLSNELFVAHVLRQAGLEP
HTQFVAVTSETSPLANNPQYLASFYMDDFIGGRYSSSSVCGAVVLTLAFGPQVFGHFLSGAAEADRAAQEQDIRRNAALL
DALIGVYERTILGYEHTAVLPYSQALARFPAHLQQLDMESNGKSVNRFGIPITYKTGPVIFGEPGTNGQHSFYQHLHQGT
SVVPLQFIAFQHSQLGQDPIIRGSTGQQKLLANVVAQIVAFARGKEHADANKTFSGERPSSLLYAKALTPQTLGALLAHF
ENKIMFQGFAWNLNSFDQEGVQLGKTLAQHILAGEVEGVLRAYADLFDLAHAPTC
>SEQF2545_AGK84121.1 acetate kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIILTLNCGSSSVKYQVYNWTERAVIAVGVVERVTQAGSVITHEVHGRENHVRESPCPTHTEAVQLIISTLTDAHVGVIS
DMSLIKAVGHRVLHAADRFVKSVVVTPDVLETFRSVQDLGPLHNPANIRGIEAAQAVIPSVPHCAIMDTAWHQTMPEASF
MYAVPRQWYEEYAVRRYGFHGTSFLYTAKRASVILKKRAEDTNIIIAHIGNGASMCCVKNGVSFDTSMGITPLEGLIMGT
RCGDCDPALAFYIMRKTGMSVSDIDTTLNKQSGLLGITGKYVDRRDVCAAMKNGDALARLAFDMEVHRIRKYFGAYVAAL
GKQPDALVFTAGVGEMCCDVRAAACAGLEHLGIRLDARKNELARTRNAETEISTDDSPVRILVIPTDEELVMTEDTYALM
QGTYDVHTRFTYSFQDPTYVNKARAAGLKRDLEKNPALATIVVPRLDT
>SEQF2545_AGK84122.1 6-phosphogluconolactonase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKHIFEDARAIAAFLVSVFDSRLKTQEILWLALSGGSTPREIFRTWAHEFRHHLDWKRLRFFWSDERCVPPTDAQSNFN
MTHSALLEPLEINPDAVFRVRGEDAPESACAAYSQEIEARLPRQRGVPCFDIILLGMGADGHTASIFPHEIELWDHSGCC
VVATHPDTGQKRVSFTGHLINNAHEIYVVVTGREKQDMLASVASDPHASVPVARVDTAKAQWLLDTAAAGAISA
>SEQF2545_AGK84123.1 glucose-6-phosphate 1-dehydrogenase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGKISGSGTVAPHILVIFGASGDLAARKLIPSLWDLFEQELLPRTFGILGAGRTALSTESFRARLAEAVTKHAVRTPHDP
ARLTEFLQKIHYFSFDPTDSVAFADFATYVRTLDQSLHTEGNFIFYLATPPSLYETIPTQLAMHHLNREQGNFRRVVIEK
PFGYNLETAQHLNASLRAHFQENQTYRIDHYLGKETVQNILVTRFANPLFEPTWNRTHIDYVEITASESLGVENRGGYYD
QSGALRDMIQNHLLLLLGIIAMEAPAVVSSSRLRDEIVKVFDCLRPMGERDVMQHTVRAQYVAGKIRGVAVPGYLEESGV
DPRSCTETFAALKCYIDNWRWMDVPFYLRTGKRLPTGVTEVIVHYRTLPIALFEHIERPCAREGNALVIRIQPDEGIQLK
IDLKEPGAGFKTIPVSVDFQYSALTYSHLPSAYERLLLDCMNGDNTLYHRDDAVESAWRFIDPILAAWKSNKSPLLTYPA
GSWGPKAADDLIKGSAPRWHHPSSTLLSDDFACRL
>SEQF2545_AGK84124.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTLSHPTREDRPSRRVLQLGLDRMGIQWHTARGGVRARCVVRVGSLLAALGMGAGVFAAEVFVSPKVGQVGAHPWGKEPA
PRTDVLLYTPTLGLAVGVIAHNGFAFTTELDAGLAFLMFRAQFLVGWAIRSGKNFAFIPSLGVDILSTQDDKLVGIPINL
DFLIFFTKHVGLDFTFGSGVNVPLTKNLKKGANGNGQDLTWSNIWAKYCCTSLVMVKIGPVFRI
>SEQF2545_AGK84125.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRALFSLFRSLHANTHPADLAHAAALALALALLPRSSLLWYLLFAVCFFIRLNRGLLLLSLVLFGFVVPSFDPWLDSLG
NWALCLPRLQPVYRALIEIPFVGLARFYNTMIAGGLVAGALCYLPCYALARCAVTAYRTYLYPKIHHATIFFLVRNAPLC
KR
>SEQF2545_AGK84126.1 hypothetical protein TPFB_0481 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSDDSTPKTPSRRIRHTGRRRTLHRFFCKRYTPRSLKRFLRRIHIPADRAYCMRYLADPVSTPVRVFGRTLLSRTYVRFD
QQAIAHSADLKRLNAIAASIAKQRGRVNFWSLSMACASVLALLGLVYLIRNVIARRVVIGGSEAVFGARCEAAVVDLDLF
NARFRLKNYAVANKHHPMWNLFEIENIDIHFDLLELSRGKFVSHTMVVEGVTWNTPRKTSGALPPRRAKRQRVRSSNPLI
AKIQEKAAELAAPVSFGAGFSALKAQVDPRILLEREVKALKTPTLVQHVGAQAPKLAERWTQRVFDAHARAEKTVAAIRA
VTELDFHALKDVSAIKQGIETLDRARRSTEEALATARTISHELQQDVHSTLGLAREFAAAVKADGARIARAAAAIRDIQA
DGGKKFISGLCTVFLARSFSHYYPYVAQMLDYVRGSQRTPSDGSPSAEAEKTAQSLTTRKRLAGSNFLFERNVPSVLLRN
IGVSAADPQARFSVAARVRNASNDAHGFGESISFLLDVAAGAQDASLRGVVDLRRAHPDLVDVSCTARGIPLAVPAPAEG
FPELSGVLGLHTQVFVRKDHSVELKMGARISDSVLRAAPFEPRVLFDVYADVLRQIRQIAFEATVRVSAEGALSISVESD
ADGAFVRALSRAFAQQVDALRRAVIAEGERFLAQQRRVYAQEIAQVTQLVSRAEDAIAQLGVSSRVIQQKRAEAERLLEA
AARKALGEVTKRAADELQNKARDAFRSFF
>SEQF2545_AGK84127.1 hypothetical protein TPFB_0483 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNLQVHRWCARSPYGCLNLKVRAQKKLSIMSIISRVCIPCAVLLFAQLHAKELVHVSQLKEQEARISWQEVPGAVSYRVL
IRNAHGRIVTNAVATTRSYSFSRLRPGSYQYQIIAYDVLHRASASAWTSLSIEKVHKPKTGGITPSTIEHVVGGEAYTVV
LDRSWTYEKGWTIALFPDDKADEAGAYVKPLSVSKNKEGNWMVAIPNAALKTGSYTLRAITPRNIYAEVRGILHVVLWRR
PIFFYYDLSVGYAPVYRPQDHAATINGVSDFFKICSPIGFVGTFEMCFFKRNSSTISAGFNAQMHSDSKQVDVKLDGNFA
YLYELYPRIEVGGMLGLGYSLPFGQRKEDDSMYSYVTGTMKYFFTNSIYLRVQQQHMLTVNKGFSKVSLQQTPSLSFGYR
FHN
>SEQF2545_AGK84128.1 hypothetical protein TPFB_0484 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLRTTTGSEAVIVFTDNSRLDIAENTMVRISHTGMKKKDVRLVTGAIRYARAAGNPAAHTVHVGKTTISLSGDGQVNVRG
GERDSTVEIARGEALLHDAQGQTLPLQTFTQLATSREDGTVRILHPTFVPLLPDQDALLLTAEHTRSVGFVWLGDATTVQ
PSVRLQISRYADFSVIETERKLTLPHEANASRTTFKTSERLGEGRWFWRLVPRNGTASAPRSFSVRRARKVMLHTPRAQA
VLSYRDAIPPTLFSWTSVEDVEQYRLLLSSRADFSADVKTFSLRTPEISVPGLGEGTYFWKVVPRFDEGIEDPVFASEVG
TFSIKQGKELHAPVALFPAEDEVLEHADRENRMVIFTCEPIPEARRYVWTVKNMDANASPLVTTTSVPFLTVPMRSLRAR
LQEGTYQWQVAWETRRSDRSPYSALRAFTVIEGMHAWEEEPETRDLIALRAPSFVLRDMPALITEKYLLQHRALRCKWTA
VHNAQRYTVTLKNKKTDAVLQTATTTGVEFSFTNLAHLEEGSFHWVIQAHTEQKGYEPASAQVVRAFTIRVSELESPRAK
EIVHYEYH
>SEQF2545_AGK84129.1 putative adenylate cyclase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRKNANQKIVWPLTTKLIGIISTVVVLATIAVTAMASWFFASSLHSNAELNNLAAAENFAAQIKGEFEAIATSAKSFVS
LGLRSGARMHSRSALSKDFFSFYPRIGYIGVGGVAELWNGDFFKKNQLRVADARRFLADNAQVISTLQTAPATLNAAPWF
KAQIIAIVAPFEVDGATRNVVVIFSADVVQHLLESGASSGTMYAVTWAGNSLYHPEYSLNYSNINLQDSPVVRDLRESTQ
LTKQISFIGTDNKRYFGAFAKQTFGKFAIVLETPMSVVYQAVYYAIILDGILTGMVLLASILLVWFIAQSITRPILTLVG
ATHAISSGQFLLDIKPSSKDEIGLLTETFVSMGRGLAERERMKEAFGKFVNRDIAEKAMKGELALGGERKTATIFFSDVR
SFTEMSEKLPPEDVVEFLNEYMSCMVDCIEQTGGVVDKFIGDAIMAIWGAPVSLGSARLDALQSMKAVFLMRESLIQLNE
KRVACSKPRIGIGCGVNTGSCVAGQIGSSKRMEYTVIGDAVNTASRIEALNKPFGTDFLISENTYELVKDMLIVEKMPPI
TVKGKREPLNVYAAINLKGHDGPQTLDELRALLSIEKPGLSADPDFEEKKCEVI
>SEQF2545_AGK84130.1 hypothetical protein TPFB_0486 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKNVLPMCAVLGAGCLFALEVDRRELERANATVEFENFAGTHTDVDSAAAIRRIGEGLASALRGGVAGDRARYALIHAVG
PHTTNGFDADILIIGAQARVDHIDNIREIVAAYLSAAYGYRLQDARTIATFTTVYNAVYRADLPTFKARYKGVVTAHLSP
EHVGIARRFDQWPGKTQLVIPLSGHSDALSAVDTGAISDKRVVERLREDPDKNVDLRKDMIDLKEREAQEGTRRAQQLAQ
QSQQAQERAAELSTQAQRAQAHADKTRREAQQAQQAAQNSPDPARTQEAKEKERVAERAQQEAQQAAHTAQKATEQAESL
AREARSQEQRAQQKSAEAQRERLEVAGDMQRMMNAGRAKATHGAQEARESVTPCYGLKVVDAQHLLSEIVLVDPKTEAPL
RSSSLRTVRNRLLYSEPHALVAIADTTGNGTVRLVHIDPKTLEVTKESTQRIAAQSFLLREEEHYYAVIDENGSHFLGRF
TKNLELTTRSAAQVTPYTAVTVTPRGIMVQTKEKGMALLHTRTLADALPRT
>SEQF2545_AGK84131.1 hypothetical protein TPFB_0487 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRHKTLHPARADSTTGVLSFARFYGKKLRPTGRVGSAQAHMQRIRRRTLGASPVRPYTKLATEATTVGKRIHTLPQRDQ
NQYRAERVRIPVRYRALTVFLAFCLADPCAARSGAAHAGNKDPSWSVVLAGQNVTQPVRYDSLIYTFSADRALNCVNSKG
SFVWRRNCPVVGTPFLSVSDDGLVYVSEVSGRVWVFSSQGIPVREFAVLPAATRGAKRAVNAANGGLCTAPVILRDGRLL
YTTAHALLCFSSTGQRLWSQKLGAKPLLPPTDAKTREFFITGPQGTVEYWSIFGEKKGALRASGSVRALTSTPRGYVVAT
DQGLWRVRTDTLNSTPDKTQAGKTAKQHQAPVPVRISTQRSCVALFATENMLIALFADGAVRAYDADGENELFSLTLPCT
FSSAAQCRVQGDEIVLSDTARAITLSAGGALKWNISLYETPFTPLITTDGLVVSAGGWVLNAYRAETRLIDHTPIYNRDS
YFHVLGSSRRAHVQEAPPSRPAAPAKRSPYDSIFSSDPFFSSPAPAKNSGKTDNAQETHTTSPPGPYATPELLLQAVQTS
LKEGNVGPREPAYARSLHALLTSPHHARARAPAVTSARRAQAATLLGALGAHEYRDALLELLKEQDYTVLEGILKGLTRC
TFGLDERALLALYRVTRAKDARAESLMRAACDALAACARSAPRTLSEKAVSELSRISTGAFPYTIRAYARTLVQSMLR
>SEQF2545_AGK84132.1 methyl-accepting chemotaxis protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCGATACGARICKAERQEHCEGAVPYGYAHPFCTVLVLISLREGVYPFTHCGCLRSELCVGSNGRCPKRAAPDALHMCLR
GAHAPCGAELFPVKPCKRKNACGRIGPRWVKGLVTFHSHIIIPREWLMGYGSSAEETSSTPHASGQRKVGFLSLRTKLAL
VFGLLAFVSGLVQGSILVVFARNSIIREISSHLTDRARDTCSIVEGQIGALFQFLEGLARLEVLQGSSDGRRAQVDRLKK
EAFFNRDITRLAVVDLAGVLYGEDGRTHYVQDRKYFQQAVKGRRYVSAPYRSRLSGDMVITFSIPVYNEDRRIIAVLAAD
VIWTWLCDITGDFSVGETGKSAIFDEVGTVVAHPRHEVVAQQANYIRLAKEDPATYASVAEFVEEVIKSDSIASRTFSHE
GSEKIGSYAKMKSTGWTVVVFAPVSEFMGPVYTLQNYLLAVGIIVVLFSLIVVYAVARKIVRPLRSTVRVLEDIAYGEGD
LTVRLPVVGGDEVSLLCQYFNQTMEKIRFAIATVGSSSDDMRRIGDELASNMTETASAVNEITANIDGVKHQVDLQVSGV
SEATDTVERIIKTIKGLNSSIETQAVNVAQSSSSVEQMVANIVSITQTLERSDEAVHSLAIATADGRDTLVSSSGITQKI
SEESGSLLEASSVIQHIASQTNLLAMNAAIEAAHAGEAGKGFAVVADEIRKLAEESSTQGKTITETLKTLSVEIDTLSTS
SKAVEEQFDTIFRLSGQVRTMSRSLTEAMKEQSDGSREVLAAIKSINAATVDVKEGSADMLKGGEVIAREMQRLDDLTSE
IARSMNEMAAGAIEINNAVHEVNEITQRSKQSISSLADEVEKFKV
>SEQF2545_AGK84133.1 metallo-beta-lactamase superfamily domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRVHFWGVRGSVPTPVTPRQVQSKIAAVVQRISAKDVRNQRSKERFISDLPAWLFGTTGGNTTCVEMETDCGETLIFDAG
TGIRDLGIDLMSRPGYRAQGHVYHLLFTHFHWDHIQGLPFFNPAFDPRNTIIVYSTRKKMKEFLEDQMRYPYFPISMFGR
DGFNAKFEFRLIGNHEECFAIGKTKITWNRVRHPGGCVSYAVSEAGGKKVIFSTDTELRQKDFDRSERNVCFYDAASLLI
IDSQYTMTESIKKEGWGHSTFSIVVDFAVSWGVRRLALFHHEPTYDDKKLFSILQNACWYRKYVGAHDLEILLAQEGKDI
FV
>SEQF2545_AGK84134.1 hypothetical protein TPFB_0490 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSEEERMYSFSGEEIKELALLFRRCGQTLAPALRRLALFVDRTVCRHMTVEEAEDFFGSAER
>SEQF2545_AGK84135.1 hypothetical protein TPFB_0491 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSIRTFSFTPSVRLRRIVLWGSLFCAGVLCLLCLCLLVGLAPVRPFVKKEHMFTVQSGVGARKVIHELRNARLIRSEWAA
RLYVFARALNFKAGSYAVSPAMSAVRILTMLDDVEQQRFIKVTVPEGLTVKKIAALLQDATVVSAAAFVEACTSAALRTR
YKIPAPSVEGFLYPDTYFFSYQERAANVVGTMIENFLAKTSQLPSFPGDPVARFKTVILASIVEREYRVASEAARIAGVF
YNRMKVNMGLQSCATVEYVITEIEGKAHPERLFFKDLEIDSPFNTYKCAGLPPAPISNPGLTALNAALHPEVHDFFYFRL
TDPQAGTHTFTKTLDEHDQAGLMLLKKNTGM
>SEQF2545_AGK84136.1 DNA primase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARISAHVIDAIADRVDLVSLVGNYTHLERRGDDWWGRCPFHHERTPSFHVVPDKKMYYCFGCGVGGSTIKFFMEIEKID
FHEAAVRLAKRAGIEMSFEDGVHAPSAHASFTMQLCEVYQRIAETFHHVLMHTAQGARARAYLASRKVTDDSIRTFKLGY
APPDPVWLFQFLRHKGYSPEFLARSGLFAKKSERIAVFSDRIMYPIADRYGQVIAFGARALGTAPAKYLNTADMPQYKKG
EHLFAFHCALSQMRKTRAAIICEGYMDVIAFHQAQLTYAVAPLGALLTKSQARLMRSFVDRIYMCFDADGAGRAATYKAI
LLCRSLGFEVRIVELNGGTDPAECACIEGEDALRKSVERSTTDAQYLIRCARHEHSHLGADDTSRAVSFLFPYLSVLDSA
IQREQVMQDIAMAFGIRIQAVHADYLRYVSRTTQKGTTGNCVLSVQGTAIQVKEPATGVRTAQLRLVLAVVANLELFELL
RESVCADDFEDPMAKELFIILEECYRADTRASPHVLSCCTTDELRKLVSEAIVCGEFSCNAPQIVRDGVALVRRNRLLKE
RESLVGRLRRFGDASSGEECGSMQELMMEKQRVDEELERLKGVRK
>SEQF2545_AGK84137.1 DNA-directed RNA polymerase sigma subunit RpoD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMELSRTPAVMRLLEYAREKKAITHDEVENILAHYGVETEELLHDVLDMLEQENIKVFSSEEEELEDEVFAGLKGPAADD
GDGSFPLSTERVRDKLCDSSRGARQNLLSNARNIALDDPVKLYLRDIGQEKLLTAEQEVMLSKRMEEGEGIIKDIITQSG
LLLPEFYHIGRSLSKKALAVLDPAESGRTRKEISEEMADRRRLKQAYGEVLRSLYPEMRHYMAMKKRLDERGEPVTVLSS
DEEVCKQRDKLLSCLQKVDLQLEEIDRFSRKFLDTARKIREYKRRKDRHEKQLMIADLCDMRKIGRGLAVPRQRAKLEET
LGMSADCIQEIYTQIQKVTRRLRRIEYDFENTIDGILSMARAIHRGHVMLKKAKDKLINANLRLVVSIAKKYTNRGLLFF
DLVQEGNIGLIKAVEKFEYRKGYKFSTYATWWIRQAITRSISDQARTIRVPVHMIEQINKVTRESRQLLQKFGREPSDEE
IAQQLCWTVEKVKQVKSVAREPISLETPIGEEEDSSLGDFVPDADVENPSRVTERVLLKEEVRSILSALPAREHEVLRMR
FGLDGDYSQTLEEVGLYFDVTRERIRQIEAKALKRLRHPRHSRRLKDFLDS
>SEQF2545_AGK84138.1 hypothetical protein TPFB_0494 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVPANVFENLRALQVVLAQKNRLETEIAEAPKFLVAQEELLTRCKESFIEKNVEYESVREEVARLTTELCKAEKRREDAE
VAMDNISTQREYDALDREIQEAKRQEVALRSEVARSDVAYKRLAEEIKLDQEDIVQQERELTENKARVDAEVRGKREQVL
RLQEEERRLSPDLDRDVLFKFERIIKSKQGVGIVPVRGNVCAGCHMILPAQFSTGVREGNSIVYCPYCSRILYYEETDEP
EMTFFDEEDLGSLSDLVYPEESGGFGGGDREEI
>SEQF2545_AGK84139.1 hypothetical protein TPFB_0494a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRTWAVCRTLSIQKNLEDLGEVTGKRYREVGKWGDRELQIVAAGFSQRKVRTPSEMMLVNY
>SEQF2545_AGK84140.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTESGLPVLCFFRVSMEFLLRRSGHQSFFPGRRKLPNSVFLFSVFFALVVGVGFGAWRYRRYYRGLPSARSVYEDWKNGN
YKAVYDKAAEILQRRVFDAEMLALHGFAAYYIFSEQTDLSVSYDYLNSAIVSLRRALHVVRPAEVPNVSYVLGKAYYQRG
YYYADLAVKYLDLAYNAGFRAADLAEFRGMSASLLGDMQKAVESFTQALAAQPSDLVLYALAECYEKLSDFSKAKLYLYD
TIGKTKDVLLELKCRNRLAALYLSERNLAEAERELDVVLQKDERSAEAHYHRGVLYEMGSDLVRARAEWRRALRLNPLHE
PTRVKLNLK
>SEQF2545_AGK84141.1 cell shape determining protein MreB [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFFLRRFSADVGIDLGTCNTIIYVEGRGIVVNEPSVVAVERGTKSVVAVGSDAKRMLWKTPGNIVAIRPLKDGVIADMDT
TEKMIRYFISKILPRHRLIKPRMVIGIPSCITDVECRAVHESASKAGAGEVEVLEESLAAAIGANIPIEEPAGNMVCDIG
GGTTEVSVISLLGMVVTNAIRVGGDEFDQAIIKHVRSVHNLIIGEQTAERLKIEIGNASPEKNIEKVEVKGTDAITGLPR
RLEIDSVEVREALKEPITQIVEEIKRTLARTPPELAADIVERGIVMTGGGSLLKGLPKLISKETHVPVILAENPMNCVAI
GAGRYHEVYKDISGDRSLYAGLNS
>SEQF2545_AGK84142.1 cell shape determining protein MreC [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEKAFFFRIDSDLFTFIVFLLVSSGLLVFSGGELIVSFRDVGFSVTSRVEKAAASVSFFVTHTVKTLKTLSEVQRRYEVL
REQLKDYEFLQGSRESLRKENQRLRAMLGFSRELSTRNIPAEIIGFDPDNLYSGIVVSRGARHGVRKNMPVVAFQSDTLG
LVGKVVQVSRTTSMIVPLYHYQFYVAGKLERAQYRGLISGQGGSDFPLLMRYVKKHGQGSIRVGDLVVTSGENYPFPKDV
PVGKVRDIKLHDHETSLELSLDPVLDLFRLEYVFILDLSLSQEGPHG
>SEQF2545_AGK84143.1 cell shape determining protein MreD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRLIAWSVGTSFLFSIVEMAVFVHVSYLSIMPDLVLLVVLFTSIHNGVVAGIWTGFIAGIIFDFLSISPFGLHSFVFTT
IGFMVGKVQGRYHIDRVFAPAVLAGFAMIFKVGLVLVLRGVFGPNIQVYSVFSRQLWIEMTLNIVFVPFVFGLLNMFPTT
FLYKRFSS
>SEQF2545_AGK84144.1 penicillin-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRYFSLLPDRHMLFRIKVLTWLVVLVMLLYMRQLFVIQIVRGDSFKKKSLNISQRSKVIPAQRGEIFDRHADLPMVLNVN
SFAVDMIPGEVPPEQFDTVLNKLSHILRVPISDIRKKIPDAVRRSFQTVELRSNVSYEDITAIAQIIDELPGVSWYSKPV
RNYVETGSFAHVIGYVGEITKEELKRFYSKGYRPNSLIGKAGIEKEYDEVLRGKEGHEYRTVDARGRYIENTSVTNPPRM
GNNLVLTIDRRIQKLAEDALGPRIGAAVVLKPTTGEVLAMVSYPYFDQNIFTQHNAHELYAQLSHDTRFPLLNRVVNASY
PPASTFKIVMSTAILAEKAFPHEKTVDCPGEIEYGNRLFRCHIRKPGHGKVDLRRALEQSCDIYYWTVCRDYLGIDRMIS
YINDFGFGKSARIDLPSQTEGMVPTPKWKERRFHEKWLDGDTMNLAIGQGYMLVSPLQVANMVAMTVNNGVIYRPHLLKE
IRDSRTNEVLFRHKPEVLKTAKIPAEIFEHVRADMHSVVTRGSSQYAMKNKTVSLAGKTGTAEVGFHNRWHSWMAAYGPY
HRPPDEAVVVVVLVEARNEWEWWAPFATNIIFQGIFANEDYEQAVESLKSYGISLGVPARSRQE
>SEQF2545_AGK84145.1 cell shape determining protein RodA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRIRGVSDFDYLLLLTMLALTSIGILFIYSSGVNSEGHVISREYLKQIVWAVMGVVLMLSVSMYDYHRFKDRTTLIFAGF
ILLLIYTRLFGRYVNGAKSWIGVGEFGIQISEFAKIAYILYLAHYLVYSQSEPMLKRFAKAGVITLLPMALILSQPDLGT
ASVYLPIFLVMCFIAGFPLRLIFAVVCVVLLTLLFTLLPLWEQTFLQYQGVATRIADSRMLSLFVFFSLSATSAVAVVGY
LLSGRKYYYWITYALGMVSISYGASLLGVRVLKPYQMMRLIIFLNPEVDPLKAGWHIIQSMIAIGSGGAFGMGYLRGPQS
HYRFLPQQSTDFIFSILSEEWGFVGGVIVFGLYLLFFLHTLSIMSHVDDLYGKLIASGVLGMFLFHFVVNVGMTMGIMPI
TGIPLLLLSYGGSSLWTAMIATGLLMSINARQL
>SEQF2545_AGK84146.1 ankyrin repeat protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKVVLFYDQGRAHSVAAICEVLCAQGCAVTPHAIEQVWNDTSPCSTPLALVQDATHVFFLYAHEPMRDPAFIFFSGVACG
RGMHVLLLATTTEVRDIHVFRDLVFLLEEETFEDFFRVEHERFVRQKKKRVARTALLERGYPCFEENFIATVMDGNIDIV
NLFLDAGFSAALKDARGTPVLSLAVREGQDEMAAQLIARGAPVDQLSDDRAYSALMEAAQIGNRTVARLLLHAGADPNVR
GSNGQTALVLAVGRKDHVLIRLLMDHGANPYLEDKLGLSAQGYAKLFNDPTLCTLVGV
>SEQF2545_AGK84147.1 hypothetical protein TPFB_0503 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYAGGRVVRSAFARGKVCYLIGSVLWGSVSCTQPRVQKWVQNDGKVNVHSPQERAGVVATFGTVRITRSDYERTKAELQD
VVAHLNRITAERDYHKWLVYLSDAYRRAYSMPDILQQSSDALPKKGVRLRHLRDYFIHVFVPSRQNVRVDSIVFESPTRV
DVIMNHGGKALLVYKIEKIHSAWKLLP
>SEQF2545_AGK84148.1 hexokinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDQHTRTRDLVSAFFGRFHFDVQGPSVRTVVDVLRADMVRGLEEEAQLPPRMGSALAMIPTWVAPPRVSPCNRRVIVIDA
GGTNFRSCLVRFGDSGTPHIENLEKRPMPGTTREYSRTEFFGEIADNLARLKGAADCIGFCFSYPIRIRPDGDGEVIQFA
KEIKAAEVIGTCVGAGLTEALSARNWPELRSLKMLNDATSALLAGFFAAPEGCSFSSYVGFILGTGMNSAYLEPDPIPKI
PAHHTPQVVVCESGKSNKVPRSVFDELFTQTTAEPDIAHLEKMSSGTYLGPLASVVVRLAAQEGLFSHAVHAALSTVSFT
LVDMDRFLFAPSVSTTTLGALLAPGTDTDREILFLLLDAVVARAARIAAGVIAASVLKSGAGYDPLRPVCVLAEGTTFQR
TYRLRTRVTSHLQAFLTEERGVYFDIISLENAVTLGSALGGLSS
>SEQF2545_AGK84149.1 hypothetical protein TPFB_0505a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLIHTRPPWSAARVARIARLGNRSCKKGVPAYGAGSLYLKTGPMRNEYGKRSVPCRVNPTDPVTAQSIPYYAPVVFGDLD
IFLEVWTD
>SEQF2545_AGK84150.1 peptidylprolyl isomerase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MELQKKFTALAQSQVELEVVVAREDAQRHYQRFVEEYLERARLPGFRKGKVPLAVLERKYGSAIRQDAAAALMEKALEEG
FAQASQDSQPLPISRPSLKKKPVFDPDEDFSFAVIYDVFPSVELRNTSGFSLSVPTVSVTEEDVSRELTRIQERNALVTD
KGADSCAEVGDIATVDYHEVYDSGAVRPGTERAGVVFTLGVEEGPFALGQDILGMKLGQRCLFAKRAGMLKDEAAQVRVT
LKALKQRQLPSLDDELAQDVSDAFRTLDDLTRSVRQNLAEALEAALHEYKRRQLLRILVRENPFSLPESLVVGEMESRWA
LVMRQFGVSLSGAPQNKLQFFQQWRPEVEEHLKQRVIVELLLKQEQVSVSAEEFETEYVRIASKTGSKEERVREYYAGEE
KRRALCEGIRERKLCQKLLGRCVTECGPEQSLTDFLQEQSRA
>SEQF2545_AGK84151.1 S14 family endopeptidase ClpP [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRERMHNLVPYVIEQSGGGERSYDIFSRLLKDRIIFVDGEITDAVADLVVAQLLFLESQNPDKDISLYINSPGGAVTAGL
AVYDTMQHICPEVQTICLGQASSMAAVLLAGGAPGKRFALPSSRVMIHQPWGGVQGQASDVCIQAQEILRLKTLTIAYFA
LHTGQSEEQVREDMERDFFLSAEQACSYGIVDTVMKRRKHAQV
>SEQF2545_AGK84152.1 S14 family endopeptidase ClpX [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLRSKGDLVLGCSFCGKKEDERRRIVTGHGVSICNYCVERCAEYLRDRKPSALALMTKEEIPTPLELKAYLDQYVIGQDL
AKRVLSVAVYNHYKRVAGRSLDIDSVLIEKSNVLLIGPTGSGKTLLAKTLSQKMKVPFAIADATTLTEAGYVGEDVENIL
LKLVQNANGDVALAERGIIFIDEIDKISRKSENVSITRDVSGEGVQQALLKIIEGTIASVPPQGGRKHPNQDMLRVDTSN
ILFICGGAFVGLDGIVGTRVCKNPVGFGADVKTVKERGLQLMHEDVIPDDLVKFGLIPEIIGRLPVTVALDALSKEDLRN
ILVRPRNAIVRQFEALFALDDVRLVFDEDALDAIAQQAIDQKTGARGLRSIVERLMLDAMFEAPSLKGKKELCITKKVVT
QEEKASVRLVSERTA
>SEQF2545_AGK84153.1 peroxiredoxin [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MESLIGKRVIDFKLPAYVGGKFTEVSNASIKGSWAVFMFYPADFTFVCPTELADLARVYPSFVEIGCKVYSVSTDSEYVH
KAWADATDTIKNLPYEMISDKAGKLAGFFGVLLPDTWHALRGTFVVDPEGLVKAFEVHDMGIGRDADELLRKVQSAQFVA
KHGDQVCPARWKPGAKTLKPGIDLIGKI
>SEQF2545_AGK84154.1 GTP-binding protein LepA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRAMACVRRVRNFCIVAHIDHGKSTLADRLIERTRAVEERLQRAQMTDNMELERERGITIKSHAVCIPYTDAHGTEYVLN
FVDTPGHADFAYEVSRAIAACEGALLVVDATQGVESQTISNLYLVLEHNLEIIPVINKIDLPTADVPRVLQQVEHDLGLD
PASSVLISAKTGENVDALFDAIITRIPPPQGSGTAALQALVFDCHYDQYRGVVVHIRVFEGQVTSGMVIRFMSNGAEYRV
EETGVFVFNLIAREALCAGDVGYLSANVKTVSDVQVGDTITDASCPCDTPRAGFRRVKPVVFSSVYPVDTDECEQLREAL
ERLALNDASISWERDSSLALGHGFRCGFLGLLHLEVVQQRLEREFNQTVIFTAPQVQYYVFLKTGQRIVCDNPAHYPLEQ
EIAQVHEPYIRATIITPTEVLGAVMTLCIEKRAYQTAVNYLDQKRVELVYEMPLAEILFGFYDRLKSISHGYASFDYELI
ESKLTDLVKVDILINGKPVDALAQLCYRPHARRRAQAVCARLKEEISRQQFKIAIQGSIGGQIISRETVSPFRKDVLAKC
YGGDITRKRKLLEKQKEGKKRMKMVGDVEIPQTAFLSVLKEASDA
>SEQF2545_AGK84155.1 CarD family transcriptional regulator [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVNVRDNTEISHSAHASHGAHSSTKGCASLHVLCVMATRAWWSSLVFPLPLPTDFFPCLCYAGPMGKACAFRPHDHVVYP
GQGVGQVQEISEKTFKNETLLYYVIYLEESDMTVLIPVDKAQELGIRTIVKRKEAERALRFLSEDFDPSPLDWKMRYQVN
LNLFKSGGILDNAAVVRSLYHRSKVKELPIQERRLYDSAYRIFQDEMCFALGLRPPEVETLIHGYLEKAKENPVVSGTVD
VPG
>SEQF2545_AGK84156.1 bifunctional 2-C-methyl-D-erythritol 4-phosphatecytidylyltransferase/2-C-methyl-D-erythritol2,4-cyclodiphosphate synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTRAALLVTAAGSSARMRRGGACVQKKEYLPLTSRQPGVCLLSEILVRALEARSFFLVVVTVPAGEVAYAESQVACDSRL
SAFPSRTRPVILYVPGAHTRSASVRAGLDAMATHAPDVVLVHDGARPFVSVALIHSVLEATCRYGAAVPVIEATDTPKGV
AADGSIETHLIRSRVRLAQTPQGFCYASLCAAHHRAATDGEQYTDDSELYARYGGTVHVCAGERSNVKITYPEDLEQRAS
EPALTRGISVLPCTEEGALRVGLGTDMHALCAGRPLILAGIHIPSKKGAQGHSDADVLAHASIDALLGAAGLGDIGTFFP
SCDGRWKDAHSCALLRHTWQLVRAACWRLVNLDAVVCLEQPALHPFREAMRASLAQALDTHVTRVFVKAKTAERLGPVGS
GAAVTAQVVVLLKKV
>SEQF2545_AGK84157.1 Trk family potassium (K+) transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRVIVVGCGTNGRELTRRLSARGHQVTLVAAAHEPVPRKIPAGAQALVRHQKDHRATLGEAGIAKAQAFVAVTEVDELNI
VLCGIAADLNAGVIKIAQTHDDHYAHAVCRESRCIFGIDFLISADKEAMRAVVSTVEQGAISDVIPLKNAPYEIARFPIA
KGSGLDGITLSDMRRLVKISFVAVAFEVRGRSVIPSGETMLASGMRLSVLCAPEHMGRFYELAGFKIHPVKKIALIGMSA
VGTLVAQDVAEKCKPHFFSSAFSLSPRERASLVLVDKSETATQAVCAQFPHVTAYHGDVTDEAFFAEITPDTFDLVITTT
NNYELNMITAAYMKTLGVPRAVALVHSSLMEDIAGKIGIDVAVSYQDVVVDAIMSHLAGSHVTGIHTIGDGSLEIVEFAI
SAQSPLVGKRLKDIAVHGSFLVLLISTVRGSFIPSGDTVLLEGSVLMFIVQSAQSEKIVALLGGTV
>SEQF2545_AGK84158.1 excision endonuclease subunit UvrA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGSAARNLCIKGAREHNLKNIDVMLPRDALVVISGLSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGRLDKPDVDSI
EGLSPAIAIEQKTTQRNPRSTVGTVTEIYDYYRLLFARIGRAHCPHCAREIKEQTVDQIVDTLMTVPSGSRIQLLAPVVR
GKKGTHHKVLEAARKDGFVRARIDGALLHLHERISLDKQKKHSIDIVVDRIQLSDTVRKRLTESVETTLGYADGLLTVLV
QGENSGTVSGKIETSALLPSELFFSQKNACAHCNVSVPELQPRLFSFNAPFGACPSCAGLGIMQTFDLDRIVPDQNRSFN
EGAFLPFKPEHEWNRVRFAALAEKYHFSLDDPVRNLSKHALDIILHGSGSEALEFSHERKDGSRTARYIKPWPGIFSELH
RRYAESCTHSQREVYERYLSVRTCEACRGMRLKPESLAVTIEKKNIHALSALSVDDSCEFFKTLHLTEVEATIAQQILKE
ITDRLEFLQNVGLGYLTLERAAATLSGGEAQRIRLATQIGSRLTGVLYILDEPSIGLHQRDNERLIQTLLHLRDLGNTVL
VVEHDEQTLRVADYIVDLGPGAGVHGGYVVAAGSPPEVMQVQASLTGQYLAGAITLPIPAVRRTGNGNVLTVHDVHEHNL
QHISVRIRLGTFTCITGVSGSGKSTLLIDVLYPALYNRVMNGRLPEGKFSSIEGTEHLDKVIYVDQSPIGRTPRSNPATY
VGVFTDIRMLFSQVPEAKMRGYKPGRFSFNVPGGRCEHCKGDGVITIEMNFLPDVYITCDVCHGTRFNRETLAVFYKGKN
ISHVLDMTIEEARSFFSAVPPIVRKLEALCSVGLGYVRLGQSALTLSGGEAQRVKLALELSKRATGKTLYIFDEPTTGLH
FADIIQLMEVVQRLVDQGNTVVMIEHNMDVIVQADCVIDLGPEGGMHGGTIVAQGSPEAVSQITESRTGWYIKEVLCKKT
>SEQF2545_AGK84159.1 conserved hypothetical outer membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRAWYPIWGIFFLFCPLFGESGLRKLRIIINSAQETTRLSETGQPILESTGRVPLSPFDLQDQLVVFTGNVSISIDDGSV
TATILSDQTVYNTSAQILYSTGNVRYSRTEGETKTIEISGTRFIFELKTLKGLFLDGSLTLPIKGQQVLFVQSPIIHSDA
YTSVILKQATLSTEEDPEQALWSVHTKNIWLLPNNQLAFSHGVLSFGVVPLLYIPFFYYPKDEFIGNPVFGLRSRAGAFI
QTTTYLLGKRPKSAYPPSFGTQSPAQEEAPNYLKISADYYSALGGMAGISTFFQAKDYLPFVRFSAYIGASRTVHQGGNG
AYSIYDTTGQVMWDKSYLFGMQVPFRYYAECALRFHKTPLYVDVHVPIISDPFFSTDFLQRSEDLNWFHLALSPRSLREL
TQSTISSYDWKISASLRPVWLVLHPWLRDFSLDPISFTVHFNSKSDSKKNNSSPERNFFYPHSMESRAGLSFSGTLFSHV
WERQKSQQKESYAPKEIRNPLAYTPADGLSREGSPPEQSPAVSKENSETDSTFDFFMPEFREENERRTGTDHAYVFTRYA
LDYKGKGDIVYDAQFNHGSWDDASKIKWNDLQSQHVTIRGDFSIRSQFQCVNDIIRMSNGIQCTLQRRYPIHGQPPAKQN
GFQNSALVQSSNNLAVYPFSADSFFRESFLGWSITPVLYDSSPPTGKSSLHVRDHSITANAAFSLYGYTQQIRVSVHFAP
GPYAYSIATFLSFPYISATLSARFLDKPQVRAELDFRMPYEITCKQTYVYDIGKSMSDSYEVSLGWKYFSLSYLLKGESG
KAAPSGNNGLSISKLKLTLSHDDFPLTVRFWKRRIKIQGTLSSSLEINFKDLDKSHISFSPLITFSIYKFLDLSINTVIK
NEKLTPYFPTQSSQSPQTKLWDAFVSSLYFWDEMKRSSALFPIRTLNIELAHYLKDWTLRFGYRLHSEPSSSGSRQISPL
VSSISLSINWNPLPMVRTRARKTPGMFEVGI
>SEQF2545_AGK84160.1 integral membrane protein MviN [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKSKSSLLKSGLLLSLLTLVSRVLGLAREVVKSTLMGTSATADAFTVAFMIPNLFRRLFAENAISVAFIPVFTQHYSMPS
SAQVPCSSKTKEFLSAIFTLMSSVTASISLIGILGAPYIVRLFDTDQSLTVSLTRLMFPYLWMISLAAFFQGMLHSIKVF
VPSGCTPIFFNVSVIFSMYFLNVSHMNVAIAAAIGVLIGGCAQALFQLIFVYMHGFRFTLQSPLKAMHDEGVRRIIALLL
PTTVGIATYLLNDLVCTALATSVEIGVAASVQYSLRIQELLLGIFIVSLSSVVLPDLSFHVMRKDWQSFEDLLITAIKIV
MLITIPATFFVLFSSDRIITLVYKNAIFNELSVRMTATIFRWHSVGMLAIALNRVLISAFYAQHNSFAPMIAGTISFVTN
IILATLLFIPLGGKGIAFSLSAASMVQTVFLWMFLKRSWQITIPSLYKTSLYYGVKITLFSVIALVPTWASSFFTAYFFP
GSHKIISHGVPLCVEALIFSCTGCILLLLSRDEFAYKALRSIRFCR
>SEQF2545_AGK84161.1 crossover junction endoribonuclease subunit C [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHAQNVDIAPGSTSTVSIIVGIDPGLESTGYGVIEAGGGSLRCLTYGVIVTQSNQPSAARLRHIFDTLQQVISIYQPQYC
AVETIYFAKNVTSALCVAQARGVVLLAMAQQHISVAEYAPNAIKKAITGIAQAEKRQVQHLVKILLNLKDIPHPDHAADA
LAVAVTHVHCCMSSNYAVGSTRSRGAYVTLYKKGKR
>SEQF2545_AGK84162.1 thiamine pyrophosphokinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRALIITGGEYAPYEFVQYYLPAYDLLIAADSGLDTALQFGLVPDFVIGDMDSVKDNLFIQACDKTRTHLFPRDKDFTD
TELAVTLAHQLGSDDLSIVGGGGGRADHFLYFMRLFAAPLSPRLWLYRHGLGYCFGEGCVTQQLCIGGVDNTSFSFFPVG
DATDYSLSSEGLHWPLDGVPWHTHVSMSNRSSAPVVRVEAHRGRFLLFLSPLGRYTIDHHERGIACTHRT
>SEQF2545_AGK84163.1 sigma-54 dependent response regulator [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKFSILVLDDEKNIREGLQMALEDEGYEVFTAEDGNTGVEIALKGDIDLIITDLKMPRMSGELVLQHVHAVLPDIPIIIL
TGHGTVENAVEAMHKGAYDFLTKPLDLNRLSLLVRRALQNRELIVQHRELIKQIGNRTSFENIVGESPAMNKVFDMVKKA
AASKASVLITGESGVGKELIANAIHNLSPRKAKPLIKVHCASFAEGVLESELFGHERGAFTGAVNRMKGRFELAHEGSMF
LDEIGEVSMAVQIKLLRVLQERSFERVGGRETIKVDVRVISATNRNLLEEIKRNLFREDLYYRLNVVHIHVPALRERKED
LPLLIATFLKEIAEENGKKITSIDPQAQSALHAYDWPGNIRQLRNCIESAVIMSSGPVIHIEDLSEPIRSLGETSSIRIP
IGVSMEDAEKEIILQTLEAQKGNKSKTADVLGIGRKTLYLKLDQYTNTSFEPDAAAKS
>SEQF2545_AGK84164.1 DNA-directed DNA polymerase III gamma and tau subunits [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFENIVGQPATDLLRDDVMHARLPAALLFVGPPASGKLTAALELARVLSCTQGGVWQCPCAPCVQHTELLSPELLVMGIK
DLILEIRASARAYMSVHTQGTRYLFVRAVRKLITRFDERLWDSDDTRFSAAVSSIAELDQELASLPAQGDRRTTPEQKER
VQRICVIAERLQQESLYTQLPVQQIRNAIQWVRLTPSGRKKVLIIEHAHAMHESARTAFLKILEEPPRDTLFILTTATKY
AIMPTVLSRVRSYSFRERSVELQCAVITRVFHDRPTDAKNTQGVLLHYLYQFLSFSLEEVQTSVMYFWLYVCQHARCIGR
IIPDTWVSVGTQPQVSGMDLTSLDSTMHFFQAHKQQHAVSLFFSLLVRHMRTLQRTTEYSARNTECFAHIAHCIEQAHRN
VQLWNLTIQGTLEHLAHTIANHL
>SEQF2545_AGK84165.1 hypothetical protein TPFB_0522 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTISTLDLILGIIMGIVTVRATMRGFVDEFFSKASILCAAVVAILCHKRLVPLTRVLLGHSILLPCITFLITFMGVYCVM
LFLRSRMRTYATRDLISGFNQVFGFFFGIIEGSVLLTVILLLLHVQPFVSVSHMLHESVINTVLSPLVLDGVRYMRLKM
>SEQF2545_AGK84166.1 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRFRARVSQSTAKCVVFTGGGTGGHIFPGIAVFQALAQQAAVRVVWIGAARGADRSIVESAGLEFCGITAGKWRRYASVR
NFFDVFRVLVGTVQSYCILRALRPQALFSKGGFVSVPPCIAAWLLRIPVVTHESDISPGLATRINARFADRILVSYPHTS
CYFPRARRAAVHCTGNPVRQDFFSAQAERAYQFLRIDQKKPLLTVLGGSSGARDLNARVLSCSTFLTERFYLVHQFGAGN
EDQMHTITNSLSVNARHAYMSFPFIQAHLPDILAASALVLSRAGANAVWECAVLGKPMILFPLERGSSRGDQIENAEYFS
AHGAACILRAQDEKGHQLVSLLTELFHPSCARIEEMARASYTLGIGNAAYDIAQQLQTFIKEGM
>SEQF2545_AGK84167.1 S16 family endopeptidase La [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKNTDIEHDAHEPAGHGDVRESAVENPSASAVSDGEERATFAPEVAPQTDTESAQGAAQESEPEVQRAGEAEKGVPEKA
KAVVPLDELLPQKVHLIPLTGRPIYPGIFTPLLISDEDDVRSVESAYSDSGFIGLCLVKTDTQNPTISDLYEVGSVARIV
KKINLPDGGLNVFISTQKRFRIRKHVHHSKPIVAAVQYLSDLIEGDPLEIKALVRGLIGEMKELSENNPLFSEEMRLNMI
NIDHPGKIADFIASILNISKEEQQRTLEILDVRKRMEEVFVYIKKEKDLLEIQRKIQNDLNSRVEKNQREYFLREELRSI
KEELGLTTDPKERDQRKFRALIDSFHFEGEVKEAVESELEKLSLTDPNSPEYSVGRTYLETVLSLPWHAPEKEEYDLKKA
QKLLDEDHYGLENVKERIVEYLAVRKLRADTKGSIILLVGPPGVGKTSVGKSIARAIHKPFFRFSVGGISDEAEIKGHRR
TYIGALPGKVLQGLKIVKTKAPVFMIDEVDKIGSGARGDPAGALLEVLDPEQNTTFRDHYLDLPFDLSHIVFVLTANSTD
PIPRPLLDRAEIIRLSGYIDTEKVEIAKRHLVPKTLEKNGLKRACVSYRKEVLLHLVHSYARESGVRGLEKSLDKLHRKL
ATEIVLGKRSFDDKCLMDEALIGTFLGKPVFRDDMLKDANKVGTAVGLAWTGMGGDTLLVEAITIPGKASFKLTGQMGAV
MKESASIALSWLRRYSAQQRIASPNWFEKRAIHLHIPEGATPKDGPSAGITMTTTLFSLLTQQKVKPRLAMTGELSLTGQ
VLPIGGLKEKTIAARRGGIKEIIMPKANVRDLDEIPEHVKKGMVFHLVESMEEVLSLAFPKGKRVRAGTAAQSASPETLT
G
>SEQF2545_AGK84168.1 elongation factor P [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRGGDIAKGTVLLHKGAPYLVVEREFVNPGKGAAFARVKMKHLRDGSVLTQTVKTSDTVEDAVVDSHRAQYQYDDGECF
VFMDTRSFEQIFVSKGNVPGRERYLREGDEYDILIWNGESIDIKIPTKMVFRVAHSEPYLKGDTVSGATKPVTTETGLVV
RVPLFIKQGEKILINTETNEYQERVND
>SEQF2545_AGK84169.1 hypothetical protein TPFB_0525a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIASSSYCVWIGQDRKKNQKWEWCERAVGSVRTRTARTVLRVQKDGATKR
>SEQF2545_AGK84170.1 ATP-dependent helicase HrpA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFSYKQLPVYSQKDKILSALAHHHVIVVESPTGSGKTTQLPLILHEAGYNEGGAIGVTQPRRIAVLSVSEFIAKQVLHVQ
PGIVGYKMRFEDHTDVETKIKVMTDGILLQEMKLDPLLSKYSIIMVDEAHERSLNIDFILGLLKRVLQQRHDFRIVISSA
TINTAMFSRYFNECPVIKIDAVAYPVTVIFDPPDTPASTHTKEAEAALLEKIVCIVERVIASRDKGAILIFLPGERSIKN
CITRLSHERWFRKLFLLPLYGRLSKEEQEQVFNRAPFGKRKVVIATNIAETSITIDDVTTVIDSGLVKLNSYNPLSYTAS
LDETPISQASCNQRRGRAGRVRAGTCYRLYSRDDFEQREPYTLEEIYRTDLSEVVMRMAELGIHDFEHFDFISPPGTHGI
IGAEDTLRLLGALEDDRSLSEIGKMMCLFPLGPRQSRMIVEALRRYPHSIDDVLIAAAFLSARSPLIFSEDQEEKTKKAH
GTFSDPMGDFVSFLRIYRAYAQENNKHSFCQHFYLDERIMAEISNIKEQLELIVSGMGFPLLTGGTVEEYLICVGTGMIQ
FVCVQEHRDSYRSLTAECIHIHPGSCVYKDRPKFIVAGEIVRTSRMYAMSVSPLSKKIAELIAPALLERRGRAEKHGTSP
TRAAFLKKSTLRKGPRKRRVRVGRASLR
>SEQF2545_AGK84171.1 two-sector ATPase, V(1) subunit D [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKTPLAPTKSNLAYVRDQLGLARDGYRLLEQKREILFMELTSLLEEVHLLETELDKRRKQAYASLWQLLLAQGRDDIAAC
ALVTPVPCRVQQEVLLIAGLRFLRLDAVMQPPKLQYAALGSSACMDRAREDFGLLLQTLTRMASVQTIVWRLASEMRKTQ
RRVNALSKQIIPQMCETCMYIESVLEERDRESTFVLKSLKARKDPTTTL
>SEQF2545_AGK84172.1 two-sector ATPase, V(1) subunit B [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKGVWYRGLSSIDGPIVVAKRREGAFYGEITAIRDRFGALRTGRIIDLSQECCLIQVFGSTLGLSLDGACLEFLDVPMQL
RVCEGLMGRVFDGLGRPIDGFPEVLSSQLRNVNGYPINPYARVYPRDFIQTGISAIDGMNTLIRGQKLPIFSGNGLAHNR
LAAQIIRQAKILGTDEAFVMVFAGMGIKHDVARFFVSSFEETGVLSKVVMFLSLADAPSIERIITPRCALTAAEYLAFEK
NKHVLVIFTDMTNYCEALREVSTTRGEVPGRKGYPGYLYSDLAELYERAGRVKGSSGSVTQIPILTMPNDDISHPIPDLT
GYITEGQIVLQRDLSQRGLYPPIGCLPSLSRLMKDGIGEGMTRADHHAVSSQLFASYARVQSVRSLASIVGEEELPALDK
CYLRFGDLFEQYFLTQDEHEDRSISQTLDIGWSLLSLLPRTELYRIDPKLIDQYLTASCSAVSDQLRKAIEEARTPVADA
>SEQF2545_AGK84173.1 two-sector ATPase, V(1) subunit A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIKDDVVTGRVVRVSGPIVYAEGLSACSVYDVVDVGEASLIGEIIRLDESKAVVQVYEDDTGMRVGEKVTSLRRPLSVRL
GPGLIGTIYDGIQRPLERLFQEDGAFLRPGARSQPLDGSVRWDFRPHCNERGEALCAGIPIAPGSVLGTVQETPSVVHTI
MVPPDIRGSVLSSFKGAGAYTIDEEIGRTDLGEPLFLSQYWPVRRARPFSKKLAVCEPLVTGQRAIDVFFPLSKGGTAAI
PGGFGTGKTMTQHAVAKWCDADIIVYIGCGERGNEMTDVLSEFPKLIDPRTGRSLMERTILIANTSNMPVSAREVSLYSG
ITLAEYYRDMGMHVAIMADSTSRWAEALRELSGRMEEMPAEEGFPAYLPTRLAEFYERAGRVETCVAREGSVSIIGAVSP
PGGDFSEPVTQHTKRFIRCFWALDRELAHARHYPAIGWIDSYSEYAQEVSAWWSKYDPRAGALRAAALDLLRKEQRLQQI
VRLVGPDALPGEDRLVLMVCEMIKGGFLQQNAFDPTDVFSCPEKQVQILRTIVDFHERAVVLLRAGISLSALSQLSCREL
IVRMKTTYGNEDVHKMQKVYDTMCTEFDQLSVCAAARTQGGEKVE
>SEQF2545_AGK84174.1 hypothetical protein TPFB_0530 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEELRSTEVLERDIYAEARKRADHILSCARADCAQLEAHASARVQDITRAVEQLFAQRIAAYERNAQAVIPLERIRQTIR
AVDARVQRALASYFEKIGEEKRLRVLARLLERYAPLIGEQKITVRFFGYCESRVRDLLNQALPRAVLRSLTPFDKAEAWR
AQCSDGLTIETEDGTLQCRSTIEEICAQLLSEKRQELACALCGNGVVA
>SEQF2545_AGK84175.1 two-sector ATPase, V(1) subunit F [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTYCIIGEQELVLGFSLVGVHGFVVHSPEEAARAFSQVTRPPSGDRPAQVLILTQRAMSYLREEVRAWQMQGELPFVVEV
PALHEQGNVRTSLRESIRQVIGAKV
>SEQF2545_AGK84176.1 hypothetical protein TPFB_0534 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVERDVADVFVYAKLSGLCARLWVGERLGTLQGVGTLCDLWVRLFSEPAPRSAGAHLVGLIQRRVEACLLRDCVRAASC
YQEPPSLFSALLARYDYLYLKTLSSSESQAGFRVCQPPDLGRFSLFRWEKWPCIEAVTRGSPVSWYNRVPRSDERVLWDL
RLDQSYYHALWQTLCSIPEDDRTACSRLVREEVALYAVGWVLRLRMFYGVQKKDAPSELSSNGAIRRCLGTWWKCILFAW
DCSLTERGAWSGWRYERFLNNPVDGVQWEPDLDAFERAGSRFLYCLARTVFHAQLFTPATIVAFFMMKRFEARGICALAE
CIHAGSARTLPREFLGEAAYV
>SEQF2545_AGK84177.1 hypothetical protein TPFB_0535 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSAAWVGNMDKGVMVRLAEVEDAAAVLVEKAQEQAQRMRESAEAAGETLVKEAEGSVVEAQEQAWHEACARIDAQRREAC
GQLERELSVLEEDVERFEAFLDGFFFG
>SEQF2545_AGK84178.1 hypothetical protein TPFB_0536 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVLSVMILSLLVVVCLLVVTLVLLQTEEGDGLGGMFSGGSRSAFGSRSASVLTKTSYVMVGLFFGLTFFLALLNRAPDD
TGLQKAAQQKQAETAVEWWKHPPKEGAGAPTSPESTGPAAGNSSGSGVAVPPSPEVRE
>SEQF2545_AGK84179.1 hypothetical protein TPFB_0536a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRYCVSRFLFLCRSHGRFSVLGTGSERLKSLFLRTLWCSMRHGCAERYDTLTPGGGLPSGGHASALAD
>SEQF2545_AGK84180.1 triose-phosphate isomerase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRGYFIAGNWKMHKTCAEAVALAQELVRELRGGPHTYMIAPSFTALDAVGKVLRGSNVLLGAQDVSSEEWGAHTGEVSVL
QLEDLGVQVVIVGHSERRHGRGENDKLINQKVRRVLESGLRVILCVGERLQEYEAGCTNEVVGTQVRAGMADVCGSLMHN
VTVAYEPVWAIGTGKTATPAQANAVHAHIRSVVREMYGAAIAEALCIQYGGSMKAENARALLAEEHIDGGLIGGASLEAA
SFVPIARSV
>SEQF2545_AGK84181.1 hypothetical protein TPFB_0537a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRFSLGLGRDLLARVCLCGGSIEQFLVELSAGCLWCERKDVLRRGYARLFYRGELEDA
>SEQF2545_AGK84182.1 phosphoglycerate kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMLRTCKDVTMRGERVVVRVDFNVPMRDGMVQDDTRVTAAVPTLRYIIEQGPRHVVLISHLGDPTRDADKAEGNAKKDGC
PFDRHAFINGKHRLKPVADCLAKKLGVPVHFAPSCVGQREFIEGLPDGSVVLLENVRFHPEETSGDAKVQEQFARELAQY
GDIFVNDAFGTAHREHASTVVLPRLMRRRVAGLLIEREVRYLEPMVCNPKVPMVAVVGGAKVSSKIAVLESLLRTSTALI
IGGGMAYTFLKAQGVGVGTSLVEDDFIDTARMLLQKAQSGGVSVVLPVDHVCASTFCADAQPVAVDDVHIPMHLMGMDVG
PRTLEQYRAHLKGVSSVLWNGPVGVFEFDAFAHGTRVLAQLIAEATDAGATSVVGGGDSIAAVSKFGLASRMSHVSTGGG
ASLKLFEGKVLPGISCLET
>SEQF2545_AGK84183.1 hypothetical protein TPFB_0538a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRLILTIFQKKIQYPHRSDASHHCSPACAPYTRTGWGTDPSSLLTFSMRNDIPRRVLIPL
>SEQF2545_AGK84184.1 anti sigma factor antagonist [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MELKVRQSGGICVVDISGDMDLYHSYKLKDLVLKLFDRGPRCIVIDLEAVEYIDSSGIGVLIYLCSTVKKLKIHFFISGV
HGSVKKVIELTRLLNYFPIAESVDEALARARSSAPPQTGSL
>SEQF2545_AGK84185.1 hypothetical protein TPFB_0540a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDTLYPHTALRKVDLPEEGLPIMSDTPLLGEAPSVTICTVLSIKERRYHCSPCSGTRQQKAVGYLTLPRVGGFNP
>SEQF2545_AGK84186.1 GTP-binding protein Era [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVTDGASPRSGVSLIIGRPSSGKSTFLNAVCGYKVSIVSPIPQTTRNTVRGIVNIESDQIVFMDTPGYHRSDRKFNLRLQ
SLVHSNVKDADVLLYLVDATRQFGEEEAAICALLAPYQKTRVLLAFNKVDVLHNSTSCDEYAFLHRQGSVLRAGSLGRAL
HAALPHLPADRVFTISALHQVGLDALMRTLRDLLPEAAPLYPQDCYTDQTIAFRVTELIREQAIARCRDELPHALYAGVE
DMELRRGKRELWCRAFLAVERESQKAVLVGKKGAVIRAIRLDAIRALRTLLPYHISLDIRVKVDRSWRQRDHTLSSLLY
>SEQF2545_AGK84187.1 diphosphate--fructose-6-phosphate 1-phosphotransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSISLLQQERHRYLPKVPDLLRGDFRRVCARRGLSTTAVADYDALRSLFARTYGQPLVNFVNASEKNEDSPMETAPEPRG
LRVAIVLSGGQAPGGHNVIAGLFDGLKRWHADSVLIGFLGGPAGVLSGDHIEICADRVDAYRNTGGFDLIGSGRTKIESE
SQFAAAAQTVTRMALDALVVVGGDDSNTNAALLAEHFVNSGISTKVIGVPKTIDGDLKNEAIETSFGFDTATKTYSELIG
NIARDACSARKYWHFIKLMGRSASHIALECALKTQPNVCLISEEVAAQSLTLAQIVQSLCDTIATRAQHGEHFGIVLVPE
GLIEFIPEMKALITELNEVMARRAQEFEALDTPDAQRVWIEQALSASARAVFNALPAEISTQLLADRDPHGNVQVSRIDT
ERLLILQVTERLAQMKQEGTYTGVFSSIAHFFGYEGRCAFPSNFDADYCYTLGLTACLLAVHRFTGYVASVRNLTSSVAE
WAVGGVPLTMLMNMERRHGSQKPVIKKALVDLEGMPFRVFSRRRASWALKTSYVYPGAIQYYGPPAVCDEPSVTIRLERP
APAANSSFGHRSS
>SEQF2545_AGK84188.1 hypothetical protein TPFB_0542a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MWGCGGAVVLFFVYEGVIIDEYFSLATGTASLPAKGPRSSSGGLSARLCASRLIHHCGGRL
>SEQF2545_AGK84189.1 crossover junction endoribonuclease subunit A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFESISGILTLHERERLCVEVHGIEWEIAVSAYSSAAFGEVGSHVKVFTWLYHREDALRLFGFSNVQERTLFLSLTKVEG
IGPKQALKVLSSISSQALCAALDTGDLCALQRIPGIGKKTAQRMLLALKGTLALTDAASCAQSQTDDRAAHPSNLGCAPH
AREIEDLVTALVQMGYDRKMAAEVIAQESAALCSVGRSLYEEEATVLKRAILALSIAHPHAVAPAAE
>SEQF2545_AGK84190.1 hypothetical protein TPFB_0544 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSSKVAGACVGVIFWIVGTGSRCSAASVPHSIGAIQGEGHRSAYEGKHVRDVRGVVTAIARSGKRPIGFYFQDPHGDGNP
KTSDGIFVYCGKAFPDSLRVGDYVAVLGTVSEYISKGNARDLSVTQLVIKRAQDVRVLAHGRELPEPVLISYARVSQPVF
VSNLADLAPDAETIDFYESVEGMRVQMVNPTVPAVAYRSTYYLLPGDTPSTRLNMHGGYVYEQTHIRPVLAFCPRRMFDS
LPEVFKSAPPLPGDSFEGTVVGIMGYSSSSYQLELAEPLPPLRRSGFSPEVSTIQFNARFLNIASYNVENFSAGNKADSA
RARVFAKHFVNDLKAPDVICLVEIQDDDGAKKHHHCTSAQHTLDLLVRAMAEFSAVRYKAVNIDPQDNAPASVQSLDADG
GQPGGNIRCCYLYRTDRVQLVQDQTGSAGTGTFHSVAQMVRGGRQMVKNPARIGVGQESFQNTRKSLVAHFQFVSGVNKG
KDFVVVTNHFSSKRGDDPVWGSTQPAQEHSKRKRIQQAAQVAAFVAALRRERADLPVVVAGDFNDFWFSDVIQKFTAVGM
HSALDLLPETERYTYVYRGYSQTLDNILSVGARTETADILHINAEQPARERVSDHDPVFVQLSW
>SEQF2545_AGK84191.1 sugar ABC superfamily ATP binding cassette transporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKGTGMCVALLLCALGAGACKRSEKPTIGVVVYQYDNTLVARLRHILSTVGKKHARILIVDSQASQSIQNKHIDQFIARG
VHGLAVNLVDHRAARTVIEKAQQARIPLVFFNRMPDLSDLNRYARAYYVGVKDDELGLLQSRLVAQYLERTPSADKNADG
IIQCVVLKGDPDHKSGARCARYVCQALREIGLKGEIIGEAFALDSRVKGQAAMHTLIHTHGDRIEAVFANNDDAALGAIE
ALQSAGFFKENKRVPVVGIDATASALKAIEEDLMLGTVLNDVSSQGKAILNLLFALMGDSVPSIPAEDSTAFTHAGNGVA
GRAAVFGTAEKQCVWIPYKVVTKENYRTVQNYLR
>SEQF2545_AGK84192.1 S1B subfamily peptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKTASLCLRSAWLNVALGGVLGVLSGCRVFDERADVRVDRTGKEYLDAQVACAKEELRARPLRALMCAIALKRNAPAHQK
VAQLYAQALARVKEAFRYSVEKQKWSEALVFFRSLSALRIPLKDWTERSLHRAQIEQWKKEGAHVLVAAQEKRAGTSAAR
SPAAMIKGTVTILVDRGIRVEHGRGFADRVIGSGFFIDKRGYIVTNYHVIRSEVDPAYEGYSRAYIKLPSDNTVKVPVRV
VGWDALADLALLKTEITPEVVFGLGSSKNLDVGSKIYAIGSPAGLERTLTSGIVSAKKRKLLSVGGGVLQIDASINRGNS
GGPVIDEEGCVQAVAFAGVEQHAGLNFAIPVELLKQVLPSLYRGGLVTHPWLGAFGETHRVWKNAGVGGVLSSYVIPGSP
LSYAGIPEGAIITTVNDASVSCVADLQAELEKYVPETIVRLAGYRLRDKSKLHDLAAYEQDEWYCQLGVRPEHPARILYK
YDLSYRAFLPLFGMRLARTGTRNTYRVESLVPGNFADEHGFSTYDVIEIQNIYMIEASEAIVADVYAKRRKAGYIDTFMR
LVAALDNPSFF
>SEQF2545_AGK84193.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRKVNCIKVITRAHTLGYCGGVRMAVRMAEHARAHHRGSVYTLGPLVHNPVTLARLRARGIECLDPAHLSFALHAPAAPG
AAPHAVEEKTARTVVIRAHGVAPEVYEALERSGAQVVDATCPRVKESQRRAQGFAAQGLHVILAGDRNHGEIVGIEGYVR
AGAAQACSHLPGGAPDGMLPQVQCFVVQNAREAAALPCLARAALLAQTTITQGEYDAIAAAARTRVRELTVARTICAATA
RRQAALRALAPTVEALLVIGGAHSANTQRLLHTARETSLPTWLVERVEDIPPDIYAFSAVGISAGASTPDCVIAAVEQAL
RTGGAPVASRVSSSALPKVGTCRAVCAAATSSVGSAGASGAVSPGAVRPFAVGSVR
>SEQF2545_AGK84194.1 hypothetical protein TPFB_0547a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGARDNLNAIDLSHITHWGTKPDENWRAECTKGTQVMQGRGVVVSSSSFIYFEKDTLLFLRECVRMARSL
>SEQF2545_AGK84195.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRQNGAVPMISCSVRRRPRWEPQVGAAFLAFALLPVLASGGGNGNHPGKEQFLQFLIPSGGRYEYLGVSFTALADDASFF
EANPAGSAGLSRGEVALFHHSQIHDSHTETVSFARRTQNTGYGASVRAFSSESDLKSFFGGNSGSSKSGGHQGKQGKGFV
AIANASHTFCGQYRFKGVSFGCNFKMGFRKGKTDSHVTVAGDLGLRAAFSVAKNFGSNEPNMHVGLVLKNAGISVKTNGS
EVKHLNPAIAVGFAYRPVYAFLFSLGLQQTLTKKESPVCSVGFMFFCTQHVTLLASAACKGKAYALSGGAEIRIGSFHLD
MGYRYDQIFQAAHPHHVSVGLKWLIPNGGTQADRALLVKESYLVGLRFYDQRRYQEAITAWQLTLRQDPGFEPAAEGIER
ARRFLKLHEKLSLFDILN
>SEQF2545_AGK84196.1 hypothetical protein TPFB_0548a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIFSTSLPWRTPALLHAALQRAQERFSPCGSGNTRALYVPRTHALHSPPPPQGGPRVTGPIRKCP
>SEQF2545_AGK84197.1 S14 family endopeptidase ClpA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLQDLSANARKVLLELGQTVAREARASLLQPEHILLALIQHKVGRGYKLIEKLIEDVATVRLILEQHVLTNEGDVASPQD
LPVSGRVKHLLDIAAMEARSLRCAYIGTEHLVIAFAREEQNPLFQSLIREGLSLDDLRNASIISSPHSDTTRTRLERKVA
SVLDEYGTDLTERARAGALNPVIGRNKEITRVIQILCRRGKNNPVLIGEPGVGKTSIVEGLAYAIVREEVPHILLHTRVV
SLDLAAVIAGTKYRGQFEERLKRIIKEVEETEKVILFIDELHTLIGAGGTQGSLDAANMLKPALARGQIQCIGATTLAEY
RRYFEKDAALTRRFRSVLVREPSFEETCTILRKIKSHYERHHQVIYQSDALEKIVELSRRYIPERFFPDKAIDLMDEVGA
MKRVQQRADTQVLRSFSIKVANLTTETERAIALEDWARARSLHTDVVQLRRRLHALKVEWSAREALSIFAEDVAQAVSLM
TDIPVHSLEGDELCRFTNIERDLCATVRGQREAIATLARAIVRARVGISSDTRPIGSFLFLGPTGVGKTLLAKTLAEFLF
GSADALIRIDMSDYMERYNTSRLMGAPPGYVGFENGGLLTERVRHRPFSVILLDEIEKAHPDVFNVLLQVLEEGELQDNL
GHTVNFRNTIIIMTSNAGTRGLGENVPGFQTARARNIEYRQLRVQALREIKRIFSPEFLNRVDECVVFAPLERETLQEIL
ECELKKLAERLRGKDIVLRYSAAAKAYCLEHGFDPFLGARPLRRVLQQEIENELALRMIHGTLRAGSCVHIDSDGARLHL
STEKSYLTLHPQEI
>SEQF2545_AGK84198.1 tRNA modification GTPase TrmE [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRAHEYALDDDIVAIATALSPAALGIVRTSGSSSIERVASFFSRAQALTRARAHTFLHGWILDGKTRVDEVVLLVYRAPH
SFTGEHAVEIICHGGVRTVQAVYRLCLAQGFRAAQRGEFSFRSFFHGKRDLTRIEAIQSLVDARTCAAQQQAVLHLSGAL
QQEIAALTRALLAFSATLQGEIEYPEDEETRVHDIDMRELEPLVERLRRLRACWQERALQRTGVRIVLGGCPNAGKSSLF
NALLGQDRAIVSSVPGTTRDWLEADLDLSGIPVRLCDTAGLRVTDNPIEAQGVVRSEQLLQGADCVFYIINGRAGVQAAD
CAFLSDCAVPLVVVVTHNDLMSMSERTQVCQAVQPFISAPVLSCARSQDARGAGEQCLAGGKNGEVRDRAPRAFVCVSAK
THAGLDALRAQTLHLLHGGQVPYEELSLGSERQYVLVDAAVQALEHAQEAYARGFGLDAVVHDLEEALYHCGALTGEVHS
EDILDALFEKLCVGK
>SEQF2545_AGK84199.1 membrane phosphatase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEEFIFWNLSVIHAVQQAAHPVITHAVVLFTFFGGKGIALCSLWVLWCVEYRKGLAIAYALACSEGLNYALKGLLRVPRP
FVRDPSVKLVFHDGFSTPSGHAQASALFVLLARSYPSAKTPVPCFCAPGCGTDRQVGDRENPSSYGQERTPLARTAWTGV
AGVLFVGVIGLSRVYLGVHYPIDVLLGWLNAVLFGALILGMRRALRRGVVFFTRIQEVSGRSFAGLRFSAVVCIALLLAV
GGADVSMCGAFCGLGAGHLFIFDRWVTRRAPAGGVGFHAAGGSFTQKVVRFCVGCVFCSVVSSALHALFSGAPAEYARLL
RFVRYGIGASLSTGVVPLLFLRVGLAGGLPFHAPAPTAVRER
>SEQF2545_AGK84200.1 hypothetical protein TPFB_0552 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQSLEPLITKQLRPAPVGVPEGTPQQVLYVLTWSALTQVDKYRISTAVPAVSGVYELYYMDEARALNLLTAAHAWYGGLR
GNVRAAVDPHETADPARRALLTDATLYYRYSVSHSRDDMCDLVWFLHTQYFPGSVRVQHSGRYSAIFVQERAPDRVYWLE
DLPHRTERGSMQTRVSK
>SEQF2545_AGK84201.1 hypothetical protein TPFB_0553 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEKQSPAQTISLFVLLALMFVLVCMLFVPYLTVLLWSSILAILLSPCYRALCARIDMHAFTRTRHLVSHMNGEDGCTAAI
TRATRFQKKMLAAVFSLVITLLVTTVFFFIAISLFGQGKLLFDKLSLFFREYDLFEGAKQRSFTALIFKLSRGTVDISTL
NVEEHLLRFFGKHVESVFVYTQIFVKNIARAALSTLFFSFTLYFFFLDGEHLSCLLIAALPLRKRASAQLLEKCKEATRH
LFKGLFSIAFYQTCVAFVFYGIFRVEGPMALAMLTFFASFLPLVGCACVWLPVGISIGFTSGWMRGTLFLFVAGSSITII
DSFLRPLLLQNKMRIHPLLIFFSMLGGVQTFGFNGMVLGPILVILLFTVIDLTHDGESHYTSIFHDPPAAGVHAQSIHRQ
GKK
>SEQF2545_AGK84202.1 phosphoglycolate phosphatase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCTRSRYTDKEKNRDILLLGALFITMRPMTRACIFDLDGTLTNTLGTIAYFVNMQAAHYHLPPIPSEKFALFLGDGSRAL
IQRVLAHYGAAAQTISEDEFLQRYCLAYEADFLQRCTVYPGVPEMLVELKRRRIELAILSNKPHSIAQKVASAFFGDNVF
SVVLGQREGVPVKPDPAGLFEILRTLNVETAEALFVGDTAVDIRTASAAQVRSVGVLWGFRDETELSQAQAHVLIRTPAE
LLQHLSF
>SEQF2545_AGK84203.1 DAACS family dicarboxylate/amino acid:sodium (Na+) or proton (H+) symporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAGSAGFWLLAKLSGGMVCGVALGLCVNESVMAIIHTGKTLIGGVVFFVIPLVIFGFIAPTVLSLKASAGRMLGSFLVLS
YLSSVGASLFATAMGRVVIPYLRIPRTVEGLRTIPKVIFTLEIPSLMPVVTALAFALLVGLSALWVKARAVEQVLYEFRR
MMGEAISRVLVPLLPFFVAATFAELAYSGSLTRQLPLFAKVVAVVIVGHLLWLCVLYLVGWILSRKNPFEVLRHYGAAYA
TALGTMSSAATLPVSLQCAHKSRALPAEIVDFAIPLGATTHLCGSVLTETFFCLTIAQMLYGSMPSLADMVLFSCLFGIF
AVGAPGVPGGTVLASLGLVLDVLHFDTTGTGLLIAIFALQDSFGTACNITGDGALALMLRGLRYTPAGELRWA
>SEQF2545_AGK84204.1 aspartate--ammonia ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MALTTEKSFILQQQGISFTKHTFTQKLMEHLGLIEVQGPLLSQVGDGIQDGLSGREKAVSVSVKQIPGTAFEVVHSLAKW
KRHTLARYGFQDNEGLFVHMIALRPDEDSLDQVRSVCVDQWDWEKVVPVGSRNLAYLKDTVRKVYGALRESEVLVSERFG
LRAFLPADIVFVQSEELVRRYPHLDSKGREDAICKEHGAVFLIGIGGVLSDGKPHDVRAPDYDDWTTPSEGEYKGLNGDI
LVWNPVLGRAFEVSSMGIRVDEGALRTQLALTGDEDSLACSWHQDLINGRLPQSIGGGIGQSRLAMLLLQRKHIGEVQAS
VWPRSVREEFENIL
>SEQF2545_AGK84205.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKRMWRAVRTLLIICAGGTGALWAHPHVFIRTKVTFQWQKGVLQRAHITWEFDPFFSADIISGYDTNKDGLFDKKETQQ
VFENAFIHTKHYSFFTFIRSGESHARRARSQAARTSPQSVQHFSVSQKDGTLSYHFSIDLSSYQHAKSAPPGTRRTLYLA
LYDHSFFCDFRYAEHDTVRFVCDKARVQPSYEIVENRTAPVYYDPFDSIESTPQYEHWRPGLHTYYPKEILLRYTAP
>SEQF2545_AGK84206.1 putative NiCoT family nickel (Ni2+)-cobalt (Co2+) transporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKVGVRVRACILCALAACATGVLANPFFGGAPARPRRQRTPELLLRRYALVHQRLGAAIVQWSKTHSTRAWWITVMLSF
AYGVLHALGPGHRKAALFSFYLGRNAPVWEPALTAALLAALHGAASLLLLSAFRGVSGAIGAHSARTMWYMEVGSYGLLT
FLALFSLVHELMHLFPSGGRYFSCGCSAHTAVCMRTGTVAHMQWGTMLLSGLFICPAALFVMILVLSLDAVGLGVAAVLS
ISAGLALPLMAVGYLAWASRAGIFYRMQKNTRHAQAVLSVVSITSYGIMLIVCTSALVASLG
>SEQF2545_AGK84207.1 thiamine biosynthesis ATP pyrophosphatase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVNGSTQYLAHVGELSLKKGNRRQFEVQLERNLTLMLRSINPHVTVRAGRLYLSVPASFEAQTTAEQALSCLLGITGWAA
ATACPKTMEAITRCAHAEATLAAREGKRTFRIEARRADKRFCRTSSEIAREVGAVIHQSGALSVDLHYPDVVIFIEVRER
EAFLYGARRRGLRGLPCGVSGRGLLLLSGGIDSPVAGYRMLSRGMHIDCLYFHSYPYTPPEAQKKVEDLAKVLARYGLST
TLTVVSLTDIRKQLQTHAPAPSLTLLLRMCMMRIAEHVAREQRARCLITGESLAQVASQTLENLTVTSACTHLPIFRPLI
GADKEDIVRTATEIGTYAISIRPYEDCCTLFAPKHPVLRPEVEEMQKQYQSLMLGPLLEDAFRTRKRTRIYGNYGVQESG
E
>SEQF2545_AGK84208.1 transketolase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTEEAMRAMALSIRSLTIDAIERANSGHPGLPLGAAELAACLYGTILKHNPANPSWFNRDRFVLSAGHGSMLLYAALHLS
GYDVSLEDIKNFRQVGSRCPGHPEYGCTPGVEATTGPLGQGISMAVGFALAEAMLAARFNTDEHAVVDHHTYALVGEGCL
MEGVASEASSFAGTMRLGKLIVFYDENHISIDGSTDLTFSEDVAKRYEAYGWQVLRGSMYSYTDIMDLTACAKRDDRPSL
IILRSIIGKGAPTVEGSARAHGAPLGEAGVREAKKALGLDPACSFFVAPELTAVLQKRKCECAHVEDSWNELFEAWSTQY
PEKRADWDAAFVPGGVSTSQLARVVCPHFEKGSSLATRTASGKVLDALCSVLPNLVGGSADLRGPNAVAVSSLRPFSAEH
RAGGYCYFGVREFAMAAIVNGMQLHGGLRAFGATFMVFSDYFRPALRLAALMRIPSVFVLTHDSIFVGEDGPTHQPVETL
AALRAIPNVLVLRPADAEETFEAWKIALLHRNGPVCIVLSRQNVPVFEKSDSSWRSTVEESGAYVVREGGATPELTVLAS
GSEVDLALRAAQLSKRRVRVVSVLCKERFEAAGDEVQRRIQGGARVVVAEAGVYQGWGAWAKREKCLVLDRFGESGPGTQ
VAQALEFTAEALVEIILDWLA
>SEQF2545_AGK84209.1 hypothetical protein TPFB_0561 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRLSDIYFCSTVVSALRVPRMNGMLRTSVLVCIGCLSAAIPARLGARAVPPLSSAVVDEAALLSVQEARGIRALLEGLAR
PSGDGSSRSHPSPAPEAHARTLHDGTPLQIAVLIVDSLQGDSLEDFSLRVAQEWGIGSRAQDTGIVLVIARAERKARIEV
GYGLEDRVTDVHAHQLIRGTLAPCFQAGAYAQGVYETVLRLATLVRGQHEVQQFMQPRSVQPAVPRRGPVRNSAGSVFFF
LLLFYCLGGRLLPGGVLWPLLFFGTRRRYDPFGSGFSGAFGEWAGDGGGFSGGGGRFGGGGASGSW
>SEQF2545_AGK84210.1 N-acetylneuraminate synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFTCGGRCFRPDADILTIAEIGSAHAGSFDRARALIDAAADAAAAAVKFQLIYAHEILHPLTGAVRLPSGAVSLYQRFEE
LEVPLSFYAQCFNHARSRGMLVGISPFGPRSATEALALKPDFLKVASPELNYPTLISTLAAAELPLILSSGVCLLKEIEG
ALAQCRQYTKQGSSHALLHCITAYPAPETEYNLALLPALATIFNINVGVSDHSVDPLLVPLLARAHGACIVEKHICLSRT
DAGLDDSIALDPADFRTMTAALNSCARRSPSQIISFLHERGYAPHVVRAVIGSGEKVLAPSERAHYQKSNRSLHYLHAYP
RGTVLQKENLVIVRSEANLSAGEAPEHANLFVGAVLQRSVHAGEGARFGDIIQKGTCL
>SEQF2545_AGK84211.1 DnaJ domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSMTSFYERIGAILRDRLNSDEDPFDQWDNRGGKYRTCAGRMERRPPPKKNPPPGPVRVPVPPELVEDFAVLSVPAGLPL
SYCKQSWKRLLKKYHPDVFTCTHTSEQAADIVRRINSSYKRIETWFETGALPTDNKS
>SEQF2545_AGK84212.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTRVCRALLFVLCGIFVHAQENELHFFGPRTDVLVVFTASREAQERETRAVQQLRLLVQDFEHQTPDVSVLVAITAHDHP
PVPDFVPVDRLTGTKKLISLISSYKAPIVLILDETTGPPRLHTGAHRTVCPSWLLQAVYQHLTSHHVPIRYRDFDAILHR
LGWLHEDPRHALYIKEHIPAVRMENSLYPPGALHTLPALLTQVYSEEWDTHYVSVSYGGTLYLIREQFFVILILGAVITL
LLSLAIFSFLSDSRKRHYWNTILAMWWLPAILGVLSVCSVFVATQLTALFFLIRFGTHTSTGALPLLALIVKHSIAIALS
CVCMANSKTIRDSMLHNGFIGGYLASTLCLLYAVLFSVIDFSLSAVFALEYALSLVFFSAQRKTRRRIMLAMMFLLFAPF
LYAYLKNSAVTAPLSFHQSNVFFALGCVPFMLFMLTLFFEREKSHPRIPFIRRRNLLLSGALLTVLVINGVLWSVSLSST
RIPQEITACYRISERGLTLSLHSPLPIPRHIRARTHARLSTAEIQKAQDHLQISMDSRSYFGGRINVLEVRSQLRAQAIE
LRITSPHGTAAYEADRPFTRLEQGSVVRFISQARPPLPFTVTFSGDQNSTMQVQATVWTYDNPLQDAPPVMQDTTVRFIP
MFELTRDVLFPSPSSQGVHATPEKNACIRDETVPNLQE
>SEQF2545_AGK84213.1 hypothetical protein TPFB_0565 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTTVRVILQRCARGICSNKGRYSANQVLLFCILTLSLWTPFLGPALRHPAVYIRHKSVKNIYLAFVDPLMHTAEQWGIDT
VFPLLRESFLHATGLIQHPEWEDTFYHCEQRSYEPAAALAESVPSPVLQEAVAVSPPGVAVNDSVAERKTTAPARVFSRT
ALRILMCGDSQMRYLTGGALQVLGTSSHVQIQEVTVSSSGFVRTDYYHWPRKFLALLDTHTQQEPYAAVIMAFGMNDYQN
FYDADGSLCVTKTARWERAYEQKMRACLNIILHTVPKVYLLGMPETRNKQLNEKLVYIEHVQKKVVAQYDPQRVRYYSLK
PIVPGVHGTYASAIRDTHGRWVHVMHKDGIHYTIEGGAYVMETLLPLILADLERSRHGYMRSSLGSHELPATKGMERARH
ASTQT
>SEQF2545_AGK84214.1 alginate O-acetylation protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFFSLLSPAAFLFIFFILYWYVFRTATQRVVVLLVANFLAIAAFDIRFCIPYLVLSALAYSCGLLILMQKSFLWRKVLLI
AGTLLQILFFCLFKHFSDMLSLVRAFAPAYFAQHTWHQHVKDWNIWHPVGISYCTFKCMSYVFDVYLCKIRRREPFARVL
LYVSFFPQMISGPIANASHFFTRLPHNLRAGESPLDRPIHFDRAVVLLYTGLVKKVIFADFLSILVTDKIFTLPSAYSST
ELLFGLISYSAVLYCDFSGYSDLAIAVGLLFGFETPANFKRPYISQSVTEFWRRWHISFSQWLKEYLYFSLGGSRFGIKR
TVCALFFTMLIAGLWHGVRLTFLLWGMAQGVALVIERVYREKRRVNGANAFGSSSVMGRWKVRAMRCIRVSALFLFVSVG
WLIFRAPSFAEVWRYVTLLFRGSWHGPFQVITPFTALLALCALCVQLPSDRTRARAFACYCAVPLPVKALCAAFFFFVLS
VMTPSGIAPFIYYSF
>SEQF2545_AGK84215.1 hypothetical protein TPFB_0567 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKIVALLALILLLILAGFIWFDYLGVLDAKRAISPLYRLFGRSVPEGVVSTADPDLDADRYAKRLEALGERAEELDKKD
AELQEKEKDHERVSQELDERLRALEDKEKSYNLLVAETNERRGNVRKIAEYVSGMPPESAVKILLKTDDQDVIEVFRMVD
AAARQRGVNSLVPYWLSLMPPDRAAEIQRKMANKPADFP
>SEQF2545_AGK84216.1 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MITIFEALERVRVIPVVTLERVEDAVPLARALITGGIRCMEVTFRTLVAAEAIAAIRQECADVLLGAGTVLTVEQAQQAQ
AAGAQFVVSPGFNPRVVAHCLGHGVPIIPGIASATEIERALEFGISVVKFFPAELLGGTAMMSALARPYTAVRFVPTGGI
HLNNLAEYVAHPRVLACGGSWMVPAQSIAAGDFSQVTALSQQTLQIVGVM
>SEQF2545_AGK84217.1 Xaa-Pro aminopeptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIPLGKRHGHSAVAVCSRGVSVFRGEKAMDGVRGRLSALRSLMRAQGVDICYISGENAHGQIDGAREYFSGFTGSAGIVV
VTAQRAFLWTDGRYFIQAERELSACEVCLFRTGQAGVPRVTELLRTELRAFSSGPGHGGGTLAVDGRTISAAVWEQFQQE
LVDVSLRLDFDGALLLPQEHRVSVVPSPAFLLDERYTGLSAAQKLTQLRAALSARSCDATVLSTLDDVCWLTNVRAYDVP
CTPLLVAYMVVTHTRAFLYVDMRKISSALHQALYAQGVECMPYDTFFDQVCARCADQEPTVHAVGKGRAGVQEVAGRTPV
VLLDFERSCAALVDLFRASPQVCRPQVERSAPSGSLSSVLGIEEDGTETSRGGKSACALQSARDALAAGKEKENKEERGQ
TMCFSVCRGLLPTVALKALKNDTERANVHQAMIQDGIALVKTLQWVYQQLDVGADVDECAVAEFVRAARAVSPSFIEESF
HTIAGYGANAAMVHYRPVRFSALHPAAGQTAALLRARGFLLLDSGAHYREGTTDVTRTLALGPLTDVQRADYTLVLQAHS
ALARARFPAGTSGAVLDGIARAPLWAQGRDYPHGTGHGVGFCLSVHEGPYSISPSAPGRGGTARGIGAEHTGDPPFFSEE
AAWQLRPGMLLSNEPGVYVAGSHGVRIENLMWVVQAHESDAQCVWKEGGEGKEENAAARECTGADRMQPSRCRSFYGFQT
ATLCPIDTRPFVRERLHDEDIAWLNAYHLRVYVTLAPFLDARTRAFLRTCCRAL
>SEQF2545_AGK84218.1 hypothetical protein TPFB_0570 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MWFSLRRIGDLLSWLVGSKGVRGSFCADPVPRVDGAHGGDDPRREEDASGAFHIPRFAARLGLDSAGLLRIQRTVARVEG
HTDGEVALALIKESDSYSVYELFFALVLAGACFCVQLSMVSVLEQAFARFFWAPPSWYMPAFMVASSVAACVLFFFIANI
PWVDRALVPGPLKQQKSYARAVRHFVESGVCNTRNRTGILIFISVLERRVLVLADVGVSAYVPAREWTELCQIITAGLRS
RRAADALCEALTRVEQVLATRMPPQKKSSNELPDGLVILSH
>SEQF2545_AGK84219.1 LemA family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGCACLSSFCWARAGVGVSVSKGLRGTLIGVGVSLAFLLVVYRLFAGSYNRMISLDEAVKSAWSQVEAVLQRRLDLIPNL
VSTVKGYAEHESDTLKRVAEARSRAGGVMQVGESALSDPEKFARFQRVQAEIGGALGRLLLVSEQYPALRANESFLALQS
QLEGTENRISVERTRYNRAVQEYNAYIRSFPRSAVARWGNFSSRPYFTAHEGAVAAPRVRF
>SEQF2545_AGK84220.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSALFSLVAVYVLVCALHKQIKKYASVCYLGSACVSVAVVCVVWSGATKGNFGVRVLLHPLTSASFSTAIFTFVMCASVL
KNGLLKQRVMGLRAELAITAAILTLGHNIAHGRDYLVRLCGSPGDLSTGFLVAGAVSMVLVLLMSILAVTSFKVVRRRMG
AKTWKRVQRLAYLFYGLTYVHLSFILLPTALRGYIPSVVSYVLYTVIFATYALLRVRKALGKRKGACALCSAAVAVSFVA
FVLGASHMVRHTRRAHTERTTRAKARKCSPAEMKDGVYEASAQGHNGKLSLRVTISQGRIEAVTVVGHSDDDPYASWAVE
GVSAAIVGAQSTDVDVVSEATSTSEAIIRAVEKILQQPQP
>SEQF2545_AGK84221.1 lipoprotein antigen Tp47 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKVKYALLSAGALQLLVAGCGSSHHETHYGYATLSYADYWAGELGQSRDVLLAGNAEADRAGDLDAGMFDAVSRATHGHG
AFRQQFQYAVEVLGEKVLSKQETEDSRGRKKWEYETDPSVTKMVRASASFQDLGEDGEIKFEAVEGAVALADRASSFMVD
SEEYKITNVKVHGMKFVPVAVPHELKGIAKEKFHFVEDSRVTENTNGLKTMLTEDSFSARKVSSMESPHDLVVDTVGTGY
HSRFGSDAEASVMLKRADGSELSHREFIDYVMNFNTVRYDYYGDDASYTNLMASYGTKHSADSWWKTGRVPRISCGINYG
FDRFKGSGPGYYRLTLIANGYRDVVADVRFLPKYEGNIDIGLKGKVLTIGGADAETLMDAAVDVFADGQPKLVSDQAVSL
GQNVLSADFTPGTEYTVEVRFKEFGSVRAKVVAQ
>SEQF2545_AGK84222.1 hypothetical protein TPFB_0574a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRKRAISCDGGRRRDPPGRERVGSRVSKQKTGPMAHPAEAIMPVIGGMVRMALSIADPPKKRKDAPVCALHKTLTIPVGR
AYTQALYTEV
>SEQF2545_AGK84223.1 EI family phosphotransferase system enzyme I [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLRAMRTIPPITGIIASAGCAIGPVFCFDTLLPTRSRPGGSRLRPPSQEIARLRNALSYARASLQNLLDSVRAKASGDEP
APEYAVLSGQAEMLADAAFIATVEETLRSCSCDAETALRKAITHVTDALSATSDEYLRARAADIRDAFSGVFDALAHDTT
PTAGSSLPTQGIGNSTPHSPWEPDFSAVPPGSIVVAAHVQPAHALRLHEANIAGLVTEGGSVTSHVAIMARAWSLPLLVS
AQGCKDVAQYVLRVRQTARATDEALRALLDAESSGGKTDALGTLTVNPDMRALRTRMPHPFLTVKHTSTAEQSPPAACVL
NAPLRTYSSDGIRFEVGANIVMPQEACAAAALGAAGIGLFRSEFLLFGSDRFPDEETQCSAYTRALQAMRGLPVVLRTFD
LGADKLVPDPARMCALSDAAEPCAHTASERNPLLGLRGIRYCLAHPELLKVQLRAMLRAGACATCAEGTLRILIPMVSRV
EEIHAVADLISEVADECARAHVSTPDRVALGIMIETPASALMAADFAPHVDFFSIGTNDLTQYVFAADRENEQVSSYADY
FHPALLRLIQHVIHAHRHLRQRPGISFGEQGIGRVVMCGAMAEDETALFLLAGLGLRALSVPSSRIETLHTFLSRISVSD
AEHCARAAVQLSDAQSVRTLIEEHLRTAGITLEKDEEEPSPPRSP
>SEQF2545_AGK84224.1 peptide chain release factor RF2 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVHKSPPSRRACRKYGGVFDVAAYEARIATLEAAAAAPDFWSERARAEALLAELKTLRATLEPWRALRRESADLRALYEL
AREAQDASLEPELSSLFSDISARFEEASLTRLLHEEVDRLDAFVTIHSGAGGVEACDWAQMLMRMYTRWAERRSFCVHIV
DLLESEGGVKSVTLKICGSHAFGFLKGETGVHRLVRISPFDSAARRHTSFTSTYVFPVLDDHVEVHIRSEDMRVDTYRSG
GAGGQHVNKTDSAVRITHLPTGIVVTCQNERSQISNRATALSLLRARLYAYERQKKQQEHQRFASEKKDISWGNQIRSYV
FHPYTMVKDHRSKCETGNIHAVMDGALEPFIRSYLEFLCTSTQCVEPQ
>SEQF2545_AGK84225.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRNGEYSRSHGRSVRTVHPFLLGVSVYQYPVCRTTVNGSYAQSFAALLFFPQIAVAFSATAPAPSFDSFLSARQRHPPAS
SFLASPAAPTHPLFATARTTAAQLLSTPPAPARPRPRPDHVIPKEKWRLAVADFTFHGIPKIFQRYVRPARELLFIELKK
LPLRHFLSEAEQRERAALPHEEAYHARLKERAHLQRARDFVSLHPVSDHARRLRTAAFEKQIKEKEQEIERARVEVRTAR
ARFFRPWLQAEVLVLGAQNEPHALPERFHLATHLRQKKLSALVTGKLVDVAGYVRISLYLSTGLEAEPTREFTLAGPYRE
LPRLMHTLSAQLRSAIENAQPVRIVFDVHPPHARLSFQGVPVEDLSKPLISYPGRYVVDVSAAGYFSATKEIYIENRPAF
SLRVRLVARPQHRVRVQLTDNSAAPIFSGARSVGVTPFSTVVTDLREIFTVGPAGARSFAFIERGTFPNSQPSTLVLPAP
NPNATQDLAYKRDVAYWSFGALCIAVPIALILGSTLADTHQALERAKAASAQSSSPPLPPPAQAGTDALERKRQHLLIGT
GVAVGVAVILSINFIVHAARYLNAVMHNAPQAVRPRADKDIQTLTHRDEAEEDQEEDS
>SEQF2545_AGK84226.1 Sec family Type I general secretory pathway protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKVGLGNLAQKIRRLLGGQAPLDETFFSALEELLIEGDLSLSTAESFCTQLRNAARTRSVHTEDALRTLFAEIMESCVRV
THLAPNPNQCSLYLLLGVNGSGKTTSAAKLAAYYQTQKVHPILFAAADTFRAAAAEQLAHHGAQLGVRVIAHPGGKDPAA
VVFDAGEALRAQKRGLLLVDTAGRLHNKTHLIAELQKIDRIAQTKVSADAYRKILVLDATTGQNAFRQAQTFHEAIGVDA
LLLAKCDTRARGGAVFSIMQELGIPLAFLGWGERYTDLVEANAREFVSSFLHGER
>SEQF2545_AGK84227.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRPRYGWMYSSGIAVHLCAAVCAHSAVPAAWTFAEQTQAQKTDTPLDSSSYAVTSPEEAPNEADPFEKELEHAFERAHV
STGGADSSSHADFVHMEEAGRAHASANRWYHETFDSRQRPSSAVLYEGAQLLHTVHWHYVGDRLFPCEKIITTPHTRIRA
RYNFSGKIVAYEMHTRGVLVYARTYRYDAHARICEKEETTARGNERITYEYRGKADVLEKRYRNGVLQAIIHQKEGAQDV
QVFERGKEIYSTKEVHDE
>SEQF2545_AGK84228.1 putative lipoprotein ABC superfamily ATP bindingcassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSNTHVQTLRWMCFMVRRLNSVRARSANAITSLFFILGIAFGALTLIVILSVMNGFQQGFIGTILQVSSAHVRVYGSVDA
VKRAETLGGYQSFYPFIEAHALLQGNYYRQHGALVRAVPADIFHRDRLLARALPITSGSFNLSKKHSIVLGYELARHLSV
RTGDQVDTLALSGSDTQKIMPGWNKLTVTGIFKSGYHEVDSTFAYIPLDMGTTLFGTTPDITAAVKLNNHERDDRYLFFL
AQHIPDLKAESWREYNRAFFSALRIEKNVMILLVILIFMVVTVNIYHSMRRSIRTRKEEIAMLVSLGAPVSHVQILFIGN
GIMIGFLGSLLGVLLGLLITIHVNEIIACIETAVNSAFFLFSLFSGTKTPSFSVFGTQYFYNVERIPVQIFFQEVLFVFL
FGTGSASVATYLATRKILLLKPAEVLRDE
>SEQF2545_AGK84229.1 lipoprotein/macrolide ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNDPILSVEQVSKSFCCATERIQILSDVSFSVPRAVKVAITGESGCGKSTLLNIIGGMEHADSGIVRVLSCDVLTLHEHA
LTEYRRQFLGLVFQFHHLLRDFTALENVMLPGLIAGKSYREVRARAYELLEKVRVVQRAHHFPAQMSGGERQRTAVARAL
INDPTLILADEPTGNLDPKNALIVQDLLFSLTEEYQKTLLIVTHDPRIASMTDYRYQLQQGSLIRI
>SEQF2545_AGK84230.1 lipoprotein ABC superfamily ATP binding cassettetransporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKQRCAAVNLIRVIFMCALRCAGVCAGYGHTPSLHGDAHHVLPTPVPFLSGTPVAGKRRSFLRKSFFCAALGIGISIIPL
IVVLVVSDGMIEGITTRMIELGSGHLQFIDILPLAPNETATQRYEDAQRIFNAFMAQDFGPYCHSRWMHLQGDGIVIGKT
GRAGGNIRAVPPDFFSSERGLRPFLTVEGSLELVDRPQGVHTLILGKRIAERIGVRCGDTCQILTLVQGGTGRAVPKMVR
AVVGGIVSCGYQELDALWVFIPLTLGMKILSPASALLSFVVKTADAFDAKAMTRFIEQVHEQLPSHFSAYTWQDMNRSQF
HSFRTSRKLLLFIMYLIVLVASVHISSVLVVLMTERRKEIAMLKAMGAPPHVIALIFLSAGLLTALYGLLIGLPLGMWCA
IHVNEMFLFAEQMLNSWRTAIHAIGQLFLRTSAHVPVTPIHLLDPAHYLERIPIVLSVHALCGVAGGTLCLSLAVCIIPA
LRAGRVRPLDLMRKV
>SEQF2545_AGK84231.1 hypothetical protein TPFB_0584 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEERKSYMDRLAEALTRRKVQLDRDILPKALEQYRVQVTAVKAIRSNLLQKGFLHDDAYKYDSKMTEIELPETSPYGENE
KPMVIGSRLSHYQTMLGFLDNYYRFDSEFLIPKRIAKLVALNGTFMWKDFTATTKDANTRGLFDIVQSFYGAADPISIGL
VRDSLQYLVKAHEVISTALKSLSVFHRERYKLLIRQHALDGLDETTVDVNNPEVALDAMKKNFSENAKGHPFYSELATVV
LREDFSANAEKLRAAILREFEESSAPKRCRGAMRNPHAVLLSGFRSLGATSSHFHTALEKIRFNEELVTQSEATFFSKVV
LAFLKAFNIQTRSKDVEIVVVDPATQIQKKECVNVELFQKELARCVKLYRGFVSPDTPIHEKLMALKDEQLFELLFKHVA
EAHTLVKQLAGLDEYYKTVRSDVRAKIKGVKIEVTTITTSVTKANKCRAEYASQLEEQKHMKRLGVARA
>SEQF2545_AGK84232.1 oligopeptide ABC superfamily ATP binding cassette transporter, membrane/binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRRMRLSRRGILTVVGTLLLLPLFPSEKKKTHAPLPRSERKEFVVSFSPYRPVLHPHVASRVDEAQLLTALYEGLVTYDP
YDLHPIPALAQHWSVSTDGLTWTFYLRDQIFFQNGDPITAETFQQSWLNLLNPEWNVPYASFLDAVEGARAYRSGTTADS
HTVGILVEGSDKKTLVVKLAYPAGHFIQMLCHHAFAAVHPTQLASVGTLHARTASASAHKPFHPIASGPFELQQMQADRV
VLRVNTRYWDRDALALHAIVALIAQDPAARDAGFNDGSIHWISGALEHSSLQDAATLQIVPLLATEYLCFKTAHEPTCNA
TLRKALLLATPVEELTARYLFPARTLVTPFTGYPVPPVVHEYNPARARALLAEAKIGGETARTPLKILVSDTEACRALAL
ELQKAWTALALAVEIWAVRPETYREYVQDEKYHVRIVSWVADFADPMAFLELFRKGSKTHSTGWTHEEFEALLTRAGAEP
HVLRRWELLAQAERILLQEAVVLPLSRLHALHAVQRRTVRGWYANVLDVHPFKFISLQEEIKVNLDS
>SEQF2545_AGK84233.1 leucine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGYPFRALEKKWQAYWRDKRVFCVSEDERFPPERRAYVLDMFPYPSAQGLHVGHPEGYTATDIYCRYLRMGGYNVLHPMG
FDAFGLPAENFALKTGTHPRVSTSANCDTFRRQIQSFGFSYDWEREISTADPEYYRWTQWLFLKLYEKGLAYEATAPINW
CPSCKTGLANEEVRDACCERCGAEVTRRGVRQWMVRITAYAERLLSDLDELDWPESVKQMQRNWIGKSCGAEIDFPVDAP
ACSVHDKLPQTIRVYTTRADTLFGVTYLVLAPEHEAVTALTTHAQRAAVQAYVQRAAKKNDLERTDLAKEKTGVFTGAYV
RNPINDMRIPVWVGDYVLVSYGTGAVMAVPAHDQRDWDFATRFGLPKLTVVSADYTATVPNSNSPQGTVLQRCVSDEGFV
VNSGAFNGLASADARERIVAHLEMRGAGARRVTYRLRDWVFSRQRYWGEPIPLVHCPSCGVVPLPESALPLLLPETADFT
PTEDGQGPLARACTWLRVPCPQCASDAVRETNTMPQWAGSCWYYLRYMDPRNKTAFCAPEKERYWAPVALYVGGAEHAVL
HLLYARFWHKVLYDLGLVSTKEPFARLVNQGMITSYAYRRKNGALVPHDEVHTNAQGTYVHARTGEKLECVVAKMSKALK
NVVNPDDMIAAYGADACRVYEMFMGPLEASKPWNTQGLVGVFRFLEKIWVLAGRVAAANGIPQDSRAEPPGDLHAQKKSC
SMYALETLLHRTIQKVTDDTSALSFNTAISQMMIFVNEATRVARRMPLPSKMWEMFVKILSPYAPHLAEELWEMCGHTHT
IAYEPWPQVDPARVAPHVCSVVVQVNGKVRDTFSVAPNAPNEELEQKARETAGARKFLGTQQPKRVVIVPNKLVNFVL
>SEQF2545_AGK84234.1 DNA-directed DNA polymerase III delta subunit [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSVWLFTGPEIGERDSAVQEVCARAQAQGTVDVHRLYAHETPVADLVDLLRTRALFADAVCVVLYNAEVIKKCDEVHVLT
EWIKDGGSRADVFLVLISDSVSIHKRIEQNISPVHKRVFWELFENKKHAWVQRFFFQHEMRIEQEAIESLLELVENNTRA
LKTVCTQLSLFFEKGRRITAHDISSLLVHTKEETSFTLFDALSKRDLEHSLMILNTLLCSKDVAPVQILAGLAYAFRRLA
HWHHIPEDKTHPATLKRYGFTSRRMIAQYQRAASLWTLSDTHAILDRLFQTDAMIRSGGTPLQGPLMQLCLYAIVVHAGR
APHRYCTTLQEQCGLQNEIY
>SEQF2545_AGK84235.1 HPr family phosphotransferase system protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVVKTVRVLNRAGVHARPAALIVQAASRFDSKIMLVRDTIRVNAKSIMGVMAMAAGCGSELELVVEGPDEVAALSAIERL
FQNKFEEE
>SEQF2545_AGK84236.1 bifunctional Hpr kinase/phosphatase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGAPLFTVLDVLKLDLKERDSLDLRCIAGHHGLANPITISDLNRPGLVLSGFFDLFAYRRIQLFGRGEHAYLLALLEQGR
YGAIEKMFTFDLPCCIFSHGITPPEKFLHLAEPSSCPILVTRLTSSELSLRLMRVLSNIFAPTIALHGVLVEVYGVGILI
SGDSGVGKSETALELIERGHRLVADDLVEISCVNGNSLIGRGVHKSIGHHMEIRGLGIINITQLYGVGSIRERKEIQMVV
QLEEWNSSKAYDRLGTQELNTTILDVSVPLIEIPVRPGRNIPIILETAAMNERLKRMGYFSAKEFNQSVLKLMEQNAAHA
PYYRPDDTY
>SEQF2545_AGK84237.1 hypothetical protein TPFB_0591a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVTCDTTQIKRIALFQIELEHIENGKKRSTHGRYCSTKARTRKRAHRSESLSSREPQVRTGTLDFYIQLVSADGARVWGT
RSISSAERAAAS
>SEQF2545_AGK84238.1 hypothetical protein TPFB_0592 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVFRRTVALALLLRTLPCAAHFGNRDRTFYDLNNAPLALRAIQDAYPHLNAVIAYDPREQDWLIRSDGRTLYWAEGRLLP
REHRDQAHDWRPIIDYVYAREVLDPAHLFPEEIHALRPKTLAIKRSATKPYHDAFFTWLYGPATRSEINARLARDYTFLG
KPVYVHKALITRLNAVQEKILTAAKTHAHVQKFIEDLLRVDGFNWREISDSRQKSNHSWGIALDLMPKNWQRHTMYWNWE
AAHNEDWMHIPIKKRWAPPAEIISLFESEGFIWGGHWMLWDTMHFEYRPELLAVRKILAEGNRYDFQEQNIVVHADDFPA
QYFSPKEVFGTDEKEHITYAESCVRATHASVKELVRARTLVARFSPMRRLHVYAPPESIHNSIDTALLRMTAQLKKNYTN
AKIRNNSRLLSKKHAQTRASRRSADVYTVSCRHAQAIALQYPHALSWQSKERSDALWIALFSVRQEAARRSVCTPSSKEQ
CMTHALSSCVDLARTHILLP
>SEQF2545_AGK84239.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHDARTFFMRGSCTYAHPVAIGRFFPLSSPTHTPQGTLMKSHGTMCSRNALLLPRRGAGLHVLTPRIREARPVNTGVKVI
LSLFATLVLMVGVFFCAPRASFAEFERHFYQPTVLSALSTNLREVSKASEAWHSRYRPLFSQFCALDAVRSSFDPAQKAE
DITQRAREASALLSSVAGLKGVRIVEAQKPNIHFSTFESDVLLADSGSVTYRKYNAEEHDVPLQFLGEHSPEPKVIVDEY
HDALLYSFPSLGNYGEYRGRILFYLSLRALGTHLIAENKLKITDSIVPLSADDYTFGGIVIGIPHEGVRSLKPSVLAEWK
RKQFRVQTVRSEQHEDWALLSNASGAFVIAQAVPVLLFGFTPLTKGLVAMVAVVTTFLLVFQLLSLRQDPLTKLRDRLIH
FHAQLLHSCLEQKESLEWEEVRTRLEHRRRETDAEMKKSLPRRLRIRRGRELDALLSKGWDDVFSTLEHGYGGARAMNRA
QIEQLVREVLAQSLASGEAVLPVAMRADTADEELDEVLEELPDEAASLPSDSSPEEDLDPLEEVESIEGTAEESTREYAA
AGDALLSKTPQLSTHSEYVPATLAELLGRNAEPGDVVRDSAVLEYIEGVFDYRPCCFYESHAVHDCLEVVTGEDGPSLSP
MESIVSTEDGLFTIRVSKEEGNHLNRDFKALVDSVLY
>SEQF2545_AGK84240.1 hypothetical protein TPFB_0594 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVPAFLQVVFPLVGCAHYILWGRAMRKVIVYGVVLCLCVPCFTASSDKAAQVPSVQKEMADPVEGIWKSVDDNTGKPTGV
WRLYVQDGKLFGKILVCMGRAPNAAVVSCTRTYPDFPKKGNVANMPLVGTPFIYNLERTSPGSWGGGYVIDPASGKYYYC
KINFIPADGRSYKVDTLQMRGEISWGIGRSQYWLRSSQTEVDELIKTNVVAHTFVPASE
>SEQF2545_AGK84241.1 adenylate kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRFVFLGPPGAGKGTLAGEISGRCGVVHISTGGILRAAIQKQTALGKKVQKVVEVGGLVDDQTVTELVRERVSHEDVVSG
FILDGFPRTVTQARCLEDIVPIDYAVSIVVPDDVLVARLTGRRVCSACGSSYHVLFAQPKREGVCDRCRGVLVVREDDKM
SAILQRLTAYRAQAEPIVHFYSERGKLVSLNGAPPISDVVLEFQERFAQSR
>SEQF2545_AGK84242.1 tRNA polynucleotide adenylyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLVRYSYDAKGRRLGRALVYTESEHGIPRQSVDAGAIRVVEALVGAGYETYIVGGAVRDLVAGRTPKDFDIVTGAVPSRI
RRLFRNSRIIGRRFRIVHVSCGSQLYEVSTFRSRVGEGSVCVPGTLEEDAWRRDFSVNALYYDPLRNVVIDCVGGMVDLK
RRRVRPLIPLRSIFVEDPVRMLRALKCSVMCESSIPFSVRRSIRRSVSLLGGCSPSRLTDEFVKILFSGRSAALVRALCG
YQLLLYLQPSVHYFMRDVPCFESAFFASLRVLDQAFVSGRVKRVGQALTYVLRDFVGLVFGHADAPDEVYIRVYRACRSF
VLPMDPPRVELEYAVRSCLGGRGFAARAACTPSGRLCARENGVRCVFSSP
>SEQF2545_AGK84243.1 hypothetical protein TPFB_0597 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRRCMLGRIFHTRMFLLTRSARTASSIWCAWCMGCCTLGLFADSVEKRAAKDVFTEPARFYPSQKSTLESARSDTSESEN
ASSSVPSHSQQELAPDSAAPARNSVLSPAPPERREKQGTAVHGAEVTRAGAVSPRFVGGLTKILAASDHTFFAAGNDGFL
TQYTYPDYKPDTWQITPVSIKHCAVHPDRARIAVYETDGRNYHRVSVWNWRTKEILFAKRFTASVVSLSWIVQGSFLSVG
TASREGVTVLDGSGNTVSLFSEEPGVVLLTASGPRLVLSYAESGRLTYVDYSKKTTVKRLLTEKNLLSPMLIHNGAHLVG
YRDQRVYVIQSSSGAVLTEYPARSACFAHTFSDSLPVWIEPAELKYHWRIRKAAQRSADFMLPDNARITSACSVRTRVIV
GTDRGILYELQQGDDRRVTIRALNGERQIYASDVHGADEGAYFLADGSLYHSMASGGPYRVLVRGVKGTRFLPYRDGFIV
WSAGKETEFLHCAQKTSQHRMIYRARSTVSGVSVYGRMLVITEPFSGVSVVDIERGIRVFFHKAIGMQDSLLITDDVIVA
TQSGLQPLVLLHMRTGETYTHAVGGDFAFGVRAHDTQHVYFFSLDTNAGTTDLIHLRLQLQQPTESVVRRILSYKDEDID
AHMVMRRSLLVTNLGKGALVGHRVQQSQVYRMSRAYALPKVAAITSNGVVSVNYDGSVSWYEGDGATLKATEFIRTEDF
>SEQF2545_AGK84244.1 hypothetical protein TPFB_0599 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQLRCACERVFDIEHETVISLDEHPEFVARIQQGDFLSYQCPACGARIRAEIKTEFVWHAKNVHLLLVPERERLRCLAFC
AGMHMSDGDSADFCEPFVLREHQTPVIGYAELADRVAILAWDLNPEIVEAVKFFVLEGAPHLGDKRVSCFFERCVGDTGS
RVMELHVYGIREQQTAIMPVPMNVYERVERERGKQAELFEALYVGAYLSYKNVFTDA
>SEQF2545_AGK84245.1 putative membrane-associated zinc protease [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIKIIIGVVVLGIVVLFHELGHFVAALWCRVEVLSFSVGMGPVLFRKKFGKTEYRLSMLPLGGYCGMKGEQAFQTALDQK
LSRIPVEPGSLYAVGPLKRMGIAFAGPLANVLMAVMVLALVSALGSRVHTFGNRISPVYVYDSSDNSPARRVGLQDGDTI
LRIGDQPIRYFSDIQKIVSQHAQRALPFVIERRGQLMHVTITPDRDAHTGMGRIGIYHYVPLVVAAVDAHGAASRAGLEP
EDKILAVAGRRVQHAVQLLALLKEFRKKSVVLTVLRSGKRRYHTIALVRTENGAIDVGIEWKAHTVVIPGTSFFASVRAG
IAETLRMCVLTVKGIGMLFRGLQFQQAISGPLRITHVIGDVAQHGFQESFLTGLSQLCEFVALVCVSLFIMNLLPIPILD
GGLILFACVELFMQRSIHPRVLYYLQFVGFAFVALIFLCAFWNDVNFLFH
>SEQF2545_AGK84246.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSVRRVVVLGITGSIGAAALKLLRRFPDRFLLVGASGHRQTEYARALAREFSLSDITMTGSCSEQEGRARIKRLLSSCEA
EVVVNGIAGAAGLFASLEVLKTRCTLALANKESVVLAASLLHAAARESGATIVPVDSEHAAIFQLIAAHGAHAVAQVVLT
ASGGPFRTFSKECLAHVTVEDALQHPTWRMGKKISVDSATLANKALEVIEAVQFFRIPVDRVTVVVHPQSIVHALVQCHS
GETYAQLSVPDMASPLLYALLYPDAPPAYQTPLDFTSGLSLHFEPPRVDDFPLLRMGFDVARAQRAYPIAFNAANEEAVR
AFLQRNIGFLDIAHVTAQALQEDWRAIPQTFEEVMACDTRARMCARTCIAQRWRER
>SEQF2545_AGK84247.1 phosphatidate cytidylyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSAEIKRLLIFFFGVPTILMLVYAAPHAHFLAFHLVIFGSVMGAVWEMHAMVSRRMCTYPLVLLIPFSLVLPLLGYAALW
QPARGAESVLFIGALGTLLMSVFFTELVYSFSASFENALERMASALLLVLYPGIFSLFFSLITRWRHAEIALVIFFLMVF
TCDSCAWFCGTLWGVNNRGIIPASPKKSIAGFIGGFAGSVGAGCFGSLVFGSRVTLSLGMLMGVGALVGLTAIVGDLVES
VMKRSAQVKDSGFFTPGRGGIMDNLDSLAPSLGTFYIACECFGIAAV
>SEQF2545_AGK84248.1 di-trans,poly-cis-decaprenylcistransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQHVAIIMDGNGRWAERRGLRRSAGHRRGLQTAREIVAALCAIRVPFVTLYVFSTENWKRSAHEVHFLMNLIRWYLKKEM
SFYVEHAIRVVHLGCAQTLPPDVRSQIEYVVERTRSHRGTTVALAINYGGKDEILRAVKKVLCSTSCPDGELLTEEAFGA
CLDAPQLPSVDFLIRTGGQQRMSNFLLWQSAYAEFYFTDILWPDFRVEDMLRALDEYRLRTRTFGGLE
>SEQF2545_AGK84249.1 ribosome recycling factor [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGIAECYEQKMKKSLSALQEGFNTLRTERATAHLLDQITVDYYQQPTALSQVATVSVPEARLIIIQPWDKTLLADIERAI
LKSKLSLNPSNDGKVIRLVIPPLTQERRKELVRQARALAEQARVAIRNIRREGIEEAKRGHKEGLLSEDALKAAEEAFQK
ATDASVADVARYLAEKEKDILEG
>SEQF2545_AGK84250.1 elongation factor EF1B [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEIAARDVKSLRDKTGAGMMECKRALQECAGDALCAEKYLKERGLAAIENRRGRATAEGVIVIKARHAEGAACGASAVAM
VELVCETDFVAKNAEFIALAERIAQAVLEHAYTEVNQVLRDMVVDLATRVRENMSLTRLALLRAGSAGAGQYLSHYVHPD
KKTGVVLSFSSDAPDVFLRSDVRAFAYDCCLHAAAYTPRYVRAEDVPAEYVREQREVFQAHVASLQKPAHVKESIVQGKL
EKHLAEICFLKQPFVKDDKLSVEKKMAEVGARAGGALRFTQALIYQLGVQ
>SEQF2545_AGK84251.1 ribosomal protein S2 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVVTIKNLLESGVHFGHQVRRWDPRMKKYIFAERNGIHIIDLQKTITAIREAYDMVRRTVSSGKSVLFVGTKKQSQQTI
AKEAQRCGMFYVTNRWLGGMLTNFSTIRKSLSRLKKIERMEIDGTFEHLSKKEVASLRKEHAKLEKNLGGIKEMKELPGV
VFIIDTRKETIAIREARRVGIPIVAVVDTNCNPEGIDYPIPGNDDAIRAISLFTQLIANAVMEAGNEHGLKIIENLQDEE
SGDELDESVSLHEEGREITDYENYTPPEEREYSVNDEGDVFDEDESLYEGR
>SEQF2545_AGK84252.1 hypothetical protein TPFB_0608 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQQRFFLLGVCAFAFGVPVFPQQGTDPSVGAQASAGDGGMMTVEQAYLNSAEGVVIKEMVESRGHDSKVLALQYIQEALE
GGRGSDDLQEALSRLATAGLFRVIREQGRVINDFPDIRLRACELLARLPSARTKDALIQVMCADREPSVVRAAVKSLGEV
GINEQDETTATIGWISRKFSAINPTGSLALEILNTYERLAPTVRDRRAVVESIMDIAADGRYAAAVRARALEVVKGVVSG
GK
>SEQF2545_AGK84253.1 hypothetical protein TPFB_0608a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MERVHLWSLIGAVIVHPRVLSAGVFLILYLHLVFYVVRRGPGHRRPRLGRSSSRE
>SEQF2545_AGK84254.1 asparagine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRAMHPLLKEILTHPPSGQHECVHGWVRSKRETKCAVFISLSDGSCPDTLQVTVPLPECSASLSSGAQAEQIPNVRDAVL
QGETLAQTLKRVTTGACIRAEGALVPSPGAGQALELRACNLTVLGEAPAETYPLQKKSHSFEFLRAHAHLRARTSTFAAC
ARVRSALAGAVHRFFSERHFQYVHTPIITASDCEGAGELFRVTTFDPVRIAREAHAAGAAGNPYALTYADDFFGKAARLT
VSGQLQGEAYALALTRIYTFGPTFRAENSNTSRHLSEFWMVEPEIAFARITDCMDVAEEFLAYLLRAALKDCAQDIAFLD
ERAAQHARSARGDTPLAARSTARTPPVRTPGQLTRMLEDVARAPATRLTYTEAIKLLENSGRSFEFPVRWGCDLQSEHEC
FLTEEVFHGPVIVYDYPKEIKAFYMKLNADGTTVRSMDLLVPGLGEIMGGSEREEQFEVLCARIRASGFDPHDYRWYTDL
RRFGTAPHAGFGLGFERLLQYVTGLGNIRDVIPFPRTPRTADF
>SEQF2545_AGK84255.1 Tpr protein H [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKGVRCPCLYACRVLYSQSKIRRRRTLLSPSAAVRSSCHDPPGHSAGRRVRSVGTWALLFMSSAAGLCGETRLHTLASTP
RISGFARLQWGITLPYDPAVGPPPPVPPRENGDGDDSDVVNVQIQGNGAQGQEVEESEKEKARIRQITHGFRSTTHLCVT
VPLFLKSDRIRRAGTLSDGGLWTEISIKDLEVNFQTKKPGEPFTLVTEETAIEATLHCFGAYMTIGTAPLFRANFAQLWK
PFLADLYKEEEVRFAPGFDGIGGRLGYRAQNVGSSGVSLDICFLSFASNGSWDAPAPAPAPPGGAAEEALHSKYGFGADA
TLSYAPWKRELVRAEVAASATLGKGYKRVSHKQKRHYRQNDVLWNAGARITLTPLSDFKVVLALDMGNHYAGRKTLDYLA
PILIDMEKTKVTPGGPVAYAIAQRVLQLPEYAQKLDSVKNGMSANGSSVRDIATKIVQAEQTNPTVSSNPLLAALLTVLW
QQALDTYALDALLTLQWRWFACGVYVATAPASVFGAMVFPTYGSTHMDGGGFLRVETKAGDAYTHLIDGLEAGMDVRCYI
PLTHGLYIDNGKGYYVSPMGVWKLPDTHINLPVMGKVWARYLIPLGETAWLKPSLAVYGTTNRFNYNLKTENLVHERCVQ
YQVGLTLSPIEKVTLHAQWEQGQLEPTPYMVITETVTSRRYFGTFVCGMTINW
>SEQF2545_AGK84256.1 ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPTLLDIRDLCMSIADRPILKSLNLTLNTGEVHAVMGPNGAGKSTLAGTIVGNPHCTIERGEIYFQGQCINDVPVYERAR
RGIFLSFQTPEEVPGLSVEEFLRAAKEAVLGTKVSVLDFHTQLRAKLARLRISEAYASRGLNVGFSGGEKKKNEILQLAV
LEPKLAILDETDSGLDVDATRIVFEGIDDIRTPDMGFLIITHHREVLEYIKPDVVHILVDGTIVKTGDVSLVHYVVEHGY
ADFATPRAGEQGGTPVSPE
>SEQF2545_AGK84257.1 ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNTQQQRQLLQPRRRTYVSDIKRGIYDVKDAVTYTYSTGKGLNAQVVEKISRRKREPQWMLDLRLRSLRYFMKRPMPEWG
ADISDLDIQEIVHYIVSDFKPIAESWDDVPEEIKKTFDRLGIPEAERRSLAGVGAQYDSEVVYHNLRADLEQQGVVYLDM
ESAVHKHEDIVRAHFMHLIKPNEHKFAALHGAVWSGGSFVYVPKGVQVDLPLQSYFRLNANQSGQFEHTLIIVDEGASLH
FIEGCSAPKYYKNALHAGAVELYVKKNARLRYSTIENWSRNLYNLNTKRAIVDEDGVIEWISGSFGSRVTMLYPMSILRG
DRSRSEFTGITFASAGQYLDTGTKTVHLGRNTVSEVHARSISKNGGTANYRGLLSIGPKADGAKAVAECESLMLDNQSHT
DTIPIIDVRTDNVDIGHEAKIGRISDRVVFYLMQRGLDEQTAISLIVRGFVEPVSKELPLEYAVELNNLISIELEGAIG
>SEQF2545_AGK84258.1 ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKREFFKRLGYHAQDVASQPFSRTQVTSSSALVRSSSIEHFLCTEPERAARAFDFRTRDRQRHCGLGEAYVQEVKEKRN
AGVYLSVPRTSETVHVLIRFTMDTHNRVLYDQTFLDIQEGARVKVLVCVDAQGYTPQDAPALVGPQALERAPFRNGLVSV
QVGRGASVELIKVQNTHPTAVNFETVHLHAQESAQVRCYDVQIGAQISGVSNSAFLRDEWARVEIHPLYFIDKARRMDLE
HNLIVEGKNSHAHICACGVVKDGARKTFRGNIFLHRGCSHSVARFSDRTILLDRTAVGVSIPTIFCDEDDVVGEHAASFE
TIGSDVLYYLMSRGLDEYGAKRLIIEAAFKPVFALIDDAHIRETLVRNFDESLDRAHRKRKA
>SEQF2545_AGK84259.1 bifunctional cysteine desulfurase/ selenocysteine lyase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSGPNYKADFPLLLRSPRVHYLDSAATTQRPAPVLERVMHYHTHLNGNAGRGSHELAVESALLIENTRKKTAQFINAAPT
HDIVFTKSCTESLNIIAHCYALPRLRAGDEIVLAISNHHANIVPWQHVCRCTGATIQWLYPDAEGNLDIQEAQKKIRACT
KIVSFSAVVNATGAVNPAQELTALAHQVGAVVVIDGAQAMVHGVPNVADLGCDFFVFSGHKMFSLFGVGVLCAPHTLLES
MPPFLYGGGMVDFVTEQESVFKGAPHKYEGGSANTAAVVSLCAAIEYCESLESSAVRASVHALDAALLARLEELPFLETY
HARARERLGIIAFNVKNVHSHDTAHILGEEGVMVRSGDHCSKPFMTHLSIQSCCRASFCIYNTMEDVEALTRALHAVGRI
FQCS
>SEQF2545_AGK84260.1 SUF system FeS assembly protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNAEAIYRQVLLEYARKQEHRRVLEGPVGIERGHNPSCGDDLTLLIKREGDRIADVAFLGTGCAVSTASTNILIELIKGA
SVAQAQKTVALFFHMMAQQCLTDQERAHLQDACILACFASMPARIKCATLSWHNADILLHHKKDTDA
>SEQF2545_AGK84261.1 ribose 5-phosphate isomerase A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSALVEKAMHERNTTTNTPLDVTAQKLLVAQRSVDTLVQEGVLHAHMSIGLGTGSTAMPAVKRIADHLARGTLSDIAAVP
TSFQTALICERYNIPLFSLSSKRIGGKLDVTIDGADEIDTQNFVIKGGGAALLQEKIAAYNSAHFVIIVDETKVVETLGT
RAALPIEVVPEARMSVMRTLQDWGLSVHIREAVRKKGPVVTDHGNFILDARWQSLPTRTPQDMERALNALPGVIENGLFT
ERTVRVFVAHADGSVEERSASF
>SEQF2545_AGK84262.1 hypothetical protein TPFB_0617 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCSFEHGGWYVPKTVLSLLRRRKCQDARAESEELGITGICQNYAVPVQLGVQHYFGAHWGIDATATVSFGVDTKLAKFRI
PYTLRVGPVFRT
>SEQF2545_AGK84263.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MWRKCLGKVVLLGCALPCVAARISVSPKLGAYGDARGGPDLWGLCIKATDAEEVSGDPDDTEMEYLPPRYAPETPLVGLD
VAFRAENGFLLQLTVDAALTRLMFCGRCLAGYSFRPGGGKYVSVGSGGF
>SEQF2545_AGK84264.1 hypothetical protein TPFB_0619 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRGCRVGQRTGTVGVRVFPVGLCALSLQARDCRGMGRRSVWGVLMFGCMLPGAAARVSLSPKLGVYGDARGGSDLWGIC
IQAPTMPDTENQAPPRYAPETPLVGLDVAFRAENGFLLQLTVDAALTRLMFCGRCLAGYSFRPGEGSTHLSVAAGFECTA
LIYNGQHYLIVPKAGILPKSTSGCTEGGWRLPRSVLGLLTHQKDEGAIHEESSLEGICQNYAVPVQLGVQHYFGAHWGID
ATATVSFGIDTKLAKFRIPYTLRVGPVFRT
>SEQF2545_AGK84265.1 Tpr protein I [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRQVMQAGVLAGMVCAASGYAGVLTPQVSGTAQLQWGIAFQKNPHTVPGEHTHGFRTTNSLTISLPLVSKHTHTRRGEA
RSGVWAQLQLKDLAVELASSKSSTALSFTKPTASFQATLHCYGAYLTVGTSPSCVVNFAQLWKPFVTRAYSEKDTRYAPG
FSGSGAKLGYQAHNVGNSGVDVDIGFLSFLSNGAWDSTDATHSKYGFGADATLSYGVDRQRLLTLELAGNATLEQHYRKG
TEDSTNENKTALLWGVGGRLTLEPGAGFRFSFALDAGNQHQSDADADCRLPATGSSREKFDRAFDALRVEQYYVKDKYLE
FLLGQMAESSILERVGLALTLQDGTLVSTLTKVATDSGDQFIQMALVKLLPQRAQAEQGLREIVAPSQSDIVLIMLLTWL
ERARLDRFNADALLTAQWTYVSAGLYGATAGTNVFGKRVLPALQSWHFDFAGFLKLETKSGDPYTHLLTGLNAGVEARVY
IPLTYIRYRNNGGYLLDGVVPPGTINMPILGKAWCSYRIPLGSHAWLTPHTSVLGTTNRFNVINPAYTLLNERALQYQVG
LTFSPFEKVELSAQWEQGVLADAPYMGIAESMWSERYFGTFICGVKVVW
>SEQF2545_AGK84266.1 Tpr protein J [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGCMRWGSVLCVVVGVGASGGVLGQEFSPKLTGSATLEWGISYGKGVGSHGQAPGAVMGTGPYNLKHGFRTTNTVGVSFP
LVMRTTHTRRGQHPALYAELKVADLQADLSQGKAGFAVKRKGKVEATLHCYGAYLTIGKNPTFLTNFARLWKPWVTAQYQ
EDAVQYAPGFGGLGGKVGYRAQDIGGSGVSLDVGFLSFASNGAWDSTDPTHSKYGFGADLKLMYARAGHPLCTVELASNV
TLEDGYLIGAQKDANNQNKDKLLWNVGGRLTLEPGAGFRFSFALDAGNQHQSAQDFQNRTQRAQSELTALSNNLFQGESQ
KQEAWLDEYAKKVLDAVTAATETALQSRGNAYITAVSNVKVTPPVAATLLTNLKVFITDPPTPSPLPALPAFSLMGQVLL
QYDAEQVVKGFEQVQTQIVAEINQKVQAAVAQSKAAAQAFINGLTKAIEDVADALLAPHKGNPMSLFNLPDQQKLLKDDL
ADLIPKLTAEATKFFTEGQTFVTEEVKKKTDALDAGQQIRQAIQNLRASAWRAFLMGVSAVCLYLDTYNVAFDALLTAQW
KWLSSGIYFATAPANVFGTRVLDNTIASCGDFAGFLKLETKSGDPYTHLLTGLDAGVETRVYIPLTHDLYKNNNGNPLPS
GGSSGHIGLPVVGKAWCSYRIPVQDYGWVKPSVTVHASTNRAHLNAPAAGGAVGATYLTKEYCAQLRAGVSASLIEKTVF
SLDWEQGMLSDVPYLLVSECLTQGIGRIVCGVTLSW
>SEQF2545_AGK84267.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGALTKSIDRAIGVSVGFVLIPVFLCCRSSSKVVPTRAGTDPVSSASQAPEVAAHPVRGTALDVPDRRAIRTKLMDPKIL
FLIETASPASLREAAACIQRDPAGLTPHNRLYLRVCAALMQLVYPQEAVSWHVPLYNTAHPYLTALDDVEKGTYPLIPGE
PDFFSDIIPPLTLLKKRLPDEVHADCRERLTRARTQAPHSLLPFLLFGYLHEQHGELSEAESAYRSAWEKDASCYPAGIC
YARMLVQRGETALALPIARLLLHRFPKDRAVQLLQAQIHSARQEWSAAQPYVAALLRQQPEDNAALLLHIRILVAQREYQ
KAHASLDSFAERDSSDKTYLLLRAQVAKEWSKNDASAHDFLQQAYRLYPRDVQVLLACAQHCFETGHSLAQKNMRSFIAL
VLRADAHNAQALRLLTQYELAQGNWEQAVSRAERLNTAYPSEAHQELLIRAYSGSGRAQEAISLARRLYHSAQPPSETVI
VLYLDTLYEARHYREIRAVIAARSASARGTLRSIFSYYEALLSVHEEERLSLLRASLLSDPRNGRTLFALYEWYRKKKDF
RKAQYYLHQVIALDPNNAQHRALSKQLDTLIGQ
>SEQF2545_AGK84268.1 membrane-bound lytic murein transglycosylase D [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARSMLLVSAPIEIRFYLPAWQSCHLHKTPVVTVPTTYAYPAHRRFFSLYAVFNAHGASLVLPTQDMLGWLPPRAKRAYR
RLTVFLREIITARACSLFLFLLRCFPAGPCARARRLSFLLFLCGAAACPPLWGAYAAHHALRAQSVPDTLIQRALVLGPL
VHPLYPPMQSFKEQYRSARYREYLSVVMQRSAPYRPFIEKLLRDAHLPVELLFLPVVESGFLERAVSKSGAVGIWQFMRN
SIAGSAMRVSDWVDERRDPWKASVAAVKKLQWNYTQLRDWPLALAAYNCGLGAIKRAIAQAGTADFWHLSERGFLRDETV
RYVPKFLAVAEVLSRSHEHGIAWGAAHTPEETTTVTVSRAVDLNLLAQAAGMDAQLLHTLNPALRYSITPPNAAYTLRVP
STHAQAVQAVLNRPGAVLVHHTLHTIRSGDTLYALARRYGLGVDTLKAHNRAHSATHLKIGQKLIIPTIRTGQTRRAPLR
GAGTRAPGVMDQKEHAVPEVSALPSSSMTPPTPGGADTRAGADAPAPPSVPPPPESTAARATPAAPFVGKHVVQQGDTLW
SLAKRYGVSVENLAEENNLAVDATLSLGMILKTPRR
>SEQF2545_AGK84269.1 OOP family OmpA-OmpF porin [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGVSCLTRAASFSNQCRFPFGALSLVWTHASAPHVVRSSARRFILLLLFVLFSHAPSGAQTQDAVHTDAVQDWKNGTINA
QLTLDLARARMRLPADRTAASQFLRYKAPAQLKDVYLSVLVDSQNRVGDCLAHEKIRLADITALVDAGHHAVTTLSPSVR
SLQLSHQTPLTALARLFVTHETAYVPAIPPTSAVSRPYTGILIDARGSLPVHGEYVSEPLSACLFPKIWSTDMDLIYEKN
MVHPDRAKAWGVVRYGSVWDEKMYRDRIGTTPLKIIARGVFGQQRTDPIIASKDAAQILARPENLRLLAEGNVIILCDEA
ALRVHVPYPLVDEHFYFAYHDVKRFLTDERSPGVGVRSGINTLKITVYDVRFVANSPEILASEKDRVDVIATALKKMGPY
TRFLIEGHTADLHRPQEEAALSVARAQRMAQELSRRGIEMTRITTAGHGATKPIAPSDTHANKAKNRRVEITILRD
>SEQF2545_AGK84270.1 hypothetical protein TPFB_0625 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHVPRSILRAGYFSQVKRTCDDVPMAFCSQAQLKGRSTMIKPRAYALLGVFFLYACASTPREEDVPEKFTPADLMLRAQE
SYDAGNITWARFYYQTVLDRFPNNESAVISAEFELAHILVKQKSWQDAYNRLMYILKKYEAAGSARLPPAYYKLTLIDLS
RVKPHLNLETANTKATEYQKNYQEELKQRQELRQKLLQERTQKMLEALHQEETPEQDARDTAKKKTDQEEHTMRKANAPK
TKASGEAPTP
>SEQF2545_AGK84271.1 exonuclease SbcD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKILHTADLHLGKTLHEVSLFASQKKMLGDLCTLLAQDNYAALIIAGDIYDRCVPSAESVSLFSSFLQNIKRSMPRLPIY
LIPGNHDSAQRLSFAQELLKQQGVFIAQDPEESTRPHLLCHEGETVQLFLLPFLHAGAFSYLDEENTTCLIHTQSELLQE
ASRRLQRAVSLDTPSILVAHLFTQKGISCESERPFVGNAVYADPHWFDFFTYVALGHLHKCQKITERMYYSGSPLPYSFD
EANTQKVALSVEIHCNTKGFPIHVTPLPLEPLIPLRTIRDSFHALYTGDRYLLYQRDFLEITLTDPALVHNPIGLLKPRY
PGLLSIKQENAFAFDIPPPYSSNEGIAPCTHHSLRTHFDVFMHEVSPTPDDREKGALFQELFDEMQQEFSS
>SEQF2545_AGK84272.1 exonuclease SbcC [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKPMRLTLHNIGPFVGTHTVDFTALGPIFLVCGKTGSGKTTLFDAIAYALYGKPLGTRAEVIRSLRSHYAAPSEAAFATL
EFSLGTKIYRVHRTLTCTLSHRKTEQPEQLYLEQKKGHGWERIACAHKSETECVIHDLLKLNSKEFERVVMLPQGECAQF
LKANSKEKKETLMNLFPVDQYTALMERAKKKSLHAKAVLETLRSQLETLCAECMPDTYHERKQTLEAELQHARDALQQTR
ISHAYYTQKREALEAQLKKQQLCKELRARIETYRAQEPVHAETQKRIDRARKAAPLAAHIKHVTQCEQDAQRIHAEIQEK
MRSREQLLMKRAAYVAQQSSIEEQRRLLQTLHSACIHIEDAHDVATSIRDISCQAHTLTQHIHTLAQQKTTLTQQEQSLC
KELDILQREAGTIDTRTSAFNDLQIQLAHAKKTQELSQRYAELCAAHATCTAQCEKLEKIHAQKSAYSTRAREQLLQTKE
QIHLQETRTHAVVLARLLEHQEPCPVCGSCIHPNPARQDIDNLEPLTRRMQRIEQTYAQLETSEKDVYHILTSERERRAS
YSAQMQEIQHSFSILTSCDTRSSCDIPNVQKITVRVLDLTEKLSRAKDMLACAQHALLRKKQPEQDLQDVRAHLQQCSQE
LAKKETALHALQETLTQQRVRIHALSIRLPKELLASNLLAPQKMQHEKESVAYWKEMLAHCQTLMRELHTHIEEYDREFN
EIENASSALGADIAAREDALNHVQKEYMHLARTVCCARTEAHFNNNEEVTAALMTDAELSHAAAEIQFFNELRAADTHLL
KTLEAEIGTEIPSDLDELNAQCHTLVKDEENFLSRIEILSATLHTLTHQYLKYEECSKQLAQKTQESAKLITLSDELNGI
NQKKIQFDAWALISFLHEITAYANIRLQKMSEGRYHLRVADSHVNARGYQGLALLVADAYTGSVRPSATLSGGETFMASI
SLALGLADSIQTRSGGIVLDSLFIDEGFGSLDEASLDKAIGILDEIREGSRMIGIISHVHELRTRIPHKILIKKTNAGSH
VMQGDAE
>SEQF2545_AGK84273.1 nicotinate phosphoribosyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKTSALFLDFYELTMAQGYFFHKPHECAVFEVFFRKHPFAGGYSIFAGLDPLLTAIEQFRFSGEDIDYLRTLHLFHDDFL
SYLASFRFSGDIHALEEGSVIFPHEPIIRVHARLVEALLLEGLILNTINFQSLIATKTARMWRASGEGVLMEFGLRRAQG
YDGALSATRAAAIGGATGTSNTLAAKLYGIRPMGTMAHAWVMSFDSEEEAFERYAALYGSASVFLIDTYHTLESGIQNAI
AIGTRLKAAGKSFGVRLDSGDMQYLSVQVRAALDAAGLPEARIAVSNELDETIIESLVLSGAPIDAWGVGTHLVTGGADS
AFTGVYKMSARATTQPAHTQHGHAASQRLPHWDDAHWLPVMKVSDNPAKTTTPGIKQVWRLYDAAGQYKADVIGLADEVI
EPQVAQRYIHPFYNLQSFTFAAHQVEPLLRTVMQAGNRLRAGESVQEIHARMRAQLQRLDKSYVRLLNPHVYKVSLTERL
AQLKNTLITALRR
>SEQF2545_AGK84274.1 hypothetical protein TPFB_0629 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTMAGFLRGLWCVVGTSVCAQTLQEAPAHFLLEGTDFAARVLRMSISARNVPSYWFEEGVWSEAPSASSRLPAKNKSTPG
VPRRVTRALPRVKPDVFVFGNEHETVFWGQLNTIEHARYVVHRAVHPLDAHAHERYYEPLLKRFHFYCLEGRTPITSVSL
CLFALDVSTRLIWAYALPSQVEMVWGTRIPRAWIPLEMHSHVRARYPKAKFYQFDPIGFVDSEGKVVLYPWALEQHAQRP
QDFLVYEPQQGDWEQVASQTGPGHSPYRAM
>SEQF2545_AGK84275.1 protein-glutamate O-methyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTAATEKSDITRSYLTLGKGVRPMSTLSDAEFAAFKTLIYEHSGITFSALNRSVLESRIRSRLRELALPSACAYYQQVLA
SSAELSALLDSVTTNLTRFFRNKAHFDSFSHYVIPELVKAKRSVGEHSITVWSAGCSTGEEPYTIAMLLKRYAPAAFSCQ
VIASDLSLKSLLVARQGYYPRARVSGVPDEYLRAYFRETQEGYQINADIRKMVRFDYHNLKHRSMHRNVDVLFCRNVLIY
FDETAQKAVIERFWDAMSAHSFLFIGHSESLFGMNTKFSFLKTPWGCLYQKNDEGSAHECHAR
>SEQF2545_AGK84276.1 protein-glutamate methylesterase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKNTNDIAVLIVDDSALMRKVIGKVIEGAPGLSIAGKAMNGRFALDMLERVQPDVILLDLEMPHMNGLQFLEQRKRLRID
IPVIILSSIAKEGARVTMQCLELGASDFVTKPFGSESAHLRTVSRKIVDYVTAYGRRYKLLRRTRRCLAMDTPVERPAGE
EDLNCLDTQERASLPSVCARAPARDRASYTITPTEGARQTRIVPLRESGALQIIAIGVSTGGPSALRHIFAQLDADLPQP
VVVVQHMPAGFTREFAYSLNQVCALEVKEAQEGDLVRRGRVLIAPGDRHLTVERRSLATVAHINSDEPENGHRPSVDVLF
ESVARHFENGALGILMTGMGRDGAAQLARLYTEGSRTIAQDADSCIVYGMPRVACELGAVGEQVSLDDMAATINRYGKVF
ASS
>SEQF2545_AGK84277.1 tryptophan--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLRVLTGDRPTGRLHLGHYAGSLGTRLRIQSEHECFFIIADLHTLTTRHGRAQLAELPALVRELVLDYLACGIDAQRAVI
YLQSAVPEVTELAFIFANLVTVPRLQRIPSLKEMAQAANLSELPFGLLGYPVLQAADILLARAHLVPVGKDNESHVELTR
EVAKRFNRLYGEVFPLPRALLSDCATLVGTDGQAKMSKSLGNAIFLSDDEETVRRKVRAMYTDPARTRADIPGRVEGNPV
FAYHDAFNPNTDEVAHFKERYRAGRVGDTEVKDALARALNTFLEPIRARRAQLEQQPAYLARVLEEGCARMRAEARKTMQ
RVKEAMGLSARPLVHLP
>SEQF2545_AGK84278.1 bifunctional peptide-methionine (S)-S-oxide reductase/peptide-methionine (R)-S-oxide reductase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLANLQHLSDIQYRVTQQSATETPFKNEFWNSYQPGFYLDVVSGELLFLSEDKFDSGCGWPSFSAPADARAVIEKEDRTH
NMLRTEVRSRNANSHLGHVFKDGPPERGGLRYCINSAALRFVAREEGTALFAAGCFWGTEAYFRRVKGVLRVRVGYTGGT
TKSPTYRNVCTGTTGHAEAVEILFDPQVISYEDLLKHFFRMHDPTSLNKQGGDVGTQYRSAIFYLSGTQKQQAETLMGRY
AGAGKFTRPLVTTLEEARDFYPAEEYHQDYLTKNPGGYCHVSLHLASEPLE
>SEQF2545_AGK84279.1 DNA ligase (NAD(+)) [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSTAQRRVQELEKLILHHQDRYYNAESDISDDAFDALWEELARLDPGNPLLKAIGSDSQRDAVKKRHIVPMGSQHKAADE
ESFSAWAKKNALQAFLVQHKLDGVSLELQYERGHFCCALTRGNGIVGDDVTANVRGMRGFVPTLTAEWGPCGNLPFTGGV
RGEVIMHKDIHRSHYPTHANCRNTVNGILKRKDGRGRTHLHIVCYDAVPGTPGKPFTGSLPFADETEKLAWLARQGFVTV
HSHRCANAQEVVALRSEIMRTRELLPYSIDGLVVKSTDLDFQDAQLPRPKKQIAFKFSTQEAITTLRDVQWQTSGVTYTP
IGITDPVRLAGTTVKRANLCNPNMLTKLCLKIGSHVLISKRGEIIPKIEALVSTPAHAQEIHIPTQCTSCNTVLENSGSR
LFCPNVNCPLLSHHRITRWIECLEIKHVGTELIQRLFEEKKVRRIPDLYTLTCEDLIEIEHVGNATAKKILEAIHHKKEI
ALQTFIAGFGIEGIGETMGEKLICAGFDTLEKVLHATTETLESIYQFGTELAKSVVTGIARVKDDMCELLDRGFVRILAK
QQAESPLRGKSFCFSGSLRNGDRATIHRIRALGGVVRTSVTRDLSYLIFESLSQPYRTAQKLKKEQGVALEIISEDEFCR
LLDQASASCTHTGETVHPLQGKSFYFSGASRSMNHKHAQEKVRALGGDVASSVTAQLDYLVFYSQSTRYRTACALGIQII
SEETLHKLIATAQSPLHTDAHVHAPLHGMSFCFSGDLDGMTRAQAIALVQRLGGTVKTAVSTQLTYLVSNDPHGQSRKCQ
NAVRCGVRIISEHVFLALCTPGT
>SEQF2545_AGK84280.1 recombination protein O [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCVASRSWYAQALVLSLSAFGEGHKSVTLFVRLQDEAFILRAALFGGAQSKLRGLVIPYTTGRVWVYSNPRTSMHKIVDF
SVTHSRVALRDSIVRVWCAAICVDIIEASKGTISWTLVTAFLDGISLSSDGACKHALLRFLWRVLIGEGVAPNITSCSRC
ATQYAVSVSGVSRVAYLTQGESFVCAACAAPAEHRFELNAEAWHFLNTVKECTPRHARALVLSQESYCELKQLLFCLITK
MSGKKLKTLEHAHAVL
>SEQF2545_AGK84281.1 tRNA isopentenyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRLETQALVPYPVRFDRSHHDALVVLGATATGKTALAVALAQKYQGEIISADSRQVYRGLDVGTGKDLALYGSVPYHLID
VCDPYEEYNVFRFQQAVYGIVPSILRAHKVPIIVGGTGLYLDAVLRQYALVPVERNQALRASLRGASLSHMRAVYFSLKD
SHAVHNKTDLEDPARLMRAIEIAVFHATHPELLQQARETRPMMRAKVYGIQYPRSMLRARIRARLEQRIRGGLIEEVAAL
HKGGVSWQRLEYFGLEYRFTAQYLQGIIATRDEYVDLLFRAISRFAKRQETWFRRMQRLGVKIHWLVHTENGFVLR
>SEQF2545_AGK84282.1 hypothetical protein TPFB_0637a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPRVCFLSKKKEWGEWLWRVPLSGVDCRYEHHERAVGVAKTRLPGPNAVGNAGTCTVPCSL
>SEQF2545_AGK84283.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGTLRRFPASVLQIALALFLLASGARGLVHVDAGVFNAAVYFLGGLFRGHVAIGVLTLAVSLCCLTAGFFLLVDFLRPEL
SCVSAVLALFVVLWALNMVLVDVVGAFGRGKVLQNVSSALEHLHHTAVDLLVLGALIFVRQHTR
>SEQF2545_AGK84284.1 methyl-accepting chemotaxis protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLPPSGEGLCALDRPSLRCYRARSCELMPEGATMYAGTYSTPPISVLLRELVLSCCWVPLLFLSASAAGFFGDGQFVELL
LSPASVLYLLCLFPLLHYRALCAAFIRGEDEARFSKRVNSYGRTALHASVLLSCFVPFVSILARSPFETGPQMAVYVMLS
AGGCLLFAPALHFLLTRPLERWAAFLPLRESSVCANWTRMLLTIAIALFVATLLLVSAPLLVRTDSQNITPAELLTMAGT
FGLCASAVSCMEFLLCAYLTSREITRLRVLAECIGTGDYTCADVPRETRTSIGLLARSLSSLRDKDRAFFSRFLQLTQSS
SAIAHTAETDIAHLEEAARTTNEEIDHVNENVTAQTATISSSKEIVGTMVEGVGRLNASVEAESETVTRSITLVEQMVEK
IYSIEKIIESNDARVGRLREETNRAGNLTNRSLELTQNISKSSKALLQASLVIRKIASQTTLLAMNAAIEAAHAGQDGRG
FAVVADEIRKLAEESNEQGKIISSVLVQLTEKIEHIAQQAESLSKQFSNLFVLAEEVKQRESTVMHAMEEQSSGGEYIRR
SMEAITGNRRRIRGGISLMLKDGELVLKDMNELAHNTGGITVAMHDMAASTSRILDAVTSVKIIASENKNAMDMLTNQLT
QLRL
>SEQF2545_AGK84285.1 methyl-accepting chemotaxis protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNTEHAVSDFAVLRRAVVMSVAWVPATSLVAYIAGVIDGSMLSALLTSVSFFCALALMLGASLTLYYVLLMSVKKHQNDS
AAAEAAFLRYTWISPLPPAVAAVVYPVCAALEVGFSSSHVLLLSYYLSSVGAALCLIPFFHHPFFYTLQEWAHFIPLRET
RLGYYSLSREISVVLVSGLFSMFCVGFSSLLLPLHGEQELAHVVITHNLPCASLICVLSVIVMIRIGRHLDLANQGILTF
IQNRLSGDASAASMRVVRRNEFGFLTQSLNKMHKSTRFFLIASRGKMARARKIANSFVRNARTSCAAINEIISQAHKAED
KIKHQSRTIFETQKHVQHIVGNIDRFNGHIGEQVDTVTDAASSVEQMVRNIESVTQVLSDNSNVIETLLLEAKLAQDATI
QSADVGREVLHASEALAEAGAVIQHIASQTNLLAMNASIEATYCKESGQGFEVVASEIRRLAEDASKQGKHISAVLRDVK
TEIEKVSESALAVQAQFALIFSITTDIKAQEEVISQSMVEQTKDSVHVLHAIQHITEITRTLQENSGAILDNSKHVEEAM
LALSRITSEIDSSVSSMHKNSEQVKKYASSVTEIGQKNKDSITDLVTELSNMRL
>SEQF2545_AGK84286.1 histidine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRVGSAVSPKVLKGFRDLLPDEEIERALLVEKLTVALRQMGFVPIDTPALEYTEVLLRKSEGDTEKQMFRFVDKGGRDVA
LRFDLTVPLARFVATHYARLYFPFKRYHFAKVWRGEKPQMGRYREFTQCDFDIVGSDSVCADFEILKSIRHMLYMAGAEH
IRIHVAHRGLFDRFLRALSLSDQAEHILRIIDKRAKMAPHVLTAQLESLCDPVRVQKIMTYVSAGEVDGVAPSFEHTLSA
IETLTGGVSEESTRLRKIYELLCAVNIQSSYVFDPSITRGFDYYTGMVCETFLTQLPHIGSVCSGGRYDHLTALYMKDAV
SGVGASIGLDRLYAAFQQLGMSREHVCFVQALIFCQDSALMDVYQKLCSYFAVQVATEVFPDPRKLSQQYAFAEKKGIRW
GIFVEQRNAVVEDCLLVLRDLSTRKDTRLPAHEVRRRMAAEG
>SEQF2545_AGK84287.1 hypothetical protein TPFB_0641a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSASSPLKVLDYLRHHRIEGHCNGKVLLCAMLTKSACLEKVYQSHYTGARGFCCFSESFKRLSRSFTG
>SEQF2545_AGK84288.1 phosphohexose mutase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHSSQLFERARLYLEEETDPFFAQQVRDLVAQNNIAELEERFLQTLSFGTAGLRGVVGGGTNRMNPFMIKKITHAIALYL
LKTFPEKAARGALRAVIAYDSRVHSRLFAHTAAHVFLAHDITAYLFSDPRPTPELSYAVQYLTCDVGIVVTASHNPPQYN
GYKVYWNDGAQIAHPHEKNITEEMNAITSVVNLEEKVPVKRSAPTIIDAEIDEPYCTSIKEKLFRPGLTKETVQSMRIAY
TPLHGTGALHVERILGDMGFSIMTVPEQRLPDGNFPTVSSPNPEDPAALVHACAYADRVHAEVLMATDPDADRFACAVRN
TRGVLQLLTGNQMGALFTDYILLTLQEQNNMPARPAIVRSVVTSPLSDRIARTYGATCVECLTGFKWICGTAEKISQSGV
YSYVYGFEESYGHNFGIQVRDKDGINAAALCAEMGVYWKLRGMSLIDRLHQLFRTHGLFCEKTLNKTYAGVAGVSTMNAI
MNTLRRQPLTQIARKRVMKVRDIYLGVEFSPENPAQTSALSFPQSNVLQYFVQDGSIVSIRPSGTEQKIKCYIIHPLTVS
TSIEEAEQAGNMFITAVEQEMGTYLQ
>SEQF2545_AGK84289.1 DNA-directed DNA polymerase III epsilon subunit [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIYDWVFAVHEHVAFTAFDTETTGLKAEEDRIIEIGAVTFDRKGIIARFSTLIFPDRAIPPDVSKINHITDDMLVNKPRF
CEIVSDFSRFIKGTVLVAHNANFDVEFLNAELSLCKKQPLSHKVVDTYAMAQAVFPGLGRHQYRLQNLALQFGLTVHAAH
RAEDDARVCMELFTTMIAHHAKQNGHCVNHAQSPTIKKLIQEIQASSTDCSQELF
>SEQF2545_AGK84290.1 lysine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSICEKSLHWADKVAHKIIKERADCDQYTCASGITPSGTVHIGNFREIISVDLVVRALRDQGKSVRFVHSWDDYDVFRRI
PDNVPAQDELKQYIRMPITSVPDPFQQEDSYARHHEREIESALPEVGIYPEYVYQSKQYQAGVYAQEIKIALDNRHRIQA
ILNEYRDEQHKISGTYWPVSVFCTACHKDCTTVDAWDSHWCLQYHCECGHGEQVDLRQTSAVKLSWRVDWAMRWSKEHVV
FEPAGKDHHSQGGSFDTARLISDHIYHWPAPVSFRYDFIGLKGLPGKMSSSAGKVVGLRDVLEVYQPEVLRYLFVSTRPN
TEFSISFDLDVLKIYEDYDKSERVAWGIHAAKSEHEFMRHKRIYELSQVRGMPPCISYQVPFRHVCNILQINSGDISAVL
AFFSDIHKDQIERFVRRCQCAWNWIRDAGAPDDFKFTLKEDGVRVPLSAEITEALRLIRDTLVPRTDVLSEKELSAELYA
VARQIPVGSKELFTALYQVLIGKNQGPRLAGFMKVIGTQRLHRMLSVY
>SEQF2545_AGK84291.1 hypothetical protein TPFB_0645 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRAVLTRTQFLFSLYRGSDHTVCQADASTHRMAVVCMRHCHLCGSVGCARGKCVLAWL
>SEQF2545_AGK84292.1 hypothetical protein TPFB_0646 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRMRKVACAFRKLWCRFVVLSISILVSCSVVTRHPLRLGFFTFFLLGSFLVLVSSCTRWMGRELHGQRLFALTYGDAEN
QLHFPDAGYAQSQSNIQLCMKDGIFYVAHAATGKVMRMTSFGDVLAVIFNPEKNAMTPQFSEGLQSAAITTRRAVPYPLH
TPTFLAVDSQNTLYVVDAVLPEHVQHDPEENLALVNTILLFDEEGRFMHAIGQQGIGGTPFPAIEGVYVNSADELVVVCR
SVDAMRVYWFNAQRVPIHQRALPFSPLPTSFAAQEKGYAFVERVLPDVSERRLIAKVDYYTAVHDPATGANSSVRYAKSS
VYFISLETGVYEWKVDLPAHEVSGTENQERGPYKKAFSLLGVSAQQGILCVSPDRFGYAALLLDLRSFTIRQRSIHMRSD
TLVYNVFHFSPTGILSSVLATDTEAVVMWWRFDRILSRIK
>SEQF2545_AGK84293.1 serine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLDYRFIRENVDAVKENVKVRNVHADVDAIVHLYDQRVKLLAELQELQRARNENAQTMKSSLDALARSACVETGRALKDR
IAHSERLLVQISDQLLSATQALPNMTHMCTPHGRSDSDNLEIKRCGVPPCFSFSPRDHVELARLLDIVDFEAGKKVSGIK
FYYLKREGVLLEQALIMFGLQFLQERGFVPFLTPDIAREGMVCGLGFNPRGSGSNIYRIEGEHRCLVATAEITLGAYHAG
EVLEERSLPRLYAGLSHCFRKEAGAAGQFSRGLYRVHQFTKLEMFAYCTPSDSECLHERLRSLEEEIFTALEIPFRVVEV
CAGDLGAPAYRKWDLEAWMPGRQGGSWGEVTSASNCTDYQARRLNVRYKDAEGKKHYVHMLNGTALAISRVLIALLENGQ
DAEGRVRIPQALVPFCGFEYLYPRVL
>SEQF2545_AGK84294.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYLSCGVIPSLHVYLSGHRGKGKSMKGLLCVYYGALCSIVFAQTGVQLYEAGRKAHVQEDWHAAIEFYQEALKKNASYNL
AYRGLAECFYALGEYDQALHHVRKAQKLMAQDLSLEKLCAFSLVGQGELDQARSLFEEILARYPNDVDARFGLAEIEVSK
GRLSSARLLYQAALERQAENRKALLSLALISYEAGHYPRALTYVERALQYHGDNAQVHFFAAYLATLRAHYEDAERYLER
ALHIKSAYPRARALLSAVLYARGAYERAVAQCDQRIRADRTQVDAWYVKTLSLLKLGKHTEALATAKVGLTVDPRDDLMR
ILLEEIAIVHLEYEDEYRMQLARFHTQKADGFARRNMSRQALDEYRRALKVYPYDGAAREAYARLLLRFGYPERSLEQLK
FLQSIGKSSARINDAVEAYEKTHARSIKNRWRVDALYLDKAHLSISLFYHPDPANALHPEAERFFLTQVQDSFAYNRRLK
VTGYSARSHSYREAFRTAREAGDDYFALITMQEHGQDLRVRLELYVASTGSRAHTFDAYRSGNDRYQSVLRRIMQMLNDR
LPIMGTVVRRHQSEAVIDLGTQDAELQGKSLEVVKRRAVSVLKEGVGLAYRREDVLGHFTVTKVSEDMSEGVLRRVGYYD
HISVGDAVICEPRLPDSSATTSDTFVHDGAMGMLLALLRSIR
>SEQF2545_AGK84295.1 putative hemolysin [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGVIDWLRRRHAVTHIFQQPLNEEKQDMIRGIVDLSDTSVREVMIPRIDVDFLELSMSGETLVEKVTESGHSRFPVYEQT
IDNVVGVLYVKDLIKLFGRPQEVRLERLLRKPFFVPESKRIDSLLREFKRRHVHIAIAVDEYGGVSGIACMEDIIEEIVG
DIQDEFDHEREDIEPLGQGVWLCDARVDLEDLSECLHTVFPSQEFGTLGGFVFNLFGKIPVKYEKVSWGAFDFIIQDMEA
HKINTIKIVSVLRGDSEPACVSERP
>SEQF2545_AGK84296.1 hypothetical protein TPFB_0650 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSEVNKVSVSCEGFCPPPWIGQVAPFVCAVLDSQAISHWDLSIVCCTDAFIRRLNYDYRGIDSPTDVLSFENDGEYCDDA
GTRFFLAGDIIISLESVRENSERFHVAAHEEFKRVLIHGILHLSGMDHQDNSPGQEMLRLQERILAQHCRVLSSGIPWES
>SEQF2545_AGK84297.1 membrane-associated HD superfamily hydrolase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRYLGMFCQGSRLGYARRPCVLAGQITAGVLRSLAREVRMRKKGPPRLTQLWHTLCHVLRRRRARALNLALSFVVLSIA
TAVSISEQHDPARLNLADFAVGRVAERNVVSPVFLSLTDELATQRQYARRKKEIPAVFERRLDLEQAEVRAYQAFCHALQ
KARVGMALDTSSDGGGGAADYEEERSLHAAHDRASAHVHLLQQKFVHFSRQTLRSLLQLDDDTFESLLRVGTQVLARIFA
QGVVQLSDHALKDFNPHTITISEERPFHAPSDMSAPVASQASAGDLPSASVPLSPDASADEAENAAGDVFSRTQAIETLI
RSDQLAARVHALASDFGLTSQAALLFSSLGPFLRPNIVFDPIQSERHVRNALARLRPVTLSIHPNEIIVRRGFIVSATDY
ARLQALAHSKLSVDRSLLVSSLLLLAFLYLLAFFLFSKRMAHPPLKLRVELLILYTSVAGYLCTLFLSKIAALPAPLDSI
PFQPTALCIMLVTALVSHRSAVTSSFLIAFAVLIASQFHTEPTLFALLSGVSASACMRVMSSRLDIVKSSCVLAVAQPFL
AATLMFAFPHAYTDAIFLLTGVAISGFLNGILVLGLLPILEALTNAPTVFRLMELSDLNVPIMKKMLLTVSGTYNHTMMV
ATLAENACRSIGAHSLLARVGAYYHDIGKMENGEYFVENQTGDSKHLDLNPRLSATVIRSHVKLGVEKAHQLRLPQEVID
IIAEHHGNSLITYFYEKARELDPNVDREDFTYPGVPPRTKESAVVMLADVVEASCRTLNKPTIPRLGKFIDKVVQQKIET
HQLDNSDLTFRDVQVVKECFVRILAGYYHSRIEYPHQRDSDQQQLVSVAQGSYKE
>SEQF2545_AGK84298.1 spermidine/putrescine ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKGCAVTIDQVSKAYGHCLAVDRATVHIRQGEFFSILGPSGCGKTTLLRIIAGFEQPDSGDLTFDHVSVLGVGANKRRSN
TVFQSYALFPHLSVYENIAFPLRLKRLSKNLIRERVHEYLHLVQLDEHLHKKPHQLSGGQQQRVAIARALVCEPGVLLLD
EPLSALDAKLRSNLLIELDTLHDQTGITFVFITHDQSEALSVSDRIAVMNKGKILQIGTPYEIYEQPATDFVAKFIGETN
SFLSTVVSCTAIENEEFMLSLQVPELDRTLTVTADNPIDPGRRVCFTVRPEKIHISLEEPGTTSAPLNVFRGFVEEPVYA
GFQSKFFVQLESGAIIQVFQQHQKYLDTGPEIAWKDTVYVSWSAHDGYVVEDIES
>SEQF2545_AGK84299.1 spermidine/putrescine ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSSRLRVARRHTVGSLGFWCTLPLSAWLTVFFLCPLTVVAVYSFLQKGLYGGVVWKFSIRAYAQVLTSGYGALLARTLLI
STGVTCLCVLLALPAGYALSRSRRQTFFLFLIIVPFWTNSLIRINAWITILGNQGFLNEALKSLGFITRSLPLLYHNGAV
IVVLTYMFLPYAIFPIFAAIDRFDFSLLESACDLGSTPTGAIIRVLLPNIKTGIATAVFFTFIPVFGSYTVPLLVGGKDS
YLIGNAIVDQVRIVGNWPLASAFAMLVTLAGGVGVLWILAESGACNTTPPPCGGRRSYA
>SEQF2545_AGK84300.1 spermidine/putrescine ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPNCRLIHTRARTPLRCSFSAVLLAAVVSFLFLPLAVIALFSFNKDKSLIWTGFSLRWYTELFFYSEKLWSSFLNSVLIA
SVSALVATIVGTAAAIAIRWYRFSGRLYAQVMSLLPMLLPEVITGMAMLVFFSLVRLPLGRASIITAHITFCLPFVLLLI
LTRIDTFDLSLIEAAQDLGANEWQALGKIVIPAIMPGILSGFLLSVTLSLEDFVITFFVAGPGSTTLPLYVFSMIRYGVS
PIINALSLIMMAGIVGVAYLLRNSLKTIVHSK
>SEQF2545_AGK84301.1 spermidine/putrescine ABC superfamily ATP binding cassette transporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRFCVSSSRILSLLFLSLWMGSCLQTRQDVLYLYNWTYYTPTSLIKKFEQQYNVQVVYDDYASNEDMFAKLSIGASGYD
LVVPSGDFVSIMKRKHLLEKIDLSKIPNVQFIKESVRARIAYDPKMEYSVPYYLGAAGIAVNKKAVPSYARTWSIFSRKD
LAYRMSMMDDMREVMGAALASLGYNVNTKNEQELAQAAILVTDHWKPNLVKFDSDGYAKSFASGDFVVAHGFAEAFFAET
PEAMHEHIDFFIPQDVASPVYVDSFCIPKGARNRDLAHAFINFFLEPAHYAEFLDTFGFPSTIHREAAAYQKKTPYYSEH
DLERGTLKTDVGAAIEHYNAHWNAVRFR
>SEQF2545_AGK84302.1 carbon storage regulator [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLILSRKTNQKIFIGDSIELTIIEIRGDQVKVGVEAPRSVKIFRQEVYEEIQRENRAASDSPWSPNSLPQLPV
>SEQF2545_AGK84303.1 flagellar assembly protein FliW [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEIQTKTLGTQTVEAHQIITLERGLYGFEKYHRFALFDAVQVPFIHMQSLDDPALSFIAIDPFLFRPDYELDIDDVLLQP
LDISSPTDVLVFALVTIPPDGSAVTANLQGPLIVNKKNRKAMQVAMGGDRWRTKHDIVAEMAERRAQEQC
>SEQF2545_AGK84304.1 flagellar hook-associated protein FlgL [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGVKRISSHMQGTDSAFFLREQESRLRKVNNQLATQRRIQQLRDDPLAAGHSVRYKSSLARLDRFERNTKTLRDQYQIAE
GFMTSALNVVQRLREMAVAGANGTYTPDDLKKMASEADELLQELVHNANAVSADGVRVFSGTKVFTEPFETVMGNVEGLG
SEVITQVRYHGSLDPKNVEIDEHSYVGTHQAGSRVFWAERQILLSSVDARAYVLQQDARVTVDGVSIPLVAGDNVYAIIS
KINDSGAAVRAYLDPVTNGLNMETSDARQLWLQDEDEANVFASLGLITEGQRPPYNVSAGARVSGGSIFDMAIAVRNALL
AGDQESLGGKILGSADGAVDNLSLRLAETGARYARAQATLARFNSHIPNVVAAESRESDIDLTQAITDLKMFEYTHQATL
STVGSLYKHTLLDYLR
>SEQF2545_AGK84305.1 flagellar hook-associated protein FlgK [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSTFASIELGKRALYAHKQSVQTAGHNVSNSSTPGYSRQRVNLDSFEPLYRPDLSRAQLPGQIGQGVTIGSIARLRDQLL
DSRIVSQTDEQGYWSTRDAYVRLLEQVYNEPEDIAVRTRLDQFWDGWQELSVYPEARAARQVVLTRAQTLTDAIHHQYRG
LVGIRDMLNADIEATVEQVNDLLAKIAQLNEQIVKSKAMGDNPNDLLDRRDTLVESLAHRIEVRVDVRDEDESYVIHSAG
LEVVQGKSYKTLGLVSGTTPEGYVSVVWKDSGDRAHFSGGKLAALIELRDTDVRDELRKLDTMAMNFVDLVNNVHRNAMG
LNGKTGLDFFKEQYFINNVDGNFDRDGDGQYDSSYIFRISGAHALDAREQVGLTGVITLSAADGTVEVPYAATDMVADVV
ARINQANAEVTAYLDQNHKLVLKATTAHNSDNPDFVIRHVEDSGRFLAGYAGLLAASGAEGAFDWQRADAIAALDQAGAQ
HAVSPIAHPAGWMELNPAVLSDVYSVAAGYPSAEGLPHAGDNRAALAIASLRNSPVMIGNRHTFDEFFAEVTTAIGLKGE
QAERSMQMHAAILKELTDMRDATSGVNIDEELADIIKFQHGYNASARFIAAVNEMLDTVINRMGV
>SEQF2545_AGK84306.1 hypothetical protein TPFB_0661 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDRERALHRAGQVEAILVAQIELVGQVIQVQRSVYESLRTRAWEHVESFVSRAQALSREFLHLDKRCFLLLQEVRPYGDA
PVDFDSFFAYLRRADVNVHDAVVALYRTLRSKVASSKNEHDAIQHYLTHARGLAHALVSALTCEQQGSSYTKDGCPVRCA
PGSLVFDRVL
>SEQF2545_AGK84307.1 fructose-bisphosphate aldolase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTSYKALGLVNTKDLFAKAVKGGYAIPAYNFNNLEQLQAIIQACVETRSPVILQVSSGARKYANATLLRNMARGAVEYAH
ELGVDIPIVLHLDHGDSLELCIDCIESGFSSVMIDGSALPYDENVALSRKVCEYAHARADYVTVEGELGVLAGVEDDVVA
EKSHYTMPDEVEDFVKKTGVDSLAISIGTSHGRAKFTPEQCTRNADGVLIPPPLRFDILAEIEKRIPGFPIVLHGASSVP
VEYVREVERYGGNLPDSVGIPEEQLRKAAKSAVCKVNIDSDGRLAMTAAIRRVLTTKVDEFDPRKYLGPARDELKKLYMH
KNKEVLGSAGRA
>SEQF2545_AGK84308.1 putative flagellar filament outer layer protein FlaA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKQGCFMVAGFALTCAFLVSPLAAQRSKVNYQAYFIDDFDGASEDQGLAWRAAGSKFITKGFPILKYFEGMPQAVRMAGS
WQGKDKEARFIGVECKFNRQGNNWLDLIPTKGGSDYEIPLRGVVSGFDVWVWGAGYQYSLEALVRDCTGRVHTLPIGNLD
FQGWKNLSVSVPTHIPQTSRYLGSAQHLSFVGFRIRTSPSERVDDFYVFFDQFKALANMHIDFYDGHELRNAQFKEEGES
GK
>SEQF2545_AGK84309.1 flagellar filament outer layer protein FlaA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKIAVVSVGVLVFSAHAQEAAGSRDVADPSRIGVYAAAQRLKEVSVDKFENEGTWVVSMSSDEGTIKGRLFEGGPARKR
PIPEEGDMKIPDSKVFGAKVSFYRRGYNSFEVSSVKPLPVEGVAKTVSVWVAGRGYPHSLSLLLEDFWGQRFELHMGQLD
FSGWKLMSVAIPPQHVDGKTGIVQKSRRFPNQSGLNIVGFRVDCDPLEAYGNYYVYFDDLRVVTDLYDVESREPDDMSDA
W
>SEQF2545_AGK84310.1 hypothetical protein TPFB_0665 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTINTCRETGLHRALKDYFSPRGSRQEVELRGSICDVVHPDGTIVEVQTSGLGRLEAKLKKLLPYHQVMVVYPVSRRLYI
RMLNEDGSERHYRKSPKEGSFFQIYREIGRLHDLLDHEHLSLHIVYIHSEVIKVDDRKGRSRYKKPRIVDRKLLEVQSSE
EFRNKGSLAQPLLSKLPEIFCCDDLAQTGTGVHCRYALRFLRRNGMATPHSKRGRTKLYRKEPPGDNRSPPPWQEPHGEG
LAEKLSPGSAR
>SEQF2545_AGK84311.1 hypothetical protein TPFB_0666 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQKGSGASSVMTLYEYYLIFPDGECREISGPPCERSLLDMDGHPLRVPLSSNRVIAYRVAGKRTVAGGRGVVGIWYTLEQ
LDALELLEYVSGPLGQR
>SEQF2545_AGK84312.1 bifunctional phosphoribulokinase/uridine kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGTFVVSLPGGRREKFSECVPARVLFERFFGTESSVYGLMCNGTPVLPCQVIGADAVVEPVREDTVLGAALYRRTARLLF
ATAFHSVYPHVRLFAGYRVQGGYCYRTEGACADDLDVSLVVRRMKALVAQDAPIHMQYMTRQEALNLFTQWNFPYSHHYI
LGSYRTVFLTQVLDGFSALFFQPLMASVGRLTVFEVRMCAEGCLLRFPEGGQRHIISQHNASPQFVVMYRRHRQQEEQTK
ICSVGQLNACIQSGDVATCVDMAEAAHNRQIECCATEIARRDSVRVVSIAGPSGSGKTTIAKKLSVQLQVLGYDPHVISL
DDYYVGIERTPCDAEGNPDFECIEALDLPLINKLFLDLLQGKRVALPSYNFKTGKREYRGREVQFGERSLLIIEGIHGLN
DRLISLMNRRVVFRLYVSVFMHLCLDEQHRVSASDGRLLRRVVRDAQFRGISVEKTLEMWQRVRAGEERYIFPFQHRADM
MFNSALVYEFAVLKRRAQEVLSTVSSACTTYREVRNLRALLEQFCSLSDVHVPGQSILREFIGQSDFCYCL
>SEQF2545_AGK84313.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSSVLSTLSALLSVYALLCTARVFLSWVPHLSHSPLGEFLSAICEPYLSWFRRFSFMRVGTVDYSPMIAIGVLTILSNTV
GTIFLVGSVSVLKLLLQMLMLLLWSLCKFVLEFLLILFAVRFVSDRMNVNVHTLFFVMMDRILNPVRVALTAPFKFLDLS
YRASLLLCVLVILCARVLGGFFVNVVVRYFLTGTLHVAVM
>SEQF2545_AGK84314.1 DNA-directed DNA polymerase III alpha subunit [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARMSFVHLHVHSNYSLLDGASSLQRLVRTAKSLGQEALALTDHGNMFGALHFQKVCSAEGIKAIIGCELYVAPESRFDR
SEHTIGRRYYHLIVLAKNETGYRNLMVLSSKAYIEGMYYKPRVDDELLAQHAEGLICLSSCLAGQLPYLLLQGRKREAEE
HARKYRALFGVDNYFIEVQDHGLDEEKKVAPLLIELACRLGIPLVVTNDVHYAEQEDSVAQDILLCIGTKKNRSDPNRLK
FKTDEFYLKSSEKMAQLFPHYPEMVLNTVRIAQRCNVRIPQPGPLLPLYQIPHEFSSKEHYIRHLVHRGLYDRYAVVSEE
IKARADYELDVIVRMDFVGYFLIVWDFITWAKEHDIPVGPGRGSGASSIVAYALKITDIDPLRYKLLFERFMNPERISMP
DFDIDFCFERRQEVIEYVRARYGNDNVGQIITFGTLKPKAAIRDVGRVLDIPLSEVLMITKLMPDDPKLTFKKAYESEQL
AQMKQEPRYAELFQIAEKLEDTNRNTSLHAAGIVIGKTALTDYVPLYKDSKTGKISTQFGMDLIEDCGLVKMDFLGLKTL
TLIQRTQNLVRRKGGKYTTFSISDISDQDPTTFSMLAEGKSAAVFQFESRGMQGILKRAKPSKMEDLIALNALYRPGPMA
FIDQYIESKRDPGKIKYPDPCLEDILSETYGVIVYQEQVMQVAQRIAGFSLGEADILRRAMGKKKLAVMQEKKKEFAERA
EKQGFDKKHAENIFEILIPFAGYGFNKSHATAYSVVAYQTAFLKANFPAEFMAANLSNEINSAEKLPLYMAEAEKMGLSI
QKPDVNASEPYFSVCEGCIVYGLLGIKGLGEQVAFDVFDERIRNGPYTSFVEVLDRVPATSLNKKNAEIMIKAGCFDRFG
VTRASLTAHLDDAMKYVARKKAVTSSRQASLFDETDLGECSEYTFPVMEEWSQRERLRIEKELMGYYISGHPLDEYRSVI
GEKATLDLGHIENARSENKYLIVGVLNAIHPYTTKSGKNMAFGSFEDLHGSVDIVVFPVLWEEHRAQFLPETIMGLVGTV
DFSKETPAFLVDSVIDLEQLRFAQVKTILAGSEHRRVSSGEKTPLQKRGVSQEVHIEVSSHVRAHAQFKSLYEILSAHTG
GSGEVFLHMHVDDRTYVVYVPSCKVSATEVFAQQLKGNESFVQILKECVQ
>SEQF2545_AGK84315.1 hypothetical protein TPFB_0669a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRAIITKNGAPDKQSELQHSILGLLTRYIFLSTLAGFLLAAYHGIIAHPDRATAF
>SEQF2545_AGK84316.1 D-alanine--D-alanine ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVHVTLLYGGRSAEHDVSVRSARFVARTLCLQHTVMLIGITRRGVWYAQPACALEQLCTGTVALSIQEDEKRRVCLVPGG
GTAGAFVIAGMPCVTDVVFPVLHGSYGEDGTVQGLLEMLQVPYVGCGVCASALAMDKVKAKMLWQAAGLPVLPFVFFRKD
AWRMHMQEFVAQLETRLGYPLFVKPAQAGSSVGASPVQTRAPLIPAIEAAFQWDEVVLVERYVRAREIECALSGNGPYTV
HGAGEVIAQGAFYDYEEKYADASVARVLVTAPLETAQYEQITTLALRAYEALGLTGLARVDFFLLETGEVYVNEVNTMPG
FTSISLFPQICQAAGVAPQDLMAQLLSCARERFAARAALSTDLHAHVCAPSVTAAHDPDAQGDDWDQRDSNPLPTA
>SEQF2545_AGK84317.1 ethanolaminephosphotransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKAYSYAVEDRSLLTPFLYRFCVDPLLRVVPYRVPANLITLCANACMLLAFTHAYCGSVGGTYAYWFLVPVLCIVYLVGD
CLDGRQARRTGTGSPLGEYFDHCLDTSVVGLLAGIFVLAFRIREPFLLTCIFFVPAFVQISTLWEKLHRGVMVFARIGSN
EMVVLTTLGAYAGSFETLRALFLTPLFFSCTPAQVCVSVLSTGVCIFSCAVFWRMRVFSCALFLHLSLFFFLCVFSSTYF
PTQIGYITALCTLYHMRYAERLLRVIVQGEGTARVEVLVPLLCGVLFLFPQTSFWVQRAQCSILALEVGVHFVRFVYAHR
CYWHWLNPLPTQE
>SEQF2545_AGK84318.1 glycine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFKGGRDLCEVAAGADSMLDRGEGERRVTMEKIVGLCKRRGFVFPSSEIYGGQGGVWDYGPMGIALKNNIAHAWWQDMTR
LHDHIVGLDAAILMHPNVWRTSGHVDHFSDPLVDCTVCKSRFRADQVAVPSAGGPCPQCGGALTGVRNFNLMFSTHMGPT
DERASLLYLRPETAQGIYVNYKNVLQTTRLKVPFGIAQIGKAFRNEIVTKNFIFRTCEFEQMEMQFFVRPAEDTHWFEYW
CAQRWAFYQKYGVRMNHMRWRTHAAHELAHYARAACDIEYAFPMGFRELEGVHNRGDFDLTRHAQHSGKDLCYVDPDPNL
DAAARRYVPCVVETSAGLTRCVLMFLCDAYTEEYVQAPNVAFSETTQTADQEGAARTGEMRIVLRLHPALSPTTVAFLPL
VKKDGLVDLARAVRDELREDFACDFDAAGAIGKRYRRQDEVGTPFCVTVDYQSKEDDTVTVRLRDSMAQRRVSRAFLAEF
LRTEIKHYRRP
>SEQF2545_AGK84319.1 glutamate--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEVRVRYAPSPTGLQHIGGIRTALFNFLFARAHAGVFVLRVEDTDRSRCTAAFEQNLYDTLRWLGVSWDEGGGCPETAVK
QGARGDGRSVAHAGGAYGPYTQSARTDLYRAQVARLVETGQAYYCFCDASRLERVRKIRTLNRMPPGYDRHCRELLPEEV
RECLASGVPHVIRFKVPLEGSTHFRDALLGDIEWQNEEINPDPILLKSDGFPTYHLANVVDDHAMRITHVLRAQEWVPST
PLHLLLYRAFGWQPPLFCHLPMVMGADGHKLSKRHGATSCDEFRNAGYLPEALLNYVAMLGCSYGEGQDLFTREQLCAHF
SLSRLNKSPAVFDYKKLAWFNGQYIRAKSDEQLCALVWPFIANAGVCGHIPADVEAGAVRTRRFADEAPCAPTEAQRSML
MRVIPLIKERLRFLTDAPELVRCFFQEPSLPEQGVFVPKRLDVAQVRAVLVRARGLVHEIVSASEPDVEVLLRAEAEKFG
IKLGDFLMPIRVALTGATVSAPLVGTIRILGASRSCARIEHVIRERFSDDSQGVGGG
>SEQF2545_AGK84320.1 Smr domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHRQVFYERMRPLMAGKRRKDILPLEEALRAQSAFARTLRTWEGARRAAVRSATVRARRRGALPSSQAAAAPRVSLMEVA
LARYGLFDKDAAGACAEYARQRRTFSIHSRRGRRKLRTAVPEARLDLHGMTCSEARSALDSFFAQARERLLQKVEIVHGK
GHHSKGGSVLAPSVKRYVQAHPHAGELFHPAERRGGKGTTWVLLKRSVPLH
>SEQF2545_AGK84321.1 hypothetical protein TPFB_0675 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNTTGRPVFPLLRRTVLKRCSLCATRCAIVFLCVLLILPFLSCCTSLSRGALPSLISHKERMFWEIRGPQGSVYILGTIS
VGSEKLLHFQDKILDVFDSASRLCAELGSEDIKNFASVLQRRMLHGMLEQENAAPTLSSLSREELEMLRSTLGDDMHTLS
RFEPWVMRVALYQALIAHTKLDSGKNIEAFLYQRAGNRKILGLDSIQKHLNMLSFGNREEQITLLRALIALGKSPADFKG
RLGALVRSYLSNDKTALGRVSTELDALVTKDAAGGLHRRYVAEIAASRRAAWAEEFYRLSLQHGITFVFASAGHFCGPES
VFDIMRKRRLLQ
>SEQF2545_AGK84322.1 hypothetical protein TPFB_0676 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRCSHNWDDPPPLFGAVSYGMQEGAGRGVRREARDTPCRGTAEGLATSQPEDGETRAALQRIDHLDTQLLQLERDLAHYL
EMAELPDPFSEN
>SEQF2545_AGK84323.1 hypothetical protein TPFB_0677 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQYSGPMQEEVSERTCLVSDPSLSSVAGAGSGVVQAYVARQLARQVHACVDCGMRGIRRAVRRFAADVIAREAPELTAAK
REALLDAWVPSPSSEHVAVGSQPAQACGGAPLPADVQYSMVLHFVWYGLGVLSEQERVQLEQAVPHWPQVYWSCFSPQLK
RLIKACLTGLLDVEAFCAAVRTLLGIAGMDTAADASIHPHEK
>SEQF2545_AGK84324.1 hypothetical protein TPFB_0678 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEAYQAEIIRRFGRVRRARGFYLYTERGVRITDLFLDGGASILGRNASRARLDFKRYLSRGLWGPLPTCASAQLQQALRT
CFPAHEVRYYAHAERAQEVCARFLNLACGAAPCEVPVWRPCAPCVPQTDVFLVVPPFPSPAPFVALRAHCAARAPAGDVL
FAPIAQAIARAFWDLARVGSLSQPARAMPHALLDSSHTTQEDAVPALPHTKKRRRGLNRVRRAQKCARQERDRAQLITLM
STWWRTEGPYLFPTVSEERYEALFARALDAHILLSPLYTEPSVLPTLEHYTQLCTFFLQEQEKEHHE
>SEQF2545_AGK84325.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNEFLSLLSRAQTILLMLRLAVTAVAVFLAIVAWTKTRTQETVCFIAGVLCMYLAQLFAFLRAAGFSITRYTPVPGVSLV
GFTLELLPLACFIASLIFTIKRHSI
>SEQF2545_AGK84326.1 O-sialoglycoprotein endopeptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNVLGIETSCDETAVAIVKDGTHVCSNVVATQIPFHAPYRGIVPELASRKHIEWILPTVKEALARAQLTLADIDGIAVTH
APGLTGSLLVGLTFAKTLAWSMHLPFIAVNHLHAHFCAAHVEHDLAYPYVGLLASGGHALVCVVHDFDQVEALGATIDDA
PGEAFDKVAAFYGFGYPGGKVIETLAAQGDARAARFPLPHFHGKGHRYDVSYSGLKTAVIHQLDHFWNKEYERTAQNIAA
AFQACAINILLRPLARALQDTGLPTAVVCGGVAANSLLRKSVADWKHARCVFPSREYCTDNAVMVAALGYRYLIRGDRSF
YGVTERSRIAHFSKRGGDRLAAQRSAASQPLF
>SEQF2545_AGK84327.1 alanine racemase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MACNQALIHLANLRHNLGEIMSRTRARVCLPVKADAYGHGACDVAQAALSCGVHSFAVACVQEASQLRAAGVRAPILCLS
TPTAEEISSLIEHRVHTVISERAHIALIARALRQSADTGATCGVHVKIDTGMGRIGCAPDEACALVQMVCATPGLHLEGV
CTHFSVADSVRAEDLQYTEMQRAHFMHCVQYIRKSGISIPLVHAANSAALLCHPRAHFDMVRPGLLAYGYAPESVHPAVR
SVFLPVMELVTQVRAIKKIPAGAYVSYQRLWRAHTETHVGILPIGYADGVMRALSPGLQVCIGGKWYPVVGAICMDQCVV
DLGTPLRVTVGDRVTLFGPQDAGGPGQGADVLASHAGTIPYELLCAIGKRVERVYIR
>SEQF2545_AGK84328.1 23S rRNA methyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNVYKRADFWAKKAAAAGYRARSVYKLAALDKKYSLLSRASRVLDLGAAPGSWTQYVLGTAAACTAVCAVDVQPIASDIQ
DARLQRVQGDLCAADTRARVACNAPFDLILSDAAPRTTGNRTVDTSASACLAAGVCAYVNFLSSDGGLVFKVFQGSEHLA
ILTHLRAHFGAVCSFKPPASRPRSCELYVVARFFRGTCGK
>SEQF2545_AGK84329.1 octaprenyl-diphosphate synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLAQKANTPYNGTMKRALAQRLRNIERALADALPAQPTRSWMGTRLRVLASEDTRVLRTVCNACVSCGGKRWRPLLLILS
AELAHACVQCTHRKLQGHKRKKISEREWYTLSAVVELIHTASLLHDDIEDHSSTRRGKPCAYLRYGTDCVLNAASWLYFH
AHALIDTLSIEPALKAALFSATISATRALHMGQALDIAWHRSPELIPSRAQYLRMVALKTGALIALSGELGFLCAGYSAR
EARSFGAQVMPIGIGFQILDDVQGIDGGVSGKAHADDIVEGKKSFPVILHVHTHPQDAPTFARLFAAARAEGLHSPAVKQ
AQRILYSSEALTHARAYGLRMIERTLTRVHAHFPCNPACQLWCTAVQYGVRAHLHAH
>SEQF2545_AGK84330.1 hypothetical protein TPFB_0683a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARFLSNFFARVASFSSLLPGDLSCRASSPFLSHGVTFCDHLQYMRRGKVSARAGARVPHTALQYTTAGMQDCKENVRAP
V
>SEQF2545_AGK84331.1 galactose ABC superfamily ATP binding cassette transporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKENSCTACSRRLALFVGAAVLVVGCSSKTDVTLNRDKPLVFFNRQPSDPLTGKVDMAAMNWNDKTYYVGFDAKFGGSIQ
GKMILDFLASSESSVDRNGDGIIGYVLCIGDVGHNDSKVRTEGIRRALGTWTGSSDPGQAKEGQAVVGGKSYKVVELEGK
AMTGTDGSTWNTNSATESMGSWVAKFADKIDLVISNNDGMAMGCLQASNYPRGLPIFGYDANADAVESVGKGELTGTVSQ
NVDAQAVAVLQIIRNLLDGSSGEDVVANGISRPDAHGNKISAPVQYWEDAKAIMADNSEVTSANWKEYTRGARDAGVRQV
SAPTKKVLLTVHNASNDFLASAYLPALKHYAPLLNVDLTVVQGDGQNELSCLDKFTNLDMFDAFAVNMVKTNSGADYTDK
LKY
>SEQF2545_AGK84332.1 galactose ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCDVLTIRDLSKSFARNRVLNGVNFRMGKGAVVGLMGENGAGKSTLMKCLFGMYAKDTGQILVDGSPVDFQSPKEALENG
VAMVHQELNQCLDRTVMDNLFLGRYPARFGIVDEKRMFDDSLTLFASLKMDVNPRAVMRSMSVSQRQMVEIAKAMSYNAR
IIVLDEPTSSLTEREIVRLFAIIRDLSKKGVAFIYISHKMDEIFQICSEVIVLRDGVLTLSQSIGEVEMSDLITAMVGRT
LDKRFPDADNTVGDDYLEIRGLSTRYAPQLRDISLSVKRGEIFGLYGLVGAGRSELLEAIFGLRTIADGEISLAGKKIRL
KSSRDAMKLNFAFVPEERKLNGMFAKGSIEYNTTIANLPAYKRYGLLSKKKLQEAAEREIKAMRVKCVSPSELISALSGG
NQQKVIIGKWLERDPDVLLLDEPTRGIDVGAKYEIYQLIIRMAREGKTIIVVSSEMPEILGITNRIAVMSNYRLAGIVDT
KSTDQEALLRLSARYL
>SEQF2545_AGK84333.1 galactose ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRDRTQCVAVPTQAFNEILDQDGQLTAYAQRLEQLRERGSHRVALLRGELARIRQDQVLGMPEKRVQVAAHRLKISEAQA
VARQCKTEETQLVRKAVARVRGLFRDFDCSVRDAMREQRLLLKQVATVQHTSASSDQREHCLAQLRQCKEARHHAYRSLV
EKSAALRNGKMTFIERVVRALREYSFNFDATQFFLANGLYIAIAVFFIACIVVAPFSGNGNLLTIPNILTILEQSSVRMF
YAVGVAGIILLAGTDLSIGRMVAMGSVVTGIILHPGQNIVTFFGLGPWDFTPVPMAVRVVMSLAVSVALCVSFSLFAGFF
SARLKIHPFISTLATQLIIYGVLFFGTSGTPVGSIDPYIKDLFGGRWILGTMQGTLVTFPKLIIPATIAVAIAWFIWNKT
ILGKNMYAVGGNAEAANVSGISVFGVTMSVFAMAAVFYGFGAFFETFKANASAGTGQGYELDAIASCVVGGISFNGGIGK
LEGAVVGVIIFTGLTYCLTFLGIDTNLQFVFKGLIIIAAVALDSVKYLKRR
>SEQF2545_AGK84334.1 DNA helicase RecG [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLIGEIKEPVSVLKGTGKVVLAQLERLNISTIGDILSYWPRLWEDRTQEQMFSQWTLAHRLQVRVSVTAHCWFGFGKSKT
LKLVVQDGQGCVAELLCFRRNFLHFMFPVGSEAVVYGSFYEKDGLLESSSFDIEKIDCIEKKILPVYPLTKGLKQMKLRM
LICAAMDQWIGTVDSELPKPILEKYHLLTKRDVLLSMHTPRTLDDVAKGKHSLIFEEFFSLQMTIGMRSLQKRGRLPLTQ
GESDQQSAIPSVVSELSLLQKKLHRCLPFELTVDQKRVITEITQDLEREEPMARLIQGDVGSGKTLVAFFSCLKIIEQGG
QVALLAPTELLARQHADTAARLLAPIGIRLAFLTGNVKSEGRAYLLEALVAGEINLVVGTHALFSKSVRYHDLRLVIIDE
QHRFGVLQRSALIQKGREGNPQGKTPHIIMMSATPIPRTLALSVFGDLDISIIKSMPGGRKPVITYIARKTKAEKVYEFV
GNEIEKGRQAYFIYPRIHDIGLTDLKSVQCMYMYLKNYFARYAVAMIHSKMTEEEQQRIMKYFSEGTVHILVATSVVEVG
VDVPNANCIVIEHAERFGLSALHQLRGRVGRGDVQSYCFLMHGDEMTECAKRRLKIMGSTADGFVIAEEDLKLRGPGDVG
DTKNFEQSGYSGFRVADPVRDYPILQVAREAAFELLRKEKGSSEAR
>SEQF2545_AGK84335.1 muramoyltetrapeptide carboxypeptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQDEGVDMKKLLLRSSDEVRVIAPSCSMRKIDSSVIERAQERFRCLGLNVAFGDHVYDEDFLGSASVDKRVADLHAAFAD
KKVKLILTAIGGFNSNQLLQHIDYALLKKNPKLLCGFSDVTALLNAIHAKTGMPVFYGPHFSTFGMEKGIEFTIECFKNT
FFYGRCDILASETWSDDMWFKDQEHRQFITNPGYEIIHRGDMVGMGVGGNISTFNLLAGTEYEPSLKKSILFIEDTSRMS
ITDFDRHLEALTQRDDFCTVRGILIGRFQKDSGIDMDMLRKIISRKKALDAIPLFANVDFGHTTPHCILPIGGMIRVNVD
RKCITVQLHSSVEQLPE
>SEQF2545_AGK84336.1 GTP-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKGQDVILCDGGRHFSYKVLPRVVIVGRPNVGKSTLFNRLLGRRRSITSNTSGVTRDSIEETVILRGFPLRLVDTSGFTV
FSEKKASRQHIDTLVLEQTYKSIQCADKILLVLDGTCESAEDEEVIQYLRPYWGKLIAAVNKTEGGEEVHYNYARYGFST
LICVSAEHGRNIDALERAIIQNLFSVDERRELPKDDVVRLAIVGKPNTGKSTLMNYLMRRTVSLVCDRAGTTRDVVTGHV
EFKQYKFIIADTAGIRKRQKVYESIEYYSVIRAISILNAVDIVLYIVDARDGFSEQDKKIVSQISKRNLGVIFLLNKWDL
LEGSTSLIAKKKRDVRTAFGKMNFVPVVPVSAKTGHGISDALHCVCKIFAQLNTKVETSALNTALKDWVTSYPPPRKYGH
VSLKYLVQVSVRPIEFLLFANRPDRIPENYVRFLQNRIREDLGLDSIPVKLTIRKNCRKR
>SEQF2545_AGK84337.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRNVFVGALCMCGMSFVFSDSVRSAAAAYFSHFSWVMPERVVQEHISWRYKALKQYHMEVDCDVYAYRGGRVFPRVSGMG
VIDHTNIPHALRIFCEKMTDSFMKKKIDPHLCQRERKFLPHYFSFRMGKLPRICAVVFAQPNVMQGNFLTVHFKLNVENE
DSRIIEVTVAKEQENWKLFQFLFKEDRAHLAVL
>SEQF2545_AGK84338.1 segregation and condensation protein ScpA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MWMDESPVPVQEFKLSQFEGPLDLLLFLIKKNELSICDIPICEITAQYLQYVDQTVSPDLRGLTEFYAMAAVLLYIKSCM
LLPMELDLDGEDIEDPRQSLVERLIEYQKYKQLCKLMELYECEDMWCVERKKTQHLFLSPAEVPLLHGDVRDLLMLFTRL
VRKTPQWIMDLYEEVSVNEKLTLLSELLGVRGRCVFTELIKQPSRADVVCAFVAILEAAKTHLVHISQPEFFGPITLYAR
EVSPKVQDVCHA
>SEQF2545_AGK84339.1 recombination protein A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSKALKGDVPVSSSFEEKMKALEAARLQIEKQFGQGSLMKLGKDDAVQGVEVIPTGNILLDEALGIGGYPRGRIIEIFGP
ESSGKTTLALHAVAEAQKRGGIAAFIDAEHALDPQYAKDLGVSVGDLWISQPDTGEQALEIAESLVRSGAVDIIVVDSVA
ALTPQAEIQGDMGDAHVGLIARLMSQALRKLTSIINKSKCTLIFINQLRMKIGIMFGNPETTTGGIALKFYSSVRIEVRK
VETLSRGDEEAWGNKVRIRIVKNKMAPPFRKVETEILFGKGFSAFSCLLDAAVKQEIIEKKGAWYAYREEKIGQGRDNAV
GFLQQNMDITLEIERAVRTKLFPKQAFISSFQEHRPALSLEASPAESDAKTLRRSASRGAGASSSRVQEGSAANDHFQDE
STTAKLL
>SEQF2545_AGK84340.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDRFFCTVWVWSVLFGACTSQTRSSFSLNADGLNSSGVAHASEHVSHAAAMGNEAGAADASVSESPASFSPGRGSAWVQG
TVGHIPAEHHAALQAFFDTEEGMRITDALCTGDTYAAFNELEALYDPSSETDTARSRALHAYVRALLQGIRLAPRVAPPT
HVGVSATLQYRDSVWPLQRGRFTLCYQIGPEHGDVMQVTLCADTQGVLFFPFPSAALSQEVTLSFDTAALVHAPSLCAQD
SALQERPSSPEPVVSTIPSPEGEENSAAGEPALANLVCRVAAPSSDPKQHPVRRQVSTTICILDYGKTGRPLTHENLTAT
RLLGGLLKRRFVNIGLDSLYGVGKVPDHAVIARARKKFGGNVRRLVFGLTQVRRLERDSDARWKCVLFAQLHVWDFPKGA
YTHHFTAQCTETGDTESQSYVRARTRMGETVLSDVLQCFL
>SEQF2545_AGK84341.1 5-formyltetrahydrofolate cyclo-ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNAKQNARRIASARLRAFRASPTAPAYPAHSLFTAQTAYQRARTVFFYAPLPLEIDPYALAYTAENAGKHVALPRVSGND
LHFHAVTYACTTRPSVSCFTTLCPRTRGIREPDAHSPRLYPPHPSPNTPAQRTLALPLLIVVPALAFSTNGARLGRGGGH
YDRFLARIAATIPAGSYYTLGLCFDCQIMAVIPQEAHDQSVHAVLTETRLISCATARAPAPPFSL
>SEQF2545_AGK84342.1 biotin carboxylase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKTILILGAGTMQAPALRAARELGLWVCAVDGNPHAPCAALADEFTPIDLADSAALVAHARAIRARRGLDAVFTAATDFS
VSVAAVAEACALPGHRLEATKNATDKTRMRACFTRARLRCPRSTFLEPDSFAWDTPPGHARLCSHLHSAGLSFPLVVKPT
DNMGARGCTLAQCKDTLINACAVARQFSRSGRVIIEEFIVGREFSLEGLIFDGTLYVTALADRHICFPPSFVEMGHTLPA
ALCTQDAQALIDTFHNGVRALGLTHGAVKGDLFLSTPSPTKTPSTAATPNPSAPYTPEAVLGEIAARLSGGFMSGWTVPY
ALGFDVTRAALHVALHGPSAAASAATASVAPPPTALTVLRTQLTTLSPLPEKSPYASAERAWISIPGVIHRIWGLADAQQ
IAYVKNVFVRMQEGAAVRFPRNNVEKCGNVLSQAPTRAQAIAAAETACRCIVLRLVPAHPATDAFLARKRSAESAASPAL
QDADSEYAASAPHPFGQESIPDIVCDASGRFFTSEVACAPLVRTGLFLIPEPLVRADARDVQGRSIHALCTLALKVEPAL
EPALCFARSQNLAELWRALIRGGIQGLLYAFDSFQLS
>SEQF2545_AGK84343.1 putative nicotinamidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRAFFLVDFQNDFCDPRGALFVPGADQDCVRVAEFLRVHAAHVDALYVSCDRHPRMHVAHPCFWRSLTGDALGPFDTVS
FERLRSGACVPVRVGYVQTVAGYLAFRAYTGKGPLYLWPEHCVRGSWGQAVHPLIVEAVRFWQRAHRTRHPQFFFKGENP
CVEQFSVLSSEYPASQGTADSLFVKRCQMLRAHERIFVAGEALSHCVVCTLQDMQRAGVLSRVSLLKDGSSVVPGFEQKT
AASVQTLCAQGLTWLRMTEAAELLRTRSIFSGTEHQDS
>SEQF2545_AGK84344.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGGWCEGEVMCRLRRSVAGGGALFLAVLWGLCTDANAAQVFVSPRVGQVGVFVWGKGANDANGATGTKRTDILAFTPTLG
LSVGVSAENGFTFVTQLDAGLSTLLFRAQFLLGWVLRMGERAFFLPSTGVDIMSTKDKIVGVPVNLDFHFFFTGVVGLSV
GVASGVGIPITANLEQCKNGAGSTDLKWEQFLQKYCLECPLTVQIGPVFRV
>SEQF2545_AGK84345.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRRLLACSAGVLCFSQLGALELFLSPKIGITSVYQFGSNGGSDGTSSGKGVSFDRLIGRVDLGLILVNGLTISASAESSL
TNVFVRAQALIGYAVRVGGLRAIVSSGVNICGDSCATSEGESSAWYSKLLYSVPLNLEVQYYLTSFAGVAVAASTAVGVR
DLNFKEFTLPLSLTIGPTFRV
>SEQF2545_AGK84346.1 hypothetical protein TPFB_0700 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVMAAAPLQNLCYDGLLQVTSGGNISLPVPSNQVIYAHFEHVDATPAEQGQAGVSVSELQILDALVERLIVQRRVAAEAA
DMAVQKRQETLLRAAELFSQKQVDETKRRGESLPYTSVEVQGPELFDLRA
>SEQF2545_AGK84347.1 putative DNA-directed RNA polymerase subunit omega [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIFPMQQLIEFQGNIYEITCAATRRAFQLAAVCDPVLDELGGKVVSAAAQQVFSGTVDYRIEPQELG
>SEQF2545_AGK84348.1 M23B subfamily peptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGAERVGRAPGVNAKRAVQTQGVQSPSVKRSVRWVRGLCEVLLFSGVFVSAVSFLLHSAAVPPPERQVVPAHFERIAMQF
PRQVSQGACAMATFSLVALQEKDKAHTEVHLVLRTPAGKEAKTVRAFALPPKGIAQLGTDAATAGVSRAGSQDVTHVALL
GISIFWEPGDWMLEAQVRVPGGKPYVRRAPLRIEKKEFPREELRLDRKNTAIAQDKSERKKVQRERLKALWTVTSPQTRA
FLGPFRQPVESRRCTSVFGQARVFVYTDGTRSAQYHWGKDFGVPVGTAVYAAGTGRVVLAEQRTTTGWSVVLEHAPGLYT
AYYHLNELLVKKDTYVSTGTLIARSGTTGFSTGPHVHWEARINSTPIDPECLLAPPFLTHLPKNALRKLQPTGETQPGTP
LPKDTNGLPG
>SEQF2545_AGK84349.1 single-stranded-DNA-specific exonuclease [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRWRAKALDEGRVRELTARYSCSALEAAILVRRKVVDADALLFHFERDLRYLPGPFRFHAMSAAVDRLRLAHERKEKVL
IFGDRDADGISATTLLFEALCAFGLTVCWRVPVADEPYGLSCNAVDEHAAAGGTLIVTVDCGISNRAEIAYARHRGIDVL
VIDHHAAPETLPDAIIINAKVPGAGYPHEFLSGCATAWKVVTALRFSTSGWYQRPVVLLHVRPVTGAYTIEAVKMCNMEV
VDRLSETVVPRMLLPSHTRLGAFLEGQEVFVWDEQVVRTQLAKVFGGEFPWRFTDVRPRMAAFFPQCERASLLRMKDFSR
IGRARSKPMEEIESFINLFITFVQKDTQLYRGAADELQLVAISTLSDLMVLAGENRIMVRYGLQAMNEAPRVGLRELFAI
QRLMGKKLGTVEVGWSIVPLINATGRLGCPHRAVELFLMREASQRALQARKMVQLNEQRKKLGRSARALVEPLARASLET
YSNRLAVVCSDKIHRGVTGILANCLSEALRVPCVIICIMADGHAVGSLRSARGYHLFSLLDPLADLFSDYGGHAFAAGFS
IPSERIPQLLHRMELYAATIEFADESAQECGEFDAELDATQMTRGLLTLVDRFEPYGEGNPPLCFLAKRLKIFSASLFGR
TERVHVKLTLDAQVHKWPAIYWGAGEKLAQEFAVGDVVDAVFQVTRNTFQGTCTPQLVIQDLWRSE
>SEQF2545_AGK84350.1 bifunctional membrane carboxypeptidase/penicillin-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRRVCYLYLVLLCGLLVGGAALFGFLLASIENIKQSERFTRFNPALPTRILDIRGDLITEFSSDEKREIVSFADLSSHLV
HALLTREDRSFYTHHGYSIKAIFRALVGTLTGRALGGGSTLTQQIAGLLYSDRSDRSLRRKIKELWWALHMERRYSKNEI
MELYLNRVYFGGGTYGVGAAARFYFGHSVRQMSAAEAALLVILLSNPAHYNPFEYPNRAQDRQRYVLHEMTRLGYLSEQE
RDESYEHYWAHFDYTRTTSSAFYARADKARWFSEYVRRQLDRMMYGTMNLYQDGYTVHTTCDLRHQLVAEQQVEQTLEQA
NAHVQKSSLTHVARRELYSNISELLGLVFNVPQLHVGDRRMKAKSGAYYRSTLSPLVNVMALMFGLDNLKTLSDKGASLV
RDEIARKRVEGALIALENDTGYITALVGGSRFGASNQVIRATQGLLQPGSVFKPLVYSAALDSKKLTMATQLHDAPQVFS
RNGVSYIPNNYGGKWQGVVLAWKALAQSLNIPAIRVLDMVGFDAVIQRAATLLHITDRQEIERTFPRVYPLALGVVALRP
IQLARAFAAFGNGGKAVEPIAVRSVEDRLGRVILDPEREVRARLRAQGAATQLISAENAALMTNMLEKTVTMGTLAVASE
RGRAFTYQDPATGRSFVMPVAGKTGTTQNWSDAWAVGYSPYYTAVLWFGFDKGDRSLGLHSTGATLAGPPWARFMRAIHQ
DKPHRAFVRPETGLMYQAVCAKSGLLPTPYCGDELVSLSFLPGTVPERFCSYHESGKMLEELAKERLKESGYSTGFWPAV
SEEGLHIDPRVFEDPPLGSPGVQGEVLVPSNPFAPVHPQEAPLFDAPHVPVPSASDPSRDAPEEESEDVQDDPARGVQSL
DTGP
>SEQF2545_AGK84351.1 hypothetical protein TPFB_0705a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHRAVCAVDGLVPLALKFSPFCVPLLAHASRLLPVSGVAVRSVGGGSCALWVLACLH
>SEQF2545_AGK84352.1 hypothetical protein TPFB_0705b [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRCRRAPPLCGTTVGRGVRTRLKVLQVEPILGAPAAWFPSHLSRGRYVVGPV
>SEQF2545_AGK84353.1 M23B subfamily peptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMRLCPFSPFSFLLRVRMVRAAVCSCLCVCVAHPAVCGPYPLIAQLQGQDALFRQYSDDVRAARVALAQGKRGNDLPLRF
YAYRVKKADTIIRIAARCGIPYDAVASLNRIETLHTPLEGRTLLLPTVPGLYVSADPHLPLERLIYALIKKGQGPSFFLS
LPGTAQTTHTREKREVVCAPQALFDGTVRAFFLKPFYRFPLASGRLTSGFGARKSPFTGRLSYHPGIDLAAPMGALVYAC
ASGQVATIAYNRLYGKYVILQHTDGRHSLYGHLSAVRVRVQQKLSVGAVIGNVGSTGASTGPHLHFEVREAGVPQNPERF
MEKFR
>SEQF2545_AGK84354.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRGTPAYHAVSGVPCSACTCTQVAVQLALSWRGSMGRLKRCEVRRRPCALWAIVRVARIGALAAMLAVLSFALGCALVYP
LWALAVHRPRVFSVLSGLLYGGGAVLWGLRRVCNALSYARVRRAGRRAAAQEPCVLVQAGEVGAMGLSSSAEVRPAQEC
>SEQF2545_AGK84355.1 hypothetical protein TPFB_0708 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDVQERRFSCAAVGASLKVPAIAAGAAFFLSIATAAVARNARVYVSVARATVLALGAGVTAYALRALLAYVVPDLLVQED
GKMPIPHVDLTLDDVVEPSFASPGGDVVQETDDSFDSLIPTGELGELGYSFSPSTPSFEDKTSDLVGDVLTDLPETKRMA
RAIRTVLSQDT
>SEQF2545_AGK84356.1 DNA-directed RNA polymerase sigma subunit WhiG [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGNTAFEQQSEEELWLEYRRTRSAKIREYFVVQYAPLVKYVASKIAVGKPGNVEFDDLVSYGIFGLFDAIDKYDPEKNIR
FNTYAVTRIRGAIFDELRSIDWVPRSVRQQTRQIEEAIADLEARLGRAATDTEIACALNIELEEYHQLLLKVSGTSVISL
ADSKFSGDERDHVSVGDSIEAPASLNPDVIVEREEIKRIIAEAIRELSQREQQVLILYYYEEMTLKEIGKVLKVTESRIS
QIHTSANLKLKAKLTNIKKGIR
>SEQF2545_AGK84357.1 hypothetical protein TPFB_0710 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNTRFDQIRRDMQKRYEEDSKRVCVSACAKTLDKALEAAAVQLGIPKYRVEYEVLERGAGSFFSFRQKKWKIRAYESSSL
EFAAGNVSAPHDSHRDVSSSPNTGHDGAAFVLCKKEGVFLKITAPLGKGRKVSLASVQEKFRARGLALPPADTLKVLIKN
ATNSYVHVSSFERIPAHDAMLSVEIRENDMKAFVTATPPGRNGADICADTILSFLRSNRVVYGIDMERVNSFQDCPVYHE
PYLVARGTPPKDGENARISYHFETDRTRVHLQELKTGKINFKELNLIHNVVKGQPLAQKLPAQRGTPGKTVTGTYLPAQS
GKDVSIPLGRNTALARDGLTVIAETDGQALLSRRGINVEPIYVVEGNVSVKTGNIMFLGTVLVHGNVEDNYEIKASGNIE
VRGTVGKALLDAEGDILVGQGIVGKEEGCVRAGKSLWAKFIQNCASVEAGDLVIVSDGIMNSHVIANRKIICRGRRADII
GSNVAAAEAVYARNLGSQSGGNDTQISVGFDPHRVRRLSMLQEELHAHERKLSDLSLNLQSLENLKRARKELPPDKEALE
TSLHEEKISLEQLVQQSRAELEEIQASLDASPIEGKISASGQVYSGVKVTIRDVSEEVRADSTAISFYLRNGLIRYGQYT
GEQDEDYKRAPSGYAY
>SEQF2545_AGK84358.1 hypothetical protein TPFB_0711 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLVMSITFSFVAVALLVYFYVKVRTSFSPDAYAKTMQQEVIKMIRDIRYEADIAVQMLEKKIGECNQVVRTIDRKLTLLN
EEILKEHTARTLFRASGAGQETREEVCARPEHRSAPSRAGSSAAKPTPTKRGTIEVYNEKIIRDNGLRAESPLLKDAIIA
LSEKGLAPEFIAEKTGKPLGEVQLLINLSR
>SEQF2545_AGK84359.1 putative flagellar synthesis regulator FleN [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVITVAKRDKRIADQAEELRDLMQEKNARERVERHQHRTRVVVVTSGKGGVGKTNIATNMAIAYGYMGKKVVLIDADLGL
ANVNVIMNVVPQYNLYHVIKKQKKMSDIIIDTNFGIKLIAGASGFSKIANLNEEERAAFIQELYSLSETDIIIIDTSAGV
SKNVVSFVASADDVIVVTTAEPTAITDAYGMIKIIATEVDNRDMNLKMIVNRVNSAAEGRRISERMIQIAAQFLNLKLDY
LGFIYDDTSVGASVLRQVPFLIHEPRGKASVCLRHIVAKLEKTEIAETGGLSGFIRRIFGREWE
>SEQF2545_AGK84360.1 flagellar-associated GTP-binding protein FlhF [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MELLVEVAPTKEKAIEKIRKKYGDRVNILRTQRNNRSFFFGLIERVSVEIFFSVNSGSQSSVHEIPSVQSRTRVSAARVE
DTEAEKIKILESAQRINAKIAQQVEPLISAAKEKKTEKVPTSPEAVHALTQTLEGMIQKITNSAPVVIAQELQSIQRIEL
LLEENDFSFSFIRKSIARLKDELSYHDLESFEKVESTVLRWIIESVHIQVPPICTGTRNIVLVGPTGVGKTTTLAKLAAF
YFVTEPKRTGIQPRVKIITTDNFRIGAAFQMERYCELMGLDLCVVQAPVEFLTYMTLYQQETDVVFVDTEGRSPVDGQNI
ERMVEYFRAVKNFELEVYLTIDAGSKANDLREVFKQYALFEYRALIVTKLDETTSIGNLISALSEARTPITYITTGQTVP
SNLEKASVNLLLSKLKGFKLLAEEMGNDYGDYGSKER
>SEQF2545_AGK84361.1 IIISP family Type III (virulence-related) secretory pathway protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAHGKSAFFTTDAFVAISVLVVVFSIVVPLPTQILDALMAFNLIFNLLILLMVLFVEKPTDFSVFPSLLLTSTVFGLGLN
VSSTRLILTLGDRFSGYMIRAFSSFVVGGSGTQGLVIGFTVFIILIAVQAFVITKGATRIAEVAARFTLDFNATKSMSID
AEYNAGVITEEEARERKRQIQREADFFGAMDGASKFVSGNVKIGIFITIVNVIAGLIVGVIFRREGFQAALQTYTNLTIG
DGLLAQLPSLLLSVATGFIVTRSSDQGSFGQNVQEQFSKSALVYFIGSGALIVMAVLPGFPHSILFFMAVCFAFVGLQLR
KRERVHVQEHEMQKSSDKKGMQQTQDSTSEMGPIVPLDPLSLELGYGLIPLVDKEKGAELLSRITVIRKDAALDLGLVAP
KIRIIDNMRLDPSSYCFKIQGLEVARGKLRLGWFLAIKSGQVTEEVPGERTIDPTFGLPAVWISEENRDRAERVGYTVVA
PSAIIATHLTQVIRTNAADILGRQNVQMIIDALRKEYPAVVDDVTQKCPLGKIQKVLQGLLREQVSIRNTVAIFETLADF
ASTSDTVPVPILIEKVRQRLGRQICLQYADEQNVLHVMRLDSSLETFLSEKIALTVDSLSILTLSLDEQRQVLQAVRTVF
VPTRQEGYIPVLLTTDTIRSAMWNLFFSDRIEIAVMSYKEVSTDMRIETVGVVRIEESDVDAFVRKQ
>SEQF2545_AGK84362.1 IIISP family Type III (virulence-related) secretory pathway protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIEQEGTFPLPPFIIDLQWFAAEDEGRSEDPTETKLRKAREEGRVPKSQDLNGAFVMLFTSTSLFLLAPFILRECIGVLR
FFFTRATTASIQNTGWFFVFVRYFMKLALPISFVALVSGVAANIVQNKTVLFSVKSIRPQFKKISPDVIRFFKRSFFSTE
GLFNLLKSLIKITAIFFVSYFTIRNDLFMFVSLLGVSLTQSIFYITSLAGKVLLEVSLLLVVFALPDYFFQRRQFIDSLK
MSRQEVKEELKEQEGDPLVRSYVRKQMQSLVRESARNTTDADVVITNPTHFAVAVQYEPAYMTAPTVVAKGSDGTAYRIK
RLAKEAGILIEENKPLARALYTQVAIGREVPYEYFNALVLIFTKLDKFKTHAQRKR
>SEQF2545_AGK84363.1 IIISP family Type III (virulence-related) secretory pathway protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MERSFDALFSQASLFFLAAVRVFALMFTVPLLSVRSVSRVVRVALAGLIAFLVLPLAYPAPMQVREFSAYYVLLLLGEGL
LGILTGFFISVIFTTFSAAGQFFSYQMGFGTSEMYDTFAQIENPLMGQFLNFVAMLVFLQIKGFQILFLGGVLRSFQAVN
CFVFLRKQEALLLFFTKALSALFLHAMTIALPIMGALLLIHVSMGLLTKAAPQMNLLSEGLPLTIVVTFVLLSVILPYMI
NLFVSILFGGFEMFEQLLVKLGKAL
>SEQF2545_AGK84364.1 IIISP family Type III (virulence-related) secretory pathway protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTQGAVLGLIREGVFQVVLLVAPVLCTALVVGLIVAIFQAVTSIQEQTLTFVPKMLTILGMIALLGGWMLTMLQNYTVRL
FDIIPQLVRSGPV
>SEQF2545_AGK84365.1 IIISP family Type III (virulence-related) secretory pathway protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRARACVRRALFFVSLFFFPLFAQDARGGVERGVTGINAERPASRIPFINFDIREPQTNREVAFSVQLLLLLTLISLAP
SILLLMTAFLRLSIVLDFIKRALSLQQVPPTQVLHGIALFLALFIMWPVFTEIYAKSFKPLTDGQVDIQTAYTEAERPLR
VFMYRQMAHDPSSVRLCMSMAKLPKPDTLADVPTYVLIPAFILHELTVAFQIGIFLYLPFIIVDMVVASILMSMGMIMLP
PVQISLPFKLVLFVLVDGWNLLIDRLFHSFL
>SEQF2545_AGK84366.1 putative flagellar biogenesis protein FliO [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKTLGCVLRKFSRRENVLRTFNCSLRIVPRCATLFLSVHVFLHVSFELWAQQQGVDVSAVSEAVSATSAQKEQPAPESAR
DTREDAFPLTPAEQAFRFDAAPVARDPSPSVFSLLLRFSLVLCVVCAAVYGFLRLIRRSAFLSSAHDPFLKRLACLPIAP
GRAVYVVGLAERAFVLAASDTCISLIAEVKDKELIDTMNIVADEQGTDARADFSQMLARLLPARVTGKGKPLVEADFLAD
TRKKLRRIPRNDSEESAAQDAL
>SEQF2545_AGK84367.1 bifunctional chemotaxis protein CheC/flagellar motor switch protein FliY [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSDGSISQAEIDALLSGVEMGAGDSPAAGASFSGGGLSSAQSELLQSFCQANVGSFCPSLESLTGKTVSISPPRVEISSK
EEFSRVIPDMLVATVIDFEGEFAGDHLFLMAPEFAQKLVNLVSHEDNDQIDDMGLSVVSETITQYVSAQLSTLEARNVQN
VSVAPAESVQVPKAMVRFPPQRLCVFTYTVELDGTSYTLWELVSEQLMVRIIERMGGAMQRPQAQVGNSQMGGVNMQMGI
GAASPSVQSVQFHPLQNAAGGAEQGNIGLIMDVFMEVTVELGRTRMMIKDILGMGEGHIIELDKLAGEPVDILVNHKLIA
KGEVVVIDENFGVRVTEILSPGERIADV
>SEQF2545_AGK84368.1 flagellar motor switch protein FliM [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTEVLSQDEIDQLLTAISSGDASIEDARPISDTRKIKLYDFRRPDKFSKEQMRTLSLMHETFARLTTTSLSAQLRSMVHV
HVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPSITFSIIDRLFGGTGQAAKVQRDLTDIENSVMEGVIVRI
LANVRESWTQVIDLRPRLGQIETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRR
SSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIGNRKKFLCQPGVVGKKIAAQI
LERIESTSQEDFEELSADEEELYE
>SEQF2545_AGK84369.1 flagellar basal body-associated protein FliL [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAEKDSIGDIADDFEEQLVAPAADRVGFLPGLLRWVAIAVGAVIFIVTVVTATALVLAKQGSSHTAYPVSQEFRESRELL
QYYESVGLIRTNTADALPGTVVVSVALGYPLNDKTAQQELSARLVELKDFLRSYFQRKTLSELRPEHEQKVKIEIRNEIN
DNVLSRSKVKDIRFTQFDVLKP
>SEQF2545_AGK84370.1 Mot family proton (H+) or sodium (Na+) transporter MotB [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLMARKRRAPRGAAQGWLTTYSDMVTLMLCFFVMLFNPTEVDITVLQSIAASIVGDPTGGGVSASSGRLADLGNTVNTLP
SLEKGQKLATALKKAVSLFAPEIKSNKIAVTSDERGLVISLTSDSFFYPGSSDLNVEESREALLRVAQFLSDHALAGRRF
RIEGHTDSVEVPEDGSTDNWELSTRRAVRVLHYLTDFGAQENRFSLAGYADTRAKFSNESPEGRAYNRRVDIVILDEGHF
>SEQF2545_AGK84371.1 Mot family proton (H+) or sodium (Na+) transporter MotA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDIASFIGLFGGFAIIIFGAVLGGSARGLFHVPSLLITVGGSYLTLFLTYPLSYAVGVFRVIARVFHAADFHEREIVQRL
YALAEKSRRTGLLALEEEIQDFDDDFVRTGLRNVVDGVDGDAIKALMESELTHMEDRHNTWISLLNSWAALAPGYGMLGT
VMGLIGMLATLEDKSSLGSNMATALITTFYGSLVQNWFITPVATKLQYQHDLEVKSKEMVIEGVLSIQAGDHPRVLAQRL
LTYLSPKMRKELEMELIKD
>SEQF2545_AGK84372.1 flagellar protein FlbD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIKVTRLNGNENWVNPHHIETMRCTLDVTLQMLSGKCYVVRESVQEVIDKIVSYRRSIGCLNDET
>SEQF2545_AGK84373.1 flagellar hook protein FlgE [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMRSLFSGVSGMQNHQTRMDVIGNNVANVNTTGFKRGRVNFQDLISQQLSAAARPNEEVGGVNPKEVGLGVLIASIDTVH
TQGALQTTGINTDVSIQGSGFFVLKSGEKTFFTRAGAFGVDNAGTLVNPANGMRVQGWMAQDVAGERLINSSAQTQDLVI
PIGQKIDAQQTSTVHYACNLDKRLPELAADANEADVRKSTWTTDFQVYDSFGQQHTLQINFSRVPGTNNQWQATVAVDPG
TEVDTQTRVGVGTSDGAANTFIVNFDNFGHLASVTDTAGNVTGPTGQVLLEASYDVVGANPDDAGQVTRHAFTLNLGEIG
TARNTITQFAERSTTKAYRQDGYAMGYLENFKIDQSGVITGVYSNGVSQDIGQLALAGFANQGGLEKAGENTYVQSNNSG
IANISTSGVMGKGKLIAGTLEMSNVDLTDQFTDMIITQKGFQAGAKTIQTSDTMLDTVLSLKR
>SEQF2545_AGK84374.1 flagellar basal body rod modification protein FlgD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVQNTNMRFEMTAAERTRLEMDVRVINKQLEAGARSAKRELGKDDFLHLLIAQLTHQDPTAPMQDTQFIAQMAQFSSLEQ
MANMSAQVEKLGTLFGNTEALQAVGKMVEVTEADNTVRGLISAVTRADKPQVRVGSHWYEWEHVKVIADPSAS
>SEQF2545_AGK84375.1 flagellar hook-length control protein FliK [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MELRGLLARAIGIGVAESAPAAQETISVGTSCAAAPCSFSQSLHDHMRGAAPQRVSLSPASAAVHERVREEADEQQTGSG
TQQDVFTEESLSDVFLVAYETGLRAAQEAASGVRPFDYVRAAQEASGGASWPSAPEFLVAERQATSVTPRSVVPEQPLSG
ERGRAARPAGLSRAYAQRVPETAPHVQDLCGQESGEHLRESAGARGLRGGSLPSGAAPALLREQGSEATYAASSESEVFD
VIFDAEVRQRLVAAAIRGEPVLQSGGAGSSFGGKAGASHASAAAGVSAGAAFQGATAYGQVRHGDSPQELRSFSDARFTV
LDARRHSRGAGSGVSSHAGAVLPAAQAQLSAADVDAGAEEHGTESLREGERAGVERAFEGVAHAREETAQSQGIRGFATT
QAALSAHIRAHSAELAQSGRVVLRDHGRGYIDIALKPEHLGAVSIRLALSENKRVVGTIHVASQEAFEAFQENLGDLARA
FEANGFDAAQFDVQWFGAGAHAEDGHLASQTAAYAAAQRLGGAGVEPVVQEVHWHAQGAALTIDVFA
>SEQF2545_AGK84376.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARASSPLSSMHSPHSLPFSAHCAARLRKKTCQSGSDASFQYKAHEKFSTLPKAPARRFFPVQYFPVSPDKRWILGYLSP
PSMEKETAGILCSYTLFHSALVLALSLAHGRTQVPPSSTLSFLTVIVLWHCLLFFFLVAYSREPADTTVPFKPLPEQTAP
ICAAASSDCKENRTALKTLNTATHITLIRASAIPIVGFLLKFHALAGLSYFLVAGLSVLFLTDFIDGKIARARRETSRVG
ETLDAASDYALIGLISALYYQSGVVPLWFFVLIITRLSLQTVIACVYALFGHPMTGSTAGGKATVAVTMLLYTLELARLL
LPNLARSNSGARFFTGAEILAGFVIFTGIVEKLYLGVQHRPGRSP
>SEQF2545_AGK84377.1 ADP-ribose diphosphatase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDEGRETVQPAHRAKEEKKQDAHLAWEVRKRHEACRLRVFHVQELESVSPRKTVRRFVTLTAPEWVIVVPHVMERAQRFF
VMVRQWRCGSQTVCTEFPGGVIDAGEHPEAAARRELFEETGRRASSLAHLGTIHPNPAVLENRVHIFSAECTPEVREPQL
DTDEFLERCVLPVHDVYERMGRAPFDHALMGAALFLFLRAHPLSSL
>SEQF2545_AGK84378.1 bifunctional methylenetetrahydrofolate dehydrogenase (NADP(+))/methenyltetrahydrofolate cyclohydrolase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDARLIDGKQAAHECTARLATRVQALRAAVGTAPFLAAVLVGDDPASCTYVAAKQRALARAHLRGETHRLPAHASHAQVL
ELIARLNEDARVHGILIQLPLPAHLDAARVCRAVAPEKDVDGFHPLNCGALFLAQPGFVPCTPAGIVHLLRRAQVPLAGA
RVVIVGRSAIVGRPLAVLLASPGCDATVTLCHSHTRGLADICVQADILVAALGKARFIGAPFVRTGAVVIDVGIHHVPDA
TAPRGRRLCGDVDFDAVAHKVQAITPVPGGVGPMTIAMLLHNTLCAAEYAAGMIPPFRAALYADLDGRAAGDVPH
>SEQF2545_AGK84379.1 hypothetical protein TPFB_0733 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRTFRAWQCVGALCALSPLLPAYSSEGVREVPPSQSPQVVVAYEPIRPGDQLLKIGIVAGCQLYIARGNGTNGPSSSGT
NGNGNGKLLGGGGFHLGYEYFFTKNFSLGGQVSFECYRTTGSNYYFSVPITVNPTYTFAVGRWRIPLSLGVGLNIQSYLS
KKAPGLIAEASAGLYYQYTPDWSIGGIVAYTQLGDIAKPATSSRAVGLATIDFGVRYHF
>SEQF2545_AGK84380.1 purine-nucleoside phosphorylase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSIHLGAKGEDIAPRVLLPGDPLRARFVAERFFHNAYCYNEVRGMLGFTGTYKGVRVSVQGTGMGLPSHSIYVTELFQDY
GVQKAIRVGTAGGLQEEVALKSVVCALGAATDSAINARRFSGMHFAPTASWSLLRTAVSVADEMGTGVQVGNVISSDVFY
DESGSWRLWARYGVLAVEMETAELYTLAAKFRREALSILTISDHLVTGAVTSAQERERSFTQMIEIALEAIIQ
>SEQF2545_AGK84381.1 glutamate synthase (NADPH) [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTSVQNVVSDAKTCDVPVESEPEARTYRPHALLQEEACQRLAQLQGKELKMKDRTQIPLQRMRMLPPKKRSLLMQEAALG
FTEQQALVESQRCLNCKTKPCVKGCPVGVPIPEFIACVQRGAFKEAVDIIKTTSLLPAICGRVCPHERQCQFQCTVGKMF
KDVSKAVSIGALERFVADWERQHGQITVPYCAPSTHKKVAVIGSGPAGLAVASDTARAGHSVTVFEALHKPGGVVTYGIP
EFRLPKEVVVTEIETLKKMGVTFRMNFLVGRTATLEQLFSQYGFDAVFIGTGAGLPRFMNIEGEELCGVFAANDYLTRAT
LMKAYDTAHADTPVYAAKSVVVVGGGNVAVDSSRTALRLGAEQVHCLYRKTRADMTACVEEIAQAEDEGVTFHFLCQTTR
ILGDEEGNVRAVVFRDCQEQIDAGERVFLPCGDAECELAADAVIVAVGNGSNPLMAKTTRSLAVSERGTIVVDEDQRTSI
PGVWAGGDIVLGAATVIRAMGQGRRAAASINAYLAQKA
>SEQF2545_AGK84382.1 ferredoxin--NADP(+) reductase, subunit alpha [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFSILEKKQFSPQVFYLKVHAPDIAKNRAAGQFVLVQLDDEYAERIPLTIADAHADEGWIALVIQTVGATTMRLCEKEVG
DSISVVLGPLGNPTLIENVGTVACVAGGVGAAPLYPIAQAHKRAGNHVIVILGARNRDLIIFEEEMRALADELVIVTDDG
SYGRKGLVTEPLRELCERASCPQEVVAIGPPIMMKFCAETTRPFGIRTVVSLNTIMIDGTGMCGGCRVNVGSEIKFVCVD
GPEFDGHQVDFESMMRRMRAFQAREAHDVHCCKMKHHAGR
>SEQF2545_AGK84383.1 hypothetical protein TPFB_0736a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPCATELKKGFSLTNLHSLYYHPSLREFGRRRHGCVQHSRKETIFSAGVLLEGACT
>SEQF2545_AGK84384.1 sugar ABC superfamily ATP binding cassette transporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRNTGSATYARIGGVFLSFFVLLPVFCHGSKEKGKEEEPVRLSVLIREKHYSSGLQNVFTKLELEEGIAVTVETIQDDQY
PTVLHARLADGTAPDVVEVSLPSLHALDPYLYFVDLSKEAWIPDLLIPPTDPYGKTFALPLNCAVSINALFYNKDLFDRY
GISEPKSWNELLESCALIVKSGISIVPLALSTTESFPHTLLADAITKVLGEQGARDLVKRATDDSIDWTHERALYPVLGA
YLELFKRGYVNKHHRTARVREIIHDFTRDRIAMYFGSHLVADAIIKERPGINLGACVLPITENAQDVLTGSLEVQGLAVH
KKSARVATACRALSVLASAAYQNSFFEEHKGLPAFRNTTSAVIPACLSALFKSHIEKGKVIQAIDAYAQAQNTPHRASVF
PDFAAYVTDPAPTAHTMLHRAQTEARRRREPVQKKE
>SEQF2545_AGK84385.1 hypothetical protein TPFB_0738 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSANGAASAVAEALCDARAEDVCVFDVSARCGWADFAVVATVPGLLHGAHRLVCEQATRFGLREVHRKKRGLCEEQWRVL
DFGSILVHLMSAQARAFYDLDRLWQDCLVAR
>SEQF2545_AGK84386.1 LytR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKVLDMGRHGLFLLLIFFMLVITVFAVFFGMKRDPLESSLSSDNILKVLFVIEHENVPISSNVVAYYPATRRAAMFDIPH
NMGLILQSLGRTDGIGSLYSERGIEEYKREVEKLTGINVPFSVVCSLDNFSKLTDLLSGLSVFIPTPIDVHTERAGHVLL
PSGSVSLDGDKMRDYLLYEDEDEGEGESASRKQKAILALLRSVNDHSEFFVHSTRAFSLNRLIRSNVRRADLKKLIGELS
KLDSERLVPQRFSGTKRVVDGKVLLFPSRDGQQIKEIVRQTLAVLASENGTAFERVYALEILNGTESHGLARTTANIYQG
FGYDVVRVDNALEQSVQKTVLVDRIGNPAVAKVVAQVIRCQNIETTSASLDEYGVETGIDFTLILGKDFNGYLVKEGT
>SEQF2545_AGK84387.1 hypothetical protein TPFB_0740 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYLPQFVSILSRVDSTGREPLPSFSGVDDSSCSSRFLSFLGQAQMPAFSFVSADMTALIARVDAYARAVLSPPRYEHSRR
VAEFGCMLVRRYALEAQLEPHVYCAGIAHDMCREHSEVFLLRAAACDGFPIDVTERGTPLLLHGRAAACVLAQEFGVQDE
VLLSAVRWHTFGCEDFGVLGKILFISDKIEPARAWAASLRGAVSTLTLDALAAKVVSASIVCAERKRTTPHPRTCAMLRA
LGKDVSQPA
>SEQF2545_AGK84388.1 putative nicotinate-nucleotide adenylyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKLALFGGSYDPVHLGHLLLADAVHRHAGYDRVLFVPTFVSPFKEKEGSASAHDRVRMLHLAIGTTPYFSVEECEIRRGG
ISYTAETVQHVREKYGAQLEGKLALVLGEDAARSVPHWHAFDSWSTHVDFVVGARPVTSGDGGNVERATRTLQSFPFPWV
SAENVALPISSTYIRTAIQRGRSWGYLVPSPVREYIIARGLYRS
>SEQF2545_AGK84389.1 GTP-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MASFVDEVLIRVSSGRGGNGCVAFRREKYVPRGGPAGGDGGRGGDVVFQVRRNMRTLVHLRYGRVFRAKNGQDGEGARRF
GAKGHDCVIPLPPGCLLRDAQTHEVLHDFGHAHEGCVTLLSGGRGGWGNYHFRGPVQQAPQRAHSGQPGQERVVHVELRI
VADVGFVGLPNAGKSSLLNFFTHARSRVAPYPFTTRIPYLGVLRTGDGRDVILADVPGILERASQGVGLGLRFLKHLTRC
AGLAFLIDLADERALHTYDLLCKELYAFSPVFETKARVLVGTKLDLPNARECLQQLRAQHPSTEVCGVSVHNRWGLDELQ
EAFVRLSDAGAGALRSPVWRNQAPSFMYAQLEDPVCQVRDDFGATVSLSRKRKVRG
>SEQF2545_AGK84390.1 ribosomal protein L27 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARKRGGSGSKNGRDSNPKYLGVKLFGGQHARAGSILVRQRGTRIHPGENVGRGKDDTLFALAPGVVTYLQRKGRRLVSV
CVENRPS
>SEQF2545_AGK84391.1 hypothetical protein TPFB_0743a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSGFRVGSLVFHCGVSRTWFTYVDAGVSQFGASLRAEGSGVCVASRLRQNGG
>SEQF2545_AGK84392.1 hypothetical protein TPFB_0744 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLLEVGDRGQFLSAVASGHAARGTRGGDVVCAAVSVLLRTAVLGLERLGPQIEAADRGFLSFRVGGCPDSALALLCFTAE
FLERGLRTLMQEYPSSVHLCVRRGVVCA
>SEQF2545_AGK84393.1 ribosomal protein L21 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFFGGFVYALIEYKGKQYKVERGSSIVVDNISEVAPGGCIDVREVLMIGGEGLTRIGSPYLEGVGVRAVVGECFRSRKIT
VYKYKSKKDYHRTIGHRQWYTRLTVSDILGV
>SEQF2545_AGK84394.1 pyruvate, phosphate dikinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNIAKSIHFLSNKEALDKRLDRGLLGIRGRQADELSSLGFPVLPSVVIDATVSRSLYGEKLRSALSPYLRKFTLLNRKEY
ADAKNPMLLKVVLSPNLAISNYPVLHNFGLTRDTFAGFAERVGEHFATHEVFFLLKGVFGVLLGIAESEENTKGASEFVE
TLKEIEVFLQGGKSSPSGREAMNRYRALLPDGFFDDAYVQLEEAVRLVSKLLSFEEDGEDGVAILIQPMVYGNYGGGSYS
GRFFSRNIITGEKKLQGQYFEERFDECDAEGSDVNAIKPAYLKQLQDIAWKLEDHSREIREVRFTIEAGSLWLIEQKPVE
AKSTISLVRLLLDLYEREVVDAEYVVKSVKPGQLNEILHPVIDMTSVTGLKSSQGGIIGAPGAAVGRVYFTADSLIEAWR
VAKMGGQDTRCILCMPATYAGDVKAIEVATGVLSNEGGYSAHASVVARQYGKISLVRPDMKIYSDKAVVDGMTINEGDFV
TLNVPYYGESTLYMGAAQLIEPDPETSGLVSFIELAKGFVRSFHVRANADSPHDAELALAFGAQGIGLCRTEHMFFKEDR
INVFRRMIFSENAEERTGSLKQLQKMQGEDFYGIFKVMQGHEVTIRLLDAPLHEFLPHGESEVSKFLEYLEKVCGKGLSR
EELQERISMLSEVNPMLGHRGCRIAISYPEIYAMQVRAVFEAVYRLQKEKISVYPEIMIPIVMNCRELKQIVYGKKIEGH
AYQGIGSIEEEVRLALKAKEVDYKVGAMIELPAAALSADEIARYAQFFSFGTNDLTQTTLGLSRDDFNTFMPDYTMYDLV
DGNPFAILDARVRELIEVAMQRGRLARPDIQLGLCGEHGSRSENIRFCMEVGLDYVSCSSYSVPIALLAIAQAEIENAEK
EGRKPAWRGRSSAKSGGRRAR
>SEQF2545_AGK84395.1 hypothetical protein TPFB_0747 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVSASSFYVPAAVKKNFNALVRHVKGVLSVLDECDPKNNVADQVNLLLCAKEMQSEQVAALLSVLLIDTWGYRLFSYNLR
KVSVEGLGFAQETARWKGVDIVLGYHHPDLGFLAINPKNPSNASLVEGFRKNELLLVYVGKQDRGPLDERIADEVAKGLI
ALIENRKFVVPKEILSGVFAFVSTKKSEGSGKRVRSAKKSGADAARASEGATCDRASSESVSPTARPPAQASAGPIRMSQ
LISVPVSNELFHNGNVEAWKRIIRSYNARYPSSEVIVFYDGERIVDINTLFKWGKVKHGSVIQFAVSGEEIKDLSKLSKY
FKEGASSRFEVFLHGSPDTVLNLF
>SEQF2545_AGK84396.1 cytoplasmic filament protein A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MASLDLPKSPNVFHPEKPSAVGSRNSLAQDYRDQQQEVNQLIEEETNKILHHLNTKLPKEVLERLDVMGGLKEKLYNYFN
QNYQNMFNRYMVTAEDEMLKKVRGFIDREEMKVLNRYTPKEIAILLDEVAGADKFNTGEIEKSMVNMYGHLQGHIQRGVN
ELETHTNSLLRQKVDVGAFVRGENAYAVVKCAFKDNLARPKTVTDVKLSINILDSELVSPIFHYQTTVAYLIKDLISNHY
IDAIDKEIDRVKDELIDQGKEEMSDSSIIFEKMKMVSDFTDDDCENPDSKRYELISRELMEKISNLRAEIDPETFDQLNV
RENIKKIVDLENIRNRGFNTAINSITSILDTSRMGYQYIENFKNARELILREYDDTDISNLPDERYQLRLKYLDNAQLIE
ERKGYEVMLRSFETEVDHLWDVLRTKYDKSKASRFMAKITDFDDLAKVYKKHIKKHYKDKTGEPVYEDIAKVWDEIAFVK
PAETEVERMNRTFVYEKDKMRRKLILMRGKLKGMYDYQYPIERRVMEERLAFLESEFNRFDYLVNPFHLQPGLLLDIDIT
SIKRKKATLDGMANVLNEFLHGISKGFADAAFASFSRRRSTVRADIGQSFASDGSADQKESSGRVAFMDMVNETPALESS
VAAEQVDVRSDVGMKTRKAGAVDAGKGRRGRRSAIREL
>SEQF2545_AGK84397.1 hypothetical protein TPFB_0749 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQDKALFSGALDTPFMQVITWARLYHKNQKRYEKIKKSFTFHETCLQSTKGIVAERILKPCVRRKVNGKFRST
>SEQF2545_AGK84398.1 von Willebrand factor type A domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHLKKALCPALCTFLIHLCLHAGERTVPVDIFLMIDKSRSMQEPGKFSSLHRWVRDEFVSSMTIQGDWITVYQFYEKPEE
LITLTLRSEQDRDKIISVVDSIVPNGRYTDIGRALDTVWEIQEKRKDNNRHKVLLLVTDLEHDAPLTSKYRGKQRSFQSP
YLVRARRVKHDNWYEITLDMAVHDRVAHTARELYRSIAAAHSKRPTPTPPAKESSPRYTPSLD
>SEQF2545_AGK84399.1 laminin-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNRPLLSVAGSLFVAAWALYIFSCFQHGHVPPRRIPPHDTFGALPTAALPSNARDTAAHPSDTADNTSGSSTTTDPRSHG
NAPPAPVGGAAQTHTQPPVQTAMRIALWNRATHGEQGALQHLLAGLWIQTEISPNSGDIHPLLFFDREHAEITFSRASVQ
EIFLVDSAHTHRKTVSFLTRNTAISSIRRRLEVTFESHEVIHVRAVEDVARLKIGSTSMWDGQYTRYHAGPASAPSP
>SEQF2545_AGK84400.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQFLSDTQRMVLSRAVCASFFFFHVAVAAYTARVQEMAMRGFALRNFQQVHAYFEQHIPLLSSFTEKKEALSLFAQYLEL
HDAHERAAHCYRDAALYALGTERVQFLLEATRNAMAADAREYARETLAEVEHIGVQVLNKKQHATFLVYHVWLALHAAST
AAHLHEQLERLEEYGTQGVFNVFETVLLFTRWWITQDEKVAQRLTERYPQSFEALSVIGAVEIAPSVFWHLMPRAYGEAV
ESMGKSETVVLQDAKLRPVPEVVAAHRTRRAHVAADGTAARSAMSSSHNLGVSILEGGVSVPDEVGAGDEKPRGYQLGFF
RAKENAQRLMDDLERRGFGFQLHTVRRADAVYYQVFVPEDDSGFVGHRLKDAGYETFPLF
>SEQF2545_AGK84401.1 hypothetical protein TPFB_0753 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTYGKLIFFIIVLVGFALFMSFNVEHRCDVSLVFYTFQAVPITLSLLFAFACGALTALLFLIDPDAKTRKQKREDSPTSA
PTGGVSSPEHVDVP
>SEQF2545_AGK84402.1 2-methylthioadenine synthetase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTYFFETYGCQMNVAESASVEQLLLARGWTKAVDAQTCDVLIINTCSVRITAETRVFGRLGLFSSLKKKRAFFIILMGCM
AQRLHDKIQQQFPRIDYVVGTFAHARFESIFQEIEQKLTQKDYRFEFISERYREHPVSGYRFFASSYSEGSFQSFIPIMN
GCNNFCSFCIVPYVRGREISRDLDAILQEVDVLSEKGVREITLLGQNVNSYRGRDREGNIVTFPQLLRHLVRRCEVKDQI
KWIRFVSSHPKDLSDDLIATIAQESRLCRLVHLPVQHGANGVLKRMRRSYTREQYLSLVGKLKASVPNVALSTDILIGFP
GETEEDFEQTLDLMREVEFDSAFMYHYNPREGTPAYDFPDRIPDATRIARLQRVIALQMSTTLKKMRARVGKTLPVLVES
RSRNNPEELFGHTELGEMTVLEGKVDPTYIGRFVDVQVKEVRGRTLRAHLVQERAK
>SEQF2545_AGK84403.1 PTS family fructose/mannitol (fru) porter component IIA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSEEILTIEEVARYLRISERTVYEWAQKGKIPSGKVGTVWRFRRSEVERWVDTCLSCSHRQSHSDVLPIERILSTDRILH
LEQSERRPALYELSDCLSTAPQIKNRSELAAEIVRREELMSTAIGCGIAVPHVRLSSVTDLVMAVGISKKGIADFGPLDG
QDVHLVFMIAAATNQHRYYLQTLSFFSSKLKRPDLRTRLLQTNTALEAYTVLTEQSSL
>SEQF2545_AGK84404.1 methionyl-tRNA formyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRVFFAGTPECAVPSLRRVACAHRVVGVLTNPPAAVGRSGKLVHSAVAREFFRLKASGVLPESASLFVPGRLDRAFYDA
VEALRPDVLVCFAYGKIFGPRFLALFPRGAINVHPSLLPRWRGSTPVPAAILAGDCETGVTLQYIGEEMDAGDILAQSRV
QLDGTETTGALLSRLSLVAADLVDDVLVGVERHTLAPAAQDHSQATFCGKLCREMGLADWSNPAVVLERKIRAFTPWPGL
FTYKDGERIAILQARSCESSFVPLAPVGTVLAADKNGVFVQTGDGVLSLLQLQRSGKKPLFWRDFLNGSPLLLTGRLGV
>SEQF2545_AGK84405.1 peptide deformylase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MELKFLGEPCLTTVSEPVSEVDEQLRAFISGMFRVMRGAGGVGLAAPQVGRTVRVFVVDVEHHVRAFINPQITAASEEQS
SYEEGCLSIPHIYERVLRPRRVSVQYLDENGKRCAVDADGILARVIQHEYDHLDGILFLDRIDEKRRDDALRRYAALRGT
IR
>SEQF2545_AGK84406.1 ribosomal protein S21 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAHITVDDSENLEKAIKRFKRQVEKEGIIREWKKKEFYEKPSTLLNRKKKALRRKLMKKGRKVSDSRLY
>SEQF2545_AGK84407.1 penicillin-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSAPTSFRVHPWDASLPCTGVHPSWEEARPAVNITRSRVAVFISSLTAVLLLLTVQCARYMLMRGNETKELNTLTERGAI
LDRNGRFLAVGTTVYNLSVNKNLVSDPRTAAHVLAQVLDLSEQDIEEKFRTARAHFFYLKKKMSETEKNLVAHALKEHSL
KGFRLEAVRNRIYPESSLASTVIGYVGDDGRGLSGIEYTLQDVLSPAPYHTGYTGKGHTVTLSIDRTIQYMMEKIADTTL
RRTQAEGLMFLAVEAKTGQILSYVSKPSANLSHFSQSTPAERFDRPALFIYEPGSVFKIFSIAALLELGVTYTHDTLHCD
GSFSFTSPFLKPGQKGHLIRCLRPHGTISAEDIIRLSCNDGMAQIAERADNHSFEQLLRAFGFGAKTEIELPGETVGLFS
PSERWSHRSKHTIAIGQEIGVSALQVVAAATALANEGVPLGLSLLHEVTTAEGTVVYRHKKKPKTRVISAVNAQKVLRYM
RTAAELGTGKKALVDGVPIAVKTGTAQMAHRNGRGYSDTDYLASCIGLFPAHDPEIILYIAIIRPIGQAYGELIAAPVIS
QAANEIIDYRGMVRANAPLIQHSGLIHTSERTPPRLGTHMPDLTGQPKRLLLDIAKRTDVHLVLTGEGYVYEQHPPAGTP
LTKGMTIELKLK
>SEQF2545_AGK84408.1 hypothetical protein TPFB_0761 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNSNSNKKRDPARFPAGVAQGCSTTRAGDLKHRRKHPFEKFFAQNSALFAQRFPDLARALTLPNEQLLQRIPPDYLLAAA
HDGDATLAVRGTYLHSKYRPRQEAARLISQDFFTHAIAKGGYVGAGLGLGYVAELYAQQHPTHTVVLIEPDIFVFLLFLA
SRPLTPLLRHERLKILPAQTVPDVLQFLRATGDVSLPLFHFLPAQELNTAWFHDFTQAHRHATAQAETNKQTLQRFGPLW
IRNTIKNAAQLCVRTPVNALRNCAAGSTALIIAGGPGVDASISFLPYLKKKH
>SEQF2545_AGK84409.1 hypothetical protein TPFB_0762 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRACARARVTPDVVLLFDPQYWNYLHVARAVAPHALLITDISVFPAVFRLPWEYIVLAGSACPFATSLAHHDASCSPSHA
LPLPFVAPDLLASGGSVATSAWECARYLGATTIVYIGLDLAFPGARTHFRGALFEERAHLQSGRVAPAETTSFCALHSLP
LYPVPAASDPHPGKNSPASPTGENKEQTVLTDARFSLYAVWLEAHLARYTHIKTYALEPAGRRVAGITPLRFSQLVTLLN
RSAAVPHCRTMYSRRRRLYSRYRNSSVQVNCTDAVRWRRTMKSTPVHCLGHFTKKKKSAEGARNLWRALRRADTRCASPH
NLEHALERTRSFLNAMPLTPTTYENKTHALYTALCTLLPTEPTYRARAHAHLFELLTRTLKFCAAYTEKEGEWREA
>SEQF2545_AGK84410.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKIKALVVLFNGALLLLCMGTGYVLFLTPVRGTGWQSVRAYGIFFLIFLLLFLLINTLYVKNRRLLRYLDAEDWSALAAL
LEEEVFTRNRVALRRVSLLSESLILLSDFEALERLEHFVHAQRPRYIMKCALTFAVGKLLAGKYSELRTFMTRVAATQAP
VQPWTRFYLAFACHLCGDFEQAHAHLLTLVHTKRQPLIRVLSAYLLSEVLPEKLRRAPAHDAQLIARGCAHAAQVRADVH
AHYTPRRWADYENRKKQNVDVLVFLKLMQDARAWLFP
>SEQF2545_AGK84411.1 HD-GYP domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNTYAIVDIPEETHFSDDVYLDDTFLVLTPAGLFDEALKSRLQEWDFTTVHTGGQLLSSETTLECPLPASGDPNAKGAPG
SEALRAQRSRFHALKKQYNEFQMFVEHVFDQYRAKQSLNTRAVIDRAKMLCELVKKHRQTLLRVLPTIPYREHYALETHA
LRSTLYAVVIGLQLKMQPFKIIELATSCLLHEIGMARVIPKAYTTEGELDPKTQKAIFAHPIISYHILRDHSLPLPVCVG
ALEHRERENGLGYPRRLVGEKISLYGKIIAVACSYEAATAPRSYKEMKNAAEGIVDLVRNANTQYDAVISRALLFALSFY
PIGTHVHLSNGKIAQVVDVNPDDPRFPIVQVHGEIHRNGKPIIHSTSADEIFITRALSVKEQRLILQEGGD
>SEQF2545_AGK84412.1 M41 family endopeptidase FtsH [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCFFAAPCIPPQRTSLSCAVRLSHSLSTFHLLFVYHGPACPRALQKGALTEMNTRYKQSDDSSDPFGFFKFSPRPQKGPS
SSRERPPRRNSRKVLSLVLLALCALLALANHFLFSRALRIIPFSEFKDRIASGEIVKVVVGSPYFVGYTSARPAPSARGF
SLLSEREAPTYHAIGVLSDSFLSMLDERQVVYSIKPRERNYLIETFQYLFPLLILFFVWRFFFKRMASNVSGLGSSIFSA
GHARSAAVEEGKVTTRFADVAGVDEAKEELMEVVDFLKFPKKYTEIGGKIPRGVLLVGPPGTGKTLLARAVAGEASVPFF
RISGSDFIEMFVGIGASRVRDLFKQAREKAPGIIFIDELDAIGKSRLNAIHSNDEREQTLNQLLVEMDGFDNTTGLILLA
ATNRPDVLDPALLRPGRFDRQVCVDRPDLKGREAILRIHAQNVKLAPEVDLKAVARITGGYSGADLANVVNEAALLAVRS
GRAQVIETDLDEAVEKTMIGLQKKSRVIREEERRIIAYHETGHALAGTFTKGADKVHKITIIPRGTSALGYTFHIPEDDR
HIVTEQQLLAEVDVLLSGRAAEFVAFGEVSTGAGNDISRATDIVRKMITDYGMSEKFQNVALTRRGTGYLAEPQLAREYS
ECTQQYVDEEVARVLAERYRAVVALLTEKKELLEYIATRLLERETIERDELEEVIRCEHDLEGLKKRLSQQQEGASAPAQ
GQSPPS
>SEQF2545_AGK84413.1 treponemal conversed hypothetical protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTPTYHPYPGDNRPFLYAALQRREHLSLIRYRAEHAQDLAPLRAFLARIEAHATVIGARTRGDTLFILAASMPSDALRDE
KHAYVRTISWEQAPQILETLERPPLPPYCPPVPTSCSSSRLIPDVPHNTRSHAQESSYTSRHALLTLLIEWRALMVEMDY
SVRAHRVRRSSAPLHERHGTLPSDVLLFQTQGEVCALCAFQLQHVRAVGGQRHLIIHEAAGGGNIACERIFSLKEIDFAT
AKFTERIRRGLYQVAVHTAHADFTVNLIVPSLREQGGAYSLAESSAFHRRVSA
>SEQF2545_AGK84414.1 hypothetical protein TPFB_0766a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRSERVVFPESMCALMPIFLKVEIPLLIAIPSSSGTGAQRNKPSGKRQGPAPQQTG
>SEQF2545_AGK84415.1 elongation factor EF2 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRGISTFRNIGISAHIDSGKTTLSERILFYCDRIHAIHEVRGKDGVGATMDNMELERERGITIQSASTQVQWKGHTINV
IDTPGHVDFTIEVERSLRVLDGAVLVLCSVAGVQSQSITVDRQLRRYHVPRISFINKCDRTGANPFKVCAQLREKLSLNA
HLMQLPIGLEDRLEGVIDLISLKALYFEGESGAHVREAPIPEQYQADVKKYRDELIDAASLFSDELAEAYLEGTETDQLI
RAAVRAGTIAEKFVPVFCGSAYKNKGIQPLLDAITYYLPDPTEVTNTALDLDRAEEPVTLSTDADAPVVALGFKLEDGKY
GQLTYVRVYQGTIKKGAELFNVRARKKFKVGRLVRMNSNQMEDISEGTPGDIVALFGVDCASGDTFCSGDLNYAMTSMFV
PEPVISLSITPKDKRSADQVSKALNRFTKEDPTFRSFVDPESNQTIIQGMGELHLDVYIERMRREYKCEVETGMPQVAYR
EAISARADFNYTHKKQTGGSGQFGRVAGFIEPIAGQDYEFVDQIKGGVIPNEFIPSCDKGFRTAVKKGTLIGFPIVGVRV
TINDGQSHPVDSSDMAFQAAAIGAFREAYNGAKPVVLEPIMRVSVEGPQEFQGSVFGLINQRRGVVVSSADDEQFSRVDA
EVPLSEMFGFSTVLRSSTQGKAEYSMEFAKYGKAPQGVTDSLIKEYQEKRKAEQR
>SEQF2545_AGK84416.1 treponemal membrane protein A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNAHTLVYSGVALACAAMLGSCASGAKEEAEKKAAEQRALLVESAHADRRLMEARIGAQESGADTQHSELFSQIQDVERQ
STDAKIEGDLKKAAGVASEAADKYEILRNRVEVADLQSKIQTHQLAQYDGDSANAAEESWKKALELYETDSAQCLQSTVE
ALESYRKVAHEGFGRLLPDMKARAGAAKTDVGGLKVAVELRPQLEEADSQYQEAREAEEVNARAKAFSGYHRALEIYTEL
GKVVRLKKTEAEKALQSAKTKQKASSDLARSADKSAPLPENAQGFSKEPIEVEPLPNDRLNTTQADESAPIPISDTSSPS
RVQSRGVEDGGRSPKSSMNEEGASR
>SEQF2545_AGK84417.1 treponemal membrane protein B [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKTRNFSLVSALYVLLGVPLFVSAASYDDNEFSRKSRAYSELAEKTYDAGEYDVSAEYARLAEDFAQKSSVYIKETMART
TAEDAMNAARTRHAWAKNERIDRAYPTEYLLASEAIKTGGLAFDSKQYDVALTWARKALDALKNVKPESQLLAKAAKEEA
ARKAAEARKLEEQRIAAQKAQEERKRAEEEAARKAAEARKLEEQRIAAQKAQEERKRAEEEAARKAAEEAARKAEELEKG
RVLPAQYKVTTWSIDRECFWNIAKNPAVYGNPFLWKKLYEANKDKIPQSKNPNWVEPETVLVIPSLKGEEREGLYEPNVK
YRPLP
>SEQF2545_AGK84418.1 putative ATP-dependent RNA helicase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQGAWLGAHRERAPRALERCGVQRSLCVFVSTRKFHFLLHFPSMGVSFEELGLNEQSLAAVRLKGFRCPTPIQAAAIPRL
LAGDANIIAKARTGTGKTAAFGLPLIQELGSPCEHPGALVLVPTRELAAQVASELSSLRIQKIPRIHTVYGGVSIAEQLR
NLEQGGEIIVGTTGRVIDHIERGSLELSYLRYFILDEADEMLNMGFVEDIESIFSHANKDARVLMFSATMPRQILSIAST
FMGSYEVVEEVTPEEARPLIEQFMWVVRDADKIEALVRLIDVSDNFYGLVFCQTKADADTVAKSLDERHYHVAALHGDIP
QSQREKILERFRTKRARILVATDVAARGIDIEGITHVVNYSIPHDSATYTHRVGRTGRAGSQGIAISFVRPHETRRMEYL
SKHCNGELKASTVPLVEHILTQKEGRIFSSLKTHLCQLLSEGVHGTFTRFAQRLLQEDLKARVAEALGTSADVPQEPNVS
LVAALLQIHYGTALDPRQYRDIKTITPETARARPHDAEKAYVRIEYGKKSYLTRKRVVQFICALVKIPGHLVDRVDITER
CAFARIPRRAAEEAVRLSKKRKDLPRVSFVGHASRLRNTATPAEKSTYPRRLPSGEGLREQISRRTSSSKKASGKPEDSL
PPPQEHRLD
>SEQF2545_AGK84419.1 PnaS family phosphate:sodium (Na+) symporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRRDYLRKERLTNKHTSVRRSVPLRTIDTYPLFLLWWAPMHLVAVLLQGIGSLGFMLFGMKLMSDGIQKGTGESLHKIL
QVMTSNCFFAVLTGMAVTAIVQSSGATTVMTISFINAGVLSLTQSIGVILGANIGTTVTAWIVALVGFQFKLASIAVPAF
GIGYFLTFFKHLHKGHLGESIMGFGLLFTGLGLLSSLIPPLSVEELSFLKIAVEDRALSVLVGLLSGFVLTVILHSSSAT
TAIVLTMAFGGVIGVEFAAASVLGSNVGSTIDAAIAAIGSKLNARRAAAVHVLFNVFGALVFLMFFHPVLALLYVLTPKN
SGFDNITVRLALFHSMFNIVNTIIVFPFTKHLAAFVEWLIRPRYDDAPERYQLVFQETAVKESAEAHIFRAEIELKKMFS
IAQGMLVTIRKSIQGTCVLSTDEIVTRLTKEEDYADQMQEQLSRFLIKTSHLSLSEKAKHNVQLMFSIADDIENITDHLC
GIGLYFHKSIKGNVPLKRDDIEELVPYVGMVDECVDFVYSHLNRPLEDKQVLHVNQMTHSIESKGAHLKGLVRRRLEQGA
DVKAELLYMDIVRGIEAVGNYALSISRWLARML
>SEQF2545_AGK84420.1 hypothetical protein TPFB_0772 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCATLRPMETLGFCMLSPSTLPLRKWGIRLCRAGYRALGALLGTGVLVCCASSTNMTVSNDYPPKELGVLNAYTVDRLRT
AISPRDFTFVFDPPIDTVLMQFKFLLDGITLYLERKDRTALREAIEKYLGEYEAQTLTREKSSERAYFGTTTPLMTWGIL
GSAHNATPTMRFEYQFITDDRPYFIIANRTIPGANGYNCPAVRIALSPAQCSQVMQYLDQGNLDALLEEMAQSFETFDTQ
QDPKKTPETDKNAAYKGKEKKGKKEERGPRSIMK
>SEQF2545_AGK84421.1 S1 family peptidase Do [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRIHHGSEVGLVRNKVRVLAVVAALAAACAVGFFLGRWFDFSARSSVLEAADSLSVSSSEAASFSTVVAEGDPYTVDER
QNIAVYRSANEAVVNITTEMVGVNWFLEPVPLEGGSGSGAIIDARGYVLTNTHVIEGASKIYLSLHDGSQYKATVVGVDR
ENDLAVLKFVSPPGARLTVIRFGSSRNLDVGQKVLAIGNPFGLARTLTVGVVSALARPIQNKGSIIRNMIQTDAAINPGN
SGGPLLDTQGRMIGINTVIYSTSGSSSGVGFAVPVDTAKRIVSELIRYGRVRRGKIDAELVQVNASIAHYAQLTVGKGLL
VSQVKRGSPAAQAGLRGGTTAVRYGLGRRAAVIYLGGDVITAIDNQPVANLSDYYSVLEDKKPDDEVRVTVLRGRRQHVV
AVRLTERSDE
>SEQF2545_AGK84422.1 putative MgtC family magnesium (Mg2+) transporter-C [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MITDSVIVVRLLLSFVSGLAIGLERSSKLQAAGLRTHTLICVGATGVMLLSLCVSEITGDHIGDPGRIAAQVVSGMGFLG
GGAILKMGANVKGLTTATTIWVTAGIGLVIGAGLYSAGAMLVLLVLITLAGLDKIEKCVFPTRQNKRLEIQFSHHEPEVN
EVMELLRKHSIIVISTNFQHSKSETSFPKLVLLISVPQKLNIRKLNHEVHMLECVQQFVLQETL
>SEQF2545_AGK84423.1 hypothetical protein TPFB_0774a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLSNRRIRVPVKRGSLKSARGHGVERREMNAQDSESFLKYELLDALKHMHLVVQFSDIKLLRYTDKQDELRKACLRLGML
KIG
>SEQF2545_AGK84424.1 DNA-(apurinic or apyrimidinic site) lyase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRLLDSKGVHAVFEQLHAANPQPQGELHWRNTFTLLVAVLLSAQATDKSVNKATAALFDVADTPQAMLALGEERLCSYIR
TINLYPTKARRIIALSAELIERFAAQVPCDAHALESLPGVGHKTANVVLNMGFGIPTIAVDTHILRTAPRIGLSSGRTPR
AVERDLLVVTPREFRMHAHHWILLHGRYTCTARRPRCTECCLRDLCCKNNI
>SEQF2545_AGK84425.1 hypothetical protein TPFB_0775a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRRQLVSELLLEIPENAAGRTAQQFFSYMLFLQHRSLRQHSVHRGLRAVQV
>SEQF2545_AGK84426.1 ComFC domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MILFSRARLWARDGVARAYVSFLGPRRCVFCASRCTGTVPLCCSCVQDRLYARAHDFLEHPEDFCSRCAKPLVSARALCV
SCRALRESGETPALWRVFSLLPYLGVGRPLMSLWKTQQERNFDALFSRIAGRFLRTARERSFVTASTELVPVPPRPCKMA
ERGWDQVEDVSRRLELAGFTVNRALVRVEGRFAQKTLSRAARVENLAGSIELGAHARVPRDALIIDDVVTTYATMDACAR
VLRSSGSERVQGFSFFFA
>SEQF2545_AGK84427.1 hypothetical protein TPFB_0777 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLKKRGLMKTLQCDICRKEVDNSLPERLYWTFREYDVCEDCKESIEDKLRPIIRTHQPYSQGWYENQFMGMVQRGVSNRR
P
>SEQF2545_AGK84428.1 putative nucleoside-triphosphate diphosphatase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMSTCAQAFYRLYEIIVRLRAPDGCAWDLAQTPVSMCSSFLEETYEALEAILEEGEAQHSSYAHVQEELGDVLMNVCMIA
YMYEQRGVFSLADVVTALTEKLIRRHPHVFGQTEGFPGPENPKRAQTAQEVFDQWERIKTQVERRRAASPLEGIPRTVPP
LMRASKMQKNASRARLFCPTRTEVVRECARTFRALRAMSENSAEQSATQAAHVAVGALLTAVISFAHLVGVDPVLALIRA
NADFVRRFSCACSIPAISGGTSVFLSRACHKPRRARTRASAVRRRARSRRLFFTRHKLGNMLR
>SEQF2545_AGK84429.1 membrane-associated protein DedA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVHTLFSWVSAHIHSLPMVVFVSLLLAGVHVPVSEDALIVMSALVCRQDGASVPSFLGALYAGALISDYAVYFWGYLLQQ
GALRVAALERTLASCRAQKIVTLLSRYGLWVYVLARFVPFGVRNVVSLTSGFVRVPFVRFACYDALAAACSISVLFWMTY
FLGSVQRISLKVFAVVILPLSVLGIRVLIGRRQKTTGDGVRITHDDVQTNVGVR
>SEQF2545_AGK84430.1 NAD(+) synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRGCGVDRTGGYVRLALAAPAVRVADCAYNTQRMIQTVRRAASCGVDILLFPRLSLTGCSCASLFAQDTLLSAVCTHVSA
LCAGTADCQLLALVSVPCFLRTQVRVCTALVARGRVLALVVQDTLAACGAQKMQVPCEVLYGGAPVPVYDVQTCFESAEG
LFSFCVGAMDGSVPATLVLQAYGTPSTAQTPDIFAAHAAAYSAQHQCAYAYVNAGWGESSADAVYGAESGIFECGQCVVQ
DSLQEMRERGERPAHAVRGLHVSADVDVSLVHFRHRARSGHTTLGASAPCVTLPAGIFAASKAHATLRRPRVPCPFFPPA
FQKSQDAVPPLTGAVCLAVSAPSDTQDGFLQRTIDLAAQGVALRLEHMGCRRLVVGVSGGVDSACALLICARALDFLSIA
RTQLYALTLPGFGTTSGTKGAAQEFARALGCTVQEISISAAVTHHLHDIGHTMQQCDGTYENAQARERTQILLDRANQLD
ALMIGTGDASEGALGWETFGGDHLSLYAVNASLPKTVVRALISYAGRVPERFVCETDSPYAPRGAAFSRVCAAIVAQPVS
PELIPPCDDRIVQCTEEMLGPYELHDFFLYHVTVNGFGPRKLFRVAAHAFGTAYSCAQLCAALRVFFTRLFSQQFKRSCV
PDGPGLTEVNLSPRVGFYFPSDTSGALWRAELEQLACGE
>SEQF2545_AGK84431.1 hypothetical protein TPFB_0781 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRTIFVGVLLLAIIGEGRLCALEWPVDKPKFLSLFGQSVGAGLLQQGLIFDGADSAGERGYAVRTAGYGRCVMRLQKHRR
ARVFPGALGNALIFAHEDGLQTVYANLREAKNAQDFGSTAEAESGVTVGYAGSSAWAPPNSFVFQVIDTKNKVYLNPLLL
LPSVSDTIKPTIQDVVLAGKTGVLALSGTAAPRDADGYVYTRKRTRVHRRVTQGTYRLYAAVADVLEHGTQTFTPFQVHV
VVNGSEVSAVSFELIVAKDSQACLSGSLLNERLLYEMKGRVFLGSVVLTRGTAELAISARDISGNERTEVFFLQVE
>SEQF2545_AGK84432.1 hypothetical protein TPFB_0783 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKEIARHCTFSPMKIKEKKGYFISFSALFLIAYMFVAAVPLGADPYFLPIWARDLASELHEERPERAVRVNADTVQTLQP
FMVGEYFGYFTDEGSVVFATRVTQRLSASTHAWAVYPEHAVRTPVFNPAGEHLAEIAEPGFVHIEADRFFLFSPGGNAVS
SYDARGVQRWRVLHTAPITAFHSSAAGAVIGFSDGKVMVVRADGTVRCAFYPGGSTYEIVFGVTLSADGTLAACVCGLDR
QRVILVSLADVQCKIVHHQYLEGALRHQLLMNFDTEGRYVVFEHAQGVGVIDCQRLETNIIPLVGDVVGMGVQPECDVVT
VLSQKEQRCRFAVFERAVHRVGDVRFDAQDVSLTQGEKKFFLSIDMLLARIDIAGIP
>SEQF2545_AGK84433.1 hypothetical protein TPFB_0783a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MARDLFQVRSPFLRGLLCFAAVGAGLLLLRCVLLSYLGRVVCPSFSARASVRLRPL
>SEQF2545_AGK84434.1 hypothetical protein TPFB_0783b [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVGVLRVAEGCCIQRKALLSAQQTRRRQETGAKRSRMRTIAPLRYNGRSRTDARAEKEGQTTRPK
>SEQF2545_AGK84435.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRIRLLFAPVSCLLLVCCADSSALRWIQQPSATRNTPTIAFFQVTFDRYNTHLLETRLHAQTLEFYHHDQTWTARDIHFT
RYDGNGRASVRGHAGVLLTDCEGTVFYLGKKVDCFFPHEGLRLEGRAFRWENTRALFTSDHFSPVRISDASGAVVTGVGL
CVNARTKRFVFQNGVHIDVDLDSFAKTRASRYAAPNLSP
>SEQF2545_AGK84436.1 OstA domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTRASSYPAFSPVPFLRTVLLALFLMSLCVWQRAHARGKVRFFADSLEGSADPHAPRTVLRGNARMYFADLEIHADKIEI
SGDDYHLVTATGNVRGEKKTQHLTFSAQSLHFSRNAHTTELLGAAQISDKRENVMARAERIVYHEKNETLLLQMNVSLTY
QDLQCQAMFGMYYRKSIFLELSGAPRVSDRGNLFQAERITLNMARREIQLHGKVQGSILKPYEWEQHR
>SEQF2545_AGK84437.1 ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAAALNKTFRTRHVVHDVSFSVHQAEIVGLFGPNGAGKSVSFSMVMGLCRPDSGRVLLDCTDITPLPIHVRARMGVSYVP
QEPSIFRKITVEANVRAIMQMRRDLSYTEQTERCEALLKAFQLTHVRNQRADTLSGGERKRVEIARALTVNPRFLIFDEP
FSGIDPCAVQDIKRIIVRLAHSGVGILITDHNVRETLQITDRAYIIHCGHIIAQGSPQEVVRSSHVRQVYLGSQFQL
>SEQF2545_AGK84438.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHCPLLRHTVVIEWAAPSMVGSAPVGRDSPAGMREAVYFLHRMVVCLGVLLCAASLLYVFGNFSHFLDKSQFIILRSCVG
CSVLLVVACLCAGSFELYFFLTRSDAPYGRLLCITVVALLFGMGALVFNTVVLIVAKGT
>SEQF2545_AGK84439.1 hypothetical protein TPFB_0788 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRVRTFCFSLVCALGASTYLLWRGWLQLSLPAGSYGVMRSRSGGYHHALIAPGRFLWRWEPLLPSNAELFAFELKKQTVS
VTVQDVLPAAKEYAQLLDQHAPFDWTLALSARVALKEAFLLDTVQRERITDQNSLERYVDTTAQAALTQVSHDFIARCMA
DPALYERVHTQYGLATRELKRAIEKEIPHCAISEVVLSEVHIPDMVLYHTAEQAYRAFEAKRSEHLSALAQQAAKRSALE
NFEMQRLTKWGEFFQRYPSVIDFLNAIRQDGASTLETLKKGSTASHRAIPHEETTR
>SEQF2545_AGK84440.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRIAYVPLCAVVGGMCSMWAQSATDVMGSFKKTAETGTMGTQARMVVRKAGKTVNTLVLKQYTRYEKSGEQKTLIEFLS
PLSVRGTRFLSLQKKDGAWEQYLYLPKLARVRSITGGDAHASFMGTDFSYHDLSLVGGVADLDECTLDGTESYGGKMCVR
IQTLSHKPQARYVRALLWIEQETGRFVKGEFFDKKDKRVKIMTLSDYETIQGVDTPKTVVLETIAQRSTTTIHLTKVEYH
MDIPEKVFTPEYLTQTDR
>SEQF2545_AGK84441.1 putative RND superfamily resistance-nodulation-cell division antibiotic:proton (H+) antiporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MWGRRMRCMKIPRQLTRRRLLERFYAHPWVLVAVLSALTLFFAVQLRTLRLDNNNFRFIPKENSVRIADQRIDSTFGSQV
PVLIGIKREYTSVVDPVFLADVRSLIERISAVPLVRAESTLSLLSAEYLGLRAGNIISERVVPDEFSGSAEEVQGVYRKL
RDWDFYERSLVSRDLRSMQIVVFLDTSNEESSSPEAMAACRAIIRILGAWKSRDAQTFVTGVTVFNEMGNEASTHDLTLL
VPLVVLIIIVALFVSFRRLAGIFLPLLTVVISTVWALGAMALCAIPLSILSAILPVILIAVGSAYGIHIVSAYFYGASSR
ICSTRQEHRARIVEAVDKIIQPVFLSALTTFVGFVSFCFTSVVPIFEFGVFASVGVASAFAVALMLIPSLLIIRGPESRV
CAHAPDAGHEHMDTAITGTLMVIAHHYRTVLFVAFLAVVFSLVGMSRLVIDNVLTEYFEPEVTVVQSDRFMQQHFGGSRS
LTVLVSTPARDGSVARPDVLKAMDDLTEFLQTRVEHVGKVISLVPLIKRINQVYNADASARGLEAQSADVVRGGTDDFGV
FKTFTGGHEEPARAETSRTSLAAPGSSYDFRQAVGMLVSAVRDSDFDRSDAQQLVQALEKAVNYDGRAYYEIPCDPKKYG
VKTSEELQEIISGYLLLLSGKGLGLVDRAVDPRALKMNIQLGTKGQQDSYGVIEAVKKFIRENFPQDVHAEFGGSVLVEQ
SLNDLVVQSQLISLVFSLCVVFIIIAVHYRSLFAGIIGTLPLGVSVLVNFGVMGFFGIKLNICTTMVAGFSSGIGVDYTI
HYLAAYRRAWKECGGKDFLTQTFYGSGRAILFNVLSVGSGFAVLMLSKFNVLADFGLLMVLAMLTSSVASLTLLPTLLNV
VKPRFITR
>SEQF2545_AGK84442.1 hypothetical protein TPFB_0791 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MREHSAHVVIDDHEALLLLVLSSGPAALASLPLHPVLGKGYRNTPGALEEKAVRISCVRECLNVVQIGGRIPVLLTSAAE
LPRLGSCVR
>SEQF2545_AGK84443.1 flagellar filament core protein FlaB [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIINHNMSAMFSQRTLGHTNLSVQKNIEKLSSGLRINRSGDDASGLAVSEKMRSQIRGLNQASTNAQNGISFIQVAEAFL
QETTDVIQRIRELSVQAANGIYSAEDRLYIQVEVSQLVAEVDRIASHAQFNGMNMLTGRFARQGGENTVTASMWFHIGAN
MDQRTRAYIGTMTAVAMGIRDAGDESVMNIDSPEKANRAIGTLDQAIKRINKQRADLGAYQNRLDHTVAGINVAAENLQA
AESRIRDVDMAKEMVDYTKNQILVQSGTAMLAQANQATQSVLSLLR
>SEQF2545_AGK84444.1 hypothetical protein TPFB_0793 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRTLTELDKKVLRAEFPQLSFSEDADIDRYFELRSLGDQRQALDIYNRTLLVKYPQKERRVLLMSYYRKRDVRFKEVLAD
ALAELAQKKIQEIKKIIDFFAAAVAPLDLTDVRTLIRVCEKIVRSISLNRFESVHFSRKHTHYAQWLLYREKEMEKAADI
IRMYVTDTLSSVRTFRQESHTRATYGFCTEAHGTDTSSTIDFSQLVFTAEQVRTIEIAKTITKIEDRVLAYAIKYWHRYD
DRAFENTVLLYSRKYKTHHYNIFHSIKTGRSHQWKDEDILHLVLAHVASGYYYSISGDLYLQRNWHWLKARLVERAEHHH
QKGKKVPATHRRSSTPHARKTAGTRARTRARKKELPALPSEKISKKDSGESKQKDETAGMERVFRHNTKNVRTCSSRASR
TGTHAEARHSDIVTSSPVHQEGAATVERSSPPEETVESIAHIVKRITGKDYGVYRELFFKEVRTAIRTVLNRATVRRGLR
LRARKNNAEDTIYHFLHTHYDDPYQRWPNSHEYQQVHTLGFSIHSLEPIIVTWAESEGL
>SEQF2545_AGK84445.1 methionine adenosyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
METFFTSESVSEGHPDKLCDQISDAVLDACLSQDPHSCVACETFASTSLILIGGEISTRAHINLTQIARDVAADIGYVSA
DVGLDAASMAVLDMTHHQSPDIAQGVHGAGLKEFAGSQGAGDQGIMFGFACRETPEFMPAPLMCAHAVVRYAATLRHERR
VPWLRPDAKSQVTVQYEGHRPVRISAVVFSQQHDPSPSYETIRETLIEEIVRPALAPTGLLDENTRFFINPTGRFVIGGP
FGDTGLTGRKIIVDTYGGMGRHGGGSFSGKDASKVDRSAAYMARYIAKNIVAADLAERCEVQLAYAIGVPYPVSLRIETF
GTARASESHITHAVKEIFDLTPAGIVRTLDLCAPRYRSTAVYGHFGREQFPWERTDCVCDLQRAVRPFALSGQIKE
>SEQF2545_AGK84446.1 hypothetical protein TPFB_0795 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHSTPLVSAALIFAYTLTSDRTPAHASCTHTMMRTVRHTFLHTNSTRAVLTL
>SEQF2545_AGK84447.1 putative ApbE family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKSSCVYWRIGVLVCILCGVGSCGGRARVREYSRAELVIGTLCRVRVYSKRPAAEVHAALEEVFTLLQQQEMVLSANRDD
SALAALNAQAGSAPVVVDRSLYALLERALFFAEKSGGAFNPALGAVVKLWNIGFDRAAVPDPDALKEALTRCDFRQVHLR
AGVSVGAPHTVQLAQAGMQLDLGAIAKGFLADKIVQLLTAHALDSALVDLGGNIFALGLKYGDVRSAAAQRLEWNVGIRD
PHGTGQKPALVVSVRDCSVVTSGAYERFFERDGVRYHHIIDPVTGFPAHTDVDSVSIFAPRSTDADALATACFVLGYEKS
CALLREFPGVDALFIFPDKRVRASAGIVDRVRVLDARFVLER
>SEQF2545_AGK84448.1 pyrroline-5-carboxylate reductase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNVGFLGFGAMGRALAEGLVHAGALQAAQVYACALNQEKLRAQCTSLGIGACASVQELVQKSEWIFLAVKPSQISTVLRD
RQSFQGKVLISLAAGMSCAAYEALFAADPHQGIRHLSLLPNLPCQVARGVIIAEARHTLHHDEHAALLAVLRTVAQVEVV
DTAYFAIAGVIAGCAPAFAAQFIEALADAGVRYGLARDQAYRLAAHMLEGTAALIQHSGVHPAQLKDRVCSPAGSTIRGV
LALEEQGLRRAVIHAVRAALSSS
>SEQF2545_AGK84449.1 methionine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTRKLITAALPYVNNVPHLGNLIQGLSADVFARFCRMRGYHTCFVCGTDEYGTASETRAAEQGLSPAQLCAHYHALHRDI
YQWFDLSFDYFGRTTSDAHTELTQALFRHLDARGFISEHESAQAYCLHCARFLADRYLRGTCPHCRNAEARADQCEHCGV
LLEPETLLNARCVSCGTAPEFRPTRHLYLNLPALEKAYRSWFCTTNHLWTKNAVRMTEGWLRTGLQERAITRDLRWGVPV
PKAGFEQKVFYVWFDAPVGYISITKCGTEAASSQEGGGTDDGVKEKWQSWWLDQQDVELVQFVGKDNIPFHTLFFPCMLI
GSGQRWTMLTRLSATEYLNYEGGKFSKSLGVGVFGSDAKESGIPSDLWRFYLLYHRPEKSDAHFTWHEFQERVNSELIGN
LCNLVNRTLTFVARTYGGVVPAQDGARSTRAQVMEETLALREAVRNTAKRMTDLMEQVQLREAFREVFALSARANKALQD
GAPWKTRAQDRERADALMRELCYVIRDVLILAHPFLPWYTQQAARFLGVQLSSCAPEGGGAVCAAKKDADTAQPDTVQPT
LRWSDVGERKGLTQVHPPVILFRPLETETIAAYRARYAGTARDGAGVSVPRTAQMPTGMNKKETDAQQKKEEREMPPPSD
TARLSAFFSERVVLKVARVLQVERHPNADMLFVETLDDGSGVERVIVSGLVPYMAADALRGAHVLIVDNLQPRSLRGVRS
CGMLLAAEYVDAQGTKAIELVQAPWALPGERATLASAPPVITPHGSAVIDADAFFSVPIRVVNYAVEVAGEPLMVGGRPL
VMQRVKEGTVG
>SEQF2545_AGK84450.1 hypothetical protein TPFB_0798a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRSVQRRIHQSCCVLFFFVRHILHRMLLASACPFGQHLLPETCLHEVLFKSE
>SEQF2545_AGK84451.1 hypothetical protein TPFB_0798b [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSGLSNGQYTRVPGVPAHRIRDRAYGTGRPHVRHPLKSTPRHVLCITENTTRVIIQPPGRACCLHYFSIAECEVCSEGFI
NPVAFSSFL
>SEQF2545_AGK84452.1 serine-type D-Ala-D-Ala carboxypeptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPGHPVHACTARLKDHSSRSLRAVARRRGQRALYALGACVVGAGALQWHAQRVLHPSFLFSPTLRFSPSSRNPFSAHPIR
TLQFTNLSAGSTPPPISARAYAIAEGGSGTLLASFCADLPLPPASLAKLVTCAVVMEALERGELHWQQRIRVPLAGSAQA
FAPGSSLIFLRTGEYISVHDLLAGMNIASGNDAAYTLAYAVAGSIPAFCTRMNTLVQKWGLTRTRFVEPSGLSEHNVTTA
RDFVLFCCQYVRRWPENLARFHARSYFQRSNSPATSRIPPHTRFPATNTLLAATAARGNVSTAVPGCDGLKTGYIRESGF
NVALSSLRGDTRIIAVILGGAGNSIPEGKRIRARDGATLLYWAFTHFQCTDVRTAISDALPRAIPVLGSKRPGALRPILH
PSCTSCPVLNTPGTRISITFALPPLLRAPLQETDVIGFAHVLDESNGMVLARVPLVSGTTLTAGGNARRIIDEVAVWSVE
LWRKIREKRV
>SEQF2545_AGK84453.1 S14 family endopeptidase ClpA [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKIIISASVQIILDQAFDLARKRRHEYITAEHVLFSALAHPAALEIINLCSADIALIHSNLSEFLKTQVPVDLSHTPSQS
LGFQHLLKRAVLYCEANKKSALEVGDLLVSLLQAETNYASYYMRMSGMSTARLIEVIARVNGIRHGDKNVSMGSNAQERY
SESDDVGESAGHGPPLDGTEGDGNTADVHVHYEHCAHKRTDADTHRYTVLEKYTVNLTERARRGELAPLIGRTQEIERTI
QILCRRQKNNPVHVGEAGVGKTAITEGLAQRIVRCDVPEALEGVEIFSLDMTSLLAGTKFRGDFEERLKRLAEELEKKTQ
AILFIDEIHTVVGTGSGGSGGLDASNLLKPLLSSGKIRCIGSTTYEEYTKHFRKDQALARRFQKIDIEEPSEEETLRILE
GIRTLYEDFHAVHYSDEALAAAVRLSVQYIQGRHLPDKAIDIIDEAGACAKLSRGKHGTEGVCSVIGESDIDEIVAKIAK
IPKQRVSASEIEKLRNFERSISEKIFGQGEAIDLVTRTLKRARVGLRVKHKPIANLLFVGATGVGKTELARTLAQELGIV
LHRFDMSEYQEKHTVSRLIGSPPGYVGFEEGGLLTDAVRKQPHAVLLLDEIEKAHPDIFNVLLQVMDYATLTDNQGRKAD
FRNVILIMTSNAGARNMGVSLIGFHKGQVGTAVIDEAVERIFSPEFRNRLDAVIRFDALSLETMERIARKELALVCEQLQ
KKHIRFDITDDALALLAERSHSGGSGARNVARLVEQEVANVLADLMLFGGVAEGDALRCTVKDRHAQCNFLRIECVQSSY
SGSIQDALG
>SEQF2545_AGK84454.1 hypothetical protein TPFB_0802 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHRSTDDNFHFLSIPSWGMPPCVRFLQHAPTQSQDTPCTRQGCSPFIYARRAGTPLRAARTAKTMQPRETSSCKRKTQYN
LGSVTSGAHTITPAHAKLPLAQRYCKFTRVTREQHYPENNWENGLICRTPADTL
>SEQF2545_AGK84455.1 hypothetical protein TPFB_0803 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGALACDYTYSPSPKRDLSIAAKNAVVRNILQEIAIHGSFLLLGHEHPDEDCIASLVAFALLLTRCNKRVEICCQGPIRV
QISFLIDICLYNGIAVHLDTQTVPRMPDALVILDTPNPGMIYAPPSCRLLLSDSTIRKIELDHHLFANAACCGDPGYSLI
ARASSTCEIIAYLCYKLARNHAQRTALGIRNLYSRNVVLSILTGMIGDAKTGAYLISRKDRALYTYFTQRLNTMLREKTK
PITGNIASTKQILHTLESLSAEEHAVYQTMVKNVQHRGSISLLLLNQTQTQALHECCNAEHFVSLIKMATSNIAESISGI
GISAYPDPTQQFYVTQWRVRTAARVKQLDLRLLLSHFAIQNGGGHAGAIGFRFFAHELINQDLFTEALVAYLDDRLHHMQ
SA
>SEQF2545_AGK84456.1 sugar ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKVELKHICKTYHGCVHAVKDVTITVESGEFVVFIGPSGCGKSTALRIIAGLEDICSGDLYIDGEHMNHVTPKDRNIAM
VFQNYALYPHMNVFDNMAFGLRIRKIPQQEIIRRVHEAARVLDIEPLLARKPKALSGGQRQRVAVGRAIVRNPKVFLFDE
PLSNLDAKLRVQMRSEISLLHKRLKATMIYVTHDQMEAMTMADKIVIMKDGCVQQIGSPLHIYQHPANTFVAQFIGSPPM
NCFPVTIVKDEHGIKIDAGLFVLRPDIPASFLLKNYIGTQVVFGLRPEAITPRTEETLARECANVIQLKVLAVEALGAET
FVYLDAGVQPIVARCNHTLTAHEGTLLTLALDLSKALYFDAETGHALQGGTSQVATVHAPPEISTGE
>SEQF2545_AGK84457.1 putative exoribonuclease II [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MELHVGSPVLYRKRPACVHAIERGKDAKITIETEHGLRRVRVKDVLLLHPGTVSSLVELLSASHIARISEESVQDAREFF
GTEAPSFFELAELLWGASAAQSWAYWEQSVQSAYFVCNEPAAAVRIRSQQECASCAVQEEKKEARQALKQAFIQELRRVA
RSARNMAPTAQEGMHRVHVSQVNEQFTPFLQEIEAFALGHANRCKILQCALGCEHREQAHEILLHFGFWPVYRNPYPDRL
CPLFLSPAHVSGSDGERAAQQDVHTHRCVTQARTDCTHLAAYAIDGEGTRDPDDAISFDGTYFWIHVASPAELVLPDSHA
DACARTRGASLYLPEGAVRMLSDVVVDTCALARDAVSPALSFKILLDEHGDISCVHVLRSMVRVTRLSYAEADSQRDTPA
LQPLFDFARNNIARRKGRGAVDICFPDVHMRVDFPVQETGQAGKEMNAGDVPDTQGKVPRVHIEAQQSYESMSMVREFML
LAGEAAARFAFLHNLAFPYVSQERPQLPVQLPAGLAGEYKKRRAMKARRVSTTAAVHAALGLSQYSQVTSPLRRYVDLLA
HQQLLACIDHAYAKAPAVGSAQTNETLALKLAQADEAARQATQAERVSRRHWTLVYFLMHPHTRYEAIVLEPLQPRAHVW
LPAVALEADVALGRQAQFNERVMLRVVRVRLATLEVHFSVCEHCHHGVTQAVEGEAEQPS
>SEQF2545_AGK84458.1 FemAB family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPPACVGVRDGCIARGRERIPLHTERTGSARQVMELFGRYLDPVHGEQYNGCPMFVVTVQKWTQETWTAETFLQSPAWAH
FKRAYGWQTYVFSVHVRPDANTGGEKHFPLLILCKNIKPFGVFAYAPGAPPYLQDDQIPSRQMARARASLLRELTSALLP
FFVRKPFLVRFDPPWGWAAAVCSLPSLASSSTHCAVGTEMELFTRELHACGLRRAACNVQPQDTLLLDMRPAREDIFAAF
KPKWRYNVRRAQKHGVRVARFDTLAQEGSPGSLRAAVDVFYALYQKTAARDRIAIHTRQYYRDFCTAFAAQGMLVLCLAY
APRAALRVRIAGKDTPKNIETPHPPASEDRELGCADEQAIAALVLLCFDTCATYVYGASDYSARHLMAPYALQWYAIQEA
RARGCLWYDFYGIPPTDDVRHPMHGLYRFKTGFGGFVFHRVGSVDMPVRQLHAAAYACAERVRMGWFKRVRRMVCACLQS
LGRQRTQNYSAHTAGAGA
>SEQF2545_AGK84459.1 ribosomal protein L32 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVPRANTSKARTRRRRAVNMRLEAPHLVECGNCGNFVQSHRVCGRCGFYRGRQVINPDDLC
>SEQF2545_AGK84460.1 acyl carrier protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDELFLRMRALVAEKLEVEEASITLDSSFRGDLGADSLDTYELVYAIEEEMGITIPDEKANEFETVRDAYEFIKSKVT
>SEQF2545_AGK84461.1 ribonuclease III [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSLCLGHIFSRSRSPLTPERRESLRRLQETLGVKFRDPTALDQALSHRSLFSSKEDHCGVRHNERMEFLGDAVLGAVAAA
CLYRALPDSHEGDLAKTKAVLVSTDTLSDIALSLRIDHYLLLGKGEELSGGRHKKAILADATEAVIGALFLDSGFKAAER
FVLRLLLPRVRPIREKNLHHDYKSTLQVLAHQRYRSKPEYTVVKRTGPDHSVRFWVDVTVGDARFGPGYGTSKKSAEQCA
ARLAWEQLSGTLRE
>SEQF2545_AGK84462.1 site-specific DNA-methyltransferase (adenine-specific) [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRSDTARPFVKWAGGKRALAPTLFAHMPQTFGSYFEPFVGGGALFWHLCACTRVRLHDIYLSDINWPLLCAYAAVRDRV
EELIVRVGQHIACHTPTYYRLARRKFAVCEHPLEVAALFLYLNRSCYNGLYRVNKAGQFNVPLGRAAPASPFLNTTAPTP
RSTQPAAQVGHLAIRIDEENLRSCARALANTTLNCQHFSCIQPARGDFVYLDPPYLGTFSAYDKTGFDRAAHESLAAFCM
HLDARGVLFMLSNSDCPEVRAWYRPFRVQQLNAPRCIARSAHARGKRCEVLITNYPCADTATP
>SEQF2545_AGK84463.1 hypothetical protein TPFB_0813 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGAATTGFPIKAAVIHFTALSRHEQYIVSRALCALRTQPRRAQVVRRRVSNLKRLVRAMRSYSGADGADVERFGKGTVTD
LADAGRFLFLPARVALRRGYLIAKIQTFAFLTQEVTRVALAEYLVQELRQVQFALVCMLMTEDLYLSLMEQEHVPARLKT
AVTHALVALWEQRPDERARRATSALHQVWCAREHLAPSFGSMLGSSELFLLSTELDEMWRDFLVQRLSEAGVCTALEEFL
FGISHEQIQAIRLQLRAQGVAALSRQEAYALIGEKGGGENTQAHAYQRVADLCSFYRSFVIRKRDAQARLRLNMPGPVRT
IEEHYVEYLFFRQGEACFVH
>SEQF2545_AGK84464.1 thioredoxin-disulfide reductase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
METDYDVIIVGAGAAGLSAAQYACRANLRTLVIESKAHGGQALLIDSLENYPGYATPISGFEYAENMKKQAVAFGAQIAY
EEVTTIGKRDSVFHITTGTGAYTAMSVILATGAEHRKMGIPGESEFLGRGVSYCATCDGPFFRNKHVVVIGGGDAACDES
LVLSRLTDRVTMIHRRDTLRAQKAIAERTLKNPHIAVQWNTTLEAVRGETKVSSVLLKDVKTGETRELACDAVFFFIGMV
PITGLLPDAEKDSTGYIVTDDEMRTSVEGIFAAGDVRAKSFRQVITATSDGALAAHAAASYIDTLQN
>SEQF2545_AGK84465.1 hypothetical protein TPFB_0814a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCVFYPSRGGYCSLSPSPTLSEEALELALAATVCLLQKGLAGSCAGVHSIFQEPLGPCTLSVSSVPPSWGT
>SEQF2545_AGK84466.1 hypothetical protein TPFB_0814b [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRVEVANETRHYVPHDGGTEETESVHGPRGSWKIECTPAHDPARPFCKRHTVAASASSKASSERVGDGEREQYPPLEG
>SEQF2545_AGK84467.1 putative GNAT family acetyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSFAKGSGGVVRRCALDLPGASRAMHAFCLLCTSVVGDIVSRLVRNLDAHTIDEALAFVKSREAFSVSLAEYLKAAKCSF
STRGTAPFIRGGSVLYRDAEPCAVLLLTRAGLLLHNSEPNTNSAAIYRACKRLVTAQVRSIVGTEMHTCVIARSISGITT
HAQQERYYLLVLPLHTPRVEYEQNSAPLHIRRAQLKDMRELFPLHMHYKREEVLPVGNSPKHKATVRTLHAHLRTRVIFH
ASIGGHIVAKAQTNAHGFHCHQIGGVYTVPAYRNRGIATALVATLAYNRLDIGKTPVLFVKVRNMAARRVYEKIGFTLHG
LYRVINL
>SEQF2545_AGK84468.1 hypothetical protein TPFB_0816 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCFILPRMGAGVFVSDNRLQFSRSLAEVLRNQGCRVCLSAHEAARGDVPVRDGLVYWNRASPFSLRGILLQIENLGIVLE
TAVFVFDAQSYVDLYPGDDFSSIDRISVDLIVANMALVHMLTAHFVSQARGKLLFVHRETSAHCASAMVSVASAAFVRMA
EECVLGLARKDAPRMQTLLIRLDGVDDDSYTQWIATQLASPVLSRGPGRWVRAGQRSFFGK
>SEQF2545_AGK84469.1 phosphopyruvate hydratase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSDIACIEAREIIDSRGNPTVEVDVSLSDGSFGRACVPSGASTGEFEALEMRDGDKERYNGKGVLKAVGTVNTLIADTLE
GMDALNQGEIDHAMRNLDGTDNKSKLGANAMLGVSMACARAAADFLGVPLYRYLGGVHTFRMPVPMANIINGGKHSDNKI
DFQEFMVMPIGAASMREAVRMTAEVFHALKGLLAADGKATSVGDEGGFAPDLDNEQALEYIMKAIAKAGLAPRKDVCIAL
DCASSELFDEGDRRGYKFWKSNPGKLFTAQEMIDLYKKWIATYPIVSIEDPLDQNDWAGYVQLTKELGDKVQIVGDDFFV
TNTGRLARGIKEGSCNSILIKLNQIGTVTDTVDAVRMAQNAGYAAVISHRSGETEDAFIADLAVALETGQIKTGSMSRSD
RVAKYNQLMRIEEELGAQARYYGAKTFERFGC
>SEQF2545_AGK84470.1 hypothetical protein TPFB_0818 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEYRGGWYSYFLCGVLSGKGARRAGAIERVENLYAFFFACYHAPTSGGLK
>SEQF2545_AGK84471.1 ribonuclease Z [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNLEAFILGCGGMVPLPHRHLTSVLLRREGELFLFDAGEGTQVSLRRLSLRWKKISAIFISHTHADHITGLPGLLMLSSQ
VARSEPLYIIGPPRTAEYVETSRRILDMYINYEIIVKEVIEPQVVYRGKDFQVRCFCLDHTKPCMGYTLEEQDRPGSFDP
RAAQDLHVPCGALWSQLQSGVAVQSAQGVTVYPEQVMGPARPGRKVSFVTDTKYLQSIAAEVRNSDFFVCEGMFEKGMEK
DAAEKKHMTCVQAATIARDARVRLMALIHYSPRYTDHELKRLLKEAQRVFPHTILSRDQLMVPIAYRE
>SEQF2545_AGK84472.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRVRVAFHKGRALCAGAFDVSEGGAVFTRTRTVAGAFVLVWFLARGSAQEQPPAAAQAGAAEVREALSLYRNGRSMDTS
GRREDAQKMYTQAVELCRSVLERDPRHADAYAVCTWSLFRLGRYADTVALCQEALKISVDHRVVETLAEALFFVGDYKGS
MHAMERYIDMAPRGERISVAYFYLGEIFRLTKRFRKADIAYSTAVNFEPSNALWWYRLGLAREYAGDKGFALDAYRRALH
LRPEYKEAQESIRRLS
>SEQF2545_AGK84473.1 putative metal ion ABC superfamily ATP binding cassette transporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKGKTVSAALVGKLIALSVGVVACTQVKDETVGVGVLSEPHARLLEIAKEEVKKQHIELRIVEFTNYVALNEAVMRGDIL
MNFFQHVPHMQQFNQEHNGDLVSVGNVHVEPLALYSRTYRHVSDFPAGAVIAIPNDSSNEARALRLLEAAGFIRMRAGSG
LFATVEDVQQNVRNVVLQEVESALLPRVFDQVDGAVINGNYAIMAGLSARRDGLAVEPDASAYANVLVVKRGNEADARVQ
AVLRALCGGRVRTYLKERYKGGEVAPAL
>SEQF2545_AGK84474.1 MscS family small conductance mechanosenstive ion channel [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVSRRAQAGNMRELEHFVQSLATAACALGAGLTQVATSERVWYLLRFVAVLCITSAFFRMLRRGVRRVVARRLSAQTQHF
VFKTLNYLSFTVMTFTAFHWLGINVSALLGAAGIAGVALGFAAQTSVSNVISGLFVMTERAFRIQDVIEIDGIVGAVQSI
NLLSVALKTLDGQYVRVPNETILKANLVNYSHCPHRRVKTEVSVAYGSDLRRVQQLLLDVATRNRFVLSDPAPAVLWNAF
ADSGIDVTLLTWTHIEHFNDLRNAIFVDIDECFKQAGIEVPFPHVDVRVQGACDAPRAETV
>SEQF2545_AGK84475.1 putative superoxide reductase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRELSFFLQKESAGFFLGMDAPAGSSVACGSEVLRAVPVGTVDAAKEKHIPVVEVHGHEVKVKVGSVAHPMTPEHYIAW
VCLKTRKGIQLKELPVDGAPEVTFALTADDQVLEAYEFCNLHGVWSGK
>SEQF2545_AGK84476.1 hypothetical protein TPFB_0823a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGTGKDAVECDGELDDTEVTGKMTTIGTDNAQDLLAYLLRERAHLLGGETLKIVGPSEGAKQRQIHDENASCRTEGARAE
TTCSCADSCEASSCACGLLSFAFFFSFRRARRNSSGIQAGRSVAETTQMVKVYSCVAQARKERVY
>SEQF2545_AGK84477.1 1-deoxy-D-xylulose-5-phosphate synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDLSLLRSLTGPHDLKSLSPEQVRALAQEVRQEILRVVSANGGHLASNLGVVELTIALHRVFSCPHDVVVWDVGHQCYAH
KLLTGRAGRFHTLRQKDGISGFPRRDESPYDAFGTGHSSTALSAASGILSALRYRGKSGKVVAVVGDGALTAGLAFEALL
NVGRSCSDLIVILNDNKMSISPNTGSFSRYLSTLTVKGPYQKLKTRLRRALQTVPLVGRPACRALSRLKRSARTLLYQSN
IFADFGFEYVGPLNGHHIEDLERVLNDAKKLTRPTLLHVQTVKGKGYPFAEQNPTDFHGVGPFNLAEGIVEKKDALTFTE
AFSHTLLNAARTDDRVVAITAAMTGGTGLGLFSHIYPERFFDVGIAEQHAVTFAAGLACAGVKPVVAVYSTFLQRAVDQV
IHDVAVQNLPVIFALDRAGAVPHDGETHQGLFDLSILRAVPNINILCPASAHELSLLFGWALAQDTPVAIRYPKALCPPE
EDGFSTPVHTGRGVLITRENECNVLLVCTGGVFPEVTAAANTLARKGIFADIYNVRFVKPVDEDYFLDLVGRYRSVLFVE
DGVKIGGIAEALQALLNTRHPAPCSDVLAFQDMFYPHGSRAQVLAAAGLSAPHIAARAEWLLAHSVGQIR
>SEQF2545_AGK84478.1 hypothetical protein TPFB_0825 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAVSPFSWADSVNSMHLHAVRYIRVRLQRMRQMAAIQRKERGGPACSRQAPGDRIRFNRRTRCLESEHRAIS
>SEQF2545_AGK84479.1 hypothetical protein TPFB_0826 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLFLRSMVLWYAAYVRPLLDVALLSFLLYKTYEILVKTQAVQLVKGAFSILVLYALVFVLKLETLLWILNATAPGVAISI
TIVFQPELRKIFLKIGEKNWLRQRECAHHTHIDAVLTAADVLSKRKRGMLVVFARHHTVREVSETGTALYARLSSSLLVT
IFGHDTPMHDGAVIVRDGLVVSAGSFLPLSEQHDIRKTFGTRHRAALGMAEKTDAITLVVSEETGALSLAYDSKLYYDLP
HADVLAQLKQLLETTTRAGHAQGTLDHGRSTLS
>SEQF2545_AGK84480.1 hypothetical protein TPFB_0827 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVAARCLDRIAHNWAAKASSILLAFLLVQFYSGSLLERRAISVPLVVRNEGALTPALRFPQKVTVLMRASRDTLGALRGS
DIVPYVDLSSYTEEGEYAVPVRVTVADHVAPPDALELVADPAIIPFKLERSVTKNIPITLSLEGVPAYGYELREVDTNPS
MVEIRGPASLLVSYTQAVTETLDITNRRASFSGVIGLINPSTLVSFPKTKTQFVVRVREVSELKELETTHVSFTDCAPHL
TFSIEPVTIRAQVQVPKHVIEEMHPEEFFSVSAREITEPGRVTAPLILSLPEHVRMVQYSPKEVHVHVREAQSVPADGHE
>SEQF2545_AGK84481.1 holo-[acyl-carrier-protein] synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIIGVGIDIVEIERFVSWTHNVRLLRRFFHQEEIVDFFKNHMRAQFLATRFAAKEAFGKALGTGLRNMELRNIRVCQNGW
GKPRLEVYGAAQAMLAATGGTHIQVSLTHEREVASAIVIIEGEPL
>SEQF2545_AGK84482.1 hypothetical protein TPFB_0829 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTRSSTKKTDKKESTVSFYSKERIECPVCTTVFQREEMHSGGGRTIAGDLTDELRRTYETSAKYGEVFPPIYHVVVCPTC
LYATFLQDFRNIERGIVTKLSSTTSQRRTSVERLIPQVDFSALRTLSSGAAAYYLAILCYDFFDKKYSPTIKQGICALRA
AWLFSDLEKKDPNEHYDYIRNLLYQKALFFYRKAIECESTGEEIIAGLKSFGPDTDKNYGYDGVLYLSYLLEYKYGTKRD
RAIRRERMQRNKQGLAKIFGLGKSSKEKPGPLLELARQLYENLLAELHEDSETT
>SEQF2545_AGK84483.1 tRNA-pseudouridine synthase I [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNDVRKILLRISYDGTRFCGWQKQVSGSRERAPSVQGELEKVAEKIHHQKIAVIGSGRTDSGVHAVGQAAHFCTPMRNIL
AYRFIPAFNSLLPHSIRITDARDVSSQLHARFSAVMRTYRYHLHCAPVAYAHELPYCWHIARMPDIHLLNQYAATLKGEL
DCTSFAAAGDKSASKSRYFYDTHFSFNHRVLTFEISANAFLWKMVRSLTGTLLHCEKKRCSVREFVRILHAKDRRLAGPT
APPHGLFLWNIRYPEHLLRAE
>SEQF2545_AGK84484.1 arginine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQDLCEMWRHAVARVLSQLQGPAVEPVEGAQLVMEEPPEPGMGDIAFPLFLFAKRVRRSPAQLAQQLCTLLEEDTSMCAY
GTPQARGPYLNVFLNKECVAAHTLDAIFAQGERYGHTQYLQGKRIMVEFSSPNTNKPLHVGHLRNNAIGESLSRIIAFCG
ADVFKVNIINDRGVHICKSMCAYQKFAHGKTPVHTGIKSDRFVGDWYVQFNRYAQQYPEEAEHDVRDLLQRWESADPHVR
ALWRTMNEWALRGIKQTYERTGISFDKLYFESETYTKGREEVRRGLACGVFYQMEDNSIWVDLSSLGLDEKALLRSDGTT
MYITQDIGTAIFRAQDWPFDQLLYVVGNEQNYHFKVLFFVLRLLGYPWAQQLHHVSYGMVNLPHGRMKSREGTVVDADDI
LDRLHSAAEEEIAKKGRENALKHAQCIAENVAIAALHYFLLQVSPQKDIVFHPEESLSFNGNTGPYLQYMGARISSLLKK
VQEDVEQKGPREVRCDPALLTHEAEWELVKALARFPACVTRAAQGHDPSVITGYLYTLSKSFSRFYHDCPILCEARPDYA
CARLELVRAVRIVLRTAMRLVLIPFLEEM
>SEQF2545_AGK84485.1 hypothetical protein TPFB_0832 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCSMSWKSFIIPVRWRCMAGKGKHSSAGLLFWLAFSLLMAVLFFLNRRNIDRVFSSAAVQGMFGNQDSMRVFDSARRSQA
GSAVESDAKATLPTQDVAQPDAPVAGSPAPADAGTEGKDVGTVSGAPGSAQQSRAITLCWVRIDADGKITREEVARTLPH
STVPLSDALRALFLGPSEAEAVRGLRTLIPEGTRLRSARVQEGVAVLDLSEEFQFNQYGIEGYLAQLSQVVFTAAAFPTV
HAVQFLIEGRRTEYLGSEGVWIGAPVSKSSF
>SEQF2545_AGK84486.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRMAFMLLALLFSFRNASIQAEDARLLQPKTNALDLVVQGVDLVLFAQDKTAISISTPPEKDVFFTEHEGVLRVRTRTEN
AEGTRRVIRIGIPRAQTLAWVKIIATGAHTTVRGVRAVWALLLCNEGTLALTESTLKSCTLTHTRGELRFEAAVLKRASF
CLNDVNARFTLLGSRADYRLICSPGERAWKIEGAEQRGAHYTEPARARRHMVISASASSIDVMFKAPPTQQEAVDTTQKG
>SEQF2545_AGK84487.1 tyrosine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNPALARLQARGFIRQCTDLSALSARMDAGPLTFYVGVDPTGSSLHVGHMLPMFALKHLCDAGHRGCVLIGGGTARIGDP
SGKTSMRKMLDYATLDAYAGAIVAQLDHFLSFDHRHVFYVNNRDWLAHLNYIDFLREVGAHFSVNKMLTYEAYKKRLETG
LSFLEFNYQLLQSYDFLTLSDRYAVELQIGGDDQWGNIVAGADLVRRVRGKTVHGLTFPLITRADGQKMGKTEQGALFLD
PALVSPYDFFQYWRNTPDEDVRRFLLLFTFLSVRDVEAILTQGINCAKELLAYEVTRLMHGTAVAQVALQGARAAFGGCG
DKCALPTFELTQCTLQVGIKVTDLFVQVGLCTTKSDARRLIAQGGAFVGLQRVADIGAVIDQSALDLDGTVIVRAGKKRV
VRIVTDVLE
>SEQF2545_AGK84488.1 ankyrin repeat protein/putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHIHNRGIVWFVGSTFACFLVLLSCTTTSSPSPQASVDLFEMVARGDLDTLKTRFGKDSVNVRDANGDTLLHVGVLRNDA
HVVDFLLSMGADTEAQDASGSTPLMVAVTENCFESVRMLIARDASLFSRDAQGDTPLTRAIRKGTAHELVTRKTLLQKDK
SGKTPWHWAVRALDRDLIKHLVTLGPPTQERDADGHTPLSLAYSSSSDARAAEVAADLLLGGAELMHGSFSEFEIAVLKR
NYDLHFTDGSTPLHVMAKRGYTGFVQFLVDRKVNLNAKNLSSATPLHEAVRAGQVDAAVLLLRSGADPNVRDASGNTCLH
LVAPAPFRVRLVGALLDAGASVAIKDDYGETPLHVAARLGMDRAFVERLVGAGADISERNKKGETPLVLTIDRDHRDLTA
YFVSLGADIHAEDMRGETPLTKALARGLETVKIVVTDSNLYKQDVVGRDPLHVAVSRRAHLDIVKFLFREPKQMIARDTM
GNTLLHYAVANDDRAVGEFLMREGADIFSTNVHGVSPLKTALTTSGGREDWILTAANVHAQDTGGNTPLHLACEWKLTQA
INGILRKGAEIEARNLNQETPLFSAVKSDAAEVISILLHPQAGNPALVDARDAVGNTVLHACVRWSALRSADVLIREADA
RHVSLLNARNLSGKPPLHLAARAGNVDFIRLLLSHRVALHMGDETGKSALTDAVLADQEESVHMLLSAGANPVQQDMYGR
TPLHEAVLCNSQSVIAALRAAGGNPFARDSYGTTPLSLALLKGDTFVGAVVGKDPLLANSDGQTPLHLAVMENVPVQTFR
LLLAKGYPIDKRDRMGSSALVLAIKKDRSDLCHELLALGADLFIANNVGESPALLVLSKNTSILKTLVGFAVNKTDSAGE
SILHYAAKVADEKTLQGLLAMNRFGKFLRNVAGETPYDVAVRWSRPKIAALLKE
>SEQF2545_AGK84489.1 hypothetical protein TPFB_0836 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTRSQWHALAAFRTDLKAFCVQSLRAFGYPYMDPHAAQSAVACCTPQAFLHRAQAALVRAQGIPTYPVHTPIVYPHALEE
LTQSDPVPALILVSDNPGKEEQLHTQQRYLVGQSGRVAQGFFSRHAQLGVDFRTDVMLLNKTPLHTAKTVQLRALVRLLA
QDPAGTARARQVQSFLHRSQCWMARRTCQLQRSLGCDLWIVGYSELKSGHLFEPYARLLQTVCDRRTPLFVFQHFSMNCF
ARDFAKARARSPQQQVRDTLKDLGLHHRQQILGF
>SEQF2545_AGK84490.1 threonine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGLCVEENITMLQKRSDTLDRLRHSLAHVMAEAVQALFPGTKLAVGPPIDYGFYYDFSPPRPLCDADLAPIEEKMRAILR
AGCPFVKEVVSRPDALARFKDEPFKQELIERISADDTLSLYHSGAFTDLCRGPHVQSMRDINPHAFKLTSIAGAYWRGNE
RGPQLTRIYGTAWESEEDLHTYLRMQDEAKRRDHRKLGPALGLFHLDEENPGQVFWHPEGWTLYVAIQQYLRRVMHEDGY
AEVHTPFVMPQSLWERSGHWDKYRANMYLTEGEKRSFALKPMNCPGHVEIFKQKTRSYRDLPLRLSEFGSCTRNEPSGSL
HGVMRVRGFVQDDAHIFCTEAQIASEVTRFCRLLARVYADFGFAQEQIRVKFSTRPEQRIGDDATWDRAERALAEACEAA
GLSYEHAPGEGAFYGPKLEFALIDTLEREWQCGTIQVDYQLPSCERLNAEYVGEDNQRHMPVILHRTVIGSLERFIGILI
EHYGGAFPPWLAPVQAVVIPVAPAFLEYAQHVARELCARSLRVQADVSAERMNAKIRTAQTQKVPYLLIVGERELRAQQV
AVRPRTGPQHSMGLSAFSTFLLAKLETRALHA
>SEQF2545_AGK84491.1 ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MITVTGMSVQFSDKPLFKGVDLKFVAGNCYGVIGANGAGKSTFLKVLSGELEHHQGSIAIASGARVAVLRQDHFSFDQHT
VKDTVCMGHPALYRVMKEREALYAKSDFSEADGLKASELEGEFSDLNGWEAENCIEQMLSGLGVDEAHHDRMMCELDESQ
KVRVLLAQALFGNPDVLLLDEPTNGLDLYSIAWLEEFLIEFPNTVIVVSHDRHFLNSVCTHICDIDYGKIRLYSGNYDFW
YQMSQIMQRQVKDQQKKREEKMKDLREFILRFASNAAKSRQATSRKKIYDKLVLEEIEVTGRKFPYVHFKPRREIGNHVL
SCDGLRYAAEDRMQGGSCELFTDMSFTVGRTDKIAFVGQEHRAKTILFDILAGEKQAHAGSFRWGQTVSVGYMGKDTARY
FDCDLSITDWLRQFSDDQDETYVRGFLGRMLFTGEDSLKSVRVLSGGEKVRCMLSKLMLSGSNVLILDEPTNHLDLEAIA
SLNEALVQFPGVILFNSHDHEFVSSVANRIVEITPRGIIDRMMDFDSYVKSEDVNATRAQLYGGSVQQLRI
>SEQF2545_AGK84492.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDKKARAHTVIVCLVGALSLACAYLLGGSMKYLRGDVSRFWTSSRMQRHPAHSSQPVVRTFTDADGYTCLDQAHPHTIVI
DATRVRVSVQVCAQRRSLAYKVVKNSVYDPLSIHLDPTMLVLRRGKKTVRESTPPADSPGVMQSALNVRDTLRDWFYTFW
KNVWGSRWGHSVVPIEAIICVPAQHNVHNLKVRVKDSSLRLEGIEVRFADVYAHASELKLNGVRTDRTLLHTTDGDTQCS
RCVLSDAHLYTDRGTLSFDGTLQGNSEIGTRTGTVVARFTERQSYYALSVFSGHGAVYINDQRVRKTLGTCLSTGGSAQL
CVRNERGVLHVYFPQ
>SEQF2545_AGK84493.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSGEYQSFTLKRARRVYDQYNVINSLSFALVTGNTITLYALLLGARSTTVGLLSACMHFSFFALPLGKLVCRRFGVIKTF
AYTWIARNTSLLPMLAIPHLYAQDYTALALYVLIFSVALFNFFRGMGMIANNPVITMLAPGKHRSSYIVRISLANNSAIL
IATLLLSGALSVNASLTTYHFATALGIALGFFASFLLFTLPTVESCEHVQHTSPETPRTSPRSGYTTILRALKEKNFRTF
TFAFFVSSFATGIVRPFVVVFAKDVYHTPDSFITILTVCASGGALIVGFIMSLAIDRIGAKPMYIISSVLSVLTLIPALG
TPGLHSSFLSIAFLCLFCATTSMGFTGQDNAAQSYFFVLVPEDALIDVSVLYYLILGITGGAGSVIGGVVLDFCHLSGYS
SLQAYRIFFTGVSAIMIIGIALQTQLRNLGGYRVLRTLATLCSPKDLRTLSLLHKLDFNENLETEQHIVQELSTIASPIS
AEQLGTYVQSPRFSIRASALQALETIPSLSTHNRNLLLRELREGTFTTAAQAARILGIHMVQQAIPILREALHSEDYLLV
GEALVALARTHDDESHFLIGHVLARTQNPFVVLRGLQALEMLNSVHALPPLFEILRTTCKNTQTHTEALLTLSVLMGIQN
EFYFLFERYRTGHTTVQALVREKLEESFAISRVTDATLEKTLERFTADARAGTHVVMWVLARAGEDLGTKTALLLSLTLE
NPLCAREAFRLLIGTWTATLFRKPALMCS
>SEQF2545_AGK84494.1 S1 family peptidase Do [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNILFTSFVCGVHAVCRSFFTAAALLVFICCSGHPSSARVPSADTTARRVAGDSGNAGGRTLLPVGVSRESVQLLERLQN
ANRQVTAEVLPSVVTLDVVETRKVRVRDPFGGFPWFFFRGPEGPGAGPGGGSGNKGEAEEREYKTEGLGSGVIVKKTGKT
HYVLTNYHVAGKANEIEIKLHDGRIVKGKLVGGDQRKDIALVSFEDADPNIRVAVLGDSDAVRVGDIVFAVGSPLGYTST
VTQGIISALGRFGGPGNNINDFIQTDAAINQGNSGGPMVNIYGEVIGINAWIASSSGGSQGIGFSIPINNVKSDIESFIQ
YGQVKYGWLGVQLVATDADTVASLGIAKGTKGVLAAEIFLGSPAHKGGLKPGDYCVKLNGKEVKDVNQFVRDVGALRIGQ
TAVFDLIRGGVPMTLSVRITERDEKIVNDYSKLWPGFIPLPLTEAVRKRLDLKASVRGVLVSNAQSKSPAALMGLKSADI
VVAVNDQRVSSVREFYAVLARQTREVWFDVLRDGQTLSTVRFRF
>SEQF2545_AGK84495.1 hypothetical protein TPFB_0841a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYPTHKRGKQYVHESLHVPARTQTPTDTARVKSSTQRYGYEFIPSSPVPATYTYTLPTVHKLLPACTISTPRTLKIAD
>SEQF2545_AGK84496.1 methionyl aminopeptidase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRIKTPEQIDGIRASCKALARLFDVLIPLVKPGVQTQELDAFCQRFIRSVGGVPAWFSEGFPAAACISINEEVIHGLPS
ARVIQDGDLVSLDVGINLNGYISDACRTVPVGGVAHERLELLRVTTECLRAGIKACRAGARVRAVSRAVYAVAARHRFGV
VYEYCGHGVGLAVHEEPNIPNVPGLEGPNPRFLPGMVVAIEPMLTLGTDEVRTSADGWTVVTADGSCACHVEHTVAVFAD
HTEVLTEPTEVERTG
>SEQF2545_AGK84497.1 DnaJ domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHFSMCPDTMASPWKVWPLVEDYYRVLGVSHRASTPEIKCAFRKKAKALHPDLVSHTAELECEAVARERALRRILTAYEV
LSDPGRRAKFDLLYARFCARPAPAGFDYRVYLRAQGTLCAMVELILFDLFHGFECDAVRAYLSLKCRPEGFNLATHLTRE
DFMDCGFVLAEELHVRGECYECFTLLQDIVFEELRCAYFRHFFPEVLKLAEHIALGTASVRGRNGKSCVYCARAHACLPA
QEIVTFYACLVEYYERTGDRRRARGYAQKMDSVR
>SEQF2545_AGK84498.1 glyceraldehyde-3-phosphate dehydrogenase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRVAINGFGRIGRLVLQAMAEQKLLGKEFDVAAVVDLSTDARYFAYQLKYDSVQGKMGSSLSAPAEDILEVGGHRIKCVC
GRGLKPSQLPWKDLGIEVVIEATGIYANESSYGHLEAGAKRVIISAPAKSSDASKPVKTIVMGVNEHEFDPAEHKVVSNA
SCTTNCLAPVVHVFLKEGVGIETGLMTTIHSYTATQKTVDGVSLKDWRGGRAAAVNIIPSTTGAAKAVGEVLPSTRGKLT
GMAFRVPTPTGSVVDLTFRTEKETSVADLNAMLKKASESYLRGVLQYCDEDIVSADVIHNQYSSIYDSRATLQNNLPNEK
RFFKVVSWYDNEWGYSNRVVDLLKFISQKR
>SEQF2545_AGK84499.1 hypothetical protein TPFB_0845 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTLWVDADSCPARVRVLVARAAARLGCVARFVANRPIPLVQSPHCIMVETQPVDQAADRHIIAYARAGDLVVTRDIVLAK
AIVDARISVINDRGDVYTEENIRERLSVRNFMYDLRGQGLAPETTSPFGRRDAARFADSLDRETAKLLRLARRREAKTGE
EQCDWPSAQGKSQTGRR
>SEQF2545_AGK84500.1 hypothetical protein TPFB_0846 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVSVKGQLHIDLLGASFSIQADEDSSYLRVLYEHYKMVVLQVEKTSGVRDPLKVAVIAGVLLADELHKEKRRRLVQSEED
LLEIGESTERMLESISKVVDEGFVCGRD
>SEQF2545_AGK84501.1 hypothetical protein TPFB_0847 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLNLGQVKVLEEKVAKAVHLVQMLKEENAALRAEIDGRGKRITELEQLVLAFQDDQTKIEEGILKALNHLSTFEDSAYGE
ALTQHAAKVLENREHAGLSEELTSRTQMEIF
>SEQF2545_AGK84502.1 ribosomal protein L20 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRSLSSNGRVRRRKRILKLAKGFRGRCGTNYKAAKDAVSKALAHSYVARRDRKGSMRRLWISRINASVRTQGLSYSRFM
NGLLQAGIALNRKVLSNMAIEDPGAFQTVIDASKKALGGGAC
>SEQF2545_AGK84503.1 ribosomal protein L35 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKMKTKSAAAKRFGVTGAGKVKFKKMNLRHILTKKAPKRKRKLRHAGFLSKVELKVVKRKLLPYA
>SEQF2545_AGK84504.1 initiation factor IF3 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MADNKSLRINGSIRVREVRLVDAVGQQCGVVPTPEALRMARDINLDLVEVAPQASPPVCKILDYGKYRFEMGKKLRDSKK
RQRLQTLKEVRMQPKINDHDMAFKAKHIQRFLDEGDKVKVTIRFRGRELAHTDLGFNVLQNVLGRLVCGYSVEKQAAMEG
RSMSMTLTPKSKK
>SEQF2545_AGK84505.1 hypothetical protein TPFB_0851 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQILDLPSFGYHFITQAHIPRGKDEYYLRFSQSAEPPRAWRPLSKEEIHTLIQKGNHCDTWHDVLVADPFDASLIRNSSF
AGLVRIASLERRLLRYHDFTVPTGITHSTLISCDVGENCAIHHCAYISHYIIGNHVILSRIDELCTTNHAKFGAGIIKDG
EQEAVRITIDPLNETGGRKIFPFVGMIAADAFLWACHRDRTLLMQRFESMTQQQHDTRRGYYGTIETQSVIKSCRIIKDV
CFGPGSYVKGANKLKNLTVQSSLQEPTQIGEGVELVNGVIGYGCRVFYGVKAVRFVLGNNCALKYGTRLIHSVLGDNSTI
SCCEVLNALIFPYHEQHHNNSFLIAALIRGQSNIAAGSTIGSNHNTRKNDGEIIAGRGFWSGLASTLKHNCRFASFVLIT
GKNYPAELDIPFPFSLVTNNERENRLEIMPAYYWLYNMYAIERNEKKFAARDKRKTKTQTVEISVFAPDTIGEIENALAL
LDSAIERAWVNAGNSALTAEDIVLKHPTKAQTIPVLLTGIEHSTRSTLVLKPLEARKAYRDILIWYCTKTLLSFFEQTTR
CISHFTSHDPKTITHNWVNMGGQLVPEDKFETLLQNIETGKFKSWHHIHKEYDALAATYETDKALHAYAVLCSLARTRID
APLLCTYVQHAITIEKYRVTQIHKTRCKDYLNPFREITYRNPLERNAVLGTPEEDQLIRTTEEESAHLCALYARYIAPPH
LG
>SEQF2545_AGK84506.1 prolipoprotein diacylglyceryl transferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLSIVYPSWIRPEIIPSFPYFRWYGFMYVVAFSIAYILFRYQVRRGELDKWSRVSEPVTQDDIMSFFTWTILGILIGARV
FSTIVYEVDLLYMRKPWLIFWPFSLQTGEWVGLRGMSYHGGLIGALVGGGLWTQSHGRSFLAWADVAAASTPLGYTFGRI
GNFLNAELYGRITDIPIGMIFPNVPLSDMFPASEPWVREFAQRVGIHVQEGARLVNLPRHPSQIYEAFFEGIVLWCILWC
ARRVKTYNGFLVCLYVVGYGVFRFFIEYFRQPDAHLGYRFSATQSSPIYLFQSWSDVSTGQILCVLMILAGLGGMFALSA
YHKRDSVRKARV
>SEQF2545_AGK84507.1 putative flagellar synthesis regulator FleN [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQIIPIASGKGGVGKSLLAANLSIALGQAGKKVVVADLDLGASNLHLALGQKGNKHGVGTFLMGASSFEEIMVPTGYPNV
YLVPGDSEIPGFAALKVSQRRALTVGLLKTHADYVVLDLGAGTHLGVLEFFLLSSRGIIVTEPAVSAVLNAYLFLKNVVF
KMLCAAFKKGTGGSIFLENLKSDAAAVQRMYVPKILAELERVDQRGVAVLLDRMRSFRPRLVMNMIADPKDVDKALKIRR
SCEQYLNITLEYLGVIYQDTQQNVALSSGLPIVVYKPQSLIAQAVYRIADKILQSEGEEASSIEDYEGLVERSFASAEAE
AEVDFQFRMDYLEDLIKSKTVCVGDLAEIIKAQQYEIATLRKQNLLLQRKINKTLRNA
>SEQF2545_AGK84508.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNARLCFFSRLIFCVLSICALPLVAQEDKLYWEDPWALSTERAAFVKVAYSHDVVAVVWQEVTPKNATSGEIRLSASFYD
GSTWHTVRTFSPPLLYNHRSPSLASVAVNRKNEIFVAAAFDAHTITVFKTTDFGKSFTHTVLRSQGSDIVAPYVSVASDD
SLLLFASHGSEDHFSILLCRSEDGERWTPFQEFLSTEFSRRLFLPSHVSTQAQEIVVFQAHHQEGERASYQLYSTVSFDQ
GNTWSAPVPVTQPDEYHNQRPFLDRLSDDRFAVTWERSERTSTRYEMCYAELDRYGRKIGTTLRLAEPSDRLITPNFVHI
DGTTFCVWAGESAGLNTIFLAQKKEGAWSTTAVRSSEDALLFPHAVRVDNHLEVFWQEGEGARARVMRLRPDQSVQPPTL
IAENFSPNAVRKGTRARVRIVFPRDSSGIAGYNYAWQCGVQPAAPPDYVAHFPDKPQIELEATQDGTWFLAVTVWDFAGN
KSAPAYLSYTRDTTPAACPQLQTPLLENTHALKSNTFTLSWNQPSTDAQGNEERDHTSFLWSLQQVAPLSALTSLRVDTD
VRTFEEFQQRCVRAFPIPVDVHGTRSRQSSVSFTNKENGIYRFSVYALDRSGNVSEPAVVFFALRHFVPYTAIRYVDVKK
DPAGSLQMSIVGNGFRAQGTVSQVYIDRDRKAPYDLVLHAQEFAVGSDNLISDIHIDNLKKGSYHVGVWHPARGVHFAES
RVTVSEMGTVKFGAYDYEHQVRWSIPHTGGLRVNFVSLFMLIALFLAGVVFAASLTRIGDIVGEAFVLKKQVEALMIGEL
MPSEKRRKAMALKTHGAGLRVKFILFALTLVISVIFIVSVPLGVRFSKTQKDLLAKNLFSRVQVLLESLVAAGKVYLPAK
NKLELGFLPNQTTALHEARYAVITGESEEPHEEGIDFVWATNFSDIETVLNEPEYRQGNSRFVDKRIAQILPAMEDLNRQ
VKKDAEKIAKGIADLTQEAVALALRTDQGSVRRRDDIQSITRQMDQRLLEIFSTFSNNAVGSYPEYRVDNLSKRHSSYLF
YKPILYRQRGHADSFVHGVVFVEVSTQELLEHIEGLQRDLIKMVFYVSLIALACGVFGAWILASIIIKPIRRLASHVAMI
RDTEKKEELEGKLIAIKGQDEIALLGRTINDMTEGLIKAALASKDLTVGKEIQKMFIPLDTNTEGRKLTSGYTCDDHVEF
FGYYEGALGVSGDYFDYIKLDDQHYAIIKCDVAGKGVPAALIMVEVATLFQNFFKDWNIQSHGINLSDIVSRINDLIEAR
GFKGRFAAFTLCIFNTVSGTVHICNAGDNIIHIYDAQQRKMKRITLAQTSAAGVFPSFMIDMKGGFGVETLTLRTGDVLF
LYTDGIEEAKRLFRNKRFELVLCQEQGLAHDAPHETHTVGQDGEELGAERVSSIIESVFLRKGFSLQKWHNPVEGEKFEF
DFSSCEGNLDEAVLALVAVEQVFRMYKHPRATNLDKIRVDKKVDMFLARYFVQYPEYCARKEVNSEYEEYLYYTFIKEDD
QYDDLTILGIRKR
>SEQF2545_AGK84509.1 putative outer membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRIHQRSAPCVPVLLFLFLPSAPLCARGSKDWTPPQLGEVIESTEQDLAEFDAGLFRADRILDRHDLYRKTMHQLFSTLL
EEPKNHAKHLQLIETLEKLAGPESKEIHEFLNRLRNSSTYAVYAARFFHLMERARILMARQEYLKAALLYRSGYELYYDE
YLADPSSPGKKKVRARVEHAHAHVSRAKPLLEAVAAARAQYQNTQKRTYAASAHEAARARDAYSAAPAAPAAPGARAPSA
AYPHSLTVEAELRILQDFSKTTEESAALTSLVQALGALLKFSRDIEHTGVVFEQLSTRAQKNNETQEAFLAVARKITLGR
SKLEFEGILGALQAPAFDAFVDLFEAGRAHVAALHDQARAQFTFAHPPHSGRNIPAPTDTALASAGAWAAVGAGPAGSLI
PGAPLSAGVGSRGAWGALPAPVEPLLRQADDALGALARLWAACAPLGAQHGRFPRDYETFGAQIVALSAHADALRATKHA
YDFYHALLAFQRAPTVPVSAALRRQDLSQNEAFARDLSELAHHQEFLRRALAETESLSPPADTASTPSPGGAGDTPVPSQ
ADKGGAKQSAAPDTAQKAVAQKAGASEEADASSSPSEMAVRAARAQLHAIQSELLRRFTALKRNRYTAHMAFHQHSGVSA
LAEYAQQLTSAEEALRFDAKDERRVRALSFVSETGPQQVSKDMEALDRLLSFFSGEEEFLSERGYAYGLQSLRDLRTQFE
QFSARVQTLFLAAEQRAIHERLARQEAEYRYRQAVEGLGQDDFGGARKNLVLSREKADLALSLRYDTGYATETDTRLSTL
DSSINRRENELVVKDVRAYIAQAKDKYYKGEVLDAERLLIRAKNRWAVTNVTENGEITNWLSVISTAVALKIGRVIPDFA
PLYPQMSQLLHHAEQLYLHAAYLNASQRQEMERLLATSRENIHKVLLVYPLNERAGQLSLRIDQLLDPRSFRQQFAKKLD
TIRGTYKTESKKAYSLLLDLYAIDARFSGIEKLKQEVEIYLGVRLPPPNPQAIAQSSNFTLAARRIFERRDAALYQVAIQ
QLDEALKLNPDNDAAAQLKDRIQSLTGDGAVNVLSSEDEKEYQRALQELQKGNKLVASAVVEQLLQKDRNKKSAKIQQLK
KRIDAQL
>SEQF2545_AGK84510.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVHYKSVFYKSAALVCGFVLAGASVAIASSEAAAKTRSKMSEFKRRAVSSPSGGRLSVLDGSFTALANDASFFEANPAGS
ANMTHSELTFAHTVGFNNSHAETLSYVGQRGNWGYGASMRMFFPESGFDFSPSTGPVCTPASNPIKKLGAWGIVNFSRRF
GGLSIGANLKAGFRDAQGLTHLSLGTDVGLQWVGNVAKFFSSAEPNMYVGLSATNLGFTVKLPGSPFVLCRATGEQCCKT
CSGRCTGVGTCCNGEKPCCKDCDCNCPCQDEATPGSRHATDTMLRAGFAYRPLSWFLFSVGVATRVNVSNLQVDHLWKRS
SYALGMILDPVRFLTLLSGVAVNANGKVRAGVGAEIRVACFQVSASYRYDSTGDEQQGTPHNMSLGASILLGRK
>SEQF2545_AGK84511.1 hypothetical protein TPFB_0856a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRSLRACAPTLTADVADVTAVSRVQLNAGNARLCTHSHSHVSLVVDAEARTQAQEAEGIKHGAYAVSQILVQRLGVTSQG
LHIHAGGGTKAKEEPAEGPVRKPCTQHGVCRVHRTFVFAVLTGAVTAFALLRAARTTVAAGLLLAATTLFTGTRAVLYLV
RDLYGQSQVGGRKPDVQVGLLRGKGLGNVPHPLQTDVTGDRGVLQALRVAEPRLQVGSQGETPDTPGKVDDSNCPALLNG
GRSRCAHGLRGGRKVKPGFGEKHTHRRAVSPVARLANVRERFGVKRAKASGMEESHLPVRHVRTSCRICLKETCIICQRG
KRTVQRRIPPAGGRPHRPPPQFLHLPRRLGFCSGGRSHSGASQRQRAQERSAPIRKCMSDHGAHCNARARSWQAEHRRSP
RKPRRTRGEKKGGAPGQPPLAITQRWRRALYLRPSRIEAPSDMLCGVPCCSSPVES
>SEQF2545_AGK84512.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLRLPTARACITMGTMIRHTFTNRCGALLCALALGSSTMAATAAAKAKTTGQMQKLRRRPVWAPTGGRYASLDGAFTALA
NDASFFEANPAGSANMTHGEVAFFHTTGFGSFHAETLSYVGQSGNWGYGASMRMFFPESGFNFSTTTETVCTPASAPIKQ
RGAIGIINFARRIGGLSLGANLKAGFRDAQGLQHTSVSSDIGLQWVGNVAKSFTSEEPNLYIGLAATNLGLTVKVSDKIE
NCTSTCEKCGCCKEKSCCNGSTCCTKKCEGCNCPCQDCKDKGSVYATDTMLRAGFAYRPFSWFLFSLGATTSMNVQTLAS
NAKSLYENLAYSIGAMFDPFSFLSLSSSFRINHKANMRVGVGAEARIARIKLNAGYRCDVSDISSESGCTGAKASHYLSL
GGAILLGRN
>SEQF2545_AGK84513.1 hypothetical protein TPFB_0859 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRRPCVSAAPVRVGGRLVFGFARVGLRGLCLGALLLSPRIVLAQHVADAPLGARGVIPRSSLPRRTRAARATTLRSRGG
VVSSRASGGTLVVTAQKPKVMARNDVDYRPLSLQAGGRQGSLDLVATATADDASFFEANAAGSATIPRMTLAFFHTMRIS
DSHIDVLSFVGRAGRTGYGVSARAFYPDMSSKTTGFVGIFNVSHAFSSAYRFKGVSVGANLKVGYRHTRGGGGESNGKAQ
KSASGKENHHIVLTADVGVRGAWTVSKNFGAHEPNLWAGVAFRNIGASINATNLHGNNGAGGSGGGGGGNGDGKPAHVTD
SRVILALAYQPVRYFLFGAGLEWLYNVGSIKAVNSLRYGAAFMLFPLRQLAFSSSVVMKGMGPQQVRASAGAEVQFSHVR
CTASYSYLWSKTPTRPHYVSIGVAGFLKPVPEQPLWQEVYRSYLRGLRHYHAQRYAEAIAEWKRTLQQGVSFEPAREGIE
RATKLLQLNQKVHDFNIF
>SEQF2545_AGK84514.1 glutamine--fructose-6-phosphate transaminase (isomerizing) [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCGIVGMVAGRDVSGLLLEGLRRLEYRGYDSAGIAVVGSDCALRLLRCEGRVQSLCALLGQSPLCGTMGIAHTRWATHGK
PCAANAHPHCSESVAIVHNGIVENHRSLREMLVTRGYCFHSQTDSEVLAHLLHWELRYTAHLLLAVKKVLTQVRGTYGLL
CMDAASPGRLIAARSGSPLAVGLGCGENFVTSDPLALAHVTQRFLYLEEGDIADVHRDSVCVHDAQGNVVARPVVTYQMQ
LCTQDKGTHRHHMHQEIWQQPHAIRHTLNAYMSFSSSSRAQVRTFGEDRVLDGTSCKTFERLFRRITRVRIIACGTSYHA
GLVARYWFEAFAGVGCQVEIASEYRYRTSVVHAREIVLTISQSGETADTIAALRLAKTQGYLCAIAICNGARSTLVRESD
AVLLTHAGSEIGVASTKSFTTQLVCLLVLTRMIAQAKKILTQEPEDALSAALQRLPQDVERVLECEADVARCARHFVRAQ
HALFLGRGELYPIAIESALKLKEISYIHAEAYAAGELKHGPLALVDAQMPVVVIAPASPGVLFEKMASNIEEVRARGGML
YIFTDAPEHFGPVCTPEADAPEGACSQIVTVPSVSPLTAPIFYAVPLQLLAYHIALLKGTDIDQPRNLAKSVTVE
>SEQF2545_AGK84515.1 hypothetical protein TPFB_0861a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRWTVACGAARGLVESEWFLRVRVFCGFEFNVLPCAFALKRRLCVESLGWWRGVMSQVSCLRGCVVLNTAGMILQGSLS
LARTVRSAFYAVRVVFSRSARY
>SEQF2545_AGK84516.1 peptidylprolyl isomerase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MILKKEAAGVCSFALLLLAGMSIFSCRKGAEGVSSAGEAADKKALTADQLDPRKVQEQERQKTPLSKKSVGYAFGVLMGV
TLQDSKLDVDLGQVWKGLKKTVSADKDKQALADAQDVLQRAFEAYRQKEVEKNSQEAKAFLEENAKKPGVQVTSSGLQYE
VVKAADGPKPQGGQRVRTQYKGTLLDGTVFDASRDKPAEFPVDGMVPGVSEGLKLMPVGSTYRFYVPSSLGYGERGIEGV
IPPGALLVFEIELQEILPDSASKK
>SEQF2545_AGK84517.1 bifunctional cysteine sulfinate desulfinase/cysteine desulfurase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNLYLDWAAAAIPETRLILRETQQACTLFANPSAVHCLGNDARDALERARHTCAQSLGINPERLIFTSGGSEANQLALLS
VLTRLPHAEISVSMLEHASVTALLPRLERLQVSVRHIPVNARGFITPEAVRATLSPRTTLVCVSAVHSETGAIQPLPAIA
HVLAHTGTRGRSIQLHVDAAQAFGKIPLNLYMDLPRIEEHAQENNAPQTPPGYPAPTAQRALTYSVAISGHKIGAPRGIG
LLCAHRSFTPFVLGGGQEKERRPGTENLAGALALAACVREGAFFRTLHTTPEGPTPHTKPTAPAGLRSVRARTCAFVRAL
SDLPRVQLVPATRKEDEAHFSPYIVCCAVQDASGEALVRAFSDAGVCISTGSACSTKKGGVSTRLLRALGVESRATRGVL
RFSFGPHTTAEDLDRVLTLFRTLLQKL
>SEQF2545_AGK84518.1 LysM domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRPARCVLYTGRAPCGSKTGGTLLGTPPPVALQAKCSTPGINVPIPPVMDVITYTGADLVPDHARGCEPFSACPSPAEVR
RAVLSSSAFSDSGGARARTRNRLVPRFPLEEEIISFHESPDTLDIPESGSGVSGRLGGGRGLRARYAKWSTRAEARLIRA
QALNASGLLSSISNRSVRVSRRRGIGGMRFFRREKSARTPLARTAVPRFSFPSFSVPVRSLQDASCVPLCAALACALLFV
LMVLCIPWAVHVTGGRRLALVRFETDSTLAHALRRGVFRAEEVETREGGANAAALAEALDTQLATVSYRTYTVRKGDTIS
AIALRAGLKHMGTLLSVNGISNARRLSVGDQITIPSMDGLMHTVQKGQSLSAIASLFRLPLNTLLDANDLVSRALTVGQR
LFIPGAKLSAFDLRKVLGELFMYPIRGRRTSGFGYRSDPFSGKRSFHNGIDLAAPYGTQVKATLDGKVAEIGYSRIYGNY
LIIVHGGGYQTMYGHLSSVMVGRGARVVQGTTIGRVGASGRATGPHLHFSVFKNGSVVNPLKILTK
>SEQF2545_AGK84519.1 putative outer membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRMRRRRACSSGGACGCAAVRGARSFLSVRVLGMRIGMSALCLAPLFARTASLGAWSSQGGEVLGEVRARVPAHRRVRR
AVSGTSVTPVVAMAAQTSGKQKGVGRRALSLRTGGRYEMLGLAFTALADDASFFEANAAGSAAFPYLLVGGFHFARVNQS
HTDTIALVHSIGRTGYGFSASVQYPYLTMEGKTVGGVAIFNVAHRFLSAYRFKGISVGTNVKVGYRDSSAGGSGQKKRLG
GGGKKHVVVTADIGLQGTWSVAKNFGSHEPNLWVGGTVKNVGLSVEVDASGSGSSTGGGRTVHATNSSFILACAYQPIRW
FLFGTGIEWKYNVQEFADKNRFRYGVAFLLLPVQYVAFGSNVFLTGLAPDIRASAGVEFKSTWVRVDLTYTYESDKDEHV
ISCGIAGFFNRDRRKHLEKEVYTSYLRGLRLYDAQHYEEAIAEWRRTLQRAGSFEPAREGIERATKLLQLNRQVYDFHFL
H
>SEQF2545_AGK84520.1 AAA domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSFSAFGYEGEVIKVEVDLRRGLPVVDIVGLPGSAVKEAKERIRAAIRNAALPFPQERILINLSPADLKKEGSAFDLPIA
LAVLRAQVHASSAEETPELTGGARGCAREVRRVMVLGELELSGRIRPVRGTLAAVAAGLSAHIYDYIVPKENEAEARITP
GVRVFAVQELRAALVACQQLAVEPQNAPREQSAPGWGQSNSVLLWEGKQVSVEDTAHRVHLPADTGASVHQDAGMDAGAI
MALFPKRCPGAVGETGARPEGTAPGVSPFLFSVGRSTGDASDSAGGTGQERPVQHWPHAALGVTGGFEDVRGQRKLIRAL
QIAAAGGHHLIAYGAPGCGKTLSLSRFALLLPDLDARTALEVTRVHSIAGLLPKGAEQDPLMRRPPCRTPHSSASAEGII
GGAGTCLPGEISLAHGGVLFLDEATQFKRPVLETLRTPLETGQITVSRAGKSSTYPARFQLLLAVNPCACGNFGVQHKVC
TCAPQAVERYWRKLTAPLLDRVDLRVEVLPPASHTLLSEPACCTARLRKTVACALEAQWERQGSCLCAPINGRSSTVEDW
IRYRNARLSPENVQRWCMLTDDAAREFHRAVGKEQLSGRGGHAVLKIARTIADIEGVARLQVAHVQEAVALRTWSALLPH
SLM
>SEQF2545_AGK84521.1 hypothetical protein TPFB_0867 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRWLCRLIGYRYGYAVCGGYRRQGGRCSAQLHAQYTRASHCVLRIAWEVNGADYELFRLWI
>SEQF2545_AGK84522.1 hypothetical protein TPFB_0867a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIIMHSSVESLTFLQDVRALQGPVHRTRAETGQSYFRKNGKGLEVFFAFFVTFLGRYVRVCVGYAG
>SEQF2545_AGK84523.1 flagellar filament core protein FlaB [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIINHNMSAMFAQRTLGHTNVQVGKGIEKLSSGYRINRAGDDASGLAVSEKMRSQIRGLNQASTNASNGVNFIQVTEAYL
QETTDIMQRIRELAIQAANGIYSAEDRMQIQVEVSQLVAEVDRIASSAQFNGMNLLTGRFSRTEGENVIGGSMWFHIGAN
MDQRMRVYIGTMTAVALGVRNGVDESIMSIETADSANKSIGTIDAALKRINKQRADLGGYQNRMEYTVVGLDIAAENLQA
AESRIRDANIAKQMVEYTKNQVLTQSGTAMLAQANTSAQSILSILR
>SEQF2545_AGK84524.1 hypothetical protein TPFB_0869 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRSCPKRARGVHWATGAALWCPSRMIFEKISPLQAFVWAVLRLFLKSFRTVFRGAVRAGCGVLACVRAYGFPPYGSKE
>SEQF2545_AGK84525.1 flagellar filament core protein FlaB [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIINHNMSAMFAQRQGGINGLAIAKNIEKLSSGYRINRAGDDASGLAVSEKMRSQIRGLNQAGQNIQNGISFIQATEGYL
AETTEIVQRLRELAIQAANGIYSAEDRMQIQVEVSQLVDEVDRIASQAQFNGMNLLTGRFSRESALGPMQLHVGANMDQN
EKIFINTMTASALGFFSDEGTDGSRSISIATVDGANKVIGTLDSALKEINKQRADLGAYQNRFETAYQGIAIAAENLQAA
ESRIRDADLAQQMVDYTKNQILEQSTMAMLAQANTQPQAVLRLMQ
>SEQF2545_AGK84526.1 hypothetical protein TPFB_0871 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSAYRYANLTNTKYIPSVYAVMATAGCDDRKIKRKEKGKRHAAPLSLMGVHKR
>SEQF2545_AGK84527.1 flagellar hook-associated protein FliD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSDVRIPGVGAGKYDNLIQSLMKKERIPRDNAAAKVKVYEVQNNALKDVERYARDLRDAVKGLYSFNNPFAEKEAHSSNE
RAFTVDATRDAAEQNHTLRVKDIAQGDAFLSDPLPADFRVPSGTYTFCIGEKKICVSWKGGHYRDFIRAVNKQGKDSLTL
SEIKTSGASRALLFRSELTGKSNRLSFEDAALDLALRLRVVQEARSDVFTQDVLSVGPGKHARLDFPHPLRAQAGLTLEF
VASLEGASIANEESRAHTPAQGGAPTSSHGNTASAAHNQDGAAAVRPTEPANGAPVQEETSSVFFEGVTVKNEASQGDLP
TTDGLEKYPAVDDKGDNPRAPGESQGTATHEGSGSSTDNADDTRSTGALAGSGKLALESLQGHALPLPPLVLTQNAPQMV
SIPLREYGDVRALILDNAQARGALTLRAIRVRAEDAPGGYVPVNPASQAQDAAFDFDGVHVTRGTNSITDLIPGVTLSLH
ERTEKTETLSVTPDVNAMKNAIIEFVAKYNRLMAEINIVTSNKSAIIDELAYLTPEEKKKETEQLGSLHGDSTLLMLKDR
LRRNTSNAYRAGDDGASRTLAHIGISTKAHASSGINTAQLRGYLEIDEEKLHSSLNAQKDQVRALFGHDSDGDLLVDNGV
AFTLTELLNPYLGRSGIFAIRSNGVDERIKSTEKRVETYDKQLEKKERELRHKYHTMDGALRSLQKQSDAIQNFNQSVRN
RN
>SEQF2545_AGK84528.1 hypothetical protein TPFB_0873 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGVLMDITINGHTLQYVIEHEKTIGEVLGAIEAACKKEKQTVSAVTVNGRELSANELDTLFCQSLDTDVTLNLTTLSGGD
VRALLREISTTLLARTAALQEIAVNMHSGNLAESYAMVSDFSALLKSLYHCFTLSDIADLDHGLRIKGKALHDYQREISP
LLKGLLEAMEEGDSVAVGDIAEYELAPVVRDLSDGILHMDMGVQ
>SEQF2545_AGK84529.1 hypothetical protein TPFB_0874 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKFDGLIRNLDHITRKDTYLYYREEFSAVACYSLFGRIHSGRVEFSVETTPVGEKSVQVKLVDAIDYPLLPLVQALKRVV
RLLIEKNQLPR
>SEQF2545_AGK84530.1 hypothetical protein TPFB_0875 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRCVSRSAQDTARWGTVVGRLLEEGSVVVLQGALAAGKTCFVKGLALGLGIQEEITSPTFTLLAVYHGRLTLYHMDVYRL
ASLEDFFDIGAQECVYGTGVCVIEWGERVASELPEYTVTISLRVLADGNREITVA
>SEQF2545_AGK84531.1 hypothetical protein TPFB_0876 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNILAINTVAHALNVAAEGAQGTAVVSIEGAHCCIQQQLVRALDVVVKRAGFPVQETQIVACPRGPGSFTGLRTGFAVAK
ALQLGVGARFIAVPTLRLAAHPFRAFTGRVLSILDAKRGRFFWNCFKSGEPLFEDSHNHAQEIVKKVDTRVPCLVCGTGT
ALFKSVMESQDNTVPFMYVETDAHEGAKTLLALVKVLNHSAATPGERGAPQYTTRTYAKGS
>SEQF2545_AGK84532.1 HD domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGNSDICSDINDIEELQSEEGDAPIRENANPIREDYNFIREQNPILGSGLDLIGSAKLPMLFLDSNLLIEYISAEANSLF
RGYYHLERKPFFNVFGNILSRKELEDFFSCVRSHSKGFTWRGTMAHKIRAKRALYTRTSFIPLSISDAQPSGYIVLFEDI
SDMYSQQISNMLSSLLQASKLKDNETGLHCERVNHYCRLIAEYLYDINLYPQVDTDFVENIAFLAAMHDVGKIGIPDYVL
KKRGGLNELEWELMKEHTINGALILSSYPDPMAKEIALSHHERWDGTGYPFKLEGEMIPLSARITSIADVYDALRMERSY
KKGFSHEQTTHMILEQSGKSFDPILARVFQKIHTKFNDVWDTLQD
>SEQF2545_AGK84533.1 hypothetical protein TPFB_0878 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRVMRSVDSRSSVTRWVCLTSVILFCFCIAVMRYGGVKKRRYFYGFCLHPRERADITEVILRFPREERNASRELRWMKKD
RQWFIQLAHAIHPAKQEVLERLFQYLFTKRRFEFITNNTRFFSDYALGKQPAVQMKFTKKNGAAIGDIYFGALNGTGLGR
YIRIGDNAAVFLTEDDFTPFFRDEKRFWCDTRQFHELFTQSQIQMMEVSGKYIVRSRTSVVFKEVEQFFARFSYVDVGPT
PTQWKESIVIHRGDGKIIRFRLQPAAHQEWTLWDAQSVHAYTLSAYTARYLFALISRMQTETGMSSLQQFDTEENLISD
>SEQF2545_AGK84534.1 GldG domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRKHHIPCTVMILNIMMSVFVTFCTPVRCDLTAQRAYSLSAHTIKLFESVESTVEITWFYSTDVDRYIPTVIYVRDLLK
EYAHQLSKQCAVAMKDINLLSQSLRKELGFVARRVTYTRNTASIAYDAYSAILVEYRGMARAVPFVSDTKRLEYDIARLI
IQMQQEMSADMMSRGIYVLAPPESLSTTYAHVLPRLQSEGLLPEILSISLPQLDTRIPLLILGSGYVDEHAVTLLDAFLQ
KGGNALCFVSGNSVQLNDQWTVEEKRHDFLINLLSTYGITINSDLILDEQSFAVSLPSVYETQYDRVSYPFWPVVTLKPY
THGVPVMVQAGIQFLRLFWPSSIRVSFPARVFESTSNHSLCMTAPFNIDPSVDHLKDLAKGKMPAPQAFVAFRDYPGKLM
VVSDEYMVSAIVEHTHNGENLDFMINCIQWLCGNDGLLMLKSKNPAWLPLKSFRDEQKFARIVHRARYLNIVAIPVLIGM
LFVVMQILYRRKR
>SEQF2545_AGK84535.1 ABC superfamily ATP binding cassette transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQCKQFFTLYKKELRSLLTSPVTYVCHVLLHLGLTIPFIGVNFWLNAGISELQSFFLNAPLLFCIIIPLLTMHVWSHERK
SGTDTLLFSFPIAERTIVLTKYLSLLSVYGGMIVVSTAIPLSIFSLGYFDYAPCALAYVTLVLFGAALLSLSCAVASYVS
YAAVGFVLNFTLAVMALLVHIPARVFISHRYIRACVSWVSFVYHFESAARGIFDLSDFAFYIFVAIAGIELQCLIVRVRF
R
>SEQF2545_AGK84536.1 ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEVLRVTSLTKHYGSRRHPVRGCEDVTFCVERGQVCGILGLNGAGKSTVLRVIGGLIHPSSGEVYACHCSLSRYPVGYRR
HIGVLHEQNPLYADMTVEQHILFVARIFQLADGEARTAEMIELFQLQSVAHRRVRNLSKGYKQRVGLAQALVHRPKLLVL
DEPLSGLDIVYLKEFHKEIVAQNNNLAVVFSTHAVQEIEALCDVFVLLHAGHVLFSGNRAQIAARIVREFPEKKQTVALH
LETGTFIAFVFEQYMQWQSAQDAACYAV
>SEQF2545_AGK84537.1 HEAT repeat domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHLRSDSPSVFKIERYRMERRGNGVKGSSLFVHYCSVHVAILFLGRGVPMFAKETGTQHVQEQERHIDITDEKTVLLKKR
MNTIKYGLVSDIISLIEELKKENNASLNETLCMLCGRTKSSELKALLFDFFLFQKNDCAQSVAVDVLQQVTEHNPMVVKS
AIRYISGLEARELTPLLREVLSSEVSQYADECIVALGNMGSTEDSEFLVRYYENIHFDDDKKTLIRKQNVMAALEQLHAE
HAFDFFKLVVMSSEENSVVRASAAVGLAGIGRSDAVEILSVLSEESDPILRIASIKGAGLLDTDEARNIVIEGFRDTHYR
ARLEALAVAERVLCASYFPYVLYRAQSDPVDAVLHKAVDLVAKYNLGEGNDWLRDVLLDEKKSDTLRARVAAAGMQYTIS
ALYQHIEKVMLDVVLNDTKKQLRYALGKAFAKTRTELGQTIAAAYLASKDVLTVGIGLDMYQTNQYSALSEHIEKIAGDN
KFGALQAKARQILARQKKES
>SEQF2545_AGK84538.1 hypothetical protein TPFB_0883 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKILQVYMLDMFLPIFFLVLVCASMILDAIDILVNLTQFISNGYRFSSLVKIWYVSIPHYVLLCCPLSVLFAATYTVRIL
YVQNEFLAIHFGGLSFFSIVGPWFGFMCFLAIGIFAFDNSVVVVSQSKKDEIIARTVSYAQGNSENDVVASSFDGKIISI
AGAYHRGQKVLVDMLVIMKNSNGTIQKLIEAHTAHWQKDRWVLIKPVVYTITHEMKLMVSEYLDSFELREPLELFDHQDF
LTKGMSIQKIKETLHTLKYASKPHRELSIRFYKKFYFPLTMCIMLCLSFLTGSFLKKRSLIMYIFCSVVLASAYYVVEMT
SIVCAREEYFSPFWGVFFPVLTFLFLIFYVWCAGFMQERQYRASSLRQSVCL
>SEQF2545_AGK84539.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLFVYVCEVVFKHILVGVLCFFLVFFVNNVLLFAQTLLTKHVSAADVVRLLLYSIPAALIYVTPFAVLVGSLLGLGRLRN
NLELLALQVLGVSPRFLIFPLLSIGLCSALFVFVFSDVVVPASFIRLRQVYWRVLSSVPSLGFESHTTRKHNGVILSVGE
VFHSVMYQLLIVDKSDSRSLKVVSSRKSVLESSADQTVPFTIRMHDPCMLIVYRTRPRICDLIYGGRADYHVHTQQTQPE
YFMGLGPGGFSTCSLYREIQEKIKAKENPRHIATYQLEFQKKFSHPISVVLFIFLSFGLSTLSNISSQGKGFVGGLIVVL
GYWIISIGGQELALRLSIVPSLALWIPNAALFFTALILSMRKSAV
>SEQF2545_AGK84540.1 dUTP diphosphatase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRVRAVVYPGASFPEYQTLGSSGADLRAFLPGGPLEVHPLGRVLVPTGVCVELPVGLEMQIRPRSGLALEYGVTVLNSP
GTIDADYRGEIRVLLVNLGLAAFVVSHGDRIAQAVISSVLRVEYVRSGSISLTERGKGGYGSTGVL
>SEQF2545_AGK84541.1 polyribonucleotide nucleotidyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKHSITGTIGDHPLLLESGYLARQANGSVYLQCEGTAILATVCSSAQRQEGLDYVPLTVDFNEKYYAVGKMPGGFIKREG
RPKDREILISRLIDRPMRPLFEKEFGRDIHVVPTCISSDMVHPHDVLAIVASSAAVTLSDIPFHGPVAAVRVAYLNGSYV
INPTFSQIDAASMEVVVAGTRQGITMVEGGAREVSEDLMLGALEQAQEHIKALCDMQERLRGLCGKEKQTVIPSSAQLVG
RDRIYELAYPRLAQALYAQGKGERRSACDAVKRDVAQQYAAQLENDVQRRLFDALFHEMEYEILRLNILDRGLRIDGRAI
DAIRPIACEVGVLPRPHGSAVFTRGETQSLAVVTLGAMSDGQVYDDIEGDRRENFILHYNFPPFSVGEIGRMGVGRREIG
HGCLAHRSLSAVIPDPEQFPYTVRVVSEILESNGSSSMATVCSGTLSLLHAGVPIKKPVAGIAMGLITDGVRYAILSDIL
GEEDHLGDMDFKVAGTCDGITGFQMDVKVEAVSASLMKEALQQARVGRLHILSVMNQTISAPSVHISRYAPHIESFKIAV
EKIGALIGPGGKTVKSLSDQYRVTINTDSDGTVTVSGRDAQSVFDAKVAVVGLTEDPRVGRVYQGVVKRIVEFGAFVEIF
PGKEGLCHVSKLSRSRVSKVSDVLQEGQRICVKLIDIDRMGRLNLSYIDALEGKSGGLDTTK
>SEQF2545_AGK84542.1 ribosomal protein S15 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MALTKERTASVVQQYGSGEKDTGSSSVQIALLTERIRQLTDHCKVHPKDKSSNRGLLVLVGRRRRLLRYSRRVSMGAYRS
LVKSLGLRK
>SEQF2545_AGK84543.1 bifunctional riboflavin kinase/FAD synthetase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRIFRWSQLQEGACIACDRGAAISVGGFDGPHRGHAFLFDKVFAAACAPVADRARCTGLITFTHPPRKHKTSSYEGDLST
LRLRLRYFRARGFDFVVLIDFSKDFARIPGGVFFNTLLRAVRVCYLAVGVDFRCGHGLDTGVRELRRLGDAHSFVCDAVG
HYTLEGVRVSSSAVRRAVRCADFESARRLLGRAFSLDGEVIPWQQSGGCARTLCAERGRVSQTLPPEGEYAVRLVQGSGV
GLRAQLSVGSSLVQLRLGTEALSHGREALDSIEFE
>SEQF2545_AGK84544.1 tRNA-pseudouridine synthase I [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCRLSMPDAIVPFAKVSGLTSFAALAQVRRLLGVKKVGHTGTLDRFADGLLLLLVGGFTKLAPVMTRLEKSYEARIQFGV
QTDTLDPEGAVVRCSLFPTFARVRAALPHFTGSIDQVPPEYSALKFGGVRASDRVRRGEAVCMKARRVFVFDLQVLGCEA
DLGEFKKTQAGRGAAIADLDLTRVRAVTLYVRCSAGFYVRALARDIAAACGSCAYVSHLRRTRIGPFDLAQAAGVSRLGS
WTWGKERASCGAACFDVGAPPPPSSGGVATDSVSVGCEDLTVREIKQAVVSCDVDFANRIGLTACSVHAQYASRFLHGER
IRACWFQSFGTRRPGERALVFSEGRCLGLIRKAANGFSYDAVFCTE
>SEQF2545_AGK84545.1 ribosome-binding factor A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKQVSQLRVRKLGEHIRAEIAQLIMLGKIKDPRVSPFLSVNWVDVSGGMVCARVYVSSFMGKYKTKQGVQGLESAAGFIR
SVLAKKLRLRQCPRLSFVYDESVRDGFSLSRKIDRLESGGVQTEHA
>SEQF2545_AGK84546.1 initiation factor IF2 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTLRDNTPKDTSRVASEQAVRSPVTSGQTTSRTRADVDVKEKRLVIKKTIKVRAKKVVAKVTAARRVSCADENRTPGDAS
QATISAAPEDKKQGFPDIREDGVARGVSASCGAVQNAASAQVPGARTPGVIGVPVASKTVEEARGGGAKRVITKRVGGVF
VLDDSAARPNRTAGNLASGARLSRFSRSDRQRSDGFSGTQARANAGGVRRGEGRPFARDFSRGSTGGYRPAVRGPARPAG
RVGSGPRGPAPLQVGAGKPAQNKRSFRGRKQQTYQYQHKDRLELEEKLLQQKKKNKEKLAAVPRSVEIMESVSVADLAKK
MNLKASELIGKLFGMGMMVTMNQSIDADTATILASEYGCEVRIVSLYDETIIESVGDEHAVLRARPPVVTVMGHVDHGKT
KTLDAIRSTRVAEGEFGGITQHIGAYAVSTPKGSITFLDTPGHEAFTMMRARGAEITDIVVLIVAADDGVMPQTIEAINH
AKASKVPIIVAINKIDRADANPNKVMTRLAELGLAPEEWGGDTMYVSISALQGIGLDLLLDAIMLQAEVMELRANYGCCA
EGRIIESRIDHGRGIVASVIVRRGVLRVGDTYVAGVYSGRVRAIFNDQGEKIQEATPSMPVEILGLEGMPNAGDPFQVTD
SERIARQISLKRQELRRYENARNVKRITLDKLYESIEKGSVSEFKVIIKGDVQGSVEALKQSLEKLSTDEVQLRVIHSSV
GAINDSDVMLAAADSNVTIVGFNVRPTPQAAVLAERERVEIKKYTVIYQAVEEMERAMEGMLKPSLKEVVLGSAEVRKVF
KIPKVGSVAGVYVLEGVMKRNAIVHVVRDGIVLHSGKVSSLRREKDDVKEVHSGFECGVGVENYFDFRERDRLECAEMKE
VSRKLKDAALSDAARLQG
>SEQF2545_AGK84547.1 transcription elongation factor [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFGVSNDDIRKYAQEKGLDEDFAFKIVEQTLKAAYKTTFKTDENAVVTFGEERVCIYARKRVVEEVYDRVSEVDLSTALE
LDPTTSLDSEVLVELESEDFKRGSVQAAVQRITELSREIQKDALYAEYKSKEGEIIVGYYQRARNEHIYVDLGKVEGLMP
KSHQLPQDDYRQNDRIKSLVREVRKHPKSSVVQLILSRTDSAFVKELLAVEVPEIYDGIVEVAKIVREPGYRTKIAVTSR
RDDVDPVGACVGPRGIRIRMVIKELNDEKIDVLEYSPDPVIFIKNALSPAEVLNVVVLDEEKRSALAIVAESQLSIAIGK
QGLNVRLANRLVDWNIDVKTESQFEEMDVYTDTRRAAENLFDNDYQEESEFSSYVGFTPELIKILQDNGIQDVQTLVDLG
EEGLRALEGMDEAHVQELLAAIEENFEVVEEGEEASVTSSPGTGGDEDQALQCPECGVRITTDMSECPHCGIGLSFEFEY
EENEE
>SEQF2545_AGK84548.1 hypothetical protein TPFB_0893 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNFSPNTLGSFESCAEVVRSLGCALVDLQWSVSAVSRRVQQAQGRARAVIYSAGGVTLDVCARVHRILVPRLQALGGVRT
VFLEVGSPGERVIRNAAEFSIFLGETVKVWFCTGQFQVGTLAFADETCLTLTSGGVPVTIPYVQLTKAQLHPAVRA
>SEQF2545_AGK84549.1 hypothetical protein TPFB_0894 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEKKFALLIDGDNISPKFLEGIVGEVSKEGDIHVRRVYGDWTTPNMNGWKGLLTKIPIRPVQQFRYGDNATDNTIIMEAI
ELANNNRAINAVCIASTDSDYYSLALKLREYGLYVLGIGKRNAREIWVSACNEFKYIENIETEHFGLSAGFAFHTESDAA
AVPGAGVDAVEEDTGGFDLGKLIAHAYRNSRMTEEGWVSLSNLGKSLRITKPEFDPRSYNHSTLREMVEALPELFEVQSD
RRIPPNYWVRAVRGAHKRTVLYGVIKRFRERDRWGVISHEELGDFRFVYSNLKRECRATALPEGTTVSFSVFRMPNDQGK
SDEERHGRAADVLVVKRVAG
>SEQF2545_AGK84550.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCRRLCHHRWRVWGKVASLGVLLLGGLVACTSSAAGSTSNTRPGVRMTITSRYPFDRTMQLLESALRTQGFSVFGIVDYR
EAAHKQNLDIQPAKLMVVGFPKIGTPLMLEDPYFLLRVPLYLMVTDVRGKTRVSFHNTRGLMDSYVELSDMDQAIELVES
IVKKTLAE
>SEQF2545_AGK84551.1 Tpr protein K [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIDPSATSRYGSPRLVSNGFRHRRKVVYQRVGHRRFSLIFFFVVVLGRSPRLWAQVSFTPDIEGYAELAWGIAXXXXXXX
XXLKHGFKTTTDFKIVFPIVAKKDFKYRGEGNVYAEINVKALKLSLESNGGAKFDTKGSAKTIEATLHCYGAYLTIGKNP
DFKSTFAVLWEPWTANGDYKSKGDKPVYEPGFEGAGGKLGYKQTDIAGTGLTFDIAFKFASNTDWEGXXXXXXXXXXXPS
KYGLGGDILFGWERTREDGVQEYIKVELTGNSTLSSGYAQAAXXXXXXXXXXILWDVGAKVSMKLWGLCALAATDVGHKK
XXXXXXNGDIGADALLTLGYRWFSAGGYFASQAXXXXXXXXXXXXXXXXXHDCAAYIKLETKGSDPDTSFLEGLDLGVDV
RTYMPVXXXXXXXXXXXXXXXIHFPVYGKVWGSYRHDMGEYGWVKVYANLYGGTNXXXXXXXXXXXTKWKAGYCGYYECG
VVVSPLEKVEIRLSWEQGKLQENSNVVIEKNVTERWQFVGACRLIW
>SEQF2545_AGK84552.1 exodeoxyribonuclease V beta subunit [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTDFLFSFFQSLNAEQRRAVFSSHNAVVTAGAGSGKTKVISARYIHLVVERAIPVERIVVLTFTRKAAMEMARRIYEDLR
LCVQSASAQPEPGHEAYLLRAREALARFGEARIMTLDAFSHEIARVGARFFGIAPDFSLSEEENRALAHECAEDFFLEHR
EHPVVLHFLQQEHAEDCVRELFFIPLQDHGILTHPCDFRAGLAHQIATARGLLKTVLCDIHAALHAIRHHMQEADAQNAL
IARCVALFAAQDTAFSYTPAAEADAIADAFLARGYEEYAAKPDEFSVSDPDEGARRAAHDCLRYCAAVKTLFCLKGNLGG
RAGAAQAIKAQVKQLRLQLVPQMERLHAFFAQVPFLVALSSLLERLQARFIRQKRERNCLSHADVAHLAVQVLRQYPEIR
VSYKRGIDAFMIDEFQDNNALQKELLFFLAEHEARTAHFLPPAHALCAHKLFFVGDEKQSIYAFRGADVRVFRALAGVLT
PQVSGASKQELPLSAAAELQPTLQTLRINYRTEAALLERLNILFSHILRGPSESAENGYEVGFQYMQPARCTAGIEPQFR
VIGVDRHRFSRPEHEAQHSAARPTPQAGRTGASEDSEDSLSAQETEAWALARAIRAMVDGGTLVRHKGEAPRACTWADVV
ILLRSADKQSRYERALRLWGIPYTSLQTRGMFCDAPLSDLLAPLRLVLEPADRHVYAQVLRGPFVRVDDDTLSLLLLPPA
PPDAPFSYIPAELSAPAARCVRAGADFFARVQQQVRRLATNTELLTYLWYTEAYGTLLAQDPLARPYHVIYDYAFELARR
ADRQGKGIGEFLDFVDACLSAQERVEELELPCTDRACGAVQIMSVHKSKGLEFPIVCVPDAGSSGPQVMARVGAVHSPYG
YIPRFLPHPEGVHPIFVQEQDTRARAYRAELRRVLYVAFTRAECHVIVSGVLPISDGHPAPAVSRSLADICSLLPSGDGS
EPPSSLSFFSELLPALMHAAPLPPHPSPSVVPAPVSFDECLPLARPQAYQRALTGSARQSVPQASAPRDWYAAVPVRAPH
YYPRLVQPVTSLVSPAPGQNSASASPSPLTPQSPRGVEFGTHVHELLAQVFQSPAPTVALHSVQRVDSPAARLVACFLHS
PLGCRACAAPAHQRFAEFSFLTRAPGNTKPPHGAEYQAGTIDLLFLSNGVWHLVDYKTDYEEHPARYLPQLQHYARAVQD
LFSDHPVTAFLYYLRTGHEFSLEALESHFLKKNAVPDSE
>SEQF2545_AGK84553.1 hypothetical protein TPFB_0899 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTEIEACIKTVRTPYRRLFVFPSRIVAQGWLRQSLSLLGVRTVPGRLCLSWDEFKKRCFQCAPCAHRTPISEPLRLLFAH
SVVQRNARQAAEGRALFCNLIPPAYAQDGAVFVQWLARILPQLGSWQRRVESHCMPPKDAVSRNTFDGRDARAYAQSAEA
QDLQTLKAHYEQFLRAHALFEPSWDTPQFCAQGNTYVIVYPQLMQDFAEYAPVLQEAARATAGVLTFLPVPPFRQDTPLC
CFSNVREEITAVALQVERLLRTGTPVSQIAVSVANLEELQPYVEREFRLRDIEPEVRAGFCLGAHPAGRMFSQLREFVRS
HGTLKSVRALLLNPHIRWADPQGAQAVVQYGLQQACIRSWKQSGTYCNVWLQAFALHCERTEQERQHQQCAQRFFLTLLR
FARALVEARSFVRMQKAYGAFRAACLLPASAHTSGAEEEIASSAFASCSAGEDDAVMARCVCVLQELAALERRFAHVVPP
DPYSFFVQQLAQQMYVPVRAGVGLAIFPYRVAAAAPFLHHFVINVSHEASSVRYQRGTFLRADVRAAFGFEDEDVTEAFL
SAYATAQTVYFSCSVQAFSGVQRPNRFFSNVHPPVSSTLTGRASQTPSPAGIASETGGAVPQYPAVPYEEDALQAEQDLY
AQGAPVPSSLYRTQQERLRKAASLIPAAGRSYIRDSFAQALPPLTAVLHARHFHHAAVKVSQTDLNLFFRCPAAWFLERV
LDVAPLSRRPRLVDPRVLGVFSHVVLERLYNRIACEDECFFSAHMERYRLWTQEAIEQVFSERAVRAGPLVWALRAALSA
RIRHMVEFVLQFDAQRLDGWRVVRTEKAFEFTDTQCFYTGLVDRISCSPDARSLAVLDYKTGALPALSDYTDCEKKGRLS
DFQIPMYVYLLEQAGYTVTHAFFLDVRKRDFKVIVSNGRVDMGAKRGVDTVQFQAVMQRFEQSVAVFSKAVRQECFAKAP
YVTWLECASCRFAPVCRTSYVVRGAS
>SEQF2545_AGK84554.1 MATE family multi antimicrobial extrusion protein OR [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLHISSCCRGKRLSRCFGPRAFYVRALCIALPVMLHSFIQTGISFLDNVMVSRLGDVKMGAVNVVNSLLFLYVTALMTVS
NAGSVFMTQYSGARHVVGMRQSYRFKQYAMGSLALGAMAAALCCPQYLLSCLLGKNAQAAQIIAEGERYLSIIVYTLVPL
SFSLVLTSTLRETGKVLVPLAVYGCSAVLNAVGNYMLIYGNWGAPRLEVQGAACATLIARVVESLMLLVYVRVKKPDFYV
RLFCRCAIPLSLCTVMLRKSLWIFVGDMTWSVTEMAVAALYHSRGGAEVVAGMSAGWTLAQLFFLSFPASSVAITILVGD
VLGKSELKQAQDYARWLMNGAFFLGLGLGVIVCVARAGIPWAFGDLSHASQRIAQQLVLVTALYMPIWMYLNAQYAVARA
GGEVMVTAWTETLVDTLLFLPLMYVLARFTQLGAPLMYGIVKSTSVVKMVVLARHLKTRRWVRNLVANLS
>SEQF2545_AGK84555.1 putative esterase/lipase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRPIVAAQRVTIQETRAVLAARFLFTFCCFFTTLARYLLMAEHTSCTSIHPLVRSAFYAGGAHAVLLIHGYMGTPREMQF
LGRALHRDGFTVSIPRLPGHGTNREDFLETGWRDWLRRVCDEYRDLSAAYPSVSVGGLSMGGVLTALVAARFCPQKAFFC
APGFAVSDWRIKLSPLVRWFVREFAADAAPFYPEQDFNDATKDYRSAHYIAQVAQFYALQRRAIRSLACIRSTLLTILSR
QDPLVPCAAVQKLLDARVRSAHQYVVLEHSGHVITDDVEREQVASCVSAFLRT
>SEQF2545_AGK84556.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEQARALLQGKTVTIMGLGVHGGSCAAACFCAEAGARLTVTDLRNADALTPSLKRLRAYPSIRFTLGEHRLEDFENAHVV
IKNPIVKGAHNIYLSAAQRAGARIETDISLFLRLSPAPLLAVSGSKGKSSTASALCYSLRALGFPAFLGGNSTVSPLEFV
RHTTPATPVVLELSSWQLADLRAVDAQDHTVHHAGLLRPEIAIMTPIMADHQNWYADMESYVADKQVLYAHQGTHDTLLC
NADDGWGPRFACEAQKNGVRVFWYTAQSPETACRACTPRLMERALWRATDGTYWARFAEGDRACMLIPPQLHVPGRVLQT
QVASAALAALLFAQRHSLPPSSCPPCFCAHSHSPAYANHASPPDYACPSAHSPFQEHTRRLAQALESYTGIEHRLEFFYE
KGGLRFYNDSASTVPEATIAALEAFDESVVLIVGGTDKNADYQPLAQAAAKAHALYLLAGSATARLQPLLHAAQVPFYGP
FTSLEVLLQDLRARQKSPGVIVFSPGAASFELFAHEFERGTTFKSQVRIIFE
>SEQF2545_AGK84557.1 hypothetical protein TPFB_0904 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNKNTQDKGTPAALQVFLLPQYNRYSAEMTRHVPLLCNLFSMSRYVLRHLTAQIILERMSAACVCLRRRRQSEFTDPTEK
IGE
>SEQF2545_AGK84558.1 ribosomal protein S16 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSLRIRLKKLGSKKRPYYRIVVQDAREPRDGRAIEELGIYQPIAPKGTEVSFRLDRARFWLERGAQPSDTVRRLLQSRRG
SVLNAVASDERRVASSQQAADLAHVESVSCAAPIPSSPGGQGV
>SEQF2545_AGK84559.1 putative RNA-binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVTMEEELIAYIARALVDRPGEVTVTKSPGEGLEILQLRVASEDVGKVIGKHGRIARALRTLLSASAHASQTRYALEIID
>SEQF2545_AGK84560.1 putative 16S rRNA processing protein RimM [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDRIVTARIVSTFGVAGLLRLKSFSGEYAHLATLKQVCLAPPRSRSSGTLACALPREAVHMVEHVLLRAQDALLKLHRVD
TVECARTFVGAELRVPRAEACPLSAGEFYLADLCRCELVFEGSAVGVVLSVVEGGGSSLLEVQRTHGGVCYVPFHRTFIG
DVDVGRKKIELLQRWILE
>SEQF2545_AGK84561.1 tRNA (guanine-N(1)-)-methyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNIDVLTLFPAIPRVYFSTSIMARAVSDGIIHYNIVNIRDFAHDKHKHCDAPPYGGGPGMLMRSEPLGKALDSVDAPKKR
VVYVTPSGKLFEQGYARSLAQERALVLICGRYEGIDQRIIDEYVDDEVCIGNYVLSSGEIAALVLIDAVSRCVSGVIRHE
SLEEESFVNSLVEYPQYTRPRCFHNRDVPPVLLSGHHAHIRTWRLARQIEKTRRNRPDLLSAARASAAWTQEAESLLKEL
DYELPPHPTN
>SEQF2545_AGK84562.1 hypothetical protein TPFB_0908a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEREYTLHSNAIGIFAHRKGAPDAAIFKTQNEPFVSLDALCFSLHYFEMHTYGVPDAERFSWFLSLLVFNLLDEVATHSL
TP
>SEQF2545_AGK84563.1 ribosomal protein L19 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSCHLIQQIENQQRKEPAETFRVGDTVRVHFKIVEGKTERIQAYEGLVLCFKNSGVRRTFTVRKNSYGVGVERIFPLHSP
RIERVDVVRAGKVRRAKLYYIREKIGKAARIKARIVKKPSPSA
>SEQF2545_AGK84564.1 hypothetical protein TPFB_0910 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNGAVRVVLTEVPRTVSLTEGALVCVRILSSTHAGRALVAINGERVRARVPQPMHKGAVLFLRASIRAGTVFLHPQCTST
PPSAEDMSAHFLQRWGVSFSPEAAALIHAHTSLCVPLQPQLIERFALLLKKFPEQKRAHAAFLASILGDRNIPVDAAMLR
RMLSTFLGESGAYTDSDTERDLFALVNHTYHSALHWLLVPFERRGAHTVWRGTLSLLLHLHKKTCTQLRVRACNTAGEWV
FCVQNNVLTVQRHAARELSRTAQKKTVARLCALLRERGIDFLSVRYGAHADSANDAVPFKGIDVSV
>SEQF2545_AGK84565.1 FlhB domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRKRACSVALSYATGDKAPIIVASGTGAIAEKIVEIAKKFDIALVQDELLARVLSEHRIGACIPPETYQVVSAIFAFLY
TQQ
>SEQF2545_AGK84566.1 hypothetical protein TPFB_0911a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDLYLFTRLIFGIGAHGLIPRLMHTSGNITVVCTKRQRLQRQPDRFPVGYTHLSCAQTEHAPEVRLAPRRYQTFLQFQQF
FLQWRPCPKRQ
>SEQF2545_AGK84567.1 HD-GYP domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSQKIDVSELQEGMCFSEPVFFDDGENLLLREGEPVSTRELTVLQDWNIPYVVTAGRVLAEGESVPFSTVEELAEFEELA
AEELLDPEDDIVSTGELRTQDILKDICELLPKVCINPHYHEEYVGFIQELNMLFAKMNAHTTLPARPADMLAKRLSELVR
ANTLGFVSLVLSYKIEGFRFAKPAVDTAIFSIIVAQHLGFSEKDIFDLVVASLLHDIGMQHVPADILKKSGRLHFQEQQA
VDAHTIYAHSYIVNTLKYPNSVGLSVLQHHEHWNGKGYPQSLSGNKITIGARILAVTDAFAAMLAPKSYRKPFSGYQAMK
SLLADNARRFDPDVIKAMIQSVGIYPIGSLVLLNNSAVARVVKTTATAPLRPCLRIVIDEHDVTHPDDSGEFIDLAVNKT
NYIVGEVSPWSYAKAQ
>SEQF2545_AGK84568.1 hypothetical protein TPFB_0913 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPKHNKLLGAFGEAYAARWLATRGYIIIARNWRRATGEIDIIAQQDDTIVFVEVKTLRCTSYADLAIIVGKRKQKRICET
AKHFLASAREYNHMCARFDVIVLRSDPFRRQDVDIVHLPHAFEDLV
>SEQF2545_AGK84569.1 hypothetical protein TPFB_0913a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKGSVFPSRGRRSSRRVFCSETIHELEKKIQDQSYIEGAIQRLALILSKRLLSMRGIECD
>SEQF2545_AGK84570.1 hypothetical protein TPFB_0914 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTDVQSSGRRRKRKRTPRRDVFSPKLEFCEYVCPRCKEVIKDLPVALGDKDSGRPVHFDCVLSFLRESECLAAHEHVVYV
GQGKFAVIVFPNPASTTCFSIVRLIEWETKNTLLEWRAGVAKICSQVS
>SEQF2545_AGK84571.1 TPR domain protein/putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSSAVIVFFVVMLALSSIMLVATVASKVGTRSSRRKDKESLMREASRRLAQDPYDIRGLSVLGDIHYQDQEWEKAFAMYA
TLVERSSSSSQMEQFEILLRYGICGVKTEKYAEAKKGLLLAQGIDSHHFEVNYNLGRVYYLDRQYEQVVPLLRRALTSQP
DSAPAAQLLGYTFQKLQKYQEALPYLKKALDLQPEDKETLFVMGECFYEANAHDRALKIFNHLRVDPLVGPRAALYAGTI
KTKLNQLEDAAEDFEIGLKHDNIPSDVANELRYRLAQTLIKTQNLGRALVMLREIHQLNPEYRDVTALITYYQELNQNRN
LHLYMIAAQSEFIGLCRKVVSKYFPHARVKILDISVLNTHTDIVSEIDTPKWADLVLFRFFRSQGSVGELVLRDLHGRIR
ELKAGKGICMTAGAFTDEARRFAEGRPMDLYDKNRLTRILNSID
>SEQF2545_AGK84572.1 MgtE family magnesium (Mg2+)/cobalt (Co2+) transporter-E [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAMNENFEKIQTLLEHKRYVPLIANLNEMNEVDVAHVLDMQSPAQALLLFRMLPKNLAANVFAQLSSSKQSAFLATITDR
ELAPILAELAMDDIVDLVEEMPANAVKRILAQTGETERQVINQLLKYPEDSAGSLMTTEYVDLEKQMTVHDALCCIRETG
LKKETVYTCYVIDQNRFLHGVISLKKLVLSQGDLLIENLCERDCIFVHTHDDQEAVAAVFKKYGFLALPVVDTERRLIGI
ITVDDIMDVMQQEVTEDFQIMAAMQPSDEAYLETEVFTLVKHRIGWLLLLMVSETFTGNLIAGYEDLLVTATALTTFIPM
LMDTGGNSGSQSSTLIIRGLATGEIQLHDWLRVLYKELRVALAVGGILGTTSLVKTYFINGKPLALCGSVGITLMITVVA
AKLTGGLLPILAKKLCLDPAIMAGPLITTIVDTTSLFVFFNVARVVLRWPL
>SEQF2545_AGK84573.1 hypothetical protein TPFB_0918 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDAEDQNNTLQTAAPCRRGEHPARIGAVQAGANPAARTRRAAHVESMHARLASECLRKGIHLSSALSIVLAAWSKPLTLG
AIGTLGVGYYVAERWRLRGKTLPLVSLLTRAAARDRDKHERSLVRGPLTLAIGVSSAILLFPPPIAAAAICALAFGDGCA
SLAGTVYTFLRFKNSADSPGRRRGRTTTLFSVQGKTPVGSAVCCIATALSVHALGASGARSWGLGVCAALIELLPCKDYD
NITVPLGTGCIALLMSW
>SEQF2545_AGK84574.1 thioredoxin group 1 family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MALLDISSGNVRKTIETNPLVIVDFWAPWCGSCKMLGPVLEEVESEVGSGVVIGKLNVDDDQDLAVEFNVASIPTLIVFK
DGKEVDRSIGFVDKSKILTLIQKNA
>SEQF2545_AGK84575.1 hypothetical protein TPFB_0919a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKCSLGKNYARGYQIGAGVYSCIFSYPLHHSPNVQAEHTTFLISLTGDAHSL
>SEQF2545_AGK84576.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRARLYFQYFKAKFLKRRVTPPVDYEEIVSEFWRADFSSTEHARWHAETGDGYETARGAHGLTLHLRRKFLYAWSANPV
FRYKDCVLTARIRFLPGTHPPGEARALPNSEQPEVPASLDSTSRPACLPEAVAVDPSAMGEAVPERAGTCAAGLLFRYLN
ESTFYALLVSDGGWLRLDAVVNNTPLPLLGWTDTGASDEVRVLSLIAVGTSFTLCVDDQWIAQIEDDTIQAAGKVCFAAQ
NWGVHAHRSFELSAFSLESQPFMVETACLRANEPARIPASAHLRLAESLYAMGRAACARAEMKKLKAKCTFGLREYLLAG
DIACAQHLYDEAEEAFNAALVQDPHCMRALLALGGALYQQNAYEKLAHLLATHRVVAERDAFLSNLCGHLALAQNRHEDA
AAAYQRAFRLDPHQGLFALHAAQELSLLGEKEQAIQAYLHAARLFLAQESYADLERVVLALRRLDPERTEVRSIAGKLYY
ATGRHRQAHTQFDALCRAGSADATVWYLYGLLLREAQGTHEHDAPAAAACEQRARDAFQRACALAPDCALYHFKYAESLF
LSEKDCDEPLARALALDPDNGWLHNLCAQKALREQNFDAAAQSLQRARALLPHELVVLENYIELQRQRGALACCVPLFEV
ETQRADAAVIAQRGQAFHLLANAFYADGCYEHAAPWYDKALREEPQNVQMLVHKAENSIKLHLLHEADALLVKALDIQLT
AHVYTLIALVAAQLGDFPRAELTLQEACTLWPQCTEVRIELIHLYLTMQDRQQAATQWNILVQKEDSDRVRALHALIFEE
KPPAPQE
>SEQF2545_AGK84577.1 NADH dehydrogenase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKIVIIGANHAGTACVNCLTDLTTTNEVVVFDRNNNISFLGCGMALWIGGQIRGSEGLFYANKEQLEKKGARVSMESDIT
RIDFASKKVYGTARDGSAIAESYDKLIIATGSLPIIPKIDGMDLENVQRIKLFQDAEAVIKKLEQPSIKNIAVIGAGYIG
VELAEAFERHQKKVTLIDAMDSSLSNYYDASFRALMDENLRSHHITLAFGQKVQKLRGSNGKVVAVVTDKGEYPADMVMV
CIGFSPNTALGKNEVRTFANGAYAVDLKQETSVKDVYAIGDCATVFDNSLGQTSYIALATNAMRSGIVAAHNAAGFPLEG
IGVQGSNGINIYDLKMVSTGVTQERAARMGLEVEVTDFEDSQLPAFMEVDNHPVKIRIVFDKKTRVIVGAQMASRHDMSM
GIHLFSLAIQERVTIDKLKLLDMFFLPHFNKPYNYVTMAALRARS
>SEQF2545_AGK84578.1 hypothetical protein TPFB_0921a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSETLTLVILAAGLGSRYGSVKQIAAVGPHGETLVDYAVYDALRAGFSRVLCIIRHDIERDFRTRLFDHLAQHCDAQYVF
QSLSAQEAGAHGAALPHPARRTPWGTAHALLCARTQLTAPFAVINADDYYGRDAYKTLAAHLAAQGLDSTRHAMVGYPLV
HTLSETGGVSRGICTFADADAAVSPPTPAVPAAGRLVRAIHEHTHIGWHAHGGRRVITAQRAEDCPPHAARAPCTLTGQE
VASMNFFGFTPRVFEHLAACWQTFVQEARRAPQHEREYLLPAAVNSLIAQGKGTVRCYPSSARWFGMTYPQDRARVTAAL
ARAIAAGWYPAPLWSPDSQLRVDNVPNGSA
>SEQF2545_AGK84579.1 putative outer membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSYSWKVRALCCAGLCVGAGLRAQEGSGIRVRGMPEHAQVTVNGYLCATPEEMVLTPGECEVTVCAFGYTKKTLQVVVEE
GSFTVVDGRLDTARLELTDVTAQRAHFNPRDPAGLNTEYVTFRVTKSAKCTVTVKDAEGKVVCEEPVELVELGLNVGGIF
GGSNKNSEDVSVSAKVAFEGNVTSDPAMGQLYASALCLYRIVHNNDSSGANKCFMRKGLTFATTCAYGIKGFTVALSGEL
GASSETGIKKPDFSTDVGLSLKYQNKICSIATYSKCGTTTGSNSDGANSVAGVSVHCVLPASLVMGLENNYAFKGTSYEG
WELRASIGYVINTKLRVGRP
>SEQF2545_AGK84580.1 transcriptional accessory protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTLDQDFVDALSVQEDELAERVARELHIRTAQVTAVRSLLKEGCTVPFIARYRKEAHHCLDEVLIRDCERLFHTHLARET
RRLEIIRAVFKEGMLTPTLYEHLRSAPTLAALEDLWAPFKKKKKTRGMQAIEKGLEPLARLIETQCATQAEIERAAAALV
APAADSDRAVSSAQDAIAGACDILAEETAHCNANRAALKSFYLSAGVVTATGIGDAHAAHTSVYQMYWDYAEAVRDIKAH
RVLAINRGEREGILDVKITVDLDAAVEQVQEAVHPNNRYHRDAITDGVVRLLSPAVLREIRADLTASAEQHGINVFSENL
TNLLMTQPVKGTRVLGIDPGIRTGTKCAALDETGQYLGSFVIYPHNTDHARAALTQALDRYRIQLVAVGNGTGSHAVQEL
IASIISETHSAVAFTVVEEDGASVYSAGDIAREEFPDLDLTIRGAISIGRRLQDPLAELVKIDPKSIGVGLYQHDVNQKK
LSEELHAVVDAVVNSVGVNLNTASVSLLKHVSGVNSALAKRIVHHRATQGIFTSREQLKTVSGMGQKTFEQCAGFLKIPE
STNPLDNSWVHPENYATGKIIFDILRAGGTVSAAQKAQVQSQCAVSDRTVEDIITELQKPNRDPREDYPKPVLRQGLISF
ADLKVGATVQGKVKNVVDFGAFVDIGIKETALLHVSQMSDHFVSNPLKKVKVGDVYTCTIIGLDEARRRISLSLRQEQRA
PADHTATPSRRAPRPRAPEGKTSPERAKTRGTSPAPGQDFARYQPFAQFFKGKTPHPK
>SEQF2545_AGK84581.1 nitrogenase (flavodoxin) [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKVAVIFWSGTGHTETMARCIVEGLNVGGAKADLFSVMDFDVGTFDSYDRFAFGCSAAGSEELESSEFEPFFTSIEGRL
SGKKVALFGSYEWAGEGEGGEWMVNWVERCKAAGADVFEGKGEIAYDDPSEEAQASCKAFGERFAR
>SEQF2545_AGK84582.1 putative signal peptidase I [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSIVLQGVAAGSVLFSLLCPVQQLSVPALLAALAGAAFSCVLCVATYVLTVRQRAGAFGVVRKCIEYTPFVLMACFVLSR
AYAPTVAMPWLDSLLGMSWMVLTLCVCALLFCLRRKYVHLFFPRGVSVHTPPASSDVRSVLPDMPVRRRRGIFVVLEWVD
ALTQAACFMLLVNLFAFQLYVIPSESMVPSFMVGDRLLVFKTASGPVFPLSSFRLPRWRTYKRGDIVVFSNPHYPDTPQD
KLRAFLAQLVYMLTFTRKNINVDPVTGAPKADPLVKRIVALPGEKVMLVDGVLYTKTRHDAHFKPVAQDRTYATWDLNAL
PARDLARVQRVIFNAEELAAIHLVERLRAQVDFRDLAEKTRALVAQAHAYAGAASRTRQGIGVAQPITHTSDIPALPLFE
KEMRGAREITQLFVTVADVATHIRDTSQGFAHFAHFVQSWIPFWGQGTYGLDTGQEGPSLHRAGLSLYQIRFAQLNALVK
YTFAQLVVKGLQVTAHRTSEAGQDETLTTLLQDAARYIFFLGAARGFNMDEFPAGAEQYLPEHNYFMMGDNRLNSTDMRH
AYTEHLEAIDAHDPFPIFFSSNVAPKYIPDSHILGVASFRFWPPSRIGTPQ
>SEQF2545_AGK84583.1 hypothetical protein TPFB_0926a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFACTVFRENENALSCLPDTGYNVSLAWLGRVEEDVGYVNRAAGSCRRFCAFFPSVPGTATERSCAACCSCRSGILVCAV
RRNVCANGAPACWRFWRRA
>SEQF2545_AGK84584.1 hypothetical protein TPFB_0927 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQANTQKHKISYRNTTVCRDRDGGFMQQYSIKSDPGETSHCSIVSQTEDGYIIRICRDRDGYKKVHEVHIHQSLFDLCRR
TGFITAVRQNTDAVA
>SEQF2545_AGK84585.1 hypothetical protein TPFB_0927a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDCATVAQRNCPCQHPRSECLGSDPVIRITRGSSNCVGVLTYRGDKACAPAEIEKGLVNVHFVHFFVPVSVTANADDIPI
LCLTYDGAM
>SEQF2545_AGK84586.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKSFYFGRGALASTGGCVVLAVAALMFVFLPALSGGGHGHVRLGSWGGVALTNAPDSLFSQQYSALAQTAERYNLYPKDA
QEREGMDRRVLRAAFRAAVVQLAGTEQTKQSGFTLSEELLDREVLSFYADADGTYSPQRYQDTPEHVRLSQRKKMRDSLL
SDQYLYHLFGKETGRGGLKLNSRELRFVQDMAKKERSFRYVVLGEERFPAERVSAYGKEHAHLFTLHHLSLLTYSSEEDA
RRTARALEKRELSFEDAVATGSTKVGTDATGKMTHSYRSDVNEFFPDAQDLDTVLRTAVGALSPVVKIERGFAIVRTDAE
PSAPDFSDAATRERVFAHMARVERGTIERFLEEEAHTFSTRAKQGGFTAAAQSLNLDVHTSRSFPINFGNVDVLPALPRQ
SDPPLARIAYDEKFFSTAFALLPGQVSDPLILDSSVVLLQLHEEKSVDESVLATTGDSYAHHVRTWYPGYPLALLNTAKM
PWAQESVVDTILAHPSFKDTFDNIFRR
>SEQF2545_AGK84587.1 hypothetical protein TPFB_0930 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRFPSMGTSDVAGVRGDVPSLPPRLIKTQNGFTVLYRNTYLYSKYRAQDAHERAVARLAVKPHTLVLCCAPVLGHGLCAL
LTRMPPSSFLLCLECDLQLMHLFMQHAPRQLITAQNVYVLYTTHITQVLHTVERLTRFPFKQILKIAGSGAYAQYRNFYD
ESEQNIRTLIDTFWINKITLIHSGRNYARNIFSNYITQLQNPSHIHHLVPQSIDKPLLIVGAGPALDACRSFCARMKDTI
FLLAVDVACNALLPDIVPDAVVLLESQFWIEQAFIGTLPRTVALFADLSAFPRAVRAANVPTHFFFTPYTHAAFIKRAQN
AGVVPLSIHPSGSVGLAALQLALRLRKKGVPIFHTGLNFSWNKGFTHARGSAPVQRLYHSTTRLHSLYPDCALFPEGIRS
LKGKRYAVQSIPNLVHYAHAYRTLCAEHPHLYDLDQEGLALTTSHTVSHAQACEIITHCCTRRHRTHVPILHTQDAQISF
AFSQKPAEDFCLRVKELLTTERAALLQLKHMLTTATPSNQDVIRALIRRSDYLYLHFPDGERAEYLEYNFLCRVRAELDF
FLKLLSRIPSSLD
>SEQF2545_AGK84588.1 hypothetical protein TPFB_0931 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNKRDFPRIHFYDQDFVDIYDRTWAWIKEYWLSASGEKNTSESFFVFPEKDGLIISQHEIIFASFFFVYSNRNYDITQCL
DFFYAMQEESGAIRWKYHLASKEPVLPRANPEGIGMPLFAWAEFNLFHKTANKKRIKEIMPVMVRYMKWIETQFRRSNGL
YRVPLAATEMGNSPRKKAAYLVDFNSALAVSAFYLSALGDIINDKELSFQYKRVYFTLKTRINNFMWNASTGFYHDLDAS
GQQLPHKTIAGFWPMLGEIPNEDKAERLAEHLVNPHTFGLDHPIPSLSADEAEFDERGMGYRGSVFPPLNFVVIKGLERY
QRWDLARECSIRHLYYVLDALQLNDQTKRGVLWEAYLPTREGPAQWPGKEGFPRRQYLAYAALSTITLMIENVIGLSISL
PRKTVHWIIPNLEVMGIENLSLKRNLITILSSKSVRGWEVYMESEKLYYFTLNILGQKKKTLPIPSGKCSMLVDKL
>SEQF2545_AGK84589.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLYRKPITVCLASCSVQETHGSACDVSSIAYDSRAVREGSVFFALRGTHAHGAQYIHAAIDAGACAIVHDCPLDTYVVGV
YYARVPDARCALSSAAAAFYDFPTRALTVIGVTGTEGKSSTVSFIAQLLRLCGKRVGFISTVEYSLGDDILPNAEHQTTP
ESLTVQRLLAEMREHSCEFAVIEASSHGLSTRTARLQDVAFDVAVCMNVRHEHLEFHGSFEQYRFDKANVFRALDAHDHI
KDGRRVPSFGVLWAEDASAVYFREATHKPCFFFKRGTGAEQRTAACLERMPCTLLWVQTLPQISQALRLRFVLSTVQEPA
QPAQDGAHDVSVPLEGAFNACNIAASFLVLHGLLGTSLAAFAQHVQYVQPIQGRMQRVDMGQDFEVLIDYAHTPSSFEEI
LPPLAARVRARKRRMLVLFGSAGERDTQKRAMQGAIASRYAHVIVLTDEDPRGEDPMGILCMIAAGCEHKKLGKTLFLIP
DRVAALRHIFSLARAQDLVLLLGKGHEHSIIYAHTVQPYDEERTARELLRASLSSDTLLS
>SEQF2545_AGK84590.1 hypothetical protein TPFB_0933a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEETSHALPCVSCTEQEARQTVMGLRYSIAGLIVSDCTPSGNNLLSMLFQRRSQTVGKGHLVDSLLVINLHSAA
>SEQF2545_AGK84591.1 DAACS family dicarboxylate/amino acid:sodium (Na+) or proton (H+) symporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKIWLKFFVGSCIGALVAYTIPETLSAPLMQTISELVVSAGSYMLYPVIFFGFSVSIFEMRRERLLLRTTLISIGACVAT
AFSLSLVGLFSVLVYRPARIPIFATGTPQNPGFQIRTFFLQLFPASSFEVFTNGDYLLPLCVFASFVGAGCAVDRVAAKP
VLALFESLTRVAHTVMVFFVDMLSIGFIALSAHWLFRFRPLLSTGVFTDLVILLTLTAIFICSVLYPALIKIMCPEVNPY
RVLYAALAPMSTAFFSQNAHATLPVLLYHAEESIGVQRTTATVLLSIFSIFGRAGSACAITMSFALILKSYSHLGIGFFD
ALWIITAASFLSIFLGRFPTGGVLIALASICAWYGRGFGSGYLVIRPAAFFVGSIATTLDTLNALICTAISAERIGTVRH
RAVRFFI
>SEQF2545_AGK84592.1 alpha/beta hydrolase fold domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCYDKRMGPSRAHVHRMAKKLFKKMRFTPRTSVSALRAGYDDFFYMPYVPNGVDVSCEVLANIETDVLSPRFLMVGHAVL
YAHGGFFISGSPMASRALCASLADEVGAKFYIPAYQLAPEHPFPAALENMYDAYVALIDQKKFRPEDIIFSGDGAGAGLM
LALTHYLKQKGLVCPRALALISPWVDLTEDRFAGEGVKKKELLLTRDMFRYCALQYTYADNFRNSLVSPLFGNFGDFPPV
FVQCGEQELFHTDACALAQILEGAGVQVTLDVWPGMWHLFQSMESVSPCAHIAVARMGAWAHRMLESPAIAVQSLELR
>SEQF2545_AGK84593.1 putative hemolysin [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEKCESQPYEIFITIGFVGQRMKWDWAANIFSLLMGKSWQRQRARASMLQMSYADCAVCFDQGIGSYMVHRTDIVWVEAR
ALPSHIFSMISQHDDYNYFPVCARTIDAVVGYFSVQRYVRVCLEMERSAGASREQDEQESVTSALHVHMEGRRHAHAKGQ
GVWIADPVIARIVQQPIFVPEVISVRKLLHLFQQMQAQMAFVIDEYGGIEGMVTRDELIMRCVQEYARADGINSEDCFQN
PDGSWIVSGWMNLNEMYRLGVLARTTRPHTGVHTIAGYVLSIRNRIPRVKEQLNANGCRFTILKMDGRRIDRLLVEREHP
VPSTSGEVPSKGGGKETGDPLSSPRFAKNRKNGPGLK
>SEQF2545_AGK84594.1 putative phosphoesterase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNTLEMTAPGVIGGRESIASLHMLSCARLLLVSDTHGSAEALTAVVDQFGSCADALLFAGDGIGDVLYLCQRGRRNRVLR
ERIPGVIFMVAGNCDRASHIPLCGRIQVADVTLFLAHGHTHSVNVSDSVLVSQALQACCSIAVHGHTHVQRACVSSRVLI
INPGSLEHARGSSHAGFALLHVMNSAHTRTVFYRTRRQGHRYLFEETVPRV
>SEQF2545_AGK84595.1 hypothetical protein TPFB_0938 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKFCRGLRGARAGQFARLLCVCWCSLGACSCVRESTERSGVVPISPSSQQKVLFVFGKKYSGHVYLVDCVERVCEAWRMR
ARVVEYGDLTRLSALPRMKVVLEAVHEMRPDAVVSLGLPVGGGKYLLAVKRERAQTLIVSLLPEEEVLPMQAGSDILVDF
QVKEDSLEGVAEVSNTEAELQSLLRAACEIVRRRGVARRAHASPLQEFRGAFANVTDSLREQGVFSSDYAMECYVDPETG
VRAYNHVLLSKRVETFRFVRSYGGSPGRSVHERDRM
>SEQF2545_AGK84596.1 pyruvate synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSEKNLVMMDGNTAVGHVAHALSEVIAIFPITPSSPMGEIADEYSARGRTNIWGTVPTVVELQSEAGASGAVHGALTTGA
LSSTFTASQGLLLMIPNMYKIAGELTSAVFHVAARAVATSSLSIFGDHQDVMACRQTGWALLASNSVQEAMDTAVIAHAA
TLEARVPFVHFFDGFRTSHEIQKIEEVSYDVMRAMIDDELVHAHRMRGLTPEKPVVRGTAQNPDVYFQVRESVNRYYAVA
PSIVQKAMDRYAALTGRQYRLFDYYGAPDAEKVIVMIGSGSEAVEETVDVLNAQGGKCGLVKVRLYRPFSAECFVNALPK
TVQAIAVLDRTKEPGSLGEPLYEDVRTAIGQMQSQKKCPFTHYPLVLGGRYGLGSKEFTPAMAKGVFDNLSGKKIPNFSV
GIEDDVTFSSVDFDPNFQLDDQDVCQAVFYGLGSDGTVGANKNSIKIIGEATDNNAQAYFAYDSKKSGGFTISHLRFGKQ
KIRKPYLITQADFVACHKFTYLETFDMLKTLKRGGTFLLNAPYSEHEVWHHIPIEVQRQIIEKEVKFYVIDAISIAQKAG
MGTRINVVMQTAFFKIFGILPEAEAIDLIKKFIQKAYGKKGGEVVQRNITTIDMALAGVGLVEYPGVAGSLVTRRPAMSS
DAPEFVQSVLGTIALNQGDSLGVSALPEDGTYPTGTTQYEKRCIAETIPIWDPSVCIQCGQCAMVCPHAVIRMKAYDGKE
LEHAPSKFASCDYKGKEFGEAKFTIQVSPEDCTGCGLCVQQCPAKNKADPTRKAINMESFSKHRAVESENWAFFVKLPDP
EAKKLNLSLPKGASMKRPLFEFSGACPGCGETPYIRLMTQIVGDRAIIANATGCSSIYGGNLPTTPYTTRPDGRGPAWSN
SLFEDAAEFGFGMRVTSDKLAEYAREVGRKLQEKGVAADLFASIFSNQQADDVAVEEQRAYVNQLKKVLSESTEPLAKEM
LSLVDHLIKRSVWIFGGDGWAYDIGYGGLDHVLASGRNITVLVMDTEVYSNTGGQMSKATPIGAVAKFAAAGKEISKKDI
GLMAMSYGYVYVARVAMGANMSQVVKAFREAESYDGPSLIVAYSHCISHGIDMSKGMINQKEAVACGLWPLYRYDPRRIA
EGKNPFQLDSKEPDFKLADFMYKEVRFKTLKNANPERAEMLLKRAEEKARRQWQEYKYLADRPF
>SEQF2545_AGK84597.1 hypothetical protein TPFB_0941 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEPAVILRPLLEKGELKQSVERAQRARYVLYEVQDQGLNFVTASVLADVSAVEKMGLIRRTGKLFSDQEYCDLLNQKVFT
VHPDMRGSLKEQGVAFASVEARAYGHWYGIFEVAFPWLPLSVFEDFVLYLRDTKSLSLDEQTAAAVKESFLACRRYSERE
LDVLFERVLSGE
>SEQF2545_AGK84598.1 hypothetical protein TPFB_0942 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDGARVSDEEVARRVATLKRLKALLQEQREKFAQYLVVLQQQQVAIEAQDAETVLRHVELEEALLGDVQRVQKALAPMEQ
LCLQQASGVQELAQLRCDLSRVQEQVYAQNEKNRALLRAQVSDLRQQLDEFRAARGLVSYEDGEDSGTVIDLSL
>SEQF2545_AGK84599.1 flagellar protein FliS [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAYEDPALNAYRQVDVKTASQGELILLLYDEGIKQLGCAIELMDVQKIPASDIERVHRHILKAQEIITELSVSLDMEAGE
KIAQNLLSIYAYFNQQLFHANIQKRADELVTVRDMMRQLREAWFQIVRSPASSVTSASPASYNVNLAG
>SEQF2545_AGK84600.1 hypothetical protein TPFB_0944 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MALSVLDRAKRKFAQEKYGEVIKLLEPCVLDYHESFVFHLYLGLACLHEGIVTGAVSYLGRARQIKMSHPTLLCAEAALA
LKRRDTNRAVERYIAVLDADPKHRLAQKGLNALKAHHTPESLAGFIQSGKVKALYPRPGVAEYRRRSVVCAVGVGCLCTL
LVGALGIAGLRVWHSGLWRGTARTSRADVSFLTLTKEEYARPLEGSGSYRYTLSKQDVLQSYANAQKYFQTFKDNAAQVE
INKLLASNASHSIKRRARMLMDYFALPTFDTFPDEDNYPYVQVREQKGLYLDCWVVWQGMAANVKRTERSVSFNLLVGYD
RLTKLEGIVPVFCNFVVSVDPQKPIRVLGKVQMRGDILYLKARSVFQSVHSQSGTVSGDRQGAAAVLKAG
>SEQF2545_AGK84601.1 ribulose-phosphate 3-epimerase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MERSFTLAPSLLSADFSALDRALVYLEAHGAQWVHLDVMDGHFVPNLTFGAPVLRCLRSKTHLPFDVHLMVSRPADLIED
FVQAGADFLTFHIEAEVHAHRLIHAIRGRGVKVGISLVPSTPVAALSEVLPFVDLVLVMTVNPGFSGQQMIAHCLSKVSA
LVQMRTERGYSYMISVDGGIDCRTLPQALDAGADVIVSGSAFFSGTLRSLLCKDSSGA
>SEQF2545_AGK84602.1 glucose-inhibited division protein B [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVTPSQHALLAEGVAHLTDARTAPALCALLKQYLEELILFNTRAHLVHVTHTEELITHHLLDSLSAWPHFTNARAIADIG
SGAGLPGIPLACALALYAPETELTLIERREKRIAFLENACARLALPHLRIVHADAHDLTPYTYDAITFRALCPLNHPTVY
MLLNKLRPGGVILAYKGKRKLIEQETRDFLPQSCSVFPLHVPFLHEARHLVAIHTPCAAPPQ
>SEQF2545_AGK84603.1 peptidylprolyl isomerase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSHRGCDMNTQVWRVCVGVMLFCFVGRIGCAEEKMVREEGLAVADGIYAVMETNRGTIVLSLFFEKAPLTVCNFVGLAEG
TLAVCKGRPFYQGLTFHRVIKDFMIQGGDPQGNGTGGPGYQFPDECDPALRHDSPGVLSMANAGPGTNGSQFFITHVATP
WLDGKHTVFGKVVEGMEVVHAIIAGDTIRSLKMVRRGAAAKRFVCDQAQFDQLRKRVSAASK
>SEQF2545_AGK84604.1 Jag family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVYEFEGKTEQDAIARAAAELGLGVDQFDVEILEIQKSSLFKKGFARIRVHVAAVTASPGHAAHAQYDPVSVLSEQQFAD
LGAQLRAFLSHVFHAMGYAVTIDAFVRESDRVVVRLHSSHSAILIGKKGKNLDALQLLANVFFTKIGAKGVKVVLDCENY
RIRREEMLIRMAYATADQVSASKRSVLLEPMNPYERRLIHTTLHGISGVETRSEGEGLYKQVRVCHTGGAI
>SEQF2545_AGK84605.1 Oxa1 family cytochrome oxidase biogenesis protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKNMFIAVVLSVLVLVGASFLQELLYPSASSSHSAAEHTLSAVPEETRTQSAHGGAADTQETTQPAAHPSGQVLVFPES
ETEERVERTYVARTPLVQVTFTNRGGDILSYQLREHYAAQRREYVEMVEQARPDHRAFSLALGDEYAPNVNALFQVKQEI
DARGVHSIGFYRSVATQHADGTRTPFVLAKRYVFYPDNYMFELHVSLSADVLEEREDSRQGAKVRAVAETNAGPATTVLA
RANGFDFGTASYTLRTPPEIGPERNAADKYEFRTFMVGAGGKAKTYALKRDGREQVDTPVSWASVSGKYFALIVLPNDAD
SLKRLVLSAPQAETAVQHHIAFVRRAVAQPAVADVYRVYIGPCAEQYLSAYNVASRNPYGLERTYIDAVAVSGGILYPLE
VLLKWLLRLFYTLIPNWGVAIILVTIAIKVLFFPLTKRSFIAMQKMQELQPHMQRIQERYKGNTQKIHEEMAKLYREAQY
NPLSGCLPTLVQMPIIFAMYRLFNNYFEFRGAMFIPYWIPDLSLADSVWTLPFALPVTQWTQMRMLPVLYVVSQIMFSKL
TQVPHTEQQKTSMTIMTYVMPLFFFFFFYDAPSGLLVYWTAMNGVTLVQQLVMKRTANKNKT
>SEQF2545_AGK84606.1 hypothetical protein TPFB_0949a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSVRRLCAWVFSGLLLALIRFYQRALSPHLLPSCRHYPSCSQYAYESVRVHGCVWGLFLTVKRVVRCHPFARGGYDPVPT
KDVLPLQTDAQECS
>SEQF2545_AGK84607.1 ribonuclease P protein component [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAASRVSSRCSTVRVTFDACERLRGSCRVRAVFKQGRRFCYGRACLFVLPNGCAYSRFLATFRRGYGKAVARNRARRLSK
EAYRALKSSLVPGFDLVLLVSVVEDSLAAYQRLLCVLCDRARLFSEFTAERQE
>SEQF2545_AGK84608.1 ribosomal protein L34 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRTYQPSRRKRVRKFGFRARMATRGGRAILRRRRAKGRRKLTVSDEKKPY
>SEQF2545_AGK84609.1 hypothetical protein TPFB_0951a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSKTFRIKGADAAPPEEPVPPTRGDLDASGTFGTEWTLVFLAGGGEIGEADLSTKQAETRAEIWLSRAHGNAWWARDTPA
SSCEGTTQAHRF
>SEQF2545_AGK84610.1 putative lipase/esterase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLCLFLCGCVMKKWCGLAFSIFFSFFLRAQDLTFQEVFEVAACNDDVSLLNKMHKRTVRDNQFDEQLTDRVHLRYPASVY
YPAHQGTYPLIMLSHGWNSTQDYQRALARFLAAQGFVTVVFTSRAQRRPPDFLSTFDSVYALMQRVNEQEGSPLYRKVDF
TRVGVLGHSMGDTAALHYANRYPERIRTVVALHPFNGGADMVNMVGGKNEQLGTDLRSVRAAVLILTGTKDMLAYPERSY
EFFQSLPQDVPACFLSLKGMGHGAGTDKYFEVWGFTYNKTLSVESFALYRRLISAWFRLFLREEEEYRALFNEHGRPFRN
LKPHLSQETGRAHSYPFFCEQNISN
>SEQF2545_AGK84611.1 TraB family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDHQLTCLEFGSRRVVLMGVACTSQEAVECVRRTIRARRPQCVCVEVDDARAQDLLGMRQWQEYDLARVLREGKGFFLLS
TLALSAFQKRLSSGTGVRLGDEVKAAIEVAAELSAQVAYIDRSIEVTLRRAWRVLNPWGRAKLLAVLLSVAFTGEQLSEQ
RVAVLCAHGAMDGLMQEIISFLPAVKGVLVDERNQYLASKIWAVDSQVVMAVVSAGSVAGVQRCLYEFACGARTAEVTNL
ETVGSSPHAGQLLGWLFPLLLMGVVVTCFFAGGVGASRDALMQWLWWSGSMTALGVLCALGHPLSIVVGFVGAPIAVLTP
IIGVGLFTGFAQAWVCRPQVADMERLADDIVTFRGWYRNKFAHVLLVVVLSSIGAMIGSLISVPMLLMNLFR
>SEQF2545_AGK84612.1 TPR domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRYGTLFKVSVLLGALFVSCVSTGSNSARESERAQLLKSENPNIRFAAQLSGLLEKQRWEEALQLFDTLSPEHRAEKRIQ
YLYLSTLISAGKLTHAQELAEKLGQDGPTASETVQLWYAHAMIAQAKRDVRKKKQYVEKILAQDPHDLWALTERGYDFLS
VNDYAQAVQAFSRALRVEPRAQDARVGLGKVYYLQGKMQEAEAQYRQVLQDTPEHEHALAECARVKAETNRVLEAIRDLE
RVVQLDPHDPAYWTDLGTYLSQAGKKERAAAAFERAVALSADAYFAHIYLGGIYDELGRAEKAIEHYQRAVQLYPKYHFS
FESLGVLFWEQQRWEEAREAFATALTYAPTNISYALMTALCLCQMGQAHKAQHFMRTFIRTVDRTRREVEYFLCRLFVDL
SGEQDMASRISKIKSVPQRIRYSFYLAFFYELGGRHLLAEKHYGEVESARAPSSFEHRLAVSALGRLRGRSSSLRTNP
>SEQF2545_AGK84613.1 hypothetical protein TPFB_0954a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLPPMACGESWEELKYREVFEEELSALEHRRQRDPTCSVSDIEAVLETLYLMDGNNQDGRGNPRQIGLDATIAAYEQFLC
EWRRQLSTASPLSMEKK
>SEQF2545_AGK84614.1 hypothetical protein TPFB_0956 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRVETPAEHCLAPEHGKEMKHPSVRVCCFAFASCLLCAGCSLKRLAFSSLSHTLAPFPEGELDAHLSDADFTRVFTEEDD
LDLVAQSLPLVLKVYEALHLQNPAHRGLSLAVGRLYIMYANAFVQTPAQYLPEDEFEAQNEAYSRARKLYLRGARYALSS
LETAYPGFTREVFSGDEQRLHKVLSRCTRVDVGTLYWVGTGYVAAFALTPLGSALPDTVHAAVMMLERACDLWPSYQEGA
VWNVLTKFYAAAPESFGGGMEKAHTAFEHLTRYCSAHDPDHHITYADALCIPLNNRAGFDEALDRALAIDPESVPHNKLL
VILSQKRARWLKAHVQDFFLD
>SEQF2545_AGK84615.1 TRAP-T family tripartite ATP-independent periplasmic transporter, binding protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRTYFFMSVCSVLTCFGLYAKEKVVLKIASIAPARSIWETELKKLSAEWSEITGGLVSMKFYDMSSLGGEREGIRKLKSS
RPGQAAPLDGAVFSCLGLSELAPDSGIYTLSVPFLIQNEKDLERVLHELREDLDRPFRAAGFRVITWTNAGWLSFYTRAP
YASLGQLKKQTIALSSLDSSVLGTCFRICGFDIKDAPNARLAPLLKAGSIDGFLSVHLFTWATGFYRYISYALDTKICPA
VIGMLISDGSWARIPSRYHDAMLQAATRVRQRLANNLETLDRECSNNIQKAGVSIVHLTPQEIQEWHTEFAADVKRIQAR
LPGMLNMTLYEKIKHLLYSAQR
>SEQF2545_AGK84616.1 TRAP-T family tripartite ATP-independent periplasmic transporter, membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKGTRGQLVLRSIALLLIGTLMLLPLVLFLIERIFGFLTRGVGSEVFSAHEDFIFLFFSSSDAAVAQLAFVFSCVAGIYA
ARERKHLSVTLFSCDVDRPMHRVLSFLSAICTVAVLSACFFASGPNIVAVFRKEEAVWGVPLRWIFTALPCMYGALLFHY
AREVKCRTCVIVGLLVGVLISTGSIASVLFHLFDLTVPLLDSVFHGWVAVGTRLFWPFVLLLLLLAAQGLPLFITLLAIA
YLALSVDGGYVDTLPLEGYKILTDTGGIVAVPLFTTASLLLARGSTGTRLLRLVKEAVGWLRGGAAVACVAVAALFTSLT
GVSGVTILALGSLFKLILTGNKYPEHDAEALITSSGAIGLLFPPSAAIIIFGATNILTVHIVDLFKGALLPGTLLVLSAM
CLGVAKDRTQVRPSFSWQLLVHAVRGSVFDLALPVCISLGYFSGTLNLLQCASLTTLLAFVLGTWVRRDFTVKEACATAL
ESLPIVGGILIIVAAAKGLSFYLVDANVPDTLIAFLQHAISSKYAFLLLLNVLLLGVGCIMDLYSAILVISPLVLPLAVH
FGVHPVHASVVFLMNLELGALTPPIGMNLFIASFAFEKPIVHLTRAIAPFLLAQLGVLLLTTYIPWLSTAFL
>SEQF2545_AGK84617.1 putative flagellar protein FlgJ [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNVHRVLSLGMQSVPSVTLSKTGKMEGSGSFAARLSAAQQGAACSAEKNDALYTQAREFETLFVRVMVQSMRETLSGQTL
AGERSFSGRLYEDALYEHFSAQLAAQGGFGLAEKVYRQLNPRREAAPGA
>SEQF2545_AGK84618.1 flagellar basal body rod protein FlgG [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVRSLWTAATGMNGQQANIDTVANNLANVNTSGFKRQRAEFEDLLYQTIRTAGTPATEDTLTPVGVRMGHGVKLAATQRL
FEQGSLQHTGVSGDVAIAGEGFFRVLQYDGTYAYTRDGSFKVDAERQLVTSNGLRLVPEIIFPENYVEHSIAISKDGRVT
VRVGEQGDPVEVGQLELYRFANNAGLAAEGGNVFTQTPASGQPIPGRPGFEGFGKVEHKFLEMSNVSTVSEMVNMIVAQR
AYEFNSKAIQTSDNMLGTAVALKR
>SEQF2545_AGK84619.1 flagellar basal body rod protein FlgG [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRGWYTAASGMSAQQRRLDAIAQNLANVDTTSYKRDVAVHKSFPELLLRRVNDDGVVKNPFGSSDVSPIVGKLGLGVEV
NELFTEFEQGSLKQTQSPSDIALEGMGFFVIRTPQGEEYTRNGNFLVGVEGYLMTKNGYPVLGENGPLFLQERYYTINQN
GEIYVRPIDRPDVDGFFLDRLKIVTFENVRYLQKKGADTYMQTPVSGAPIAAEGPERPAAVQGFVEASNVNVVNEMVRMI
EVNRAYEANQKTIQAEDGMMGRLWNEVVRAK
>SEQF2545_AGK84620.1 putative macrolide ABC superfamily ATP binding cassette transporter, ABC/membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLEDIVNTLLYFRQRVLRTTLSFLGIAVGVASVVVITSIGESLYASLAQSVGEGERRLIRVRPEWDYVKNEIMFQPTESY
RTRLVQSSEDIEGVFYNSSLKALISSPHTGGKERNITGVEPRWLELKDFKLEYGTFFSPADFKTHRHCAVIGGLLAQELF
PEGNALGKRMTVTILSRASGAERALSFPFEIVGVLQEKGSLISGIPSYRVFVPREFISLEMGAGRVADAVEVCVRDVQVI
AAAEKRIREFSDFFSNKSGSVSLWSGAGEIKSFRSVLSMVSVVLSVVAAVSLIVGGINIMNIMVVTVTERRREIGLRKAV
GATCATIVQQFLLEAVLLTLAGCVCGLILGMVLSYGLFSVFSPEGITVVFSLSTAGMRTAFFMSLGAGIFFGLKPALQAS
RLDPIIALAQ
>SEQF2545_AGK84621.1 putative macrolide ABC superfamily ATP binding cassette transporter, ABC/membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVGEDFLYALHTFNARRGRTVLSLLGIVVGITSVVVVATLGSSLGASVEKLFEEDNNNIISVAPVAAHDDGVPRGQLVLT
EHVRHHLKERVAGVQGFFYLNYLQASASRRSLHAGAVSVLGVEHGWLAASGLTVSYGSDVSVIGYAVGTHSVILGKQTAE
GLFPEGNAVGKTITLYVPIGRNKVLPMVVRVAAVLKEKDDFSFSSAAQVLIPRSVLTREFSRRIADAMDLKVYDSGSIAH
VEDKVKSVLTNLTGNEKAFEVSSLHLIVEQMRSFLRAMNMVLTGIAAISLIVGGIGIMNIMLVTVAERRQEIGLRKALGA
SRMHVLHQFLVESATLTFVGGLCGVVLGLLLSVIVIAGLNAFDFQMTFSPSVVGMFIAFAGSVVIGVCFGSYPAFQAAGL
DPIQSLEDR
>SEQF2545_AGK84622.1 putative macrolide ABC superfamily ATP binding cassette transporter, ABC protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTPVVRVCNVSKVFPMGDAVVHALRGVSFEIAPAEFVSILGPSGSGKSTCMHMIGCLDRPSSGSVFIAGENTACMSERAL
AHLRNRTVGFVFQQYFLLPTLTVLENVMLPLRYQGVEYFARRRRAEDELAKVGLSDRLAHRPSELSGGQKQRVAIARALV
TRPKIIVADEPTGALDSETGRSVLDLFIEINKKGTAVIIVTHDQGVGALASRSLTLKDGKIVGDHVRGHGGADGG
>SEQF2545_AGK84623.1 membrane-fusion protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTTAQKLLHRKSTIAMVVGILAFLFVLPRLVRALRRVPPPTLSVSKEVVLNRIEISGYIEAAQHQKLESPGEGIVRTVRV
QEGDTVKKGQLLFSLENSHQQLDLAEHEFAIEQEEINGVSKKMEIMKLKRNMLQKRLRERYVTAQFDGVVAAFKLSPGQY
AKPQDYFGTLIDRSYFKANVEIPEVDASRLKVGQRVEISFPAEPSVKAVGSVTSYPSIARVTSVGRTVVDASIRIDELPE
ILPGYSFSGAIVAGEQEEILVLKQDGLRYEKGAPFVDRVLPSGKIKSVPVTVEPYVPGFVKIISGLGAGDRVKDQSAARK
>SEQF2545_AGK84624.1 putative lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIARRMLCARPWGPSCVVCALCGALAALVPAVGAQEQAVPAPGTPAPPAHTASEAVPPAPEPRAEGEQPSPLVPTALPVP
GGAVAARAAPGTVGPRLWEQLLQWRVQHGDEHQAPQMAYEIAANNYDIALVKSIVDLRMGTGHIHHNLNGNGAVGMANGT
PTLSPYVHLFFPTYQNLSLKADIAIKINTPSADVTALFGMDLYSKVRRQHQLQVRRARNSMLDAFAAHLRGQHAAREAFL
AELDELLSAYSTLLEAQVTEQECTRLVRTMRIQRYQAHSVKLRSATLKHARAERVARRARKTFTALYQDFVRKCGAFEGN
DPETFMLHLAQVVPQEPVSSTALLSVENDWEFLKNREDLETQAEARAVDAISYGFNVESGVGSEGKSLKRILANVRMDFP
GGGFWLGLNLPYRQWSRVEVKFRLTWDPLSIKYQELSRQTLQLHERLSALKLQDAYEASERKVLGLRHTAESLGWEQEAA
LTELNILRRSAQTHQKWLERGAIGAHQHARAQHAYLQALITLAKINIKILKFNLETASSFRPVL
>SEQF2545_AGK84625.1 hypothetical protein TPFB_0967 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSGPRGGSYGKRRAAVRVFAGSVLWHHAVLGGMGGAALTASELTPGAPPAVSARAAAQETGTDLYQRVVRYRLQRSTAAA
QAVRRQTITQSQYDKQRLDSLVRLFIAAGDIAWNADGVKFRITPKASVAFPSFYNLTTHFGMTVTQTNGAAGGGGGGGGG
GGAGNGWQKTLDAGAGIDLYSSVRRSHVFAVNTKYEALRDAQEALACEPHVSEKQVLEDMRRMLDSYVQLLHAQESFAQK
QNAERSVQVAGYTDRSIVYRAAALERERAQDALKVAQDAFDGEYRDFIISAGQEFLEKRADQERFLLALAESVPEMPLVS
TEHCEADTSRPLRNAREAADNEREERAVQNFPVALRLDTRFTLDEGTGELSVAFPSVKITSALAIGYTGTLKSIGGSLDW
HPFEIRYAHLRGKNQRLHDALGAREYAQKKEQQEKVIADLPQRAEDILWERETARAERDTYAESARAHRKGLDRGVIGAR
GYAAVHLDYVRAVINLAKANVDALIFNIDARVDFLSSGTQT
>SEQF2545_AGK84626.1 hypothetical protein TPFB_0968 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSVSYRGPRWSSFVHVSQHSCRFVAPTCAEGAQGCSEFGAFPVFEERGMCAARRMRRAAIVACCVFARGAAANPYQQLLR
HRLEALRPGARAQIEFDVAHCGYEKARLRSAGTYVLGSELEIRGHSAGNFGLPRFGIKPIIGVRSPRYNNLVVSIDTARV
TSIGNISRINADIGVDLYSNVRGRELIRMRRAEHEEKAAQNGERIKSPSVELALIDELEVLFTRAQSLVRREFHMGDERL
VHLRTRAAGFSEHEEKARRVRLAYDRTQREFEQEERLFAQVCDPFAAVCAVGGGDEARRDFLLQLAEAVPREVPLSLVSL
HATDAHSLAAAQEMALLERAAQQSGRDLYAVRVGAVVNMDTRKTFILFKGDGTESLEGSGTVALHMPSVNAQVEVKVPYA
ERGKHSRDKVGVYGKSQWNPLEIAYKVFERREERAQEQEQEQYFKDSLARETRKMERLEVQGKQLFAAQETALRTREALR
LDLAKVERAAARGVVGGNRLARARCEYAVAQLRAACVKLHMLRFNLGVVCAFGLVPQVAP
>SEQF2545_AGK84627.1 putative outer membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MYRTGGGVVSAGMKVLVYAVALGFGCGGVVHMREGDTYQQLLEHRIANGREFSRVFTQAQVDEAEHNEVRTKTAGSVQIG
TGDVLFNKKNGNGANGYKVEMAPHLSIASPFIGNSRLNLVAPRKLDGVTSTSTVSVDYTTDFYSSVRPTYLNSLKEKTYQ
KEKSGSALRDGRRLVEREFLQEVQRLCGSYADQVRASLELVRARLRFESVKRQGYQEDSAYFQSAQLAQVRAERARAQAR
QRFDLEYTRFAARNGVAYEDDERDGFLHDLAVAVPLEPAMAVTQCAGERGREYCDAQDRCERVIAQRGTDYSPFRTSARV
YFTDGEENKQLTNGMAAAAASTTSTYGGTFNMAFPGGDSSFTVQNSKGLAGILANFEWSPIRTRYRSLDYTAERAERVFD
EVELQAKGDRSNKLFGAIDAQGDSVLVLRGVDLQTLDNARKKARLQKERLERGIIGRLEYEAARSEYLLALASVAEAKAR
AIIFNTDLACAYGVGADAAAAQLTQEEMVVSEKKDAEEKKERSS
>SEQF2545_AGK84628.1 tp34 lipoprotein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKRVSLLGSAAIFALVFSACGGGGEHQHGEEMMAAVPAPDAEGAAGFDEFPIGEDRDVGPLHVGGVYFQPVEMHPAPGAQ
PSKEEADCHIEADIHANEAGKDLGYGVGDFVPYLRVVAFLQKHGSEKVQKVMFAPMNAGDGPHYGANVKFEEGLGTYKVR
FEIAAPSHDEYSLHIDEQTGVSGRFWSEPLVAEWDDFEWKGPQW
>SEQF2545_AGK84629.1 hypothetical protein TPFB_0971a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAHPARRLGTAVSRPTGAGCVLRRGDFHLFFYNGEEKKRWTGEGVLKRRGA
>SEQF2545_AGK84630.1 ILT iron/lead superfamily transporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MERSWEGIDRGVPVYGMGCTMVAPGMPAAFARSVIRASAWVGVALMCVAWSVSAAEGTRSGGQAQERLSSWRQVVQRMEV
HLRAAYTFFESGDSDRAYEQIDKAYFRYYEAKGMEKITMGYLSGARKAAVENAFFAYRRSVRGARDLAGVAFCRDKLVTM
LYEDARALDGVARGRAGFAAHIATFVASCVLVLREGIEAILVIAAIVAYLVKTGKERCCAAVYAGAGAGVLFSVVLAVMI
VRVLGSEGGAAQEIIEGVGMFFAAAMLFYVSNWMLSKARACAWDRYIRQKVERSVSRGNQWALVATAFLAVAREGAELIL
FFRGIPVAGPYGRLAVWAAVTVSALVLVGVFVAIRFLSVRLPLRPFFVATGAVMYLLCFSFVGKGVSELQEAGVVSRSTA
PWMHGWSFDFLGIYPTYEGLAPQAFVVALVVLSAVWWCGGLCRGASST
>SEQF2545_AGK84631.1 phenylalanine--tRNA ligase alpha subunit [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTGKADLNTLVHKLHPLEIKVLKNCAMDEILSTSLLISRLGFKEGHANQAFSWLRAKRIIEEHQREQMRSFELTPCGYAA
ASDGTAEERMLTFLSSPPSLTAIADAAEHLHPRPPLCNGLSLPELAHALTLAPKDVGSAFGILAQEGILRMDGEKRIHIV
SPHVSDRMSLTRTLLQRAAARVASPSEASDTPPGTLFESELSDDERRVMERIAKKRGASDSLFKVSVRERVTFTFTPTAR
AVQEALHTAGLTGNEIGALTVECLKSGAWKTQHLRRYNVHIPPARIIPGRSNAYADFLEHIKDRLVALGFQEFDGPLVET
DFWNADALFMPQFHPARDIHDVYYLKHPTHAPTIPEPFLSRVAATHERGADSGSLGWRYSFDRDFTRRLLLRSQGTALSA
RHLPTAHIPGKYFGIARCFRHDQVDATHLADFYQTEGIVLGTDVNVCTLLGMLKILATEIAGAQEVRYVGGYFPFTEPSI
ELHALHPALGWFELGGAGLLRPEVTDPLGVHVPVMAWGLGVDRMALLALGISDVRELFSPDIESVRLRV
>SEQF2545_AGK84632.1 hypothetical protein TPFB_0974 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMIDKLSGLDPVQNLRASCASEHVARAPAGDEITVSAEAQKKAELYLALEAVRSAPDVREYKIAAAEQKLADPAYLERAL
SHVVERFLEEQNL
>SEQF2545_AGK84633.1 putative tetrapyrrole methylase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGTLYVVATPIGNLADITLRALDVLRTVDVVACEDTRRTRALLSHFGIHKRLVSCRAHNEAQAARRLIHFLSTPISAFLS
PEKGRGRQSARRTRARPGETVGTAALQLAAEATGEQEVCGSPHAQVAYVSDAGTPGVSDPGAVLVRAVRDAGHTVVPIPG
ASALTTLLSVAGVRDKTVLFEGFLSPHPGRRRARLVQLCAQRVAFVLYESPYRVQKLLEDLVAVAPESQVVLGRELTKVH
EELCVGTALRVMESFCARTRVRGECVLLVSAEKF
>SEQF2545_AGK84634.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVLTQKNLVKRTTESTETEAVSDLLVSELLILGLSLPALLRPFSRQSRKISAIPLLPVLALSVGALTVLGQGLTLDLTLS
LVSSSVVCLTELPRLVAFSQGIPNDLYSAGARIARVLLLVAGVFTLVIVCLCAPEPGYRPSRSVVRSSFSLRLGNTKVNA
GLLLSLANPYETSHLDNPSAPHPSENPQSRAHPKQNPVGVNVVVLKNTPQSAHRAHPETLELMLAERGYTVFVPYQDAYS
PSYSAASLAAPMRTSPGVVLLSSALRGVPFDVPTPYVSRRANTIDAATFEDAHVPALFPALFALCRHAPTFVYAESAHEV
MLSRFLQQQPHACAGVFFVLPDSAARGPHHAPAVQGAPPPVDTAGVASAVRGASRTLPAVYRQYVHAAEAAWAELASTDI
LAAYLAGLPRDRHRTRLQARATQVDQWIRAQLHLSEPVLPHAQALSHHTVHAGGTYDRT
>SEQF2545_AGK84635.1 NGG1p interacting factor protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTARELDAYFRSFLNFGPFVSCDVALNGLQVANSGAPVHKVAFAVDACAQSIDAAARAGARMLFVHHGLFWGRIEPLTGM
QYRRVQALLTHDIALYAVHLPLDAHPQYGNNAGLAARVGLRQGGPFGFIRGTAVGLWGTVAENTTPSQEAMQQHAACTAP
DTHRVTHANAISPSAGLSLQQVVHRLFPAEEQPVRLLPFGKQRIERVGILSGKAGTYLAEAIALDLDLFITGEIEHSCYH
TAREHSISVIAGGHYQTETVGLQLVARKLQRDTGIETLFLDIPTGM
>SEQF2545_AGK84636.1 signal peptidase II [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIRSRPLRVDTMKLTRIQKEKWIPLFAAGLVVVLDQCAKLLVGAYVPTNTSGVRVLGDFVRIVHVYNVGAAFSIGHQLNQ
VLRTLVLGIVPLIIMFLIVFSYFRTDAFCPVQRWAVSGIIGGGIGNLIDRFLRPNGVLDFIDVKFFGIFGFERWPAFNIA
DAVIMTCGLLLIISFIKQEKEISSQPSCNETGGVLRT
>SEQF2545_AGK84637.1 magnesium (Mg2+)-dependent deoxyribonuclease [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQIFDTHAHIGLIHPDPVERLRVVQEARRASVTRIMSICNSLHDFAAVYETLQFSPSVYHAVGVSPSEVMAPGKDWIDTI
QKSLQLPQVVALGETGLDYCKKYGDKRSQIGLFITQLDIASKAKKPVIIHNRGAGQDILDILSERIPDQGGVFHCYSEDA
EYARMALDLPVYFSFAGNLTYRNARNLHETVLALPLDRILVESESPFMSPATYRNKRNRPAHTVETVEFMAELLDMDMLE
LADQLWKNSCACFHLPE
>SEQF2545_AGK84638.1 tRNA-dihydrouridine synthase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQQHALYHPVSIGPLSLKGNVFFAPVAGYSDSAFRSIAIEWEASFTYTEMVSSEAMVRDSLNTKRLIRRASNETHYAIQI
FGSNPAVMAETAKLIVDSAQPSCIDINAGCPMPKITKTGAGAALTREPTRLYEVVKAVADAVYAQDARIPVTVKIRAGWE
EAHLTWKEAARAAVDAGAQALALHPRTCAQCYAGEANWDIIADLVQCARGWGEVPVFGSGDLHAPEDARAMLEHTACAGV
MFARGAMGNPFIFRQTRQLLTEGYYTPVTFEQKLRAAWRELHLLAQDVGESSACKQMRKRFVSYAKGERGKTQWCQRAVH
ASSFADFAAVIRDACPCIGL
>SEQF2545_AGK84639.1 hypothetical protein TPFB_0980a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHDSGTGTGFVQVARRTDIVTLSIEGAARPVGQSKLGYAGSVRFSRGLKSRATYKPIHGHASRMTAAKSAKEDACTAR
>SEQF2545_AGK84640.1 GGDEF domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSYRTRSSLDRKRDYICPACNLYKAGSCARIVHPRWQGILVKECVSKEKRIYDLKQLLEISKSLNSLLEFTHLVEAILYV
AMAQTKTLGAALFTKKNAGMKKLSLSRNVCGFDVSHHAQLIISEEDPILRLLDEKACCLSPEEVQSALAPSKSVRSLLDL
QPSLFVPLRAKDHLVGLILLGKKINVHEAYTPYDQSIIMDIAQLAAIAINNALLLEQATTDMMTQMKLKHYFFAMLTAKL
DTLSTQETVSVLMLDIDFFKQINDTHGHLCGDLVLQHVAEIIRSCTRPCDIASRYGGEEFMLMLSNNSSREAAHVAERIR
VATEQLTIPYHEVSIRVTVSAGVAEYLPNQESAETLIKRADSALYQAKQNGRNKVVISEKNMCSSQE
>SEQF2545_AGK84641.1 rhomboid family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSVIRKPFRYSYTNVTLSLVLANGAVFVITSLVESLGIYLALVPGLVRYHRMYWQIFTYQFVHSGVWHLLFNMLGLVFFG
QTIEKKMGSSEMLLFYLLVGTLCGAGACAAYLCVGRLNVLLLGASGSIFAILFLFSVMFPTALIYLWGVIPIPAPLLIVG
YILFEIFDLFFSRDNVSHLTHLLGVLFAWGYIRIRFGIKPLKVWSIVP
>SEQF2545_AGK84642.1 hypothetical protein TPFB_0983 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSRNSRGSGRYVFVVLACVFGYTRAVHAEVYTDPSTSGHVTISIPIWAFVEPQPGVMTQQAESPRTPPRQTLRELGAFVL
GGAVYGWRFSYTPKEKKRAVMEHFTLTPIFPLPPDSPQISLRHVRTPYPYIHCRAEYSLDARHATHMRQSRNLTYQRAQG
RGRGERKEELKGVYHAYHRAIVDALRKTVRKTQKNKPKEVEGMLYVKDNPRLFVEAGEFVAELSLSVHFTKITPYSVY
>SEQF2545_AGK84643.1 chaperone HtpG [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAQYEFQTEVSQLLTLIIHSLYSHKEIFLRELISNASDALDKLKYEALVDGTYKQLHCEARIDIAFEEDAQRLVVRDTGI
GMNAEDLRANLGTIARSGTKAFLSTLTRDQKQDSNLIGQFGVGFYSAFMVASKVEVITKKAAENTVWKWTSEGQNAYTLD
EVDAAAFPVLEGVAEGSAGTCVVLHLSQENSEFATRWRLEEVIKKYSDHIAFPIYLHYLQKEYDKDGAVTDTQKKVDQVN
DAGALWKRPKSELKEEDYHRFYQTLTHDSTPPLLYVHTKAEGTQEYVTLFYVPAKAPFDLFHADYKPGVKLFVKRVFITD
DEKELLPVYLRFVRGVIDSEDLPLNVSREILQQNRVLAAIKSASVKKLLGEFKRLAECDGKKYDEFITQYNRPLKEGLYS
DYEHREQLLELVRFRTLSESVPEDGWTSFAEYVSRMKPDQKAIYYIAGNDDRVLRQSPHAESYRLQGFEVLVMSDDIDGI
VMPSVSKYKEWELRAINRLGSEEELRPNEETDAAAQREQGFKPLLERLTHILSDSVKEVRLSKRLSDSVSCIVIDENDPT
VQMERLMRATGQTHKSKIKPILEINASHTLVQKLKESTDEAFVEDLAFVLLDQALLIEGMDVGSSVDFVKRVNRLLARG
>SEQF2545_AGK84644.1 hypothetical protein TPFB_0984a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRPLSVDPSIEHNYRSDVAPAQLATSYSPSRIIHDLPIIPWGVSAIQSRVLLSGVHRAACTTCSGWFTVLHSLCYTSRAV
CARRNGIFFNLWEDTWLSTSFKLK
>SEQF2545_AGK84645.1 aspartate--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDYPRRTIACGELRRCHVGTVVVLNGWVHRKRSHGTVSFFNMRDRSGIVQVIVSQEENASLWSTVNRIRLECCLAVEGVV
RERPPSMINRALHTGEVEVHARTLYVLSENAVLPFRVDDVVHAHEDIRLKYRYLDLRSQRMQERIALRSRVALAIRQFLS
MKGFIEIETPTFICSTPEGARDFVVPSRVCPGRFYALPQSPQLYKQLLMVAGFDRYFQLARCYRDEDARGDRQPEFTQID
LEMSFVSRDDVMRVNEDMLRYVFRTSIGVELPTFFPRLTYAQALDQYGTDKPDMRFKPVLQNADFMGMLGTFTPFEEVVA
QGGSIRALVLPGKARCYSRRQIEALESIARAHEAHHLFWLKATGGGLEGGIARFFAGVESEVRRRLSAQDEDLLLFVADC
RHRVCCVALGAVRSALIRDESFPEKELFSFVWIVDFPLFEWNPAENKWDPAHHMFSAPQEQYLETLEQDPGSVKGDLYDL
VLNGYELASGSIRIHDTQLQKRIFKIVGLDPEEAGEKFGFLTEAFKYGAPPHGGIAHGLDRLVMLMTGSESIRDVIAFPK
NTLAASPLDNCPSVLDKRQLDELHLTVHV
>SEQF2545_AGK84646.1 DMT superfamily drug/metabolite transporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAFTEKQKGTLCLMCSSFCFSVMSVFVRLAGDLPSIQKAFTRNLVSTLISGSMLFRARTRVHVQDLPMLSLRTVCGTLAI
VANFYAVERLTLADASLLSKLSPFFTILFSCLFLGERIAPYQVVALCGAFAAGTLVVKPSHTLSHRVFPACIGAVGGMMT
GAAHTCVRYLSTRGVEKFLVIFFFSFGSLLLLLPAFIWQYQPMSSPQVLTLWAAGVAVAGAQFFLTVAYRYAPKKSIPID
YTHILFSTGIGFLYFKEVPDHWTVAGIGIILAIALYVFARERERKEPTVPSHTR
>SEQF2545_AGK84647.1 hypothetical protein TPFB_0987 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MCGYSARAAFFLAVALTVGVCVAACKTAPRADTHFVHTFVADMFHISYGALPCTVHFEHAEHETYRTDINGRITVPLGGR
RVIGVSYDFTQYQRPSGRLLARKDFLHVVAVRDAPHDGKYAVEVPVHVTRTCLILLPRKI
>SEQF2545_AGK84648.1 MarC family multiple antibiotic resistance transporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSTWTHIWSTAFTLLFIIDPIGNIPVVLSVLRTVPAERHTRIIFRELLLGLVLMLSFLFCGKVFLSLFQLETGVMKMAGS
VILFLVGIKMVFPDQHALPSTTEEEPFIVPIATPMIAGPSAFTTLVIMGETKGTSRLATCAALLVAWTLACLIMISAPCL
YRLLKEKGITALERITGILLLILSIQMCVEGARGIIATS
>SEQF2545_AGK84649.1 hypothetical protein TPFB_0989 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKSARRTGFPLACACISRSCARYGFRVCRAFASSPGPVVWGCVRGGALCRGGSRNSMRGCALGVMLVLSGAVGLCAAGLD
PTQRRALIESISRVEAPRIQGRCVVFTASGAARHVGIAFEHEGYRPIYSFVRLSQESAQNLTERSVLFHIAPIPEGCSRL
SYRLVIDGLWTTDPENSFESYDHRDGMSISYLDVPSHESYQTQHTAAGTRFVYQGAAGQTIHLAGTFNNWDPFMYSLEEV
RPGHYELELPLPPGRWLYAFVKDGTSSFDTQSNARAYLADGRVANVVVVP
>SEQF2545_AGK84650.1 hypothetical protein TPFB_0989a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTPSAHPLIEFLDPPRQSAPPRTHPHTTGPGELAKARHTRNPYRAQLRDMHAHAKGKPVLLADFTPPQKKPIRGRGV
>SEQF2545_AGK84651.1 conserved hypothetical outer membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPSAQHLSEFARELKTLGNEPDTLKSWGTLYDDLPPPESTPDGAQPAPTPERQSAPASASASGPVSAHGQRPFEPDTEAS
SVASGEEVVQEDAHAPQTRMHDSAQEPAAEISLFSEERTPETMPTAAWSAPPDPLFETEHAVPPLPLDPEETPVPGEKGL
QESAVQEEDAGFNQMPATGGQTSENQQHFDALLASLDLDSANGERVVPENADEFAAQVPESLLEGLHPEDQETKRSQEEP
VSYDFPAFDLDQVAPPTPDAPDSSNSALTEIEITPALSEHPTQTQETGTTSPQSQTVHADASALGPSASDPNFSPGSADN
LVAQFPIEESVQIPPFPADGFELPGKFQEFARESESPYFSPDTTADADQAQTISETEYQRFLQRLDALPLPVRIAVQEYL
SSEETSDKEGYALISSIANNASPKAVATQLEHILKKPLHIPRKFERKSAAAHEREKSSLPYIAKHTVLPLTASSAAILIF
ILSLAVLSWHFLYKPLHAHLSYRAGYHALELDRYEDAHTNFEHAKQYWKIKHWYFRYARALRDKKQYTHAEQIYTELLFD
FRHPKQGSIEYAHMLCNELRKYEQAETTLRRQGLDHHPNDPDILSALGDVYLEWAEEDPAQYEQARKTYQSLIASHGTRD
AYLARMMRYFIRTDQLAQVLPLKAHFTNTRARIAPEDLTELSGYLLEKRYESQPSDSLTLQSKIEDLRALLERAFKADPM
SADAAYYLGKFFVYNHRKDSARELLQQAVNRYPHMPHSTVRRTLREIDAMRLLGTLLLEEKGHAAAREIFTQALTRYRSY
IVMRDLPPHRTIGKLYRDYADMDYFIYKNYDSALEHYQHARAQLLDTPEVQYKIGYIQHKKNNYPEAIRAMNAAYEHNPQ
DKHLLYGFGTLLCKRGDYFASQGYYEQLLELLDAQRTRRGVMLPHIEKADAAFVDLYMRTCNNLGVVLHRLATTHGDSRK
NARALTLFAESSRAWDALTRHPETRVRSQATGLSYLNVHHMTRPYTEFQPELYDDIPLLLEHEEPPIQKEQEN
>SEQF2545_AGK84652.1 rubredoxin [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGTYMCDLCGWGYNPEVGDADGGIPAGTAFENLPDHWECPLCGVDKTSFVKV
>SEQF2545_AGK84653.1 hypothetical protein TPFB_0992 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKKKDAFVGTIGYDGQRAVVDRARVLKHSRSSLQELLSAGAFREAAACAVWERSTEALEAVASAYNARSGSRYSAQDIAK
VFGIASEPGEKAVVL
>SEQF2545_AGK84654.1 putative rare lipoprotein A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MMDKRVVAVAAVLWNVQMLFAAGEVIVPEGYASYYAESFNGRPTASGEIFDMSAYTAAHRTLPFGTVVELTNLDNGKKVI
VRINDRGPYAANREIDVSKAAAVALDMLNAGVARVSIHKADPNAHASQQRNDRQTSPGVLPQDSFGVSPTAPTSSAPVMY
ADPHNPPPAPVGRRAGTPGVPGVANTTDVPASEYGAPPVAYAAPGSTPSRVPYGTAVPGSAAPNSHAQPVPSSSSYAAAA
PLPYAAGGGKVSGMESVYTPTHSGETRGVLWRIQLGAFVREENALRLVVKLREAGFDPSYERTEHAVRVVLPGIRPADLE
RVKHALKRGRFHDYVIRQESW
>SEQF2545_AGK84655.1 hypothetical protein TPFB_0993a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRNGLRRRPNPYREVQTRRKRAPRAGLQEQSLSFLIIPCARTDLHEKREACKVQLSEEGLRILTLLYKQRKVAVRITVYV
DLPATYPLQWQHGRTTLE
>SEQF2545_AGK84656.1 magnesium (Mg2+)-dependent deoxyribonuclease [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEVGTRAGDYQERKALLLQACAGRSLPSCLHFSVGVWPAPEPIAHPETALSLLRSDVRALCAEQAPYRALGECGLDRHWN
GPQVACKARKGSGVRGTPDLDAEEYLFKAQLSIAKAQNLPLIIHSRDAFEPTLRCLDSVGWRKGVMHCFSYGVVEAHAFL
ERGLYISCAGTLTYAKTTSELLARDALIRSIPLDRLLLETDTPYLAPVPHRGTHNRPEYVRHTYALVANILGISEKALAQ
HVFANCCALFEAQEPTEACSQAHAPTRYT
>SEQF2545_AGK84657.1 putative CAP family transcription factor [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSKIPLISTVTSTISAINGACTGERVDIHIQTLSRLNEIASVFRFEMPEIKIIDFGDPNVDSEACLKIIKDDPWLLFGGV
IAITNSMEEKIKIVNRKDPNFLSVSTRQEFEAHASQVVRIVDRNRHFLSSRSLVHQAHGHEQGNFICDTDSFEITFYASL
ISSYLYNTNRINELERTSFEGAMMELLLNALEHGNCGISYDEKTEWLEQRKDIFDLIALRKQDPRISAKKIYISYDITLQ
RTRITIRDEGTGFDWKSRMASACKPGLHGMGIKMTEIFVKRLSYNDVGNEVTFEIDNQENVANLVPSILKNQQVLTFRDA
QVVCYQNEESSSLFYISSGKFAVYVDNKFMSMLTPSDIFIGEMSFLLNNRRSATIVSVGEGTLVKISKMKFISLIEDHPH
YGIYLARLLAGRLAHQSRESAKLKNTLTLLGQRTPDTGAQAIPS
>SEQF2545_AGK84658.1 hypothetical protein TPFB_0996 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQEVRGSIPLISIAVCEGGGVSDLGLDPDLLALLQDTPQGVPSEHSSAGKGTAMSPTGTRDPSDVDLSERSFPLVTEFQS
KTPHQFFESAEFYKRVVSDELEVGQRAHAALARYLSTTDLKDRSVCRQQLISSYWQLMAQISGKIGGGSACMEKRYALRY
GLLLPTLLTASQKDIFARIIETNSLQQPLYYLDEWLIAIGSGKVRPSSTDEVQVKRKDDVARVRQAYDKACGQLQSSERL
LQVRSAERARVEEEVKNRISRLFVHESIEGLPGVTAGFNEAQKQGISEIHELLKKLLGIDREFNGLYAGYRASQDAVHSL
REKLDAPNAENSSAVSTEYDTVRQMIKMSCGRQGNHFPLLSREYFRSAEHEIGTRENVLKIMAWIEGLDPEAYCRQYKQQ
VNRIPPFVVLLPSYGDIGFCWEPFDRYNRVTSRGRVAVPMYGRSLKRAVITATADLRWQVAKEKASYYWMEEGLTGNYYQ
WFQPQKLRGDVKEYFIADYTTWLLKESEGIQKLDKEVRNVFWRYIPFPQKIKDELKTKSFVYQELCQKDANRQVSDGY
>SEQF2545_AGK84659.1 signal peptide peptidase A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEVTMYSLRVLFRRLLRGLNAVRLVSLNVIFFLLLFLFFKVLVGDRSRRPSQKVVQSGTVLLMRPVGVVTEQRPRVNLGT
VFLNPKGSAILLSDITQALRNAATDRRIESVFFDLSNMSGWTSGHFVEMESALSEYKKSKKPLYVFSTSYSLADYYIASF
ADEIILDPMGSVDLSGFYTETLFYGGMEEKIGVRWNVVHAGVYKGMAEIFSRKDFSPEVRRNYQSVFARLWQQYLSDVSR
NRALEVQHLARYADRRLELLQKYNGDGARTALAEKLVTRVCSYDEAGVALKFLKEDDYESAKNFVGLDDYNRDRAQRQVQ
DQVGIIHLAGPIAAHRDTELGGTISDEVSALLDVAMSDPDIKAVVLRIDSGGGEVFASERIRRALARAKRRGKKPVIVSM
GAIAASGAYWVASAADYIFASPYTITGSIGVLSVLPTFETFLERYAGITVDSVQVHGVRQPSLLRSGTAEDTARMQLDVM
ATYRTFLSVVSAGRNLTLDRVAAVAEGRIYAGEDAVSLGLVDALGGLDEAVAHAAKESHCRQYSVRVLKRSATYGEEFLQ
SLWDVLQKRSLAFGERVIIGELLQLDLSKGTYVYEPLRLHWR
>SEQF2545_AGK84660.1 sodium/alanine symporter family protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTAFQALLIRLVDALHSYILVGWLVVCGVFFTIKTGCVQLSLLKPAFAALAEKRGKGVSSFQALMISTASRVGAGNIVGV
ATAIAFGGKGAVFWMWVSAFFGAASAFVESTLAQAYKTRTACGFRGGPAYYIEMGLKSRSMGVLFALCLVFAYAYGFNAL
QAYNVVSTLSYYGKDSSLWVQILAVLLSFLLAFVIFGGVARISVVSSVIVPVMAVGYVFLGLWVLALNVYRLPALFFEIC
REGLSLTAFAGGTFGSVVVIGIKRGLLSHEAGMGSAPNAAASAEVSHPVVQGLVQALSVFIDTMLICSVTAFVLLLSDVA
GSVDVSGMQFVQRALSKQVGPVGVHLVTLAIFLFAFSSLMGNYYYAESNVRFIKDHKMVLSVFRVTCVSAVFVGAHASFH
FVWGVADLFMVFMTVINLIAIVTLHPVALYLLRDYRKQYRAGNVPVFFQEHLVFPEKMACRE
>SEQF2545_AGK84661.1 S-DNA-T family septal DNA translocator [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MERSPLPRIIALTFGTLLFVSAVLLTLSTFLPLFTLHRASHWFFVPGTLLYETYAFSSLLVPLLLLHTALLLFVGGRSLR
AESALVAFPLLFITAVCGEHGLYALRRALAARSISPSTRGGIDIVCVLCLLALLGAELYAALIYGERCYVWFHARIPRDF
IADGFQDPSFPPSTADHPDTVSPPPAPSCATADVQTPEASAPPEGQFSTEVPLQGGEFLISEAEVQPATQVAACGGVSTP
TALAPSVPSQAPFPLLPAPGLIQSNLPSDVHAPASPGSLPSVIPAQAPCVMALSPISAPSVAPAETLIPAQDDEQGPPRP
IPASAAPLRHPCRGYQVPYDLLDQYSEDTYEGIDELTKNLALLLEETFSEFNIRVEITGIKKGPVVTMFELLPPPGIKLS
KITNLQDNVALKLAASSVRIVAPIPGKHAIGVEVPNKKRSLVTFKELLHTRTAGSNRMAIPVILGKDVTGEPQVIDLAQT
PHLLIAGATGSGKSVCVNALILSILYHKCPDETKLLLIDPKIVELKLYNDIAHLLTPVITEPKRALQALQYILCEMERRY
ALLEQLECRDIKTYNKKIQEKSIATQPLPFIVIIIDEFADLMVASGKELETSVARLCAMSRAVGIHLVLATQRPSIDVIT
GLIKANIPSRIAFMVSSKMDSRIILDEMGAEKLLGRGDMLYMNPSQSFPTRIQGAYVSERELARVIAHVRAWGTPEYLDE
EIFFDDDDASISGNFVDESDPLYEQAVQVVQYAGKASTSYVQRKLKIGYNRAARLIEEMEARGVVGPPNGSKPRDVLRS
>SEQF2545_AGK84662.1 hypothetical protein TPFB_1000 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQAGDTLPFYSNADYQPHRRKGVCSAAHRADVQRGETMMREDVRMHVLRRRISFHYRVDPLKGDSFENNWANNSCDTMQL
QDKAGRVLYGAMVQTVANYCFGRMAPGSGVAHGESVAPGAFVVRCFVPARAFHGRIHAITRTWDMDGEWIDREAMQISTE
GYQTGRWLIHDRWSEKLGRDTNYAWSAGCFVLSSEDLRRMNEVLDRWGVSCGQEMAGILEELE
>SEQF2545_AGK84663.1 hypothetical protein TPFB_1001 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQSYEGGVWLTCDIMGVSLFLVREHVVMWDLHRALCAGLLSVLLYGGCSSARDFVHVMKTAGNEVALVHYALQGDCIVFG
FRGEVSDVVARVHRAEGVVSEEMSDELLQSFTDEIPSALSRIAVPAAYQESVDAARERLSFFAVRFLQKPHVGQQVVLRG
SAQDVAHQKHDFVLPFEGINTQPARLEISEVRPLYGNKRSEFVELLVVESGNLLGITITNVGGKGNRCDYHFPAAQVRVG
ERVVLHWRKQDPASCDELSAETVSAGSQACARARDFWGQERSIPGRNPNAIVVKESANGKIQDALLFFNTHVKKGKAPTF
RWAFPEIEAASRLALEQGAWLSTHEHFPLRESHFFQCDLTPAKSIALKRKRGAGRSAADCFVLKKATMGLPNQ
>SEQF2545_AGK84664.1 hypothetical protein TPFB_1002 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRTGCVGNRCKRIGTVRARGEKQRRIAWVCYLAAVFLTLCTKSAMAGDIATFVNLGFSAHGKTFAFGQHGVTDGLYQAY
ADIYVVDVESNRFVQGGVVRTTPTRETKGKRSMDVFLALQNRAQSLLQRADISALRLGRTLYVQAEDRMGEETLLFRDFK
TNVEYVVVMHVERTTELGVSFYLTVEMTRPNGSKVSRVVGQRGYVRPGVKNYALKKVLINEQQDALIFVVEKHGYAPDGA
SVRYMVEACRL
>SEQF2545_AGK84665.1 putative membrane protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTIAGRNKVVAFSIVLSALLCSISLLQAAFVLSGGSLPQLAVARVPPLLHTTGRAFMHVLTFLLPEAAARSLAAVSTAPS
NSSTLVAILGTGLSAPLLLTYLLRRFEKTHAVEISYFSLFLCALNFEGVRLFLPILYTGTLTTYAGNVPMQIVMFFRSLA
LLALFASGIFAKKTLTRQEGAVVFVLCTVAFLISRYTTIHTIHAYRPSQSTQGAILLAQPISESGSIIDSTGEEKTLKVR
SSAHRKTRILVTPQRNFTFYYGSHAWHRWFFWTTAVLSALSYGVLGHTLQISHYYIAAAALPFVIAGYRLLTHGLTWSAC
IVGLFLLNTASVFFIRSVHRVHIWQ
>SEQF2545_AGK84666.1 recombination protein R [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIPAIEEVVEHLSRLPGIGVKLATRLAYHLLKRDPAEAQVLARGIACLHERVYRCVCCGAFCEGRTCALCTDASRDRGII
CVVERAQDVEMMAGVGEYRGLFHVLGGVIAPLEGVGPDQLRIAALLKRLQESSVREVILALNPTVEGDTTALYVQKILAN
FPVIVTRLASGIPVGGDLEYIDRTTLAHSLRGRRPLDCSEA
>SEQF2545_AGK84667.1 DNA-directed DNA polymerase III gamma and tau subunits [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAYQVTATRYRPQRFQHVLGQKFVVATLQKSLEENKVSPAYLFSGPHGCGKTSCARILAKALNCVQREASEPCGECPSCR
EIATGTNLNVIEIDGASHTGVGDVRQIKEEILFPPHGTRYKVFIIDEVHMLSNSAFNALLKTIEEPPPYVVFIFATTEVH
RIPATVKSRCQQFHFRLVDTQTLVCALAQAAQQMQIAVEDGVLSWIARESAGSMRDAYTLFDQTVVSCAGPVTLENIQKK
LGLMTDDSLAALFSHCCRKDARAALELVDALVSSGVSVEQCVIDCVRYARALLLFTQGITNESLVGIAANQVPEYVRTTW
NASQIERALGLLLQLFRDIRFSVDPRYELELAISRLAWLSEYVSIQEVRVALDSVQQILDTHAVPGVCSASVGSDDGETG
VVSPHGIRPPMSTSVCTVRALQDALVEKLRASHQMLATALGSSYSWREEDTSVCMCVRTHYERSVISQHASLLKEYASEL
LGREVCVRVLLDSVPSSKVAPSHLPQSPAPSALFTTSLLISGQECDRVSGDLPAQVKLLCDCVQGHVVRVYEGTARCVPG
EGKIAGAVRTPY
>SEQF2545_AGK84668.1 DNA topoisomerase (ATP-hydrolyzing) subunit B [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGIEYSASSITVLEGLEAVRKRPGMYIGSTGPNGLHHLVYEVVDNCIDEAMAGYCDRITVVLEQGNVVRVEDNGRGIPVD
VHPHEGVSALEVVLTKLHAGGKFDKKSYKVSGGLHGVGVSVVNALSLWVEVTVYRDGAEYYQKFNVGMPLAPVEKRGVSE
KRGTIIRWQADPSIFKETVAYDFDVLLTRLRELAFLNSTVVIQLRDERLATAKQVEFAFEGGIRHFVSYLNRGKSVVPER
PLYIEGSKSDVLVEVALQYHDGYTENVQSFVNDINTREGGTHLEGFKSALTRVANDFLKKSPKLAKKIEREEKLVGEDVR
AGLTVVLSVKIPEPQFEGQTKTKLGNSEVRGIVDSLVGERLTLYFEQNPGVLTKILEKSIAEAQARLAARRAKEAARRKS
GMDSFGLPGKLADCSLKDPAKCEVYIVEGDSAGGSAKKGRDSKTQAILPLWGKMLNVEKTRLDKVLHNEKLQPIIATLGT
GVGKDFDLTRIRYHKVIIMADADVDGSHIRTLLLTFFFRYLPQIIEAGYVYLAMPPLYRIAWSKKELYVYSDTERDEALE
SIGKKSGVAVQRYKGLGEMDGTQLWETTMNPVRRKMMQVVLSDAVEADRVFSTLMGEDVEPRRKFIEENAIYARLDV
>SEQF2545_AGK84669.1 thymidylate synthase (FAD) [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTLRTLQAGVAVSIALDRVCFFCYNGAVAHCVVEAAEDILDRRFSVLDKGFVRLIDYLGGDARIVQAARVSYGAGTRTAR
DDAALIDFLLRNKHTSPFEQVVLTFHVRAPIFVARQWMRHRTARISEVSSRYSLLSHDCYVPQETSVAVQSTRNKQGRAS
EGISPEQQQEVRAAFEAQQRAACAAYDALIQKNIARELARINVPLSLYTEWYWQIDLHNLFHFLRLRASAHAQAEIRAYA
EVIIEITRAVAPCATASFENHEKDGVQFSGREFAALKALLAGEGLSLEGKERARFEEKLRSGLQQ
>SEQF2545_AGK84670.1 ribonucleotide-diphosphate reductase subunit alpha [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHIIKRNGEPQPYMREKIIVAISAAFRSVQNPLAPEVPAIITDLAAEVERQLFEMNRAGVPVHVEKIQDFVEKTLTKYNH
SDEVKSFILYRDDRTKKRIAREQIACCFTDSSVLGVLKEIQQDFPFPEYSLDALASKFLLFKKEVTDERRSMQLLIKAAV
ELTAQEAPQWELIAARLLMLDFSLALGTSLEKLNIHSFYEKITYLEEAGLYGVYIRTHYSRAEIEEAATYLECSRDKLFT
YSSLDMILRRYVIRTRAHVPLETPQEMFLGIALHLAMNETQDRMQWVKRFYTVLSKLQVTVATPTLSNARKPFHQLSSCF
VDTVPDSLDGIYRSIDNFSQVSKFGGGMGLYFGKVRAVGAPIRGFQGAAGGILRWIKLANDTAVAVDQLGVRQGSVAVYL
DVWHKDIPEFLQLRTNNGDDRMKAHDVFPAVCYPDLFWKTVRDNLGASWYLMCPHEILTVKGYALEDFYAEEWEKRYWDC
VKDARISKRTIPIKELVRLVLKSVVETGTPFAFYRDHANRANPNGHRGIIYCSNLCTEIAQNMSAINLVSVKITEVDGQK
VVVQTTRPGDFVVCNLASLVLSNIDLSDDKELREVVRVAVRALDNVIDLTYYPVPYAQVTNAYYRAIGLGVSGYHHVLAQ
QGIDWESDEHLAFADRIFERINRAAIEASMTIAREKGAYGCFTGSDWCTGAYFRKRGYVSEDWQRLQREVATHGMRNGYL
LAVAPTSSTSIIAGTTAGVDPIMKQYFLEEKKGMLMPRVAPSLSQKTCPLYKSAHAVEQRWSIRAAGLRQRHIDQAQSVN
LYITTDFTLKQVLDLYVYAWEVGMKSLYYVRSQSLEIDLCGYCAS
>SEQF2545_AGK84671.1 glycerol-3-phosphate dehydrogenase (NAD(P)(+)) [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MASIAILGGGAWGTALAASLTVNGHTVMLWARRRQTCDAINARNENVQYLPGITLPAALCASPDMAYVCAGADLIVLAVP
SCYLAEVAALMNTTPRFQRLRTAAVGQEYPLIGILTKGFIPDQEGMPHLITDALGALLPSGAHGQLVYISGPSHAQEVAQ
GKVTGLIAASQNPMAAIRVRELLRSKRVQVYSSLDVVGVQVCAAVKNVIAIAFGLLDAMAEHSEAFGDNTESMLLAAGLN
EIQTIGKQLGSTHPETFTSLAGIGDLDVTCRSAYGRNRRFGRDIVHKGILDSFSGIQDLVSRLPEVGYLAEGVVACMHVQ
RLAERDRLKVPICAGLYAILNREKGADTFMQEILGW
>SEQF2545_AGK84672.1 nucleoside-diphosphate kinase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAFETTFVMLKPGVLQRRLVGEVLSRFERKGLVLTALRLLCVDTATAELHYAEHREKPFYPSLIAYITSAPVVALAFKGE
NAISLVRTLCGSTRVEHAQPGTIRGDFALRTTTNIVHASDSPESAARELALYFSAQDFVEWRDGNYDFF
>SEQF2545_AGK84673.1 aminoacyl-tRNA hydrolase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGIQLIVFLGNPGAEYEETRHNAAWLLLTYLFPSIVLPWRCGCRGSIARIEGFEGSSEEVWLLKPLTYMNRSGKSVGAAC
AFLQTDAKQLLVVHDELELPFGVVSLKQGGGLGGHNGLRSIKEVLGTADFWRLRIGIGRPPSESVNIAQYVLSAFYPAEM
AAFPKLGRATRDLLCQLVVTDQAATVTLLSAWRKKRLLSLCE
>SEQF2545_AGK84674.1 DNA-directed RNA polymerase sigma subunit RpoD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLSIWYVPFEQKEYSVRQMQFRHDENTLTAYLNDLKRIPLMNEKEEYACACAAYAGDAQAKNALVRANVRFVISVARHYR
TCGLPLADLISEGNIGLLTAAERFNPARGCRFISYAACWIRQSILKALNEKARIIRLPVSRIRAAKSTYEYIPPVTSVNV
GISKTQGGNRYGKRRATMCRAVPTVEEVHIWHTPLSLDAPLGASGSRGESGDVDGLRIGDCVPDDLYAQPEEHMLACALQ
ADIAKILRLLPARDAQVIRYRFGLGGYERRSLQEIGEIFQITKERVRQIEKKALLRIRSCARQHRLDSYIA
>SEQF2545_AGK84675.1 chaperone GroES [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKIIPLADRVLVKTDKSETKTASGIIIPDTAQEKMQSGTVIAVGSDSEKIKVSVGQRVMHDKYAGNPVKIDGEEHLLLKG
TDILAVIE
>SEQF2545_AGK84676.1 hypothetical protein TPFB_1014 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MLKVRSKRHLLSYLGVVGVGIAGLCIYRSVWGSRPFLERLARADSLIAQERKGAALRGLARMVGHARESSQYLSIAKRQM
ELSASAAALRTLQRGIRRSADDGRLAALVIHLLLREARFEEAISYVPRVVHKGYESIGAEALIKAALIGSRTGGDSPSRG
SFHSERAEHVPEEPVEFSQVQGGRDQAHVTAFPLDRGEEQFRVEPSPPIRHTTGIALARIAPALWLAAFGVTGMHAFLQN
AACAYARVGELHAAFRLYSRILGTEAPENTAFWATVAYDAGQFSLVFELLPISLARADLFGTYSAASTHARTHLLLAADA
AFDGGDRARARAFWYAYVDRFPGTSTHALYNLALTAPHAQERVRMLAQCVEGDKTYYPAVACYARESIAFRAAHRQRDSV
TELLSERGVYSVQMEQEHFLSPHFPVEARSLLAELAQEAMHGRADVRFALEYFRFCYPAQKRLQGSRGALWQLLEVFPVD
TQVRRYARWFFFRIGEYESAFGLSDAGGGPEDAFYRALAAASRTGRVESILGGLVEATRAVEARSAAFANIAIVLERMGK
KTAAAEHFVLAADEATRESVRQLQKEAGEGEAEEHPRARPAAGKAQRWREWYQRAGQLLQQQGKTVAARALLQRAQAR
>SEQF2545_AGK84677.1 transcription antitermination protein NusB [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSEVFPKIGRRRARILAFQALFAWDAAGITPETLTQFTWLRRNPPPSTQDLGFSRLLFLGTLEHLREIDGCVSSRLEHWD
FVRLNKVDKAILRLSAYSLLFQKDIPPVVVIHEAVSIARDFGTDDSFRFVNGVLDNIAKSA
>SEQF2545_AGK84678.1 putative peptidylprolyl isomerase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MGRYIVPALLCVAGMGFAHAQSALQPIAEVNLFRREPVTLGQIKARISAIEKEMGKKLSTAERRQFMDSLIDEKLFAQAA
EKAGIQVTDAEVNQYFNGMLSQQIGRAVTEAEFANYVKEKQNISLDQFMKQQNGMTMAEYKKFLKTQVSTQRYVAQKKAD
EFRNLKGPEDSQIRSYYELNKQAFFRPDTVKLFLISVPKGSGPAAAKAKAQEFVKKLKSSGVKATADIKSKANGAQAGYS
AGEIYLGKTAVTATQLGLTMEALLEIFGMGVGAVSDVNETANDYQCFIVLKKEEAKILTLSDLVEPDKTVSLYEFIKNLL
TSQIQQKALEDAIREVSAELRKSGTYKVFLADAELGKVLDW
>SEQF2545_AGK84679.1 alanine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSIPIRADQLRSRYLAFFSQKAHVVISGKSLVPEHDPTVLFTTAGMHPLVPYLMGEPHPAGTRLVNAQKCLRTGDIDAVG
DNSHLTFFEMLGNWSLGDYFKEEAIAFSFEFLTGAPWLGISPDRLSVTVFAGDEAVARDEESAAIWERLGIARTHIHFLP
RADNWWGPTGETGPCGPDTEIFFDTGVPPCSVSCRPGCSCGKYVEIWNDVFMQYRKDADGRYRPLERYCVDTGMGIERTV
AVLQGKRSVYDTEIFTPLLERIGQLCGKRYGCQGAHDVSMRIVCDHIRAATFILGDPVPVRPSNVGAGYVLRRIIRRSVR
HGRKLGIDGEFLSSLARVVIGQYAAVYPELEEKATCIAQELANEERKFLDALRKGEAEYERMIPKFLQGTEREIPGSVAF
RLYDTYGFPLELTEELARESGLRVDRAGFDTAFQAHQACSRIGAQRVFKGGLADHSAETTAYHTATHLLHQALRVVLGTH
VQQKGSNITAERLRFDFSHPRPMSAQEKVQVEQLVNEQIRADLPVCCEVMSLEDAMNSGAVALFGEKYESTVKVYSIGTF
SREVCGGPHVARTGQLGRFSIQKEQSSAAGVRRIRAILEKSGEKS
>SEQF2545_AGK84680.1 hypothetical protein TPFB_1017a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MVHPKVKPTVTRTTPITIDVVMCVLLIFFKGAKLSCERLEVCANSVKDLVARLLRESPFLFPV
>SEQF2545_AGK84681.1 hypothetical protein TPFB_1018 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTTSIVIGVVLVTVGLTFGWTIRWLYARFHLSACEQRAERILQEAQKEAESKKKSILLEAKEYVLRERNQQERDDRDRRA
ELQRAERRLLQKEEALSTRAGELDSRERSLKQRDQSLCQEEARYRQELERVSGLTQNQARDLIIKNLENEAKHDAQALIN
KIEEDAALNAERRARDILVTTMQRITADVTGDVTVSTVNLPSEEMKGRIIGREGRNIRALETLTGADVVVDDTPEAVVIS
CFDPVRKEIARISLERLVLDGRIHPARIEEIVQKVTQEVSQKIYEEGEKVLFDLGIHDMCPEGVRALGRLYFRTSYGQNV
LYHSKEVALLASMLASEIGADVAIAKRGALLHDIGKGVETDSDRNHAEIGMEMARKMNEDPRVVNAVGSHHNDIEPCCVE
SWLVQVADAISAARPGARREMVDHYVKRLENLEAIAEGFSGVEKAYAIQAGRELRVLVNNDKIPDRDVKALGRDIAKKIE
SDLKYPGRIRVTLIRETRVVEYAR
>SEQF2545_AGK84682.1 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferasesubunit C [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MHGRPCRFASAAVTLLPPYSSPAILVNKAHGSIMAQQRITSDIFAQLLTLSHLESSECAVGLATQIEDIIQYFSVVEQFD
PGPRDDPDTDNAQGRCSQGNKIDVDCCPDWVRKDVALPGLSVHDLKRLSTEFADGYFRAPRALDGSA
>SEQF2545_AGK84683.1 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferasesubunit A [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDAHAITCASWNMLKAQLEAGAISSLQIVRAFRNVYEEDTRSASPLGALVEFFSDAEEHARTADNLRASCAQSTKTAGAN
GGSVSGKPLLGLPFAVKDNISVKGKHCTCGSKLLADYRAPYDATVVARLRAAGAIPLGRTNMDEFAMGSSTEYSVYGPTR
NPRDRSRTSGGSSGGSAAAVAGGQAPFALGTETGGSVRLPAAYCGLYGLKPTYGLLSRYGVVAFGSSLDQIGFFATCIDD
IALALSVTSGKDLYDSTSTCPPPATGRHAVSHHLAPFSAHECSTLRAAVPRELVDAPGVHPDVSAQFQRFLTWLRAQNVQ
VEEVTLPALQAAVPVYYLVATAEAASNLARFDGIRYGQRGDTDALLENYYRAVRTSGFGPEVQRRIIVGNYVLSRHFSGD
YYRTSVRVRSRIEQECTQLLCSYHFIVCPTAATGAFPLGERIHDPLAMYCSDLFTTFVNLARLPALSVPVGTSGTGLPIG
IQIIGSQWQECAVLRLAKRWEEAPHV
>SEQF2545_AGK84684.1 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferasesubunit B [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSDLQTGTVPSIAGATDDTHAAPFFYEVIIGCEIHCQLLTKTKAFCACANRSGGMPNSRVCPVCLGLPGALPVVSEEYVR
LGVRAGLALGCTIQLWSAFDRKHYFYPDLPKGYQITQYDAPLCTDGAVDVQGVDMPVQRRVRIERIHLEEDAGKSLHAAD
AYSYIDFNRCGVPLIEIVSRPDLRSAEEAACFMQTIREILTFIEVTDGNLEEGALRCDANVNVRILYKGQEHHTPISEIK
NMNSYRMVRDACTYEVQRQLQEFWQKGPASKEEMQRKRTMGWDPVEGVTLLQRTKHSLRDYRFMRDPDLPDLHLTPAYVQ
HLSYTVGELPAARRARFKLDLGLSAFAAQTLTGSRMLADWFEKAAHASKNARRVANWILSEVLAVVNEKNICIAELNLSP
EAIAELMDAVEDQRITGKQAKDIFAQMLATGARAQDIISAQGLAQLSDEEEIATLVQTVFQEHPKALRDWQHGKTNVAAW
LMGQVMKRSRGRAHPARVATLVHQALSQL
>SEQF2545_AGK84685.1 DNA repair protein Sms [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MAKKTERAFSCVGCGYVHPKWLGRCPECGEWNSFEETPSLSSGDVRAVKKASSSPVQAFPLCAVRAQDAQRISCGIAEFD
RVLGGGAVRRSAIMIGGEPGIGKSTLLLQIAAACGKSVLYVSGEESPGQIRGRADRLNIPIQNIELLCATRVEDVERVLN
TRCPTFVIVDSIQTVFSPEAGAIPMTINQLKYCANELIGWVKERDSVLFFTAHVTKDGNIAGPKVVEHMVDTVISFERNE
EDIRFLRALKNRFGSVDELGIFTMGENGLSAVQDTAGFFISTRQGMFPVGSATVPVCEGSRVFMVEIQALTVPAKSSVTR
VFSDRIDSARVSRVAAVIEKRVGLKFSDQDIYVNVAGGIRLYEPAVDVALAMALYSARQNTPVKTNAAFIGEVSLSGEIR
PVRRLKTRLKTAYGLGFSTIYVPIGVEHDTPPPYTLRVVGTLAQTIAEIFSKAKA
>SEQF2545_AGK84686.1 recombination regulator RecX [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MASAVHGVDFNSVSDRRFCLCAIQSLQEDVLKLTDEVGAVLQTRLSYLGALSCPIEELVGTRPTDEQYGAVCFACRCYEA
ECVAVRLLARSETSAQQLGFKLLKRGFEKRVVESVFPVLKRYSWLDDTRFARAWLRNRVDSRPASRAQLLGELKRRGVSH
ADAEGALDLLFQEQDEETLCLRLLEKLRRRGYGPHTLQRALQRRQFSPSLVRRCLAVETEGA
>SEQF2545_AGK84687.1 ribosomal protein S9 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKNLGIGTGRRKTAVARVCVRMGNGNVTVNRRDVGAYFPTAEQLRRVREPLFATANERRYDVIVNVYGGGLDGQAGACAH
GIARALVRADASNQASLRAGGLLTRDSRMVERKKYGQRGARRRFQFSKR
>SEQF2545_AGK84688.1 ribosomal protein L13 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRTIFVNEREAVRAWHLIDAAGRPLGRVAARVACLLRGKHKASYTPNQEMGDYVVVINAEKVFLSGTKPKDKMYYRHSGY
PGGLKSVSFSALVKRRPVEPLRHAVKGMLPKGPLGRKLIKNVKIYAGSVHPHESQNPVPLSC
>SEQF2545_AGK84689.1 hypothetical protein TPFB_1025a [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MPSANSLALINKDCPHPSAPLSTRSGSLRVGARSRMFATPTRRDIKPAKIPPTGAAPRKNRSASCAHPRPQPYSIGERRA
KTAAPISSTPTKTAPTTASRAKSPDRLIKIILCQAALAQRQLECVYSPDSCGKLPEETFC
>SEQF2545_AGK84690.1 putative oligoendopeptidase F [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQRFEDIPYTRPHMDILEHAVDAAHGEFAQARCARDAYASILAIEDLQRQYLTAQALANMRCSIDTRNTFYRREQDFFDA
VHPRFARLDHAFNQLLLASPQRDGLEKLIGTHRFTLARLQSKTFCSEIMEDLAEENRLTSAYETLLASAHILFRGHHYTL
AQLSPFMEHTDRNTRRDAHEAYYHFFAQHESELDTLYDTLVRVRTRIARTLGYDNYIQLGYDRLLRSDYDMQDIARYRTY
ILRYAVPLAAELHEQQRSRLGLSELLFYDEPLYFPSGNPVPQGDAPWILNQAACMYRELSPETDQFFTFMREYHLFDVCA
RIAKASGGYCTTLSTYRAPFIFANFNRTAHDVEVMTHEVGHAFQAYQRYRARLDPCLEAYVWPTYEACEIPSMSMEFLTW
PWMGLFFGEQKERFYLRHLTQAVELLPYGAAVDEFQHWVYAHADASATERKKAWRALETQYLPRRRYGGQHYLSCGGLWM
RQSHIFCIPFYYIDYTLAQICALQFWDRSRVAYTHLSTLTGAAPYASITPTAYAEAWHDYCVLCSRGGSEPFMRLLATAN
LHNPFEEDTFVSTLASCRAYFRTVGDRLS
>SEQF2545_AGK84691.1 uridine phosphorylase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKLVYSTDCEYHIGLKASDIGHYVILPGDPARSEKIAQHFSHPHKVGHNREYVTYTGTLCETPVSVMSTGIGGPSTAIGV
EELIHLGAHTFIRVGTSGGMQPDILAGTVVIATGAIRFEGTSKEYAPVEFPAVPDFTVTAALKHAAEDVQVRHALGVVQC
KDNFYGQHSPHTMPVHAELTQKWHAWIACNTLASEMESAALFVLGSVRRVRTGAVLLVIGNQTRRAQGLEDIQVHDTENA
IRVAVEAVKLLITQDSPR
>SEQF2545_AGK84692.1 excision endonuclease subunit UvrD [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MESYLSALNEAQRQAVCHYGSPLLILAGAGSGKTRVITTKIAHLIRSRQVRPEQILAVTFTNKAAREMRTRACALESAAQ
GATICTFHALGVWILRRYAVRLGLNPHFSIYDDHDVRALLPKILPHCDHSRAGMLARGISQAKDYGLDCASFESVHARVS
APACAARAVLGDRQFAHAYACYHRRMREMGTVDFGDLIMLPVQLLREHQDVAEQLHARWQVVMVDEYQDSNVAQFHFLQV
LTGAHTYLCVVGDDDQSIYRFRGAEVKNILTFPEFFQNTQIIRLEYNYRSTDAILRVADSVVKKNQDRLGKALIAQRTGG
TKPRLFLLNNQDEEAALCVHLIQEARARGIPYADWAILYRVNAQSLSFEQCFLRNRIPYRIVGTLKFYSRAEVKDVLAFL
QLIVNGSDELALRRVLNKPPRGIGEKTQDALFVCAQQAAITDFTTLQSTHLTALGTRARQKVSSFLSLLRALRARMPQAP
AAGEEARTSAPPEEPVEERTHDAEGLARFVSVVMEHTGLEEWYRQKDEEEGTQCAVNVQELMNAASLYACSHEGLVSFLE
HIQLDQNMADEGGAADAVHLITIHNTKGLEFRRVILTGLENGVFPRDDEADIQEERRLMYVACTRAMDSLYLTACAYRRM
WGRHTAMKPSRFLTELDSALLEITDPRHFA
>SEQF2545_AGK84693.1 DbpA RNA binding domain protein [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MSKISSKISSVDQEKFQAFLQQILRNVKTQEDPRVLDAYRRLFRKSVPFSMRSYVAAHLAHTHCRAGATAGSTRRTGARE
GIRTGSAHAPSCASAPASAARARDFERKARDYPALCPGDTTSIFISIGKNRHIYPRDIIALLMQRADVAREHIGTIRILD
HYSFIQVLSGEAEAVIARLNGLFYRGRTLTVSHSRRADEHPAPSTEPHAAAVAPEPDFMAEPIPALEE
>SEQF2545_AGK84694.1 Tpr protein L [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRCHENGHVRCAAARGARGDTKLPLRTENCKYSAPPPPCLPEEGAELRLKDLTVDFESPKPGQAFTLKKPKASFEATLHC
YNAYLTIGKDPNCFINFAQLWDPFVTSDYKQEDVRYAPGFGGYGGKLGYRAQDIGGSGIGLDVGLLSFASNGMWDSGTAH
SKYGFGADATLTYTHHRAERIKMELAGNATLEPQYTTGTEQGKNNEQKNRLLWSAGGRLTLTPGYGFRLVLALDVGNIHR
SDADIGKTVNVQAKAAEAVSAAVTEFWAQVAQIMANGGVGEFFVKKVRGAALIAQVALVVSHLEGKLSNLLQSTLGLGAV
VNQLTQGFAELLKKPDPAIALVTFFAWLHRLHVHELGADALLSMQWKWLSSGAYFATAGANMFGRRVFSRQCTDYLDCAA
FLKLETKSGDPYTHLLTGLNAGVEARLYIPFTYTSYVNNGGIDYNRTTMRGPINLPVVGKTWLSYQIALGSHAWLKPYAV
VYGTTNRFNTDKANNLLREKAMQYHVGFTVSPIEKVEFDARWEQGRLATAPYMLITEDISSDKHFGTFVCGLKIAW
>SEQF2545_AGK84695.1 hypothetical protein TPFB_1032 [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MACGENERASTSPPNRAAAARGGRLTLLDGCCVALVLALTAWSGFFVYRMQGGARTLDIRCGAQRWTYPLDQERVIRVRG
PLGETEIEIRAGAARVCRSPCANGTCIAHPPVQRVGEWNACLPNGVFLYVHGTDAAEPEADAVQ
>SEQF2545_AGK84696.1 patatin family phospholipase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MKWSLVLSGGGARGIAHIGVLKALEVLQVPPPQCVVGCSMGAVVGALYALGMSVREMEAFFQRDFVISDYVNARDPSACV
EAGMVWGARAAFQRLGKLVQLGVSLNTLVRGLGLDSGEKFATLLTRVTGGKSFHDCKIPFLCNAVNLCTGAEVVLSSGVL
ARALRASCAYPGVFAPVRQEGVYLADGCILNNTPVWIARAQGFDAVLAVTFDRFEQLGLSDFRTGFDVLLRSLSCASHAV
ATQARNYPSACVRVETRRDQSDFSRPQELVARGYAAVQHARAVLDVFFARGVRGMLGRRRLARQARAYFER
>SEQF2545_AGK84697.1 CaCA family calcium (Ca2+):cation antiporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MESFVRSALAARTLPTLLGVLLCALYFLARSADCLVESASALSRRWGISEALLGATLVSLGTTTPEAAVSVYAALCGNAD
LALGNAIGSIVVDTGFILGLGALLARPGLALDTHLMRRHARVQLFAVCALGWVTLPRFGARVHQYVGWLFLSLLALYLWV
SLRWSALPHAPDTRTAALPADKTDTRSVCRLLLQLGGGIGFLVLGSRVLIPTVEIMALRAGVPAGIIAATIIAFGTSVPE
LVSAITAVRRGHGALAVGNIVGADILNVLFVVGAAASLTPHGLPVPKIFSLLHLPAMLLVVGIFHACALGRRTLTRPAGV
LLCAVYGLFVLLNGLLRGTGP
>SEQF2545_AGK84698.1 valine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MTQKLQKIVLPPVYGPADFEARVYACWEQRQAFSPRARGSGTSDSEGCDGHSRQIEGGARTFVIAIPPPNITGVLHMGHC
LNTVLQDIVIRYQRMAGACTLWIPGTDHAGIATQHVVERALRKEGIHKREVTREQFVARTQQIKDSHQDTIRMQLRKMGA
SCDWTCERFTLDAGMSASVREAFVTLYERGLLYRSMYLVNWCPRCGTALSDDEVFHQEKDGALYYVRYPLLPRTEEEGNG
VPPPLGTAQVGETIIIATTRPETILADVAVAVHPDDARYQSLIGRKVCVPMVNRIVPIIADSYVAQDFGTGMVKITPAHD
PNDWDIGTRHSLEAINMLNPDGSLNDQVPAAYRGLSCAQARIQIVADLQAHGLLSREERIVHSVGVCYRCEAVIEPYLSL
QWFVKMKPLASQALAAWKRADVQFHPKKWENTYVRWLEHIRDWCISRQLWWGHRIPVWYCAQCAQQTVSRVDVQRCAHCG
SADITQDPDVLDTWFSSWLWPFSTLGWPQETQKLRAFYPTSAVITAYDIIFFWVARMIMAGLEFTQTVPFRDVYLHGLVR
DKQGRKMSKSLNNGVDPLHIIRTYGADALRFTLAFMCAQGQDVLIEMDSFKMGSRFANKVWNASRYILGNLEGRRVYAIA
HVSLTELDRWIFHTFNETVQQVRTALEAYRFNDAAQAVYEFFWNSFCDWYVEASKCSFQKPDEQEKDRAASVLCTLLEET
LRLLHPFLPFVTEEIYRSLPPSVHDTTQAIPSGAHALLMCAPYPVYVPSRVDARACAHIGAVQEIVRAVRTLRAACGIDP
QKAVSVRLRPSSPAQDANAAAQVSCVHDPGAVARTYEELICVLAGISSLVYLESDAPKPQVAVATAGTGFELFLVTTEGI
DRTMLCARLQKAWQKARQKVQQVERKLADAQFCTHAPEEVVTAERKKLAEARATCHTLAGYLADMNGKPGPLSDSD
>SEQF2545_AGK84699.1 P-ATPase superfamily P-type ATPase transporter [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MQVSFVVHGISCTACVRRIEEAVRHVTGAYDVYVNPTTSHLYVHTDLHPTEHTLFAQTIIDAVSHAGFKATLLDTHSTTA
PLAATQPVHPDFVTLKRRVRTSLCLLVPLMYLSMGHMVHLPIPGFLHPLKYALSFALVQAFLTLPVLYANRSLFRAGLIA
LYGAILRRNTATMDSLISLGSLSSFTYGLFATARIAMGVHANDTALVSHYVADLYFESAAMIVTLVTVGKYLSALSKGRT
SRALTQLLDIKPKTARVIRQVSVPRGASPSSPTTASAASAHETHEIEIEIPAQDVLVGDTVLVKAGELVPVDGIITSGQA
TLDESNVTGESIPVEKGRGDSVISASLVSTGFLKFRAERVGEHTTLAQIISLVEKTAASKVPVTKLVDAVSAYFVPSIVA
LSLLSGCAWLCAGASAEFAFSIAVTVLVISCPCVLGLAVPTALMVATGKGAQMGILIKSAQVFQQMARTKVIAFDKTGTL
TLGRPTLSHIHTLHPTYNEEDILHLAYSLEVCSGHPLAAAISVAAQRKGMTPLAITDFNSEQGLGLRARLVHTSYAKTVM
VGNARMMVAHSIDGMDTYLSPSHNPEETPLFVAADKNLVGVLFVSDPVKVHSSAAIGALHKRGIQTLMLTGDVKHVAHTI
AARCGVKKSKAELLPHDKEREISALKASGMMVAMVGDGVNDAPALASADVGIAIGAGSDIAVESADVVLMRNCIRDVVTL
VDLSIATVRNMKQNLFWAFFYNTLGVPLAAGLGYPFFGLRLTPMLAAAAMSLSSVSVLCNALRLNQFQSSSP
>SEQF2545_AGK84700.1 putative hemolysin III [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MEKIVNADGSDAICPASAACAKSIRSYQESYSLGEEIANAVTHGIGVGLSIVALVLLVVRAVHYTPADLTARYVVGFSVF
GSSLIVLYLCSTLYHALPRGAKYVFGVIDHCCIYVLIAGTYTASCLTTLYGAIGWTVFGVIWGLACSGSVIYSVFGHRVR
WLSLVMYIAMGWLVVFVAKPLRERLPEISFLFLVLGGVLYTVGCVFYALKRIKWTHTIWHMFVIGGSVMHFFSLYLSF
>SEQF2545_AGK84701.1 bacterioferrin [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNMCTDGKKYHSTATSAAVGASAPGVPDARAIAAICEQLRRHVADLGVLYIKLHNYHWHIYGIEFKQVHELLEEYYVSVT
EAFDTIAERLLQLGAQAPASMAEYLALSGIAEETEKEITIVSALARVKRDFEYLSTRFSQTQVLAAESGDAVTDGIITDI
LRTLGKAIWMLGATLKA
>SEQF2545_AGK84702.1 adenine phosphoribosyltransferase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRGIGRYHAPMDGHAALDRAIRKRIDFPKKGILYYDITGVLMNAAVFRYCLDQMVEFYRDEHVTAVAAIESRGFIFAAPF
ADRMGIPLILVRKAGKLPGDTYSCSYSLEYGKATVEVHKSDVVAGARVLLTDDLIATGGTLNAARTMLRAGGAEVVGFFA
VVGLPFLRYHELIGDLPVRTLIEYNQETSN
>SEQF2545_AGK84703.1 lysine--tRNA ligase [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MDTESVLFRAQCLRAVRDFFLEHHYIELDTPALARALVPERCLEVFQTEYFTSVHAKDTQKLYLVPSPEVFLKPLIAQLQ
RSAFQISKCYRNGESMGALHRPEFTMVEYYTVYADYKTSLDVSSKLFRFVVEQVQSHPLADPYSCACFCAPFEYVTVEEA
FLRYAGFSLSHASSVQTLAQEVLRSGIDLGARAGVDYTQWSWDDLYELLLVHIVEPKLRSIKDRCVVLYDYPIQISCLAQ
EHTGRSGIQSTSPNKGDAPHWVVKERWELYVRGVELINCYTEQRDAKHVTRYCREEQTAKQGSARVVHPVPEGFAHACAR
MPPCSGAALGFDRLVALLAGRHSLDAFVYDQ
>SEQF2545_AGK84704.1 S14 family endopeptidase ClpP [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MRCDATQEKRAHSESGESVFFQKFLETRQILLSGEISKDLAEGIVRQLFVLESLSVSKPIYMYVDSPGGDVDAGYAIFDV
IRFVKTPVYTIGMGLVASAGVLVLLAAKKDCRFGLRNSRYLIHQPLSGMRGVATDIEIHARELEKTRSKLNALIASETGV
SLDKVAQDTNRDYWLDASQALEYGLISNLIEKRADLPKK
>SEQF2545_AGK84705.1 V-type ATPase, V(0) subunit I [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MIVPMKKVTLLVLGSEQERSLQALRSFGAVHVQLRECASEQLAELHALDARCVQAIALVTDAQTKNVTRGEECRVAGQVV
EAAEAVEQIIRTHSDRVELAQRIAQCIAHLERCEPWGDFDPADVRALAQRGIHLIPVELSERSYRCLPDELQTLCLARRG
GLVRCVLVADKPGLPPSLPADARALELPDVSLADLFVRLRQLREECATLTQRLLAYSEYQGAIRALRQKIAADIEFERVH
LSMVSVDVSQWRETGETLRIAHVSGYLPVSRVRAFSECARKEAWAYCCVDPMPEDPVPTQLRNNRWVNLISPLMNFLGTV
PGYWEVDISGFFLLFFGVFFSIIFADAGYGAVLTLVSLGGIVLSKRKHAVVSPAWCLGLYLGTLTMVWGALVCNWFGVPV
QYVPASLARIAVWEISGFADAAQRNKNQMHVCFFLGLLHLCLGHLIVVRRTFRSLRVLAEFGSLLMLGGMYVVVLNLIVD
KERYPLTGMIVGSIIAGFVLNFIFVNYRVSVRQSVADSMKNVINALLGIVNVFADVMSYIRLWAVGLAGGAISATVNEMT
HPLFANFLAFLGIVLLLFGHGLNYVMSILSVIVHGVRLNTLEFSNHVGLMWTGIRYTPFRER
>SEQF2545_AGK84706.1 V-type ATPase, V(0) subunit K [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MNFGMFGAAAVLGISAVGSALGLALAGQGTIGSWKRCYLNNKPAPFILLAFAGAPLTQTIYGFLLMKAMLSSEKDPWYLL
GAGVACGLGIAASALSQGRAAAAGADALAETGKGFSQYLTIVGLCETVALLVMVFGIINC
>SEQF2545_AGK84707.1 V-type ATPase, V(0) subunit I [Treponema pallidum str. Fribourg-Blanc] [HMT-805 Treponema pallidum Fribourg-Blanc] 
MFRSQRMKFLELVVLERDVDRVLEYLGKTALVHLRLSAAARGSSSHCAQSKEYVGRLEEACKYLGVSGECAFSPGDSLPT
EEDYTLAQQILAEVDALHAREREGDAPSVPRGKSSVAHDSANEEQFQGEKCALGSMRGPALCALLRRFALQERVHRTRDA
LESTRHTYRIAGWLPAHEAKDLVAGLDNVTTGRMAVRLFEPQELSFIRDGSEHVPVCYQHGRFVRSYERMVSSYGCPPYG
LVDPTPFVAFSYALLFGIMFGDLGQGLLFFVLGLLLRTRRVRALNRWAHLDYVFLSVGFSSMVMGFLTGEFFAHGTLLAP
LIRSVTALCGGVPRDHILHLMPSHGSLHTLMAFFGFTLFLGFVINSLGLIINIVNQVRLRHALAAVCSKTGVCGLLFFWY
MVALAVRIPLFGIPFGVFDAVAMGVPLVGIFCQEFLERVCKRVRPWFPEGVGMYLMHGVIEMVDVVSGFFSNSMSFLRVG
AFALSHAVLSFVVFTMTQFVGGYASLWGILVYVFGNGVIIFLEGLIVAIQAVRLQYYEFFSKFFTKSGSVFAPFRFGYQE
D
